BLASTX 7.6.2
Query= UN11439 /QuerySize=1117
(1116 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q96C23|GALM_HUMAN Aldose 1-epimerase OS=Homo sapiens GN=GALM ... 174 9e-043
sp|Q8K157|GALM_MOUSE Aldose 1-epimerase OS=Mus musculus GN=Galm ... 174 1e-042
sp|Q5R8U1|GALM_PONAB Aldose 1-epimerase OS=Pongo abelii GN=GALM ... 174 1e-042
sp|Q5EA79|GALM_BOVIN Aldose 1-epimerase OS=Bos taurus GN=GALM PE... 172 5e-042
sp|Q66HG4|GALM_RAT Aldose 1-epimerase OS=Rattus norvegicus GN=Ga... 171 1e-041
sp|Q9GKX6|GALM_PIG Aldose 1-epimerase OS=Sus scrofa GN=GALM PE=2... 168 7e-041
sp|P05149|GALM_ACICA Aldose 1-epimerase OS=Acinetobacter calcoac... 151 1e-035
sp|P04397|GAL10_YEAST Bifunctional protein GAL10 OS=Saccharomyce... 67 2e-010
sp|P31765|GALM_HAEIN Aldose 1-epimerase OS=Haemophilus influenza... 53 4e-006
>sp|Q96C23|GALM_HUMAN Aldose 1-epimerase OS=Homo sapiens GN=GALM PE=1 SV=1
Length = 342
Score = 174 bits (441), Expect = 9e-043
Identities = 91/210 (43%), Positives = 128/210 (60%), Gaps = 6/210 (2%)
Frame = +3
Query: 414 DGEEGFPGNVTVMVTYMLIGENELALKMEAKPLDKPTPINLALHTYWNLHGHNSGDILSH 593
DGEEG+PG + V VTY L G EL + A+ + TP+NL H+Y+NL G S +I H
Sbjct: 135 DGEEGYPGELKVWVTYTLDG-GELIVNYRAQ-ASQATPVNLTNHSYFNLAGQASPNINDH 192
Query: 594 KIQLLAKKITPVDEELIPTGEITSIEGTPYDFLEPREIGGRIHELP-GGYDINYVIEGKA 770
++ + A PVDE LIPTGE+ ++GT +D +P E+G + + G+D N+ ++G
Sbjct: 193 EVTIEADTYLPVDETLIPTGEVAPVQGTAFDLRKPVELGKHLQDFHLNGFDHNFCLKGSK 252
Query: 771 GKHLRKTAVVSEGVSGRKMELWSNQPGVQFYTSNLLKSVV-GKGNTVYKKYAGLCLETQG 947
KH A V SGR +E+++ QPGVQFYT N L + GK VY K++G CLETQ
Sbjct: 253 EKHF--CARVHHAASGRVLEVYTTQPGVQFYTGNFLDGTLKGKNGAVYPKHSGFCLETQN 310
Query: 948 FPDSVNHKNFPSQIVNPGESYLHVMLFRFA 1037
+PD+VN FP ++ PGE Y H F+F+
Sbjct: 311 WPDAVNQPRFPPVLLRPGEEYDHTTWFKFS 340
Score = 69 bits (167), Expect = 5e-011
Identities = 33/87 (37%), Positives = 52/87 (59%)
Frame = +1
Query: 154 IKTYKLTRGKLSVTFTNYGAVMTSLLLPDRHGKQGDVVLGFDTVDAYKNDTTYFGAIVGR 333
++ ++L L V ++G +T+L + DR G+ DVVLGF ++ Y YFGA++GR
Sbjct: 19 VEKFQLQSDLLRVDIISWGCTITALEVKDRQGRASDVVLGFAELEGYLQKQPYFGAVIGR 78
Query: 334 VANRIGGAKFKLNGQLYKTDANEGHNT 414
VANRI FK++G+ Y N+ N+
Sbjct: 79 VANRIAKGTFKVDGKEYHLAINKEPNS 105
>sp|Q8K157|GALM_MOUSE Aldose 1-epimerase OS=Mus musculus GN=Galm PE=2 SV=1
Length = 342
Score = 174 bits (440), Expect = 1e-042
Identities = 93/210 (44%), Positives = 127/210 (60%), Gaps = 6/210 (2%)
Frame = +3
Query: 414 DGEEGFPGNVTVMVTYMLIGENELALKMEAKPLDKPTPINLALHTYWNLHGHNSGDILSH 593
DGEEG+PG + V VTY L G EL + A+ + TP+NL H+Y+NL G S +I H
Sbjct: 135 DGEEGYPGELKVWVTYTLDG-GELVINYRAQ-ASQTTPVNLTNHSYFNLAGQGSPNIYDH 192
Query: 594 KIQLLAKKITPVDEELIPTGEITSIEGTPYDFLEPREIGGRIHELP-GGYDINYVIEGKA 770
++ + A PVDE LIPTG I +EGT +D +P E+G + + G+D N+ + K
Sbjct: 193 EVTIAADAYLPVDETLIPTGVIAPVEGTAFDLRKPVELGTHLQDYHIHGFDHNFCL--KE 250
Query: 771 GKHLRKTAVVSEGVSGRKMELWSNQPGVQFYTSNLLKSVV-GKGNTVYKKYAGLCLETQG 947
K + A V SGR +E+++ QPGVQFYT N L + GK VY K++GLCLETQ
Sbjct: 251 SKEKKFCARVRHAASGRILEVYTTQPGVQFYTGNFLDGTLKGKNGAVYPKHSGLCLETQN 310
Query: 948 FPDSVNHKNFPSQIVNPGESYLHVMLFRFA 1037
+PDSVN FP ++ PGE Y H F+F+
Sbjct: 311 WPDSVNQPQFPPALLRPGEEYNHTTWFKFS 340
Score = 73 bits (178), Expect = 3e-012
Identities = 35/87 (40%), Positives = 52/87 (59%)
Frame = +1
Query: 154 IKTYKLTRGKLSVTFTNYGAVMTSLLLPDRHGKQGDVVLGFDTVDAYKNDTTYFGAIVGR 333
++ ++L +LSV ++G +T+L + DR GK DVVLGF ++ Y YFGA+VGR
Sbjct: 19 VEKFQLRSDQLSVDIISWGCTITALQVKDRQGKASDVVLGFAELEGYLQKQPYFGAVVGR 78
Query: 334 VANRIGGAKFKLNGQLYKTDANEGHNT 414
VANRI +F + G+ Y N N+
Sbjct: 79 VANRIAKGRFTIGGKEYHLPVNREPNS 105
>sp|Q5R8U1|GALM_PONAB Aldose 1-epimerase OS=Pongo abelii GN=GALM PE=2 SV=1
Length = 342
Score = 174 bits (440), Expect = 1e-042
Identities = 90/210 (42%), Positives = 127/210 (60%), Gaps = 6/210 (2%)
Frame = +3
Query: 414 DGEEGFPGNVTVMVTYMLIGENELALKMEAKPLDKPTPINLALHTYWNLHGHNSGDILSH 593
DGEEG+PG + V VTY L G EL + A+ + TP+NL H+Y+NL G S +I H
Sbjct: 135 DGEEGYPGELKVWVTYTLDG-GELVVNYRAQ-ASQATPVNLTNHSYFNLAGQGSPNIYDH 192
Query: 594 KIQLLAKKITPVDEELIPTGEITSIEGTPYDFLEPREIGGRIHELP-GGYDINYVIEGKA 770
++ + A PVDE LIPTGE+ ++GT +D +P E+G + + G+D N+ ++G
Sbjct: 193 EVTIEADTYLPVDETLIPTGEVAPVQGTAFDLRKPVELGKHLQDFHLNGFDHNFCLKGSK 252
Query: 771 GKHLRKTAVVSEGVSGRKMELWSNQPGVQFYTSNLLKSVV-GKGNTVYKKYAGLCLETQG 947
KH A V SGR +E+++ QPGVQFY N L + GK VY K++G CLETQ
Sbjct: 253 EKHF--CARVHHAASGRVLEVYTTQPGVQFYMGNFLDGTLKGKNGAVYPKHSGFCLETQN 310
Query: 948 FPDSVNHKNFPSQIVNPGESYLHVMLFRFA 1037
+PD+VN FP ++ PGE Y H F+F+
Sbjct: 311 WPDAVNQPRFPPVLLRPGEEYDHTTWFKFS 340
Score = 69 bits (168), Expect = 4e-011
Identities = 33/87 (37%), Positives = 52/87 (59%)
Frame = +1
Query: 154 IKTYKLTRGKLSVTFTNYGAVMTSLLLPDRHGKQGDVVLGFDTVDAYKNDTTYFGAIVGR 333
++ ++L L V ++G +T+L + DR G+ DVVLGF ++ Y YFGA++GR
Sbjct: 19 VEKFQLQSDLLRVDIISWGCTITALEVKDRQGRSSDVVLGFAELEGYLQKQPYFGAVIGR 78
Query: 334 VANRIGGAKFKLNGQLYKTDANEGHNT 414
VANRI FK++G+ Y N+ N+
Sbjct: 79 VANRIAKGTFKVDGKEYHLAINKEPNS 105
>sp|Q5EA79|GALM_BOVIN Aldose 1-epimerase OS=Bos taurus GN=GALM PE=2 SV=1
Length = 342
Score = 172 bits (435), Expect = 5e-042
Identities = 92/210 (43%), Positives = 128/210 (60%), Gaps = 6/210 (2%)
Frame = +3
Query: 414 DGEEGFPGNVTVMVTYMLIGENELALKMEAKPLDKPTPINLALHTYWNLHGHNSGDILSH 593
DGEEG+PG + V V Y L G EL + A+ + TP+NL H+Y+NL G S +I H
Sbjct: 135 DGEEGYPGELKVWVMYTLDG-GELVVNYRAQ-ASQTTPVNLTNHSYFNLAGQGSPNIYDH 192
Query: 594 KIQLLAKKITPVDEELIPTGEITSIEGTPYDFLEPREIGGRIHEL-PGGYDINYVIEGKA 770
++ + A PVDE LIPTGEI S++GT +D +P E+G + E G+D N+ ++G
Sbjct: 193 EVTIEADAFLPVDEVLIPTGEIASVQGTAFDLRKPVELGKHLQEFHVNGFDHNFCLKG-- 250
Query: 771 GKHLRKTAVVSEGVSGRKMELWSNQPGVQFYTSNLLKSVV-GKGNTVYKKYAGLCLETQG 947
K R A V SGR +E+++ QPGVQFYT N L + GK Y K++G CLETQ
Sbjct: 251 SKEKRFCARVHHAGSGRVLEVYTTQPGVQFYTGNFLDGTLKGKSGAGYPKHSGFCLETQS 310
Query: 948 FPDSVNHKNFPSQIVNPGESYLHVMLFRFA 1037
+PD+VN +FP ++ PGE Y H F+F+
Sbjct: 311 WPDAVNQPHFPPVLLKPGEEYDHTTWFKFS 340
Score = 77 bits (189), Expect = 2e-013
Identities = 37/87 (42%), Positives = 54/87 (62%)
Frame = +1
Query: 154 IKTYKLTRGKLSVTFTNYGAVMTSLLLPDRHGKQGDVVLGFDTVDAYKNDTTYFGAIVGR 333
++ ++L +L V ++G +T+L + DR G+ DVVLGFD ++ Y YFGA+VGR
Sbjct: 19 VEKFQLQSDQLRVDIISWGCTITALEVKDRQGRASDVVLGFDELEGYLQKQPYFGAVVGR 78
Query: 334 VANRIGGAKFKLNGQLYKTDANEGHNT 414
VANRI F L+G+ YK N G N+
Sbjct: 79 VANRIAKGTFTLDGKEYKLAINNGPNS 105
>sp|Q66HG4|GALM_RAT Aldose 1-epimerase OS=Rattus norvegicus GN=Galm PE=1 SV=1
Length = 342
Score = 171 bits (432), Expect = 1e-041
Identities = 92/210 (43%), Positives = 125/210 (59%), Gaps = 6/210 (2%)
Frame = +3
Query: 414 DGEEGFPGNVTVMVTYMLIGENELALKMEAKPLDKPTPINLALHTYWNLHGHNSGDILSH 593
DGEEG+PG + V VTY L G EL + A+ + TP+NL H+Y+NL G S DI H
Sbjct: 135 DGEEGYPGELKVWVTYTLDG-GELVVNYRAQ-ASQTTPVNLTNHSYFNLAGQGSPDIYDH 192
Query: 594 KIQLLAKKITPVDEELIPTGEITSIEGTPYDFLEPREIGGRIHELP-GGYDINYVIEGKA 770
++ + A PVDE LIPTG I +EGT +D +P E+G + G+D N+ + K
Sbjct: 193 EVTIAADAYLPVDETLIPTGVIAPVEGTAFDLRKPVELGKHLQSYHIHGFDHNFCL--KE 250
Query: 771 GKHLRKTAVVSEGVSGRKMELWSNQPGVQFYTSNLLKSVV-GKGNTVYKKYAGLCLETQG 947
K + A V SGR +E+++ QPGVQFYT N L + GK VY K++G CLETQ
Sbjct: 251 SKEKKFCARVHHAASGRILEVYTTQPGVQFYTGNFLDGTLKGKSGEVYPKHSGFCLETQN 310
Query: 948 FPDSVNHKNFPSQIVNPGESYLHVMLFRFA 1037
+PD+VN FP ++ PGE Y H F+F+
Sbjct: 311 WPDAVNQPQFPPILLRPGEEYNHTTWFKFS 340
Score = 72 bits (174), Expect = 8e-012
Identities = 34/87 (39%), Positives = 53/87 (60%)
Frame = +1
Query: 154 IKTYKLTRGKLSVTFTNYGAVMTSLLLPDRHGKQGDVVLGFDTVDAYKNDTTYFGAIVGR 333
++ ++L +L+V ++G +T+L + DR GK DVVLGF ++ Y YFGA+VGR
Sbjct: 19 VEKFQLRSDQLNVDIISWGCTITALQVKDRQGKASDVVLGFAELEGYLQKQPYFGAVVGR 78
Query: 334 VANRIGGAKFKLNGQLYKTDANEGHNT 414
VANRI +F ++G+ Y N N+
Sbjct: 79 VANRIAKGRFTVDGKEYHLPINREPNS 105
>sp|Q9GKX6|GALM_PIG Aldose 1-epimerase OS=Sus scrofa GN=GALM PE=2 SV=1
Length = 342
Score = 168 bits (425), Expect = 7e-041
Identities = 90/210 (42%), Positives = 127/210 (60%), Gaps = 6/210 (2%)
Frame = +3
Query: 414 DGEEGFPGNVTVMVTYMLIGENELALKMEAKPLDKPTPINLALHTYWNLHGHNSGDILSH 593
DGEEG+PG + V VTY L G EL + A+ + TP+NL H+Y+NL G S +I H
Sbjct: 135 DGEEGYPGELKVWVTYTLDG-GELVVNYRAQ-ASQTTPVNLTNHSYFNLAGQGSPNIYDH 192
Query: 594 KIQLLAKKITPVDEELIPTGEITSIEGTPYDFLEPREIGGRIHELP-GGYDINYVIEGKA 770
++ + A PVDE LIPTGEI ++GT +D +P E+G + E G+D N+ + K
Sbjct: 193 EVTIEADAFLPVDETLIPTGEIAPVQGTAFDLRKPVELGKHLQEFHINGFDHNFCL--KR 250
Query: 771 GKHLRKTAVVSEGVSGRKMELWSNQPGVQFYTSNLLKSVV-GKGNTVYKKYAGLCLETQG 947
K + A V SGR +E+++ QPG+QFYT N L + GK VY K++G CLETQ
Sbjct: 251 SKEKQFCARVHHAGSGRVLEVYTTQPGIQFYTGNFLDGTLKGKTGAVYPKHSGFCLETQN 310
Query: 948 FPDSVNHKNFPSQIVNPGESYLHVMLFRFA 1037
+P++VN +FP ++ PGE Y H F F+
Sbjct: 311 WPNAVNQPHFPPVLLKPGEEYNHTTWFVFS 340
Score = 72 bits (176), Expect = 5e-012
Identities = 36/87 (41%), Positives = 52/87 (59%)
Frame = +1
Query: 154 IKTYKLTRGKLSVTFTNYGAVMTSLLLPDRHGKQGDVVLGFDTVDAYKNDTTYFGAIVGR 333
++ ++L +L V ++G +T+L + DR G+ DVVLGF + Y YFGA+VGR
Sbjct: 19 VEKFQLQSDQLRVDIISWGCTITALEVKDRQGRASDVVLGFAELKEYLQKHPYFGAVVGR 78
Query: 334 VANRIGGAKFKLNGQLYKTDANEGHNT 414
VANRI F L+G+ YK N G N+
Sbjct: 79 VANRIAKGTFTLDGKEYKLAINNGPNS 105
>sp|P05149|GALM_ACICA Aldose 1-epimerase OS=Acinetobacter calcoaceticus GN=mro
PE=1 SV=1
Length = 381
Score = 151 bits (380), Expect = 1e-035
Identities = 86/216 (39%), Positives = 127/216 (58%), Gaps = 10/216 (4%)
Frame = +3
Query: 414 DGEEGFPGNVTVMVTYMLIGENELALKMEAKPLDKPTPINLALHTYWNLH--GHNSGDIL 587
+G++GFPG + V V Y L +NE ++ +AK D+PT +NL H+Y+NL G+N +L
Sbjct: 163 NGDQGFPGKLDVEVIYSLSDQNEFKIEYKAK-TDQPTVVNLTNHSYFNLSGAGNNPYGVL 221
Query: 588 SHKIQLLAKKITPVDEELIPTGEITSIEGTPYDFLEPREIGGRIH------ELPGGYDIN 749
H +QL A +I D+ +PTGEI S+ GTP+DF P+ I I GYD
Sbjct: 222 DHVVQLNAGRILVTDQNSLPTGEIASVAGTPFDFRMPKAIVKDIRANNQQLAYGYGYDQT 281
Query: 750 YVIEGKAGKHLRKTAVVSEGVSGRKMELWSNQPGVQFYTS-NLLKSVVGKGNTVYKKYAG 926
+VI K+ L A+V + S R M++ + +P VQ YT+ +LL ++VG +Y++
Sbjct: 282 WVINQKSQGKLNLAAIVVDPKSKRTMQVLTTEPSVQMYTADHLLGNIVGANGVLYRQADA 341
Query: 927 LCLETQGFPDSVNHKNFPSQIVNPGESYLHVMLFRF 1034
L LETQ FPDS N FPS +NP ++Y V +F+F
Sbjct: 342 LALETQHFPDSPNQPTFPSTRLNPNQTYNSVTVFKF 377
Score = 80 bits (195), Expect = 3e-014
Identities = 39/89 (43%), Positives = 58/89 (65%), Gaps = 5/89 (5%)
Frame = +1
Query: 184 LSVTFTNYGAVMTSLLLPDRHGKQGDVVLGFDTVDAYKNDTT----YFGAIVGRVANRIG 351
+SV+F ++G V+T +L PD GKQ ++VLGFD + Y+ T +FG ++GR ANRIG
Sbjct: 48 VSVSFISFGGVITQILTPDAQGKQNNIVLGFDDLKGYEVTDTKEGIHFGGLIGRYANRIG 107
Query: 352 GAKFKLNGQLYKTDANEGHNTTVKKDSPG 438
AKF L+G+ Y + N G N ++ +PG
Sbjct: 108 NAKFSLDGKTYNLEKNNGPN-SLHSGNPG 135
>sp|P04397|GAL10_YEAST Bifunctional protein GAL10 OS=Saccharomyces cerevisiae
GN=GAL10 PE=1 SV=2
Length = 699
Score = 67 bits (163), Expect = 2e-010
Identities = 53/212 (25%), Positives = 98/212 (46%), Gaps = 22/212 (10%)
Frame = +3
Query: 429 FPGNVTVMVTYML-IGENELALKMEAK-PLDKPTPINLALHTYWNLHGHNSGDILSHKIQ 602
FPG++ V + Y + + + L + + K + TPINL H+Y+NL+ I +I
Sbjct: 497 FPGDLLVTIQYTVNVAQKSLEMVYKGKLTAGEATPINLTNHSYFNLNKPYGDTIEGTEIM 556
Query: 603 LLAKKITPVDEELIPTGEITSIEGTPYDFLEPREIGGRIHELPGGYDINYVIEGKA---- 770
+ +KK VD+ +IPTG I E ++ +P +G + + +D +V++ A
Sbjct: 557 VRSKKSVDVDKNMIPTGNIVDREIATFNSTKPTVLGPKNPQ----FDCCFVVDENAKPSQ 612
Query: 771 ----GKHLRKTAVVSEGVSGRKMELWSNQPGVQFYTSNLLKSVVGKGNTVYKKYAGLCLE 938
L S +E+ S +P QFYT + L + Y+ G +E
Sbjct: 613 INTLNNELTLIVKAFHPDSNITLEVLSTEPTYQFYTGDFL-------SAGYEARQGFAIE 665
Query: 939 TQGFPDSVNHKNFPSQI-VNPGESYLHVMLFR 1031
+ D++N +N+ + + GE+Y +++R
Sbjct: 666 PGRYIDAINQENWKDCVTLKNGETYGSKIVYR 697
>sp|P31765|GALM_HAEIN Aldose 1-epimerase OS=Haemophilus influenzae GN=galM PE=3
SV=2
Length = 340
Score = 53 bits (125), Expect = 4e-006
Identities = 31/74 (41%), Positives = 44/74 (59%), Gaps = 2/74 (2%)
Frame = +1
Query: 184 LSVTFTNYGAVMTSLLLPDRHGKQGDVVLGFDTVDAYKNDTTYFGAIVGRVANRIGGAKF 363
+ V F ++GA S +P + +V+LG VD Y +Y GA VGR ANRI A+F
Sbjct: 26 MRVQFMDWGATWLSCKVPVNDTLR-EVLLGC-KVDNYPTHQSYLGASVGRYANRIANAQF 83
Query: 364 KLNGQLYKTDANEG 405
+LNG+L K +N+G
Sbjct: 84 ELNGELIKLSSNQG 97
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,894,514,945
Number of Sequences: 518415
Number of Extensions: 45894514945
Number of Successful Extensions: 338263929
Number of sequences better than 0.0: 0
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