BLASTX 7.6.2
Query= UN13612 /QuerySize=2101
(2100 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9ZVM9|Y1461_ARATH Probable serine/threonine-protein kinase A... 1013 1e-294
sp|Q5JK68|CDKC2_ORYSJ Cyclin-dependent kinase C-2 OS=Oryza sativ... 276 6e-073
sp|Q6I5Y0|CDKC1_ORYSJ Cyclin-dependent kinase C-1 OS=Oryza sativ... 269 8e-071
sp|Q8W4P1|CDKC2_ARATH Cyclin-dependent kinase C-2 OS=Arabidopsis... 268 1e-070
sp|Q9LFT8|CDKC1_ARATH Cyclin-dependent kinase C-1 OS=Arabidopsis... 267 2e-070
sp|O14098|CTK1_SCHPO CTD kinase subunit alpha OS=Schizosaccharom... 244 2e-063
sp|Q9NYV4|CDK12_HUMAN Cell division protein kinase 12 OS=Homo sa... 215 2e-054
sp|Q14AX6|CDK12_MOUSE Cell division protein kinase 12 OS=Mus mus... 213 4e-054
sp|Q3MJK5|CDK12_RAT Cell division protein kinase 12 OS=Rattus no... 213 4e-054
sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sa... 213 7e-054
sp|Q69ZA1|CDK13_MOUSE Cell division protein kinase 13 OS=Mus mus... 212 9e-054
sp|Q5R7I7|CDK20_PONAB Cell division protein kinase 20 OS=Pongo a... 208 2e-052
sp|Q8IZL9|CDK20_HUMAN Cell division protein kinase 20 OS=Homo sa... 207 3e-052
sp|Q9JHU3|CDK20_MOUSE Cell division protein kinase 20 OS=Mus mus... 201 2e-050
sp|Q4KM34|CDK20_RAT Cell division protein kinase 20 OS=Rattus no... 198 2e-049
sp|A8WIP6|CDK20_DANRE Cell division protein kinase 20 OS=Danio r... 190 5e-047
sp|P42525|ERK1_DICDI Extracellular signal-regulated kinase 1 OS=... 176 5e-043
sp|Q556J6|Y4007_DICDI Putative cyclin-dependent serine/threonine... 165 2e-039
sp|Q9U9Y8|NLK_CAEEL Serine/threonine kinase NLK OS=Caenorhabditi... 150 4e-035
sp|Q9UBE8|NLK_HUMAN Serine/threonine-protein kinase NLK OS=Homo ... 148 3e-034
>sp|Q9ZVM9|Y1461_ARATH Probable serine/threonine-protein kinase At1g54610
OS=Arabidopsis thaliana GN=At1g54610 PE=1 SV=1
Length = 572
Score = 1013 bits (2617), Expect = 1e-294
Identities = 497/556 (89%), Positives = 524/556 (94%), Gaps = 4/556 (0%)
Frame = -2
Query: 1877 SSSKAATTSEIKLAKTSKT-GETVQASDVEKKKHDEEEAPPPKEDKKPSKGDRRRSTKPN 1701
+ S A++ + + ++S T V A DVEKKK++E +++K SKGDRRRSTKPN
Sbjct: 20 AKSSKASSGVVVVGESSVTKSNGVIADDVEKKKNEEANG---DKERKSSKGDRRRSTKPN 76
Query: 1700 PRLSNPSKHWRGEQVAAGWPSWLSDACGEALNGWVPRKADTFEKIDKIGQGTYSNVYKAK 1521
PRLSNPSKHWRGEQVAAGWPSWLSDACGEALNGWVPRKADTFEKIDKIGQGTYSNVYKAK
Sbjct: 77 PRLSNPSKHWRGEQVAAGWPSWLSDACGEALNGWVPRKADTFEKIDKIGQGTYSNVYKAK 136
Query: 1520 DMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLDHPNVVKLEGLVTSRMSCSLYLVF 1341
DMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLDHPNVVKLEGLVTSRMSCSLYLVF
Sbjct: 137 DMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLDHPNVVKLEGLVTSRMSCSLYLVF 196
Query: 1340 QYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCHSRGVLHRDIKGSNLLIDDGGVL 1161
QYMDHDLAGLASSP+V FS+ EVKCLMRQL+SG+EHCHSRGVLHRDIKGSNLLIDDGGVL
Sbjct: 197 QYMDHDLAGLASSPVVKFSESEVKCLMRQLISGLEHCHSRGVLHRDIKGSNLLIDDGGVL 256
Query: 1160 KIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILAELLAGR 981
KIADFGLATIFDPNHKR MTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILAELLAGR
Sbjct: 257 KIADFGLATIFDPNHKRPMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILAELLAGR 316
Query: 980 PIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFTHGAIYKPREPYPRCIRETFKDFPPSSL 801
PIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFTHGAIYKPREPY R IRETFKDFPPSSL
Sbjct: 317 PIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFTHGAIYKPREPYKRSIRETFKDFPPSSL 376
Query: 800 PLIDSLLSIEPENRQTATAALHSEFFTSDPYACEPADLPKYPPSKEMDAKRRDEETRRQR 621
PLID+LLSIEPE+RQTA+AAL SEFFTS+PYACEPADLPKYPPSKE+DAKRRDEETRRQR
Sbjct: 377 PLIDALLSIEPEDRQTASAALKSEFFTSEPYACEPADLPKYPPSKEIDAKRRDEETRRQR 436
Query: 620 AASKAQGDGARKNRHRDRSNRALPAPEANAELQSNVDRRRLITHATAKSKSEKFPPPHQD 441
AASKAQGDGARKNRHRDRSNRALPAPEANAELQSNVDRRRLITHA AKSKSEKFPPPHQD
Sbjct: 437 AASKAQGDGARKNRHRDRSNRALPAPEANAELQSNVDRRRLITHANAKSKSEKFPPPHQD 496
Query: 440 GGAMGVPLGASQHIDPTFVPPDMASSFTSTSFNFSKDEPPTQVQTWSGPLGHPITGISRR 261
GGAMGVPLGASQHIDPTF+P DM SFTS+SFNFSKDEPPTQVQTWSGPLGHPITG+SR+
Sbjct: 497 GGAMGVPLGASQHIDPTFIPRDMVPSFTSSSFNFSKDEPPTQVQTWSGPLGHPITGVSRK 556
Query: 260 KKDSTKSSKGKRAVMA 213
KKD+TKSSKGKRAV+A
Sbjct: 557 KKDNTKSSKGKRAVVA 572
>sp|Q5JK68|CDKC2_ORYSJ Cyclin-dependent kinase C-2 OS=Oryza sativa subsp.
japonica GN=CDKC-2 PE=2 SV=1
Length = 513
Score = 276 bits (704), Expect = 6e-073
Identities = 141/319 (44%), Positives = 194/319 (60%), Gaps = 6/319 (1%)
Frame = -2
Query: 1358 SLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCHSRGVLHRDIKGSNLLI 1179
S+Y+VF+YMDHDL GLA P + F+ P++KC MRQLL+G+ +CH VLHRDIKGSNLLI
Sbjct: 113 SIYMVFEYMDHDLTGLADRPGMRFTVPQIKCYMRQLLTGLHYCHVNQVLHRDIKGSNLLI 172
Query: 1178 DDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILA 999
D+ G LK+ADFGLA F +H +T+RV+TLWYR PELLLG+T YG +D+WS GCI A
Sbjct: 173 DNEGNLKLADFGLARSFSSDHNGNLTNRVITLWYRPPELLLGSTRYGPAVDMWSVGCIFA 232
Query: 998 ELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWK-KGKFTHGAIYKPREPYPRCIRETFK 822
ELL G+PI+ G+ E EQL KI++LCG+P E W K +KP+ P R ++E+FK
Sbjct: 233 ELLNGKPILTGKNEPEQLSKIFELCGTPDELIWPGVTKMPWYNNFKPQRPMKRRVKESFK 292
Query: 821 DFPPSSLPLIDSLLSIEPENRQTATAALHSEFFTSDPYACEPADLPKYPPSKEMDAKRRD 642
F +L L++ +L+++P R +A AL +E+F +DP C+P LPKY S E K++
Sbjct: 293 HFDQHALDLLEKMLTLDPSQRISAKDALDAEYFWTDPLPCDPKSLPKYEASHEFQTKKKR 352
Query: 641 EETRRQRAASKAQGDGARKNRHRDRSNRALPAPEANAELQSNVDRRRLITHATAKSKSEK 462
++ R+ A+K Q K +H +R P Q + A S
Sbjct: 353 QQQRQAEEAAKRQ-----KLQHPPPHSRLPPIQNPGQPHQIRPGQPMHNAPPVAAGPSHH 407
Query: 461 FPPPHQDGGAMGVPLGASQ 405
+ P GG P G +Q
Sbjct: 408 YAKPRGPGGPNRYPQGGNQ 426
>sp|Q6I5Y0|CDKC1_ORYSJ Cyclin-dependent kinase C-1 OS=Oryza sativa subsp.
japonica GN=CDKC-1 PE=2 SV=1
Length = 519
Score = 269 bits (686), Expect = 8e-071
Identities = 141/321 (43%), Positives = 193/321 (60%), Gaps = 8/321 (2%)
Frame = -2
Query: 1358 SLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCHSRGVLHRDIKGSNLLI 1179
S+Y+VF+YMDHDL GLA P + F+ P++KC M+QLL+G+ +CH VLHRDIKGSNLLI
Sbjct: 113 SIYMVFEYMDHDLTGLADRPGMRFTVPQIKCYMKQLLTGLHYCHINQVLHRDIKGSNLLI 172
Query: 1178 DDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILA 999
D+ G LK+ADFGLA F +H +T+RV+TLWYR PELLLG+T YG +D+WS GCI A
Sbjct: 173 DNEGNLKLADFGLARSFSNDHNGNLTNRVITLWYRPPELLLGSTKYGPAVDMWSVGCIFA 232
Query: 998 ELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWK-KGKFTHGAIYKPREPYPRCIRETFK 822
ELL G+PI+PG+ E EQL KI+ +CG+P E W K +KP R ++E FK
Sbjct: 233 ELLNGKPILPGKNEPEQLSKIFDVCGTPDESNWPGVTKMPWYNNFKPPRQLKRRVKEYFK 292
Query: 821 DFPPSSLPLIDSLLSIEPENRQTATAALHSEFFTSDPYACEPADLPKYPPSKEMDAKRRD 642
F +L L++ +L+++P R +A AL +E+F SDP C+P LPKY S E K++
Sbjct: 293 HFDRLALDLLEKMLTLDPAQRISAQDALDAEYFWSDPLPCDPKSLPKYESSHEFQTKKKR 352
Query: 641 EETRRQRAASKAQGDGARKNRHRDRSNRALPAPE-ANAELQSNVDRRRLITHA-TAKSKS 468
++ R+ A+K Q K +H R P + Q + HA A
Sbjct: 353 QQMRQADEAAKRQ-----KTQHPQPHGRLPPIQQTGQPHPQIRPGQPMNNPHAPMAAGPG 407
Query: 467 EKFPPPHQDGGAMGVPLGASQ 405
+ P GG+ P G +Q
Sbjct: 408 HHYAKPRGPGGSSRYPQGGNQ 428
>sp|Q8W4P1|CDKC2_ARATH Cyclin-dependent kinase C-2 OS=Arabidopsis thaliana
GN=CDKC-2 PE=1 SV=2
Length = 513
Score = 268 bits (685), Expect = 1e-070
Identities = 135/281 (48%), Positives = 183/281 (65%), Gaps = 7/281 (2%)
Frame = -2
Query: 1355 LYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCHSRGVLHRDIKGSNLLID 1176
+Y+VF+YMDHDL GLA P + F+ P++KC M+QLL+G+ +CH VLHRDIKGSNLLID
Sbjct: 114 IYMVFEYMDHDLTGLADRPGLRFTVPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLID 173
Query: 1175 DGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILAE 996
+ G LK+ADFGLA + +H +T+RV+TLWYR PELLLGAT YG ID+WS GCI AE
Sbjct: 174 NEGNLKLADFGLARSYSHDHTGNLTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAE 233
Query: 995 LLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWK-KGKFTHGAIYKPREPYPRCIRETFKD 819
LL G+PI+PG+TE EQL+KIY+LCGSP E W K K P R +RE ++
Sbjct: 234 LLNGKPILPGKTENEQLNKIYELCGSPDESNWPGVSKMPWYNQMKSSRPLKRRVREIYRH 293
Query: 818 FPPSSLPLIDSLLSIEPENRQTATAALHSEFFTSDPYACEPADLPKYPPSKEMDAKRRDE 639
F +L L++ +L ++P R A AL +E+F +DP C+P LP Y S E K++ +
Sbjct: 294 FDRHALELLEKMLVLDPSQRICAKDALDAEYFWTDPLPCDPKSLPTYESSHEFQTKKKRQ 353
Query: 638 ETRRQRAASKAQGDGARKNRHRDRSNRALPAPEANAELQSN 516
+ R A+K Q K +H + + LP P+ + QS+
Sbjct: 354 QMRHNEEAAKKQ-----KLQHPQQQHSRLP-PQQHGVGQSH 388
>sp|Q9LFT8|CDKC1_ARATH Cyclin-dependent kinase C-1 OS=Arabidopsis thaliana
GN=CDKC-1 PE=1 SV=1
Length = 505
Score = 267 bits (682), Expect = 2e-070
Identities = 127/252 (50%), Positives = 172/252 (68%), Gaps = 1/252 (0%)
Frame = -2
Query: 1355 LYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCHSRGVLHRDIKGSNLLID 1176
+Y+VF+YMDHDL GLA P + F+ P++KC M+QLL+G+ +CH VLHRDIKGSNLLID
Sbjct: 114 IYMVFEYMDHDLTGLADRPGLRFTVPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLID 173
Query: 1175 DGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILAE 996
+ G LK+ADFGLA + +H +T+RV+TLWYR PELLLGAT YG ID+WS GCI AE
Sbjct: 174 NEGNLKLADFGLARSYSHDHTGNLTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAE 233
Query: 995 LLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWK-KGKFTHGAIYKPREPYPRCIRETFKD 819
LL +PI+PG+ E EQL+KI++LCGSP E W K +KP P R +RE F+
Sbjct: 234 LLHAKPILPGKNEQEQLNKIFELCGSPDEKLWPGVSKMPWFNNFKPARPLKRRVREFFRH 293
Query: 818 FPPSSLPLIDSLLSIEPENRQTATAALHSEFFTSDPYACEPADLPKYPPSKEMDAKRRDE 639
F +L L++ +L ++P R +A AL +E+F +DP C+P LP Y S E K++ +
Sbjct: 294 FDRHALELLEKMLVLDPAQRISAKDALDAEYFWTDPLPCDPKSLPTYESSHEFQTKKKRQ 353
Query: 638 ETRRQRAASKAQ 603
+ R+ A+K Q
Sbjct: 354 QQRQNEEAAKRQ 365
>sp|O14098|CTK1_SCHPO CTD kinase subunit alpha OS=Schizosaccharomyces pombe
GN=lsk1 PE=1 SV=1
Length = 593
Score = 244 bits (622), Expect = 2e-063
Identities = 150/395 (37%), Positives = 219/395 (55%), Gaps = 17/395 (4%)
Frame = -2
Query: 1805 ASDVEKKKHDEEEAPPPKEDK----KPSKGDRRRSTKPNPRLSNPSKHWRGEQVAAGWPS 1638
+SD +KK P K K P++ R P+ R++ S E V A P
Sbjct: 204 SSDTQKKSSVSSGFPENKHGKFHFHIPNERRSRFDQPPSKRMALTST--ARESVPAPLP- 260
Query: 1637 WLSDACGEALNGWVPRKADTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPE 1458
S G P+ A +EKID+IG+GTY VYKA + +TG +VALK++R + +
Sbjct: 261 --SPPSGPIYTYTYPKPA--YEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDG 316
Query: 1457 SVKFMAREILVLRRLDHPNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPLVNFSQP 1278
RE+ +L+RL H N+V+L ++ + S+Y+VF+YMDHDL G+ + ++F+
Sbjct: 317 FPITTVREVKILQRLRHKNIVRLLEIMVEK--SSVYMVFEYMDHDLTGVLLNSQLHFTPG 374
Query: 1277 EVKCLMRQLLSGMEHCHSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRAMTS 1098
+K L +Q+ + + H RGVLHRDIKGSN+L+++ G LK ADFGLA + T+
Sbjct: 375 NIKHLSKQIFEALAYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTN 434
Query: 1097 RVVTLWYRAPELLLGATDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGS 918
RV+TLW+R PELLLG T Y +D+WSAGCI+ EL G+P GR E+ QL IY + G+
Sbjct: 435 RVITLWFRPPELLLGETAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGT 494
Query: 917 PSEDYWKKGK-FTHGAIYKPREPYPRCIRETFKD-FPPSSLPLIDSLLSIEPENRQTATA 744
P W + K + KP E ETFK+ P+++ L LL++ P R +A
Sbjct: 495 PDVHSWPEVKNLPWYELLKPVEEKKSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHE 554
Query: 743 ALHSEFFTSDPYACEPADLPKYPPSK--EMDAKRR 645
L E+FTS+ EPA + K E ++K+R
Sbjct: 555 TLMHEYFTSESPPPEPAVILKNMQGSWHEWESKKR 589
>sp|Q9NYV4|CDK12_HUMAN Cell division protein kinase 12 OS=Homo sapiens GN=CDK12
PE=1 SV=1
Length = 1490
Score = 215 bits (545), Expect = 2e-054
Identities = 110/248 (44%), Positives = 153/248 (61%), Gaps = 6/248 (2%)
Frame = -2
Query: 1358 SLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCHSRGVLHRDIKGSNLLI 1179
+ YLVF+YMDHDL GL S LV+FS+ +K M+QL+ G+E+CH + LHRDIK SN+L+
Sbjct: 808 AFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILL 867
Query: 1178 DDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILA 999
++ G +K+ADFGLA +++ R T++V+TLWYR PELLLG Y ID+WS GCIL
Sbjct: 868 NNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILG 927
Query: 998 ELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKG-KFTHGAIYKPREPYPRCIRETFK 822
EL +PI E+ QL I +LCGSP W K + KP++ Y R +RE F
Sbjct: 928 ELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFS 987
Query: 821 DFPPSSLPLIDSLLSIEPENRQTATAALHSEFFTS-DPYACEPADLPKYPPSKEMDAKRR 645
P ++L L+D +L+++P R TA L S+F + P DLP + E+ +K+R
Sbjct: 988 FIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKR 1047
Query: 644 DEETRRQR 621
RRQR
Sbjct: 1048 ----RRQR 1051
>sp|Q14AX6|CDK12_MOUSE Cell division protein kinase 12 OS=Mus musculus GN=Cdk12
PE=1 SV=2
Length = 1484
Score = 213 bits (542), Expect = 4e-054
Identities = 109/248 (43%), Positives = 153/248 (61%), Gaps = 6/248 (2%)
Frame = -2
Query: 1358 SLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCHSRGVLHRDIKGSNLLI 1179
+ YLVF+YMDHDL GL S LV+FS+ +K M+QL+ G+++CH + LHRDIK SN+L+
Sbjct: 804 AFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILL 863
Query: 1178 DDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILA 999
++ G +K+ADFGLA +++ R T++V+TLWYR PELLLG Y ID+WS GCIL
Sbjct: 864 NNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILG 923
Query: 998 ELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKG-KFTHGAIYKPREPYPRCIRETFK 822
EL +PI E+ QL I +LCGSP W K + KP++ Y R +RE F
Sbjct: 924 ELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFS 983
Query: 821 DFPPSSLPLIDSLLSIEPENRQTATAALHSEFFTS-DPYACEPADLPKYPPSKEMDAKRR 645
P ++L L+D +L+++P R TA L S+F + P DLP + E+ +K+R
Sbjct: 984 FIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKR 1043
Query: 644 DEETRRQR 621
RRQR
Sbjct: 1044 ----RRQR 1047
>sp|Q3MJK5|CDK12_RAT Cell division protein kinase 12 OS=Rattus norvegicus
GN=Cdk12 PE=1 SV=1
Length = 1484
Score = 213 bits (542), Expect = 4e-054
Identities = 109/248 (43%), Positives = 153/248 (61%), Gaps = 6/248 (2%)
Frame = -2
Query: 1358 SLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCHSRGVLHRDIKGSNLLI 1179
+ YLVF+YMDHDL GL S LV+FS+ +K M+QL+ G+++CH + LHRDIK SN+L+
Sbjct: 804 AFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILL 863
Query: 1178 DDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILA 999
++ G +K+ADFGLA +++ R T++V+TLWYR PELLLG Y ID+WS GCIL
Sbjct: 864 NNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILG 923
Query: 998 ELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKG-KFTHGAIYKPREPYPRCIRETFK 822
EL +PI E+ QL I +LCGSP W K + KP++ Y R +RE F
Sbjct: 924 ELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFS 983
Query: 821 DFPPSSLPLIDSLLSIEPENRQTATAALHSEFFTS-DPYACEPADLPKYPPSKEMDAKRR 645
P ++L L+D +L+++P R TA L S+F + P DLP + E+ +K+R
Sbjct: 984 FIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKR 1043
Query: 644 DEETRRQR 621
RRQR
Sbjct: 1044 ----RRQR 1047
>sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13
PE=1 SV=2
Length = 1512
Score = 213 bits (540), Expect = 7e-054
Identities = 112/267 (41%), Positives = 156/267 (58%), Gaps = 6/267 (2%)
Frame = -2
Query: 1358 SLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCHSRGVLHRDIKGSNLLI 1179
+ YLVF+YMDHDL GL S LV+F++ +K MRQL+ G+++CH + LHRDIK SN+L+
Sbjct: 786 AFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILL 845
Query: 1178 DDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILA 999
++ G +K+ADFGLA ++ R T++V+TLWYR PELLLG Y ID+WS GCIL
Sbjct: 846 NNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILG 905
Query: 998 ELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKG-KFTHGAIYKPREPYPRCIRETFK 822
EL +PI E+ QL I ++CGSP W K + KP++ Y R +RE F
Sbjct: 906 ELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFV 965
Query: 821 DFPPSSLPLIDSLLSIEPENRQTATAALHSEFFTS-DPYACEPADLPKYPPSKEMDAKRR 645
P ++L L D +L+++P R TA AL EF +P P DLP + E+ +K+R
Sbjct: 966 FIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKR 1025
Query: 644 DEETRRQRAASKAQGDGARKNRHRDRS 564
RRQ+ K +D S
Sbjct: 1026 ----RRQKQMGMTDDVSTIKAPRKDLS 1048
>sp|Q69ZA1|CDK13_MOUSE Cell division protein kinase 13 OS=Mus musculus GN=Cdk13
PE=1 SV=2
Length = 1511
Score = 212 bits (539), Expect = 9e-054
Identities = 109/248 (43%), Positives = 152/248 (61%), Gaps = 6/248 (2%)
Frame = -2
Query: 1358 SLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCHSRGVLHRDIKGSNLLI 1179
+ YLVF+YMDHDL GL S LV+F++ +K MRQL+ G+++CH + LHRDIK SN+L+
Sbjct: 786 AFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILL 845
Query: 1178 DDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILA 999
++ G +K+ADFGLA ++ R T++V+TLWYR PELLLG Y ID+WS GCIL
Sbjct: 846 NNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILG 905
Query: 998 ELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKG-KFTHGAIYKPREPYPRCIRETFK 822
EL +PI E+ QL I ++CGSP W K + KP++ Y R +RE F
Sbjct: 906 ELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFV 965
Query: 821 DFPPSSLPLIDSLLSIEPENRQTATAALHSEFFTS-DPYACEPADLPKYPPSKEMDAKRR 645
P ++L L D +L+++P R TA AL EF +P P DLP + E+ +K+R
Sbjct: 966 FIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKR 1025
Query: 644 DEETRRQR 621
RRQ+
Sbjct: 1026 ----RRQK 1029
>sp|Q5R7I7|CDK20_PONAB Cell division protein kinase 20 OS=Pongo abelii GN=CDK20
PE=2 SV=1
Length = 346
Score = 208 bits (527), Expect = 2e-052
Identities = 117/304 (38%), Positives = 170/304 (55%), Gaps = 8/304 (2%)
Frame = -2
Query: 1583 DTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRL-DH 1407
D + + +IG+G + V+KAK + TG+IVALKKV LE REI L+ + D+
Sbjct: 2 DQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEMEDN 61
Query: 1406 PNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCH 1227
VV+L+ + S L F++M DLA + +Q +VK ++ LL G+ CH
Sbjct: 62 QYVVQLKAVFPH--SAGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVSFCH 119
Query: 1226 SRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGAT 1047
+ ++HRD+K +NLLI G LKIADFGLA +F P+ R T +V T WYRAPELL GA
Sbjct: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
Query: 1046 DYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFTHGAIY 867
Y G+DLW+ GCI+ ELL G P+ PG+ ++EQL + ++ G+P+ W + T Y
Sbjct: 180 QYDQGVDLWAVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWP--ELTELPDY 237
Query: 866 KP---REPYPRCIRETFKDFPPSSLPLIDSLLSIEPENRQTATAALHSEFFTSDPYACEP 696
+E P + E D P +L L+ L P R A+ AL ++F + P P
Sbjct: 238 NKISFKEQAPVPLEEVLPDASPQALDLLGQFLLYPPRQRIAASKALLHQYFFTAPLPAHP 297
Query: 695 ADLP 684
++LP
Sbjct: 298 SELP 301
>sp|Q8IZL9|CDK20_HUMAN Cell division protein kinase 20 OS=Homo sapiens GN=CDK20
PE=1 SV=1
Length = 346
Score = 207 bits (526), Expect = 3e-052
Identities = 117/304 (38%), Positives = 169/304 (55%), Gaps = 8/304 (2%)
Frame = -2
Query: 1583 DTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRL-DH 1407
D + + +IG+G + V+KAK + TG+IVALKKV LE REI L+ + D+
Sbjct: 2 DQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDN 61
Query: 1406 PNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCH 1227
VV+L+ + L F++M DLA + +Q +VK ++ LL G+ CH
Sbjct: 62 QYVVQLKAVFPH--GGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
Query: 1226 SRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGAT 1047
+ ++HRD+K +NLLI G LKIADFGLA +F P+ R T +V T WYRAPELL GA
Sbjct: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
Query: 1046 DYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFTHGAIY 867
Y G+DLWS GCI+ ELL G P+ PG+ ++EQL + ++ G+P+ W + T Y
Sbjct: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWP--ELTELPDY 237
Query: 866 KP---REPYPRCIRETFKDFPPSSLPLIDSLLSIEPENRQTATAALHSEFFTSDPYACEP 696
+E P + E D P +L L+ L P R A+ AL ++F + P P
Sbjct: 238 NKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHP 297
Query: 695 ADLP 684
++LP
Sbjct: 298 SELP 301
>sp|Q9JHU3|CDK20_MOUSE Cell division protein kinase 20 OS=Mus musculus GN=Cdk20
PE=1 SV=1
Length = 346
Score = 201 bits (510), Expect = 2e-050
Identities = 116/304 (38%), Positives = 166/304 (54%), Gaps = 8/304 (2%)
Frame = -2
Query: 1583 DTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRL-DH 1407
D + + +IG+G + V+KAK + TG+IVALKKV LE REI L+ + D
Sbjct: 2 DQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDS 61
Query: 1406 PNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCH 1227
VV+L+ + L F++M DLA + + +VK ++ LL G+ CH
Sbjct: 62 QYVVQLKAVFPH--GAGFVLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCH 119
Query: 1226 SRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGAT 1047
+ ++HRD+K +NLLI G LKIADFGLA +F P+ R T +V T WYRAPELL GA
Sbjct: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGAR 179
Query: 1046 DYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFTHGAIY 867
Y G+DLW+ GCI+ ELL G P+ PG ++EQL + ++ G+PS W + T Y
Sbjct: 180 QYDQGVDLWAVGCIMGELLNGSPLFPGENDIEQLCCVLRILGTPSPRVWP--EITELPDY 237
Query: 866 KP---REPYPRCIRETFKDFPPSSLPLIDSLLSIEPENRQTATAALHSEFFTSDPYACEP 696
+E P + E D P +L L+ L P R A+ AL ++F + P P
Sbjct: 238 NKISFKEQAPVPLEEVLPDASPQALDLLGQFLLYPPRQRIAASQALLHQYFFTAPLPAHP 297
Query: 695 ADLP 684
++LP
Sbjct: 298 SELP 301
>sp|Q4KM34|CDK20_RAT Cell division protein kinase 20 OS=Rattus norvegicus
GN=Cdk20 PE=2 SV=2
Length = 346
Score = 198 bits (501), Expect = 2e-049
Identities = 115/304 (37%), Positives = 165/304 (54%), Gaps = 8/304 (2%)
Frame = -2
Query: 1583 DTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRL-DH 1407
D + + +IG+G + V+KAK + TG+IVALKKV LE REI L+ + D
Sbjct: 2 DQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDS 61
Query: 1406 PNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCH 1227
VV+L+ + L F++M DLA + + +VK ++ LL G+ CH
Sbjct: 62 QYVVQLKAVFPH--GAGFVLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCH 119
Query: 1226 SRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGAT 1047
+ ++HRD+K +NLLI G LKIADFGLA +F P+ R T +V T WYRAPELL GA
Sbjct: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGAR 179
Query: 1046 DYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFTHGAIY 867
Y G+DLW+ GCI+ ELL G P+ PG ++EQL + ++ G+PS W + T Y
Sbjct: 180 QYDQGVDLWAVGCIMGELLNGSPLFPGENDIEQLCCVLRILGTPSPRVWP--EITELPDY 237
Query: 866 KP---REPYPRCIRETFKDFPPSSLPLIDSLLSIEPENRQTATAALHSEFFTSDPYACEP 696
+E P + E D +L L+ L P R A+ AL ++F + P P
Sbjct: 238 NKISFKEQAPVPLEEVLPDASHQALDLLGQFLLYPPRQRIAASQALLHQYFFTAPLPAHP 297
Query: 695 ADLP 684
++LP
Sbjct: 298 SELP 301
>sp|A8WIP6|CDK20_DANRE Cell division protein kinase 20 OS=Danio rerio GN=cdk20
PE=2 SV=1
Length = 344
Score = 190 bits (481), Expect = 5e-047
Identities = 113/308 (36%), Positives = 163/308 (52%), Gaps = 16/308 (5%)
Frame = -2
Query: 1583 DTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRL-DH 1407
D + + +IG+G + V+KAK + TG+ VALKKV LE REI L+ + D+
Sbjct: 2 DQYSILGRIGEGAHGIVFKAKHIETGETVALKKVALRRLEDGIPNQALREIKALQEIEDN 61
Query: 1406 PNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCH 1227
VVKL+ + LVF+YM DL+ + + + +VK M LL G+ CH
Sbjct: 62 QYVVKLKDVFPH--GTGFVLVFEYMLSDLSEVIRNSQRPLTASQVKSYMMMLLKGVAFCH 119
Query: 1226 SRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGAT 1047
++HRD+K +NLLI G LKIADFGLA +F R + +V T WYRAPELL GA
Sbjct: 120 ENSIMHRDLKPANLLISSTGHLKIADFGLARLFSNEGDRLYSHQVATRWYRAPELLYGAR 179
Query: 1046 DYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKK-------GK 888
Y G+DLW+ GCI ELL P+ PG ++EQL + ++ G+P++ W + K
Sbjct: 180 KYDEGVDLWAVGCIFGELLNNSPLFPGENDIEQLCCVLRVLGTPNQKVWPEITELPDYNK 239
Query: 887 FTHGAIYKPREPYPRCIRETFKDFPPSSLPLIDSLLSIEPENRQTATAALHSEFFTSDPY 708
T +K P P + E D P ++ L+ L + R +A AL +F +DP
Sbjct: 240 IT----FKENPPIP--LEEIVPDTSPQAVDLLKKFLVYPSKQRISARQALLHPYFFTDPL 293
Query: 707 ACEPADLP 684
++LP
Sbjct: 294 PAHHSELP 301
>sp|P42525|ERK1_DICDI Extracellular signal-regulated kinase 1 OS=Dictyostelium
discoideum GN=erkA PE=2 SV=2
Length = 529
Score = 176 bits (446), Expect = 5e-043
Identities = 119/332 (35%), Positives = 175/332 (52%), Gaps = 24/332 (7%)
Frame = -2
Query: 1598 VPRKADTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKV--RFDNLEPESVKFMAREILV 1425
VPR+ + + IG G Y V AKD LTG+ VA+KK+ FDNL + K REI +
Sbjct: 145 VPRR---YSIVKCIGHGAYGVVCSAKDNLTGEKVAIKKISKAFDNL--KDTKRTLREIHL 199
Query: 1424 LRRLDHPNVVKLEGLV---TSRMSCSLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQ 1254
LR H N++ ++ ++ + +Y+V + MD DL + +SP S + + Q
Sbjct: 200 LRHFKHENLISIKDILKPNSKEQFEDVYIVSELMDTDLHQIITSP-QPLSDDHCQYFVYQ 258
Query: 1253 LLSGMEHCHSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYR 1074
+L G++H HS VLHRD+K SNLLI++ +LKI D GLA + D H+ MT V T WYR
Sbjct: 259 MLRGLKHIHSANVLHRDLKPSNLLINEDCLLKICDLGLARVEDATHQGFMTEYVATRWYR 318
Query: 1073 APELLLGATDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSED---- 906
APE++L Y ID+WS GCI AELL +P+ G+ + Q+ I + GSPSE+
Sbjct: 319 APEVILSWNKYTKAIDIWSVGCIFAELLGRKPLFQGKDYIHQITLIIETIGSPSEEDICN 378
Query: 905 --YWKKGKFTHGAIYKPREPYPRCIRETFKDFPPSSLPLIDSLLSIEPENRQTATAALHS 732
+ +F +P+ + F P ++ L++ +L +P R T AL
Sbjct: 379 IANEQARQFIRNMGNQPKVNF----ANMFPKANPDAIDLLERMLYFDPSKRLTVEEALAH 434
Query: 731 EFFTS--DPYACEPADLPKYPPSKEMDAKRRD 642
+F S DP + EP L K+ + E RD
Sbjct: 435 PYFQSLHDP-SDEPICLHKFSLNFEAWDLNRD 465
>sp|Q556J6|Y4007_DICDI Putative cyclin-dependent serine/threonine-protein kinase
DDB_G0272797/DDB_G0274007 OS=Dictyostelium discoideum GN=DDB_G0272797
PE=3 SV=1
Length = 680
Score = 165 bits (416), Expect = 2e-039
Identities = 90/226 (39%), Positives = 135/226 (59%), Gaps = 9/226 (3%)
Frame = -2
Query: 1568 IDKIGQGTYSNVYKAKDMLTGKIVALKKV---RFDNLEPESVKFMAREILVLRRLDHPNV 1398
+ K GQGTY +V+K +T +VALK+V ++ EP VK++ + L+ L N+
Sbjct: 7 LSKCGQGTYGSVFKGIHKITHSLVALKRVTDIAQEDGEPVEVKYLNQ----LKNLS--NI 60
Query: 1397 VKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCHSRG 1218
V L + L L+ ++++ DL + S+P S ++K +QLL G++ CH G
Sbjct: 61 VNLRDHFYIDKNSVLVLIMEFIEGDLWKIMSNPQCTLSLGQIKNFTKQLLEGVKQCHVNG 120
Query: 1217 VLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGATDYG 1038
++HRDIK +NLLI GVLK+ DFGL+T + ++ ++S VV+L+YR PELLLG+ YG
Sbjct: 121 IMHRDIKPANLLITTNGVLKLTDFGLSTSYSKRSEKFLSSNVVSLYYRPPELLLGSCIYG 180
Query: 1037 VGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYW 900
ID+WS GCIL E++ + G E QL I+KL G P+E W
Sbjct: 181 PEIDMWSVGCILMEMINNSYLFAGADETAQLDLIFKLFGCPTEKSW 226
>sp|Q9U9Y8|NLK_CAEEL Serine/threonine kinase NLK OS=Caenorhabditis elegans
GN=lit-1 PE=1 SV=1
Length = 634
Score = 150 bits (378), Expect = 4e-035
Identities = 102/288 (35%), Positives = 149/288 (51%), Gaps = 13/288 (4%)
Frame = -2
Query: 1559 IGQGTYSNVYKAKDMLTGKIVALKKVR--FDNLEPESVKFMAREILVLRRLDHPNVVKLE 1386
IG G + V+ D +GK VALKK+ F NL S K + REI +L H NV+ L
Sbjct: 246 IGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNL--ASCKRVFREIKMLSSFRHDNVLSLL 303
Query: 1385 GLV---TSRMSCSLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQLLSGMEHCHSRGV 1215
++ LY++ + M DL + SP + VK + Q+L G+++ H+ +
Sbjct: 304 DILQPANPSFFQELYVLTELMQSDLHKIIVSPQA-LTPDHVKVFVYQILRGLKYLHTANI 362
Query: 1214 LHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRAPELLLGATDYGV 1035
LHRDIK NLL++ +LKI DFGLA +D + MT VVT +YRAPELL+GA Y
Sbjct: 363 LHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGARRYTG 422
Query: 1034 GIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWK---KGKFTHGAIYK 864
+D+WS GCI AELL + + +EQL I L G+PS++ K +G H
Sbjct: 423 AVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAG 482
Query: 863 PREPYPRCIRETFK--DFPPSSLPLIDSLLSIEPENRQTATAALHSEF 726
R P + + + D ++ L+ LL +P+ R + AL +
Sbjct: 483 LRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRY 530
>sp|Q9UBE8|NLK_HUMAN Serine/threonine-protein kinase NLK OS=Homo sapiens GN=NLK
PE=1 SV=2
Length = 527
Score = 148 bits (371), Expect = 3e-034
Identities = 104/294 (35%), Positives = 153/294 (52%), Gaps = 11/294 (3%)
Frame = -2
Query: 1595 PRKADTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVR--FDNLEPESVKFMAREILVL 1422
P++ E IG G + V+ D GK VALKK+ F NL S K + RE+ +L
Sbjct: 132 PQQQLDIEPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNL--VSCKRVFRELKML 189
Query: 1421 RRLDHPNVVK-LEGLVTSRMSC--SLYLVFQYMDHDLAGLASSPLVNFSQPEVKCLMRQL 1251
H NV+ L+ L + +Y+V + M DL + SP S VK + Q+
Sbjct: 190 CFFKHDNVLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSP-QPLSSDHVKVFLYQI 248
Query: 1250 LSGMEHCHSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRAMTSRVVTLWYRA 1071
L G+++ HS G+LHRDIK NLL++ VLKI DFGLA + + + R MT VVT +YRA
Sbjct: 249 LRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRA 308
Query: 1070 PELLLGATDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWK-- 897
PE+L+G+ Y ID+WS GCI AELL R + ++ ++QL I L G+PS + +
Sbjct: 309 PEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTA 368
Query: 896 -KGKFTHGAIYKPREPYPRCIRETFKDFPPSSLPLIDSLLSIEPENRQTATAAL 738
+G H ++P + ++ L+ +L +P R +A AL
Sbjct: 369 CEGAKAHILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDAL 422
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,759,707,213
Number of Sequences: 518415
Number of Extensions: 54759707213
Number of Successful Extensions: 366332288
Number of sequences better than 0.0: 0
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