BLASTX 7.6.2
Query= UN13634 /QuerySize=1137
(1136 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9M077|AUR1_ARATH Serine/threonine-protein kinase Aurora-1 OS... 561 4e-159
sp|Q683C9|AUR2_ARATH Serine/threonine-protein kinase Aurora-2 OS... 536 2e-151
sp|O64629|AUR3_ARATH Serine/threonine-protein kinase Aurora-3 OS... 378 4e-104
sp|Q9N0X0|AURKB_PIG Serine/threonine-protein kinase 12 OS=Sus sc... 372 4e-102
sp|Q91819|STK6L_XENLA Serine/threonine-protein kinase Eg2-like O... 369 3e-101
sp|Q6GPL3|AUKBB_XENLA Serine/threonine-protein kinase 12-B OS=Xe... 369 3e-101
sp|Q91820|STK6_XENLA Serine/threonine-protein kinase 6 OS=Xenopu... 368 6e-101
sp|P97477|STK6_MOUSE Serine/threonine-protein kinase 6 OS=Mus mu... 367 8e-101
sp|Q6DE08|AUKBA_XENLA Serine/threonine-protein kinase 12-A OS=Xe... 364 6e-100
sp|P59241|STK6_RAT Serine/threonine-protein kinase 6 OS=Rattus n... 364 8e-100
sp|Q96GD4|AURKB_HUMAN Serine/threonine-protein kinase 12 OS=Homo... 364 1e-099
sp|A4IGM9|AURKB_XENTR Serine/threonine-protein kinase 12 OS=Xeno... 363 2e-099
sp|Q2TA06|STK6_BOVIN Serine/threonine-protein kinase 6 OS=Bos ta... 362 2e-099
sp|A5GFW1|STK6_PIG Serine/threonine-protein kinase 6 OS=Sus scro... 362 3e-099
sp|Q7YRC6|AURKB_BOVIN Serine/threonine-protein kinase 12 OS=Bos ... 361 5e-099
sp|O55099|AURKB_RAT Serine/threonine-protein kinase 12 OS=Rattus... 359 2e-098
sp|O14965|STK6_HUMAN Serine/threonine-protein kinase 6 OS=Homo s... 359 3e-098
sp|O70126|AURKB_MOUSE Serine/threonine-protein kinase 12 OS=Mus ... 359 4e-098
sp|Q9UQB9|AURKC_HUMAN Serine/threonine-protein kinase 13 OS=Homo... 351 7e-096
sp|Q54WX4|AURK_DICDI Probable serine/threonine-protein kinase au... 350 2e-095
>sp|Q9M077|AUR1_ARATH Serine/threonine-protein kinase Aurora-1 OS=Arabidopsis
thaliana GN=AUR1 PE=2 SV=1
Length = 294
Score = 561 bits (1445), Expect = 4e-159
Identities = 274/293 (93%), Positives = 284/293 (96%), Gaps = 2/293 (0%)
Frame = -2
Query: 1066 IATETQHHQVEKEASSGASAAAQKRWTLSDFDIGKALGRGKFGHVYLAREKRSNHIVALK 887
I TETQH EKEAS ++AAAQKRWTLSDFDIGK LGRGKFGHVYLAREKRSNH+VALK
Sbjct: 3 IPTETQHQ--EKEASDASAAAAQKRWTLSDFDIGKPLGRGKFGHVYLAREKRSNHVVALK 60
Query: 886 VLFKTQLQESQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKEL 707
VLFK+QLQ+SQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYK+L
Sbjct: 61 VLFKSQLQQSQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKDL 120
Query: 706 QKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTF 527
QKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTF
Sbjct: 121 QKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTF 180
Query: 526 NRRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAVEHSDTYRRIVQ 347
NRRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEA+EHSDTYRRIVQ
Sbjct: 181 NRRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQ 240
Query: 346 VDLKFPPTPIVSPSAKDLISQMLVKESAKRLPLHKLLEHPWIVQNADPSGIYR 188
VDLKFPP PI+S SAKDLISQMLVKES++RLPLHKLLEHPWIVQNADPSGIYR
Sbjct: 241 VDLKFPPKPIISASAKDLISQMLVKESSQRLPLHKLLEHPWIVQNADPSGIYR 293
>sp|Q683C9|AUR2_ARATH Serine/threonine-protein kinase Aurora-2 OS=Arabidopsis
thaliana GN=AUR2 PE=2 SV=2
Length = 282
Score = 536 bits (1379), Expect = 2e-151
Identities = 261/277 (94%), Positives = 267/277 (96%)
Frame = -2
Query: 1015 ASAAAQKRWTLSDFDIGKALGRGKFGHVYLAREKRSNHIVALKVLFKTQLQESQVEHQLR 836
AS AAQKRWT SDFDIGK LGRGKFGHVYLAREKRS+HIVALKVLFK QLQ+SQVEHQLR
Sbjct: 6 ASEAAQKRWTTSDFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQLQQSQVEHQLR 65
Query: 835 REVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKELQKCKYFSERRAATYVAS 656
REVEIQSHLRHPNILRLYGYFYDQKRVYLILEYA RGELYKELQKCKYFSERRAATYVAS
Sbjct: 66 REVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVAS 125
Query: 655 LARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFNRRRTMCGTLDYLPPEM 476
LARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFNRRRTMCGTLDYLPPEM
Sbjct: 126 LARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFNRRRTMCGTLDYLPPEM 185
Query: 475 VESVEHDASVDIWSLGILCYEFLYGVPPFEAVEHSDTYRRIVQVDLKFPPTPIVSPSAKD 296
VESVEHDASVDIWSLGILCYEFLYGVPPFEA EHS+TY+RIVQVDLKFPP PIVS SAKD
Sbjct: 186 VESVEHDASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPIVSSSAKD 245
Query: 295 LISQMLVKESAKRLPLHKLLEHPWIVQNADPSGIYRG 185
LISQMLVKES +RL LHKLLEHPWIVQNADPSG+YRG
Sbjct: 246 LISQMLVKESTQRLALHKLLEHPWIVQNADPSGLYRG 282
>sp|O64629|AUR3_ARATH Serine/threonine-protein kinase Aurora-3 OS=Arabidopsis
thaliana GN=AUR3 PE=2 SV=1
Length = 288
Score = 378 bits (970), Expect = 4e-104
Identities = 173/282 (61%), Positives = 234/282 (82%)
Frame = -2
Query: 1039 VEKEASSGASAAAQKRWTLSDFDIGKALGRGKFGHVYLAREKRSNHIVALKVLFKTQLQE 860
+ K+++ + +K+W+L+DF+IG+ LG+GKFG VYLARE +S +IVALKV+FK Q+++
Sbjct: 1 MSKKSTESDAGNTEKQWSLADFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEK 60
Query: 859 SQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKELQKCKYFSER 680
++ HQLRRE+EIQ+ LRHPNILRL+G+F+D +R++LILEYA GELY L++ + +E+
Sbjct: 61 YKIHHQLRREMEIQTSLRHPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQ 120
Query: 679 RAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFNRRRTMCGT 500
+AATY+ASL++AL YCHGK VIHRDIKPENLL+ +G LKIADFGWSV + N+R+TMCGT
Sbjct: 121 QAATYIASLSQALAYCHGKCVIHRDIKPENLLLDHEGRLKIADFGWSVQSSNKRKTMCGT 180
Query: 499 LDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAVEHSDTYRRIVQVDLKFPPTP 320
LDYL PEMVE+ +HD +VD W+LGILCYEFLYG PPFEA DT++RI+++DL FP TP
Sbjct: 181 LDYLAPEMVENRDHDYAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTP 240
Query: 319 IVSPSAKDLISQMLVKESAKRLPLHKLLEHPWIVQNADPSGI 194
VS AK+LISQ+LVK+ +KRL + K+++HPWIV+NADP G+
Sbjct: 241 NVSEEAKNLISQLLVKDPSKRLSIEKIMQHPWIVKNADPKGV 282
>sp|Q9N0X0|AURKB_PIG Serine/threonine-protein kinase 12 OS=Sus scrofa GN=AURKB
PE=2 SV=2
Length = 344
Score = 372 bits (953), Expect = 4e-102
Identities = 177/271 (65%), Positives = 220/271 (81%), Gaps = 3/271 (1%)
Frame = -2
Query: 1030 EASSGASAAAQKRWTLSDFDIGKALGRGKFGHVYLAREKRSNHIVALKVLFKTQLQESQV 851
E SSG + + +T+ DF+IG+ LG+GKFG+VYLAREK+S+ IVALKVLFK+Q+++ V
Sbjct: 59 ENSSGTPNFSTRSFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGV 118
Query: 850 EHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKELQKCKYFSERRAA 671
EHQLRRE+EIQ+HL+HPNILRLY YFYD++R+YLILEYA RGELYKELQKC+ F E+R A
Sbjct: 119 EHQLRREIEIQAHLQHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKCRTFDEQRTA 178
Query: 670 TYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFN-RRRTMCGTLD 494
T + LA ALIYCHGK VIHRDIKPENLL+G QGELKIADFGWSVH + RR+TMCGTLD
Sbjct: 179 TIMEELADALIYCHGKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLRRKTMCGTLD 238
Query: 493 YLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAVEHSDTYRRIVQVDLKFPPTPIV 314
YLPPEM+E H+ VD+W +G+LCYE L G PPFE+ H++TYRRI +VDLKFPP+ V
Sbjct: 239 YLPPEMIEGRTHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIGKVDLKFPPS--V 296
Query: 313 SPSAKDLISQMLVKESAKRLPLHKLLEHPWI 221
A+DLIS++L + RLPL ++ HPW+
Sbjct: 297 PAGAQDLISKLLKHNPSDRLPLAQVSAHPWV 327
>sp|Q91819|STK6L_XENLA Serine/threonine-protein kinase Eg2-like OS=Xenopus
laevis PE=2 SV=2
Length = 408
Score = 369 bits (946), Expect = 3e-101
Identities = 175/265 (66%), Positives = 214/265 (80%), Gaps = 3/265 (1%)
Frame = -2
Query: 1000 QKRWTLSDFDIGKALGRGKFGHVYLAREKRSNHIVALKVLFKTQLQESQVEHQLRREVEI 821
+K+W L DF+IG+ LG+GKFG+VYLARE+ S I+ALKVLFK+QL+++ VEHQLRREVEI
Sbjct: 132 KKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEI 191
Query: 820 QSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKELQKCKYFSERRAATYVASLARAL 641
QSHLRHPNILRLYGYF+D RVYLIL+YA GEL++ELQKC F ++R+A Y+ LA AL
Sbjct: 192 QSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEAL 251
Query: 640 IYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHT-FNRRRTMCGTLDYLPPEMVESV 464
+YCH K VIHRDIKPENLL+G+ GELKIADFGWSVH +RR T+CGTLDYLPPEM+E
Sbjct: 252 LYCHSKKVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGR 311
Query: 463 EHDASVDIWSLGILCYEFLYGVPPFEAVEHSDTYRRIVQVDLKFPPTPIVSPSAKDLISQ 284
HD VD+WSLG+LCYEFL G PPFE H +TYRRI +V+ ++P P VS AKDL+S+
Sbjct: 312 MHDEKVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYP--PYVSEEAKDLVSK 369
Query: 283 MLVKESAKRLPLHKLLEHPWIVQNA 209
+L RLPL +LEHPWIV+N+
Sbjct: 370 LLKHNPNHRLPLKGVLEHPWIVKNS 394
>sp|Q6GPL3|AUKBB_XENLA Serine/threonine-protein kinase 12-B OS=Xenopus laevis
GN=aurkb-b PE=2 SV=1
Length = 368
Score = 369 bits (945), Expect = 3e-101
Identities = 179/296 (60%), Positives = 231/296 (78%), Gaps = 9/296 (3%)
Frame = -2
Query: 1093 SLSPTSSMAIATETQHHQVEKEASSGASAAAQKRWTLSDFDIGKALGRGKFGHVYLAREK 914
S S +A+ T+ H ++ + A ++++T+ DFDIG+ LG+GKFG+VYLAREK
Sbjct: 67 SSSVPGRVALGTDVASH------NTALAEAPKRKFTIDDFDIGRPLGKGKFGNVYLAREK 120
Query: 913 RSNHIVALKVLFKTQLQESQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYA 734
++ I+ALKVLFK+QL++ VEHQLRRE+EIQSHLRHPNILR+Y YF+D+KR+YL+LE+A
Sbjct: 121 QNKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPNILRMYNYFHDRKRIYLMLEFA 180
Query: 733 ARGELYKELQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIA 554
RGELYKELQK F E+R+AT++ LA AL YCH + VIHRDIKPENLL+G +GELKIA
Sbjct: 181 PRGELYKELQKHGRFDEQRSATFMEELADALQYCHERKVIHRDIKPENLLMGYKGELKIA 240
Query: 553 DFGWSVHTFN-RRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAVE 377
DFGWSVH + RRRTMCGTLDYLPPEM+E HD VD+W G+LCYEFL G+PPF++
Sbjct: 241 DFGWSVHAPSLRRRTMCGTLDYLPPEMIEGKTHDEKVDLWCAGVLCYEFLVGMPPFDSPS 300
Query: 376 HSDTYRRIVQVDLKFPPTPIVSPSAKDLISQMLVKESAKRLPLHKLLEHPWIVQNA 209
HS+T+RRIV VDLKFP P +S +KDLIS++L A+RLPL ++EHPW+ N+
Sbjct: 301 HSETHRRIVNVDLKFP--PFLSEGSKDLISKLLRYHPAQRLPLKGVMEHPWVKANS 354
>sp|Q91820|STK6_XENLA Serine/threonine-protein kinase 6 OS=Xenopus laevis
GN=aurka PE=1 SV=1
Length = 407
Score = 368 bits (943), Expect = 6e-101
Identities = 173/265 (65%), Positives = 215/265 (81%), Gaps = 3/265 (1%)
Frame = -2
Query: 1000 QKRWTLSDFDIGKALGRGKFGHVYLAREKRSNHIVALKVLFKTQLQESQVEHQLRREVEI 821
+K+W L DF+IG+ LG+GKFG+VYLARE+ S I+ALKVLFK+QL+++ VEHQLRREVEI
Sbjct: 132 KKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEI 191
Query: 820 QSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKELQKCKYFSERRAATYVASLARAL 641
QSHLRHPNILRLYGYF+D RVYLIL+YA GEL++ELQKC F ++R+A Y+ LA AL
Sbjct: 192 QSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEAL 251
Query: 640 IYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHT-FNRRRTMCGTLDYLPPEMVESV 464
+YCH K VIHRDIKPENLL+G+ GELKIADFGWSVH +RR T+CGTLDYLPPEM+E
Sbjct: 252 LYCHSKKVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGR 311
Query: 463 EHDASVDIWSLGILCYEFLYGVPPFEAVEHSDTYRRIVQVDLKFPPTPIVSPSAKDLISQ 284
HD +VD+WSLG+LCYEFL G PPFE H +TYRRI +V+ ++P P VS A+DL+S+
Sbjct: 312 MHDETVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYP--PYVSEEARDLVSK 369
Query: 283 MLVKESAKRLPLHKLLEHPWIVQNA 209
+L RLPL +LEHPWI++N+
Sbjct: 370 LLKHNPNHRLPLKGVLEHPWIIKNS 394
>sp|P97477|STK6_MOUSE Serine/threonine-protein kinase 6 OS=Mus musculus GN=Aurka
PE=1 SV=1
Length = 395
Score = 367 bits (942), Expect = 8e-101
Identities = 181/300 (60%), Positives = 225/300 (75%), Gaps = 5/300 (1%)
Frame = -2
Query: 1087 SPTSSMAIATETQHHQVEKEASSGASAAAQKRWTLSDFDIGKALGRGKFGHVYLAREKRS 908
+P + A + E+ + +++WTL DFDIG+ LG+GKFG+VYLARE++S
Sbjct: 87 NPQKNEQPAASGNDSEKEQASLQKTEDTKKRQWTLEDFDIGRPLGKGKFGNVYLARERQS 146
Query: 907 NHIVALKVLFKTQLQESQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAAR 728
I+ALKVLFKTQL+++ VEHQLRREVEIQSHLRHPNILRLYGYF+D RVYLILEYA
Sbjct: 147 KFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPL 206
Query: 727 GELYKELQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADF 548
G +Y+ELQK F E+R ATY+ LA AL YCH K VIHRDIKPENLL+G+ GELKIADF
Sbjct: 207 GTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADF 266
Query: 547 GWSVHT-FNRRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAVEHS 371
GWSVH +RR TMCGTLDYLPPEM+E HD VD+WSLG+LCYEFL G+PPFEA +
Sbjct: 267 GWSVHAPSSRRTTMCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQ 326
Query: 370 DTYRRIVQVDLKFPPTPIVSPSAKDLISQMLVKESAKRLPLHKLLEHPWIVQNAD--PSG 197
+TYRRI +V+ FP V+ A+DLIS++L +++RL L ++LEHPWI N+ P+G
Sbjct: 327 ETYRRISRVEFTFP--DFVTEGARDLISRLLKHNASQRLTLAEVLEHPWIKANSSKPPTG 384
>sp|Q6DE08|AUKBA_XENLA Serine/threonine-protein kinase 12-A OS=Xenopus laevis
GN=aurkb-a PE=1 SV=1
Length = 361
Score = 364 bits (934), Expect = 6e-100
Identities = 178/303 (58%), Positives = 232/303 (76%), Gaps = 9/303 (2%)
Frame = -2
Query: 1114 SNLVLSISLSPTSSMAIATETQHHQVEKEASSGASAAAQKRWTLSDFDIGKALGRGKFGH 935
S + S S S +A++TE ++ + ++++T+ DFDIG+ LG+GKFG+
Sbjct: 53 SRITPSASSSVPGRVAVSTEM------PSQNTALAEMPKRKFTIDDFDIGRPLGKGKFGN 106
Query: 934 VYLAREKRSNHIVALKVLFKTQLQESQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRV 755
VYLAREK++ I+ALKVLFK+QL++ VEHQLRRE+EIQSHLRHPNILR+Y YF+D+KR+
Sbjct: 107 VYLAREKQNKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPNILRMYNYFHDRKRI 166
Query: 754 YLILEYAARGELYKELQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGA 575
YL+LE+A RGELYKELQK F E+R+AT++ LA AL YCH + VIHRDIKPENLL+G
Sbjct: 167 YLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADALHYCHERKVIHRDIKPENLLMGY 226
Query: 574 QGELKIADFGWSVHTFN-RRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGV 398
+GELKIADFGWSVH + RRRTMCGTLDYLPPEM+E HD VD+W G+LCYEFL G+
Sbjct: 227 KGELKIADFGWSVHAPSLRRRTMCGTLDYLPPEMIEGKTHDEKVDLWCAGVLCYEFLVGM 286
Query: 397 PPFEAVEHSDTYRRIVQVDLKFPPTPIVSPSAKDLISQMLVKESAKRLPLHKLLEHPWIV 218
PPF++ H++T+RRIV VDLKFP P +S +KDLIS++L +RLPL ++EHPW+
Sbjct: 287 PPFDSPSHTETHRRIVNVDLKFP--PFLSDGSKDLISKLLRYHPPQRLPLKGVMEHPWVK 344
Query: 217 QNA 209
N+
Sbjct: 345 ANS 347
>sp|P59241|STK6_RAT Serine/threonine-protein kinase 6 OS=Rattus norvegicus
GN=Aurka PE=1 SV=1
Length = 397
Score = 364 bits (933), Expect = 8e-100
Identities = 179/292 (61%), Positives = 222/292 (76%), Gaps = 5/292 (1%)
Frame = -2
Query: 1063 ATETQHHQVEKEASSGASAAAQKRWTLSDFDIGKALGRGKFGHVYLAREKRSNHIVALKV 884
A + + E+ + + +++WTL DFDIG+ LG+GKFG+VYLAREK+S I+ALKV
Sbjct: 97 AASGNNSEKEQTSIQKTEDSKKRQWTLEDFDIGRPLGKGKFGNVYLAREKQSKFILALKV 156
Query: 883 LFKTQLQESQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKELQ 704
LFK QL+++ VEHQLRREVEIQSHLRHPNILRLYGYF+D RVYLILEYA G +Y+ELQ
Sbjct: 157 LFKVQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQ 216
Query: 703 KCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHT-F 527
K F E+R ATY+ LA AL YCH K VIHRDIKPENLL+G+ GELKIADFGWSVH
Sbjct: 217 KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAPS 276
Query: 526 NRRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAVEHSDTYRRIVQ 347
+RR T+CGTLDY PPEM+E HD VD+WSLG+LCYEFL G+PPFEA + +TYRRI +
Sbjct: 277 SRRTTLCGTLDYQPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISR 336
Query: 346 VDLKFPPTPIVSPSAKDLISQMLVKESAKRLPLHKLLEHPWIVQNAD--PSG 197
V+ FP V+ A+DLIS++L S++RL L ++LEHPWI N+ P+G
Sbjct: 337 VEFTFP--DFVTEGARDLISRLLKHNSSQRLTLAEVLEHPWIKANSSKPPTG 386
>sp|Q96GD4|AURKB_HUMAN Serine/threonine-protein kinase 12 OS=Homo sapiens
GN=AURKB PE=1 SV=2
Length = 344
Score = 364 bits (932), Expect = 1e-099
Identities = 175/275 (63%), Positives = 219/275 (79%), Gaps = 3/275 (1%)
Frame = -2
Query: 1030 EASSGASAAAQKRWTLSDFDIGKALGRGKFGHVYLAREKRSNHIVALKVLFKTQLQESQV 851
E SSG + +T+ DF+IG+ LG+GKFG+VYLAREK+S+ IVALKVLFK+Q+++ V
Sbjct: 59 ENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGV 118
Query: 850 EHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKELQKCKYFSERRAA 671
EHQLRRE+EIQ+HL HPNILRLY YFYD++R+YLILEYA RGELYKELQK F E+R A
Sbjct: 119 EHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTA 178
Query: 670 TYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFN-RRRTMCGTLD 494
T + LA AL+YCHGK VIHRDIKPENLL+G +GELKIADFGWSVH + RR+TMCGTLD
Sbjct: 179 TIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLD 238
Query: 493 YLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAVEHSDTYRRIVQVDLKFPPTPIV 314
YLPPEM+E H+ VD+W +G+LCYE L G PPFE+ H++TYRRIV+VDLKFP + V
Sbjct: 239 YLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPAS--V 296
Query: 313 SPSAKDLISQMLVKESAKRLPLHKLLEHPWIVQNA 209
A+DLIS++L ++RLPL ++ HPW+ N+
Sbjct: 297 PTGAQDLISKLLRHNPSERLPLAQVSAHPWVRANS 331
>sp|A4IGM9|AURKB_XENTR Serine/threonine-protein kinase 12 OS=Xenopus tropicalis
GN=aurkb PE=2 SV=1
Length = 360
Score = 363 bits (930), Expect = 2e-099
Identities = 177/298 (59%), Positives = 234/298 (78%), Gaps = 9/298 (3%)
Frame = -2
Query: 1090 LSPTSSMAIATETQHHQVEKEASSGASAAAQ---KRWTLSDFDIGKALGRGKFGHVYLAR 920
++P++S ++ V +ASS +A A+ +++T+ DFDIG+ LG+GKFG+VYLAR
Sbjct: 55 ITPSASSSVPGRV---AVSMDASSQNTALAELPKRKFTIDDFDIGRPLGKGKFGNVYLAR 111
Query: 919 EKRSNHIVALKVLFKTQLQESQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILE 740
+K++ I+ALKVLFK+QL++ VEHQLRRE+EIQSHLRHPNILR+Y YF+D+KR+YL+LE
Sbjct: 112 DKQNKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPNILRMYNYFHDRKRIYLMLE 171
Query: 739 YAARGELYKELQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELK 560
+A RGELYKELQK F E+R+AT++ LA AL YCH + VIHRDIKPENLL+G +GELK
Sbjct: 172 FAPRGELYKELQKHGRFDEQRSATFMEELADALQYCHERKVIHRDIKPENLLMGYKGELK 231
Query: 559 IADFGWSVHTFN-RRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEA 383
IADFGWSVH + RRRTMCGTLDYLPPEM+E HD VD+W G+LC+EFL G+PPF++
Sbjct: 232 IADFGWSVHAPSLRRRTMCGTLDYLPPEMIEGKTHDEKVDLWCAGVLCFEFLVGMPPFDS 291
Query: 382 VEHSDTYRRIVQVDLKFPPTPIVSPSAKDLISQMLVKESAKRLPLHKLLEHPWIVQNA 209
H++T+RRIV VDLKFP P +S +KDLIS++L +RLPL ++EHPW+ N+
Sbjct: 292 PSHTETHRRIVNVDLKFP--PFLSDGSKDLISKLLRYHPPQRLPLKGVMEHPWVKANS 347
>sp|Q2TA06|STK6_BOVIN Serine/threonine-protein kinase 6 OS=Bos taurus GN=AURKA
PE=2 SV=1
Length = 402
Score = 362 bits (929), Expect = 2e-099
Identities = 184/313 (58%), Positives = 227/313 (72%), Gaps = 13/313 (4%)
Frame = -2
Query: 1129 LSSPPSNLVLSISLSPTSSMAIATETQHHQVEKEASSGA--SAAAQKRWTLSDFDIGKAL 956
++ PPSN S P + + EKE +S + +++W L DF+IG+ L
Sbjct: 88 VTRPPSNTQKSKQPQPPA--------PGNNPEKEVASKQKNEESKKRQWALEDFEIGRPL 139
Query: 955 GRGKFGHVYLAREKRSNHIVALKVLFKTQLQESQVEHQLRREVEIQSHLRHPNILRLYGY 776
G+GKFG+VYLAREK+S I+ALKVLFK QL+++ VEHQLRREVEIQSHLRHPNILRLYGY
Sbjct: 140 GKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGY 199
Query: 775 FYDQKRVYLILEYAARGELYKELQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKP 596
F+D RVYLILEYA G +Y+ELQK F E+R ATY+ LA AL YCH K VIHRDIKP
Sbjct: 200 FHDATRVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
Query: 595 ENLLIGAQGELKIADFGWSVHT-FNRRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILC 419
ENLL+G+ GELKIADFGWSVH +RR T+CGTLDYLPPEM+E HD VD+WSLG+LC
Sbjct: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLC 319
Query: 418 YEFLYGVPPFEAVEHSDTYRRIVQVDLKFPPTPIVSPSAKDLISQMLVKESAKRLPLHKL 239
YEFL G PPFEA + +TYRRI +V+ FP V A+DLIS++L ++R L ++
Sbjct: 320 YEFLVGKPPFEADTYQETYRRISRVEFTFP--DCVPEGARDLISRLLKHNPSQRPTLKEV 377
Query: 238 LEHPWIVQNADPS 200
LEHPWI+ N+ PS
Sbjct: 378 LEHPWIIANSKPS 390
>sp|A5GFW1|STK6_PIG Serine/threonine-protein kinase 6 OS=Sus scrofa GN=AURKA
PE=3 SV=1
Length = 402
Score = 362 bits (928), Expect = 3e-099
Identities = 178/286 (62%), Positives = 219/286 (76%), Gaps = 5/286 (1%)
Frame = -2
Query: 1036 EKEASSGA--SAAAQKRWTLSDFDIGKALGRGKFGHVYLAREKRSNHIVALKVLFKTQLQ 863
EKEA+S + +++W L DF+IG+ LG+GKFG+VYLAREK+S I+ALKVLFKTQL+
Sbjct: 111 EKEAASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKTQLE 170
Query: 862 ESQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKELQKCKYFSE 683
++ VEHQLRREVEIQSHLRHPNILRLYGYF+D RVYLILEYA G +Y+ELQK F E
Sbjct: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGAVYRELQKLSKFDE 230
Query: 682 RRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHT-FNRRRTMC 506
+R ATY+ LA AL YCH K VIHRDIKPENLL+G+ GELKIADFGWSVH +RR T+C
Sbjct: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC 290
Query: 505 GTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAVEHSDTYRRIVQVDLKFPP 326
GTLDYLPPEM+E HD VD+WSLG+LCYEFL G PPFEA + +TY+RI +V+ FP
Sbjct: 291 GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFP- 349
Query: 325 TPIVSPSAKDLISQMLVKESAKRLPLHKLLEHPWIVQNADPSGIYR 188
V A+DLIS++L + R L ++LEHPWI N+ P+ ++
Sbjct: 350 -DFVPEGARDLISRLLKHNPSHRPTLKEVLEHPWITANSKPASSHK 394
>sp|Q7YRC6|AURKB_BOVIN Serine/threonine-protein kinase 12 OS=Bos taurus GN=AURKB
PE=2 SV=1
Length = 344
Score = 361 bits (926), Expect = 5e-099
Identities = 172/271 (63%), Positives = 217/271 (80%), Gaps = 3/271 (1%)
Frame = -2
Query: 1030 EASSGASAAAQKRWTLSDFDIGKALGRGKFGHVYLAREKRSNHIVALKVLFKTQLQESQV 851
E SSG ++ +T+ DF+IG+ LG+GKFG+VYLAREK+S+ IVALKVLFK+Q+++ V
Sbjct: 59 ENSSGTPNIPKRSFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGV 118
Query: 850 EHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKELQKCKYFSERRAA 671
EHQLRRE+EIQ+HL+HPNILRLY YFYD++R+YLILEYA RGELYKELQK + F E+R A
Sbjct: 119 EHQLRREIEIQAHLQHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSRTFDEQRTA 178
Query: 670 TYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFN-RRRTMCGTLD 494
T + LA AL YCH K VIHRDIKPENLL+G +GELKIADFGWSVH + RR+TMCGTLD
Sbjct: 179 TIMEELADALTYCHAKKVIHRDIKPENLLLGLRGELKIADFGWSVHAPSLRRKTMCGTLD 238
Query: 493 YLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAVEHSDTYRRIVQVDLKFPPTPIV 314
YLPPEM+E H+ VD+W +G+LCYE L G PPFE+ H++TYRRIV+VDLKFPP+ V
Sbjct: 239 YLPPEMIEGRTHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPPS--V 296
Query: 313 SPSAKDLISQMLVKESAKRLPLHKLLEHPWI 221
A+D I ++L ++RLPL ++ HPW+
Sbjct: 297 PLGAQDFIYKLLKHNPSERLPLAQVSAHPWV 327
>sp|O55099|AURKB_RAT Serine/threonine-protein kinase 12 OS=Rattus norvegicus
GN=Aurkb PE=1 SV=1
Length = 343
Score = 359 bits (921), Expect = 2e-098
Identities = 175/309 (56%), Positives = 233/309 (75%), Gaps = 3/309 (0%)
Frame = -2
Query: 1132 ILSSPPSNLVLSISLSPTSSMAIATETQHHQVEKEASSGASAAAQKRWTLSDFDIGKALG 953
+L P+ ++ ++S + A Q K A++ + +++ +T+ +F+IG+ LG
Sbjct: 28 VLRKEPAVTPAQALMNRSNSQSTAVPGQKLTENKGATALQGSQSRQPFTIDNFEIGRPLG 87
Query: 952 RGKFGHVYLAREKRSNHIVALKVLFKTQLQESQVEHQLRREVEIQSHLRHPNILRLYGYF 773
+GKFG+VYLAREK+S IVALK+LFK+Q+++ VEHQLRRE+EIQ+HL+HPNIL+LY YF
Sbjct: 88 KGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYF 147
Query: 772 YDQKRVYLILEYAARGELYKELQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPE 593
YDQ+R+YLILEYA RGELYKELQK F E+R AT + L+ AL+YCH K VIHRDIKPE
Sbjct: 148 YDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEELSDALMYCHKKKVIHRDIKPE 207
Query: 592 NLLIGAQGELKIADFGWSVHTFN-RRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCY 416
NLL+G QGELKIADFGWSVH + RR+TMCGTLDYLPPEM+E H+ VD+W +G+LCY
Sbjct: 208 NLLLGLQGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLCY 267
Query: 415 EFLYGVPPFEAVEHSDTYRRIVQVDLKFPPTPIVSPSAKDLISQMLVKESAKRLPLHKLL 236
E + G PPFE+ HS+TYRRIV+VDLKFP + + AKDLIS++L ++RLPL ++
Sbjct: 268 ELMVGNPPFESPSHSETYRRIVKVDLKFPSS--MPLGAKDLISKLLKHNPSQRLPLEQVS 325
Query: 235 EHPWIVQNA 209
HPW+ N+
Sbjct: 326 AHPWVRANS 334
>sp|O14965|STK6_HUMAN Serine/threonine-protein kinase 6 OS=Homo sapiens GN=AURKA
PE=1 SV=2
Length = 403
Score = 359 bits (920), Expect = 3e-098
Identities = 179/308 (58%), Positives = 228/308 (74%), Gaps = 4/308 (1%)
Frame = -2
Query: 1126 SSPPSNLVLSISLSPTSSMAIATETQHHQVEKEASSGASAAAQKR-WTLSDFDIGKALGR 950
+S P + ++ + S + + +++ E+ AS + ++KR W L DF+IG+ LG+
Sbjct: 82 TSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGK 141
Query: 949 GKFGHVYLAREKRSNHIVALKVLFKTQLQESQVEHQLRREVEIQSHLRHPNILRLYGYFY 770
GKFG+VYLAREK+S I+ALKVLFK QL+++ VEHQLRREVEIQSHLRHPNILRLYGYF+
Sbjct: 142 GKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFH 201
Query: 769 DQKRVYLILEYAARGELYKELQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPEN 590
D RVYLILEYA G +Y+ELQK F E+R ATY+ LA AL YCH K VIHRDIKPEN
Sbjct: 202 DATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPEN 261
Query: 589 LLIGAQGELKIADFGWSVHT-FNRRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYE 413
LL+G+ GELKIADFGWSVH +RR T+CGTLDYLPPEM+E HD VD+WSLG+LCYE
Sbjct: 262 LLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYE 321
Query: 412 FLYGVPPFEAVEHSDTYRRIVQVDLKFPPTPIVSPSAKDLISQMLVKESAKRLPLHKLLE 233
FL G PPFEA + +TY+RI +V+ FP V+ A+DLIS++L ++R L ++LE
Sbjct: 322 FLVGKPPFEANTYQETYKRISRVEFTFP--DFVTEGARDLISRLLKHNPSQRPMLREVLE 379
Query: 232 HPWIVQNA 209
HPWI N+
Sbjct: 380 HPWITANS 387
>sp|O70126|AURKB_MOUSE Serine/threonine-protein kinase 12 OS=Mus musculus
GN=Aurkb PE=1 SV=1
Length = 345
Score = 359 bits (919), Expect = 4e-098
Identities = 178/310 (57%), Positives = 230/310 (74%), Gaps = 5/310 (1%)
Frame = -2
Query: 1129 LSSPPSNLVLSISLSPTSSMAIATETQHHQVEKEASSGASAAAQKR--WTLSDFDIGKAL 956
L P+ ++ ++S + A Q K S AS +Q + +T+ +F+IG+ L
Sbjct: 29 LRKEPATTSALALVNRSNSQSTAAPGQKLAENKSQGSTASQGSQNKQPFTIDNFEIGRPL 88
Query: 955 GRGKFGHVYLAREKRSNHIVALKVLFKTQLQESQVEHQLRREVEIQSHLRHPNILRLYGY 776
G+GKFG+VYLAREK+S IVALK+LFK+Q+++ VEHQLRRE+EIQ+HL+HPNIL+LY Y
Sbjct: 89 GKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNY 148
Query: 775 FYDQKRVYLILEYAARGELYKELQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKP 596
FYDQ+R+YLILEYA RGELYKELQK + F E+R AT + L+ AL YCH K VIHRDIKP
Sbjct: 149 FYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELSDALTYCHKKKVIHRDIKP 208
Query: 595 ENLLIGAQGELKIADFGWSVHTFN-RRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILC 419
ENLL+G QGELKIADFGWSVH + RR+TMCGTLDYLPPEM+E H+ VD+W +G+LC
Sbjct: 209 ENLLLGLQGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLC 268
Query: 418 YEFLYGVPPFEAVEHSDTYRRIVQVDLKFPPTPIVSPSAKDLISQMLVKESAKRLPLHKL 239
YE + G PPFE+ HS+TYRRIV+VDLKFP + V A+DLIS++L +RLPL ++
Sbjct: 269 YELMVGNPPFESPSHSETYRRIVKVDLKFPSS--VPSGAQDLISKLLKHNPWQRLPLAEV 326
Query: 238 LEHPWIVQNA 209
HPW+ N+
Sbjct: 327 AAHPWVRANS 336
>sp|Q9UQB9|AURKC_HUMAN Serine/threonine-protein kinase 13 OS=Homo sapiens
GN=AURKC PE=2 SV=1
Length = 309
Score = 351 bits (899), Expect = 7e-096
Identities = 167/265 (63%), Positives = 215/265 (81%), Gaps = 3/265 (1%)
Frame = -2
Query: 1012 SAAAQKRWTLSDFDIGKALGRGKFGHVYLAREKRSNHIVALKVLFKTQLQESQVEHQLRR 833
S+ A +R T+ DF+IG+ LG+GKFG+VYLAR K S+ IVALKVLFK+Q+++ +EHQLRR
Sbjct: 31 SSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRR 90
Query: 832 EVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKELQKCKYFSERRAATYVASL 653
E+EIQ+HL+HPNILRLY YF+D +RVYLILEYA RGELYKELQK + E+R AT + L
Sbjct: 91 EIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEL 150
Query: 652 ARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFN-RRRTMCGTLDYLPPEM 476
A AL YCH K VIHRDIKPENLL+G +GE+KIADFGWSVHT + RR+TMCGTLDYLPPEM
Sbjct: 151 ADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEM 210
Query: 475 VESVEHDASVDIWSLGILCYEFLYGVPPFEAVEHSDTYRRIVQVDLKFPPTPIVSPSAKD 296
+E +D VD+W +G+LCYE L G PPFE+ HS+TYRRI++VD++FP + + A+D
Sbjct: 211 IEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLS--MPLGARD 268
Query: 295 LISQMLVKESAKRLPLHKLLEHPWI 221
LIS++L + +RLPL ++L+HPW+
Sbjct: 269 LISRLLRYQPLERLPLAQILKHPWV 293
>sp|Q54WX4|AURK_DICDI Probable serine/threonine-protein kinase aurK
OS=Dictyostelium discoideum GN=aurK PE=1 SV=1
Length = 384
Score = 350 bits (896), Expect = 2e-095
Identities = 172/310 (55%), Positives = 223/310 (71%), Gaps = 8/310 (2%)
Frame = -2
Query: 1120 PPSNLVLSISLSPTSSMAIATETQHHQVEKEASSGASAAAQKRWTLSDFDIGKALGRGKF 941
PP+ S S S +SS + ++ + +SS + + +K+W + DFDIGK LG G+F
Sbjct: 67 PPTTTASSSSSSSSSSSSSSSSS-----SSSSSSSSQSVPKKKWCIDDFDIGKLLGMGRF 121
Query: 940 GHVYLAREKRSNHIVALKVLFKTQLQESQVEHQLRREVEIQSHLRHPNILRLYGYFYDQK 761
GHVYLAREK+S IVALKVLFK QLQ +EHQLRRE+EIQSHLRHPNILRL+GYFYD K
Sbjct: 122 GHVYLAREKKSQFIVALKVLFKNQLQTHNIEHQLRREIEIQSHLRHPNILRLFGYFYDDK 181
Query: 760 RVYLILEYAARGELYKELQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLI 581
RV+LI+E+A GE +KELQK F+E+ AATY +A AL YCH KHVIHRDIKPENLLI
Sbjct: 182 RVFLIIEFAKGGECFKELQKVGSFNEQTAATYTLQIADALRYCHSKHVIHRDIKPENLLI 241
Query: 580 GAQGELKIADFGWSVHTFN-RRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLY 404
G GE+KIADFGWSVH N +R T CGTL+YLPPE++E +D + D+WSLGIL +EFL
Sbjct: 242 GVGGEIKIADFGWSVHAPNTKRSTFCGTLEYLPPEVIEKKGYDQTADVWSLGILIFEFLV 301
Query: 403 GVPPFEAVEHSDTYRRIVQVDLKFPPTPIVSPSAKDLISQMLVKESAKRLPLHKLLEHPW 224
G PF + E + + I + D+ +P + +SP AKDLIS++LV + +R+ L ++ HPW
Sbjct: 302 GRSPFTSDEEKNIFHNIQENDVYYPSS--ISPEAKDLISRLLVSDPHQRITLKDVINHPW 359
Query: 223 IVQNADPSGI 194
I ++A P +
Sbjct: 360 IKKHAHPKSL 369
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,759,707,213
Number of Sequences: 518415
Number of Extensions: 54759707213
Number of Successful Extensions: 366332288
Number of sequences better than 0.0: 0
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