BLASTX 7.6.2
Query= UN13768 /QuerySize=1366
(1365 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9CLV5|MENB_PASMU Naphthoate synthase OS=Pasteurella multocid... 371 1e-101
sp|P44960|MENB_HAEIN Naphthoate synthase OS=Haemophilus influenz... 370 2e-101
sp|P0ABU1|MENB_ECOL6 Naphthoate synthase OS=Escherichia coli O6 ... 366 3e-100
sp|P0ABU0|MENB_ECOLI Naphthoate synthase OS=Escherichia coli (st... 366 3e-100
sp|P23966|MENB_BACSU Naphthoate synthase OS=Bacillus subtilis GN... 344 1e-093
sp|Q5HQC3|MENB_STAEQ Naphthoate synthase OS=Staphylococcus epide... 341 1e-092
sp|Q8CPQ4|MENB_STAES Naphthoate synthase OS=Staphylococcus epide... 341 1e-092
sp|Q4L549|MENB_STAHJ Naphthoate synthase OS=Staphylococcus haemo... 338 6e-092
sp|Q6GAG7|MENB_STAAS Naphthoate synthase OS=Staphylococcus aureu... 337 2e-091
sp|Q8NXA0|MENB_STAAW Naphthoate synthase OS=Staphylococcus aureu... 337 2e-091
sp|Q5HH38|MENB_STAAC Naphthoate synthase OS=Staphylococcus aureu... 336 2e-091
sp|Q6GI37|MENB_STAAR Naphthoate synthase OS=Staphylococcus aureu... 336 2e-091
sp|Q99V48|MENB_STAAM Naphthoate synthase OS=Staphylococcus aureu... 335 5e-091
sp|Q7A6A9|MENB_STAAN Naphthoate synthase OS=Staphylococcus aureu... 335 5e-091
sp|Q49WG8|MENB_STAS1 Naphthoate synthase OS=Staphylococcus sapro... 334 9e-091
sp|Q9TM10|MENB_CYACA Naphthoate synthase OS=Cyanidium caldarium ... 304 2e-081
sp|P64017|ECHA8_MYCBO Probable enoyl-CoA hydratase echA8 OS=Myco... 126 5e-028
sp|P64016|ECHA8_MYCTU Probable enoyl-CoA hydratase echA8 OS=Myco... 126 5e-028
sp|P52046|CRT_CLOAB 3-hydroxybutyryl-CoA dehydratase OS=Clostrid... 122 9e-027
sp|O07137|ECHA8_MYCLE Probable enoyl-CoA hydratase echA8 OS=Myco... 119 6e-026
>sp|Q9CLV5|MENB_PASMU Naphthoate synthase OS=Pasteurella multocida GN=menB PE=3
SV=1
Length = 285
Score = 371 bits (950), Expect = 1e-101
Identities = 183/265 (69%), Positives = 216/265 (81%), Gaps = 2/265 (0%)
Frame = +3
Query: 414 FVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKGTK 593
+ DI+Y K++ + IAKITINRPE RNAFRPQTVKE+++AF DAR D +GVI+LTG+G K
Sbjct: 22 YTDILYHKSL-DGIAKITINRPEVRNAFRPQTVKEMIQAFADARFDEQIGVIVLTGQGEK 80
Query: 594 AFCSGGDQALRTS-DGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMV 770
AFCSGGDQ +R GY D + V LNVLD Q IR PKPV+AMVAGYA+GGGH+LHM+
Sbjct: 81 AFCSGGDQKVRGDYGGYQDESGVHHLNVLDFQRDIRTCPKPVVAMVAGYAIGGGHVLHMI 140
Query: 771 CDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGL 950
CDLTIAADNAIFGQTGPKVGSFD G+G+S M+R+VG KKARE+WF+ R Y A EA +MGL
Sbjct: 141 CDLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKEALEMGL 200
Query: 951 INAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYGT 1130
+N VVP +LEKETV+WCRE+LRNSP A+R LKAALNA DG AGLQEL GNAT+LFY T
Sbjct: 201 VNTVVPYAELEKETVRWCREMLRNSPIALRCLKAALNADCDGQAGLQELAGNATMLFYMT 260
Query: 1131 EEGIEGRTAYMQRRPPDFSKFSRRP 1205
EEG EGR A+ ++R PDFSKF R P
Sbjct: 261 EEGQEGRNAFNEKRAPDFSKFKRNP 285
>sp|P44960|MENB_HAEIN Naphthoate synthase OS=Haemophilus influenzae GN=menB PE=3
SV=1
Length = 285
Score = 370 bits (948), Expect = 2e-101
Identities = 186/265 (70%), Positives = 214/265 (80%), Gaps = 2/265 (0%)
Frame = +3
Query: 414 FVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKGTK 593
+ DI Y K+ + IAKITINRPE RNAFRPQTVKE+M AF+DAR D ++GVI+LTG+G K
Sbjct: 22 YSDIRYHKST-DGIAKITINRPEVRNAFRPQTVKEMMTAFSDARFDENIGVIVLTGEGEK 80
Query: 594 AFCSGGDQALRTS-DGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMV 770
AFCSGGDQ +R GY D + V LNVLD Q IR PKPV+AMVAGYA+GGGH+LHM+
Sbjct: 81 AFCSGGDQKVRGDYGGYKDDSGVHHLNVLDFQRDIRSCPKPVVAMVAGYAIGGGHVLHML 140
Query: 771 CDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGL 950
CDLTIAA+NAIFGQTGPKVGSFD G+G+S M+RLVG KKARE+WF+ R Y A EA MGL
Sbjct: 141 CDLTIAAENAIFGQTGPKVGSFDGGWGASYMARLVGQKKAREIWFLCRQYNAQEALDMGL 200
Query: 951 INAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYGT 1130
+N VVP DLEKETV+WCRE+LRNSP AIR LKAALNA DG AGLQEL GNAT+LFY T
Sbjct: 201 VNTVVPYADLEKETVRWCREMLRNSPIAIRCLKAALNADCDGQAGLQELAGNATMLFYMT 260
Query: 1131 EEGIEGRTAYMQRRPPDFSKFSRRP 1205
EEG EGR A+ ++R PDFSKF R P
Sbjct: 261 EEGQEGRNAFNEKRAPDFSKFRRNP 285
>sp|P0ABU1|MENB_ECOL6 Naphthoate synthase OS=Escherichia coli O6 GN=menB PE=3
SV=1
Length = 285
Score = 366 bits (938), Expect = 3e-100
Identities = 184/265 (69%), Positives = 215/265 (81%), Gaps = 2/265 (0%)
Frame = +3
Query: 414 FVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKGTK 593
F DI YEK+ + IAKITINRP+ RNAFRP TVKE+++A DAR D+++GVIILTG G K
Sbjct: 22 FEDIRYEKST-DGIAKITINRPQVRNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDK 80
Query: 594 AFCSGGDQALRTS-DGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMV 770
AFCSGGDQ +R GY D + V LNVLD Q QIR PKPV+AMVAGY++GGGH+LHM+
Sbjct: 81 AFCSGGDQKVRGDYGGYKDDSGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMM 140
Query: 771 CDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGL 950
CDLTIAADNAIFGQTGPKVGSFD G+G+S M+R+VG KKARE+WF+ R Y A +A MGL
Sbjct: 141 CDLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGL 200
Query: 951 INAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYGT 1130
+N VVPL DLEKETV+WCRE+L+NSP A+R LKAALNA DG AGLQEL GNAT+LFY T
Sbjct: 201 VNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMT 260
Query: 1131 EEGIEGRTAYMQRRPPDFSKFSRRP 1205
EEG EGR A+ Q+R PDFSKF R P
Sbjct: 261 EEGQEGRNAFNQKRQPDFSKFKRNP 285
>sp|P0ABU0|MENB_ECOLI Naphthoate synthase OS=Escherichia coli (strain K12)
GN=menB PE=1 SV=1
Length = 285
Score = 366 bits (938), Expect = 3e-100
Identities = 184/265 (69%), Positives = 215/265 (81%), Gaps = 2/265 (0%)
Frame = +3
Query: 414 FVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKGTK 593
F DI YEK+ + IAKITINRP+ RNAFRP TVKE+++A DAR D+++GVIILTG G K
Sbjct: 22 FEDIRYEKST-DGIAKITINRPQVRNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDK 80
Query: 594 AFCSGGDQALRTS-DGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMV 770
AFCSGGDQ +R GY D + V LNVLD Q QIR PKPV+AMVAGY++GGGH+LHM+
Sbjct: 81 AFCSGGDQKVRGDYGGYKDDSGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMM 140
Query: 771 CDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGL 950
CDLTIAADNAIFGQTGPKVGSFD G+G+S M+R+VG KKARE+WF+ R Y A +A MGL
Sbjct: 141 CDLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGL 200
Query: 951 INAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYGT 1130
+N VVPL DLEKETV+WCRE+L+NSP A+R LKAALNA DG AGLQEL GNAT+LFY T
Sbjct: 201 VNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMT 260
Query: 1131 EEGIEGRTAYMQRRPPDFSKFSRRP 1205
EEG EGR A+ Q+R PDFSKF R P
Sbjct: 261 EEGQEGRNAFNQKRQPDFSKFKRNP 285
>sp|P23966|MENB_BACSU Naphthoate synthase OS=Bacillus subtilis GN=menB PE=3
SV=2
Length = 271
Score = 344 bits (881), Expect = 1e-093
Identities = 168/266 (63%), Positives = 207/266 (77%), Gaps = 2/266 (0%)
Frame = +3
Query: 408 KEFVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKG 587
+ + +I+YE G IAKITINRPE NAF P+TV E++ AF DARDD +VGVI+L G G
Sbjct: 8 RTYDEILYETYNG--IAKITINRPEVHNAFTPKTVAEMIDAFADARDDQNVGVIVLAGAG 65
Query: 588 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 767
KAFCSGGDQ +R GY + + RLNVLDLQ IR +PKPV+AMV+GYA+GGGH+LH+
Sbjct: 66 DKAFCSGGDQKVRGHGGYVGDDQIPRLNVLDLQRLIRVIPKPVVAMVSGYAIGGGHVLHI 125
Query: 768 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 947
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 126 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 185
Query: 948 LINAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1127
L+N VVPLE LE+ET+KWC E+L SPTA+R LKAA NA DG AG+Q+ G+ATLL+Y
Sbjct: 186 LVNTVVPLEQLEEETIKWCEEMLEKSPTALRFLKAAFNADTDGLAGIQQFAGDATLLYYT 245
Query: 1128 TEEGIEGRTAYMQRRPPDFSKFSRRP 1205
T+E EGR ++ ++R PDF +F R P
Sbjct: 246 TDEAKEGRDSFKEKRKPDFGQFPRFP 271
>sp|Q5HQC3|MENB_STAEQ Naphthoate synthase OS=Staphylococcus epidermidis (strain
ATCC 35984 / RP62A) GN=menB PE=3 SV=1
Length = 272
Score = 341 bits (873), Expect = 1e-092
Identities = 168/266 (63%), Positives = 212/266 (79%), Gaps = 2/266 (0%)
Frame = +3
Query: 408 KEFVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKG 587
+E+ +I YE E IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 9 REYDEIKYE--FFEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEG 66
Query: 588 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 767
KAFCSGGDQ R GY +D+ RLNVLDLQ IR +PKPVIAMV GYA+GGG++L++
Sbjct: 67 DKAFCSGGDQKKRGHGGYVGEDDIPRLNVLDLQRLIRVIPKPVIAMVRGYAIGGGNVLNV 126
Query: 768 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 947
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 127 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 186
Query: 948 LINAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1127
L+N VVPLE +E ETVKWC++I+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 187 LVNTVVPLEQVEDETVKWCKDIMQHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 246
Query: 1128 TEEGIEGRTAYMQRRPPDFSKFSRRP 1205
T+E EGR A+ ++R PDF +F + P
Sbjct: 247 TDEAKEGRDAFKEKRNPDFDQFPKFP 272
>sp|Q8CPQ4|MENB_STAES Naphthoate synthase OS=Staphylococcus epidermidis (strain
ATCC 12228) GN=menB PE=3 SV=1
Length = 272
Score = 341 bits (873), Expect = 1e-092
Identities = 168/266 (63%), Positives = 212/266 (79%), Gaps = 2/266 (0%)
Frame = +3
Query: 408 KEFVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKG 587
+E+ +I YE E IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 9 REYDEIKYE--FFEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEG 66
Query: 588 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 767
KAFCSGGDQ R GY +D+ RLNVLDLQ IR +PKPVIAMV GYA+GGG++L++
Sbjct: 67 DKAFCSGGDQKKRGHGGYVGEDDIPRLNVLDLQRLIRVIPKPVIAMVRGYAIGGGNVLNV 126
Query: 768 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 947
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 127 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 186
Query: 948 LINAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1127
L+N VVPLE +E ETVKWC++I+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 187 LVNTVVPLEQVEDETVKWCKDIMQHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 246
Query: 1128 TEEGIEGRTAYMQRRPPDFSKFSRRP 1205
T+E EGR A+ ++R PDF +F + P
Sbjct: 247 TDEAKEGRDAFKEKRNPDFDQFPKFP 272
>sp|Q4L549|MENB_STAHJ Naphthoate synthase OS=Staphylococcus haemolyticus (strain
JCSC1435) GN=menB PE=3 SV=1
Length = 272
Score = 338 bits (866), Expect = 6e-092
Identities = 166/266 (62%), Positives = 211/266 (79%), Gaps = 2/266 (0%)
Frame = +3
Query: 408 KEFVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKG 587
+E+ +I YE E IAK+TINRPE RNAF P+TV E++ AF+ ARDD ++ VIILTG+G
Sbjct: 9 REYDEIKYE--FYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNISVIILTGEG 66
Query: 588 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 767
KAFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYA+GGG++L++
Sbjct: 67 DKAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRVIPKPVIAMVRGYAIGGGNVLNV 126
Query: 768 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 947
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 127 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 186
Query: 948 LINAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1127
L+N VVPL+ +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 187 LVNTVVPLDQIEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 246
Query: 1128 TEEGIEGRTAYMQRRPPDFSKFSRRP 1205
T+E EGR A+ ++R PDF +F + P
Sbjct: 247 TDEAKEGRDAFKEKRDPDFDQFPKFP 272
>sp|Q6GAG7|MENB_STAAS Naphthoate synthase OS=Staphylococcus aureus (strain
MSSA476) GN=menB PE=3 SV=1
Length = 273
Score = 337 bits (862), Expect = 2e-091
Identities = 167/266 (62%), Positives = 210/266 (78%), Gaps = 2/266 (0%)
Frame = +3
Query: 408 KEFVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKG 587
+E+ +I YE E IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 10 REYDEIKYE--FYEGIAKVTINRPEVRNAFTPKTVSEMIDAFSRARDDQNVSVIVLTGEG 67
Query: 588 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 767
AFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYAVGGG++L++
Sbjct: 68 DLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNV 127
Query: 768 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 947
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 128 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187
Query: 948 LINAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1127
L+N VVPLE +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 188 LVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 247
Query: 1128 TEEGIEGRTAYMQRRPPDFSKFSRRP 1205
T+E EGR A+ ++R PDF +F + P
Sbjct: 248 TDEAKEGRDAFKEKRDPDFDQFPKFP 273
>sp|Q8NXA0|MENB_STAAW Naphthoate synthase OS=Staphylococcus aureus (strain MW2)
GN=menB PE=3 SV=1
Length = 273
Score = 337 bits (862), Expect = 2e-091
Identities = 167/266 (62%), Positives = 210/266 (78%), Gaps = 2/266 (0%)
Frame = +3
Query: 408 KEFVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKG 587
+E+ +I YE E IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 10 REYDEIKYE--FYEGIAKVTINRPEVRNAFTPKTVSEMIDAFSRARDDQNVSVIVLTGEG 67
Query: 588 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 767
AFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYAVGGG++L++
Sbjct: 68 DLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNV 127
Query: 768 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 947
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 128 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187
Query: 948 LINAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1127
L+N VVPLE +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 188 LVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 247
Query: 1128 TEEGIEGRTAYMQRRPPDFSKFSRRP 1205
T+E EGR A+ ++R PDF +F + P
Sbjct: 248 TDEAKEGRDAFKEKRDPDFDQFPKFP 273
>sp|Q5HH38|MENB_STAAC Naphthoate synthase OS=Staphylococcus aureus (strain COL)
GN=menB PE=1 SV=1
Length = 273
Score = 336 bits (861), Expect = 2e-091
Identities = 167/266 (62%), Positives = 210/266 (78%), Gaps = 2/266 (0%)
Frame = +3
Query: 408 KEFVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKG 587
+E+ +I YE E IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 10 REYDEIKYE--FYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEG 67
Query: 588 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 767
AFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYAVGGG++L++
Sbjct: 68 DLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNV 127
Query: 768 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 947
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 128 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187
Query: 948 LINAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1127
L+N VVPLE +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 188 LVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 247
Query: 1128 TEEGIEGRTAYMQRRPPDFSKFSRRP 1205
T+E EGR A+ ++R PDF +F + P
Sbjct: 248 TDEAKEGRDAFKEKRDPDFDQFPKFP 273
>sp|Q6GI37|MENB_STAAR Naphthoate synthase OS=Staphylococcus aureus (strain
MRSA252) GN=menB PE=3 SV=1
Length = 273
Score = 336 bits (861), Expect = 2e-091
Identities = 167/266 (62%), Positives = 210/266 (78%), Gaps = 2/266 (0%)
Frame = +3
Query: 408 KEFVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKG 587
+E+ +I YE E IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 10 REYDEIKYE--FYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEG 67
Query: 588 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 767
AFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYAVGGG++L++
Sbjct: 68 DLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNV 127
Query: 768 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 947
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 128 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187
Query: 948 LINAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1127
L+N VVPLE +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 188 LVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 247
Query: 1128 TEEGIEGRTAYMQRRPPDFSKFSRRP 1205
T+E EGR A+ ++R PDF +F + P
Sbjct: 248 TDEAKEGRDAFKEKRDPDFDQFPKFP 273
>sp|Q99V48|MENB_STAAM Naphthoate synthase OS=Staphylococcus aureus (strain Mu50
/ ATCC 700699) GN=menB PE=1 SV=1
Length = 273
Score = 335 bits (858), Expect = 5e-091
Identities = 166/266 (62%), Positives = 210/266 (78%), Gaps = 2/266 (0%)
Frame = +3
Query: 408 KEFVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKG 587
+E+ +I YE E IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 10 REYDEIKYE--FYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEG 67
Query: 588 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 767
AFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYAVGGG++L++
Sbjct: 68 DLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNV 127
Query: 768 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 947
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 128 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187
Query: 948 LINAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1127
L+N VVPL+ +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 188 LVNTVVPLDKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 247
Query: 1128 TEEGIEGRTAYMQRRPPDFSKFSRRP 1205
T+E EGR A+ ++R PDF +F + P
Sbjct: 248 TDEAKEGRDAFKEKRDPDFDQFPKFP 273
>sp|Q7A6A9|MENB_STAAN Naphthoate synthase OS=Staphylococcus aureus (strain N315)
GN=menB PE=1 SV=1
Length = 273
Score = 335 bits (858), Expect = 5e-091
Identities = 166/266 (62%), Positives = 210/266 (78%), Gaps = 2/266 (0%)
Frame = +3
Query: 408 KEFVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKG 587
+E+ +I YE E IAK+TINRPE RNAF P+TV E++ AF+ ARDD +V VI+LTG+G
Sbjct: 10 REYDEIKYE--FYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEG 67
Query: 588 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 767
AFCSGGDQ R GY + + RLNVLDLQ IR +PKPVIAMV GYAVGGG++L++
Sbjct: 68 DLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNV 127
Query: 768 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 947
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 128 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187
Query: 948 LINAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1127
L+N VVPL+ +E ETV+WC+EI+++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 188 LVNTVVPLDKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 247
Query: 1128 TEEGIEGRTAYMQRRPPDFSKFSRRP 1205
T+E EGR A+ ++R PDF +F + P
Sbjct: 248 TDEAKEGRDAFKEKRDPDFDQFPKFP 273
>sp|Q49WG8|MENB_STAS1 Naphthoate synthase OS=Staphylococcus saprophyticus subsp.
saprophyticus (strain ATCC 15305 / DSM 20229) GN=menB PE=3 SV=1
Length = 272
Score = 334 bits (856), Expect = 9e-091
Identities = 163/266 (61%), Positives = 210/266 (78%), Gaps = 2/266 (0%)
Frame = +3
Query: 408 KEFVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKG 587
+E+ +I YE + + IAK+TINRPE RNAF P TV+E++ AF ARDD + VIILTG+G
Sbjct: 9 REYKEIKYE--LYDGIAKVTINRPEVRNAFTPNTVQEMIDAFTRARDDQRISVIILTGEG 66
Query: 588 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 767
KAFCSGGDQ +R GY + + RLNVLDLQ IR +PKPV+AMV GYA+GGG++L++
Sbjct: 67 DKAFCSGGDQKVRGHGGYVGDDQIPRLNVLDLQRLIRVIPKPVVAMVRGYAIGGGNVLNV 126
Query: 768 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 947
VCDLTIAADNAIFGQTGPKVGSFDAGYGS ++R+VG KKARE+W++ R Y A EA MG
Sbjct: 127 VCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 186
Query: 948 LINAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1127
L+N VVPL+ +E ETV+WC+E+ ++SPTA+R LKAA+NA DG AGLQ++ G+ATLL+Y
Sbjct: 187 LVNTVVPLDQVEDETVQWCQEMKQHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT 246
Query: 1128 TEEGIEGRTAYMQRRPPDFSKFSRRP 1205
T+E EGR A+ ++R PDF +F + P
Sbjct: 247 TDEAKEGRDAFKEKRDPDFDQFPKFP 272
>sp|Q9TM10|MENB_CYACA Naphthoate synthase OS=Cyanidium caldarium GN=menB PE=3
SV=1
Length = 268
Score = 304 bits (776), Expect = 2e-081
Identities = 150/263 (57%), Positives = 199/263 (75%), Gaps = 2/263 (0%)
Frame = +3
Query: 408 KEFVDIIYEKAVGEDIAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKG 587
K+F+DI Y K + I++I I+RP+ NAFRP+T+ E++ AF D+R+D+S+GV+IL+G G
Sbjct: 7 KDFIDIKYIKQ--DQISEIIISRPQVLNAFRPRTINEIIAAFYDSREDSSIGVVILSGHG 64
Query: 588 TKAFCSGGDQALRTSDGYADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHM 767
++AFC GGDQ +R+ GY D LNVL+LQ IR PKPVIA V+GYAVGGG IL+M
Sbjct: 65 SRAFCVGGDQKIRSKTGYIDEKGRSSLNVLELQRIIRTFPKPVIAKVSGYAVGGGQILNM 124
Query: 768 VCDLTIAADNAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMG 947
+CDLTIA++NA+ GQ+GPKVGSFDAGYGS+ M+R++G KKARE+WF Y A EA KMG
Sbjct: 125 MCDLTIASENAVLGQSGPKVGSFDAGYGSAYMARIIGQKKARELWFTCYQYDAFEAYKMG 184
Query: 948 LINAVVPLEDLEKETVKWCREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG 1127
L+N VV +EDL+ +K +IL SP AIR LK++LNA DG +GLQEL G +T+LFY
Sbjct: 185 LVNWVVKIEDLDSYAIKLATDILNKSPLAIRFLKSSLNADCDGQSGLQELAGYSTMLFYM 244
Query: 1128 TEEGIEGRTAYMQRRPPDFSKFS 1196
+ EG EG A+++ R PDFSKF+
Sbjct: 245 SAEGQEGHRAFLENREPDFSKFN 267
>sp|P64017|ECHA8_MYCBO Probable enoyl-CoA hydratase echA8 OS=Mycobacterium bovis
GN=echA8 PE=3 SV=1
Length = 257
Score = 126 bits (315), Expect = 5e-028
Identities = 86/247 (34%), Positives = 127/247 (51%), Gaps = 13/247 (5%)
Frame = +3
Query: 462 ITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKGTKAFCSGGDQALRTSDGY 641
IT+NRP+ NA Q + E+ A + DD +G II+TG KAF +G D +
Sbjct: 17 ITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITG-SAKAFAAGADIKEMADLTF 75
Query: 642 ADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAIFGQTGP 821
AD +R P IA VAGYA+GGG L M+CD+ IAAD A FGQ
Sbjct: 76 ADAFTADFFATWGKLAAVR---TPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEI 132
Query: 822 KVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGLINAVVPLEDLEKETVKW 1001
K+G GS ++R +G KA ++ R A+EA++ GL++ VVP +DL E
Sbjct: 133 KLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARAT 192
Query: 1002 CREILRNSPTAIRVLKAALN-----AVDDGHAGLQELGGNATLLFYGTEEGIEGRTAYMQ 1166
I + S +A R+ K A+N ++ +G + L +A + TE+ EG A+++
Sbjct: 193 ATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSA----FATEDQSEGMAAFIE 248
Query: 1167 RRPPDFS 1187
+R P F+
Sbjct: 249 KRAPQFT 255
>sp|P64016|ECHA8_MYCTU Probable enoyl-CoA hydratase echA8 OS=Mycobacterium
tuberculosis GN=echA8 PE=1 SV=1
Length = 257
Score = 126 bits (315), Expect = 5e-028
Identities = 86/247 (34%), Positives = 127/247 (51%), Gaps = 13/247 (5%)
Frame = +3
Query: 462 ITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKGTKAFCSGGDQALRTSDGY 641
IT+NRP+ NA Q + E+ A + DD +G II+TG KAF +G D +
Sbjct: 17 ITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITG-SAKAFAAGADIKEMADLTF 75
Query: 642 ADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAIFGQTGP 821
AD +R P IA VAGYA+GGG L M+CD+ IAAD A FGQ
Sbjct: 76 ADAFTADFFATWGKLAAVR---TPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEI 132
Query: 822 KVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGLINAVVPLEDLEKETVKW 1001
K+G GS ++R +G KA ++ R A+EA++ GL++ VVP +DL E
Sbjct: 133 KLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARAT 192
Query: 1002 CREILRNSPTAIRVLKAALN-----AVDDGHAGLQELGGNATLLFYGTEEGIEGRTAYMQ 1166
I + S +A R+ K A+N ++ +G + L +A + TE+ EG A+++
Sbjct: 193 ATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSA----FATEDQSEGMAAFIE 248
Query: 1167 RRPPDFS 1187
+R P F+
Sbjct: 249 KRAPQFT 255
>sp|P52046|CRT_CLOAB 3-hydroxybutyryl-CoA dehydratase OS=Clostridium
acetobutylicum GN=crt PE=3 SV=1
Length = 261
Score = 122 bits (304), Expect = 9e-027
Identities = 82/251 (32%), Positives = 133/251 (52%), Gaps = 22/251 (8%)
Frame = +3
Query: 453 IAKITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKGTKAFCSGGD----QA 620
+A +TINRP+ NA T+KE+ + +D+ V +ILTG G K+F +G D +
Sbjct: 14 VAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSFVAGADISEMKE 73
Query: 621 LRTSDGYADPNDVGRLNVLDLQV--QIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAAD 794
+ T +G + +L +V ++ L KPVIA V G+A+GGG + M CD+ IA+
Sbjct: 74 MNTIEG-------RKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSCDIRIASS 126
Query: 795 NAIFGQTGPKVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGLINAVVPLE 974
NA FGQ +G G+ +SRLVG A+++ F + A EA ++GL+N VV
Sbjct: 127 NARFGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLVNKVVEPS 186
Query: 975 DLEKETVKWCREILRNSPTAIRVLKAALNA-----VDDGHAGLQELGGNATLLFYGTEEG 1139
+L + +I+ N+P A+++ K A+N +D A E G + TE+
Sbjct: 187 ELMNTAKEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFESEAFGEC----FSTEDQ 242
Query: 1140 IEGRTAYMQRR 1172
+ TA++++R
Sbjct: 243 KDAMTAFIEKR 253
>sp|O07137|ECHA8_MYCLE Probable enoyl-CoA hydratase echA8 OS=Mycobacterium
leprae GN=echA8 PE=3 SV=1
Length = 257
Score = 119 bits (297), Expect = 6e-026
Identities = 85/245 (34%), Positives = 125/245 (51%), Gaps = 9/245 (3%)
Frame = +3
Query: 462 ITINRPERRNAFRPQTVKELMRAFNDARDDNSVGVIILTGKGTKAFCSGGDQALRTSDGY 641
IT+NRP+ NA Q + E+ A + D VG I++TG K F +G D S +
Sbjct: 17 ITLNRPQALNALNSQMMNEITNAAKELDIDPDVGAILITG-SPKVFAAGADIKEMASLTF 75
Query: 642 ADPNDVGRLNVLDLQVQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAIFGQTGP 821
D D + +R P+IA VAGYA+GGG L M+CDL IAAD A FGQ
Sbjct: 76 TDAFDADFFSAWGKLAAVR---TPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEI 132
Query: 822 KVGSFDAGYGSSIMSRLVGPKKAREMWFMTRFYTASEADKMGLINAVVPLEDLEKETVKW 1001
K+G GS ++R +G KA ++ R A+EA++ GL++ VV +DL E
Sbjct: 133 KLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAV 192
Query: 1002 CREILRNSPTAIRVLKAALNAVDDGHAGLQELGGNATLLFYG---TEEGIEGRTAYMQRR 1172
I + S +A R+ K A+N + L E + LF+ T++ EG A++++R
Sbjct: 193 ATTISQMSRSATRMAKEAVNR--SFESTLAEGLLHERRLFHSTFVTDDQSEGMAAFIEKR 250
Query: 1173 PPDFS 1187
P F+
Sbjct: 251 APQFT 255
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,281,224,270
Number of Sequences: 518415
Number of Extensions: 55281224270
Number of Successful Extensions: 373770181
Number of sequences better than 0.0: 0
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