BLASTX 7.6.2
Query= UN11770 /QuerySize=948
(947 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O22785|PR19B_ARATH Pre-mRNA-processing factor 19 homolog 2 OS... 478 3e-134
sp|Q94BR4|PR19A_ARATH Pre-mRNA-processing factor 19 homolog 1 OS... 431 4e-120
sp|Q08E38|PRP19_BOVIN Pre-mRNA-processing factor 19 OS=Bos tauru... 184 1e-045
sp|Q9UMS4|PRP19_HUMAN Pre-mRNA-processing factor 19 OS=Homo sapi... 184 1e-045
sp|Q99KP6|PRP19_MOUSE Pre-mRNA-processing factor 19 OS=Mus muscu... 183 3e-045
sp|Q9JMJ4|PRP19_RAT Pre-mRNA-processing factor 19 OS=Rattus norv... 183 3e-045
sp|Q5ZMA2|PRP19_CHICK Pre-mRNA-processing factor 19 OS=Gallus ga... 169 2e-041
sp|Q7KWK5|PRP19_DICDI Pre-mRNA-processing factor 19 homolog OS=D... 167 2e-040
sp|Q10051|PRP19_CAEEL Pre-mRNA-processing factor 19 homolog OS=C... 129 3e-029
sp|O14011|CWF8_SCHPO Cell cycle control protein cwf8 OS=Schizosa... 127 1e-028
sp|P32523|PRP19_YEAST Pre-mRNA-splicing factor 19 OS=Saccharomyc... 61 9e-009
>sp|O22785|PR19B_ARATH Pre-mRNA-processing factor 19 homolog 2 OS=Arabidopsis
thaliana GN=PRP19B PE=1 SV=3
Length = 525
Score = 478 bits (1229), Expect = 3e-134
Identities = 239/257 (92%), Positives = 247/257 (96%)
Frame = +2
Query: 176 MNCAISGEVPEVPVVSTKSGLLFERRLIESHISDYGKCPVTGEPLTIDDIVPIKSGKVIK 355
MNCAISGEVP PVVSTKSGLLFERRLIE HISDYGKCPVTGEPLTIDDIVPIK+G++IK
Sbjct: 1 MNCAISGEVPVEPVVSTKSGLLFERRLIERHISDYGKCPVTGEPLTIDDIVPIKTGEIIK 60
Query: 356 PKLLHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKK 535
PK LHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKK
Sbjct: 61 PKTLHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKK 120
Query: 536 ERDEARQLLAEVDRHIPASTEAVTANAPLSNGKRAAGDEETGPDAKKLCPGISADIITEL 715
ERDEARQLLAEV+RHIPA+ EAVTANA LSNGKRAA DEE GPDAKKLCPGISA+IITEL
Sbjct: 121 ERDEARQLLAEVERHIPAAPEAVTANAALSNGKRAAVDEELGPDAKKLCPGISAEIITEL 180
Query: 716 TDCNAALSQKRKKRQIPETLASIDALGRFTQLSSHPLHKTNKPGICSMDILHSKDVIATG 895
TDCNAALSQKRKKRQIP+TLASID L RFTQLSSHPLHKTNKPGICSMDILHSKDVIATG
Sbjct: 181 TDCNAALSQKRKKRQIPQTLASIDTLERFTQLSSHPLHKTNKPGICSMDILHSKDVIATG 240
Query: 896 GVDATAVIFDRPSGQIL 946
GVDATAV+FDRPSGQIL
Sbjct: 241 GVDATAVLFDRPSGQIL 257
>sp|Q94BR4|PR19A_ARATH Pre-mRNA-processing factor 19 homolog 1 OS=Arabidopsis
thaliana GN=PRP19A PE=1 SV=1
Length = 523
Score = 431 bits (1107), Expect = 4e-120
Identities = 211/257 (82%), Positives = 235/257 (91%)
Frame = +2
Query: 176 MNCAISGEVPEVPVVSTKSGLLFERRLIESHISDYGKCPVTGEPLTIDDIVPIKSGKVIK 355
MNCAISGEVPE PVVS KSGLL+E+RLI++HISDYGKCPVTGEP T+DDIVPIK+GK++K
Sbjct: 1 MNCAISGEVPEEPVVSKKSGLLYEKRLIQTHISDYGKCPVTGEPHTLDDIVPIKTGKIVK 60
Query: 356 PKLLHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKK 535
PK LHTASIPGLLGTFQ EWD LMLSNFALEQQLHTARQELSHALYQHD+ACRVIARLKK
Sbjct: 61 PKPLHTASIPGLLGTFQTEWDSLMLSNFALEQQLHTARQELSHALYQHDAACRVIARLKK 120
Query: 536 ERDEARQLLAEVDRHIPASTEAVTANAPLSNGKRAAGDEETGPDAKKLCPGISADIITEL 715
ERDE+RQLLAE +R +PA+ E T+NA LSNGKR D E GP+AKK+ GISA++ITEL
Sbjct: 121 ERDESRQLLAEAERQLPAAPEVATSNAALSNGKRGIDDGEQGPNAKKMRLGISAEVITEL 180
Query: 716 TDCNAALSQKRKKRQIPETLASIDALGRFTQLSSHPLHKTNKPGICSMDILHSKDVIATG 895
TDCNAALSQ+RKKRQIP+TLAS+DAL +FTQLSSHPLHKTNKPGI SMDILHSKDVIATG
Sbjct: 181 TDCNAALSQQRKKRQIPKTLASVDALEKFTQLSSHPLHKTNKPGIFSMDILHSKDVIATG 240
Query: 896 GVDATAVIFDRPSGQIL 946
G+D TAV+FDRPSGQIL
Sbjct: 241 GIDTTAVLFDRPSGQIL 257
>sp|Q08E38|PRP19_BOVIN Pre-mRNA-processing factor 19 OS=Bos taurus GN=PRPF19
PE=2 SV=1
Length = 504
Score = 184 bits (465), Expect = 1e-045
Identities = 112/268 (41%), Positives = 156/268 (58%), Gaps = 28/268 (10%)
Frame = +2
Query: 182 CAISGEVPEVPVVSTKSGLLFERRLIESHISDYGKCPVTGEPLTIDDIVPIKSGKVIKPK 361
C+IS EVPE P VS S ++ERRLIE +I++ G P+ +PL+ + ++ IK I+PK
Sbjct: 5 CSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHPIRPK 64
Query: 362 LLHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKKER 541
SIP +L Q+EWD +ML +F L QQL T RQELSHALYQHD+ACRVIARL KE
Sbjct: 65 PPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARLTKEV 124
Query: 542 DEARQLLAE--------VDRHIPASTEAVT-ANAPLSNGKRAAGDEETGPDAKKLCPGIS 694
AR+ LA V + +P+S +V A P+ G+ G++
Sbjct: 125 TAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELV---------------GMT 169
Query: 695 ADIITELTDCNAALSQKRKKR--QIPETLASIDALGRFTQLSSH-PLHKTNKPGICSMDI 865
+II +L D L+ +RKKR +PE L + L ++ Q++SH LH + PGI ++D+
Sbjct: 170 PEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDL 229
Query: 866 LHS-KDVIATGGVDATAVIFDRPSGQIL 946
S + I TGG D V+FD+ S QIL
Sbjct: 230 CPSDTNKILTGGADKNVVVFDKSSEQIL 257
>sp|Q9UMS4|PRP19_HUMAN Pre-mRNA-processing factor 19 OS=Homo sapiens GN=PRPF19
PE=1 SV=1
Length = 504
Score = 184 bits (465), Expect = 1e-045
Identities = 112/268 (41%), Positives = 156/268 (58%), Gaps = 28/268 (10%)
Frame = +2
Query: 182 CAISGEVPEVPVVSTKSGLLFERRLIESHISDYGKCPVTGEPLTIDDIVPIKSGKVIKPK 361
C+IS EVPE P VS S ++ERRLIE +I++ G P+ +PL+ + ++ IK I+PK
Sbjct: 5 CSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHPIRPK 64
Query: 362 LLHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKKER 541
SIP +L Q+EWD +ML +F L QQL T RQELSHALYQHD+ACRVIARL KE
Sbjct: 65 PPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARLTKEV 124
Query: 542 DEARQLLAE--------VDRHIPASTEAVT-ANAPLSNGKRAAGDEETGPDAKKLCPGIS 694
AR+ LA V + +P+S +V A P+ G+ G++
Sbjct: 125 TAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELV---------------GMT 169
Query: 695 ADIITELTDCNAALSQKRKKR--QIPETLASIDALGRFTQLSSH-PLHKTNKPGICSMDI 865
+II +L D L+ +RKKR +PE L + L ++ Q++SH LH + PGI ++D+
Sbjct: 170 PEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDL 229
Query: 866 LHS-KDVIATGGVDATAVIFDRPSGQIL 946
S + I TGG D V+FD+ S QIL
Sbjct: 230 CPSDTNKILTGGADKNVVVFDKSSEQIL 257
>sp|Q99KP6|PRP19_MOUSE Pre-mRNA-processing factor 19 OS=Mus musculus GN=Prpf19
PE=2 SV=1
Length = 504
Score = 183 bits (462), Expect = 3e-045
Identities = 111/268 (41%), Positives = 156/268 (58%), Gaps = 28/268 (10%)
Frame = +2
Query: 182 CAISGEVPEVPVVSTKSGLLFERRLIESHISDYGKCPVTGEPLTIDDIVPIKSGKVIKPK 361
C+IS EVPE P VS S ++ERRLIE +I++ G P+ +PL+ + ++ IK I+PK
Sbjct: 5 CSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHPIRPK 64
Query: 362 LLHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKKER 541
SIP +L Q+EWD +ML +F L QQL T RQELSHALYQHD+ACRVIARL KE
Sbjct: 65 PPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARLTKEV 124
Query: 542 DEARQLLAE--------VDRHIPASTEAVT-ANAPLSNGKRAAGDEETGPDAKKLCPGIS 694
AR+ LA V + +P+S +V A P+ G+ G++
Sbjct: 125 TAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELV---------------GMT 169
Query: 695 ADIITELTDCNAALSQKRKKR--QIPETLASIDALGRFTQLSSH-PLHKTNKPGICSMDI 865
+II +L D L+ +RKKR +PE L + L ++ Q++SH LH + PGI ++D+
Sbjct: 170 PEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDL 229
Query: 866 LHS-KDVIATGGVDATAVIFDRPSGQIL 946
S + I TGG D V+FD+ + QIL
Sbjct: 230 CPSDTNKILTGGADKNVVVFDKSTEQIL 257
>sp|Q9JMJ4|PRP19_RAT Pre-mRNA-processing factor 19 OS=Rattus norvegicus
GN=Prpf19 PE=2 SV=2
Length = 504
Score = 183 bits (462), Expect = 3e-045
Identities = 111/268 (41%), Positives = 156/268 (58%), Gaps = 28/268 (10%)
Frame = +2
Query: 182 CAISGEVPEVPVVSTKSGLLFERRLIESHISDYGKCPVTGEPLTIDDIVPIKSGKVIKPK 361
C+IS EVPE P VS S ++ERRLIE +I++ G P+ +PL+ + ++ IK I+PK
Sbjct: 5 CSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHPIRPK 64
Query: 362 LLHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKKER 541
SIP +L Q+EWD +ML +F L QQL T RQELSHALYQHD+ACRVIARL KE
Sbjct: 65 PPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARLTKEV 124
Query: 542 DEARQLLAE--------VDRHIPASTEAVT-ANAPLSNGKRAAGDEETGPDAKKLCPGIS 694
AR+ LA V + +P+S +V A P+ G+ G++
Sbjct: 125 TAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELV---------------GMT 169
Query: 695 ADIITELTDCNAALSQKRKKR--QIPETLASIDALGRFTQLSSH-PLHKTNKPGICSMDI 865
+II +L D L+ +RKKR +PE L + L ++ Q++SH LH + PGI ++D+
Sbjct: 170 PEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDL 229
Query: 866 LHS-KDVIATGGVDATAVIFDRPSGQIL 946
S + I TGG D V+FD+ + QIL
Sbjct: 230 CPSDTNKILTGGADKNVVVFDKSTEQIL 257
>sp|Q5ZMA2|PRP19_CHICK Pre-mRNA-processing factor 19 OS=Gallus gallus GN=PRPF19
PE=1 SV=1
Length = 505
Score = 169 bits (428), Expect = 2e-041
Identities = 110/262 (41%), Positives = 149/262 (56%), Gaps = 15/262 (5%)
Frame = +2
Query: 182 CAISGEVPEVPVVSTKSGLLFERRLIESHISDYGKCPVTGEPLTIDDIVPIKSGKVIKPK 361
C+IS EVPE P VS S ++ERRLIE +I++ G PV +PL+ + ++ IK I+P+
Sbjct: 5 CSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPVNNQPLSEEQLIDIKVAHPIRPR 64
Query: 362 LLHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKKER 541
SIP +L Q+EWD +ML +F L QQL T RQELSHALYQHD+ACRVIARL KE
Sbjct: 65 PPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARLTKEV 124
Query: 542 DEARQLLAEVDRHIPASTEAVTANAPLSNGKRAAGDEETGPDAKKLCPGISADIITELTD 721
AR+ LA + P + V P S A E D +L G++ +II + D
Sbjct: 125 TAAREALATLK---PQAGLIVPQAVPSSQPNVAGAGESM--DLGELA-GMTPEIIQKPQD 178
Query: 722 CNAALSQKRKKR--QIPETLASIDALGRFTQLSSHP----LHKTNKPGICSMDILHS-KD 880
L+ +RKKR +PE L ++A G P LH + PGI ++D+ S +
Sbjct: 179 KATVLTTERKKRGKTVPEEL--VEARGAQQVPGRSPRMWGLHSASIPGILALDLCPSDTN 236
Query: 881 VIATGGVDATAVIFDRPSGQIL 946
I TGG D ++FD+ S QIL
Sbjct: 237 KILTGGADKNVIVFDKSSEQIL 258
>sp|Q7KWK5|PRP19_DICDI Pre-mRNA-processing factor 19 homolog OS=Dictyostelium
discoideum GN=prp19 PE=3 SV=1
Length = 514
Score = 167 bits (421), Expect = 2e-040
Identities = 97/260 (37%), Positives = 143/260 (55%), Gaps = 13/260 (5%)
Frame = +2
Query: 176 MNCAISGEVPEVPVVSTKSGLLFERRLIESHISDYGKCPVTGEPLTIDDIVPIKSGKVIK 355
M CAISG E PV+STK+G ++E+RLIE +I GK P TGEPL + D++ +K GK +K
Sbjct: 1 MICAISGSTTEEPVISTKTGNVYEKRLIEKYIDTNGKEPTTGEPLGLSDLITVKIGKTVK 60
Query: 356 PKLLHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKK 535
P+ SIP +L FQNEWD LML F L+QQ T RQEL+H++YQ+D+ACRVIARL K
Sbjct: 61 PRPTTATSIPSMLQLFQNEWDSLMLETFTLKQQHETVRQELAHSMYQYDAACRVIARLVK 120
Query: 536 ERDEARQLLAEVDRHIPASTEAVTANAPLSNGKRAAGDEETGPDAKKLCPGISADIITEL 715
ERD AR LA + + N +N K + P + + + + I +
Sbjct: 121 ERDAARSALANARNIVQQQQQQTNNNNNNNNNKDVEMSSASTPSSSE-DNLLDSTIYKRI 179
Query: 716 TDCNAALSQKRKKRQIPETLASIDALGRFTQLSSHPLHKTNKPGICSMDIL----HSKDV 883
+ + L + RK+R ++LA DA+ +F N C + L ++
Sbjct: 180 AEKSEELIKTRKER-THQSLAEPDAIKQFKV-------SANVETDCQIKSLEVNSQDNNL 231
Query: 884 IATGGVDATAVIFDRPSGQI 943
IA GG++ ++ R + ++
Sbjct: 232 IAMGGINGNVYVYSRETNEL 251
>sp|Q10051|PRP19_CAEEL Pre-mRNA-processing factor 19 homolog OS=Caenorhabditis
elegans GN=T10F2.4 PE=2 SV=2
Length = 492
Score = 129 bits (323), Expect = 3e-029
Identities = 69/140 (49%), Positives = 93/140 (66%), Gaps = 1/140 (0%)
Frame = +2
Query: 182 CAISGEVPEVPVVSTKSGLLFERRLIESHISDYGKCPVTGEPLTIDDIVPIKSGKV-IKP 358
C ISGE+ E PVVS SG +F+RRLI I++ G P++ L+ D +V +KSG P
Sbjct: 5 CGISGELTEDPVVSQVSGHIFDRRLIVKFIAENGTDPISHGELSEDQLVSLKSGGTGSAP 64
Query: 359 KLLHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKKE 538
+ + SIP LL Q+EWD +ML++F+L QQL ARQELSH+LYQHD+ACRVI+RL KE
Sbjct: 65 RNVSGTSIPSLLKMLQDEWDTVMLNSFSLRQQLQIARQELSHSLYQHDAACRVISRLSKE 124
Query: 539 RDEARQLLAEVDRHIPASTE 598
AR+ L+ + H A +
Sbjct: 125 LTAAREALSTLKPHTSAKVD 144
>sp|O14011|CWF8_SCHPO Cell cycle control protein cwf8 OS=Schizosaccharomyces
pombe GN=cwf8 PE=1 SV=1
Length = 488
Score = 127 bits (318), Expect = 1e-028
Identities = 65/136 (47%), Positives = 89/136 (65%)
Frame = +2
Query: 176 MNCAISGEVPEVPVVSTKSGLLFERRLIESHISDYGKCPVTGEPLTIDDIVPIKSGKVIK 355
M C+ISGE P+ PV+S SG ++E+RLIE I + K PVT + T++D+VP+K ++
Sbjct: 1 MFCSISGETPKEPVISRVSGNVYEKRLIEQVIRETSKDPVTQQECTLEDLVPVKVPDFVR 60
Query: 356 PKLLHTASIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKK 535
P+ S+P LL FQ EWD + L F L + L +QELS ALY D+A RVI+RL K
Sbjct: 61 PRPPSATSLPALLSLFQEEWDSVALEQFELRRNLTETKQELSTALYSLDAALRVISRLTK 120
Query: 536 ERDEARQLLAEVDRHI 583
ERDEAR+ LA+ +I
Sbjct: 121 ERDEAREALAKFSDNI 136
>sp|P32523|PRP19_YEAST Pre-mRNA-splicing factor 19 OS=Saccharomyces cerevisiae
GN=PRP19 PE=1 SV=2
Length = 503
Score = 61 bits (147), Expect = 9e-009
Identities = 28/53 (52%), Positives = 39/53 (73%)
Frame = +2
Query: 176 MNCAISGEVPEVPVVSTKSGLLFERRLIESHISDYGKCPVTGEPLTIDDIVPI 334
M CAISG+VP PV+S KS +FE+ L+E ++ D G P+T EPL+I++IV I
Sbjct: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEI 53
Score = 55 bits (130), Expect = 8e-007
Identities = 29/73 (39%), Positives = 43/73 (58%)
Frame = +2
Query: 377 SIPGLLGTFQNEWDGLMLSNFALEQQLHTARQELSHALYQHDSACRVIARLKKERDEARQ 556
SIP LL + QNEWD +ML NF L L + ++LS +Y+ D+A V A+L E++E +
Sbjct: 76 SIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAAKLVAAQLLMEKNEDSK 135
Query: 557 LLAEVDRHIPAST 595
L + + A T
Sbjct: 136 DLPKSSQQAVAIT 148
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,851,905,190
Number of Sequences: 518415
Number of Extensions: 48851905190
Number of Successful Extensions: 346316827
Number of sequences better than 0.0: 0
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