BLASTX 7.6.2
Query= UN11402 /QuerySize=895
(894 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7TNK6|TRM11_RAT tRNA guanosine-2'-O-methyltransferase TRM11 ... 209 3e-053
sp|Q7Z4G4|TRM11_HUMAN tRNA guanosine-2'-O-methyltransferase TRM1... 206 2e-052
sp|Q05B63|TRM11_BOVIN tRNA guanosine-2'-O-methyltransferase TRM1... 206 3e-052
sp|Q5R962|TRM11_PONAB tRNA guanosine-2'-O-methyltransferase TRM1... 206 3e-052
sp|Q9CWH5|TRM11_MOUSE tRNA guanosine-2'-O-methyltransferase TRM1... 205 5e-052
sp|Q6NS23|TRM11_XENLA tRNA guanosine-2'-O-methyltransferase TRM1... 189 3e-047
sp|Q6YJI5|TRM11_CHICK tRNA guanosine-2'-O-methyltransferase TRM1... 186 2e-046
sp|Q12463|TRM11_YEAST tRNA guanosine-2'-O-methyltransferase TRM1... 158 5e-038
sp|O94636|TRM11_SCHPO tRNA guanosine-2'-O-methyltransferase trm1... 139 3e-032
sp|Q54QA6|TRM11_DICDI tRNA guanosine-2'-O-methyltransferase TRM1... 90 2e-017
sp|O26820|Y724_METTH Putative RNA methyltransferase MTH_724 OS=M... 51 8e-006
>sp|Q7TNK6|TRM11_RAT tRNA guanosine-2'-O-methyltransferase TRM11 homolog
OS=Rattus norvegicus GN=Trmt11 PE=2 SV=1
Length = 463
Score = 209 bits (530), Expect = 3e-053
Identities = 109/268 (40%), Positives = 168/268 (62%), Gaps = 17/268 (6%)
Frame = +2
Query: 80 FLCVFYHRLLDFRKPEVEALAELFGEDESLLQWRLPEHHHNDTPFHFVHLSSEEIAQNIA 259
+L + L+FR PE+++L + G Q+ + + +PF +++ SE+IA+N+
Sbjct: 10 YLLLMAQEHLEFRLPEIKSLLSVIGG-----QFTNSQETYGKSPFWILNIPSEDIARNLM 64
Query: 260 KRSILVKGMYELWGEGASYEELKDSIQSFPDSRKLPFLDSDSTFRISVETFGKALTFDEQ 439
KR++ K ++ELWG G S EEL S++S+P + +PFL SDST++I + TF K LT +E+
Sbjct: 65 KRTVCAKSLFELWGHGKSPEELYSSLKSYPVEKMVPFLHSDSTYKIKIHTFNKTLTQEEK 124
Query: 440 RERINSLTYIPFEGKVNLKKPDHKFFIIEMDESEENNGLQPILQRRIFFGREVGFADRKL 619
+RI++L ++PFEGKVNLKKP H F I+E D + N + P I+FGR + R+L
Sbjct: 125 VKRIDALEFLPFEGKVNLKKPQHVFSILE-DYGLDPNCI-PENPHNIYFGRWIADGQREL 182
Query: 620 LPTFQLKSRTYLGPTAMDAEMAFLMANQAKATSGKLVYDPFVGTGSILVSAARFGAMTMG 799
+ ++ +K R ++G T+MDA ++F+MAN AK LV+DPFVGTG +L+++A FGA G
Sbjct: 183 IESYSVKKRHFIGNTSMDAGLSFIMANHAKVKENDLVFDPFVGTGGLLIASAHFGAYVCG 242
Query: 800 ADIDIRVV----------RDGRGPDCNL 853
DID V + RGPD N+
Sbjct: 243 TDIDYNTVHGLGKASRKNQKWRGPDENI 270
>sp|Q7Z4G4|TRM11_HUMAN tRNA guanosine-2'-O-methyltransferase TRM11 homolog
OS=Homo sapiens GN=TRMT11 PE=1 SV=1
Length = 463
Score = 206 bits (523), Expect = 2e-052
Identities = 107/268 (39%), Positives = 166/268 (61%), Gaps = 17/268 (6%)
Frame = +2
Query: 80 FLCVFYHRLLDFRKPEVEALAELFGEDESLLQWRLPEHHHNDTPFHFVHLSSEEIAQNIA 259
+L + L+FR PE+++L LFG Q+ + + +PF + + SE+IA+N+
Sbjct: 10 YLLLMAQEHLEFRLPEIKSLLLLFGG-----QFASSQETYGKSPFWILSIPSEDIARNLM 64
Query: 260 KRSILVKGMYELWGEGASYEELKDSIQSFPDSRKLPFLDSDSTFRISVETFGKALTFDEQ 439
KR++ K ++ELWG G S EEL S++++P + +PFL SDST++I + TF K LT +E+
Sbjct: 65 KRTVCAKSIFELWGHGQSPEELYSSLKNYPVEKMVPFLHSDSTYKIKIHTFNKTLTQEEK 124
Query: 440 RERINSLTYIPFEGKVNLKKPDHKFFIIEMDESEENNGLQPILQRRIFFGREVGFADRKL 619
+RI++L ++PFEGKVNLKKP H F ++E D + N + P I+FGR + R+L
Sbjct: 125 IKRIDALEFLPFEGKVNLKKPQHVFSVLE-DYGLDPNCI-PENPHNIYFGRWIADGQREL 182
Query: 620 LPTFQLKSRTYLGPTAMDAEMAFLMANQAKATSGKLVYDPFVGTGSILVSAARFGAMTMG 799
+ ++ +K R ++G T+MDA ++F+MAN K +V+DPFVGTG +L++ A FGA G
Sbjct: 183 IESYSVKKRHFIGNTSMDAGLSFIMANHGKVKENDIVFDPFVGTGGLLIACAHFGAYVYG 242
Query: 800 ADIDIRVV----------RDGRGPDCNL 853
DID V + RGPD N+
Sbjct: 243 TDIDYNTVHGLGKATRKNQKWRGPDENI 270
>sp|Q05B63|TRM11_BOVIN tRNA guanosine-2'-O-methyltransferase TRM11 homolog
OS=Bos taurus GN=TRMT11 PE=2 SV=1
Length = 460
Score = 206 bits (522), Expect = 3e-052
Identities = 107/268 (39%), Positives = 166/268 (61%), Gaps = 17/268 (6%)
Frame = +2
Query: 80 FLCVFYHRLLDFRKPEVEALAELFGEDESLLQWRLPEHHHNDTPFHFVHLSSEEIAQNIA 259
+L + L+FR PE+++L LFG Q+ + + +PF + + SE+IA+N+
Sbjct: 10 YLLLMAQEHLEFRLPEIKSLLSLFGG-----QFISSQETYGKSPFWILSIPSEDIARNLM 64
Query: 260 KRSILVKGMYELWGEGASYEELKDSIQSFPDSRKLPFLDSDSTFRISVETFGKALTFDEQ 439
KR++ K ++ELWG G EEL S++++P + +PFL SDST++I + TF K LT +E+
Sbjct: 65 KRTVCAKSIFELWGHGKCPEELYSSLKNYPVEKMVPFLHSDSTYKIKIHTFNKTLTQEEK 124
Query: 440 RERINSLTYIPFEGKVNLKKPDHKFFIIEMDESEENNGLQPILQRRIFFGREVGFADRKL 619
+RI++L ++PFEGKVNLKKP H F I+E D + N + P I+FGR + R+L
Sbjct: 125 VKRIDALEFLPFEGKVNLKKPQHVFSILE-DYGLDPNHI-PENPHNIYFGRWIADGQREL 182
Query: 620 LPTFQLKSRTYLGPTAMDAEMAFLMANQAKATSGKLVYDPFVGTGSILVSAARFGAMTMG 799
+ ++ +K R ++G T+MDA ++F+MAN K +V+DPFVGTG +L+++A FGA G
Sbjct: 183 IESYSVKKRHFIGNTSMDAGLSFIMANHGKVKKNDIVFDPFVGTGGLLIASAHFGAYVYG 242
Query: 800 ADIDIRVV----------RDGRGPDCNL 853
DID V + RGPD N+
Sbjct: 243 TDIDYNTVHGLGKASRKNQKWRGPDENI 270
>sp|Q5R962|TRM11_PONAB tRNA guanosine-2'-O-methyltransferase TRM11 homolog
OS=Pongo abelii GN=TRMT11 PE=2 SV=1
Length = 463
Score = 206 bits (522), Expect = 3e-052
Identities = 107/268 (39%), Positives = 165/268 (61%), Gaps = 17/268 (6%)
Frame = +2
Query: 80 FLCVFYHRLLDFRKPEVEALAELFGEDESLLQWRLPEHHHNDTPFHFVHLSSEEIAQNIA 259
+L + L+FR PE+++L LFG Q+ + +PF + + SE+IA+N+
Sbjct: 10 YLLLMAQEHLEFRLPEIKSLLSLFGG-----QFGSSQETFGKSPFWILSIPSEDIARNLM 64
Query: 260 KRSILVKGMYELWGEGASYEELKDSIQSFPDSRKLPFLDSDSTFRISVETFGKALTFDEQ 439
KR++ K ++ELWG G S EEL S++++P + +PFL SDST++I + TF K LT +E+
Sbjct: 65 KRTVCAKSIFELWGHGQSPEELYSSLKNYPVEKMVPFLHSDSTYKIKIHTFNKTLTQEEK 124
Query: 440 RERINSLTYIPFEGKVNLKKPDHKFFIIEMDESEENNGLQPILQRRIFFGREVGFADRKL 619
+RI++L ++PFEGKVNLKKP H F ++E D + N + P I+FGR + R+L
Sbjct: 125 IKRIDALEFLPFEGKVNLKKPQHVFSVLE-DYGLDPNCI-PENPHNIYFGRWIADGQREL 182
Query: 620 LPTFQLKSRTYLGPTAMDAEMAFLMANQAKATSGKLVYDPFVGTGSILVSAARFGAMTMG 799
+ ++ +K R ++G T+MDA ++F+MAN K +V+DPFVGTG +L++ A FGA G
Sbjct: 183 IESYSVKKRHFIGNTSMDAGLSFIMANHGKVKENDIVFDPFVGTGGLLIACAHFGAYVYG 242
Query: 800 ADIDIRVV----------RDGRGPDCNL 853
DID V + RGPD N+
Sbjct: 243 TDIDYNTVHGLGKATRKNQKWRGPDENI 270
>sp|Q9CWH5|TRM11_MOUSE tRNA guanosine-2'-O-methyltransferase TRM11 homolog
OS=Mus musculus GN=Trmt11 PE=2 SV=1
Length = 460
Score = 205 bits (520), Expect = 5e-052
Identities = 106/268 (39%), Positives = 167/268 (62%), Gaps = 17/268 (6%)
Frame = +2
Query: 80 FLCVFYHRLLDFRKPEVEALAELFGEDESLLQWRLPEHHHNDTPFHFVHLSSEEIAQNIA 259
+L + L+FR PE+++L + G Q+ + + +PF +++ SE+IA+N+
Sbjct: 10 YLLLMAQEHLEFRLPEIKSLLSVIGG-----QFTNSQETYGKSPFWILNIPSEDIARNLM 64
Query: 260 KRSILVKGMYELWGEGASYEELKDSIQSFPDSRKLPFLDSDSTFRISVETFGKALTFDEQ 439
KR++ K ++ELWG G S EEL S++S+P + +P+L SDST++I + TF K LT +E+
Sbjct: 65 KRTVCAKSIFELWGHGKSPEELYTSLKSYPVEKMVPYLHSDSTYKIKIHTFNKTLTQEEK 124
Query: 440 RERINSLTYIPFEGKVNLKKPDHKFFIIEMDESEENNGLQPILQRRIFFGREVGFADRKL 619
+RI++L ++PF+GKVNLKKP H F I+E D + N + P I+FGR + R+L
Sbjct: 125 VKRIDALEFLPFQGKVNLKKPQHVFSILE-DYGLDPNSI-PKDPHNIYFGRWIADGQREL 182
Query: 620 LPTFQLKSRTYLGPTAMDAEMAFLMANQAKATSGKLVYDPFVGTGSILVSAARFGAMTMG 799
+ ++ +K R ++G T+MDA ++F+M N AK LV+DPFVGTG +L+++A FGA G
Sbjct: 183 IESYSVKKRHFIGNTSMDAGLSFIMTNHAKVKENDLVFDPFVGTGGLLIASAHFGAYVCG 242
Query: 800 ADIDIRVV----------RDGRGPDCNL 853
DID V + RGPD N+
Sbjct: 243 TDIDYNTVHGLGKASRKNQKWRGPDENI 270
>sp|Q6NS23|TRM11_XENLA tRNA guanosine-2'-O-methyltransferase TRM11 homolog
OS=Xenopus laevis GN=trmt11 PE=2 SV=1
Length = 478
Score = 189 bits (478), Expect = 3e-047
Identities = 98/268 (36%), Positives = 161/268 (60%), Gaps = 17/268 (6%)
Frame = +2
Query: 80 FLCVFYHRLLDFRKPEVEALAELFGEDESLLQWRLPEHHHNDTPFHFVHLSSEEIAQNIA 259
+L + +FR PE+++L L+G + LQ H +PF ++L SEE+A+ +
Sbjct: 14 YLLLLAQENCEFRLPEIKSLLSLYGGHFNNLQ-----DEHGKSPFCILNLPSEEMARKLM 68
Query: 260 KRSILVKGMYELWGEGASYEELKDSIQSFPDSRKLPFLDSDSTFRISVETFGKALTFDEQ 439
KR++ K ++ELWG G ++ E + S+ S+P + +L +ST++I + +F K LT E+
Sbjct: 69 KRTVCAKSVFELWGHGKTFMEFQQSVLSYPLENMMSYLQPNSTYKIIIHSFNKTLTQKEK 128
Query: 440 RERINSLTYIPFEGKVNLKKPDHKFFIIEMDESEENNGLQPILQRRIFFGREVGFADRKL 619
E+IN++ +IPF+GKVNL+ ++ F+++E S+ N P IFFGR + R+L
Sbjct: 129 LEKINTMEFIPFQGKVNLQNAENIFYLLEDYGSDPNKA--PNEPFEIFFGRWIADGQREL 186
Query: 620 LPTFQLKSRTYLGPTAMDAEMAFLMANQAKATSGKLVYDPFVGTGSILVSAARFGAMTMG 799
+ ++ +K R ++G T+MDA ++F+MAN A+ +V+DPFVGTG +LVS+A FGA G
Sbjct: 187 INSYSVKKRHFIGNTSMDAGLSFIMANHARVKPNDVVFDPFVGTGGLLVSSAHFGAYVCG 246
Query: 800 ADIDIRVV----------RDGRGPDCNL 853
+ID V + RGPD N+
Sbjct: 247 TEIDYNTVHGLGKATRMNQKWRGPDENI 274
>sp|Q6YJI5|TRM11_CHICK tRNA guanosine-2'-O-methyltransferase TRM11 homolog
OS=Gallus gallus GN=TRMT11 PE=2 SV=1
Length = 461
Score = 186 bits (471), Expect = 2e-046
Identities = 97/268 (36%), Positives = 160/268 (59%), Gaps = 17/268 (6%)
Frame = +2
Query: 80 FLCVFYHRLLDFRKPEVEALAELFGEDESLLQWRLPEHHHNDTPFHFVHLSSEEIAQNIA 259
+L + L+FR PE+ +L L G Q+ + ++PF +++ SEE+A+ +
Sbjct: 11 YLLLLAQEHLEFRLPEITSLLSLCGG-----QFSSQQEVCVNSPFWILNIPSEEMARGLM 65
Query: 260 KRSILVKGMYELWGEGASYEELKDSIQSFPDSRKLPFLDSDSTFRISVETFGKALTFDEQ 439
+R++ K ++ELWG G S EL S++++P + LP+L DST++I + TF K LT ++
Sbjct: 66 RRTVCAKSIFELWGHGRSAGELYASLKNYPTDKMLPYLQPDSTYKIHIHTFNKTLTQAQK 125
Query: 440 RERINSLTYIPFEGKVNLKKPDHKFFIIEMDESEENNGLQPILQRRIFFGREVGFADRKL 619
++I++L ++PF GKVNLK P+H F+I+E + NN P ++FGR + R+L
Sbjct: 126 IKKIDALEFLPFSGKVNLKNPEHIFWILEDYGMDPNN--VPEEPFDLYFGRWIADGQREL 183
Query: 620 LPTFQLKSRTYLGPTAMDAEMAFLMANQAKATSGKLVYDPFVGTGSILVSAARFGAMTMG 799
+ ++ +K R ++G T+MDA ++F+MAN + +VYDPFVGTG +L+S+A FGA G
Sbjct: 184 IESYSIKKRHFIGNTSMDACLSFIMANHGRVKPNDIVYDPFVGTGGLLISSAHFGAYVCG 243
Query: 800 ADIDIRVV----------RDGRGPDCNL 853
ID + + RGPD N+
Sbjct: 244 TGIDYNTIHGLGKASRKNQKWRGPDENI 271
>sp|Q12463|TRM11_YEAST tRNA guanosine-2'-O-methyltransferase TRM11
OS=Saccharomyces cerevisiae GN=TRM11 PE=1 SV=1
Length = 433
Score = 158 bits (399), Expect = 5e-038
Identities = 93/254 (36%), Positives = 149/254 (58%), Gaps = 18/254 (7%)
Frame = +2
Query: 107 LDFRKPEVEALAELFGEDESLLQWRLPEHHHNDTPFHFVHLSSEEIAQNIAKRSILVKGM 286
L+FR+ E+E+LA+L+ Q + ++PF V L +++ A++ KRSIL +G+
Sbjct: 13 LNFRRAELESLADLYNLSIDFSQ------YDANSPFFIVELENDQQAKDWIKRSILTRGI 66
Query: 287 YELWGEGASYEELKDSIQ---SFPDSRKLPFLDSDSTFRISVETFGKALTFDEQRERINS 457
YE WG+G + +EL IQ +F +L F STF+ E + K + ++ E+I +
Sbjct: 67 YEYWGQGTTLDELHKDIQRQSNFEQDLQLKF--KHSTFKFEFECY-KGNSKAKRVEQIET 123
Query: 458 LTYIPFEGKVNLKKPDHKFFIIE--MDESEENNGLQPILQRRIFFGREVGFADRKLLPTF 631
Y+ FEGK+++K P F +IE SE G P RI+FGR+V ++R + +
Sbjct: 124 FRYLGFEGKIDMKHPQEVFTVIEEYTPISENVGGKTP---TRIYFGRQVQMSNRSAMEKY 180
Query: 632 QLKSRTYLGPTAMDAEMAFLMANQAKATSGKLVYDPFVGTGSILVSAARFGAMTMGADID 811
LK R Y G T+ +AE++ + AN A+ G ++YDPF GTGS LV+ FG++ +G+DID
Sbjct: 181 DLKKRPYKGTTSFEAELSLVSANIAQVKPGTIMYDPFAGTGSFLVAGGHFGSLVIGSDID 240
Query: 812 IRVVRDGRGPDCNL 853
R++R G+G N+
Sbjct: 241 GRMIR-GKGAQVNI 253
>sp|O94636|TRM11_SCHPO tRNA guanosine-2'-O-methyltransferase trm11
OS=Schizosaccharomyces pombe GN=trm11 PE=2 SV=2
Length = 469
Score = 139 bits (349), Expect = 3e-032
Identities = 81/229 (35%), Positives = 125/229 (54%), Gaps = 10/229 (4%)
Frame = +2
Query: 185 PEHHHNDTPFHFVHLSSEEIAQNIAKRSILVKGMYELWGEGASYEELKDSIQSFPDSRKL 364
P PF ++S E A+ +RSI KG+YE++ G S+ L + ++ +
Sbjct: 68 PNDATTQNPFMLAVVNSNEDARRWIRRSIFCKGIYEIYCIGDSFTRLHEKMKELNPAPWD 127
Query: 365 PFLDSDSTFRISVETFGKALTFDEQRERINSLTYIPFEGKVNLKKPDHKFFIIEMDESEE 544
F +S+++ + ETFG T EQ I+ Y+ +G V++ P H F ++ E+
Sbjct: 128 SF-KHNSSYKFTFETFGTRRTMKEQLSIISDFEYMQLQGPVSMHNPQHVFTVL---ENRR 183
Query: 545 NNGLQPILQRRIFFGREVGFADRKLLPTFQLKSRTYLGPTAMDAEMAFLMANQAKATSGK 724
NN P +++FG G R + TF LK R+Y+G T+ DAE++ + A A A GK
Sbjct: 184 NNVEGP----KVYFGHWCGSGSRDAIDTFDLKQRSYIGITSFDAELSLVTAQMAMAAPGK 239
Query: 725 LVYDPFVGTGSILVSAARFGAMTMGADIDIRVVR--DGRGPDCNLEQFQ 865
L+YDPFVGTGS L + + FGA T+G+DID R +R +GR N Q++
Sbjct: 240 LIYDPFVGTGSFLYTCSFFGAHTLGSDIDGRQMRGKNGRSIKSNFRQYK 288
>sp|Q54QA6|TRM11_DICDI tRNA guanosine-2'-O-methyltransferase TRM11 homolog
OS=Dictyostelium discoideum GN=trmt11 PE=3 SV=1
Length = 507
Score = 90 bits (222), Expect = 2e-017
Identities = 48/120 (40%), Positives = 69/120 (57%), Gaps = 5/120 (4%)
Frame = +2
Query: 506 HKFFIIEMDESEENNGLQ---PILQRRIFFGREVGFADRKLLPTFQLKSRTYLGPTAMDA 676
H + I D E GL +L R+++FG+ + +R + + L R YLG T+MD
Sbjct: 157 HILWYILTDFGVERQGLVKDFTLLPRKVYFGQRIAKGNRDDIIKYNLSDRKYLGTTSMDP 216
Query: 677 EMAFLMANQAKATSGKLVYDPFVGTGSILVSAARFGAMTMGADIDIRVVRDGRGPDCNLE 856
E++ + AN G V DPFVGTGS ++ A+ FGA T+G DIDI+ +R + DCNLE
Sbjct: 217 ELSLVSANMGLVKKGHFVLDPFVGTGSFILVASHFGAQTVGCDIDIKAMR--KEEDCNLE 274
>sp|O26820|Y724_METTH Putative RNA methyltransferase MTH_724 OS=Methanobacterium
thermoautotrophicum GN=MTH_724 PE=3 SV=1
Length = 336
Score = 51 bits (121), Expect = 8e-006
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Frame = +2
Query: 554 LQPIL-QRRIFFGREVGFADRKLLPTFQLKSRTYLGPTAMDAEMAFLMANQAKATSGKLV 730
++P+L R R + ++ + R + P +M ++A M N + +G +
Sbjct: 132 IRPVLINDRFILTRRLAVISKEHFNQARPHKRPFFYPGSMSPKLARCMVNLSGVKAGDRI 191
Query: 731 YDPFVGTGSILVSAARFGAMTMGADIDIRVVRDGR 835
DPF GTG IL+ A G +GADID R+V R
Sbjct: 192 LDPFCGTGGILIEAGLMGVRVVGADIDWRMVEGTR 226
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,894,514,945
Number of Sequences: 518415
Number of Extensions: 45894514945
Number of Successful Extensions: 338263929
Number of sequences better than 0.0: 0
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