BLASTX 7.6.2
Query= UN13382 /QuerySize=1448
(1447 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q4R5M2|CATB_MACFA Cathepsin B OS=Macaca fascicularis GN=CTSB ... 296 4e-079
sp|Q5R6D1|CATB_PONAB Cathepsin B OS=Pongo abelii GN=CTSB PE=2 SV=1 294 1e-078
sp|P07858|CATB_HUMAN Cathepsin B OS=Homo sapiens GN=CTSB PE=1 SV=3 293 2e-078
sp|P00787|CATB_RAT Cathepsin B OS=Rattus norvegicus GN=Ctsb PE=1... 285 5e-076
sp|P10605|CATB_MOUSE Cathepsin B OS=Mus musculus GN=Ctsb PE=1 SV=2 282 8e-075
sp|A1E295|CATB_PIG Cathepsin B OS=Sus scrofa GN=CTSB PE=1 SV=1 281 1e-074
sp|P43157|CYSP_SCHJA Cathepsin B-like cysteine proteinase OS=Sch... 262 5e-069
sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase OS=Caenorh... 258 9e-068
sp|P25792|CYSP_SCHMA Cathepsin B-like cysteine proteinase OS=Sch... 258 9e-068
sp|P25802|CYSP1_OSTOS Cathepsin B-like cysteine proteinase 1 OS=... 220 2e-056
sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5 OS=C... 171 1e-041
sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4 OS=C... 168 9e-041
sp|P07688|CATB_BOVIN Cathepsin B OS=Bos taurus GN=CTSB PE=1 SV=5 167 3e-040
sp|P43233|CATB_CHICK Cathepsin B OS=Gallus gallus GN=CTSB PE=2 SV=1 163 5e-039
sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6 OS=C... 162 7e-039
sp|P19092|CYSP1_HAECO Cathepsin B-like cysteine proteinase 1 OS=... 151 1e-035
sp|P25793|CYSP2_HAECO Cathepsin B-like cysteine proteinase 2 OS=... 150 3e-035
sp|Q06544|CYSP3_OSTOS Cathepsin B-like cysteine proteinase 3 (Fr... 144 2e-033
sp|P92133|CATB3_GIALA Cathepsin B-like CP3 OS=Giardia lamblia GN... 128 1e-028
sp|P92132|CATB2_GIALA Cathepsin B-like CP2 OS=Giardia lamblia GN... 118 1e-025
>sp|Q4R5M2|CATB_MACFA Cathepsin B OS=Macaca fascicularis GN=CTSB PE=2 SV=1
Length = 339
Score = 296 bits (756), Expect = 4e-079
Identities = 151/316 (47%), Positives = 196/316 (62%), Gaps = 28/316 (8%)
Frame = +3
Query: 282 LQDEIVKQVNENPKAGWKAAFNDRFANSTVAEFKRLLGVKPSPKNAFLGVPVVSHDISIS 461
L DE+V VN+ W+A N F N V+ KRL G FLG P + +
Sbjct: 26 LSDELVNYVNKQ-NTTWQAGHN--FYNVDVSYLKRLCG-------TFLGGPKPPQRVMFT 75
Query: 462 --LKLPKQFDARTAWSQCSSIGRILDQGHCGSCWAFGAVESLSDRFCIKYNMNISLSVN- 632
LKLP+ FDAR W QC +I I DQG CGSCWAFGAVE++SDR CI N ++S+ V+
Sbjct: 76 EDLKLPESFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSA 135
Query: 633 -DLLACCGFLCGQGCNGGYPISAWRYFKHHGVVT-------EECDPYF-----DNTGCSH 773
DLL CCG +CG GCNGGYP AW ++ G+V+ C PY + S
Sbjct: 136 EDLLTCCGIMCGDGCNGGYPAGAWNFWTRKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSR 195
Query: 774 PGCEPAYPTPKCVRKCVSG-NQLWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAFTV 950
P C TPKC + C G + +++ KHYG ++Y V + +DIMAE+Y NGPVE AF+V
Sbjct: 196 PPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV 255
Query: 951 YEDFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKR 1130
Y DF YKSGVY+H+TG +GGHA++++GWG ++G YWL+AN WN WGD+G+FKI R
Sbjct: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGV-ENGTPYWLVANSWNTDWGDNGFFKILR 314
Query: 1131 GTNECGIEHGVVAGLP 1178
G + CGIE VVAG+P
Sbjct: 315 GQDHCGIESEVVAGIP 330
>sp|Q5R6D1|CATB_PONAB Cathepsin B OS=Pongo abelii GN=CTSB PE=2 SV=1
Length = 339
Score = 294 bits (751), Expect = 1e-078
Identities = 150/316 (47%), Positives = 196/316 (62%), Gaps = 28/316 (8%)
Frame = +3
Query: 282 LQDEIVKQVNENPKAGWKAAFNDRFANSTVAEFKRLLGVKPSPKNAFLGVPVVSHDISIS 461
L DE+V VN+ W+A N F N V+ K+L G FLG P + +
Sbjct: 26 LSDELVNYVNKR-NTTWQAGHN--FYNVDVSYLKKLCG-------TFLGGPKPPQRVMFT 75
Query: 462 --LKLPKQFDARTAWSQCSSIGRILDQGHCGSCWAFGAVESLSDRFCIKYNMNISLSVN- 632
LKLP+ FDAR W QC +I I DQG CGSCWAFGAVE++SDR CI N ++S+ V+
Sbjct: 76 EDLKLPESFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSA 135
Query: 633 -DLLACCGFLCGQGCNGGYPISAWRYFKHHGVVT-------EECDPYF-----DNTGCSH 773
DLL CCG +CG GCNGGYP AW ++ G+V+ C PY + S
Sbjct: 136 EDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSR 195
Query: 774 PGCEPAYPTPKCVRKCVSG-NQLWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAFTV 950
P C TPKC + C G + +++ KHYG ++Y V + +DIMAE+Y NGPVE AF+V
Sbjct: 196 PPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSERDIMAEIYKNGPVEGAFSV 255
Query: 951 YEDFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKR 1130
Y DF YKSGVY+H+TG +GGHA++++GWG ++G YWL+AN WN WGD+G+FKI R
Sbjct: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGV-ENGTPYWLVANSWNTDWGDNGFFKILR 314
Query: 1131 GTNECGIEHGVVAGLP 1178
G + CGIE VVAG+P
Sbjct: 315 GQDHCGIESEVVAGIP 330
>sp|P07858|CATB_HUMAN Cathepsin B OS=Homo sapiens GN=CTSB PE=1 SV=3
Length = 339
Score = 293 bits (749), Expect = 2e-078
Identities = 150/316 (47%), Positives = 195/316 (61%), Gaps = 28/316 (8%)
Frame = +3
Query: 282 LQDEIVKQVNENPKAGWKAAFNDRFANSTVAEFKRLLGVKPSPKNAFLGVPVVSHDISIS 461
L DE+V VN+ W+A N F N ++ KRL G FLG P + +
Sbjct: 26 LSDELVNYVNKR-NTTWQAGHN--FYNVDMSYLKRLCG-------TFLGGPKPPQRVMFT 75
Query: 462 --LKLPKQFDARTAWSQCSSIGRILDQGHCGSCWAFGAVESLSDRFCIKYNMNISLSVN- 632
LKLP FDAR W QC +I I DQG CGSCWAFGAVE++SDR CI N ++S+ V+
Sbjct: 76 EDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSA 135
Query: 633 -DLLACCGFLCGQGCNGGYPISAWRYFKHHGVVT-------EECDPYF-----DNTGCSH 773
DLL CCG +CG GCNGGYP AW ++ G+V+ C PY + S
Sbjct: 136 EDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSR 195
Query: 774 PGCEPAYPTPKCVRKCVSG-NQLWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAFTV 950
P C TPKC + C G + +++ KHYG ++Y V + +DIMAE+Y NGPVE AF+V
Sbjct: 196 PPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV 255
Query: 951 YEDFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKR 1130
Y DF YKSGVY+H+TG +GGHA++++GWG ++G YWL+AN WN WGD+G+FKI R
Sbjct: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGV-ENGTPYWLVANSWNTDWGDNGFFKILR 314
Query: 1131 GTNECGIEHGVVAGLP 1178
G + CGIE VVAG+P
Sbjct: 315 GQDHCGIESEVVAGIP 330
>sp|P00787|CATB_RAT Cathepsin B OS=Rattus norvegicus GN=Ctsb PE=1 SV=2
Length = 339
Score = 285 bits (729), Expect = 5e-076
Identities = 146/325 (44%), Positives = 197/325 (60%), Gaps = 28/325 (8%)
Frame = +3
Query: 255 SNQKLTSPILQDEIVKQVNENPKAGWKAAFNDRFANSTVAEFKRLLGVKPSPKNAFLGVP 434
++ K +S L D+++ +N+ W+A N F N ++ K+L G LG P
Sbjct: 17 AHDKPSSHPLSDDMINYINKQ-NTTWQAGRN--FYNVDISYLKKLCG-------TVLGGP 66
Query: 435 VVSHDISIS--LKLPKQFDARTAWSQCSSIGRILDQGHCGSCWAFGAVESLSDRFCIKYN 608
+ + S + LP+ FDAR WS C +I +I DQG CGSCWAFGAVE++SDR CI N
Sbjct: 67 NLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTN 126
Query: 609 --MNISLSVNDLLACCGFLCGQGCNGGYPISAWRYFKHHGVVTE-------ECDPYF--- 752
+N+ +S DLL CCG CG GCNGGYP AW ++ G+V+ C PY
Sbjct: 127 GRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPP 186
Query: 753 --DNTGCSHPGCEPAYPTPKCVRKCVSG-NQLWRESKHYGVSAYKVRHDPQDIMAEVYTN 923
+ S P C TPKC + C +G + ++E KHYG ++Y V ++IMAE+Y N
Sbjct: 187 CEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKN 246
Query: 924 GPVEVAFTVYEDFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWG 1103
GPVE AFTV+ DF YKSGVYKH G +GGHA++++GWG ++G YWL+AN WN WG
Sbjct: 247 GPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGI-ENGVPYWLVANSWNVDWG 305
Query: 1104 DDGYFKIKRGTNECGIEHGVVAGLP 1178
D+G+FKI RG N CGIE +VAG+P
Sbjct: 306 DNGFFKILRGENHCGIESEIVAGIP 330
>sp|P10605|CATB_MOUSE Cathepsin B OS=Mus musculus GN=Ctsb PE=1 SV=2
Length = 339
Score = 282 bits (719), Expect = 8e-075
Identities = 142/318 (44%), Positives = 193/318 (60%), Gaps = 32/318 (10%)
Frame = +3
Query: 282 LQDEIVKQVNENPKAGWKAAFNDRFANSTVAEFKRLLGVKPSPKNAFLGVPVVSHDISI- 458
L D+++ +N+ W+A N F N ++ K+L G LG P + ++
Sbjct: 26 LSDDLINYINKQ-NTTWQAGRN--FYNVDISYLKKLCG-------TVLGGPKLPGRVAFG 75
Query: 459 -SLKLPKQFDARTAWSQCSSIGRILDQGHCGSCWAFGAVESLSDRFCIKYN--MNISLSV 629
+ LP+ FDAR WS C +IG+I DQG CGSCWAFGAVE++SDR CI N +N+ +S
Sbjct: 76 EDIDLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSA 135
Query: 630 NDLLACCGFLCGQGCNGGYPISAWRYFKHHGVVTEECDPYFDNTGC-------------- 767
DLL CCG CG GCNGGYP AW ++ G+V+ Y + GC
Sbjct: 136 EDLLTCCGIQCGDGCNGGYPSGAWSFWTKKGLVSG--GVYNSHVGCLPYTIPPCEHHVNG 193
Query: 768 SHPGCEPAYPTPKCVRKCVSG-NQLWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAF 944
S P C TP+C + C +G + ++E KH+G ++Y V + ++IMAE+Y NGPVE AF
Sbjct: 194 SRPPCTGEGDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAF 253
Query: 945 TVYEDFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKI 1124
TV+ DF YKSGVYKH G +GGHA++++GWG ++G YWL AN WN WGD+G+FKI
Sbjct: 254 TVFSDFLTYKSGVYKHEAGDMMGGHAIRILGWGV-ENGVPYWLAANSWNLDWGDNGFFKI 312
Query: 1125 KRGTNECGIEHGVVAGLP 1178
RG N CGIE +VAG+P
Sbjct: 313 LRGENHCGIESEIVAGIP 330
>sp|A1E295|CATB_PIG Cathepsin B OS=Sus scrofa GN=CTSB PE=1 SV=1
Length = 335
Score = 281 bits (718), Expect = 1e-074
Identities = 142/316 (44%), Positives = 191/316 (60%), Gaps = 28/316 (8%)
Frame = +3
Query: 282 LQDEIVKQVNENPKAGWKAAFNDRFANSTVAEFKRLLGVKPSPKNAFLGVPVVSHDISIS 461
L DE+V +N+ W A N F N ++ K+L G FLG P + + +
Sbjct: 26 LSDELVNFINKQ-NTTWTAGHN--FYNVDLSYVKKLCG-------TFLGGPKLPQRAAFA 75
Query: 462 --LKLPKQFDARTAWSQCSSIGRILDQGHCGSCWAFGAVESLSDRFCIKYN--MNISLSV 629
+ LPK FDAR W C +I I DQG CGSCWAFGAVE++SDR CI+ N +N+ +S
Sbjct: 76 ADMILPKSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIRSNGRVNVEVSA 135
Query: 630 NDLLACCGFLCGQGCNGGYPISAWRYFKHHGVVT-------EECDPYF-----DNTGCSH 773
D+L CCG CG GCNGG+P AW ++ G+V+ C PY + S
Sbjct: 136 EDMLTCCGDECGDGCNGGFPSGAWNFWTKKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSR 195
Query: 774 PGCEPAYPTPKCVRKCVSG-NQLWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAFTV 950
P C TPKC + C G ++E KH+G S+Y + + ++IMAE+Y NGPVE AFTV
Sbjct: 196 PPCTGEGDTPKCSKICEPGYTPSYKEDKHFGCSSYSISRNEKEIMAEIYKNGPVEGAFTV 255
Query: 951 YEDFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKR 1130
Y DF YKSGVY+H+TG +GGHA++++GWG ++G YWL+ N WN WGD+G+FKI R
Sbjct: 256 YSDFLQYKSGVYQHVTGDLMGGHAIRILGWGV-ENGTPYWLVGNSWNTDWGDNGFFKILR 314
Query: 1131 GTNECGIEHGVVAGLP 1178
G + CGIE +VAG+P
Sbjct: 315 GQDHCGIESEIVAGIP 330
>sp|P43157|CYSP_SCHJA Cathepsin B-like cysteine proteinase OS=Schistosoma
japonicum GN=CATB PE=2 SV=1
Length = 342
Score = 262 bits (669), Expect = 5e-069
Identities = 136/324 (41%), Positives = 196/324 (60%), Gaps = 24/324 (7%)
Frame = +3
Query: 255 SNQKLTSPILQDEIVKQVNENPKAGWKAAFNDRFANSTVAEFKRLLGV-KPSPKNAFLGV 431
+NQ++ L DE++ +NE+P AGWKA +DRF ++ + + L+G K +
Sbjct: 23 NNQRIEP--LSDEMISFINEHPDAGWKADKSDRF--HSLDDARILMGARKEDAEMKRNRR 78
Query: 432 PVVSHDISISLKLPKQFDARTAWSQCSSIGRILDQGHCGSCWAFGAVESLSDRFCIKY-- 605
P V H +++++P QFD+R W C SI +I DQ CGSCWAFGAVE+++DR CI+
Sbjct: 79 PTVDHH-DLNVEIPSQFDSRKKWPHCKSISQIRDQSRCGSCWAFGAVEAMTDRICIQSGG 137
Query: 606 NMNISLSVNDLLACCGFLCGQGCNGGYPISAWRYFKHHGVVT-------EECDPY----- 749
+ LS DL++CC CG GC GG+P AW Y+ G+VT C PY
Sbjct: 138 GQSAELSALDLISCCKD-CGDGCQGGFPGVAWDYWVKRGIVTGGSKENHTGCQPYPFPKC 196
Query: 750 FDNTGCSHPGC-EPAYPTPKCVRKCVSGNQL-WRESKHYGVSAYKVRHDPQDIMAEVYTN 923
+T +P C Y TP+C + C G + + + KHYG +Y V+++ + I ++
Sbjct: 197 EHHTKGKYPACGTKIYKTPQCKQTCQKGYKTPYEQDKHYGDESYNVQNNEKVIQRDIMMY 256
Query: 924 GPVEVAFTVYEDFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWG 1103
GPVE AF VYEDF +YKSG+Y+H+TG+ +GGHA+++IGWG + YWL+AN WN WG
Sbjct: 257 GPVEAAFDVYEDFLNYKSGIYRHVTGSIVGGHAIRIIGWGV-EKRTPYWLIANSWNEDWG 315
Query: 1104 DDGYFKIKRGTNECGIEHGVVAGL 1175
+ G F++ RG +EC IE VVAGL
Sbjct: 316 EKGLFRMVRGRDECSIESDVVAGL 339
>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase OS=Caenorhabditis elegans
GN=cpr-1 PE=1 SV=2
Length = 329
Score = 258 bits (658), Expect = 9e-068
Identities = 129/244 (52%), Positives = 156/244 (63%), Gaps = 12/244 (4%)
Frame = +3
Query: 468 LPKQFDARTAWSQCSSIGRILDQGHCGSCWAFGAVESLSDRFCI--KYNMNISLSVNDLL 641
+P FD+RT WS+C SI I DQ CGSCWAFGA E +SDR CI K +S +DLL
Sbjct: 85 VPATFDSRTQWSECKSIKLIRDQATCGSCWAFGAAEMISDRTCIETKGAQQPIISPDDLL 144
Query: 642 ACCGFLCGQGCNGGYPISAWRYFKHHGVVT------EECDPYFDNTGCSHPGCEPAYPTP 803
+CCG CG GC GGYPI A R++ GVVT C PY C+ C P TP
Sbjct: 145 SCCGSSCGNGCEGGYPIQALRWWDSKGVVTGGDYHGAGCKPY-PIAPCTSGNC-PESKTP 202
Query: 804 KCVRKCVSG-NQLWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAFTVYEDFAHYKSG 980
C C SG + + + KH+GVSAY V + I AE+Y NGPVE AF+VYEDF YKSG
Sbjct: 203 SCSMSCQSGYSTAYAKDKHFGVSAYAVPKNAASIQAEIYANGPVEAAFSVYEDFYKYKSG 262
Query: 981 VYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKRGTNECGIEHG 1160
VYKH G +GGHA+K+IGWGT + G YWL+AN W +WG+ G+FKI RG ++CGIE
Sbjct: 263 VYKHTAGKYLGGHAIKIIGWGT-ESGSPYWLVANSWGVNWGESGFFKIYRGDDQCGIESA 321
Query: 1161 VVAG 1172
VVAG
Sbjct: 322 VVAG 325
>sp|P25792|CYSP_SCHMA Cathepsin B-like cysteine proteinase OS=Schistosoma
mansoni PE=2 SV=1
Length = 340
Score = 258 bits (658), Expect = 9e-068
Identities = 134/313 (42%), Positives = 186/313 (59%), Gaps = 20/313 (6%)
Frame = +3
Query: 282 LQDEIVKQVNENPKAGWKAAFNDRFANSTVAEFKRLLGVKPSPKNAFLGVPVVSHDISIS 461
L D+I+ +NE+P AGW+A ++RF + A ++ + P P V H+ +
Sbjct: 29 LSDDIISYINEHPNAGWRAEKSNRFHSLDDARI-QMGARREEPDLRRKRRPTVDHN-DWN 86
Query: 462 LKLPKQFDARTAWSQCSSIGRILDQGHCGSCWAFGAVESLSDRFCIKY--NMNISLSVND 635
+++P FD+R W C SI I DQ CGSCW+FGAVE++SDR CI+ N+ LS D
Sbjct: 87 VEIPSNFDSRKKWPGCKSIATIRDQSRCGSCWSFGAVEAMSDRSCIQSGGKQNVELSAVD 146
Query: 636 LLACCGFLCGQGCNGGYPISAWRYFKHHGVVTEE-------CDPY-----FDNTGCSHPG 779
LL CC CG GC GG AW Y+ G+VT C+PY +T +P
Sbjct: 147 LLTCCE-SCGLGCEGGILGPAWDYWVKEGIVTASSKENHTGCEPYPFPKCEHHTKGKYPP 205
Query: 780 C-EPAYPTPKCVRKCVSGNQL-WRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAFTVY 953
C Y TP+C + C + + + KH G S+Y V++D + I E+ GPVE +FTVY
Sbjct: 206 CGSKIYNTPRCKQTCQRKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEASFTVY 265
Query: 954 EDFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKRG 1133
EDF +YKSG+YKHITG +GGHA+++IGWG ++ YWL+AN WN WG++GYF+I RG
Sbjct: 266 EDFLNYKSGIYKHITGEALGGHAIRIIGWGV-ENKTPYWLIANSWNEDWGENGYFRIVRG 324
Query: 1134 TNECGIEHGVVAG 1172
+EC IE V+AG
Sbjct: 325 RDECSIESEVIAG 337
>sp|P25802|CYSP1_OSTOS Cathepsin B-like cysteine proteinase 1 OS=Ostertagia
ostertagi GN=CP-1 PE=3 SV=3
Length = 341
Score = 220 bits (560), Expect = 2e-056
Identities = 106/251 (42%), Positives = 151/251 (60%), Gaps = 19/251 (7%)
Frame = +3
Query: 468 LPKQFDARTAWSQCSSIGRILDQGHCGSCWAFGAVESLSDRFCI--KYNMNISLSVNDLL 641
+P+ +D R W+ CSS+ I DQ +CGSCWA + ++SDR CI K + +S D++
Sbjct: 91 IPESYDPRIQWANCSSLFHIPDQANCGSCWAVSSAAAMSDRICIASKGAKQVLISAQDVV 150
Query: 642 ACCGFLCGQGCNGGYPISAWRYFKHHGVVT-------EECDPYFDNTGCSHPGCEPAY-- 794
+CC + CG GC GG+PISA+R+ GVVT C PY + C H G E Y
Sbjct: 151 SCCTW-CGDGCEGGWPISAFRFHADEGVVTGGDYNTKGSCRPY-EIHPCGHHGNETYYGE 208
Query: 795 -----PTPKCVRKCVSGNQLWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAFTVYED 959
TP+C R+C+ G S Y AY++++ + I ++ NGPV +TVYED
Sbjct: 209 CVGMADTPRCKRRCLLGYPKSYPSDRYYKKAYQLKNSVKAIQKDIMKNGPVVATYTVYED 268
Query: 960 FAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKRGTN 1139
FAHY+SG+YKH G G HAVK+IGWG + G YW++AN W+ WG++G+F++ RG+N
Sbjct: 269 FAHYRSGIYKHKAGRKTGLHAVKVIGWG-EEKGTPYWIVANSWHDDWGENGFFRMHRGSN 327
Query: 1140 ECGIEHGVVAG 1172
+CG E + AG
Sbjct: 328 DCGFEERMAAG 338
>sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5 OS=Caenorhabditis
elegans GN=cpr-5 PE=1 SV=1
Length = 344
Score = 171 bits (432), Expect = 1e-041
Identities = 79/143 (55%), Positives = 97/143 (67%), Gaps = 5/143 (3%)
Frame = +3
Query: 762 GCSHPGC-EPAYPTPKCVRKCVSGNQL---WRESKHYGVSAYKVRHDPQDIMAEVYTNGP 929
G P C E PTPKCV C S N + + KH+G +AY V + I E+ TNGP
Sbjct: 197 GVKWPACPEDTEPTPKCVDSCTSKNNYATPYLQDKHFGSTAYAVGKKVEQIQTEILTNGP 256
Query: 930 VEVAFTVYEDFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDD 1109
+EVAFTVYEDF Y +GVY H GA++GGHAVK++GWG D+G YWL+AN WN +WG+
Sbjct: 257 IEVAFTVYEDFYQYTTGVYVHTAGASLGGHAVKILGWGV-DNGTPYWLVANSWNVAWGEK 315
Query: 1110 GYFKIKRGTNECGIEHGVVAGLP 1178
GYF+I RG NECGIEH VAG+P
Sbjct: 316 GYFRIIRGLNECGIEHSAVAGIP 338
>sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4 OS=Caenorhabditis
elegans GN=cpr-4 PE=2 SV=1
Length = 335
Score = 168 bits (425), Expect = 9e-041
Identities = 76/138 (55%), Positives = 96/138 (69%), Gaps = 4/138 (2%)
Frame = +3
Query: 774 PGC-EPAYPTPKCVRKCVSGNQ--LWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAF 944
P C + Y TP CV KC + N + KH+G +AY V I AE+ +GPVE AF
Sbjct: 197 PSCPDDGYDTPACVNKCTNKNYNVAYTADKHFGSTAYAVGKKVSQIQAEIIAHGPVEAAF 256
Query: 945 TVYEDFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKI 1124
TVYEDF YK+GVY H TG +GGHA++++GWGT D+G YWL+AN WN +WG++GYF+I
Sbjct: 257 TVYEDFYQYKTGVYVHTTGQELGGHAIRILGWGT-DNGTPYWLVANSWNVNWGENGYFRI 315
Query: 1125 KRGTNECGIEHGVVAGLP 1178
RGTNECGIEH VV G+P
Sbjct: 316 IRGTNECGIEHAVVGGVP 333
>sp|P07688|CATB_BOVIN Cathepsin B OS=Bos taurus GN=CTSB PE=1 SV=5
Length = 335
Score = 167 bits (421), Expect = 3e-040
Identities = 76/164 (46%), Positives = 106/164 (64%), Gaps = 2/164 (1%)
Frame = +3
Query: 690 ISAWRYFKHHGVVTEECDPYFDNTGCSHPGCEPAYPTPKCVRKCVSG-NQLWRESKHYGV 866
+S Y H G P + S P C TPKC + C G + ++E KH+G
Sbjct: 168 VSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGC 227
Query: 867 SAYKVRHDPQDIMAEVYTNGPVEVAFTVYEDFAHYKSGVYKHITGANIGGHAVKLIGWGT 1046
S+Y V ++ ++IMAE+Y NGPVE AF+VY DF YKSGVY+H++G +GGHA++++GWG
Sbjct: 228 SSYSVANNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGV 287
Query: 1047 SDDGEDYWLLANQWNRSWGDDGYFKIKRGTNECGIEHGVVAGLP 1178
++G YWL+ N WN WGD+G+FKI RG + CGIE +VAG+P
Sbjct: 288 -ENGTPYWLVGNSWNTDWGDNGFFKILRGQDHCGIESEIVAGMP 330
>sp|P43233|CATB_CHICK Cathepsin B OS=Gallus gallus GN=CTSB PE=2 SV=1
Length = 340
Score = 163 bits (410), Expect = 5e-039
Identities = 77/165 (46%), Positives = 103/165 (62%), Gaps = 3/165 (1%)
Frame = +3
Query: 690 ISAWRYFKHHGVVTEECDPYFDNTGCSHPGCE-PAYPTPKCVRKCVSG-NQLWRESKHYG 863
+S Y H G P + S P C TP+C R C G + ++E KHYG
Sbjct: 168 VSGGLYDSHVGCRAYTIPPCEHHVNGSRPPCTGEGGETPRCSRHCEPGYSPSYKEDKHYG 227
Query: 864 VSAYKVRHDPQDIMAEVYTNGPVEVAFTVYEDFAHYKSGVYKHITGANIGGHAVKLIGWG 1043
+++Y V ++IMAE+Y NGPVE AF VYEDF YKSGVY+H++G +GGHA++++GWG
Sbjct: 228 ITSYGVPRSEKEIMAEIYKNGPVEGAFIVYEDFLMYKSGVYQHVSGEQVGGHAIRILGWG 287
Query: 1044 TSDDGEDYWLLANQWNRSWGDDGYFKIKRGTNECGIEHGVVAGLP 1178
++G YWL AN WN WG G+FKI RG + CGIE +VAG+P
Sbjct: 288 V-ENGTPYWLAANSWNTDWGITGFFKILRGEDHCGIESEIVAGVP 331
>sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6 OS=Caenorhabditis
elegans GN=cpr-6 PE=1 SV=1
Length = 379
Score = 162 bits (409), Expect = 7e-039
Identities = 75/131 (57%), Positives = 93/131 (70%), Gaps = 3/131 (2%)
Frame = +3
Query: 792 YPTPKCVRKCVSG--NQLWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAFTVYEDFA 965
YPTPKC +KCVS ++ + E K +G SAY V+ D + I E+ T+GP+E+AF VYEDF
Sbjct: 228 YPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFEVYEDFL 287
Query: 966 HYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKRGTNEC 1145
+Y GVY H G GGHAVKLIGWG DDG YW +AN WN WG+DG+F+I RG +EC
Sbjct: 288 NYDGGVYVHTGGKLGGGHAVKLIGWGI-DDGIPYWTVANSWNTDWGEDGFFRILRGVDEC 346
Query: 1146 GIEHGVVAGLP 1178
GIE GVV G+P
Sbjct: 347 GIESGVVGGIP 357
>sp|P19092|CYSP1_HAECO Cathepsin B-like cysteine proteinase 1 OS=Haemonchus
contortus GN=AC-1 PE=2 SV=1
Length = 342
Score = 151 bits (381), Expect = 1e-035
Identities = 68/133 (51%), Positives = 89/133 (66%), Gaps = 2/133 (1%)
Frame = +3
Query: 780 CEPAYPTPKCVRKCVSG-NQLWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAFTVYE 956
C PTP C RKC G +++R K YG AY V+ + I +E+ NGPV +F VYE
Sbjct: 205 CRGTAPTPPCKRKCRPGVRKMYRIDKRYGKDAYIVKQSVKAIQSEILRNGPVVASFAVYE 264
Query: 957 DFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKRGT 1136
DF HYKSG+YKH G G HAVK+IGWG +++ D+WL+AN W+ WG+ GYF+I RGT
Sbjct: 265 DFRHYKSGIYKHTAGELRGYHAVKMIGWG-NENNTDFWLIANSWHNDWGEKGYFRIIRGT 323
Query: 1137 NECGIEHGVVAGL 1175
N+CGIE + AG+
Sbjct: 324 NDCGIEGTIAAGI 336
>sp|P25793|CYSP2_HAECO Cathepsin B-like cysteine proteinase 2 OS=Haemonchus
contortus GN=AC-2 PE=2 SV=1
Length = 342
Score = 150 bits (378), Expect = 3e-035
Identities = 67/133 (50%), Positives = 89/133 (66%), Gaps = 2/133 (1%)
Frame = +3
Query: 780 CEPAYPTPKCVRKCVSG-NQLWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAFTVYE 956
C PTP C RKC G +++R K YG AY V+ + I +E+ NGPV +F VYE
Sbjct: 205 CRGTAPTPPCKRKCRPGVRKMYRIDKRYGKDAYIVKQSVKAIQSEILKNGPVVASFAVYE 264
Query: 957 DFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKRGT 1136
DF HYKSG+YKH G G HAVK+IGWG +++ D+WL+AN W+ WG+ GYF+I RG+
Sbjct: 265 DFRHYKSGIYKHTAGELRGYHAVKMIGWG-NENNTDFWLIANSWHNDWGEKGYFRIVRGS 323
Query: 1137 NECGIEHGVVAGL 1175
N+CGIE + AG+
Sbjct: 324 NDCGIEGTIAAGI 336
>sp|Q06544|CYSP3_OSTOS Cathepsin B-like cysteine proteinase 3 (Fragment)
OS=Ostertagia ostertagi GN=CP-3 PE=3 SV=1
Length = 174
Score = 144 bits (361), Expect = 2e-033
Identities = 64/133 (48%), Positives = 87/133 (65%), Gaps = 2/133 (1%)
Frame = +3
Query: 780 CEPAYPTPKCVRKCVSGN-QLWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAFTVYE 956
C TPKC + C G + ++E KH+G SAY++ ++ + I ++ NGPV F VYE
Sbjct: 42 CYDTAKTPKCQKTCQRGYLKAYKEDKHFGKSAYRLPNNVKAIQRDIMKNGPVVAGFIVYE 101
Query: 957 DFAHYKSGVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKRGT 1136
DFAHYKSG+YKH G GGHAVK+IGWG + G YWL+AN W+ WG+ G++++ RG
Sbjct: 102 DFAHYKSGIYKHTAGRMTGGHAVKIIGWG-KEKGTPYWLIANSWHDDWGEKGFYRMIRGI 160
Query: 1137 NECGIEHGVVAGL 1175
N C IE V AG+
Sbjct: 161 NNCRIEEMVFAGI 173
>sp|P92133|CATB3_GIALA Cathepsin B-like CP3 OS=Giardia lamblia GN=CP3 PE=2 SV=2
Length = 299
Score = 128 bits (321), Expect = 1e-028
Identities = 59/122 (48%), Positives = 75/122 (61%), Gaps = 2/122 (1%)
Frame = +3
Query: 807 CVRKCVSGNQLWRESKHYGVSAYKVRHDPQDIMAEVYTNGPVEVAFTVYEDFAHYKSGVY 986
C KC G+ L + A D IM + T GP++ AFTVY DF +Y+SGVY
Sbjct: 176 CPTKCADGSDL--PHLYKATKAVDYGLDAPAIMKALATGGPLQTAFTVYSDFMYYESGVY 233
Query: 987 KHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKRGTNECGIEHGVV 1166
+H G GGHAV ++G+GT DDG DYW++ N W WG+DGYF+I R TNECGIE V+
Sbjct: 234 QHTYGRVEGGHAVDMVGYGTDDDGVDYWIIKNSWGPDWGEDGYFRIIRMTNECGIEEQVI 293
Query: 1167 AG 1172
G
Sbjct: 294 GG 295
>sp|P92132|CATB2_GIALA Cathepsin B-like CP2 OS=Giardia lamblia GN=CP2 PE=1 SV=2
Length = 300
Score = 118 bits (295), Expect = 1e-025
Identities = 56/125 (44%), Positives = 78/125 (62%), Gaps = 8/125 (6%)
Frame = +3
Query: 807 CVRKCVSGNQLWRESKHYGVSAYKVRHDPQDI---MAEVYTNGPVEVAFTVYEDFAHYKS 977
C KC G+ SK + +A + DI M + T+GP++VAF V+ DF +Y+S
Sbjct: 177 CPTKCADGS-----SKVHLATATSYKDYGLDIPAMMKALSTSGPLQVAFLVHSDFMYYES 231
Query: 978 GVYKHITGANIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIKRGTNECGIEH 1157
GVY+H G GGHAV+++G+GT DDG DYW++ N W WG+DGYF++ RG N+C IE
Sbjct: 232 GVYQHTYGYMEGGHAVEMVGYGTDDDGVDYWIIKNSWGPDWGEDGYFRMIRGINDCSIEE 291
Query: 1158 GVVAG 1172
AG
Sbjct: 292 QAYAG 296
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,759,707,213
Number of Sequences: 518415
Number of Extensions: 54759707213
Number of Successful Extensions: 366332288
Number of sequences better than 0.0: 0
|
