BLASTX 7.6.2
Query= UN13054 /QuerySize=1455
(1454 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9LRS0|GOX1_ARATH Probable peroxisomal (S)-2-hydroxy-acid oxi... 700 9e-201
sp|Q9LRR9|GOX2_ARATH Probable peroxisomal (S)-2-hydroxy-acid oxi... 690 9e-198
sp|P05414|GOX_SPIOL Peroxisomal (S)-2-hydroxy-acid oxidase OS=Sp... 643 1e-183
sp|Q9UJM8|HAOX1_HUMAN Hydroxyacid oxidase 1 OS=Homo sapiens GN=H... 399 2e-110
sp|Q9WU19|HAOX1_MOUSE Hydroxyacid oxidase 1 OS=Mus musculus GN=H... 393 2e-108
sp|Q54E41|HAOX_DICDI Hydroxyacid oxidase OS=Dictyostelium discoi... 356 2e-097
sp|Q3ZBW2|HAOX2_BOVIN Hydroxyacid oxidase 2 OS=Bos taurus GN=HAO... 325 6e-088
sp|Q9NYQ3|HAOX2_HUMAN Hydroxyacid oxidase 2 OS=Homo sapiens GN=H... 309 6e-083
sp|Q07523|HAOX2_RAT Hydroxyacid oxidase 2 OS=Rattus norvegicus G... 294 2e-078
sp|Q9NYQ2|HAOX2_MOUSE Hydroxyacid oxidase 2 OS=Mus musculus GN=H... 287 2e-076
sp|Q1IF69|LLDD_PSEE4 L-lactate dehydrogenase [cytochrome] OS=Pse... 150 3e-035
sp|A5W9B2|LLDD_PSEP1 L-lactate dehydrogenase [cytochrome] OS=Pse... 149 4e-035
sp|Q88DT3|LLDD_PSEPK L-lactate dehydrogenase [cytochrome] OS=Pse... 149 4e-035
sp|B0KIT4|LLDD_PSEPG L-lactate dehydrogenase [cytochrome] OS=Pse... 149 6e-035
sp|B7V1I3|LLDD_PSEA8 L-lactate dehydrogenase [cytochrome] OS=Pse... 148 1e-034
sp|Q9HV37|LLDD_PSEAE L-lactate dehydrogenase [cytochrome] OS=Pse... 148 1e-034
sp|A6VCM8|LLDD_PSEA7 L-lactate dehydrogenase [cytochrome] OS=Pse... 147 2e-034
sp|Q02FQ1|LLDD_PSEAB L-lactate dehydrogenase [cytochrome] OS=Pse... 147 3e-034
sp|B2FIJ0|LLDD_STRMK L-lactate dehydrogenase [cytochrome] OS=Ste... 145 8e-034
sp|A8ARJ1|LLDD_CITK8 L-lactate dehydrogenase [cytochrome] OS=Cit... 144 1e-033
>sp|Q9LRS0|GOX1_ARATH Probable peroxisomal (S)-2-hydroxy-acid oxidase 1
OS=Arabidopsis thaliana GN=At3g14415 PE=1 SV=1
Length = 367
Score = 700 bits (1805), Expect = 9e-201
Identities = 354/367 (96%), Positives = 364/367 (99%)
Frame = +2
Query: 59 MEITNVTEYEAIAKEKLPKMVYDYYASGAEDQWTLKENRNAFARILFRPRILIDVSKIDM 238
MEITNVTEY+AIAK KLPKMVYDYYASGAEDQWTL+ENRNAFARILFRPRILIDV+KIDM
Sbjct: 1 MEITNVTEYDAIAKAKLPKMVYDYYASGAEDQWTLQENRNAFARILFRPRILIDVNKIDM 60
Query: 239 TTTVLGFKISMPIMVAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTG 418
TTVLGFKISMPIMVAPTA QKMAHP+GEYATARAASAAGTIMTLSSWATSSVEEVASTG
Sbjct: 61 ATTVLGFKISMPIMVAPTAFQKMAHPDGEYATARAASAAGTIMTLSSWATSSVEEVASTG 120
Query: 419 PGIRFFQLYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTL 598
PGIRFFQLYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTL
Sbjct: 121 PGIRFFQLYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTL 180
Query: 599 KNFEGLDLGKMDEANDSGLASYVAGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARI 778
KNFEGLDLGKMDEANDSGLASYVAGQIDRTLSWKD+QWLQTIT+MPILVKGVLTGEDARI
Sbjct: 181 KNFEGLDLGKMDEANDSGLASYVAGQIDRTLSWKDIQWLQTITNMPILVKGVLTGEDARI 240
Query: 779 AIQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALAL 958
AIQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALAL
Sbjct: 241 AIQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALAL 300
Query: 959 GASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIITEWET 1138
GASGIFIGRPVVF+LAAEGEAGV+KVLQMLRDEFELTMALSGCRSLSEITRNHI+TEW+T
Sbjct: 301 GASGIFIGRPVVFALAAEGEAGVKKVLQMLRDEFELTMALSGCRSLSEITRNHIVTEWDT 360
Query: 1139 PRHLPRL 1159
PRHLPRL
Sbjct: 361 PRHLPRL 367
>sp|Q9LRR9|GOX2_ARATH Probable peroxisomal (S)-2-hydroxy-acid oxidase 2
OS=Arabidopsis thaliana GN=At3g14420 PE=1 SV=1
Length = 367
Score = 690 bits (1779), Expect = 9e-198
Identities = 351/367 (95%), Positives = 360/367 (98%)
Frame = +2
Query: 59 MEITNVTEYEAIAKEKLPKMVYDYYASGAEDQWTLKENRNAFARILFRPRILIDVSKIDM 238
MEITNVTEY+AIAK+KLPKMVYDYYASGAEDQWTL+ENRNAFARILFRPRILIDVSKIDM
Sbjct: 1 MEITNVTEYDAIAKQKLPKMVYDYYASGAEDQWTLQENRNAFARILFRPRILIDVSKIDM 60
Query: 239 TTTVLGFKISMPIMVAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTG 418
TTTVLGFKISMPIMVAPTAMQKMAHP+GEYATARAASAAGTIMTLSSWATSSVEEVASTG
Sbjct: 61 TTTVLGFKISMPIMVAPTAMQKMAHPDGEYATARAASAAGTIMTLSSWATSSVEEVASTG 120
Query: 419 PGIRFFQLYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTL 598
PGIRFFQLYVYKNR VVEQLVRRAE+AGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTL
Sbjct: 121 PGIRFFQLYVYKNRNVVEQLVRRAERAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTL 180
Query: 599 KNFEGLDLGKMDEANDSGLASYVAGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARI 778
KNFEGLDLGKMDEANDSGLASYVAGQIDRTLSWKDVQWLQTIT +PILVKGVLTGEDARI
Sbjct: 181 KNFEGLDLGKMDEANDSGLASYVAGQIDRTLSWKDVQWLQTITKLPILVKGVLTGEDARI 240
Query: 779 AIQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALAL 958
AIQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGR+PVFLDGGVRRGTDVFKALAL
Sbjct: 241 AIQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRIPVFLDGGVRRGTDVFKALAL 300
Query: 959 GASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIITEWET 1138
GASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSL EI+RNHI TEW+T
Sbjct: 301 GASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLKEISRNHITTEWDT 360
Query: 1139 PRHLPRL 1159
PR RL
Sbjct: 361 PRPSARL 367
>sp|P05414|GOX_SPIOL Peroxisomal (S)-2-hydroxy-acid oxidase OS=Spinacia oleracea
PE=1 SV=1
Length = 369
Score = 643 bits (1657), Expect = 1e-183
Identities = 320/361 (88%), Positives = 345/361 (95%)
Frame = +2
Query: 59 MEITNVTEYEAIAKEKLPKMVYDYYASGAEDQWTLKENRNAFARILFRPRILIDVSKIDM 238
MEITNV EYEAIAK+KLPKMVYDYYASGAEDQWTL ENRNAF+RILFRPRILIDV+ IDM
Sbjct: 1 MEITNVNEYEAIAKQKLPKMVYDYYASGAEDQWTLAENRNAFSRILFRPRILIDVTNIDM 60
Query: 239 TTTVLGFKISMPIMVAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTG 418
TTT+LGFKISMPIM+APTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTG
Sbjct: 61 TTTILGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTG 120
Query: 419 PGIRFFQLYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTL 598
PGIRFFQLYVYK+R VV QLVRRAE+AGFKAIALTVDTPRLGRRE+DIKNRF LPP LTL
Sbjct: 121 PGIRFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLTL 180
Query: 599 KNFEGLDLGKMDEANDSGLASYVAGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARI 778
KNFEG+DLGKMD+ANDSGL+SYVAGQIDR+LSWKDV WLQTITS+PILVKGV+T EDAR+
Sbjct: 181 KNFEGIDLGKMDKANDSGLSSYVAGQIDRSLSWKDVAWLQTITSLPILVKGVITAEDARL 240
Query: 779 AIQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALAL 958
A+Q GAAGIIVSNHGARQLDYVPATI ALEEVVKA QGR+PVFLDGGVRRGTDVFKALAL
Sbjct: 241 AVQHGAAGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALAL 300
Query: 959 GASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIITEWET 1138
GA+G+FIGRPVVFSLAAEGEAGV+KVLQM+RDEFELTMALSGCRSL EI+R+HI +W+
Sbjct: 301 GAAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSGCRSLKEISRSHIAADWDG 360
Query: 1139 P 1141
P
Sbjct: 361 P 361
>sp|Q9UJM8|HAOX1_HUMAN Hydroxyacid oxidase 1 OS=Homo sapiens GN=HAO1 PE=1 SV=1
Length = 370
Score = 399 bits (1025), Expect = 2e-110
Identities = 200/350 (57%), Positives = 266/350 (76%), Gaps = 4/350 (1%)
Frame = +2
Query: 74 VTEYEAIAKEKLPKMVYDYYASGAEDQWTLKENRNAFARILFRPRILIDVSKIDMTTTVL 253
+ +YE AK LPK +YDYY SGA D+ TL +N AF+R PR+L +V++ D++T+VL
Sbjct: 8 INDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLSTSVL 67
Query: 254 GFKISMPIMVAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGP-GIR 430
G ++SMPI V TAMQ+MAH +GE AT RA + GT M LSSWATSS+EEVA GP +R
Sbjct: 68 GQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPEALR 127
Query: 431 FFQLYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTLKNFE 610
+ QLY+YK+R+V ++LVR+AEK G+KAI +TVDTP LG R D++NRF LPP L +KNFE
Sbjct: 128 WLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFE 187
Query: 611 GLDLGKMDEAN---DSGLASYVAGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIA 781
L E N DSGLA+YVA ID ++SW+D++WL+ +TS+PI+ KG+L G+DAR A
Sbjct: 188 TSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREA 247
Query: 782 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 961
++ G GI+VSNHGARQLD VPATI L E+V+A +G+V VFLDGGVR+GTDV KALALG
Sbjct: 248 VKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALG 307
Query: 962 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITR 1111
A +F+GRP+V+ LA +GE GV+ VL++L++EF L MALSGC+++ I +
Sbjct: 308 AKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDK 357
>sp|Q9WU19|HAOX1_MOUSE Hydroxyacid oxidase 1 OS=Mus musculus GN=Hao1 PE=2 SV=1
Length = 370
Score = 393 bits (1009), Expect = 2e-108
Identities = 198/350 (56%), Positives = 261/350 (74%), Gaps = 4/350 (1%)
Frame = +2
Query: 74 VTEYEAIAKEKLPKMVYDYYASGAEDQWTLKENRNAFARILFRPRILIDVSKIDMTTTVL 253
+++YE + L K VYDYY SGA DQ TL +N AF+R PR+L +V+ ID++T+VL
Sbjct: 8 ISDYEQHVRSVLQKSVYDYYRSGANDQETLADNIQAFSRWKLYPRMLRNVADIDLSTSVL 67
Query: 254 GFKISMPIMVAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGP-GIR 430
G ++SMPI V TAMQ MAH +GE AT RA GT M LSSWATSS+EEVA GP +R
Sbjct: 68 GQRVSMPICVGATAMQCMAHVDGELATVRACQTMGTGMMLSSWATSSIEEVAEAGPEALR 127
Query: 431 FFQLYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTLKNFE 610
+ QLY+YK+R++ Q+V+RAEK G+KAI +TVDTP LG R D++NRF LPP L +KNFE
Sbjct: 128 WMQLYIYKDREISRQIVKRAEKQGYKAIFVTVDTPYLGNRIDDVRNRFKLPPQLRMKNFE 187
Query: 611 GLDLGKMDEAN---DSGLASYVAGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIA 781
DL + N +SGLA YVA ID +LSW D+ WL+ +TS+PI+VKG+L G+DA+ A
Sbjct: 188 TNDLAFSPKGNFGDNSGLAEYVAQAIDPSLSWDDITWLRRLTSLPIVVKGILRGDDAKEA 247
Query: 782 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 961
++ G GI+VSNHGARQLD VPATI L E+V+A +G+V VFLDGGVR+GTDV KALALG
Sbjct: 248 VKHGVDGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALG 307
Query: 962 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITR 1111
A +F+GRP+++ LA +GE GV+ VL++L++EF L MALSGC+++ I +
Sbjct: 308 AKAVFVGRPIIWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDK 357
>sp|Q54E41|HAOX_DICDI Hydroxyacid oxidase OS=Dictyostelium discoideum GN=haox
PE=3 SV=1
Length = 388
Score = 356 bits (913), Expect = 2e-097
Identities = 186/351 (52%), Positives = 246/351 (70%), Gaps = 5/351 (1%)
Frame = +2
Query: 71 NVTEYEAIAKEKLPKMVYDYYASGAEDQWTLKENRNAFARILFRPRILIDVSKIDMTTTV 250
+V+E AK LPKM YDYYASG+ DQ TL EN NAF+RI PR L+DVSK++ T +
Sbjct: 33 SVSELHEEAKRLLPKMAYDYYASGSNDQITLAENENAFSRIKLVPRSLVDVSKVNTKTRI 92
Query: 251 LGFKISMPIMVAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVAS-TGPGI 427
G IS PI++AP AMQ+MA GE T A+ TIMTLSS +T+SVE+++S T
Sbjct: 93 FGRDISTPILIAPWAMQRMASQRGELDTVEASKEFNTIMTLSSLSTTSVEDLSSATNGNP 152
Query: 428 RFFQLYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTLKNF 607
+FQLYV+K+RKV E+LV+RAE G+ A+ LTVDTP LG+R +D KN F LP L+LK F
Sbjct: 153 GWFQLYVFKDRKVSEELVKRAESIGYSALVLTVDTPFLGKRTADFKNSFKLPNGLSLKIF 212
Query: 608 EGLDLGKMDEANDSGLASYVAGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIAIQ 787
E L L + D GL Y+A ID +L+W D++WL++IT +PILVKG++ +DA +A+Q
Sbjct: 213 EKLMLSNL----DGGLNQYIATMIDPSLTWNDLKWLKSITKLPILVKGIMCPKDAELALQ 268
Query: 788 AGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALGAS 967
GA GIIVSNHG RQLD P+TI L + K +GRVP+ LDGG+RRGTDV KALA GA+
Sbjct: 269 YGADGIIVSNHGGRQLDTCPSTIEVLPYISKVVRGRVPLILDGGIRRGTDVLKALAFGAN 328
Query: 968 GIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHI 1120
+ IGRP+++ L+ G+ GV KVL +L E +L MAL+G ++S+I + I
Sbjct: 329 AVCIGRPIIWGLSTGGKDGVLKVLNLLNSELQLAMALTGITNISDINNSII 379
>sp|Q3ZBW2|HAOX2_BOVIN Hydroxyacid oxidase 2 OS=Bos taurus GN=HAO2 PE=2 SV=1
Length = 353
Score = 325 bits (832), Expect = 6e-088
Identities = 161/349 (46%), Positives = 240/349 (68%), Gaps = 8/349 (2%)
Frame = +2
Query: 77 TEYEAIAKEKLPKMVYDYYASGAEDQWTLKENRNAFARILFRPRILIDVSKIDMTTTVLG 256
T++ A+E L K +D+ GA+D T EN AF +I RPR L DVSK+DM TT+ G
Sbjct: 7 TDFREHAREHLSKSTWDFIEGGADDCCTRDENMAAFKKIRLRPRYLKDVSKVDMRTTIQG 66
Query: 257 FKISMPIMVAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGP-GIRF 433
+IS PI +APT ++A P+GE +TARAA AA S++A+ S+E++ + P G+R+
Sbjct: 67 AEISAPICIAPTGFHRLAWPDGEMSTARAAQAASICYITSTYASCSLEDIVAAAPRGLRW 126
Query: 434 FQLYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTLKNFEG 613
FQLYV+ NR++ +Q++++ E GFKA+ +TVD P++G R +DI N+ L L LK+
Sbjct: 127 FQLYVHPNRQINKQMIQKVESLGFKALVITVDVPKVGNRRNDITNQVDLMKKLLLKDLGS 186
Query: 614 LDLGKMDEANDSGLASYVAGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIAIQAG 793
++G + + + ID ++ W+D+ W Q++T +PI++KG+LT EDA +A++
Sbjct: 187 PEMGNV-------MPYFQMSPIDPSICWEDLSWFQSMTRLPIILKGILTKEDAELAVKHN 239
Query: 794 AAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALGASGI 973
GIIVSNHG RQLD VPA+I AL EVV A +G+V V+LDGG+R G DV KALALGA +
Sbjct: 240 VHGIIVSNHGGRQLDEVPASIDALTEVVAAVKGKVEVYLDGGIRTGNDVLKALALGAKCV 299
Query: 974 FIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHI 1120
F+GRP+++ LA +GE GV++VL +L++EF +M L+GCRS++EI ++ I
Sbjct: 300 FVGRPILWGLAYKGEHGVKEVLDILKNEFHTSMTLTGCRSVAEINQDLI 348
>sp|Q9NYQ3|HAOX2_HUMAN Hydroxyacid oxidase 2 OS=Homo sapiens GN=HAO2 PE=2 SV=1
Length = 351
Score = 309 bits (789), Expect = 6e-083
Identities = 163/345 (47%), Positives = 231/345 (66%), Gaps = 10/345 (2%)
Frame = +2
Query: 83 YEAIAKEKLPKMVYDYYASGAEDQWTLKENRNAFARILFRPRILIDVSKIDMTTTVLGFK 262
++A A+E+L K D+ GA+D T +N AF RI RPR L DVS++D TT+ G +
Sbjct: 9 FQAHAREQLSKSTRDFIEGGADDSITRDDNIAAFKRIRLRPRYLRDVSEVDTRTTIQGEE 68
Query: 263 ISMPIMVAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGP-GIRFFQ 439
IS PI +APT + P+GE +TARAA AAG S++A+ S+E++ P G+R+FQ
Sbjct: 69 ISAPICIAPTGFHCLVWPDGEMSTARAAQAAGICYITSTFASCSLEDIVIAAPEGLRWFQ 128
Query: 440 LYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTLKNFEGLD 619
LYV+ + ++ +QL++R E GFKA+ +T+DTP G R DI+N+ L NLTL + +
Sbjct: 129 LYVHPDLQLNKQLIQRVESLGFKALVITLDTPVCGNRRHDIRNQ--LRRNLTLTDLQSPK 186
Query: 620 LGKMDEANDSGLASYVAGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIAIQAGAA 799
G + + + I +L W D+ W Q+IT +PI++KG+LT EDA +A++
Sbjct: 187 KG-------NAIPYFQMTPISTSLCWNDLSWFQSITRLPIILKGILTKEDAELAVKHNVQ 239
Query: 800 GIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALGASGIFI 979
GIIVSNHG RQLD V A+I AL EVV A +G++ V+LDGGVR G DV KALALGA IF+
Sbjct: 240 GIIVSNHGGRQLDEVLASIDALTEVVAAVKGKIEVYLDGGVRTGNDVLKALALGAKCIFL 299
Query: 980 GRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRN 1114
GRP+++ LA +GE GV++VL +L +EF +MAL+GCRS++EI RN
Sbjct: 300 GRPILWGLACKGEHGVKEVLNILTNEFHTSMALTGCRSVAEINRN 344
>sp|Q07523|HAOX2_RAT Hydroxyacid oxidase 2 OS=Rattus norvegicus GN=Hao2 PE=1
SV=2
Length = 353
Score = 294 bits (750), Expect = 2e-078
Identities = 157/344 (45%), Positives = 227/344 (65%), Gaps = 8/344 (2%)
Frame = +2
Query: 80 EYEAIAKEKLPKMVYDYYASGAEDQWTLKENRNAFARILFRPRILIDVSKIDMTTTVLGF 259
+++A A+++L K +D+ A+D T EN AF RI RPR L D+SK+D TT+ G
Sbjct: 8 DFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRTTIQGQ 67
Query: 260 KISMPIMVAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGP-GIRFF 436
+IS PI ++PTA +A P+GE +TARAA A +SS+A+ S+E++ + P G R+F
Sbjct: 68 EISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPEGFRWF 127
Query: 437 QLYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTLKNFEGL 616
QLY+ + +Q+V+RAE GFKA+ +T+DTP LG R D +N+ L N+ LK+ L
Sbjct: 128 QLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLRAL 187
Query: 617 DLGKMDEANDSGLASYVAGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIAIQAGA 796
K ++ S S+ + W D+ LQ+IT +PI++KG+LT EDA +A++
Sbjct: 188 ---KEEKPTQSVPVSFPKA----SFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNV 240
Query: 797 AGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALGASGIF 976
GI+VSNHG RQLD V A+I AL EVV A +G++ V++DGGVR GTDV KALALGA IF
Sbjct: 241 QGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIF 300
Query: 977 IGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEIT 1108
+GRP+++ LA +GE GV++VL +L E M LSGC+S++EI+
Sbjct: 301 LGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEIS 344
>sp|Q9NYQ2|HAOX2_MOUSE Hydroxyacid oxidase 2 OS=Mus musculus GN=Hao2 PE=2 SV=1
Length = 353
Score = 287 bits (732), Expect = 2e-076
Identities = 156/344 (45%), Positives = 228/344 (66%), Gaps = 8/344 (2%)
Frame = +2
Query: 80 EYEAIAKEKLPKMVYDYYASGAEDQWTLKENRNAFARILFRPRILIDVSKIDMTTTVLGF 259
+++A A+++L K +D+ A+D T +N AF RI RPR L DVSKID TT+ G
Sbjct: 8 DFKAQAQKQLSKTSWDFIEGEADDGITYNDNLAAFRRIRLRPRYLRDVSKIDTRTTIQGQ 67
Query: 260 KISMPIMVAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGP-GIRFF 436
+I+ PI ++PTA +A +GE +TA+AA A +SS+A+ +VE++ + P G+ +F
Sbjct: 68 EINAPICISPTAFHSIAWADGEKSTAKAAQKANICYVISSYASYTVEDIVAAAPGGLHWF 127
Query: 437 QLYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTLKNFEGL 616
QLYV + + +Q+V+R E GFKA+ +TVD P LG R + ++ L N+ LK
Sbjct: 128 QLYVQPDWDINKQMVQRIEALGFKALVVTVDAPVLGNRRGNKRSLLDLEANIKLK----- 182
Query: 617 DLGKMDEANDSGLASYVAGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIAIQAGA 796
DL E+ SGL + ++ + W D+ LQ++T +PI++KG+LT EDA +A++
Sbjct: 183 DLRSPGESK-SGLPTPLS-MPSSSSCWNDLPLLQSMTRLPIILKGILTKEDAELAVKHNI 240
Query: 797 AGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALGASGIF 976
GIIVSNHG RQLD VPA+I AL EVV A G++ V++DGGVR G DV KALALGA IF
Sbjct: 241 RGIIVSNHGGRQLDEVPASIDALREVVAAVNGKIEVYMDGGVRTGNDVLKALALGARCIF 300
Query: 977 IGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEIT 1108
+GRP+++ LA +GE GV++VL +L++E MALSGCRS++EI+
Sbjct: 301 LGRPIIWGLACKGEDGVKEVLDILKEELHTCMALSGCRSVAEIS 344
>sp|Q1IF69|LLDD_PSEE4 L-lactate dehydrogenase [cytochrome] OS=Pseudomonas
entomophila (strain L48) GN=lldD PE=3 SV=1
Length = 381
Score = 150 bits (378), Expect = 3e-035
Identities = 72/176 (40%), Positives = 113/176 (64%), Gaps = 5/176 (2%)
Frame = +2
Query: 617 DLGKMDE--ANDSGLASYV---AGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIA 781
DLG + + N +GLA Y+ D ++SWKD++W++ P+++KG+L +DAR A
Sbjct: 203 DLGNISKYRGNPTGLADYIGWLGNNFDPSISWKDLEWIREFWDGPMIIKGILDADDARDA 262
Query: 782 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 961
++ GA GI+VSNHG RQLD V ++ AL + A +G + + D G+R G DV + +ALG
Sbjct: 263 VKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIKILADSGIRSGLDVVRMIALG 322
Query: 962 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIITE 1129
A + IGR +++LA GEAGV+ +L + E + M L+G +S+SEITR+ ++ E
Sbjct: 323 ADTVLIGRAFLYALATHGEAGVKNLLALFEKEMRVAMVLTGAKSISEITRDSLVRE 378
>sp|A5W9B2|LLDD_PSEP1 L-lactate dehydrogenase [cytochrome] OS=Pseudomonas putida
(strain F1 / ATCC 700007) GN=lldD PE=3 SV=1
Length = 381
Score = 149 bits (376), Expect = 4e-035
Identities = 71/176 (40%), Positives = 114/176 (64%), Gaps = 5/176 (2%)
Frame = +2
Query: 617 DLGKMDE--ANDSGLASYV---AGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIA 781
DLG + + N +GLA Y+ D ++SWKD++W++ P+++KG+L +DAR A
Sbjct: 203 DLGNISKYRGNPTGLADYIGWLGNNFDPSISWKDLEWIREFWDGPMIIKGILDADDARDA 262
Query: 782 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 961
++ GA GI+VSNHG RQLD V ++ AL + A +G + + D G+R G DV + +ALG
Sbjct: 263 VKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDLKILADSGIRSGLDVVRMIALG 322
Query: 962 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIITE 1129
A + IGR +++LA G+AGV+ +L++ E + M L+G +S+SEITR+ ++ E
Sbjct: 323 ADTVLIGRAFLYALAVHGQAGVKNLLELFEKEMRVAMVLTGAKSISEITRDSLVRE 378
>sp|Q88DT3|LLDD_PSEPK L-lactate dehydrogenase [cytochrome] OS=Pseudomonas putida
(strain KT2440) GN=lldD PE=3 SV=1
Length = 381
Score = 149 bits (376), Expect = 4e-035
Identities = 71/176 (40%), Positives = 114/176 (64%), Gaps = 5/176 (2%)
Frame = +2
Query: 617 DLGKMDE--ANDSGLASYV---AGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIA 781
DLG + + N +GLA Y+ D ++SWKD++W++ P+++KG+L +DAR A
Sbjct: 203 DLGNISKYRGNPTGLADYIGWLGNNFDPSISWKDLEWIREFWDGPMIIKGILDADDARDA 262
Query: 782 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 961
++ GA GI+VSNHG RQLD V ++ AL + A +G + + D G+R G DV + +ALG
Sbjct: 263 VKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDLKILADSGIRSGLDVVRMIALG 322
Query: 962 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIITE 1129
A + IGR +++LA G+AGV+ +L++ E + M L+G +S+SEITR+ ++ E
Sbjct: 323 ADTVLIGRAFLYALAVHGQAGVKNLLELFEKEMRVAMVLTGAKSISEITRDSLVRE 378
>sp|B0KIT4|LLDD_PSEPG L-lactate dehydrogenase [cytochrome] OS=Pseudomonas putida
(strain GB-1) GN=lldD PE=3 SV=1
Length = 381
Score = 149 bits (375), Expect = 6e-035
Identities = 71/176 (40%), Positives = 114/176 (64%), Gaps = 5/176 (2%)
Frame = +2
Query: 617 DLGKMDE--ANDSGLASYV---AGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIA 781
DLG + + N +GLA Y+ D ++SWKD++W++ P+++KG+L +DAR A
Sbjct: 203 DLGNISKYRGNPTGLADYIGWLGNNFDPSISWKDLEWIREYWDGPMIIKGILDADDARDA 262
Query: 782 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 961
++ GA GI+VSNHG RQLD V ++ AL + A +G + + D G+R G DV + +ALG
Sbjct: 263 VKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDLKILADSGIRSGLDVVRMIALG 322
Query: 962 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIITE 1129
A + IGR +++LA G+AGV+ +L++ E + M L+G +S+SEITR+ ++ E
Sbjct: 323 ADTVLIGRAFLYALAVHGQAGVKNLLELFEKEMRVAMVLTGAKSISEITRDSLVRE 378
>sp|B7V1I3|LLDD_PSEA8 L-lactate dehydrogenase [cytochrome] OS=Pseudomonas
aeruginosa (strain LESB58) GN=lldD PE=3 SV=1
Length = 381
Score = 148 bits (372), Expect = 1e-034
Identities = 71/176 (40%), Positives = 112/176 (63%), Gaps = 5/176 (2%)
Frame = +2
Query: 617 DLGKMD--EANDSGLASYV---AGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIA 781
DLG + N +GL Y+ D ++SWKD++W++ P+++KG+L EDAR A
Sbjct: 203 DLGNISAYRGNPTGLEDYIGWLGANFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDA 262
Query: 782 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 961
++ GA GI+VSNHG RQLD V ++ AL + A +G + + D G+R G DV + +ALG
Sbjct: 263 VKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELAILADSGIRTGLDVVRMIALG 322
Query: 962 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIITE 1129
A + +GR V++LAA GEAGVR +L+++ E + M L+G +S+ EI+ + ++ E
Sbjct: 323 ADSVLLGRAFVYALAAAGEAGVRNLLELIEKEMRVAMVLTGAKSIGEISADSLVRE 378
>sp|Q9HV37|LLDD_PSEAE L-lactate dehydrogenase [cytochrome] OS=Pseudomonas
aeruginosa GN=lldD PE=3 SV=1
Length = 381
Score = 148 bits (372), Expect = 1e-034
Identities = 71/176 (40%), Positives = 112/176 (63%), Gaps = 5/176 (2%)
Frame = +2
Query: 617 DLGKMD--EANDSGLASYV---AGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIA 781
DLG + N +GL Y+ D ++SWKD++W++ P+++KG+L EDAR A
Sbjct: 203 DLGNISAYRGNPTGLEDYIGWLGANFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDA 262
Query: 782 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 961
++ GA GI+VSNHG RQLD V ++ AL + A +G + + D G+R G DV + +ALG
Sbjct: 263 VKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELAILADSGIRTGLDVVRMIALG 322
Query: 962 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIITE 1129
A + +GR V++LAA GEAGVR +L+++ E + M L+G +S+ EI+ + ++ E
Sbjct: 323 ADSVLLGRAFVYALAAAGEAGVRNLLELIEKEMRVAMVLTGAKSIGEISADSLVRE 378
>sp|A6VCM8|LLDD_PSEA7 L-lactate dehydrogenase [cytochrome] OS=Pseudomonas
aeruginosa (strain PA7) GN=lldD PE=3 SV=1
Length = 381
Score = 147 bits (370), Expect = 2e-034
Identities = 70/176 (39%), Positives = 113/176 (64%), Gaps = 5/176 (2%)
Frame = +2
Query: 617 DLGKMD--EANDSGLASYV---AGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIA 781
DLG + N +GL Y+ D ++SWKD++W++ + P+++KG+L EDA+ A
Sbjct: 203 DLGNISTYRGNPTGLEDYIGWLGANFDPSISWKDLEWIREFWNGPMVIKGILDPEDAKDA 262
Query: 782 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 961
++ GA GI+VSNHG RQLD V ++ AL + A +G + + D G+R G DV + +ALG
Sbjct: 263 VKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELAILADSGIRTGLDVVRMIALG 322
Query: 962 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIITE 1129
A + +GR V++LAA GEAGVR +L+++ E + M L+G +S+ EI+ + ++ E
Sbjct: 323 ADSVLLGRAFVYALAAAGEAGVRNLLELIEKEMRVAMVLTGAKSIGEISADSLVRE 378
>sp|Q02FQ1|LLDD_PSEAB L-lactate dehydrogenase [cytochrome] OS=Pseudomonas
aeruginosa (strain UCBPP-PA14) GN=lldD PE=3 SV=1
Length = 381
Score = 147 bits (369), Expect = 3e-034
Identities = 70/176 (39%), Positives = 112/176 (63%), Gaps = 5/176 (2%)
Frame = +2
Query: 617 DLGKMD--EANDSGLASYV---AGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIA 781
DLG + N +GL Y+ D +++WKD++W++ P+++KG+L EDAR A
Sbjct: 203 DLGNISAYRGNPTGLEDYIGWLGANFDPSIAWKDLEWIREFWDGPMVIKGILDPEDARDA 262
Query: 782 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 961
++ GA GI+VSNHG RQLD V ++ AL + A +G + + D G+R G DV + +ALG
Sbjct: 263 VKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELAILADSGIRTGLDVVRMIALG 322
Query: 962 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIITE 1129
A + +GR V++LAA GEAGVR +L+++ E + M L+G +S+ EI+ + ++ E
Sbjct: 323 ADSVLLGRAFVYALAAAGEAGVRNLLELIEKEMRVAMVLTGAKSIGEISADSLVRE 378
>sp|B2FIJ0|LLDD_STRMK L-lactate dehydrogenase [cytochrome] OS=Stenotrophomonas
maltophilia (strain K279a) GN=lldD PE=3 SV=1
Length = 379
Score = 145 bits (365), Expect = 8e-034
Identities = 71/175 (40%), Positives = 111/175 (63%), Gaps = 5/175 (2%)
Frame = +2
Query: 617 DLGKMD--EANDSGLASYV---AGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIA 781
DLG + N +GL Y+ D ++SWKD++W++ P+++KG+L +DAR A
Sbjct: 203 DLGNISTYRGNPTGLEDYIGWLGSNFDPSISWKDLEWIREFWKGPMVIKGILDPDDARDA 262
Query: 782 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 961
++ GA GI+VSNHG RQLD V +T AL + A QG + + D G+R G DV + LALG
Sbjct: 263 VRFGADGIVVSNHGGRQLDGVLSTARALPAIADAVQGDLKILADSGIRTGLDVVRMLALG 322
Query: 962 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIIT 1126
A + +GR V++LAA+GEAGV +L ++ E + M L+G R +++I R+ +++
Sbjct: 323 ADTVLLGRAFVYALAAQGEAGVANLLDLIAKEMRVAMTLTGARRIADIGRDSLVS 377
>sp|A8ARJ1|LLDD_CITK8 L-lactate dehydrogenase [cytochrome] OS=Citrobacter koseri
(strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) GN=lldD PE=3 SV=1
Length = 396
Score = 144 bits (363), Expect = 1e-033
Identities = 69/176 (39%), Positives = 112/176 (63%), Gaps = 5/176 (2%)
Frame = +2
Query: 617 DLGKMDE--ANDSGLASYV---AGQIDRTLSWKDVQWLQTITSMPILVKGVLTGEDARIA 781
DLG + +GL Y+ A D ++SWKD++W++ P+++KG+L EDAR A
Sbjct: 203 DLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDA 262
Query: 782 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 961
++ GA GI+VSNHG RQLD V ++ AL + A +G + + D G+R G DV + +ALG
Sbjct: 263 VRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALG 322
Query: 962 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLSEITRNHIITE 1129
A + +GR +++LA G+AGV +L ++ E ++ M L+G +S+SEI+R+ ++ E
Sbjct: 323 ADSVLLGRAYLYALATAGQAGVANLLDLIEKEMKVAMTLTGAKSISEISRDSLVQE 378
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,796,540,212
Number of Sequences: 518415
Number of Extensions: 51796540212
Number of Successful Extensions: 358348623
Number of sequences better than 0.0: 0
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