BLASTX 7.6.2
Query= UN13756 /QuerySize=3198
(3197 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O50008|METE_ARATH 5-methyltetrahydropteroyltriglutamate--homo... 1130 0.0
sp|P93263|METE_MESCR 5-methyltetrahydropteroyltriglutamate--homo... 1031 4e-300
sp|Q42699|METE_CATRO 5-methyltetrahydropteroyltriglutamate--homo... 1025 2e-298
sp|Q42662|METE_SOLSC 5-methyltetrahydropteroyltriglutamate--homo... 1013 2e-294
sp|B4EJ37|METE_BURCJ 5-methyltetrahydropteroyltriglutamate--homo... 606 6e-172
sp|B1K5S8|METE_BURCC 5-methyltetrahydropteroyltriglutamate--homo... 604 2e-171
sp|Q39AN3|METE_BURS3 5-methyltetrahydropteroyltriglutamate--homo... 603 4e-171
sp|B1Z0R8|METE_BURA4 5-methyltetrahydropteroyltriglutamate--homo... 602 6e-171
sp|Q1BQX8|METE_BURCA 5-methyltetrahydropteroyltriglutamate--homo... 601 1e-170
sp|A0B2Z3|METE_BURCH 5-methyltetrahydropteroyltriglutamate--homo... 601 1e-170
sp|Q0B6M7|METE_BURCM 5-methyltetrahydropteroyltriglutamate--homo... 597 2e-169
sp|A4JJS1|METE_BURVG 5-methyltetrahydropteroyltriglutamate--homo... 592 7e-168
sp|Q8XS05|METE_RALSO 5-methyltetrahydropteroyltriglutamate--homo... 583 3e-165
sp|A1TYT7|METE_MARAV 5-methyltetrahydropteroyltriglutamate--homo... 579 6e-164
sp|Q1QZS5|METE_CHRSD 5-methyltetrahydropteroyltriglutamate--homo... 576 5e-163
sp|B2JNZ4|METE_BURP8 5-methyltetrahydropteroyltriglutamate--homo... 575 6e-163
sp|B2UJ81|METE_RALPJ 5-methyltetrahydropteroyltriglutamate--homo... 568 1e-160
sp|Q9JUT6|METE_NEIMA 5-methyltetrahydropteroyltriglutamate--homo... 565 9e-160
sp|Q9JZQ2|METE_NEIMB 5-methyltetrahydropteroyltriglutamate--homo... 564 1e-159
sp|A5FJR8|METE_FLAJ1 5-methyltetrahydropteroyltriglutamate--homo... 564 2e-159
>sp|O50008|METE_ARATH 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Arabidopsis thaliana GN=CIMS PE=1 SV=1
Length = 765
Score = 1130 bits (2921), Expect = 0.0
Identities = 570/579 (98%), Positives = 577/579 (99%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
+Y+EVITELKAAGATWIQLDEPVLVMDLEG KLQAFTGAYAELESTLSGLNVLVETYFAD
Sbjct: 187 IYKEVITELKAAGATWIQLDEPVLVMDLEGQKLQAFTGAYAELESTLSGLNVLVETYFAD 246
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
IPAEAYKTLTSLKGVTA+GFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS
Sbjct: 247 IPAEAYKTLTSLKGVTAFGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 306
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
LSTL+ALEG+VGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSW+AFAAQKVVEVNALAK
Sbjct: 307 LSTLQALEGIVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWLAFAAQKVVEVNALAK 366
Query: 1772 ALAGHKDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQKK 1951
ALAG KDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQKK
Sbjct: 367 ALAGQKDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQKK 426
Query: 1952 LNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDIDVL 2131
LNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKA+KEEIKKVVDLQEELDIDVL
Sbjct: 427 LNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAIKEEIKKVVDLQEELDIDVL 486
Query: 2132 VHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSAMA 2311
VHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSAMA
Sbjct: 487 VHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSAMA 546
Query: 2312 QSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQIDE 2491
QSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQIDE
Sbjct: 547 QSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQIDE 606
Query: 2492 AALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMDAD 2671
AALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMDAD
Sbjct: 607 AALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMDAD 666
Query: 2672 VITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQNI 2851
VITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQNI
Sbjct: 667 VITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQNI 726
Query: 2852 LWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASAK 2968
LWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASAK
Sbjct: 727 LWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASAK 765
>sp|P93263|METE_MESCR 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Mesembryanthemum crystallinum GN=METE PE=2 SV=1
Length = 765
Score = 1031 bits (2665), Expect = 4e-300
Identities = 513/579 (88%), Positives = 544/579 (93%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
+Y+EV+ ELK AGA+WIQ DEP+LVMDLE HKLQAF+ AYA+LESTLSGLNV+VETYFAD
Sbjct: 187 IYKEVVAELKEAGASWIQFDEPLLVMDLESHKLQAFSAAYADLESTLSGLNVVVETYFAD 246
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ AEAYKTL SLKGVT YGFDLVRGTKTLDLVKA FP GKYLFAGVVDGRNIWAND AAS
Sbjct: 247 VTAEAYKTLISLKGVTGYGFDLVRGTKTLDLVKAEFPSGKYLFAGVVDGRNIWANDLAAS 306
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
L+TLEALEGVVGKDKLVVSTSCS LHTAVDLINETKLDDEIKSW+AFAAQKV+EVNALAK
Sbjct: 307 LATLEALEGVVGKDKLVVSTSCSFLHTAVDLINETKLDDEIKSWLAFAAQKVLEVNALAK 366
Query: 1772 ALAGHKDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQKK 1951
AL+G KDEA FSANAAALASR+SSPRVTNE VQKAA ALKGSDHRRAT VS+RLDAQQKK
Sbjct: 367 ALSGQKDEAFFSANAAALASRKSSPRVTNEAVQKAATALKGSDHRRATTVSSRLDAQQKK 426
Query: 1952 LNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDIDVL 2131
LNLPILPTTTIGSFPQTVELRRVRREYKAKK+SEE+YVKA+KEEI KVV LQEELDIDVL
Sbjct: 427 LNLPILPTTTIGSFPQTVELRRVRREYKAKKISEEEYVKAIKEEISKVVKLQEELDIDVL 486
Query: 2132 VHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSAMA 2311
VHGEPERNDMVEYFGEQLSGFAF+ANGWVQSYGSRCVKPP+IYGDVSRP MTVFWS+MA
Sbjct: 487 VHGEPERNDMVEYFGEQLSGFAFSANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWSSMA 546
Query: 2312 QSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQIDE 2491
QSMT+RPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIK+EVEDLEK GI VIQIDE
Sbjct: 547 QSMTARPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKNEVEDLEKAGINVIQIDE 606
Query: 2492 AALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMDAD 2671
AALREGLPLRKSEH FYL WAVHSFRITN GVQD+TQIHTHMCYS+FNDIIHSIIDMDAD
Sbjct: 607 AALREGLPLRKSEHDFYLKWAVHSFRITNVGVQDTTQIHTHMCYSNFNDIIHSIIDMDAD 666
Query: 2672 VITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQNI 2851
VITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIP +EE+ADR+ KMLAVLE N+
Sbjct: 667 VITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPPTEELADRIRKMLAVLESNV 726
Query: 2852 LWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASAK 2968
LWVNPDCGLKTRKY EV PAL NMV AAK +R +LASAK
Sbjct: 727 LWVNPDCGLKTRKYGEVNPALSNMVAAAKQLRQELASAK 765
>sp|Q42699|METE_CATRO 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Catharanthus roseus GN=METE PE=2 SV=1
Length = 765
Score = 1025 bits (2650), Expect = 2e-298
Identities = 509/579 (87%), Positives = 543/579 (93%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY+EVI ELKAAGA+WIQ DEP LV+DLE H+L+AFT AY+ELESTLSGLNV+VETYFAD
Sbjct: 187 VYKEVIGELKAAGASWIQFDEPTLVLDLESHQLEAFTKAYSELESTLSGLNVIVETYFAD 246
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
IPAE YK LT+LKGVT +GFDLVRG KTLDL+K GFP GKYLFAGVVDGRNIWAND AAS
Sbjct: 247 IPAETYKILTALKGVTGFGFDLVRGAKTLDLIKGGFPSGKYLFAGVVDGRNIWANDLAAS 306
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
LSTL++LEG+VGKDKLVVSTSCSLLHTAVDL+NE KLD EIKSW+AFAAQKVVEVNALAK
Sbjct: 307 LSTLQSLEGIVGKDKLVVSTSCSLLHTAVDLVNEPKLDKEIKSWLAFAAQKVVEVNALAK 366
Query: 1772 ALAGHKDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQKK 1951
ALAG KDEA FS NAAA ASR+SSPRVTN+ VQKAAAAL+GSDHRRAT VSARLDAQQKK
Sbjct: 367 ALAGEKDEAFFSENAAAQASRKSSPRVTNQAVQKAAAALRGSDHRRATTVSARLDAQQKK 426
Query: 1952 LNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDIDVL 2131
LNLP+LPTTTIGSFPQT+ELRRVRREYKAKK+SE+DYVKA+KEEI KVV LQEELDIDVL
Sbjct: 427 LNLPVLPTTTIGSFPQTLELRRVRREYKAKKISEDDYVKAIKEEISKVVKLQEELDIDVL 486
Query: 2132 VHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSAMA 2311
VHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPP+IYGDVSRP MTVFWS A
Sbjct: 487 VHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWSQTA 546
Query: 2312 QSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQIDE 2491
QSMT RPMKGMLTGPVTILNWSFVRNDQPR ETCYQIALAIKDEVEDLEK GI VIQIDE
Sbjct: 547 QSMTKRPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKDEVEDLEKAGINVIQIDE 606
Query: 2492 AALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMDAD 2671
AALREGLPLRK+EHAFYLDWAVHSFRITN +QD+TQIHTHMCYS+FNDIIHSIIDMDAD
Sbjct: 607 AALREGLPLRKAEHAFYLDWAVHSFRITNLPLQDTTQIHTHMCYSNFNDIIHSIIDMDAD 666
Query: 2672 VITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQNI 2851
V+TIENSRS EKLLSVFREGVKYGAGIGPGVYDIHSPRIPS+EEIADR+NKMLAVL+ NI
Sbjct: 667 VMTIENSRSSEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSTEEIADRINKMLAVLDTNI 726
Query: 2852 LWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASAK 2968
LWVNPDCGLKTRKY EVKPAL+NMV AAKLIR+QLASAK
Sbjct: 727 LWVNPDCGLKTRKYAEVKPALENMVSAAKLIRTQLASAK 765
>sp|Q42662|METE_SOLSC 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Solenostemon scutellarioides GN=MET PE=1 SV=2
Length = 764
Score = 1013 bits (2617), Expect = 2e-294
Identities = 499/579 (86%), Positives = 540/579 (93%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
+Y+EVI ELKAAGA+WIQ DEP LV+DLE H+L AFT AYAELES+LSGL+ L+ETYFAD
Sbjct: 186 IYKEVIAELKAAGASWIQFDEPTLVLDLESHQLDAFTKAYAELESSLSGLSTLIETYFAD 245
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+PA AYKTLTSL G++ +GFDLVRG +T++L+K GFP GKYLFAGVVDGRNIWAND A+S
Sbjct: 246 VPAPAYKTLTSLSGISGFGFDLVRGAQTIELIKGGFPSGKYLFAGVVDGRNIWANDLASS 305
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
++TL+ALEG+VGKDKLVVSTS SLLHTAVDL+NE KLD EIKSW+AFAAQK+VEVNALAK
Sbjct: 306 ITTLQALEGIVGKDKLVVSTSSSLLHTAVDLVNEPKLDQEIKSWLAFAAQKIVEVNALAK 365
Query: 1772 ALAGHKDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQKK 1951
AL GHKDEA FS NAAA ASR+SSPRV NE VQKAAAAL+GS+HRR TNVSARLDAQQKK
Sbjct: 366 ALTGHKDEAFFSPNAAAQASRKSSPRVNNEAVQKAAAALRGSEHRRVTNVSARLDAQQKK 425
Query: 1952 LNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDIDVL 2131
LNLPILPTTTIGSFPQTVELRRVRRE+K ++SEE+YVKA+KEEI KVV LQEELDIDVL
Sbjct: 426 LNLPILPTTTIGSFPQTVELRRVRREFKPTRISEEEYVKAIKEEINKVVKLQEELDIDVL 485
Query: 2132 VHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSAMA 2311
VHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPP+IYGDVSRPK MTVFWS A
Sbjct: 486 VHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPIIYGDVSRPKPMTVFWSTAA 545
Query: 2312 QSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQIDE 2491
QSMT RPMKGMLTGPVTILNWSFVRNDQPR ETCYQIALAIKDEVEDLEK GI VIQIDE
Sbjct: 546 QSMTQRPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKDEVEDLEKAGITVIQIDE 605
Query: 2492 AALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMDAD 2671
AALREGLPLRKSEHAFYLDWAVHSFRITN GVQD+TQIHTHMCYS+FNDIIHSII+MDAD
Sbjct: 606 AALREGLPLRKSEHAFYLDWAVHSFRITNVGVQDTTQIHTHMCYSNFNDIIHSIINMDAD 665
Query: 2672 VITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQNI 2851
VITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPS+EEIADR+NKMLAVLE NI
Sbjct: 666 VITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSTEEIADRINKMLAVLETNI 725
Query: 2852 LWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASAK 2968
LWVNPDCGLKTRKY EVKPAL+NMV AAKL+R+QLASAK
Sbjct: 726 LWVNPDCGLKTRKYAEVKPALENMVAAAKLLRTQLASAK 764
>sp|B4EJ37|METE_BURCJ 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Burkholderia cepacia (strain J2315 / LMG 16656)
GN=metE PE=3 SV=1
Length = 764
Score = 606 bits (1560), Expect = 6e-172
Identities = 322/577 (55%), Positives = 398/577 (68%), Gaps = 8/577 (1%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY ++ L A G W+Q+DEP+LV +L+ QAF AYA LE+ +N+L+ TYF
Sbjct: 193 VYGALLDTLTAQGVEWVQIDEPILVTELDAEWRQAFRTAYAALET--RRINLLLATYFGQ 250
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ + TL + V D + +D + P + L G ++GRNIW D A+
Sbjct: 251 L--QDNLTLAASLPVDGLHIDAINARDEVDALVRELPPERVLSIGAINGRNIWKTDLNAT 308
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
L LE L +G D+L ++ SCSLLH VDL NE KLD EI+SW+AFA QK+ E+ LA
Sbjct: 309 LDWLEPLAKQLG-DRLWLAPSCSLLHVPVDLANEAKLDAEIRSWLAFALQKLDELKVLAT 367
Query: 1772 ALAGHKDEA--LFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQ 1945
AL +D +ANAAA+ SRR SPRV N V+ A A + RA+ + R Q
Sbjct: 368 ALNEGRDTVADALAANAAAIESRRRSPRVNNPAVKAAIARIDARLGNRASPYAQRASKQS 427
Query: 1946 KKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDID 2125
+LNLP PTTTIGSFPQT E+R+ R +KA + E Y AM+ EI++ V QE L++D
Sbjct: 428 ARLNLPAFPTTTIGSFPQTAEIRQARSRFKAGTLDEAGYRTAMQAEIERSVREQESLELD 487
Query: 2126 VLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSA 2305
VLVHGE ERNDMVEYFGEQL G+AF+ GWVQSYGSRCVKPP+++GD+SRPKAMTV W
Sbjct: 488 VLVHGEAERNDMVEYFGEQLDGYAFSQFGWVQSYGSRCVKPPILFGDISRPKAMTVEWIT 547
Query: 2306 MAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQI 2485
AQS+T++PMKGMLTGPVTILNWSFVR+DQPR +CYQ+ALAI+DEV DLE+ G+ VIQI
Sbjct: 548 YAQSLTNKPMKGMLTGPVTILNWSFVRDDQPRSVSCYQLALAIRDEVLDLEQAGVRVIQI 607
Query: 2486 DEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMD 2665
DEAALREGLPLR+++ + YL WAV SFRIT GVQD TQIHTHMCYS FNDII SI DMD
Sbjct: 608 DEAALREGLPLRRAQWSEYLKWAVESFRITANGVQDDTQIHTHMCYSEFNDIIASIADMD 667
Query: 2666 ADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQ 2845
ADVITIE SRSD +LL F + KY IGPGVYDIHSP IP+ + I + K +
Sbjct: 668 ADVITIETSRSDMELLDAF-DDFKYPNEIGPGVYDIHSPNIPTQDHIVGLMRKAAERIPA 726
Query: 2846 NILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQL 2956
LWVNPDCGLKTR++ EV PAL NMV AAK +R+Q+
Sbjct: 727 ERLWVNPDCGLKTRQWGEVIPALTNMVAAAKTLRNQV 763
>sp|B1K5S8|METE_BURCC 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Burkholderia cenocepacia (strain MC0-3) GN=metE
PE=3 SV=1
Length = 764
Score = 604 bits (1555), Expect = 2e-171
Identities = 321/577 (55%), Positives = 399/577 (69%), Gaps = 8/577 (1%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY ++ L A G W+Q+DEP+LV +L+ QAF AYA LE+ + +L+ TYF
Sbjct: 193 VYGALLDTLTAQGVEWVQIDEPILVTELDAEWRQAFRIAYAALET--RRIKLLLATYFGQ 250
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ + TL + V D + +D + P + L G ++GRNIW D A+
Sbjct: 251 L--QDNLTLAASLPVDGLHIDAINARDEVDALVRELPAERVLSVGAINGRNIWKTDLNAA 308
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
L LE L +G D+L ++ SCSLLH VDL +E KLD EI+SW+AFA QK+ E+ LA
Sbjct: 309 LDWLEPLAKQLG-DRLWLAPSCSLLHVPVDLASEEKLDAEIRSWLAFALQKLDELKVLAT 367
Query: 1772 ALAGHKDEA--LFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQ 1945
AL +D+ +ANAAA+ SRR SPRV N V+ A A + R + + R Q
Sbjct: 368 ALNEGRDKVADALAANAAAIDSRRRSPRVNNPAVKAAIARIDARLGNRTSPYTQRASKQS 427
Query: 1946 KKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDID 2125
+LNLP PTTTIGSFPQT E+R+ R +KA + E Y KAM+ EI++ V QE L++D
Sbjct: 428 ARLNLPAFPTTTIGSFPQTAEIRQARSRFKAGALDEAGYRKAMQAEIERSVREQESLELD 487
Query: 2126 VLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSA 2305
VLVHGE ERNDMVEYFGEQL G+AF+ GWVQSYGSRCVKPP+++GD+SRPKAMTV W A
Sbjct: 488 VLVHGEAERNDMVEYFGEQLDGYAFSQFGWVQSYGSRCVKPPILFGDISRPKAMTVEWIA 547
Query: 2306 MAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQI 2485
AQS+T +PMKGMLTGPVTILNWSFVR+DQPR +CYQ+ALAI++EV DLEK G+ VIQI
Sbjct: 548 YAQSLTRKPMKGMLTGPVTILNWSFVRDDQPRAVSCYQLALAIREEVLDLEKAGVRVIQI 607
Query: 2486 DEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMD 2665
DEAALREGLPLR+++ + YL WAV SFRIT GVQD TQIHTHMCYS FNDII SI DMD
Sbjct: 608 DEAALREGLPLRRAQWSEYLKWAVESFRITANGVQDDTQIHTHMCYSEFNDIIASIADMD 667
Query: 2666 ADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQ 2845
ADVITIE SRSD +LL F + KY IGPGVYDIHSP IP+ + I + K +
Sbjct: 668 ADVITIETSRSDMELLDAF-DTFKYPNEIGPGVYDIHSPNIPTQDHIVGLMRKAAERIPA 726
Query: 2846 NILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQL 2956
LWVNPDCGLKTR++ EV PAL NMV AAK++R+Q+
Sbjct: 727 ERLWVNPDCGLKTRQWAEVIPALTNMVAAAKMLRNQV 763
>sp|Q39AN3|METE_BURS3 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Burkholderia sp. (strain 383) GN=metE PE=3 SV=1
Length = 764
Score = 603 bits (1553), Expect = 4e-171
Identities = 321/577 (55%), Positives = 397/577 (68%), Gaps = 8/577 (1%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY ++ L A G W+Q+DEP+LV +L+ QAF AYA LE+ + VL+ TYF
Sbjct: 193 VYGALLDTLTAQGVEWVQIDEPILVTELDAAWQQAFRTAYAALET--RRIKVLLATYFGQ 250
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ + L + V D + +D + P + L G ++GRNIW D A+
Sbjct: 251 L--QGNLALATSLPVDGLHVDAINARDEVDALARELPAERVLSVGAINGRNIWKTDLNAT 308
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
L LE L +G D+L ++ SCSLLH VDL +E KLD EI+SW+AFA QK+ E+ LA
Sbjct: 309 LDWLEPLAKRLG-DRLWLAPSCSLLHVPVDLASEEKLDAEIRSWLAFALQKLDELKVLAT 367
Query: 1772 ALAGHKDEA--LFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQ 1945
AL +D+ +ANAAA+ SRR SPRV N V+ A A + R + + R Q
Sbjct: 368 ALNEGRDKVADALAANAAAIHSRRHSPRVNNPAVKAAIARIDAQLGNRVSPYTQRAPKQS 427
Query: 1946 KKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDID 2125
+LNLP PTTTIGSFPQT E+R+ R ++KA + E Y KAM+ EI++ V QE L++D
Sbjct: 428 ARLNLPAFPTTTIGSFPQTGEIRQARSQFKAGTLDEAGYRKAMQAEIERSVREQESLELD 487
Query: 2126 VLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSA 2305
VLVHGE ERNDMVEYFGEQL G+AF+ GWVQSYGSRCVKPP+++GD+SRPKAMTV W
Sbjct: 488 VLVHGEAERNDMVEYFGEQLDGYAFSQFGWVQSYGSRCVKPPILFGDISRPKAMTVEWIT 547
Query: 2306 MAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQI 2485
AQS+T++PMKGMLTGPVTILNWSFVR+DQPR +CYQ+ALAI++EV DLEK G+ VIQI
Sbjct: 548 YAQSLTNKPMKGMLTGPVTILNWSFVRDDQPRSVSCYQLALAIREEVLDLEKAGVRVIQI 607
Query: 2486 DEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMD 2665
DEAALREGLPLR+++ YL WAV SFRIT GVQD TQIHTHMCYS FNDII SI DMD
Sbjct: 608 DEAALREGLPLRRAQWGEYLKWAVESFRITANGVQDDTQIHTHMCYSEFNDIIASIADMD 667
Query: 2666 ADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQ 2845
ADVITIE SRSD +LL F + KY IGPGVYDIHSP IP+ E I + K +
Sbjct: 668 ADVITIETSRSDMELLDAF-DNFKYPNEIGPGVYDIHSPNIPTQEHIVGLMKKAAERIPA 726
Query: 2846 NILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQL 2956
LWVNPDCGLKTR++ EV PAL NMV AAK +R+Q+
Sbjct: 727 ERLWVNPDCGLKTRQWAEVIPALTNMVAAAKTLRNQV 763
>sp|B1Z0R8|METE_BURA4 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Burkholderia ambifaria (strain MC40-6) GN=metE
PE=3 SV=1
Length = 764
Score = 602 bits (1551), Expect = 6e-171
Identities = 318/577 (55%), Positives = 398/577 (68%), Gaps = 8/577 (1%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY ++ L A G W+Q+DEP+LV +L+ QA AYA LE+ + VL+ TYF
Sbjct: 193 VYGALLDTLTAQGVEWVQIDEPILVTELDAEWRQALRTAYAALET--RRIKVLLATYFGA 250
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ TL + V D + +D + P + L G ++GRNIW D A+
Sbjct: 251 LGDNL--TLAASLPVDGLHVDAINARDEVDALVRELPADRVLSVGAINGRNIWKTDLNAT 308
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
L LE L +G ++L ++ SCSLLH VDL +E KLD EI+SW+AFA QK+ E+N LA
Sbjct: 309 LDWLEPLAKQLG-ERLWIAPSCSLLHVPVDLASEQKLDPEIRSWLAFALQKLDELNVLAT 367
Query: 1772 ALAGHKDEA--LFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQ 1945
AL +D+ +ANAAA+ SRR SPRV N V+ A A + RA+ + R Q
Sbjct: 368 ALNEGRDKVADALAANAAAIDSRRRSPRVNNPAVKAALARIDAQLGNRASPYTQRAPKQS 427
Query: 1946 KKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDID 2125
+LNLP PTTTIGSFPQT ++R+ RR++K+ + E Y AM+ EI++ V QE L++D
Sbjct: 428 ARLNLPAFPTTTIGSFPQTADIRQARRQFKSGALDEAGYRAAMQAEIERSVREQESLELD 487
Query: 2126 VLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSA 2305
VLVHGE ERNDMVEYFGEQL G+AF+ GWVQSYGSRCVKPP+++GD+SRPKAMTV W
Sbjct: 488 VLVHGEAERNDMVEYFGEQLDGYAFSQFGWVQSYGSRCVKPPILFGDISRPKAMTVEWIT 547
Query: 2306 MAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQI 2485
AQS+T++PMKGMLTGPVTILNWSFVR+DQPR +CYQ+ALAI+DEV DLEK G+ VIQI
Sbjct: 548 YAQSLTNKPMKGMLTGPVTILNWSFVRDDQPRSVSCYQLALAIRDEVLDLEKAGVRVIQI 607
Query: 2486 DEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMD 2665
DEAALREGLPLR+++ YL WAV +FRIT GVQD TQIHTHMCYS FNDII SI DMD
Sbjct: 608 DEAALREGLPLRRAQWGEYLKWAVEAFRITANGVQDDTQIHTHMCYSEFNDIIASIADMD 667
Query: 2666 ADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQ 2845
ADVITIE SRSD +LL F + +Y IGPGVYDIHSP IP+ + I + K +
Sbjct: 668 ADVITIETSRSDMELLDAF-DSFRYPNEIGPGVYDIHSPNIPTQDHIVGLMKKAAERIPA 726
Query: 2846 NILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQL 2956
LWVNPDCGLKTR++ EV PAL NMV AAK +R+Q+
Sbjct: 727 ERLWVNPDCGLKTRQWAEVIPALTNMVAAAKTLRNQV 763
>sp|Q1BQX8|METE_BURCA 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Burkholderia cenocepacia (strain AU 1054) GN=metE
PE=3 SV=1
Length = 764
Score = 601 bits (1548), Expect = 1e-170
Identities = 320/577 (55%), Positives = 398/577 (68%), Gaps = 8/577 (1%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY ++ L A G W+Q+DEP+LV +L+ QAF AYA LE+ + +L+ TYF
Sbjct: 193 VYGALLDTLTAQGVEWVQIDEPILVTELDAEWRQAFRTAYAALET--RRIKLLLATYFGQ 250
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ + TL + V D + +D + P + L G ++GRNIW D A+
Sbjct: 251 L--QDNLTLAASLPVDGLHIDAINARDEVDALVRELPAERVLSVGAINGRNIWKTDLNAA 308
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
L LE L +G D+L ++ SCSLLH VDL +E KLD EI+SW+AFA QK+ E+ LA
Sbjct: 309 LDWLEPLAKQLG-DRLWLAPSCSLLHVPVDLASEEKLDAEIRSWLAFALQKLDELKVLAT 367
Query: 1772 ALAGHKDEA--LFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQ 1945
AL +D+ +ANAAA+ SRR SPRV N V+ A A + RA+ + R Q
Sbjct: 368 ALNEGRDKVADALAANAAAIDSRRRSPRVNNPVVKAAIARIDAQLGNRASPYTQRASKQS 427
Query: 1946 KKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDID 2125
+LNLP PTTTIGSFPQT E+R+ R ++A + E Y AM+ EI++ V QE L++D
Sbjct: 428 ARLNLPAFPTTTIGSFPQTAEIRQARSRFRAGALDEAGYRTAMRAEIERSVREQESLELD 487
Query: 2126 VLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSA 2305
VLVHGE ERNDMVEYFGEQL G+AF+ GWVQSYGSRCVKPP+++GD+SRPKAMTV W A
Sbjct: 488 VLVHGEAERNDMVEYFGEQLDGYAFSQFGWVQSYGSRCVKPPILFGDISRPKAMTVEWIA 547
Query: 2306 MAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQI 2485
AQS+T +PMKGMLTGPVTILNWSFVR+DQPR +CYQ+ALAI++EV DLEK G+ VIQI
Sbjct: 548 YAQSLTRKPMKGMLTGPVTILNWSFVRDDQPRAVSCYQLALAIREEVLDLEKAGVRVIQI 607
Query: 2486 DEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMD 2665
DEAALREGLPLR+++ + YL WAV SFRIT GVQD TQIHTHMCYS FNDII SI DMD
Sbjct: 608 DEAALREGLPLRRAQWSEYLKWAVESFRITANGVQDDTQIHTHMCYSEFNDIIASIADMD 667
Query: 2666 ADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQ 2845
ADVITIE SRSD +LL F + KY IGPGVYDIHSP IP+ + I + K +
Sbjct: 668 ADVITIETSRSDMELLDAF-DTFKYPNEIGPGVYDIHSPNIPTQDHIVGLMKKAAERIPA 726
Query: 2846 NILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQL 2956
LWVNPDCGLKTR++ EV PAL NMV AAK +R+Q+
Sbjct: 727 ERLWVNPDCGLKTRQWAEVIPALTNMVAAAKTLRNQV 763
>sp|A0B2Z3|METE_BURCH 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Burkholderia cenocepacia (strain HI2424) GN=metE
PE=3 SV=1
Length = 764
Score = 601 bits (1548), Expect = 1e-170
Identities = 320/577 (55%), Positives = 398/577 (68%), Gaps = 8/577 (1%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY ++ L A G W+Q+DEP+LV +L+ QAF AYA LE+ + +L+ TYF
Sbjct: 193 VYGALLDTLTAQGVEWVQIDEPILVTELDAEWRQAFRTAYAALET--RRIKLLLATYFGQ 250
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ + TL + V D + +D + P + L G ++GRNIW D A+
Sbjct: 251 L--QDNLTLAASLPVDGLHIDAINARDEVDALVRELPAERVLSVGAINGRNIWKTDLNAA 308
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
L LE L +G D+L ++ SCSLLH VDL +E KLD EI+SW+AFA QK+ E+ LA
Sbjct: 309 LDWLEPLAKQLG-DRLWLAPSCSLLHVPVDLASEEKLDAEIRSWLAFALQKLDELKVLAT 367
Query: 1772 ALAGHKDEA--LFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQ 1945
AL +D+ +ANAAA+ SRR SPRV N V+ A A + RA+ + R Q
Sbjct: 368 ALNEGRDKVADALAANAAAIDSRRRSPRVNNPVVKAAIARIDAQLGNRASPYTQRASKQS 427
Query: 1946 KKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDID 2125
+LNLP PTTTIGSFPQT E+R+ R ++A + E Y AM+ EI++ V QE L++D
Sbjct: 428 ARLNLPAFPTTTIGSFPQTAEIRQARSRFRAGALDEAGYRTAMRAEIERSVREQESLELD 487
Query: 2126 VLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSA 2305
VLVHGE ERNDMVEYFGEQL G+AF+ GWVQSYGSRCVKPP+++GD+SRPKAMTV W A
Sbjct: 488 VLVHGEAERNDMVEYFGEQLDGYAFSQFGWVQSYGSRCVKPPILFGDISRPKAMTVEWIA 547
Query: 2306 MAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQI 2485
AQS+T +PMKGMLTGPVTILNWSFVR+DQPR +CYQ+ALAI++EV DLEK G+ VIQI
Sbjct: 548 YAQSLTRKPMKGMLTGPVTILNWSFVRDDQPRAVSCYQLALAIREEVLDLEKAGVRVIQI 607
Query: 2486 DEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMD 2665
DEAALREGLPLR+++ + YL WAV SFRIT GVQD TQIHTHMCYS FNDII SI DMD
Sbjct: 608 DEAALREGLPLRRAQWSEYLKWAVESFRITANGVQDDTQIHTHMCYSEFNDIIASIADMD 667
Query: 2666 ADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQ 2845
ADVITIE SRSD +LL F + KY IGPGVYDIHSP IP+ + I + K +
Sbjct: 668 ADVITIETSRSDMELLDAF-DTFKYPNEIGPGVYDIHSPNIPTQDHIVGLMKKAAERIPA 726
Query: 2846 NILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQL 2956
LWVNPDCGLKTR++ EV PAL NMV AAK +R+Q+
Sbjct: 727 ERLWVNPDCGLKTRQWAEVIPALTNMVAAAKTLRNQV 763
>sp|Q0B6M7|METE_BURCM 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Burkholderia ambifaria (strain ATCC BAA-244 /
AMMD) GN=metE PE=3 SV=1
Length = 764
Score = 597 bits (1539), Expect = 2e-169
Identities = 317/577 (54%), Positives = 394/577 (68%), Gaps = 8/577 (1%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY ++ L A G W+Q+DEP+LV +L+ QA AYA LE+ + +L+ TYF
Sbjct: 193 VYGALLDTLTAQGVEWVQIDEPILVTELDAEWRQALRTAYAALET--RRIKLLLATYFGT 250
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ TL + V D + +D + P + L G ++GRNIW D A+
Sbjct: 251 LGDNL--TLAASLPVDGLHVDAINARDEVDALVRELPADRVLSVGAINGRNIWKTDLNAT 308
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
L LE L +G D+L ++ SCSLLH VDL +E KLD EI+SW+AFA QK+ E+ LA
Sbjct: 309 LDWLEPLAKQLG-DRLWIAPSCSLLHVPVDLASEEKLDAEIRSWLAFALQKLDELKVLAT 367
Query: 1772 ALAGHKDEA--LFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQ 1945
AL +D+ +ANAAA+ SRR SPRV N V+ A A + RA+ + R Q
Sbjct: 368 ALNQGRDKVADALAANAAAIDSRRRSPRVNNPAVKAALARIDAQLGNRASPYTQRAPKQS 427
Query: 1946 KKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDID 2125
+LNLP PTTTIGSFPQT ++R R ++KA + E Y AM+ EI++ V QE L +D
Sbjct: 428 ARLNLPAFPTTTIGSFPQTADIRHARSQFKAGALDEAGYRAAMQAEIERSVREQESLGLD 487
Query: 2126 VLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSA 2305
VLVHGE ERNDMVEYFGEQL G+AF+ GWVQSYGSRCVKPP+++GD+SRPKAMTV W
Sbjct: 488 VLVHGEAERNDMVEYFGEQLDGYAFSQFGWVQSYGSRCVKPPILFGDISRPKAMTVEWIT 547
Query: 2306 MAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQI 2485
AQS+T++PMKGMLTGPVTILNWSFVR+DQPR +CYQ+ALAI+DEV DLEK G+ VIQI
Sbjct: 548 YAQSLTNKPMKGMLTGPVTILNWSFVRDDQPRSVSCYQLALAIRDEVLDLEKAGVRVIQI 607
Query: 2486 DEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMD 2665
DEAALREGLPLR+++ YL WAV +FRIT GVQD TQIHTHMCYS FNDII SI DMD
Sbjct: 608 DEAALREGLPLRRAQWGEYLKWAVEAFRITANGVQDDTQIHTHMCYSEFNDIIASIADMD 667
Query: 2666 ADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQ 2845
ADVITIE SRSD +LL F + +Y IGPGVYDIHSP IP+ + I + K +
Sbjct: 668 ADVITIETSRSDMELLDAF-DSFRYPNEIGPGVYDIHSPNIPTQDHIVGLMKKAAERIPA 726
Query: 2846 NILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQL 2956
LWVNPDCGLKTR++ EV PAL NMV AAK +R+Q+
Sbjct: 727 ERLWVNPDCGLKTRQWAEVIPALTNMVAAAKTLRNQV 763
>sp|A4JJS1|METE_BURVG 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Burkholderia vietnamiensis (strain G4 / LMG 22486)
GN=metE PE=3 SV=1
Length = 767
Score = 592 bits (1525), Expect = 7e-168
Identities = 316/577 (54%), Positives = 392/577 (67%), Gaps = 8/577 (1%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY ++ L A G W+Q+DEP+LV +L+ +A AY LE+ + +L+ TYF
Sbjct: 193 VYGALLDTLTAQGVEWVQIDEPILVTELDADWRRALRTAYEALET--RRIKLLLATYFGQ 250
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ + + SL V D V +D + P + L G +DGRNIW D A+
Sbjct: 251 L-QDNLELAVSLP-VDGLHIDAVNARDEVDALARALPPTRVLSVGAIDGRNIWRTDLNAA 308
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
L LE L +G ++L ++ SCSLLH VDL +E KLD EI+SW+AFA QK+ E+ LA
Sbjct: 309 LDWLEPLARQLG-ERLWLAPSCSLLHVPVDLASEQKLDAEIRSWLAFALQKLAELKLLAT 367
Query: 1772 ALAGHKDEA--LFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQ 1945
AL +D + NAAA+ SRR SPRV N V+ A A + RA+ R AQ
Sbjct: 368 ALNQGRDTVADALAENAAAIESRRRSPRVHNPAVKSAVARIDARLGNRASAYPQRAAAQS 427
Query: 1946 KKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDID 2125
+L LP+ PTTTIGSFPQT E+R RR +KA ++ E Y AM EI++ V QE L +D
Sbjct: 428 ARLKLPLFPTTTIGSFPQTAEIRDARRRFKAGELDEAGYRHAMHAEIERSVREQESLQLD 487
Query: 2126 VLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSA 2305
VLVHGE ERNDMVEYFGEQL G+AF+ GWVQSYGSRCVKPP+++GD+SRP AMTV W A
Sbjct: 488 VLVHGEAERNDMVEYFGEQLDGYAFSQFGWVQSYGSRCVKPPILFGDISRPSAMTVEWIA 547
Query: 2306 MAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQI 2485
AQS+TS+PMKGMLTGPVTILNWSFVR+DQPR +CYQ+ALAI+DEV DLE+ G+ VIQI
Sbjct: 548 YAQSLTSKPMKGMLTGPVTILNWSFVRDDQPRSVSCYQLALAIRDEVLDLERAGVRVIQI 607
Query: 2486 DEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMD 2665
DEAALREGLPLR+++ YL WA+ +FRI GV+D TQIHTHMCYS FNDII SI +MD
Sbjct: 608 DEAALREGLPLRRAQWPAYLKWAIDAFRIAANGVRDDTQIHTHMCYSEFNDIIASIAEMD 667
Query: 2666 ADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQ 2845
ADVITIE SRSD +LL F +G +Y IGPGVYDIHSP IP+ E I + K +
Sbjct: 668 ADVITIETSRSDMELLDAF-DGFRYPNEIGPGVYDIHSPNIPTQEHIVGLMRKAAERIPA 726
Query: 2846 NILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQL 2956
LWVNPDCGLKTR++ EV PAL NMV AAK +RS+L
Sbjct: 727 QRLWVNPDCGLKTRRWAEVLPALTNMVAAAKTLRSEL 763
>sp|Q8XS05|METE_RALSO 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Ralstonia solanacearum GN=metE PE=3 SV=1
Length = 776
Score = 583 bits (1502), Expect = 3e-165
Identities = 313/579 (54%), Positives = 394/579 (68%), Gaps = 8/579 (1%)
Frame = +2
Query: 1235 YREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFADI 1414
Y V+ L A G W+Q+DEP LV+DL A+ AYA L + G +L+ TYF
Sbjct: 186 YAAVLKRLAAEGVEWVQIDEPALVLDLPQAWSDAYGPAYATL-AAAGGPRLLLATYFE-- 242
Query: 1415 PAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAASL 1594
A + L V DLVR + L+ A +P K L AGVVDGRNIW D +L
Sbjct: 243 AASHHAALIRSLPVAGVHLDLVRAPQQLEAF-APWPADKVLSAGVVDGRNIWRTDLEQAL 301
Query: 1595 STLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAKA 1774
+ + L +G ++L ++ SCSLLH VDL ET+LDDE+K W+AFA QK+ E+ L +A
Sbjct: 302 ARVAPLAQTLG-ERLWLAPSCSLLHVPVDLAAETRLDDELKGWLAFARQKLDELAVLKRA 360
Query: 1775 LAGHKD--EALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQK 1948
+ +D A + +AAA+ASR +S RV N+ V+K AAA++ D RA R AQQ
Sbjct: 361 VIDGRDAAHAALAGSAAAIASRAASRRVHNDSVKKRAAAIRAQDAERAAPYPVRAAAQQA 420
Query: 1949 KLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDIDV 2128
+LNLP+LPTTTIGSFPQT E+R+ R +YK ++ Y++ M+ EI VV QE L +D+
Sbjct: 421 RLNLPLLPTTTIGSFPQTAEIRQARAQYKRGELQALTYLERMRAEIADVVQRQEALGLDM 480
Query: 2129 LVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSAM 2308
LVHGE ERNDMVEYFGE L G+AFTANGWVQSYGSRCVKPPVIYGDV RP+ MTV WS
Sbjct: 481 LVHGEAERNDMVEYFGELLWGYAFTANGWVQSYGSRCVKPPVIYGDVYRPEPMTVEWSRY 540
Query: 2309 AQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQID 2488
AQS+T++PMKGMLTGPVT+L WSFVR+DQPR +T QIALA++DEV DLE GI IQID
Sbjct: 541 AQSLTAKPMKGMLTGPVTMLQWSFVRDDQPREQTALQIALALRDEVRDLEAAGIAAIQID 600
Query: 2489 EAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMDA 2668
E A REGLPLR + A YL+WA FR++ GV++ TQIHTHMCYS FNDI+ +I MDA
Sbjct: 601 EPAFREGLPLRAGDVAVYLEWAARVFRVSASGVRNDTQIHTHMCYSEFNDILPAIASMDA 660
Query: 2669 DVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQN 2848
DVITIE SRS+ +LL F E Y IGPGVYDIHSPR+P EE+ ++K V+
Sbjct: 661 DVITIETSRSNMELLDAFGE-FAYPNEIGPGVYDIHSPRVPRVEEMEALLDKAAQVVPVQ 719
Query: 2849 ILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASA 2965
LWVNPDCGLKTR + EV+ AL+ MV+A + +R++ A A
Sbjct: 720 RLWVNPDCGLKTRGWPEVEAALRGMVEATRRLRARHAGA 758
>sp|A1TYT7|METE_MARAV 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Marinobacter aquaeolei (strain ATCC 700491 / DSM
11845 / VT8) GN=metE PE=3 SV=1
Length = 756
Score = 579 bits (1491), Expect = 6e-164
Identities = 305/574 (53%), Positives = 397/574 (69%), Gaps = 8/574 (1%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY +++ L AGA W+QLDEP LV DL+ + AF AY +L++ L L+ TYF +
Sbjct: 188 VYSQLLEALADAGAEWVQLDEPALVTDLDANWRYAFNLAYHQLKANRPKL--LLATYFGE 245
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ L V D + + V P K L GVV+GRNIW +D ++
Sbjct: 246 LRDNL--QLACELPVAGLHIDAISAPAEVSRVADWLPSHKVLSLGVVNGRNIWKSDLNST 303
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
L LE L +G+ +L ++ SCSLLH VDL E +LD +I++W+AFA QK+ E+ LA+
Sbjct: 304 LGWLEPLNEKLGQ-RLWLAPSCSLLHAPVDLSREQELDSDIRNWLAFAVQKLDELQILAR 362
Query: 1772 ALAGHKD--EALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQ 1945
AL + A + N A+ SRR+S RVTN V+KA A++ R + R+ Q+
Sbjct: 363 ALNEGRSSVRAELADNQLAIDSRRNSHRVTNPEVRKAVASVTPELGNRHSPYPQRIARQR 422
Query: 1946 KKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDID 2125
++LNLP PTTTIGSFPQT E+R+ R +++ ++SE+ Y++ M+ EI + V+ QE+L +D
Sbjct: 423 ERLNLPAFPTTTIGSFPQTREIRQARLQFRKGELSEQAYIEQMRAEIVRCVEAQEKLGLD 482
Query: 2126 VLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSA 2305
VLVHGEPERNDMVEYFGEQL G+AFT GWVQSYGSRCVKPP+++GD+ RP+AMTV W
Sbjct: 483 VLVHGEPERNDMVEYFGEQLDGYAFTRFGWVQSYGSRCVKPPILFGDIRRPQAMTVEWIR 542
Query: 2306 MAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQI 2485
AQS+T +P+KGMLTGPVTILNWSFVR+DQPR ++C Q+ALAI++EV+DLEK G+ +IQI
Sbjct: 543 YAQSLTDKPVKGMLTGPVTILNWSFVRDDQPRKDSCLQLALAIREEVQDLEKAGVNIIQI 602
Query: 2486 DEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMD 2665
DEAALREGLPLR+S+ A YL+WA++SFRI GV DSTQIHTHMCYS FNDII +I MD
Sbjct: 603 DEAALREGLPLRQSDWATYLEWAINSFRIAANGVDDSTQIHTHMCYSEFNDIIEAIARMD 662
Query: 2666 ADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQ 2845
ADVITIE SRSD +LL FR +Y IGPGVYDIHSP IP E I + + +
Sbjct: 663 ADVITIETSRSDMELLDAFR-SFEYPNDIGPGVYDIHSPNIPDKEHIINLMTLAAERIPA 721
Query: 2846 NILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIR 2947
LW+NPDCGLKTRK+ EV PAL+ MV AA+ +R
Sbjct: 722 ERLWINPDCGLKTRKWEEVTPALETMVAAARELR 755
>sp|Q1QZS5|METE_CHRSD 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Chromohalobacter salexigens (strain DSM 3043 /
ATCC BAA-138 / NCIMB 13768) GN=metE PE=3 SV=1
Length = 761
Score = 576 bits (1483), Expect = 5e-163
Identities = 312/575 (54%), Positives = 381/575 (66%), Gaps = 9/575 (1%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY E++ L A G W+QLDEP LV DL QAF AY +L+S + + +L+ TYF
Sbjct: 189 VYGEILERLAAQGVEWVQLDEPALVQDLPRDWRQAFESAYNKLQS--APVKLLLATYFGA 246
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ L + V D VR + LD V P K L G +DGRNIW D AA
Sbjct: 247 LGDNL--GLAAGLPVAGLHIDTVRAPEQLDAVLDRLPTYKVLSLGAIDGRNIWRADLAAL 304
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
L+ +G ++L +S SCSLLH VDL ET LD E+KSW+AFA QK+ E+ LA
Sbjct: 305 RERLQVARARLG-ERLWISASCSLLHVPVDLDAETDLDAELKSWLAFARQKLDEIVTLAH 363
Query: 1772 ALAGH---KDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQ 1942
L G +D A A +AL +RR SPR+ V + AA+ D RA+ + R AQ
Sbjct: 364 LLDGRATPEDTARLEAATSALDARRQSPRIHKPAVGERLAAVSADDAERASPYATRAKAQ 423
Query: 1943 QKKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDI 2122
+ L+LP+ PTTTIGSFPQT ++R RR +K+ ++S +DY M++EI V+ QE L I
Sbjct: 424 HRHLDLPLFPTTTIGSFPQTQDIRAARRAFKSGELSRDDYEARMRDEIAHAVERQEALAI 483
Query: 2123 DVLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWS 2302
DV VHGEPERNDMVEYFGE L GFAFT GWVQSYGSRCVKPPVI+GDVSRP MTV WS
Sbjct: 484 DVPVHGEPERNDMVEYFGELLDGFAFTRFGWVQSYGSRCVKPPVIFGDVSRPGPMTVRWS 543
Query: 2303 AMAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQ 2482
AQS+T +PMKGMLTGPVTIL WSFVR+DQPR TC QIAL+++DEV DLE GI +IQ
Sbjct: 544 EYAQSLTDKPMKGMLTGPVTILQWSFVRDDQPRDATCRQIALSLRDEVADLEAAGIKIIQ 603
Query: 2483 IDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDM 2662
IDE ALREGLPLR+ E YLDWAV SF+++ +D TQIHTHMCYS FNDII +I +
Sbjct: 604 IDEPALREGLPLRQGEWQEYLDWAVKSFKLSAAVARDETQIHTHMCYSEFNDIIAAIAAL 663
Query: 2663 DADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLE 2842
DADVITIE SRSD +LL F++ Y IGPGVYDIHSP IP E + + K +
Sbjct: 664 DADVITIETSRSDMELLDAFQD-FAYPNEIGPGVYDIHSPNIPEVEWMVSLMEKAAEKIP 722
Query: 2843 QNILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIR 2947
LWVNPDCGLKTR + EV+PAL NMV+AA+ +R
Sbjct: 723 AERLWVNPDCGLKTRGWAEVEPALANMVEAARELR 757
>sp|B2JNZ4|METE_BURP8 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Burkholderia phymatum (strain DSM 17167 / STM815)
GN=metE PE=3 SV=1
Length = 763
Score = 575 bits (1482), Expect = 6e-163
Identities = 312/574 (54%), Positives = 381/574 (66%), Gaps = 8/574 (1%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY ++ A G W+Q+DEPVLV +L+ AF AY L + + VL+ TYF
Sbjct: 193 VYAALLDYFTAQGIDWVQIDEPVLVTELDARWRDAFVPAYDALAA--RRVRVLLATYFGQ 250
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ L V D + + V A PE L GV++GRN+W D A+
Sbjct: 251 LKENL--ELACQLPVDGLHIDAIHARDEVAQVAAQVPETAVLSVGVINGRNVWKTDLNAA 308
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALAK 1771
L+ LE L +G D+L ++ SCSLLH+ VDL +E KLD +I+SW+AFA QK+ E+ LA
Sbjct: 309 LAWLEPLHATLG-DRLWIAPSCSLLHSPVDLNSERKLDADIRSWLAFALQKLDELTLLAS 367
Query: 1772 ALAGHKD--EALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQ 1945
AL + EA ANA A+ SRR+SPRV N V+ A A + S +RA AR Q
Sbjct: 368 ALNNGRACVEAELLANAKAIESRRASPRVHNAAVKAALARIDASLGQRANAYPARAAKQA 427
Query: 1946 KKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEELDID 2125
L LP PTTTIGSFPQT ++RR R ++KA ++ Y AM+ EI + V QE L +D
Sbjct: 428 AALALPAFPTTTIGSFPQTADIRRARSQFKAGELDYAGYKLAMEREITRAVKEQETLGLD 487
Query: 2126 VLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSA 2305
VLVHGE ERNDMVEYFGEQL G+ F+ GWVQSYGSRCVKPP+++GD+SRPKAMTV W
Sbjct: 488 VLVHGEAERNDMVEYFGEQLDGYVFSQFGWVQSYGSRCVKPPILFGDISRPKAMTVEWIC 547
Query: 2306 MAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQI 2485
AQ+ T++PMKGMLTGPVTILNWSFVR+DQPR +C Q+ALAI++EV DLEK G+ VIQI
Sbjct: 548 YAQAQTAKPMKGMLTGPVTILNWSFVRDDQPRSVSCRQLALAIREEVLDLEKAGVRVIQI 607
Query: 2486 DEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMD 2665
DEAALREGLPLR+S+ YL WAV SFRI GVQD TQIHTHMCYS FNDII SI +MD
Sbjct: 608 DEAALREGLPLRRSQWNEYLQWAVESFRIAANGVQDETQIHTHMCYSEFNDIIASIAEMD 667
Query: 2666 ADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQ 2845
ADVITIE SRSD +LL F + Y IGPGVYDIHSP IP + D + K +
Sbjct: 668 ADVITIETSRSDMELLDAF-DDFHYPNQIGPGVYDIHSPNIPDQAHVVDLMKKAAERIPA 726
Query: 2846 NILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIR 2947
LWVNPDCGLKTR + EV PALKNMV AA+ +R
Sbjct: 727 ERLWVNPDCGLKTRAWEEVIPALKNMVAAARTLR 760
>sp|B2UJ81|METE_RALPJ 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Ralstonia pickettii (strain 12J) GN=metE PE=3
SV=1
Length = 776
Score = 568 bits (1463), Expect = 1e-160
Identities = 317/587 (54%), Positives = 389/587 (66%), Gaps = 22/587 (3%)
Frame = +2
Query: 1235 YREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFADI 1414
Y V+ L A W+Q+DEP LV+DL + AF A+ L + G L+ TYF
Sbjct: 189 YTAVLQRLAALKVEWVQIDEPALVLDLPQAWVDAFGPAHQAL-AAAKGPKRLLATYFE-- 245
Query: 1415 PAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFP--EGKYLFAGVVDGRNIWANDFAA 1588
A + L V DLVR D V A P K L GVVDGRNIW D
Sbjct: 246 AASHHAALIQSLPVDGVHLDLVRAP---DQVAAFAPWSADKVLSVGVVDGRNIWRTDLTR 302
Query: 1589 SLSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWMAFAAQKVVEVNALA 1768
L+ L L +G D+L ++ SCSLLH VDL ETKLDDE+K W+AFA QK+ E+ +
Sbjct: 303 VLAHLTPLAQALG-DRLWIAPSCSLLHVPVDLSAETKLDDELKGWLAFARQKLDELAVIK 361
Query: 1769 KALA-------GHKDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSA 1927
+AL G D+ N A+ASR S RV N GV+K AA++ +D RA A
Sbjct: 362 RALVEGPAAVQGELDD-----NRIAIASRTQSRRVHNAGVKKRVAAIRAADAVRAAPYPA 416
Query: 1928 RLDAQQKKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQ 2107
R DAQQ +LNLP+LPTTTIGSFPQT E+RR R ++K + DY++ M+ EI VV Q
Sbjct: 417 RADAQQARLNLPLLPTTTIGSFPQTPEIRRARAQHKRGDLPALDYLQRMRTEIADVVRRQ 476
Query: 2108 EELDIDVLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAM 2287
E L +D+LVHGE ERNDMVEYFGE L G+AFTANGWVQSYGSRCVKPPVIYGDV RP+AM
Sbjct: 477 EALGLDMLVHGEAERNDMVEYFGELLWGYAFTANGWVQSYGSRCVKPPVIYGDVYRPEAM 536
Query: 2288 TVFWSAMAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGG 2467
TV WS AQS+TS+PMKGMLTGPVT+L WSFVR+DQPR +T QIALA++DEV DLE G
Sbjct: 537 TVEWSKYAQSLTSKPMKGMLTGPVTMLQWSFVRDDQPREQTALQIALALRDEVCDLEAAG 596
Query: 2468 IGVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIH 2647
I IQIDE A REGLPLR S+ YL+WA +FR++ GV++ TQIHTHMCYS FNDI+
Sbjct: 597 IAAIQIDEPAFREGLPLRASDVPTYLEWAARAFRVSASGVRNDTQIHTHMCYSEFNDILP 656
Query: 2648 SIIDMDADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKM 2827
+I MDADVITIE SRS+ +LL F E Y IGPGVYDIHSPR+P +E+ ++K
Sbjct: 657 AIASMDADVITIETSRSNMELLDAFAE-FAYPNEIGPGVYDIHSPRVPRVDEMESLLDKA 715
Query: 2828 LAVLEQNILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASAK 2968
V+ LWVNPDCGLKTR + EV+ AL+ +V+A +R++ A+AK
Sbjct: 716 AQVVPVQRLWVNPDCGLKTRGWPEVEAALQGIVEATHRLRAKHANAK 762
>sp|Q9JUT6|METE_NEIMA 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Neisseria meningitidis serogroup A GN=metE PE=3
SV=1
Length = 758
Score = 565 bits (1455), Expect = 9e-160
Identities = 313/581 (53%), Positives = 388/581 (66%), Gaps = 14/581 (2%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY E++T L AGA WIQ+DEP L +DL ++A+ YA L +L+ TYF
Sbjct: 186 VYVEILTALVEAGAEWIQIDEPALTVDLPKEWVEAYKDVYATLSKV--SAKILLSTYFGS 243
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ AE L SL V DLVR + LD A K L AGV+DGRNIW +
Sbjct: 244 V-AEHAALLKSLP-VDGLHIDLVRAPEQLD---AFADYDKVLSAGVIDGRNIWRANLNKV 298
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKL---DDEIKSWMAFAAQKVVEVNA 1762
L T+E L+ +G D+L +S+SCSLLHT DL E KL ++ SW+AF QK E+
Sbjct: 299 LETVELLQAKLG-DRLWISSSCSLLHTPFDLSVEEKLKANKPDLYSWLAFTLQKTQELRV 357
Query: 1763 LAKALAGHKDEAL--FSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLD 1936
L AL +D +A+ AA SR +S + V K A L + +R + + R+
Sbjct: 358 LKAALNEGRDSVAEELAASQAAADSRANSSEIHRADVAKRLADLPANADQRKSPFADRIK 417
Query: 1937 AQQKKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEEL 2116
AQQ LNLP+LPTT IGSFPQT E+R+ R +K ++S DY AMK+EI VV+ QE+L
Sbjct: 418 AQQAWLNLPLLPTTNIGSFPQTTEIRQARAAFKKGELSAADYEAAMKKEIALVVEEQEKL 477
Query: 2117 DIDVLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVF 2296
D+DVLVHGE ERNDMVEYFGE LSGFAFT GWVQSYGSRCVKPP+I+GDVSRP+AMTV
Sbjct: 478 DLDVLVHGEAERNDMVEYFGELLSGFAFTQYGWVQSYGSRCVKPPIIFGDVSRPEAMTVA 537
Query: 2297 WSAMAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGV 2476
WS AQS+T RPMKGMLTGPVTIL WSFVRND PR C QIALA+ DEV DLEK GI V
Sbjct: 538 WSTYAQSLTKRPMKGMLTGPVTILQWSFVRNDIPRSTVCKQIALALNDEVLDLEKAGIKV 597
Query: 2477 IQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSII 2656
IQIDE A+REGLPL++++ YL+WA SFR+++ G +DSTQIHTHMCYS FNDI+ +I
Sbjct: 598 IQIDEPAIREGLPLKRADWDAYLNWAGESFRLSSTGCEDSTQIHTHMCYSEFNDILPAIA 657
Query: 2657 DMDADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAV 2836
MDADVITIE SRSD +LL+ F E KY IGPGVYDIHSPR+P+ E+ + K + V
Sbjct: 658 AMDADVITIETSRSDMELLTAFGE-FKYPNDIGPGVYDIHSPRVPTEAEVEHLLRKAIEV 716
Query: 2837 LEQNILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLA 2959
+ LWVNPDCGLKTR + E L+ M++ +R++LA
Sbjct: 717 VPVERLWVNPDCGLKTRGWKETLEQLQVMMNVTHKLRAELA 757
>sp|Q9JZQ2|METE_NEIMB 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Neisseria meningitidis serogroup B GN=metE PE=1
SV=1
Length = 758
Score = 564 bits (1453), Expect = 1e-159
Identities = 309/581 (53%), Positives = 386/581 (66%), Gaps = 14/581 (2%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY E++T L AGA WIQ+DEP L +DL ++A+ YA L +L+ TYF
Sbjct: 186 VYVEILTALVEAGAEWIQIDEPALAVDLPKEWVEAYKDVYATLSKV--SAKILLSTYFGS 243
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAAS 1591
+ A L V DLVR + LD A K L AGV+DGRNIW +
Sbjct: 244 VAEHA--ALLKALPVDGLHIDLVRAPEQLD---AFADYDKVLSAGVIDGRNIWRANLNKV 298
Query: 1592 LSTLEALEGVVGKDKLVVSTSCSLLHTAVDLINETKL---DDEIKSWMAFAAQKVVEVNA 1762
L T+E L+ +G D+L +S+SCSLLHT DL E KL ++ SW+AF QK E+
Sbjct: 299 LETVEPLQAKLG-DRLWISSSCSLLHTPFDLSVEEKLKANKPDLYSWLAFTLQKTQELRV 357
Query: 1763 LAKALAGHKDEAL--FSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLD 1936
L AL +D +A+ AA SR +S + V K A L + +R + + R+
Sbjct: 358 LKAALNEGRDSVAEELAASQAAADSRANSSEIHRADVAKRLADLPANADQRKSPFADRIK 417
Query: 1937 AQQKKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQEEL 2116
AQQ LNLP+LPTT IGSFPQT E+R+ R +K ++S DY AMK+EI VV+ QE+L
Sbjct: 418 AQQAWLNLPLLPTTNIGSFPQTTEIRQARSAFKKGELSAADYEAAMKKEIALVVEEQEKL 477
Query: 2117 DIDVLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVF 2296
D+DVLVHGE ERNDMVEYFGE LSGFAFT GWVQSYGSRCVKPP+I+GDVSRP+AMTV
Sbjct: 478 DLDVLVHGEAERNDMVEYFGELLSGFAFTQYGWVQSYGSRCVKPPIIFGDVSRPEAMTVA 537
Query: 2297 WSAMAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGV 2476
WS AQS+T RPMKGMLTGPVTIL WSFVRND PR C QIALA+ DEV DLEK GI V
Sbjct: 538 WSTYAQSLTKRPMKGMLTGPVTILQWSFVRNDIPRSTVCKQIALALNDEVLDLEKAGIKV 597
Query: 2477 IQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSII 2656
IQIDE A+REGLPL++++ YL+WA SFR+++ G +DSTQIHTHMCYS FNDI+ +I
Sbjct: 598 IQIDEPAIREGLPLKRADWDAYLNWAGESFRLSSAGCEDSTQIHTHMCYSEFNDILPAIA 657
Query: 2657 DMDADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAV 2836
MDADVITIE SRSD +LL+ F E +Y IGPGVYDIHSPR+P+ E+ + K + V
Sbjct: 658 AMDADVITIETSRSDMELLTAFGE-FQYPNDIGPGVYDIHSPRVPTEAEVEHLLRKAIEV 716
Query: 2837 LEQNILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLA 2959
+ LWVNPDCGLKTR + E L+ M++ + +R++LA
Sbjct: 717 VPVERLWVNPDCGLKTRGWKETLEQLQVMMNVTRKLRAELA 757
>sp|A5FJR8|METE_FLAJ1 5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase OS=Flavobacterium johnsoniae (strain ATCC 17061 / DSM
2064 / UW101) GN=metE PE=3 SV=1
Length = 774
Score = 564 bits (1452), Expect = 2e-159
Identities = 307/580 (52%), Positives = 385/580 (66%), Gaps = 11/580 (1%)
Frame = +2
Query: 1232 VYREVITELKAAGATWIQLDEPVLVMDLEGHKLQAFTGAYAELESTLSGLNVLVETYFAD 1411
VY E++ +L+ A +IQLDEP L ++L + FT Y E+ L +++ YF D
Sbjct: 189 VYFEILEKLQIENAEYIQLDEPFLALNLTDKERNVFTKVYNEINVRFPKLKIVLANYF-D 247
Query: 1412 IPAEAYKTLTSLKGVTAYGFDLVRGTKTLD--LVKAGFPEGKYLFAGVVDGRNIWANDFA 1585
E +T +L V + DLVR LD L L GVVDGRNIW NDF
Sbjct: 248 CFGENLETALALP-VDTFHLDLVRCQLQLDDILESGKLASNVNLSLGVVDGRNIWKNDFK 306
Query: 1586 ASLSTLEALEGVVGKDKLVVSTSCSLLHTAVDL---INETKLDDEIKSWMAFAAQKVVEV 1756
SL ++ +G+++++++ SCSL+H+ DL N+ L EIK W+AFA QK+ EV
Sbjct: 307 KSLELIKKAADALGENRILLAPSCSLIHSPCDLDLETNDQTLTPEIKQWLAFAKQKINEV 366
Query: 1757 NALAKALAGH---KDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSA 1927
L + +G K+ A + N A +R++S + N V+ A + +D +R + ++
Sbjct: 367 VLLKQFASGEVNPKNSADYERNVIANENRKTSKLIHNNEVKARTAGITAADDKRKSAFAS 426
Query: 1928 RLDAQQKKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAMKEEIKKVVDLQ 2107
R +Q K LNLP+ PTTTIGSFPQT E+R R ++K +++ E Y +++E + + Q
Sbjct: 427 RRKSQIKALNLPLFPTTTIGSFPQTTEVRSWRAKFKKGELTTEQYNDLIEKETEAAIRFQ 486
Query: 2108 EELDIDVLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAM 2287
EE IDVLVHGE ERNDMVEYFGEQL GF FT NGWVQSYGSRCVKPPVIYGDVSRP M
Sbjct: 487 EETGIDVLVHGEFERNDMVEYFGEQLDGFTFTKNGWVQSYGSRCVKPPVIYGDVSRPNPM 546
Query: 2288 TVFWSAMAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGG 2467
TV WS AQS+TS+ +KGMLTGPVTIL WSFVRNDQPR ETC QIALA++DEV DLEK G
Sbjct: 547 TVKWSKYAQSLTSKWVKGMLTGPVTILQWSFVRNDQPRSETCTQIALAVRDEVVDLEKAG 606
Query: 2468 IGVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIH 2647
I +IQIDE A+REGLPLRK E A YLDWAV +FRI+ GV D TQIH HMCYS FNDII
Sbjct: 607 IKIIQIDEPAIREGLPLRKEEWAKYLDWAVKAFRISASGVNDDTQIHPHMCYSEFNDIIQ 666
Query: 2648 SIIDMDADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKM 2827
+I DMDADVITIE SRS +LL F KY IGPGVYDIHSPR+PSS+E+ + K
Sbjct: 667 NIADMDADVITIECSRSQMELLDAF-ANFKYPNEIGPGVYDIHSPRVPSSKEMVRLLEKA 725
Query: 2828 LAVLEQNILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIR 2947
AV+ + LWVNPDCGLKTR + E K AL MV AA+ +R
Sbjct: 726 SAVIPVDQLWVNPDCGLKTRHWNETKKALIEMVAAAQEMR 765
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,281,224,270
Number of Sequences: 518415
Number of Extensions: 55281224270
Number of Successful Extensions: 373770181
Number of sequences better than 0.0: 0
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