BLASTX 7.6.2
Query= UN13369 /QuerySize=1110
(1109 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P31251|UBE12_WHEAT Ubiquitin-activating enzyme E1 2 OS=Tritic... 489 2e-137
sp|P20973|UBE11_WHEAT Ubiquitin-activating enzyme E1 1 OS=Tritic... 486 1e-136
sp|P31252|UBE13_WHEAT Ubiquitin-activating enzyme E1 3 OS=Tritic... 452 3e-126
sp|A3KMV5|UBA1_BOVIN Ubiquitin-like modifier-activating enzyme 1... 203 2e-051
sp|Q29504|UBA1_RABIT Ubiquitin-like modifier-activating enzyme 1... 202 5e-051
sp|P22314|UBA1_HUMAN Ubiquitin-like modifier-activating enzyme 1... 201 7e-051
sp|P22515|UBA1_YEAST Ubiquitin-activating enzyme E1 1 OS=Sacchar... 201 1e-050
sp|P31254|UBA1Y_MOUSE Ubiquitin-like modifier-activating enzyme ... 196 2e-049
sp|Q02053|UBA1_MOUSE Ubiquitin-like modifier-activating enzyme 1... 196 4e-049
sp|Q5U300|UBA1_RAT Ubiquitin-like modifier-activating enzyme 1 O... 196 4e-049
sp|O94609|UBA1_SCHPO Ubiquitin-activating enzyme E1 1 OS=Schizos... 186 4e-046
sp|Q55C16|UBA1_DICDI Ubiquitin-like modifier-activating enzyme 1... 178 6e-044
sp|P52495|UBA1_CANAL Ubiquitin-activating enzyme E1 1 (Fragment)... 176 3e-043
sp|Q8C7R4|UBA6_MOUSE Ubiquitin-like modifier-activating enzyme 6... 142 7e-033
sp|A0AVT1|UBA6_HUMAN Ubiquitin-like modifier-activating enzyme 6... 141 1e-032
sp|P41226|UBA7_HUMAN Ubiquitin-like modifier-activating enzyme 7... 133 3e-030
sp|Q54L40|SAE2_DICDI SUMO-activating enzyme subunit 2 OS=Dictyos... 56 5e-007
sp|Q9NAN1|SAE2_CAEEL SUMO-activating enzyme subunit uba-2 OS=Cae... 54 1e-006
sp|Q28GH3|SAE2_XENTR SUMO-activating enzyme subunit 2 OS=Xenopus... 54 1e-006
sp|Q9UBT2|SAE2_HUMAN SUMO-activating enzyme subunit 2 OS=Homo sa... 54 2e-006
>sp|P31251|UBE12_WHEAT Ubiquitin-activating enzyme E1 2 OS=Triticum aestivum
GN=UBA2 PE=2 SV=1
Length = 1051
Score = 489 bits (1257), Expect = 2e-137
Identities = 234/306 (76%), Positives = 271/306 (88%), Gaps = 1/306 (0%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNP-KEAAEAVDSVIVPDFEPREDAK 930
P+++SSSDPS L+FI A AILRAETFGIP+ +W K P K AAEAVD VIVPDF+P++ K
Sbjct: 746 PVEFSSSDPSQLSFILAAAILRAETFGIPISEWAKTPNKLAAEAVDKVIVPDFQPKQGVK 805
Query: 929 IVTDEKATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDVIS 750
IVTDEKATSL++ASVDDA VI +LIAKLE L F M P+QFEKDDDTN+HMDVI+
Sbjct: 806 IVTDEKATSLSSASVDDAAVIEELIAKLEEVSKTLPSGFHMNPIQFEKDDDTNFHMDVIA 865
Query: 749 GLANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYR 570
G ANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYK L GGHKVE YR
Sbjct: 866 GFANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKALAGGHKVEDYR 925
Query: 569 NTFANLALPLFSMAEPVPPKVVKHRDMAWTVWDRWVLKGNPTLREVLQWLEDKGLNAYSI 390
NTFANLA+PLFS+AEPVPPK +KH++++WTVWDRW + GN TLRE+L+WL++KGLNAYSI
Sbjct: 926 NTFANLAIPLFSIAEPVPPKTIKHQELSWTVWDRWTVTGNITLRELLEWLKEKGLNAYSI 985
Query: 389 SCGSCLLFNSMFPRHKERMDKKVVDLARDIAKVELPPYRHHLDVVVACEDQDDNDVDIPL 210
SCG+ LL+NSMFPRHKER+D+KVVD+AR++AK+E+P YR HLDVVVACED DDNDVDIPL
Sbjct: 986 SCGTSLLYNSMFPRHKERLDRKVVDVAREVAKMEVPSYRRHLDVVVACEDDDDNDVDIPL 1045
Query: 209 VSIYFR 192
VS+YFR
Sbjct: 1046 VSVYFR 1051
>sp|P20973|UBE11_WHEAT Ubiquitin-activating enzyme E1 1 OS=Triticum aestivum
GN=UBA1 PE=1 SV=1
Length = 1051
Score = 486 bits (1250), Expect = 1e-136
Identities = 233/306 (76%), Positives = 270/306 (88%), Gaps = 1/306 (0%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNP-KEAAEAVDSVIVPDFEPREDAK 930
P+++SSSD S L+FI A AILRAETFGIP+P+W K P K AAEAVD VIVPDF+P++ K
Sbjct: 746 PVEFSSSDQSQLSFILAAAILRAETFGIPIPEWAKTPNKLAAEAVDKVIVPDFQPKQGVK 805
Query: 929 IVTDEKATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDVIS 750
IVT EKATSL++ASVDDA VI +LIAKLE L F M P+QFEKDDDTN+HMDVI+
Sbjct: 806 IVTHEKATSLSSASVDDAAVIEELIAKLEEVSKTLPSGFHMNPIQFEKDDDTNFHMDVIA 865
Query: 749 GLANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYR 570
G ANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYK L GGHKVE YR
Sbjct: 866 GFANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKALAGGHKVEDYR 925
Query: 569 NTFANLALPLFSMAEPVPPKVVKHRDMAWTVWDRWVLKGNPTLREVLQWLEDKGLNAYSI 390
NTFANLA+PLFS+AEPVPPK +KH++++WTVWDRW + GN TLRE+L+WL++KGLNAYSI
Sbjct: 926 NTFANLAIPLFSIAEPVPPKTIKHQELSWTVWDRWTVTGNITLRELLEWLKEKGLNAYSI 985
Query: 389 SCGSCLLFNSMFPRHKERMDKKVVDLARDIAKVELPPYRHHLDVVVACEDQDDNDVDIPL 210
SCG+ LL+NSMFPRHKER+D+KVVD+AR++AK+E+P YR HLDVVVACED DDNDVDIPL
Sbjct: 986 SCGTSLLYNSMFPRHKERLDRKVVDVAREVAKMEVPSYRRHLDVVVACEDDDDNDVDIPL 1045
Query: 209 VSIYFR 192
VS+YFR
Sbjct: 1046 VSVYFR 1051
>sp|P31252|UBE13_WHEAT Ubiquitin-activating enzyme E1 3 OS=Triticum aestivum
GN=UBA3 PE=2 SV=1
Length = 1053
Score = 452 bits (1161), Expect = 3e-126
Identities = 212/304 (69%), Positives = 260/304 (85%)
Frame = -1
Query: 1103 LQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNPKEAAEAVDSVIVPDFEPREDAKIV 924
LQ+S++D S LNFI + +ILRAE+FG+ +P+W K+ + A+ V+ + VP FEP++ IV
Sbjct: 750 LQFSAADQSHLNFIMSASILRAESFGVAIPEWAKDTSKLADVVNKIAVPTFEPKQGVNIV 809
Query: 923 TDEKATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDVISGL 744
TDEKA++L++ SVDD VI DL+AKL+ L P F+MKP+QFEKDDDTN+HMD+ISGL
Sbjct: 810 TDEKASNLSSTSVDDVAVIEDLLAKLQEYAKMLLPGFQMKPIQFEKDDDTNFHMDLISGL 869
Query: 743 ANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYRNT 564
ANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKV+ G H VE YRNT
Sbjct: 870 ANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVIAGEHPVEDYRNT 929
Query: 563 FANLALPLFSMAEPVPPKVVKHRDMAWTVWDRWVLKGNPTLREVLQWLEDKGLNAYSISC 384
FANLALPLFSMAEPVPPKV+KH++ +WTVWDRW ++GN TL E+LQW DKGL AYSISC
Sbjct: 930 FANLALPLFSMAEPVPPKVMKHKETSWTVWDRWSVQGNLTLAELLQWFADKGLTAYSISC 989
Query: 383 GSCLLFNSMFPRHKERMDKKVVDLARDIAKVELPPYRHHLDVVVACEDQDDNDVDIPLVS 204
G+ LL+N+MF RHK+R+ KKVVD+AR++AKV++P YR HLD+ VACED+D+NDVDIPLVS
Sbjct: 990 GTSLLYNNMFARHKDRLTKKVVDIAREVAKVDVPEYRRHLDIGVACEDEDENDVDIPLVS 1049
Query: 203 IYFR 192
+YFR
Sbjct: 1050 VYFR 1053
>sp|A3KMV5|UBA1_BOVIN Ubiquitin-like modifier-activating enzyme 1 OS=Bos taurus
GN=UBA1 PE=2 SV=1
Length = 1058
Score = 203 bits (515), Expect = 2e-051
Identities = 116/314 (36%), Positives = 182/314 (57%), Gaps = 15/314 (4%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNPKEAAEAVDSVIVPDFEPREDAKI 927
PL + S+P L+++ A A L A+T+G+ +++ A + SV VP+F P+ KI
Sbjct: 751 PLTFDVSNPLHLDYVIAAANLFAQTYGL---TGSQDRAAVATLLQSVQVPEFTPKSGVKI 807
Query: 926 VTDEKATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDVISG 747
++ ASVDD+ + +L A L P F+M P+ FEKDDDTN+HMD I
Sbjct: 808 HVSDQELQSANASVDDSR-LEELKATLP--SPEKLPGFKMYPIDFEKDDDTNFHMDFIVA 864
Query: 746 LANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYRN 567
+N+RA NY IP D+ K+K IAG+IIPAIAT+TA GLVCLELYKV+ G ++ +Y+N
Sbjct: 865 ASNLRAENYDIPPADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRQLNSYKN 924
Query: 566 TFANLALPLFSMAEPVPPKVVKHRDMAWTVWDRWVLKG------NPTLREVLQWLE-DKG 408
F NLALP F +EP+ ++ + WT+WDR+ ++G TL++ L + + +
Sbjct: 925 GFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHK 984
Query: 407 LNAYSISCGSCLLFNSMFP--RHKERMDKKVVDLARDIAKVELPPYRHHLDVVVACEDQD 234
L +S G +L++ P + KER+D+ + ++ ++K +L + L + + C D+
Sbjct: 985 LEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDES 1044
Query: 233 DNDVDIPLVSIYFR 192
DV++P V R
Sbjct: 1045 GEDVEVPYVRYTIR 1058
>sp|Q29504|UBA1_RABIT Ubiquitin-like modifier-activating enzyme 1 OS=Oryctolagus
cuniculus GN=UBA1 PE=2 SV=1
Length = 1058
Score = 202 bits (512), Expect = 5e-051
Identities = 115/314 (36%), Positives = 183/314 (58%), Gaps = 15/314 (4%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNPKEAAEAVDSVIVPDFEPREDAKI 927
PL + S+P L+++ A A L A+T+G+ +++ A + SV VP+F P+ KI
Sbjct: 751 PLTFDVSNPLHLDYVMAAANLFAQTYGLA---GSQDRAAVATLLQSVQVPEFTPKSGVKI 807
Query: 926 VTDEKATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDVISG 747
++ ASVDD+ + +L A L + P F+M P+ FEKDDD+N+HMD I
Sbjct: 808 HVSDQELQSANASVDDSR-LEELKATLP--SPDKLPGFKMYPIDFEKDDDSNFHMDFIVA 864
Query: 746 LANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYRN 567
+N+RA NY IP D+ K+K IAG+IIPAIAT+TA GLVCLELYKV+ G +++Y+N
Sbjct: 865 ASNLRAENYDIPPADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRHLDSYKN 924
Query: 566 TFANLALPLFSMAEPVPPKVVKHRDMAWTVWDRWVLKG------NPTLREVLQWLE-DKG 408
F NLALP F +EP+ ++ + WT+WDR+ ++G TL++ L + + +
Sbjct: 925 GFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHK 984
Query: 407 LNAYSISCGSCLLFNSMFP--RHKERMDKKVVDLARDIAKVELPPYRHHLDVVVACEDQD 234
L +S G +L++ P + KER+D+ + ++ ++K +L + L + + C D+
Sbjct: 985 LEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDES 1044
Query: 233 DNDVDIPLVSIYFR 192
DV++P V R
Sbjct: 1045 GEDVEVPYVRYTIR 1058
>sp|P22314|UBA1_HUMAN Ubiquitin-like modifier-activating enzyme 1 OS=Homo
sapiens GN=UBA1 PE=1 SV=3
Length = 1058
Score = 201 bits (511), Expect = 7e-051
Identities = 114/314 (36%), Positives = 184/314 (58%), Gaps = 15/314 (4%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNPKEAAEAVDSVIVPDFEPREDAKI 927
PL + ++P L+++ A A L A+T+G+ +++ A + SV VP+F P+ KI
Sbjct: 751 PLTFDVNNPLHLDYVMAAANLFAQTYGL---TGSQDRAAVATFLQSVQVPEFTPKSGVKI 807
Query: 926 VTDEKATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDVISG 747
++ ASVDD+ + +L A L + P F+M P+ FEKDDD+N+HMD I
Sbjct: 808 HVSDQELQSANASVDDSR-LEELKATLP--SPDKLPGFKMYPIDFEKDDDSNFHMDFIVA 864
Query: 746 LANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYRN 567
+N+RA NY IP D+ K+K IAG+IIPAIAT+TA GLVCLELYKV+ G ++++Y+N
Sbjct: 865 ASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRQLDSYKN 924
Query: 566 TFANLALPLFSMAEPVPPKVVKHRDMAWTVWDRWVLKG------NPTLREVLQWLE-DKG 408
F NLALP F +EP+ ++ + WT+WDR+ ++G TL++ L + + +
Sbjct: 925 GFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHK 984
Query: 407 LNAYSISCGSCLLFNSMFP--RHKERMDKKVVDLARDIAKVELPPYRHHLDVVVACEDQD 234
L +S G +L++ P + KER+D+ + ++ ++K +L + L + + C D+
Sbjct: 985 LEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDES 1044
Query: 233 DNDVDIPLVSIYFR 192
DV++P V R
Sbjct: 1045 GEDVEVPYVRYTIR 1058
>sp|P22515|UBA1_YEAST Ubiquitin-activating enzyme E1 1 OS=Saccharomyces
cerevisiae GN=UBA1 PE=1 SV=2
Length = 1024
Score = 201 bits (509), Expect = 1e-050
Identities = 110/309 (35%), Positives = 181/309 (58%), Gaps = 8/309 (2%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNPK--EAAEAVDSVIVPDFEPREDA 933
PL++ + +F+ A A LRA +GI D P E +D +I+P+F P +
Sbjct: 717 PLEFDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANL 776
Query: 932 KIVTDEKATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDVI 753
KI ++ + + + I+ L++ L + F+++PV FEKDDDTN+H++ I
Sbjct: 777 KIQVNDDDPDPNANAANGSDEIDQLVSSLP--DPSTLAGFKLEPVDFEKDDDTNHHIEFI 834
Query: 752 SGLANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAY 573
+ +N RA+NY I D+ K KFIAGRIIPAIAT+T++ TGLV LELYK++D +E Y
Sbjct: 835 TACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQY 894
Query: 572 RNTFANLALPLFSMAEPV-PPKVVKHRDMAWTVWDRWVLKGNPTLREVLQWLE-DKGLNA 399
+N F NLALP F +EP+ PK + +WDR+ +KG+ L ++++ E D+GL
Sbjct: 895 KNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEI 954
Query: 398 YSISCGSCLLFNSMFP--RHKERMDKKVVDLARDIAKVELPPYRHHLDVVVACEDQDDND 225
+S G LL+ S FP + KER++ + L + + K ++P + + + + +D++ D
Sbjct: 955 TMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGED 1014
Query: 224 VDIPLVSIY 198
V++P ++I+
Sbjct: 1015 VEVPFITIH 1023
>sp|P31254|UBA1Y_MOUSE Ubiquitin-like modifier-activating enzyme 1 Y OS=Mus
musculus GN=Ube1ay PE=2 SV=2
Length = 1058
Score = 196 bits (498), Expect = 2e-049
Identities = 111/318 (34%), Positives = 185/318 (58%), Gaps = 22/318 (6%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNPKEAAEAVDSVIVPDFEPREDAKI 927
PL + ++P L+++ A A L A+T+G+ +++ A+ + S+ VP F P+ +I
Sbjct: 750 PLTFDINNPLHLDYVMAAANLFAQTYGL---GGSQDCAVVAKLLQSLPVPKFAPKSGIRI 806
Query: 926 VTDEKATSLTTASVDDATVINDLIAKLERCRHNLSPD----FRMKPVQFEKDDDTNYHMD 759
E+ T+A+ D + + +L L +PD F+M P+ FEKDDD+N+HMD
Sbjct: 807 HVSEQELQSTSATTIDDSHLEELKTALP------TPDKLLGFKMYPIDFEKDDDSNFHMD 860
Query: 758 VISGLANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVE 579
I +N+RA NY I D+ K+K IAG+IIPAIAT+T+ GLVCLELYKV+ G ++E
Sbjct: 861 FIVAASNLRAENYGISPADRHKSKLIAGKIIPAIATTTSAIVGLVCLELYKVVQGHQQLE 920
Query: 578 AYRNTFANLALPLFSMAEPVPPKVVKHRDMAWTVWDRWVLKG------NPTLREVLQWLE 417
+Y+N+F NLALPLFS + P+ P+ ++ D WT+WDR+ ++G TL++ L + +
Sbjct: 921 SYKNSFINLALPLFSFSAPLAPECHQYYDQEWTLWDRFDVQGLQPSGEEMTLKQFLDYFK 980
Query: 416 -DKGLNAYSISCGSCLLFNSMFP--RHKERMDKKVVDLARDIAKVELPPYRHHLDVVVAC 246
+ L +S G +L++ P + KER+D+ + ++ ++K +L + L + C
Sbjct: 981 TEHKLEVIMLSQGVSMLYSVFMPASKLKERLDQPMTEIVSCVSKQKLGHHVKSLVFELCC 1040
Query: 245 EDQDDNDVDIPLVSIYFR 192
+D+++P V R
Sbjct: 1041 NSDSGDDIEVPYVRYIIR 1058
>sp|Q02053|UBA1_MOUSE Ubiquitin-like modifier-activating enzyme 1 OS=Mus
musculus GN=Uba1 PE=1 SV=1
Length = 1058
Score = 196 bits (496), Expect = 4e-049
Identities = 112/314 (35%), Positives = 182/314 (57%), Gaps = 15/314 (4%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNPKEAAEAVDSVIVPDFEPREDAKI 927
PL + ++ L+++ A A L A+T+G+ +++ A + SV VP+F P+ KI
Sbjct: 751 PLTFDVNNTLHLDYVMAAANLFAQTYGL---TGSQDRAAVASLLQSVQVPEFTPKSGVKI 807
Query: 926 VTDEKATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDVISG 747
++ ASVDD+ + +L A L + P F+M P+ FEKDDD+N+HMD I
Sbjct: 808 HVSDQELQSANASVDDSR-LEELKATLP--SPDKLPGFKMYPIDFEKDDDSNFHMDFIVA 864
Query: 746 LANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYRN 567
+N+RA NY I D+ K+K IAG+IIPAIAT+TA GLVCLELYKV+ G ++++Y+N
Sbjct: 865 ASNLRAENYDISPADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHQQLDSYKN 924
Query: 566 TFANLALPLFSMAEPVPPKVVKHRDMAWTVWDRWVLKG------NPTLREVLQWLE-DKG 408
F NLALP F +EP+ ++ + WT+WDR+ ++G TL++ L + + +
Sbjct: 925 GFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHK 984
Query: 407 LNAYSISCGSCLLFNSMFP--RHKERMDKKVVDLARDIAKVELPPYRHHLDVVVACEDQD 234
L +S G +L++ P + KER+D+ + ++ ++K +L + L + + C D+
Sbjct: 985 LEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDES 1044
Query: 233 DNDVDIPLVSIYFR 192
DV++P V R
Sbjct: 1045 GEDVEVPYVRYTIR 1058
>sp|Q5U300|UBA1_RAT Ubiquitin-like modifier-activating enzyme 1 OS=Rattus
norvegicus GN=Uba1 PE=1 SV=1
Length = 1058
Score = 196 bits (496), Expect = 4e-049
Identities = 112/314 (35%), Positives = 182/314 (57%), Gaps = 15/314 (4%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNPKEAAEAVDSVIVPDFEPREDAKI 927
PL + ++ L+++ A A L A+T+G+ +++ A + SV VP+F P+ KI
Sbjct: 751 PLTFDVNNTLHLDYVMAAANLFAQTYGL---TGSQDRAAVASLLQSVQVPEFTPKSGVKI 807
Query: 926 VTDEKATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDVISG 747
++ ASVDD+ + +L A L + P F+M P+ FEKDDD+N+HMD I
Sbjct: 808 HVSDQELQSANASVDDSR-LEELKATLP--SPDKLPGFKMYPIDFEKDDDSNFHMDFIVA 864
Query: 746 LANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYRN 567
+N+RA NY I D+ K+K IAG+IIPAIAT+TA GLVCLELYKV+ G ++++Y+N
Sbjct: 865 ASNLRAENYDISPADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHQQLDSYKN 924
Query: 566 TFANLALPLFSMAEPVPPKVVKHRDMAWTVWDRWVLKG------NPTLREVLQWLE-DKG 408
F NLALP F +EP+ ++ + WT+WDR+ ++G TL++ L + + +
Sbjct: 925 GFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHK 984
Query: 407 LNAYSISCGSCLLFNSMFP--RHKERMDKKVVDLARDIAKVELPPYRHHLDVVVACEDQD 234
L +S G +L++ P + KER+D+ + ++ ++K +L + L + + C D+
Sbjct: 985 LEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDES 1044
Query: 233 DNDVDIPLVSIYFR 192
DV++P V R
Sbjct: 1045 GEDVEVPYVRYTIR 1058
>sp|O94609|UBA1_SCHPO Ubiquitin-activating enzyme E1 1 OS=Schizosaccharomyces
pombe GN=ptr3 PE=1 SV=1
Length = 1012
Score = 186 bits (470), Expect = 4e-046
Identities = 107/306 (34%), Positives = 172/306 (56%), Gaps = 10/306 (3%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNPKEAAEAVDSVIVPDFEPREDAKI 927
PL + + +FI A A L A +G+ +P + P F P+ KI
Sbjct: 711 PLSFDIHNREHFDFIVAAASLYAFNYGLKS---ETDPAIYERVLAGYNPPPFAPKSGIKI 767
Query: 926 VTDEKATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDVISG 747
+E + TA+ D + + L + FR+ P +FEKDDD+N+H+D I+
Sbjct: 768 QVNENEEAPETAANKDKQELKSIADSLPPPSSLVG--FRLTPAEFEKDDDSNHHIDFITA 825
Query: 746 LANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYRN 567
+N+RA NY I D+ K KF+AG+I+PA+ TSTA+ +GLVCLEL K++DG K+E Y+N
Sbjct: 826 ASNLRAMNYDITPADRFKTKFVAGKIVPAMCTSTAVVSGLVCLELVKLVDGKKKIEEYKN 885
Query: 566 TFANLALPLFSMAEPV-PPKVVKHRDMAWTVWDRWVLKGNPTLREVLQWLE-DKGLNAYS 393
F NLA+ LF+ ++P+ PK+ + +WDR+ L + TL+E++ + + ++GL
Sbjct: 886 GFFNLAIGLFTFSDPIASPKMKVNGKEIDKIWDRYNLP-DCTLQELIDYFQKEEGLEVTM 944
Query: 392 ISCGSCLLFNSMFPRHK--ERMDKKVVDLARDIAKVELPPYRHHLDVVVACEDQDDNDVD 219
+S G LL+ + P K ER+ K+ +L I K +L P+R HL + + C+D + DV+
Sbjct: 945 LSSGVSLLYANFQPPKKLAERLPLKISELVEQITKKKLEPFRKHLVLEICCDDANGEDVE 1004
Query: 218 IPLVSI 201
+P + I
Sbjct: 1005 VPFICI 1010
>sp|Q55C16|UBA1_DICDI Ubiquitin-like modifier-activating enzyme 1
OS=Dictyostelium discoideum GN=uba1 PE=3 SV=1
Length = 1017
Score = 178 bits (451), Expect = 6e-044
Identities = 118/315 (37%), Positives = 174/315 (55%), Gaps = 27/315 (8%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNPKEAAEAVDSVIVPDFEPREDAKI 927
PL++ +P L FI A A LRA +GI N + + +VIVPDF P++ KI
Sbjct: 710 PLKFDVENPLHLEFIVAAANLRAFNYGIKA---ETNIEVIQKQAANVIVPDFTPKK-VKI 765
Query: 926 VTDEK---ATSLTTASVDDA------TVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDT 774
T E +S T + DA T+++ L E +++ +QFEKDDDT
Sbjct: 766 QTSENEPAPSSNTQQAGGDAEDDQCDTILSQLPQPSEMA------GYKINSIQFEKDDDT 819
Query: 773 NYHMDVISGLANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDG 594
N+H+D I+ +N+RA NY+I DK K K IAG+IIPA+ T+TA+ G VC+EL KV+
Sbjct: 820 NHHIDFITATSNLRATNYAISPADKHKTKGIAGKIIPALVTTTAVVAGFVCIELIKVIQ- 878
Query: 593 GHKVEAYRNTFANLALPLFSMAEPV-PPKVVKHRDMAWTVWDRWVLKGNPTLREVLQWLE 417
+E Y++TF NL +P F EP+ PK WT+WDR+ + G+ TL+E L E
Sbjct: 879 NKALEKYKSTFMNLGIPFFGFVEPIAAPKNKIREGWTWTLWDRFDVDGDITLKEFLDLFE 938
Query: 416 DK-GLNAYSISCGSCLLFNSMFPRHK---ERMDKKVVDLARDIAKVELPPYRHHLDVVVA 249
K GL+ +SC LL+ ++F K ER+ K+ L ++K LP + +L + +
Sbjct: 939 KKHGLDISMLSCKVTLLY-ALFTDKKTKEERLKMKISQLYETLSKKPLPKDKKYLLLEIC 997
Query: 248 CED-QDDNDVDIPLV 207
C D + +DVD+P V
Sbjct: 998 CNDTETGDDVDVPSV 1012
>sp|P52495|UBA1_CANAL Ubiquitin-activating enzyme E1 1 (Fragment) OS=Candida
albicans GN=UBA1 PE=3 SV=1
Length = 205
Score = 176 bits (445), Expect = 3e-043
Identities = 89/203 (43%), Positives = 134/203 (66%), Gaps = 4/203 (1%)
Frame = -1
Query: 797 QFEKDDDTNYHMDVISGLANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCL 618
+FEKDDDTN+H++ I+ +N RA NY I D K KFIAG+IIPAIAT+TA+ TGLVCL
Sbjct: 1 EFEKDDDTNHHIEFITAASNCRALNYGIEIADAHKTKFIAGKIIPAIATTTALVTGLVCL 60
Query: 617 ELYKVLDGGHKVEAYRNTFANLALPLFSMAEPVPPKVVKHRDMAW-TVWDRWVLKGNPTL 441
ELYKV+DG +E Y+N F NLALP +EP+ K+ + + +WDR+ L G+ TL
Sbjct: 61 ELYKVVDGKDDIEQYKNGFINLALPFIGFSEPIKSPEGKYNNKKFDQIWDRFELNGDITL 120
Query: 440 REVLQWLE-DKGLNAYSISCGSCLLFNSMFP--RHKERMDKKVVDLARDIAKVELPPYRH 270
+E+L E ++GL +S G LL+ S FP + K+R+ K+ L ++++K E+P +
Sbjct: 121 QELLDHFEKEEGLTISMLSYGVSLLYASFFPPKKVKDRLGLKLTSLIKEVSKKEVPSHVK 180
Query: 269 HLDVVVACEDQDDNDVDIPLVSI 201
+L + C+D++ DV++P + +
Sbjct: 181 NLIFEICCDDEEGEDVEVPYICV 203
>sp|Q8C7R4|UBA6_MOUSE Ubiquitin-like modifier-activating enzyme 6 OS=Mus
musculus GN=Uba6 PE=1 SV=1
Length = 1053
Score = 142 bits (356), Expect = 7e-033
Identities = 89/265 (33%), Positives = 147/265 (55%), Gaps = 10/265 (3%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNPKEAAEAVDSVIVPDFEPREDAKI 927
P+++ ++P L+F+ + A L A + IP + + + + V + +F+P + +
Sbjct: 744 PIKFDLNEPLHLSFLQSAAKLYATVYCIPFSEKDLSVNSLMDILSEVKIEEFKP-SNKVV 802
Query: 926 VTDE---KATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDV 756
TDE K + +S D+ + L L + S D +M + FEKDDD N H+D
Sbjct: 803 QTDETARKPDHVPVSSEDERNAVFQLEEALSSNKATKS-DLQMTVLSFEKDDDRNGHIDF 861
Query: 755 ISGLANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEA 576
I+ +N+RA+ YSI D+ K K IAG+IIPAIATSTA +GLV LE+ KV GG+ +A
Sbjct: 862 ITAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATSTAAVSGLVALEMIKVA-GGYPFDA 920
Query: 575 YRNTFANLALPLFSMAEPVPPKVVKHRD-MAWTVWDRWVLKGNP--TLREVLQWL-EDKG 408
Y+N F NLA+P+ E + + R+ +++T+WDRW + G TL + + + E+ G
Sbjct: 921 YKNCFLNLAIPIIVFTETSEVRKTEIRNGISFTIWDRWTVHGKEDFTLSDFINAVKENYG 980
Query: 407 LNAYSISCGSCLLFNSMFPRHKERM 333
+ + G +L+ + P H +R+
Sbjct: 981 IEPTMVVQGVKMLYVPVMPGHAKRL 1005
>sp|A0AVT1|UBA6_HUMAN Ubiquitin-like modifier-activating enzyme 6 OS=Homo
sapiens GN=UBA6 PE=1 SV=1
Length = 1052
Score = 141 bits (353), Expect = 1e-032
Identities = 90/265 (33%), Positives = 144/265 (54%), Gaps = 10/265 (3%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIPVPDWTKNPKEAAEAVDSVIVPDFEPREDAKI 927
P+++ ++P L+F+ A L A + IP + + + V + +F+P + +
Sbjct: 744 PIKFDLNEPLHLSFLQNAAKLYATVYCIPFAEEDLSADALLNILSEVKIQEFKP-SNKVV 802
Query: 926 VTDE---KATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDV 756
TDE K + +S D+ I L K D +M + FEKDDD N H+D
Sbjct: 803 QTDETARKPDHVPISSEDERNAIFQL-EKAILSNEATKSDLQMAVLSFEKDDDHNGHIDF 861
Query: 755 ISGLANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEA 576
I+ +N+RA+ YSI D+ K K IAG+IIPAIAT+TA +GLV LE+ KV GG+ EA
Sbjct: 862 ITAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATTTATVSGLVALEMIKV-TGGYPFEA 920
Query: 575 YRNTFANLALPLFSMAEPVPPKVVKHRD-MAWTVWDRWVLKGNP--TLREVLQWLEDK-G 408
Y+N F NLA+P+ E + K R+ +++T+WDRW + G TL + + +++K G
Sbjct: 921 YKNCFLNLAIPIVVFTETTEVRKTKIRNGISFTIWDRWTVHGKEDFTLLDFINAVKEKYG 980
Query: 407 LNAYSISCGSCLLFNSMFPRHKERM 333
+ + G +L+ + P H +R+
Sbjct: 981 IEPTMVVQGVKMLYVPVMPGHAKRL 1005
>sp|P41226|UBA7_HUMAN Ubiquitin-like modifier-activating enzyme 7 OS=Homo
sapiens GN=UBA7 PE=1 SV=2
Length = 1012
Score = 133 bits (333), Expect = 3e-030
Identities = 97/306 (31%), Positives = 162/306 (52%), Gaps = 18/306 (5%)
Frame = -1
Query: 1106 PLQYSSSDPSLLNFITATAILRAETFGIP-VPDWTKNPKEAAEAVDSVIVPDFEPREDAK 930
PL++ ++ + L ++ A A L A+ G+P DWT +E + ++P +P++ A
Sbjct: 714 PLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTA-LRELLK-----LLPQPDPQQMAP 767
Query: 929 IVTDEKATSLTTASVDDATVINDLIAKLERCRHNLSPDFRMKPVQFEKDDDTNYHMDVIS 750
I A++L AS A + +L + S +KP+ FEKDDD+N+H+D +
Sbjct: 768 IF----ASNLELASA-SAEFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVV 822
Query: 749 GLANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYR 570
A++R +NY IP V++ ++K I G+IIPAIAT+TA GL+ LELYKV+ G A+R
Sbjct: 823 AAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFR 882
Query: 569 NTFANLALPLFSMAEPVPPKVVKHRDMAWTVWDRW-VLKGNP--TLREVLQWLEDK-GLN 402
+++ +LA P P + + WT WDR V G P TL +L L+++ GL
Sbjct: 883 HSYLHLAENYLIRYMPFAPAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLR 942
Query: 401 AYSISCGSCLLFNSMFPRHK--ERMDKKVVDLARDIAKVELPPYRHHLDVVVACEDQDDN 228
+ GS LL+ + + K + + +V +L + + P + L + ++CE D++
Sbjct: 943 VRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDED 1002
Query: 227 DVDIPL 210
PL
Sbjct: 1003 TAFPPL 1008
>sp|Q54L40|SAE2_DICDI SUMO-activating enzyme subunit 2 OS=Dictyostelium
discoideum GN=uba2 PE=3 SV=1
Length = 661
Score = 56 bits (133), Expect = 5e-007
Identities = 30/85 (35%), Positives = 48/85 (56%), Gaps = 5/85 (5%)
Frame = -1
Query: 839 CRHNLSPDF---RMKPVQFEKDDDTNYHMDVISGLANMRARNYSIPEVDKLKAKFIAGRI 669
C L F KP+ ++KDD+ + + +N+R++ + IP + K +AG I
Sbjct: 322 CLEKLKQQFDQSNSKPMTWDKDDE--LALSFVCSASNIRSKIFGIPMKSRFDVKSMAGNI 379
Query: 668 IPAIATSTAMATGLVCLELYKVLDG 594
IPAIAT+ A+ GL+ +E KV+DG
Sbjct: 380 IPAIATTNAVIGGLIVMEAIKVVDG 404
>sp|Q9NAN1|SAE2_CAEEL SUMO-activating enzyme subunit uba-2 OS=Caenorhabditis
elegans GN=uba-2 PE=2 SV=3
Length = 582
Score = 54 bits (129), Expect = 1e-006
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 3/113 (2%)
Frame = -1
Query: 923 TDEKATSLTTASVDDATV--INDLIAKLERCRHNLSPDFRMKP-VQFEKDDDTNYHMDVI 753
T + SL A DD ++ ++ C L R +P V+ D D M +
Sbjct: 286 TGGEPQSLCDAQRDDTSIWTLSTCAKVFSTCIQELLEQIRAEPDVKLAFDKDHAIIMSFV 345
Query: 752 SGLANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDG 594
+ AN+RA+ + IP + K +AG IIPAIA++ A+ G++ E +V++G
Sbjct: 346 AACANIRAKIFGIPMKSQFDIKAMAGNIIPAIASTNAIVAGIIVTEAVRVIEG 398
>sp|Q28GH3|SAE2_XENTR SUMO-activating enzyme subunit 2 OS=Xenopus tropicalis
GN=uba2 PE=2 SV=1
Length = 641
Score = 54 bits (129), Expect = 1e-006
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Frame = -1
Query: 902 LTTASVDDATVINDLIAK-LERCRHNLSPDFRMKPVQFEKDDDTNYHMDVISGLANMRAR 726
L V D T L +K +E R L + ++KDD MD ++ AN+R
Sbjct: 305 LKDQKVLDVTSCAQLFSKSVETLREQLREKGNGAELVWDKDDPP--AMDFVTAAANLRMH 362
Query: 725 NYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYRNTFAN 555
+S+ + K +AG IIPAIAT+ A+ +GL+ LE K+L G E R F N
Sbjct: 363 IFSMNMKSRFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSG--NTEQCRTVFLN 417
>sp|Q9UBT2|SAE2_HUMAN SUMO-activating enzyme subunit 2 OS=Homo sapiens GN=UBA2
PE=1 SV=2
Length = 640
Score = 54 bits (127), Expect = 2e-006
Identities = 31/80 (38%), Positives = 47/80 (58%), Gaps = 4/80 (5%)
Frame = -1
Query: 794 FEKDDDTNYHMDVISGLANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLE 615
++KDD + MD ++ AN+R +S+ + K +AG IIPAIAT+ A+ GL+ LE
Sbjct: 344 WDKDDPS--AMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLE 401
Query: 614 LYKVLDGGHKVEAYRNTFAN 555
K+L G K++ R F N
Sbjct: 402 GLKILSG--KIDQCRTIFLN 419
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,759,707,213
Number of Sequences: 518415
Number of Extensions: 54759707213
Number of Successful Extensions: 366332288
Number of sequences better than 0.0: 0
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