BLASTX 7.6.2
Query= UN11589 /QuerySize=954
(953 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9VDL1|U483_DROME UPF0483 protein CG5412 OS=Drosophila melano... 75 8e-013
sp|Q29BR3|U483_DROPS UPF0483 protein GA18864 OS=Drosophila pseud... 69 3e-011
sp|P36591|DYR_SCHPO Dihydrofolate reductase OS=Schizosaccharomyc... 65 8e-010
sp|Q99369|FSH3_YEAST Family of serine hydrolases 3 OS=Saccharomy... 61 1e-008
sp|Q3SZ07|OVCA2_BOVIN Ovarian cancer-associated gene 2 protein h... 57 2e-007
sp|Q05015|FSH2_YEAST Family of serine hydrolases 2 OS=Saccharomy... 57 2e-007
sp|Q9D7E3|OVCA2_MOUSE Ovarian cancer-associated gene 2 protein h... 56 4e-007
sp|A4II73|OVCA2_XENTR Ovarian cancer-associated gene 2 protein h... 55 6e-007
sp|Q8WZ82|OVCA2_HUMAN Ovarian cancer-associated gene 2 protein O... 53 3e-006
>sp|Q9VDL1|U483_DROME UPF0483 protein CG5412 OS=Drosophila melanogaster
GN=CG5412 PE=2 SV=1
Length = 279
Score = 75 bits (182), Expect = 8e-013
Identities = 58/178 (32%), Positives = 86/178 (48%), Gaps = 21/178 (11%)
Frame = +2
Query: 137 IVRKPRFLCLHGFRTSGEIMKIQLHKWPKSVIDRLDLVFLDAPFPCQG-KSDVEGIFDPP 313
I K R LCLHG+R +GE K +L + K + VF+ AP + +S E + P
Sbjct: 27 ITEKVRVLCLHGYRQNGEAFKNKLGSFRKFANKYAEFVFITAPHVAKALESAAEPV--PE 84
Query: 314 YYEWFQFNKEFNEY--TN-------FENCLEYLEDSMIKLGPFDGLIGFSQGAILSGGLP 466
W+ NK+ + TN F+ L +E++ GPF GL+GFSQGA G +
Sbjct: 85 QRSWWA-NKDDGSFKGTNKGGPAFGFQESLRCVEEAWRTQGPFQGLLGFSQGACFVGLIC 143
Query: 467 GLQARGIALQKVPKIK--FIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETDFLKP 634
GL A +K+ I+ F ++ G + V AY + P+LH G+TD + P
Sbjct: 144 GL-----AKKKLTSIRPEFAVLASG-FLSGSLVHMSAYEEAISIPTLHIYGQTDEIIP 195
>sp|Q29BR3|U483_DROPS UPF0483 protein GA18864 OS=Drosophila pseudoobscura
pseudoobscura GN=GA18864 PE=3 SV=1
Length = 289
Score = 69 bits (168), Expect = 3e-011
Identities = 53/177 (29%), Positives = 82/177 (46%), Gaps = 19/177 (10%)
Frame = +2
Query: 137 IVRKPRFLCLHGFRTSGEIMKIQLHKWPKSVIDRLDLVFLDAPFPCQGKSDVEGIFDP-P 313
I K R LCLHG+R G+ K +L + K + VF+ AP + +E +P P
Sbjct: 27 ITEKVRVLCLHGYRQDGDAFKNKLGSFRKFTSKYAEFVFISAPHIA---APLESAAEPVP 83
Query: 314 YYEWFQFNKEFNEY--TN-------FENCLEYLEDSMIKLGPFDGLIGFSQGAILSGGLP 466
+ NK+ + TN F++ L +E++ GPF GL+GFSQGA G +
Sbjct: 84 EQRSWWANKDDGTFKGTNKGGPAFGFQDSLRLVEEAWKTQGPFQGLLGFSQGACFVGLIC 143
Query: 467 GLQARGIALQKVPKIK-FIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETDFLKP 634
GL A +K+ I+ ++ + V AY + P+LH G +D + P
Sbjct: 144 GL-----AKKKLTSIRPEFAVLSSGFVSGSLVHMSAYEEPVSIPTLHIYGSSDEIIP 195
>sp|P36591|DYR_SCHPO Dihydrofolate reductase OS=Schizosaccharomyces pombe
GN=dfr1 PE=2 SV=2
Length = 461
Score = 65 bits (156), Expect = 8e-010
Identities = 40/110 (36%), Positives = 58/110 (52%), Gaps = 6/110 (5%)
Frame = +2
Query: 317 YEWFQFNKEFNEYTNFENCLEYLEDSMIKLGPFDGLIGFSQGAILSGGLPGLQARG---I 487
+ WF+ N Y +++ LE + M + GPFDGLIGFSQGA + L + G
Sbjct: 73 FGWFEVEDFKNTYGSWDESLECINQYMQEKGPFDGLIGFSQGAGIGAMLAQMLQPGQPPN 132
Query: 488 ALQKVPKIKFIIIIGGAMFKSTKVAKD-AYSSTMDTPSLHFLGETDFLKP 634
+ P KF++ +GG F++ K D Y+ + TPSLH G +D L P
Sbjct: 133 PYVQHPPFKFVVFVGG--FRAEKPEFDHFYNPKLTTPSLHIAGTSDTLVP 180
>sp|Q99369|FSH3_YEAST Family of serine hydrolases 3 OS=Saccharomyces cerevisiae
GN=FSH3 PE=1 SV=1
Length = 266
Score = 61 bits (146), Expect = 1e-008
Identities = 40/105 (38%), Positives = 54/105 (51%), Gaps = 4/105 (3%)
Frame = +2
Query: 317 YEWFQFNKE-FNEYTNFENCLEYLEDSMIKLGPFDGLIGFSQGAILSGGLPGLQARGIAL 493
Y WF N E FN + + YL + +++ GPFDG+IGFSQGA L G L R + L
Sbjct: 77 YGWFFRNPESFNSFQIDQKVFNYLRNYVLENGPFDGVIGFSQGAGLGGYLVTDFNRILNL 136
Query: 494 --QKVPKIKFIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETD 622
++ P +KF I G + K+ Y + PSLH GE D
Sbjct: 137 TDEQQPALKFFISFSGFKLEDQSYQKE-YHRIIQVPSLHVRGELD 180
>sp|Q3SZ07|OVCA2_BOVIN Ovarian cancer-associated gene 2 protein homolog OS=Bos
taurus GN=OVCA2 PE=2 SV=1
Length = 227
Score = 57 bits (136), Expect = 2e-007
Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 269 PCQGKSDVEG-IFDPPYYEWFQFNKEFNEYTNFENCLEYLEDSMIKLGPFDGLIGFSQGA 445
PC + +G F + F +E E LE + ++ KLGPFDG++GFSQGA
Sbjct: 63 PCPPEEQPQGWWFSEQEADVFLALEEPTACRGLEEALETVAQALNKLGPFDGILGFSQGA 122
Query: 446 ILSGGLPGLQARGIALQKVPKIKFIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETDF 625
L+ + L G + P +F+I++ G + + + + PSLH G+TD
Sbjct: 123 ALAALVCALGQGGD--PRFPLPRFVILVSGFCPRGLGLMEPIMQGPLSLPSLHVFGDTDG 180
Query: 626 LKP 634
+ P
Sbjct: 181 VIP 183
>sp|Q05015|FSH2_YEAST Family of serine hydrolases 2 OS=Saccharomyces cerevisiae
GN=FSH2 PE=1 SV=1
Length = 223
Score = 57 bits (135), Expect = 2e-007
Identities = 40/139 (28%), Positives = 66/139 (47%), Gaps = 15/139 (10%)
Frame = +2
Query: 218 PKSVIDRLDLVFLDAPFPCQGKSDVEGIFDPPYYEWFQFNKEFNEYTNFENCLEYLEDSM 397
P V D L V DAP G + G+ W + + Y + ++YL + +
Sbjct: 47 PADVPDFLGEVIADAP----GDGENTGVL-----AWLENDPSTGGYFIPQTTIDYLHNYV 97
Query: 398 IKLGPFDGLIGFSQGAILSGGLP----GLQARGIALQKVPKIKFIIIIGGAMFKSTKVAK 565
++ GPF G++GFSQGA ++G L GL G+ ++ P ++F + + G F+ + +
Sbjct: 98 LENGPFAGIVGFSQGAGVAGYLATDFNGL--LGLTTEEQPPLEFFMAVSGFRFQPQQYQE 155
Query: 566 DAYSSTMDTPSLHFLGETD 622
+ PSLH GE D
Sbjct: 156 QYDLHPISVPSLHVQGELD 174
>sp|Q9D7E3|OVCA2_MOUSE Ovarian cancer-associated gene 2 protein homolog OS=Mus
musculus GN=Ovca2 PE=2 SV=1
Length = 225
Score = 56 bits (133), Expect = 4e-007
Identities = 40/123 (32%), Positives = 58/123 (47%), Gaps = 5/123 (4%)
Frame = +2
Query: 269 PCQGKSDVEG-IFDPPYYEWFQFNKEFNEYTNFENCLEYLEDSMIKLGPFDGLIGFSQGA 445
PC + G F + F +E + LE + ++ LGPFDGL+GFSQGA
Sbjct: 63 PCSPEEQPRGWWFSEEEADVFSALEESTVCRGLQEALETVARALDTLGPFDGLLGFSQGA 122
Query: 446 ILSGGLPGLQARGIALQKVPKIKFIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETDF 625
L+ + L G + P +FII++ G F + + S M PSLH G+TD
Sbjct: 123 ALAAYVCALGQAGD--PRFPLPRFIILVSG--FCPRGLKEPILQSPMSLPSLHVFGDTDR 178
Query: 626 LKP 634
+ P
Sbjct: 179 VIP 181
>sp|A4II73|OVCA2_XENTR Ovarian cancer-associated gene 2 protein homolog
OS=Xenopus tropicalis GN=ovca2 PE=2 SV=2
Length = 230
Score = 55 bits (131), Expect = 6e-007
Identities = 37/107 (34%), Positives = 52/107 (48%), Gaps = 4/107 (3%)
Frame = +2
Query: 302 FDPPYYEWFQFNKEFNEYTNFENCLEYLEDSMIKLGPFDGLIGFSQGAILSGGLPGLQAR 481
F P F +E + E L+ + + +LGPFDG++GFSQGA L + L+ +
Sbjct: 80 FSNPEQNSFDAMEESKTCSGLEAPLDTVAKAFSELGPFDGILGFSQGAALVAIICALKQQ 139
Query: 482 GIALQKVPKIKFIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETD 622
G F I++ G ST AK Y + PSLH +GETD
Sbjct: 140 G---DPRFHFDFAILVAGFKSLSTDHAKH-YQQPITVPSLHVIGETD 182
>sp|Q8WZ82|OVCA2_HUMAN Ovarian cancer-associated gene 2 protein OS=Homo sapiens
GN=OVCA2 PE=1 SV=1
Length = 227
Score = 53 bits (125), Expect = 3e-006
Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
Frame = +2
Query: 365 ENCLEYLEDSMIKLGPFDGLIGFSQGAILSGGLPGLQARGIALQKVPKIKFIIIIGGAMF 544
E L + ++ +LGPFDGL+GFSQGA L+ + L G + P +FI+++ G
Sbjct: 96 EESLGMVAQALNRLGPFDGLLGFSQGAALAALVCALGQAGD--PRFPLPRFILLVSGFCP 153
Query: 545 KSTKVAKDAYSSTMDTPSLHFLGETDFLKP 634
+ + + PSLH G+TD + P
Sbjct: 154 RGIGFKESILQRPLSLPSLHVFGDTDKVIP 183
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,851,905,190
Number of Sequences: 518415
Number of Extensions: 48851905190
Number of Successful Extensions: 346316827
Number of sequences better than 0.0: 0
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