BLASTX 7.6.2
Query= UN11406 /QuerySize=1092
(1091 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7T339|CHMP5_DANRE Charged multivesicular body protein 5 OS=D... 96 4e-019
sp|Q9NZZ3|CHMP5_HUMAN Charged multivesicular body protein 5 OS=H... 94 2e-018
sp|Q9D7S9|CHMP5_MOUSE Charged multivesicular body protein 5 OS=M... 94 2e-018
sp|Q5RBR3|CHMP5_PONAB Charged multivesicular body protein 5 OS=P... 94 2e-018
sp|Q4QQV8|CHMP5_RAT Charged multivesicular body protein 5 OS=Rat... 94 2e-018
sp|Q5FW29|CHMP5_XENTR Charged multivesicular body protein 5 OS=X... 93 3e-018
sp|Q6DD52|CHMP5_XENLA Charged multivesicular body protein 5 OS=X... 92 8e-018
sp|Q54JK4|CHMP5_DICDI Charged multivesicular body protein 5 OS=D... 89 6e-017
sp|Q9VVI9|CHMP5_DROME Charged multivesicular body protein 5 OS=D... 80 2e-014
sp|O74422|YQ56_SCHPO Uncharacterized protein C162.06c OS=Schizos... 77 1e-013
sp|Q5KL29|SNF7_CRYNE Vacuolar-sorting protein SNF7 OS=Cryptococc... 56 4e-007
sp|Q03390|VPS60_YEAST Vacuolar protein-sorting-associated protei... 56 4e-007
>sp|Q7T339|CHMP5_DANRE Charged multivesicular body protein 5 OS=Danio rerio
GN=chmp5 PE=2 SV=1
Length = 220
Score = 96 bits (237), Expect = 4e-019
Identities = 44/99 (44%), Positives = 70/99 (70%)
Frame = +3
Query: 273 INKRGESVEDKVKRLDAELCKYKDQIKRTRPGPAQETIKARAMRVLKQKKMYEGQRDMLY 452
++ R ESV+ K+ RLDAEL KYKDQ+K+ R GP++ +K +AMRVLKQK+MYEGQRD L
Sbjct: 24 VDSRAESVDKKIARLDAELMKYKDQMKKMRDGPSKNMVKQKAMRVLKQKRMYEGQRDQLM 83
Query: 453 NQTFNLDQVPFAAEEPQRRSTNYDSVEICQQGVERNDEN 569
Q+FN++Q + + + T ++++I + +++ +N
Sbjct: 84 QQSFNMEQANYTIQTLKDTKTTVEAMKIGAKEMKKAYKN 122
>sp|Q9NZZ3|CHMP5_HUMAN Charged multivesicular body protein 5 OS=Homo sapiens
GN=CHMP5 PE=1 SV=1
Length = 219
Score = 94 bits (231), Expect = 2e-018
Identities = 42/88 (47%), Positives = 63/88 (71%)
Frame = +3
Query: 273 INKRGESVEDKVKRLDAELCKYKDQIKRTRPGPAQETIKARAMRVLKQKKMYEGQRDMLY 452
++ R ES++ K+ RLDAEL KYKDQIK+ R GPA+ +K +A+RVLKQK+MYE QRD L
Sbjct: 24 VDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLA 83
Query: 453 NQTFNLDQVPFAAEEPQRRSTNYDSVEI 536
Q+FN++Q + + + T D++++
Sbjct: 84 QQSFNMEQANYTIQSLKDTKTTVDAMKL 111
Score = 80 bits (196), Expect = 2e-014
Identities = 47/104 (45%), Positives = 69/104 (66%), Gaps = 6/104 (5%)
Frame = +1
Query: 490 LKSLKDAQQTMTALKSANKELKGMMRTVKIQDIDNLQDEMMDLMDVSSEIQDSLGRSYNV 669
++SLKD + T+ A+K KE+K + VKI I++LQD++ D+M+ ++EIQ++L RSY
Sbjct: 96 IQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGT 155
Query: 670 PDDIDEDDLMGELDALEADMGNETEADGVPSYL-QADKEPDLDE 798
P ++DEDDL ELDAL G+E AD SYL +A P + E
Sbjct: 156 P-ELDEDDLEAELDAL----GDELLADEDSSYLDEAASAPAIPE 194
>sp|Q9D7S9|CHMP5_MOUSE Charged multivesicular body protein 5 OS=Mus musculus
GN=Chmp5 PE=2 SV=1
Length = 219
Score = 94 bits (231), Expect = 2e-018
Identities = 42/88 (47%), Positives = 63/88 (71%)
Frame = +3
Query: 273 INKRGESVEDKVKRLDAELCKYKDQIKRTRPGPAQETIKARAMRVLKQKKMYEGQRDMLY 452
++ R ES++ K+ RLDAEL KYKDQIK+ R GPA+ +K +A+RVLKQK+MYE QRD L
Sbjct: 24 VDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLA 83
Query: 453 NQTFNLDQVPFAAEEPQRRSTNYDSVEI 536
Q+FN++Q + + + T D++++
Sbjct: 84 QQSFNMEQANYTIQSLKDTKTTVDAMKL 111
Score = 82 bits (202), Expect = 5e-015
Identities = 48/104 (46%), Positives = 70/104 (67%), Gaps = 6/104 (5%)
Frame = +1
Query: 490 LKSLKDAQQTMTALKSANKELKGMMRTVKIQDIDNLQDEMMDLMDVSSEIQDSLGRSYNV 669
++SLKD + T+ A+K KE+K + VKI I++LQD++ D+M+ ++EIQ++LGRSY
Sbjct: 96 IQSLKDTKTTVDAMKLGVKEMKKAYKEVKIDQIEDLQDQLEDMMEDANEIQEALGRSYGT 155
Query: 670 PDDIDEDDLMGELDALEADMGNETEADGVPSYL-QADKEPDLDE 798
P ++DEDDL ELDAL G+E AD SYL +A P + E
Sbjct: 156 P-ELDEDDLEAELDAL----GDELLADEDSSYLDEAASAPAIPE 194
>sp|Q5RBR3|CHMP5_PONAB Charged multivesicular body protein 5 OS=Pongo abelii
GN=CHMP5 PE=2 SV=1
Length = 219
Score = 94 bits (231), Expect = 2e-018
Identities = 42/88 (47%), Positives = 63/88 (71%)
Frame = +3
Query: 273 INKRGESVEDKVKRLDAELCKYKDQIKRTRPGPAQETIKARAMRVLKQKKMYEGQRDMLY 452
++ R ES++ K+ RLDAEL KYKDQIK+ R GPA+ +K +A+RVLKQK+MYE QRD L
Sbjct: 24 VDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLA 83
Query: 453 NQTFNLDQVPFAAEEPQRRSTNYDSVEI 536
Q+FN++Q + + + T D++++
Sbjct: 84 QQSFNMEQANYTIQSLKDTKTTVDAMKL 111
Score = 80 bits (196), Expect = 2e-014
Identities = 47/104 (45%), Positives = 69/104 (66%), Gaps = 6/104 (5%)
Frame = +1
Query: 490 LKSLKDAQQTMTALKSANKELKGMMRTVKIQDIDNLQDEMMDLMDVSSEIQDSLGRSYNV 669
++SLKD + T+ A+K KE+K + VKI I++LQD++ D+M+ ++EIQ++L RSY
Sbjct: 96 IQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGT 155
Query: 670 PDDIDEDDLMGELDALEADMGNETEADGVPSYL-QADKEPDLDE 798
P ++DEDDL ELDAL G+E AD SYL +A P + E
Sbjct: 156 P-ELDEDDLEAELDAL----GDELLADEDSSYLDEAASAPAIPE 194
>sp|Q4QQV8|CHMP5_RAT Charged multivesicular body protein 5 OS=Rattus norvegicus
GN=Chmp5 PE=2 SV=1
Length = 219
Score = 94 bits (231), Expect = 2e-018
Identities = 42/88 (47%), Positives = 63/88 (71%)
Frame = +3
Query: 273 INKRGESVEDKVKRLDAELCKYKDQIKRTRPGPAQETIKARAMRVLKQKKMYEGQRDMLY 452
++ R ES++ K+ RLDAEL KYKDQIK+ R GPA+ +K +A+RVLKQK+MYE QRD L
Sbjct: 24 VDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLA 83
Query: 453 NQTFNLDQVPFAAEEPQRRSTNYDSVEI 536
Q+FN++Q + + + T D++++
Sbjct: 84 QQSFNMEQANYTIQSLKDTKTTVDAMKL 111
Score = 82 bits (202), Expect = 5e-015
Identities = 48/104 (46%), Positives = 70/104 (67%), Gaps = 6/104 (5%)
Frame = +1
Query: 490 LKSLKDAQQTMTALKSANKELKGMMRTVKIQDIDNLQDEMMDLMDVSSEIQDSLGRSYNV 669
++SLKD + T+ A+K KE+K + VKI I++LQD++ D+M+ ++EIQ++LGRSY
Sbjct: 96 IQSLKDTKTTVDAMKLGVKEMKKAYKEVKIDQIEDLQDQLEDMMEDANEIQEALGRSYGT 155
Query: 670 PDDIDEDDLMGELDALEADMGNETEADGVPSYL-QADKEPDLDE 798
P ++DEDDL ELDAL G+E AD SYL +A P + E
Sbjct: 156 P-ELDEDDLEAELDAL----GDELLADEDSSYLDEAASAPAIPE 194
>sp|Q5FW29|CHMP5_XENTR Charged multivesicular body protein 5 OS=Xenopus
tropicalis GN=chmp5 PE=2 SV=1
Length = 219
Score = 93 bits (230), Expect = 3e-018
Identities = 41/88 (46%), Positives = 64/88 (72%)
Frame = +3
Query: 273 INKRGESVEDKVKRLDAELCKYKDQIKRTRPGPAQETIKARAMRVLKQKKMYEGQRDMLY 452
++ R ES++ K+ RLDAEL KYKDQ+K+ R GP++ +K +A+RVLKQK+MYE QRD L
Sbjct: 24 VDSRSESIDKKISRLDAELVKYKDQMKKMREGPSKNMVKQKALRVLKQKRMYEQQRDNLN 83
Query: 453 NQTFNLDQVPFAAEEPQRRSTNYDSVEI 536
Q+FN++Q +A + + T D++++
Sbjct: 84 QQSFNMEQTNYAIQSLKDTKTTVDAMKV 111
Score = 80 bits (195), Expect = 3e-014
Identities = 47/104 (45%), Positives = 68/104 (65%), Gaps = 6/104 (5%)
Frame = +1
Query: 490 LKSLKDAQQTMTALKSANKELKGMMRTVKIQDIDNLQDEMMDLMDVSSEIQDSLGRSYNV 669
++SLKD + T+ A+K KE+K + VKI I++LQD++ D+M+ ++EIQ++L RSY
Sbjct: 96 IQSLKDTKTTVDAMKVGAKEMKKAYKQVKIDQIEDLQDQLEDMMENANEIQEALSRSYGT 155
Query: 670 PDDIDEDDLMGELDALEADMGNETEADGVPSYL-QADKEPDLDE 798
P +IDEDDL ELDAL G+E D SYL +A P + E
Sbjct: 156 P-EIDEDDLEAELDAL----GDELLLDDDTSYLDEAASAPAIPE 194
>sp|Q6DD52|CHMP5_XENLA Charged multivesicular body protein 5 OS=Xenopus laevis
GN=chmp5 PE=2 SV=1
Length = 219
Score = 92 bits (226), Expect = 8e-018
Identities = 41/88 (46%), Positives = 63/88 (71%)
Frame = +3
Query: 273 INKRGESVEDKVKRLDAELCKYKDQIKRTRPGPAQETIKARAMRVLKQKKMYEGQRDMLY 452
++ R ES+E K+ RLDAEL KYKDQ+K+ R GP++ +K +A+RVLKQK+MYE QRD L
Sbjct: 24 VDGRAESIEKKISRLDAELIKYKDQMKKMREGPSKNMVKQKALRVLKQKRMYEQQRDNLN 83
Query: 453 NQTFNLDQVPFAAEEPQRRSTNYDSVEI 536
Q+FN++Q + + + T D++++
Sbjct: 84 QQSFNMEQANYTIQTLKDTKTTVDAMKV 111
>sp|Q54JK4|CHMP5_DICDI Charged multivesicular body protein 5 OS=Dictyostelium
discoideum GN=chmp5 PE=3 SV=1
Length = 215
Score = 89 bits (218), Expect = 6e-017
Identities = 43/102 (42%), Positives = 67/102 (65%), Gaps = 5/102 (4%)
Frame = +1
Query: 493 KSLKDAQQTMTALKSANKELKGMMRTVKIQDIDNLQDEMMDLMDVSSEIQDSLGRSYNVP 672
+S++D T++A+K K++K ++ +KI+D+D++QDEM DL+D ++EIQ+SLGR+Y P
Sbjct: 96 ESMRDTITTVSAMKQGAKDMKTQLKHIKIEDVDDMQDEMQDLLDYNNEIQESLGRAYQTP 155
Query: 673 DDIDEDDLMGELDALEADMGNETEAD-GVPSYLQADKEPDLD 795
D +DE +L EL MG E E + +PSYL P D
Sbjct: 156 DTLDESELEAEL----MSMGEELELEASMPSYLMTPSVPTTD 193
Score = 79 bits (194), Expect = 4e-014
Identities = 39/88 (44%), Positives = 57/88 (64%)
Frame = +3
Query: 270 QINKRGESVEDKVKRLDAELCKYKDQIKRTRPGPAQETIKARAMRVLKQKKMYEGQRDML 449
+I R +++K+ L+ EL Y QIK TRPGPAQ IK +A+RVL+QKKMYE QRD +
Sbjct: 22 RIGGRMGQMDEKINGLNQELLAYDKQIKATRPGPAQNAIKQKAIRVLQQKKMYERQRDQM 81
Query: 450 YNQTFNLDQVPFAAEEPQRRSTNYDSVE 533
+ +FN++Q FA E + T +++
Sbjct: 82 ASTSFNMEQTKFATESMRDTITTVSAMK 109
>sp|Q9VVI9|CHMP5_DROME Charged multivesicular body protein 5 OS=Drosophila
melanogaster GN=CG6259 PE=1 SV=2
Length = 226
Score = 80 bits (196), Expect = 2e-014
Identities = 34/74 (45%), Positives = 56/74 (75%)
Frame = +3
Query: 273 INKRGESVEDKVKRLDAELCKYKDQIKRTRPGPAQETIKARAMRVLKQKKMYEGQRDMLY 452
++ R ++E+K+ L+AEL KY++Q+ + R GPA+ ++K +A+RVLKQKK YE Q + L
Sbjct: 24 VDARATNIEEKISNLEAELRKYREQMSKMREGPAKNSVKQKALRVLKQKKAYEQQAESLR 83
Query: 453 NQTFNLDQVPFAAE 494
NQ+FN++Q +AA+
Sbjct: 84 NQSFNMEQANYAAQ 97
Score = 77 bits (187), Expect = 3e-013
Identities = 38/92 (41%), Positives = 61/92 (66%), Gaps = 5/92 (5%)
Frame = +1
Query: 493 KSLKDAQQTMTALKSANKELKGMMRTVKIQDIDNLQDEMMDLMDVSSEIQDSLGRSYNVP 672
+SLKD Q T+ A+K K++K + + I I+++QD+M D+ + + E+Q++LGR+Y +P
Sbjct: 97 QSLKDTQATVAAMKDGVKQMKTEYKKINIDQIEDIQDDMADMFEQADEVQEALGRTYGMP 156
Query: 673 DDIDEDDLMGELDALEADMGNETEADGVPSYL 768
++D+DDL ELDAL G+E D SYL
Sbjct: 157 -EVDDDDLQAELDAL----GDEIALDDDTSYL 183
>sp|O74422|YQ56_SCHPO Uncharacterized protein C162.06c OS=Schizosaccharomyces
pombe GN=SPCC162.06c PE=2 SV=1
Length = 210
Score = 77 bits (189), Expect = 1e-013
Identities = 36/99 (36%), Positives = 59/99 (59%)
Frame = +3
Query: 273 INKRGESVEDKVKRLDAELCKYKDQIKRTRPGPAQETIKARAMRVLKQKKMYEGQRDMLY 452
++KR +SVE K+ +LDA+L ++ +I TRPGP Q +K RAM VL+QKK+YE Q L
Sbjct: 24 LDKRSDSVEVKIAKLDAQLSVFQQKIANTRPGPGQTALKQRAMNVLRQKKIYESQLQQLQ 83
Query: 453 NQTFNLDQVPFAAEEPQRRSTNYDSVEICQQGVERNDEN 569
Q+FN++Q E + +++ + ++ +N
Sbjct: 84 QQSFNMEQAAMTTESLKNTMATVQTMQETARQLKSQSKN 122
Score = 64 bits (153), Expect = 2e-009
Identities = 40/113 (35%), Positives = 71/113 (62%), Gaps = 9/113 (7%)
Frame = +1
Query: 493 KSLKDAQQTMTALKSANKELKGMMRTVKIQDIDNLQDEMMDLMDVSSEIQDSLGRSYNVP 672
+SLK+ T+ ++ ++LK + V I+ I+ LQDE+ D MD + E+ + LG+ N+
Sbjct: 97 ESLKNTMATVQTMQETARQLKSQSKNVSIEKIEKLQDEIQDYMDAAGELNEVLGQ--NMT 154
Query: 673 D-DIDEDDLMGELDALEAD---MGNETEADGVPSYLQADKE-PD-LDEELDLP 813
D ++DE++L EL+AL+ + +G+++ A+ PSYL E P+ +DEE+ P
Sbjct: 155 DINVDEEELDAELEALQQESSWLGDQSTAE-KPSYLMPSNELPNFVDEEVAEP 206
>sp|Q5KL29|SNF7_CRYNE Vacuolar-sorting protein SNF7 OS=Cryptococcus neoformans
GN=SNF7 PE=3 SV=1
Length = 220
Score = 56 bits (134), Expect = 4e-007
Identities = 33/105 (31%), Positives = 59/105 (56%), Gaps = 2/105 (1%)
Frame = +1
Query: 466 TLIKFLSLLKSLKDAQQTMTALKSANKELKGMMRTVKIQDIDNLQDEMMDLMDVSSEIQD 645
TL ++ ++S +TM A+K LKG+ + + +D D++ + MD++++I D
Sbjct: 84 TLETQVNAIESANLNAETMVAMKKGADALKGIHSNLTAEGVDATMDKIREQMDLTNDISD 143
Query: 646 SLGRSYNVPDDIDEDDLMGELDALEADMGNE--TEADGVPSYLQA 774
++ + +DEDDL EL+ALE + ++ AD VPS+L A
Sbjct: 144 AISNPVGMGIVLDEDDLKEELEALEQEQLDDRLAGADRVPSHLPA 188
>sp|Q03390|VPS60_YEAST Vacuolar protein-sorting-associated protein 60
OS=Saccharomyces cerevisiae GN=VPS60 PE=1 SV=2
Length = 229
Score = 56 bits (134), Expect = 4e-007
Identities = 39/119 (32%), Positives = 61/119 (51%), Gaps = 19/119 (15%)
Frame = +1
Query: 496 SLKDAQQTMTALKSANKELKGMMRTVKIQDIDNLQDEMMDLMDVSSEIQDSLGRSYNVP- 672
+L++ T+ ALK N +K + I + ++QDEM+DL++ E+Q+ L + N
Sbjct: 103 NLQNTMITINALKQTNNAMKAQYGKINIDKLQDMQDEMLDLIEQGDELQEVLAMNNNSGE 162
Query: 673 -DDIDEDDLMGELDAL----------EADMGNETEADGVPSYLQADKEPD--LDEELDL 810
DDI + +L ELDAL E +GN+ +PSYL P +DEE +L
Sbjct: 163 LDDISDAELDAELDALAQEDFTLPTSENSLGND-----MPSYLLGANAPPAFIDEEPNL 216
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,894,514,945
Number of Sequences: 518415
Number of Extensions: 45894514945
Number of Successful Extensions: 338263929
Number of sequences better than 0.0: 0
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