BLASTX 7.6.2
Query= UN13452 /QuerySize=1024
(1023 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O48962|EBP_ARATH Probable 3-beta-hydroxysteroid-Delta(8),Delt... 377 1e-103
sp|Q9FTZ2|EBP_ORYSJ Probable 3-beta-hydroxysteroid-Delta(8),Delt... 275 4e-073
sp|Q60490|EBP_CAVPO 3-beta-hydroxysteroid-Delta(8),Delta(7)-isom... 140 2e-032
sp|P70245|EBP_MOUSE 3-beta-hydroxysteroid-Delta(8),Delta(7)-isom... 137 2e-031
sp|Q9JJ46|EBP_RAT 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomer... 136 3e-031
sp|Q15125|EBP_HUMAN 3-beta-hydroxysteroid-Delta(8),Delta(7)-isom... 128 7e-029
sp|Q9D0P0|EBPL_MOUSE Emopamil-binding protein-like OS=Mus muscul... 106 3e-022
sp|Q9BY08|EBPL_HUMAN Emopamil-binding protein-like OS=Homo sapie... 104 2e-021
sp|Q55E32|EBP_DICDI Probable 3-beta-hydroxysteroid-Delta(8),Delt... 57 2e-007
>sp|O48962|EBP_ARATH Probable 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
OS=Arabidopsis thaliana GN=At1g20050 PE=2 SV=1
Length = 223
Score = 377 bits (966), Expect = 1e-103
Identities = 182/222 (81%), Positives = 196/222 (88%), Gaps = 4/222 (1%)
Frame = +1
Query: 130 EAAAHPYVPRDLKLPGYVPISMSMSSILAVYLGASLFVVTFVWFLLGRKKAHLDRLLMCW 309
E AHPYVPRDL LPGYVPISMSMSSI+++YLG+SL VV+ VW L GRKKA LD+LLMCW
Sbjct: 2 EELAHPYVPRDLNLPGYVPISMSMSSIVSIYLGSSLLVVSLVWLLFGRKKAKLDKLLMCW 61
Query: 310 WAFTGLTHMVLEGYFVFSPEFFKDNTSCYLAEVWKEYSKGDSRYAGRDSAVIAVEGITAV 489
W FTGLTH++LEGYFVFSPEFFKDNTS YLAEVWKEYSKGDSRY GRDSAV++VEGITAV
Sbjct: 62 WTFTGLTHVILEGYFVFSPEFFKDNTSAYLAEVWKEYSKGDSRYVGRDSAVVSVEGITAV 121
Query: 490 IEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFLEGDNFATNSFYYYSYY 669
I GPASLLA+YAIAK KSYSYVLQLAIS+ QLYGCLVYFITA LEGDNFATNSFYYYSYY
Sbjct: 122 IVGPASLLAIYAIAKEKSYSYVLQLAISVCQLYGCLVYFITAILEGDNFATNSFYYYSYY 181
Query: 670 ICANGWWVLIPFLISYRCWNKICASP----NGVETKIKKKTR 783
I AN WWVLIP LIS+RCW KICA+ N VETK KKKTR
Sbjct: 182 IGANCWWVLIPSLISFRCWKKICAAAAIANNNVETKTKKKTR 223
>sp|Q9FTZ2|EBP_ORYSJ Probable 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
OS=Oryza sativa subsp. japonica GN=Os01g0103600 PE=2 SV=1
Length = 219
Score = 275 bits (702), Expect = 4e-073
Identities = 128/213 (60%), Positives = 158/213 (74%), Gaps = 3/213 (1%)
Frame = +1
Query: 142 HPYVPRDLKLPGYVPISMSMSSILAVYLGASLFVVTFVWFLLGRKKAHL---DRLLMCWW 312
HPY P +L LPG+VP+ +S + IL YL SLF++ VW + GR L DR LMCWW
Sbjct: 7 HPYAPAELHLPGFVPLQLSQAQILVPYLATSLFLLLAVWLISGRCSRRLSDTDRWLMCWW 66
Query: 313 AFTGLTHMVLEGYFVFSPEFFKDNTSCYLAEVWKEYSKGDSRYAGRDSAVIAVEGITAVI 492
AFTGLTH+++EG FVF+P FF + Y EVWKEYSKGDSRY RD A + VEGITAV+
Sbjct: 67 AFTGLTHIIIEGTFVFAPNFFSNQNPSYFDEVWKEYSKGDSRYVARDPATVTVEGITAVL 126
Query: 493 EGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFLEGDNFATNSFYYYSYYI 672
EGPASLLAVYAIA GKSYS++LQ + LGQLYGCLVYFITA+L+G NF T+ FY+++Y+I
Sbjct: 127 EGPASLLAVYAIASGKSYSHILQFTVCLGQLYGCLVYFITAYLDGFNFWTSPFYFWAYFI 186
Query: 673 CANGWWVLIPFLISYRCWNKICASPNGVETKIK 771
AN WV+IP +I+ R W KICA+ G + K K
Sbjct: 187 GANSSWVVIPTMIAIRSWKKICAAFQGEKVKTK 219
>sp|Q60490|EBP_CAVPO 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase OS=Cavia
porcellus GN=EBP PE=1 SV=3
Length = 229
Score = 140 bits (351), Expect = 2e-032
Identities = 77/217 (35%), Positives = 119/217 (54%), Gaps = 7/217 (3%)
Frame = +1
Query: 142 HPYVPRDLKLPGYVPISMSMSSILAVYLGASLFVVTFVWFLLGRKK----AHLDRLLMCW 309
HPY PR L+L +VP +S I+ V +V +W L R RL +CW
Sbjct: 10 HPYWPRHLRLDHFVPNDLSAWYIVTVLFTVFGALVVTMWLLSSRASVVPLGTWRRLSVCW 69
Query: 310 WAFTGLTHMVLEGYFVFSPEFFKDNTSCYLAEVWKEYSKGDSRYAGRDSAVIAVEGITAV 489
+A H+V+EG+FV + + +L+++WKEY+KGDSRY D+ +I +E IT V
Sbjct: 70 FAVCAFVHLVIEGWFVLYQKAILGD-QAFLSQLWKEYAKGDSRYIIEDNFIICMESITVV 128
Query: 490 IEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFLEGDNFAT--NSFYYYS 663
+ GP SL AV A + YVLQ ISLGQ+YG L+YF+T + +G + Y++
Sbjct: 129 LWGPLSLWAVIAFLRQHPSRYVLQFVISLGQIYGDLLYFLTEYRDGFQHGEMGHPIYFWF 188
Query: 664 YYICANGWWVLIPFLISYRCWNKICASPNGVETKIKK 774
Y+ N W++IP ++ + + + N ++TK+ K
Sbjct: 189 YFFFMNVLWLVIPGVLFFDSVKQFYGAQNALDTKVMK 225
>sp|P70245|EBP_MOUSE 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase OS=Mus
musculus GN=Ebp PE=1 SV=3
Length = 230
Score = 137 bits (343), Expect = 2e-031
Identities = 74/218 (33%), Positives = 122/218 (55%), Gaps = 9/218 (4%)
Frame = +1
Query: 142 HPYVPRDLKLPGYVPISMSMSSILAVYLGASLFVVTFVWFLLGRKK----AHLDRLLMCW 309
HPY PR LKL +VP + S IL S ++ W L R RL +CW
Sbjct: 9 HPYWPRHLKLDNFVPNDLPTSHILVGLFSISGGLIVITWLLSSRASVVPLGAGRRLALCW 68
Query: 310 WAFTGLTHMVLEGYF-VFSPEFFKDNTSCYLAEVWKEYSKGDSRYAGRDSAVIAVEGITA 486
+A H+V+EG+F +++ +D +L+++WKEYSKGDSRY DS V+ +E +TA
Sbjct: 69 FAVCTFIHLVIEGWFSLYNGILLED--QAFLSQLWKEYSKGDSRYILSDSFVVCMETVTA 126
Query: 487 VIEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFLEGDNFAT--NSFYYY 660
+ GP SL V A + + + +VLQL +S+GQ+YG ++YF+T EG + Y++
Sbjct: 127 CLWGPLSLWVVIAFLRQQPFRFVLQLVVSMGQIYGDVLYFLTELHEGLQHGEIGHPVYFW 186
Query: 661 SYYICANGWWVLIPFLISYRCWNKICASPNGVETKIKK 774
Y++ N W++IP ++ + ++ + +++K+ K
Sbjct: 187 FYFVFLNAVWLVIPSILVLDAIKHLTSAQSVLDSKVMK 224
>sp|Q9JJ46|EBP_RAT 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase OS=Rattus
norvegicus GN=Ebp PE=2 SV=3
Length = 230
Score = 136 bits (341), Expect = 3e-031
Identities = 70/217 (32%), Positives = 118/217 (54%), Gaps = 7/217 (3%)
Frame = +1
Query: 142 HPYVPRDLKLPGYVPISMSMSSILAVYLGASLFVVTFVWFLLGRKK----AHLDRLLMCW 309
HPY PR L+L +VP + IL S ++ W L R RL +CW
Sbjct: 9 HPYWPRHLRLDNFVPNDLPTWHILVGLFSFSGVLIVITWLLSSRVSVVPLGTGRRLALCW 68
Query: 310 WAFTGLTHMVLEGYFVFSPEFFKDNTSCYLAEVWKEYSKGDSRYAGRDSAVIAVEGITAV 489
+A H+V+EG+F F E ++ +L+++WKEYSKGDSRY D ++ +E +TA
Sbjct: 69 FAVCTFIHLVIEGWFSFYHEILLED-QAFLSQLWKEYSKGDSRYILSDGFIVCMESVTAC 127
Query: 490 IEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFLEGDNFAT--NSFYYYS 663
+ GP SL V A + + + +VLQL +S+GQ+YG ++YF+T +G + Y++
Sbjct: 128 LWGPLSLWVVIAFLRHQPFRFVLQLVVSVGQIYGDVLYFLTELRDGFQHGELGHPLYFWF 187
Query: 664 YYICANGWWVLIPFLISYRCWNKICASPNGVETKIKK 774
Y++ N W++IP ++ + + + + ++ K+ K
Sbjct: 188 YFVIMNAIWLVIPGILVFDAIKHLTNAQSMLDNKVMK 224
>sp|Q15125|EBP_HUMAN 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase OS=Homo
sapiens GN=EBP PE=1 SV=3
Length = 230
Score = 128 bits (321), Expect = 7e-029
Identities = 68/195 (34%), Positives = 108/195 (55%), Gaps = 11/195 (5%)
Frame = +1
Query: 142 HPYVPRDLKLPGYVPISMSMSSILAVYLGASLFVVTFVWFLLGRKK----AHLDRLLMCW 309
HPY P+ L+L +VP ILA + +V W L GR RL +CW
Sbjct: 9 HPYWPQHLRLDNFVPNDRPTWHILAGLFSVTGVLVVTTWLLSGRAAVVPLGTWRRLSLCW 68
Query: 310 WAFTGLTHMVLEGYFVFSPEFFKD--NTSCYLAEVWKEYSKGDSRYAGRDSAVIAVEGIT 483
+A G H+V+EG+FV +++D +L+++WKEY+KGDSRY D+ + +E IT
Sbjct: 69 FAVCGFIHLVIEGWFVL---YYEDLLGDQAFLSQLWKEYAKGDSRYILGDNFTVCMETIT 125
Query: 484 AVIEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFLEGDNFAT--NSFYY 657
A + GP SL V A + ++LQL +S+GQ+YG ++YF+T +G + Y+
Sbjct: 126 ACLWGPLSLWVVIAFLRQHPLRFILQLVVSVGQIYGDVLYFLTEHRDGFQHGELGHPLYF 185
Query: 658 YSYYICANGWWVLIP 702
+ Y++ N W+++P
Sbjct: 186 WFYFVFMNALWLVLP 200
>sp|Q9D0P0|EBPL_MOUSE Emopamil-binding protein-like OS=Mus musculus GN=Ebpl PE=2
SV=1
Length = 206
Score = 106 bits (264), Expect = 3e-022
Identities = 55/157 (35%), Positives = 91/157 (57%), Gaps = 3/157 (1%)
Frame = +1
Query: 265 LGRKKAHLDRLLMCWWAFTGLTHMVLEGYFVF-SPEFFKDNTSCYLAEVWKEYSKGDSRY 441
LGR ++ ++R ++ W + L H VLEG FV+ S ++ +A +WKEY K D+R+
Sbjct: 32 LGRGRSAVERWVLAWLCYDSLVHFVLEGAFVYLSIVGNVADSQGLIASLWKEYGKADTRW 91
Query: 442 AGRDSAVIAVEGITAVIEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFL 621
D V+++E +T V++G +L+ +YAI K K Y + +Q+ + + +LYGC + F +L
Sbjct: 92 LYSDPTVVSLEILTVVLDGLLALVLIYAIVKEKYYRHFVQIVLCVCELYGCWMTFFPEWL 151
Query: 622 EGDNFATNS--FYYYSYYICANGWWVLIPFLISYRCW 726
G S Y + Y + NG WVLIP L+ ++ W
Sbjct: 152 VGSPSLNTSSWLYLWVYLVFFNGLWVLIPGLLLWQSW 188
>sp|Q9BY08|EBPL_HUMAN Emopamil-binding protein-like OS=Homo sapiens GN=EBPL PE=1
SV=1
Length = 206
Score = 104 bits (257), Expect = 2e-021
Identities = 58/173 (33%), Positives = 94/173 (54%), Gaps = 3/173 (1%)
Frame = +1
Query: 265 LGRKKAHLDRLLMCWWAFTGLTHMVLEGYFVF-SPEFFKDNTSCYLAEVWKEYSKGDSRY 441
LGR + DR + W + L H LEG FV+ S N+ +A +WKEY K D+R+
Sbjct: 32 LGRGQGAADRGALIWLCYDALVHFALEGPFVYLSLVGNVANSDGLIASLWKEYGKADARW 91
Query: 442 AGRDSAVIAVEGITAVIEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFL 621
D +++VE +T ++G +L +YAI K K Y + LQ+ + + +LYGC + F+ +L
Sbjct: 92 VYFDPTIVSVEILTVALDGSLALFLIYAIVKEKYYRHFLQITLCVCELYGCWMTFLPEWL 151
Query: 622 -EGDNFATNSFYY-YSYYICANGWWVLIPFLISYRCWNKICASPNGVETKIKK 774
N T+++ Y + Y NG WVLIP L+ ++ W ++ + +KK
Sbjct: 152 TRSPNLNTSNWLYCWLYLFFFNGVWVLIPGLLLWQSWLELKKMHQKETSSVKK 204
>sp|Q55E32|EBP_DICDI Probable 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
OS=Dictyostelium discoideum GN=ebp PE=2 SV=1
Length = 219
Score = 57 bits (135), Expect = 2e-007
Identities = 37/140 (26%), Positives = 70/140 (50%), Gaps = 4/140 (2%)
Frame = +1
Query: 394 YLAEVWKEYSKGDSRYAGRDSAVIAVEGITAVIEGPASLLAVYAIAKGKSYSYVLQLAIS 573
+ A+++ +Y+K D RYA +D V+ +++G A L V + K + LQ+ +
Sbjct: 80 WYAQLYSQYAKYDLRYAIQDPMVVFF-CFLELVQGAACFLLVICVIKQARIRHALQIFLC 138
Query: 574 LGQLYGCLVYFITAFLEG---DNFATNSFYYYSYYICANGWWVLIPFLISYRCWNKICAS 744
Q G + YFIT ++ G +++ F + Y + NG W+L+P +++ + + I
Sbjct: 139 SIQGLGTVFYFITPYIYGLWEQQISSDPFELWVYVVGLNGLWLLVPIILTIQSFIAINKQ 198
Query: 745 PNGVETKIKKKTR*NAKKKT 804
+ VE+ K + K KT
Sbjct: 199 FSIVESTTKDAKFISRKPKT 218
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,759,707,213
Number of Sequences: 518415
Number of Extensions: 54759707213
Number of Successful Extensions: 366332288
Number of sequences better than 0.0: 0
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