BLASTX 7.6.2
Query= UN11939 /QuerySize=1254
(1253 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos ... 88 1e-016
sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo... 87 2e-016
sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo... 86 4e-016
sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus ... 85 1e-015
sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN... 84 1e-015
sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN... 83 4e-015
sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=R... 82 6e-015
sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 82 7e-015
sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 81 2e-014
sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 81 2e-014
sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus ... 81 2e-014
sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus... 81 2e-014
sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Dani... 80 3e-014
sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Dros... 77 2e-013
sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabido... 75 1e-012
sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabido... 74 2e-012
sp|Q8NG27|PJA1_HUMAN E3 ubiquitin-protein ligase Praja-1 OS=Homo... 67 2e-010
sp|O55176|PJA1_MOUSE E3 ubiquitin-protein ligase Praja-1 OS=Mus ... 67 2e-010
sp|Q9C1X4|YKW3_SCHPO Uncharacterized RING finger protein P32A8.0... 63 3e-009
sp|Q9H9V4|RN122_HUMAN RING finger protein 122 OS=Homo sapiens GN... 60 4e-008
>sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos taurus
GN=RNF181 PE=2 SV=1
Length = 153
Score = 88 bits (216), Expect = 1e-016
Identities = 44/95 (46%), Positives = 56/95 (58%), Gaps = 3/95 (3%)
Frame = +3
Query: 621 PARKEAVENLPTVKV---CEPLQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWLELHSS 791
PA K AVENLP + L+C VCL +FE+ A EMPC H FH+ CI+PWL +S
Sbjct: 53 PAAKTAVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSNCILPWLSKTNS 112
Query: 792 CPVCRYELPPDDEVKADLVRPTTRSVGVNLRNENV 896
CP+CR+ELP DD+ + R R R EN+
Sbjct: 113 CPLCRHELPTDDDTYEEHKRDKARKQQQKHRLENL 147
>sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo sapiens
GN=RNF181 PE=1 SV=1
Length = 153
Score = 87 bits (215), Expect = 2e-016
Identities = 44/95 (46%), Positives = 55/95 (57%), Gaps = 3/95 (3%)
Frame = +3
Query: 621 PARKEAVENLPTVKV---CEPLQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWLELHSS 791
PA K VENLP + L+C VCL +FE+ A EMPC H FH+ CI+PWL +S
Sbjct: 53 PAAKTVVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTNS 112
Query: 792 CPVCRYELPPDDEVKADLVRPTTRSVGVNLRNENV 896
CP+CRYELP DD+ + R R R EN+
Sbjct: 113 CPLCRYELPTDDDTYEEHRRDKARKQQQQHRLENL 147
>sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo sapiens
GN=RNF115 PE=1 SV=2
Length = 304
Score = 86 bits (212), Expect = 4e-016
Identities = 43/106 (40%), Positives = 60/106 (56%), Gaps = 8/106 (7%)
Frame = +3
Query: 537 GDYL-ARPEFDSLLRNLADNDLIRRQGTLPARKEAVENLPTVKVCEP-----LQCSVCLE 698
GDY + D+++ L + G PA KE + +LPTV V + L+C VC E
Sbjct: 176 GDYAWGQTGLDAIVTQLLGQ--LENTGPPPADKEKITSLPTVTVTQEQVDMGLECPVCKE 233
Query: 699 DFEKGSEAKEMPCKHKFHNRCIVPWLELHSSCPVCRYELPPDDEVK 836
D+ E +++PC H FH+ CIVPWLELH +CPVCR L +D +
Sbjct: 234 DYTVEEEVRQLPCNHFFHSSCIVPWLELHDTCPVCRKSLNGEDSTR 279
>sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus musculus
GN=Rnf115 PE=1 SV=1
Length = 305
Score = 85 bits (208), Expect = 1e-015
Identities = 42/106 (39%), Positives = 60/106 (56%), Gaps = 8/106 (7%)
Frame = +3
Query: 537 GDYL-ARPEFDSLLRNLADNDLIRRQGTLPARKEAVENLPTVKVCEP-----LQCSVCLE 698
GDY + D+++ L + G PA KE + +LPTV V + L+C VC E
Sbjct: 177 GDYAWGQTGLDAIVTQLLGQ--LENTGPPPADKEKITSLPTVTVTQEQVNTGLECPVCKE 234
Query: 699 DFEKGSEAKEMPCKHKFHNRCIVPWLELHSSCPVCRYELPPDDEVK 836
D+ + +++PC H FH+ CIVPWLELH +CPVCR L +D +
Sbjct: 235 DYTVEEKVRQLPCNHFFHSSCIVPWLELHDTCPVCRKSLNGEDSTR 280
>sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN=Rnf126 PE=1
SV=1
Length = 313
Score = 84 bits (207), Expect = 1e-015
Identities = 38/73 (52%), Positives = 46/73 (63%), Gaps = 5/73 (6%)
Frame = +3
Query: 612 GTLPARKEAVENLPTVKVCEP-----LQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWL 776
G PA KE ++ LPTV V E L+C VC ED+ G +++PC H FH+ CIVPWL
Sbjct: 203 GPPPADKEKIQALPTVPVTEEHVGSGLECPVCKEDYALGESVRQLPCNHLFHDSCIVPWL 262
Query: 777 ELHSSCPVCRYEL 815
E H SCPVCR L
Sbjct: 263 EQHDSCPVCRKSL 275
>sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN=RNF126 PE=1
SV=1
Length = 326
Score = 83 bits (203), Expect = 4e-015
Identities = 37/73 (50%), Positives = 46/73 (63%), Gaps = 5/73 (6%)
Frame = +3
Query: 612 GTLPARKEAVENLPTVKVCEP-----LQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWL 776
G PA KE ++ LPTV V E L+C VC +D+ G +++PC H FH+ CIVPWL
Sbjct: 201 GPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYALGERVRQLPCNHLFHDGCIVPWL 260
Query: 777 ELHSSCPVCRYEL 815
E H SCPVCR L
Sbjct: 261 EQHDSCPVCRKSL 273
>sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=RNF126 PE=2
SV=1
Length = 313
Score = 82 bits (202), Expect = 6e-015
Identities = 37/73 (50%), Positives = 46/73 (63%), Gaps = 5/73 (6%)
Frame = +3
Query: 612 GTLPARKEAVENLPTVKVCEP-----LQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWL 776
G PA KE ++ LPTV V E L+C VC +D+ G +++PC H FH+ CIVPWL
Sbjct: 204 GPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYGLGEHVRQLPCNHLFHDGCIVPWL 263
Query: 777 ELHSSCPVCRYEL 815
E H SCPVCR L
Sbjct: 264 EQHDSCPVCRKSL 276
>sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126
PE=2 SV=1
Length = 311
Score = 82 bits (201), Expect = 7e-015
Identities = 34/73 (46%), Positives = 46/73 (63%), Gaps = 5/73 (6%)
Frame = +3
Query: 612 GTLPARKEAVENLPTVKVCEP-----LQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWL 776
G PA E ++ LPT+++ E L+C VC ED+ G +++PC H FHN CI+PWL
Sbjct: 199 GPPPADTEKIQALPTIQITEEHVGSGLECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWL 258
Query: 777 ELHSSCPVCRYEL 815
E H +CPVCR L
Sbjct: 259 EQHDTCPVCRKSL 271
>sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-a
PE=2 SV=1
Length = 312
Score = 81 bits (198), Expect = 2e-014
Identities = 34/73 (46%), Positives = 46/73 (63%), Gaps = 5/73 (6%)
Frame = +3
Query: 612 GTLPARKEAVENLPTVKVCEP-----LQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWL 776
G PA E ++ LPT+++ E L+C VC ED+ G +++PC H FHN CI+PWL
Sbjct: 200 GPPPADNEKIQALPTIQITEEHVGSGLECPVCKEDYTVGECVRQLPCNHLFHNDCIIPWL 259
Query: 777 ELHSSCPVCRYEL 815
E H +CPVCR L
Sbjct: 260 EQHDTCPVCRKSL 272
>sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-b
PE=2 SV=1
Length = 312
Score = 81 bits (198), Expect = 2e-014
Identities = 33/73 (45%), Positives = 46/73 (63%), Gaps = 5/73 (6%)
Frame = +3
Query: 612 GTLPARKEAVENLPTVKVCEP-----LQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWL 776
G PA + ++ LPT+++ E L+C VC ED+ G +++PC H FHN CI+PWL
Sbjct: 200 GPPPADTDKIQALPTIQITEEHVGFGLECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWL 259
Query: 777 ELHSSCPVCRYEL 815
E H +CPVCR L
Sbjct: 260 EQHDTCPVCRKSL 272
>sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus musculus
GN=Rnf181 PE=2 SV=1
Length = 165
Score = 81 bits (198), Expect = 2e-014
Identities = 40/95 (42%), Positives = 53/95 (55%), Gaps = 3/95 (3%)
Frame = +3
Query: 621 PARKEAVENLPTVKVCE---PLQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWLELHSS 791
PA K VE+LP + L+C VCL +FE EMPC H FH+ CI+PWL +S
Sbjct: 65 PAAKAVVESLPRTVISSAKADLKCPVCLLEFEAEETVIEMPCHHLFHSNCILPWLSKTNS 124
Query: 792 CPVCRYELPPDDEVKADLVRPTTRSVGVNLRNENV 896
CP+CR+ELP DD+ + + R R EN+
Sbjct: 125 CPLCRHELPTDDDSYEEHKKDKARRQQQQHRLENL 159
>sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus norvegicus
GN=Rnf181 PE=1 SV=1
Length = 165
Score = 81 bits (198), Expect = 2e-014
Identities = 40/95 (42%), Positives = 54/95 (56%), Gaps = 3/95 (3%)
Frame = +3
Query: 621 PARKEAVENLPTVKVCE---PLQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWLELHSS 791
PA K VE+LP + L+C VCL +FE+ EMPC H FH+ CI+PWL +S
Sbjct: 65 PAAKAVVESLPRTVIRSSKAELKCPVCLLEFEEEETVIEMPCHHLFHSNCILPWLSKTNS 124
Query: 792 CPVCRYELPPDDEVKADLVRPTTRSVGVNLRNENV 896
CP+CR+ELP DD+ + + R R EN+
Sbjct: 125 CPLCRHELPTDDDSYEEHKKDKARRQQQQHRLENL 159
>sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Danio rerio
GN=rnf181 PE=2 SV=2
Length = 156
Score = 80 bits (196), Expect = 3e-014
Identities = 40/90 (44%), Positives = 53/90 (58%), Gaps = 9/90 (10%)
Frame = +3
Query: 621 PARKEAVENLPTVKVC-----EPLQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWLELH 785
PA K V++LP V + + ++C VCL +FE+ +EMPCKH FH CI+PWL
Sbjct: 54 PAAKAVVQSLPVVIISPEQADKGVKCPVCLLEFEEQESVREMPCKHLFHTGCILPWLNKT 113
Query: 786 SSCPVCRYELPPD----DEVKADLVRPTTR 863
+SCP+CR ELP D +E K D R R
Sbjct: 114 NSCPLCRLELPTDNADYEEFKKDKERRRQR 143
>sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Drosophila
melanogaster GN=CG7694 PE=2 SV=1
Length = 147
Score = 77 bits (188), Expect = 2e-013
Identities = 36/81 (44%), Positives = 51/81 (62%), Gaps = 5/81 (6%)
Frame = +3
Query: 624 ARKEAVENLPTVKVCE-----PLQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWLELHS 788
A K A+ LP ++ + L+CSVC E E+G + + +PCKH+FH CI+ WL+ +
Sbjct: 46 ASKRAILELPVHEIVKSDEGGDLECSVCKEPAEEGQKYRILPCKHEFHEECILLWLKKTN 105
Query: 789 SCPVCRYELPPDDEVKADLVR 851
SCP+CRYEL DD V +L R
Sbjct: 106 SCPLCRYELETDDPVYEELRR 126
>sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabidopsis thaliana
GN=CIP8 PE=1 SV=1
Length = 334
Score = 75 bits (182), Expect = 1e-012
Identities = 34/79 (43%), Positives = 46/79 (58%), Gaps = 5/79 (6%)
Frame = +3
Query: 606 RQGTLPARKEAVENLPTVKVCEP-----LQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVP 770
R+G PA K A+E L T +V + C+VC + G K++PC H +H CIVP
Sbjct: 227 RRGAPPAAKSAIEALETFEVSSSEGEMVMVCAVCKDGMVMGETGKKLPCGHCYHGDCIVP 286
Query: 771 WLELHSSCPVCRYELPPDD 827
WL +SCPVCR++L DD
Sbjct: 287 WLGTRNSCPVCRFQLETDD 305
>sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabidopsis thaliana
GN=AIP2 PE=1 SV=1
Length = 310
Score = 74 bits (180), Expect = 2e-012
Identities = 26/51 (50%), Positives = 38/51 (74%)
Frame = +3
Query: 678 QCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWLELHSSCPVCRYELPPDDE 830
+C +C E+ G + +E+PCKH FH C+ PWL+ H+SCP+CR+ELP DD+
Sbjct: 229 ECCICKENLVIGDKMQELPCKHTFHPPCLKPWLDEHNSCPICRHELPTDDQ 279
>sp|Q8NG27|PJA1_HUMAN E3 ubiquitin-protein ligase Praja-1 OS=Homo sapiens
GN=PJA1 PE=1 SV=2
Length = 643
Score = 67 bits (163), Expect = 2e-010
Identities = 29/74 (39%), Positives = 41/74 (55%), Gaps = 7/74 (9%)
Frame = +3
Query: 621 PARKEAVENLPTVKVCE-------PLQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWLE 779
PA KE+++ LP + V E + C +C ++ KG A E+PC H FH C+ WL+
Sbjct: 568 PASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVSIWLQ 627
Query: 780 LHSSCPVCRYELPP 821
+CPVCR PP
Sbjct: 628 KSGTCPVCRCMFPP 641
>sp|O55176|PJA1_MOUSE E3 ubiquitin-protein ligase Praja-1 OS=Mus musculus
GN=Pja1 PE=1 SV=3
Length = 578
Score = 67 bits (163), Expect = 2e-010
Identities = 29/74 (39%), Positives = 41/74 (55%), Gaps = 7/74 (9%)
Frame = +3
Query: 621 PARKEAVENLPTVKVCE-------PLQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWLE 779
PA KE+++ LP + V E + C +C ++ KG A E+PC H FH C+ WL+
Sbjct: 503 PASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVSIWLQ 562
Query: 780 LHSSCPVCRYELPP 821
+CPVCR PP
Sbjct: 563 KSGTCPVCRCMFPP 576
>sp|Q9C1X4|YKW3_SCHPO Uncharacterized RING finger protein P32A8.03c
OS=Schizosaccharomyces pombe GN=SPAP32A8.03c PE=2 SV=1
Length = 513
Score = 63 bits (152), Expect = 3e-009
Identities = 34/132 (25%), Positives = 63/132 (47%), Gaps = 5/132 (3%)
Frame = +3
Query: 630 KEAVENLPTVKVCEPLQCSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWLELHSSCPVCRY 809
K V+ P + E +C++C+E F+ + ++PCKH FH CI PWL ++ +C +CR
Sbjct: 379 KMKVQKPPKELIDEEGECTICMEMFKINDDVIQLPCKHYFHENCIKPWLRVNGTCAICRA 438
Query: 810 ELPPDDEVKADLVRPTTRSVGVNLRNENVEENARNISGSERRFSLPWPLSGLFSSSSSSS 989
+ P+ + R T + N N + N + +++ +L S S+ SS
Sbjct: 439 PVDPNSQ-----QRNNTSTDSANGHNPSNHANPSTSTTNDQGATLRNESFNAASQSNLSS 493
Query: 990 SGSTSGSSQVNE 1025
S + +++
Sbjct: 494 EHGHSSRTPMDD 505
>sp|Q9H9V4|RN122_HUMAN RING finger protein 122 OS=Homo sapiens GN=RNF122 PE=2
SV=2
Length = 155
Score = 60 bits (143), Expect = 4e-008
Identities = 22/55 (40%), Positives = 33/55 (60%)
Frame = +3
Query: 681 CSVCLEDFEKGSEAKEMPCKHKFHNRCIVPWLELHSSCPVCRYELPPDDEVKADL 845
C+VCLEDF+ E +PC+H FH +C+V WLE+ CP+C + E ++
Sbjct: 93 CAVCLEDFKGKDELGVLPCQHAFHRKCLVKWLEVRCVCPMCNKPIASPSEATQNI 147
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,851,905,190
Number of Sequences: 518415
Number of Extensions: 48851905190
Number of Successful Extensions: 346316827
Number of sequences better than 0.0: 0
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