BLASTX 7.6.2
Query= UN11531 /QuerySize=764
(763 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P42785|PCP_HUMAN Lysosomal Pro-X carboxypeptidase OS=Homo sap... 179 2e-044
sp|Q7TMR0|PCP_MOUSE Lysosomal Pro-X carboxypeptidase OS=Mus musc... 178 4e-044
sp|Q5RBU7|PCP_PONAB Lysosomal Pro-X carboxypeptidase OS=Pongo ab... 177 1e-043
sp|Q2TA14|PCP_BOVIN Lysosomal Pro-X carboxypeptidase OS=Bos taur... 168 5e-041
sp|Q9ET22|DPP2_MOUSE Dipeptidyl peptidase 2 OS=Mus musculus GN=D... 160 1e-038
sp|Q9EPB1|DPP2_RAT Dipeptidyl peptidase 2 OS=Rattus norvegicus G... 160 1e-038
sp|Q9UHL4|DPP2_HUMAN Dipeptidyl peptidase 2 OS=Homo sapiens GN=D... 159 2e-038
sp|P34676|PCP5_CAEEL Prolyl carboxy peptidase like protein 5 OS=... 157 9e-038
sp|P34610|PCP1_CAEEL Putative serine protease pcp-1 OS=Caenorhab... 150 1e-035
sp|P90893|YM9I_CAEEL Putative serine protease F56F10.1 OS=Caenor... 99 4e-020
sp|Q9NQE7|TSSP_HUMAN Thymus-specific serine protease OS=Homo sap... 89 2e-017
sp|P34528|YM67_CAEEL Putative serine protease K12H4.7 OS=Caenorh... 89 2e-017
sp|Q9QXE5|TSSP_MOUSE Thymus-specific serine protease OS=Mus musc... 86 2e-016
>sp|P42785|PCP_HUMAN Lysosomal Pro-X carboxypeptidase OS=Homo sapiens GN=PRCP
PE=1 SV=1
Length = 496
Score = 179 bits (454), Expect = 2e-044
Identities = 99/208 (47%), Positives = 127/208 (61%), Gaps = 9/208 (4%)
Frame = +3
Query: 60 ACLCLLFLFFTVFAEATYPPGGFHHLSSLR-QNKKTSKSKSELPFETRYFPQNLDHFSFR 236
A L LL F +A P L SL TS + YF Q +DHF F
Sbjct: 5 ALLLLLLSFLAPWATIALRP-ALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHFGF- 62
Query: 237 PESYKVFHHKYLINRRFWRK-GGPIFVYTGNEGDIDWFASNTGFMSDIAPKFKALLVFIE 413
+ K F+ +YL+ ++W+K GG I YTGNEGDI WF +NTGFM D+A + KA+LVF E
Sbjct: 63 -NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAE 121
Query: 414 HRFYGESTPFGKKSHKTAETLGYLNSQQALADYAILIRSLKQNL-SSEASPVVVFGGSYG 590
HR+YGES PFG S K + L +L S+QALAD+A LI+ LK+ + +E PV+ GGSYG
Sbjct: 122 HRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYG 181
Query: 591 GMLAAWFRLKYPHIAIEHL---HPLLQF 665
GMLAAWFR+KYPH+ + L P+ QF
Sbjct: 182 GMLAAWFRMKYPHMVVGALAASAPIWQF 209
>sp|Q7TMR0|PCP_MOUSE Lysosomal Pro-X carboxypeptidase OS=Mus musculus GN=Prcp
PE=2 SV=2
Length = 491
Score = 178 bits (451), Expect = 4e-044
Identities = 95/199 (47%), Positives = 122/199 (61%), Gaps = 13/199 (6%)
Frame = +3
Query: 63 CLCLLFLFFTVFAEATYPPG-----GFHHLSSLRQNKKTSKSKSELPFETRYFPQNLDHF 227
C LL L F + AT P G HLS+ T + YF Q +DHF
Sbjct: 3 CRALLLLSFLLLGAATTIPPRLKTLGSPHLSA----SPTPDPAVARKYSVLYFEQKVDHF 58
Query: 228 SFRPESYKVFHHKYLINRRFW-RKGGPIFVYTGNEGDIDWFASNTGFMSDIAPKFKALLV 404
F + F +YL+ + W R GG I YTGNEGDI WF +NTGFM D+A + KA+LV
Sbjct: 59 GF--ADMRTFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLV 116
Query: 405 FIEHRFYGESTPFGKKSHKTAETLGYLNSQQALADYAILIRSLKQNL-SSEASPVVVFGG 581
F EHR+YGES PFG+ S K ++ L +L S+QALAD+A LIR L++ + ++ PV+ GG
Sbjct: 117 FAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGG 176
Query: 582 SYGGMLAAWFRLKYPHIAI 638
SYGGMLAAWFR+KYPHI +
Sbjct: 177 SYGGMLAAWFRMKYPHIVV 195
>sp|Q5RBU7|PCP_PONAB Lysosomal Pro-X carboxypeptidase OS=Pongo abelii GN=PRCP
PE=2 SV=1
Length = 496
Score = 177 bits (447), Expect = 1e-043
Identities = 97/208 (46%), Positives = 126/208 (60%), Gaps = 9/208 (4%)
Frame = +3
Query: 60 ACLCLLFLFFTVFAEATYPPGGFHHLSSLR-QNKKTSKSKSELPFETRYFPQNLDHFSFR 236
A L LL F + P L SL TS + YF Q +DHF F
Sbjct: 5 ALLLLLLSFLAPWTTIALRP-ALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHFGF- 62
Query: 237 PESYKVFHHKYLINRRFWRK-GGPIFVYTGNEGDIDWFASNTGFMSDIAPKFKALLVFIE 413
+ K F+ +YL+ ++W+K GG I YTGNEGDI WF +NTGFM D+A + KA+LVF E
Sbjct: 63 -NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAE 121
Query: 414 HRFYGESTPFGKKSHKTAETLGYLNSQQALADYAILIRSLKQNL-SSEASPVVVFGGSYG 590
HR+YGES PFG + K + L +L S+QALAD+A LI+ LK+ + +E PV+ GGSYG
Sbjct: 122 HRYYGESLPFGDNTFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYG 181
Query: 591 GMLAAWFRLKYPHIAIEHL---HPLLQF 665
GMLAAWFR+KYPH+ + L P+ QF
Sbjct: 182 GMLAAWFRMKYPHMVVGALAASAPIWQF 209
>sp|Q2TA14|PCP_BOVIN Lysosomal Pro-X carboxypeptidase OS=Bos taurus GN=PRCP PE=2
SV=1
Length = 499
Score = 168 bits (424), Expect = 5e-041
Identities = 86/173 (49%), Positives = 113/173 (65%), Gaps = 7/173 (4%)
Frame = +3
Query: 165 SKSKSELPFETRYFPQNLDHFSFRPESYKVFHHKYLINRRFWRK-GGPIFVYTGNEGDID 341
S+ L + RY Q +DHF F + + F +YLI +W++ GG I YTGNEGDI
Sbjct: 42 SRPTITLKYSIRYIQQKVDHFGFNID--RTFKQRYLIADNYWKEDGGSILFYTGNEGDII 99
Query: 342 WFASNTGFMSDIAPKFKALLVFIEHRFYGESTPFGKKSHKTAETLGYLNSQQALADYAIL 521
WF +NTGFM DIA + KA+LVF EHR+YGES PFG S + L +L ++QALAD+A L
Sbjct: 100 WFCNNTGFMWDIAEEMKAMLVFAEHRYYGESLPFGADSFSDSRHLNFLTTEQALADFAKL 159
Query: 522 IRSLKQNL-SSEASPVVVFGGSYGGMLAAWFRLKYPHIAIEHL---HPLLQFS 668
IR LK+ + + V+ GGSYGGMLAAWFR+KYPH+ + L P+ QF+
Sbjct: 160 IRYLKRTIPGARNQHVIALGGSYGGMLAAWFRMKYPHLVVGALASSAPIWQFN 212
>sp|Q9ET22|DPP2_MOUSE Dipeptidyl peptidase 2 OS=Mus musculus GN=Dpp7 PE=2 SV=1
Length = 506
Score = 160 bits (404), Expect = 1e-038
Identities = 76/149 (51%), Positives = 108/149 (72%), Gaps = 2/149 (1%)
Frame = +3
Query: 189 FETRYFPQNLDHFSFRPESYKVFHHKYLINRRFWRKG-GPIFVYTGNEGDIDWFASNTGF 365
F YF Q +DHF+F K F ++L++ +FW+ G GPIF YTGNEGDI FA+N+GF
Sbjct: 41 FHENYFEQYMDHFNFESFGNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDIWSFANNSGF 100
Query: 366 MSDIAPKFKALLVFIEHRFYGESTPFGKKSHKTAETLGYLNSQQALADYAILIRSLKQNL 545
M ++A + +ALLVF EHR+YG+S PFG +S + T L +QALAD+A+L+++L+Q+L
Sbjct: 101 MVELAAQQEALLVFAEHRYYGKSLPFGVQSTQRGYT-QLLTVEQALADFAVLLQALRQDL 159
Query: 546 SSEASPVVVFGGSYGGMLAAWFRLKYPHI 632
+P + FGGSYGGML+A+ R+KYPH+
Sbjct: 160 GVHDAPTIAFGGSYGGMLSAYMRMKYPHL 188
>sp|Q9EPB1|DPP2_RAT Dipeptidyl peptidase 2 OS=Rattus norvegicus GN=Dpp7 PE=1
SV=1
Length = 500
Score = 160 bits (403), Expect = 1e-038
Identities = 77/158 (48%), Positives = 112/158 (70%), Gaps = 2/158 (1%)
Frame = +3
Query: 162 TSKSKSELPFETRYFPQNLDHFSFRPESYKVFHHKYLINRRFWRKG-GPIFVYTGNEGDI 338
T+ S + F YF Q +DHF+F S K F ++L++ +FW+ G GPIF YTGNEGDI
Sbjct: 32 TADSVLDPDFRENYFEQYMDHFNFESFSNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDI 91
Query: 339 DWFASNTGFMSDIAPKFKALLVFIEHRFYGESTPFGKKSHKTAETLGYLNSQQALADYAI 518
A+N+GF+ ++A + +ALLVF EHR+YG+S PFG +S + T L +QALAD+A+
Sbjct: 92 WSLANNSGFIVELAAQQEALLVFAEHRYYGKSLPFGVQSTQRGYT-QLLTVEQALADFAV 150
Query: 519 LIRSLKQNLSSEASPVVVFGGSYGGMLAAWFRLKYPHI 632
L+++L+ NL + +P + FGGSYGGML+A+ R+KYPH+
Sbjct: 151 LLQALRHNLGVQDAPTIAFGGSYGGMLSAYMRMKYPHL 188
>sp|Q9UHL4|DPP2_HUMAN Dipeptidyl peptidase 2 OS=Homo sapiens GN=DPP7 PE=1 SV=3
Length = 492
Score = 159 bits (402), Expect = 2e-038
Identities = 75/149 (50%), Positives = 110/149 (73%), Gaps = 2/149 (1%)
Frame = +3
Query: 189 FETRYFPQNLDHFSFRPESYKVFHHKYLINRRFWRKG-GPIFVYTGNEGDIDWFASNTGF 365
F+ R+F Q LDHF+F K F ++L++ RFW +G GPIF YTGNEGD+ FA+N+ F
Sbjct: 31 FQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAF 90
Query: 366 MSDIAPKFKALLVFIEHRFYGESTPFGKKSHKTAETLGYLNSQQALADYAILIRSLKQNL 545
++++A + ALLVF EHR+YG+S PFG +S + T L +QALAD+A L+R+L+++L
Sbjct: 91 VAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHT-ELLTVEQALADFAELLRALRRDL 149
Query: 546 SSEASPVVVFGGSYGGMLAAWFRLKYPHI 632
++ +P + FGGSYGGML+A+ R+KYPH+
Sbjct: 150 GAQDAPAIAFGGSYGGMLSAYLRMKYPHL 178
>sp|P34676|PCP5_CAEEL Prolyl carboxy peptidase like protein 5 OS=Caenorhabditis
elegans GN=pcp-5 PE=1 SV=1
Length = 507
Score = 157 bits (396), Expect = 9e-038
Identities = 83/177 (46%), Positives = 112/177 (63%), Gaps = 7/177 (3%)
Frame = +3
Query: 159 KTSKSKSELPFETRYFPQNLDHFSFRPESYKVFHHKYLINRRFWRKGGPIFVYTGNEGDI 338
K KS + +E Y +D F+F + F +Y +N + GGPI YTGNEG +
Sbjct: 31 KFEKSIGKYKYEEGYLKAPIDPFAFTND--LEFDLRYFLNIDHYETGGPILFYTGNEGSL 88
Query: 339 DWFASNTGFMSDIAPKFKALLVFIEHRFYGESTPFGKKSHKTAETLGYLNSQQALADYAI 518
+ FA NTGFM D+AP+ KA +VF+EHRFYG+S PF +S+ LGYL+SQQALAD+A+
Sbjct: 89 EAFAENTGFMWDLAPELKAAVVFVEHRFYGKSQPFKNESYTDIRHLGYLSSQQALADFAL 148
Query: 519 LIRSLKQN--LSSEASPVVVFGGSYGGMLAAWFRLKYPHI---AIEHLHPLLQFSIS 674
++ K ++ S V+ FGGSYGGML+AWFR+KYPHI AI P+ F+ S
Sbjct: 149 SVQFFKNEKIKGAQKSAVIAFGGSYGGMLSAWFRIKYPHIVDGAIAASAPVFWFTDS 205
>sp|P34610|PCP1_CAEEL Putative serine protease pcp-1 OS=Caenorhabditis elegans
GN=pcp-1 PE=1 SV=2
Length = 565
Score = 150 bits (377), Expect = 1e-035
Identities = 73/150 (48%), Positives = 100/150 (66%), Gaps = 8/150 (5%)
Frame = +3
Query: 201 YFPQNLDHFSFRPESYKVFHHKYLINRRFWRKGGPIFVYTGNEGDIDWFASNTGFMSDIA 380
Y LDHF++ + F + + N F++ GGPIF YTGNEG ++ F + TG M D+A
Sbjct: 46 YKNMKLDHFTW--GDTRTFDMRVMWNNTFYKPGGPIFFYTGNEGGLESFVTATGMMFDLA 103
Query: 381 PKFKALLVFIEHRFYGESTPFGKKSHKTAETLGYLNSQQALADYAILIRSLKQNLSS--- 551
P F A ++F EHRFYG++ PFG +S+ + +GYL S+QALADYA L+ LK++ +
Sbjct: 104 PMFNASIIFAEHRFYGQTQPFGNQSYASLANVGYLTSEQALADYAELLTELKRDNNQFKM 163
Query: 552 ---EASPVVVFGGSYGGMLAAWFRLKYPHI 632
A+ V+ FGGSYGGML+AWFR KYPHI
Sbjct: 164 TFPAATQVISFGGSYGGMLSAWFRQKYPHI 193
>sp|P90893|YM9I_CAEEL Putative serine protease F56F10.1 OS=Caenorhabditis
elegans GN=F56F10.1 PE=1 SV=2
Length = 540
Score = 99 bits (244), Expect = 4e-020
Identities = 63/172 (36%), Positives = 84/172 (48%), Gaps = 7/172 (4%)
Frame = +3
Query: 129 HHLSSLRQNKKTSKSKSELPFETRYFPQNLDHFSFRPESYKVFHHKYLINRRFWRKGGPI 308
HHL L + S ++ + F Q LDHF P + K ++ KY N F R I
Sbjct: 34 HHLDRLTASDGASIQETYPNLQVHNFTQKLDHFD--PYNTKTWNQKYFYNPVFSRNNSII 91
Query: 309 FVYTGNEGDID--WFASNTGFMSDIAPKFKALLVFIEHRFYGESTPFGKKSHKTAETLGY 482
F+ G EG + W A+ A +F A + +EHRF+G+S P +L Y
Sbjct: 92 FLMIGGEGPENGKWAANPNVQYLQWAKEFGADVFDLEHRFFGDSWPI---PDMQTSSLRY 148
Query: 483 LNSQQALADYAILIRSLKQNLSSEASPVVVFGGSYGGMLAAWFRLKYPHIAI 638
L +QQALAD A I + Q + V FGGSY G LAAWFR KYP + +
Sbjct: 149 LTTQQALADLAFFIEFMNQQYGFKNPRWVTFGGSYPGSLAAWFRQKYPQLTV 200
>sp|Q9NQE7|TSSP_HUMAN Thymus-specific serine protease OS=Homo sapiens GN=PRSS16
PE=2 SV=2
Length = 514
Score = 89 bits (220), Expect = 2e-017
Identities = 56/137 (40%), Positives = 79/137 (57%), Gaps = 7/137 (5%)
Frame = +3
Query: 231 FRPESYKVFHHKYLINRRFW-RKGGPIFVYTGNEGDIDWFASNTGFMSDIAPKFKALLVF 407
F + F +Y +N + W + GPIF++ G EG + + G + +AP + AL++
Sbjct: 69 FNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAPAWGALVIS 128
Query: 408 IEHRFYGESTPFGKKSHKTAETLGYLNSQQALADY--AILIRSLKQNLSSEASPVVVFGG 581
+EHRFYG S P G L +L+S+ ALAD A L S N+SS +SP + FGG
Sbjct: 129 LEHRFYGLSIPAGGLE---MAQLRFLSSRLALADVVSARLALSRLFNISS-SSPWICFGG 184
Query: 582 SYGGMLAAWFRLKYPHI 632
SY G LAAW RLK+PH+
Sbjct: 185 SYAGSLAAWARLKFPHL 201
>sp|P34528|YM67_CAEEL Putative serine protease K12H4.7 OS=Caenorhabditis elegans
GN=K12H4.7 PE=1 SV=2
Length = 510
Score = 89 bits (220), Expect = 2e-017
Identities = 56/146 (38%), Positives = 80/146 (54%), Gaps = 8/146 (5%)
Frame = +3
Query: 204 FPQNLDHFSFRPESYKVFHHKYLINRRFWRKGGPIFVYTGNEG-DIDWFASNTGF-MSDI 377
F Q LDHF K F +Y N ++++ GGP F+ G EG + ++ S G ++++
Sbjct: 63 FTQTLDHFD--SSVGKTFQQRYYHNNQWYKAGGPAFLMLGGEGPESSYWVSYPGLEITNL 120
Query: 378 APKFKALLVFIEHRFYGESTPFGKKSHKTAETLGYLNSQQALADYAILIRSLKQNLSSEA 557
A K A + IEHRFYGE+ P S + L YL+S QA+ D A I+++ A
Sbjct: 121 AAKQGAWVFDIEHRFYGETHP---TSDMSVPNLKYLSSAQAIEDAAAFIKAMTAKFPQLA 177
Query: 558 SPV-VVFGGSYGGMLAAWFRLKYPHI 632
+ V FGGSY G LAAW R K+P +
Sbjct: 178 NAKWVTFGGSYSGALAAWTRAKHPEL 203
>sp|Q9QXE5|TSSP_MOUSE Thymus-specific serine protease OS=Mus musculus GN=Prss16
PE=2 SV=1
Length = 509
Score = 86 bits (211), Expect = 2e-016
Identities = 53/137 (38%), Positives = 77/137 (56%), Gaps = 7/137 (5%)
Frame = +3
Query: 231 FRPESYKVFHHKYLINRRFWRKGG--PIFVYTGNEGDIDWFASNTGFMSDIAPKFKALLV 404
F + F +Y +N + R G P+F++ G EG + + G + +AP + AL++
Sbjct: 68 FNASDRRTFLQRYWVNDQH-RTGQDVPVFLHIGGEGSLGPGSVMAGHPAALAPAWGALVI 126
Query: 405 FIEHRFYGESTPFGKKSHKTAETLGYLNSQQALADYAILIRSLKQNLS-SEASPVVVFGG 581
+EHRFYG S P G L YL+S+ ALAD A ++L L+ S +SP + FGG
Sbjct: 127 SLEHRFYGLSMPAGGLD---LALLRYLSSRHALADVASARQALSGLLNVSSSSPWICFGG 183
Query: 582 SYGGMLAAWFRLKYPHI 632
SY G LA W RLK+PH+
Sbjct: 184 SYAGSLATWARLKFPHL 200
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,851,905,190
Number of Sequences: 518415
Number of Extensions: 48851905190
Number of Successful Extensions: 346316827
Number of sequences better than 0.0: 0
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