BLASTX 7.6.2
Query= UN13821 /QuerySize=1632
(1631 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=R... 89 6e-017
sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN... 89 6e-017
sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN... 89 1e-016
sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo... 87 3e-016
sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabido... 87 4e-016
sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 85 2e-015
sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus ... 84 2e-015
sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 84 3e-015
sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 84 3e-015
sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabido... 82 8e-015
sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Dani... 82 1e-014
sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos ... 77 4e-013
sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo... 77 4e-013
sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus... 76 7e-013
sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus ... 75 1e-012
sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Dros... 63 6e-009
sp|Q9C1X4|YKW3_SCHPO Uncharacterized RING finger protein P32A8.0... 61 2e-008
sp|Q8VEM1|GOLI_MOUSE Goliath homolog OS=Mus musculus GN=Rnf130 P... 56 8e-007
sp|Q6Y290|GOLI_RAT Goliath homolog OS=Rattus norvegicus GN=Rnf13... 56 8e-007
sp|Q86XS8|GOLI_HUMAN Goliath homolog OS=Homo sapiens GN=RNF130 P... 55 1e-006
>sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=RNF126 PE=2
SV=1
Length = 313
Score = 89 bits (220), Expect = 6e-017
Identities = 49/106 (46%), Positives = 61/106 (57%), Gaps = 7/106 (6%)
Frame = +3
Query: 777 DYFIGP-GLDLLLQHLAENDSNRQGTPPARKEAVEALPTVKITE----PSLQCSVCLDDF 941
DY G GLD ++ L N G PPA KE ++ALPTV +TE L+C VC DD+
Sbjct: 181 DYAWGANGLDAIITQLL-NQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDY 239
Query: 942 ERGVDEAKEMPCKHKFHVKCIVPWLELHNSFPVCRFELPSGNDDGD 1079
G + +++PC H FH CIVPWLE H+S PVCR L N D
Sbjct: 240 GLG-EHVRQLPCNHLFHDGCIVPWLEQHDSCPVCRKSLTGQNTATD 284
>sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN=RNF126 PE=1
SV=1
Length = 326
Score = 89 bits (220), Expect = 6e-017
Identities = 48/102 (47%), Positives = 60/102 (58%), Gaps = 7/102 (6%)
Frame = +3
Query: 777 DYFIGP-GLDLLLQHLAENDSNRQGTPPARKEAVEALPTVKITE----PSLQCSVCLDDF 941
DY G GLD ++ L N G PPA KE ++ALPTV +TE L+C VC DD+
Sbjct: 178 DYAWGANGLDAIITQLL-NQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDY 236
Query: 942 ERGVDEAKEMPCKHKFHVKCIVPWLELHNSFPVCRFELPSGN 1067
G + +++PC H FH CIVPWLE H+S PVCR L N
Sbjct: 237 ALG-ERVRQLPCNHLFHDGCIVPWLEQHDSCPVCRKSLTGQN 277
>sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN=Rnf126 PE=1
SV=1
Length = 313
Score = 89 bits (218), Expect = 1e-016
Identities = 47/102 (46%), Positives = 60/102 (58%), Gaps = 7/102 (6%)
Frame = +3
Query: 777 DYFIGP-GLDLLLQHLAENDSNRQGTPPARKEAVEALPTVKITE----PSLQCSVCLDDF 941
DY G GLD ++ L N G PPA KE ++ALPTV +TE L+C VC +D+
Sbjct: 180 DYAWGANGLDTIITQLL-NQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKEDY 238
Query: 942 ERGVDEAKEMPCKHKFHVKCIVPWLELHNSFPVCRFELPSGN 1067
G + +++PC H FH CIVPWLE H+S PVCR L N
Sbjct: 239 ALG-ESVRQLPCNHLFHDSCIVPWLEQHDSCPVCRKSLTGQN 279
>sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo sapiens
GN=RNF115 PE=1 SV=2
Length = 304
Score = 87 bits (214), Expect = 3e-016
Identities = 51/129 (39%), Positives = 70/129 (54%), Gaps = 8/129 (6%)
Frame = +3
Query: 774 GDYFIG-PGLDLLLQHLAENDSNRQGTPPARKEAVEALPTVKITEP----SLQCSVCLDD 938
GDY G GLD ++ L N G PPA KE + +LPTV +T+ L+C VC +D
Sbjct: 176 GDYAWGQTGLDAIVTQLLGQLEN-TGPPPADKEKITSLPTVTVTQEQVDMGLECPVCKED 234
Query: 939 FERGVDEAKEMPCKHKFHVKCIVPWLELHNSFPVCRFELPSGNDDGDGESKVESGGGART 1118
+ +E +++PC H FH CIVPWLELH++ PVCR L +G D E+ R
Sbjct: 235 Y-TVEEEVRQLPCNHFFHSSCIVPWLELHDTCPVCRKSL-NGEDSTRQSQSTEASASNRF 292
Query: 1119 RSVPESSDR 1145
+ + DR
Sbjct: 293 SNDSQLHDR 301
>sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabidopsis thaliana
GN=CIP8 PE=1 SV=1
Length = 334
Score = 87 bits (213), Expect = 4e-016
Identities = 50/123 (40%), Positives = 71/123 (57%), Gaps = 15/123 (12%)
Frame = +3
Query: 795 GLDLLLQHLAEND----SNRQGTPPARKEAVEALPTVKIT----EPSLQCSVCLDDFERG 950
G + LLQ+LAE D R+G PPA K A+EAL T +++ E + C+VC D G
Sbjct: 208 GYEALLQNLAEGDGGGGGGRRGAPPAAKSAIEALETFEVSSSEGEMVMVCAVCKDGMVMG 267
Query: 951 VDEAKEMPCKHKFHVKCIVPWLELHNSFPVCRFELPSGNDDGDGESKVESGGGARTRSVP 1130
+ K++PC H +H CIVPWL NS PVCRF+L + + + + E K RT +V
Sbjct: 268 -ETGKKLPCGHCYHGDCIVPWLGTRNSCPVCRFQLETDDAEYEEERK------KRTSTVS 320
Query: 1131 ESS 1139
+S+
Sbjct: 321 DSA 323
>sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126
PE=2 SV=1
Length = 311
Score = 85 bits (208), Expect = 2e-015
Identities = 44/102 (43%), Positives = 60/102 (58%), Gaps = 7/102 (6%)
Frame = +3
Query: 777 DYFIGP-GLDLLLQHLAENDSNRQGTPPARKEAVEALPTVKITE----PSLQCSVCLDDF 941
DY G GLD ++ L N G PPA E ++ALPT++ITE L+C VC +D+
Sbjct: 176 DYAWGANGLDTIITQLL-NQFENTGPPPADTEKIQALPTIQITEEHVGSGLECPVCKEDY 234
Query: 942 ERGVDEAKEMPCKHKFHVKCIVPWLELHNSFPVCRFELPSGN 1067
G + +++PC H FH CI+PWLE H++ PVCR L N
Sbjct: 235 TVG-ESVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSLSGQN 275
>sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus musculus
GN=Rnf115 PE=1 SV=1
Length = 305
Score = 84 bits (207), Expect = 2e-015
Identities = 50/129 (38%), Positives = 70/129 (54%), Gaps = 8/129 (6%)
Frame = +3
Query: 774 GDYFIG-PGLDLLLQHLAENDSNRQGTPPARKEAVEALPTVKITE----PSLQCSVCLDD 938
GDY G GLD ++ L N G PPA KE + +LPTV +T+ L+C VC +D
Sbjct: 177 GDYAWGQTGLDAIVTQLLGQLEN-TGPPPADKEKITSLPTVTVTQEQVNTGLECPVCKED 235
Query: 939 FERGVDEAKEMPCKHKFHVKCIVPWLELHNSFPVCRFELPSGNDDGDGESKVESGGGART 1118
+ ++ +++PC H FH CIVPWLELH++ PVCR L +G D E+ R
Sbjct: 236 Y-TVEEKVRQLPCNHFFHSSCIVPWLELHDTCPVCRKSL-NGEDSTRQTQSSEASASNRF 293
Query: 1119 RSVPESSDR 1145
+ + DR
Sbjct: 294 SNDSQLHDR 302
>sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-a
PE=2 SV=1
Length = 312
Score = 84 bits (205), Expect = 3e-015
Identities = 44/102 (43%), Positives = 60/102 (58%), Gaps = 7/102 (6%)
Frame = +3
Query: 777 DYFIGP-GLDLLLQHLAENDSNRQGTPPARKEAVEALPTVKITE----PSLQCSVCLDDF 941
DY G GLD ++ L N G PPA E ++ALPT++ITE L+C VC +D+
Sbjct: 177 DYAWGANGLDTIITQLL-NQFENTGPPPADNEKIQALPTIQITEEHVGSGLECPVCKEDY 235
Query: 942 ERGVDEAKEMPCKHKFHVKCIVPWLELHNSFPVCRFELPSGN 1067
G + +++PC H FH CI+PWLE H++ PVCR L N
Sbjct: 236 TVG-ECVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSLSGQN 276
>sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-b
PE=2 SV=1
Length = 312
Score = 84 bits (205), Expect = 3e-015
Identities = 43/102 (42%), Positives = 60/102 (58%), Gaps = 7/102 (6%)
Frame = +3
Query: 777 DYFIGP-GLDLLLQHLAENDSNRQGTPPARKEAVEALPTVKITEP----SLQCSVCLDDF 941
DY G GLD ++ L N G PPA + ++ALPT++ITE L+C VC +D+
Sbjct: 177 DYAWGANGLDTIITQLL-NQFENTGPPPADTDKIQALPTIQITEEHVGFGLECPVCKEDY 235
Query: 942 ERGVDEAKEMPCKHKFHVKCIVPWLELHNSFPVCRFELPSGN 1067
G + +++PC H FH CI+PWLE H++ PVCR L N
Sbjct: 236 TVG-ESVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSLSGQN 276
>sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabidopsis thaliana
GN=AIP2 PE=1 SV=1
Length = 310
Score = 82 bits (202), Expect = 8e-015
Identities = 40/96 (41%), Positives = 57/96 (59%), Gaps = 9/96 (9%)
Frame = +3
Query: 795 GLDLLLQHLAENDSNRQGTPPARKEAVEALPTVKITEPSL-------QCSVCLDDFERGV 953
GLD+++ + + D PPA KE VE LP + TE L +C +C ++ G
Sbjct: 183 GLDMIIPDILD-DGGPPRAPPASKEVVEKLPVIIFTEELLKKFGAEAECCICKENLVIG- 240
Query: 954 DEAKEMPCKHKFHVKCIVPWLELHNSFPVCRFELPS 1061
D+ +E+PCKH FH C+ PWL+ HNS P+CR ELP+
Sbjct: 241 DKMQELPCKHTFHPPCLKPWLDEHNSCPICRHELPT 276
>sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Danio rerio
GN=rnf181 PE=2 SV=2
Length = 156
Score = 82 bits (200), Expect = 1e-014
Identities = 42/97 (43%), Positives = 59/97 (60%), Gaps = 5/97 (5%)
Frame = +3
Query: 795 GLDLLLQHLAENDSNRQGTPPARKEAVEALPTVKIT----EPSLQCSVCLDDFERGVDEA 962
GLD+ +D +++ PPA K V++LP V I+ + ++C VCL +FE +
Sbjct: 34 GLDIDSGSFDLSDWDQRLPPPAAKAVVQSLPVVIISPEQADKGVKCPVCLLEFEE-QESV 92
Query: 963 KEMPCKHKFHVKCIVPWLELHNSFPVCRFELPSGNDD 1073
+EMPCKH FH CI+PWL NS P+CR ELP+ N D
Sbjct: 93 REMPCKHLFHTGCILPWLNKTNSCPLCRLELPTDNAD 129
>sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos taurus
GN=RNF181 PE=2 SV=1
Length = 153
Score = 77 bits (187), Expect = 4e-013
Identities = 38/75 (50%), Positives = 49/75 (65%), Gaps = 3/75 (4%)
Frame = +3
Query: 852 PPARKEAVEALP--TVKITEPSLQCSVCLDDFERGVDEAKEMPCKHKFHVKCIVPWLELH 1025
PPA K AVE LP ++ ++ L+C VCL +FE + A EMPC H FH CI+PWL
Sbjct: 52 PPAAKTAVENLPRTVIRGSQAELKCPVCLLEFEE-EETAIEMPCHHLFHSNCILPWLSKT 110
Query: 1026 NSFPVCRFELPSGND 1070
NS P+CR ELP+ +D
Sbjct: 111 NSCPLCRHELPTDDD 125
>sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo sapiens
GN=RNF181 PE=1 SV=1
Length = 153
Score = 77 bits (187), Expect = 4e-013
Identities = 37/75 (49%), Positives = 49/75 (65%), Gaps = 3/75 (4%)
Frame = +3
Query: 852 PPARKEAVEALP--TVKITEPSLQCSVCLDDFERGVDEAKEMPCKHKFHVKCIVPWLELH 1025
PPA K VE LP ++ ++ L+C VCL +FE + A EMPC H FH CI+PWL
Sbjct: 52 PPAAKTVVENLPRTVIRGSQAELKCPVCLLEFEE-EETAIEMPCHHLFHSSCILPWLSKT 110
Query: 1026 NSFPVCRFELPSGND 1070
NS P+CR+ELP+ +D
Sbjct: 111 NSCPLCRYELPTDDD 125
>sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus norvegicus
GN=Rnf181 PE=1 SV=1
Length = 165
Score = 76 bits (185), Expect = 7e-013
Identities = 37/82 (45%), Positives = 50/82 (60%), Gaps = 3/82 (3%)
Frame = +3
Query: 852 PPARKEAVEALP--TVKITEPSLQCSVCLDDFERGVDEAKEMPCKHKFHVKCIVPWLELH 1025
PPA K VE+LP ++ ++ L+C VCL +FE + EMPC H FH CI+PWL
Sbjct: 64 PPAAKAVVESLPRTVIRSSKAELKCPVCLLEFEE-EETVIEMPCHHLFHSNCILPWLSKT 122
Query: 1026 NSFPVCRFELPSGNDDGDGESK 1091
NS P+CR ELP+ +D + K
Sbjct: 123 NSCPLCRHELPTDDDSYEEHKK 144
>sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus musculus
GN=Rnf181 PE=2 SV=1
Length = 165
Score = 75 bits (183), Expect = 1e-012
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 3/82 (3%)
Frame = +3
Query: 852 PPARKEAVEALPTVKIT--EPSLQCSVCLDDFERGVDEAKEMPCKHKFHVKCIVPWLELH 1025
PPA K VE+LP I+ + L+C VCL +FE + EMPC H FH CI+PWL
Sbjct: 64 PPAAKAVVESLPRTVISSAKADLKCPVCLLEFE-AEETVIEMPCHHLFHSNCILPWLSKT 122
Query: 1026 NSFPVCRFELPSGNDDGDGESK 1091
NS P+CR ELP+ +D + K
Sbjct: 123 NSCPLCRHELPTDDDSYEEHKK 144
>sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Drosophila
melanogaster GN=CG7694 PE=2 SV=1
Length = 147
Score = 63 bits (151), Expect = 6e-009
Identities = 31/72 (43%), Positives = 45/72 (62%), Gaps = 5/72 (6%)
Frame = +3
Query: 852 PPARKEAVEALPTVKITEP----SLQCSVCLDDFERGVDEAKEMPCKHKFHVKCIVPWLE 1019
P A K A+ LP +I + L+CSVC + E G + + +PCKH+FH +CI+ WL+
Sbjct: 44 PEASKRAILELPVHEIVKSDEGGDLECSVCKEPAEEG-QKYRILPCKHEFHEECILLWLK 102
Query: 1020 LHNSFPVCRFEL 1055
NS P+CR+EL
Sbjct: 103 KTNSCPLCRYEL 114
>sp|Q9C1X4|YKW3_SCHPO Uncharacterized RING finger protein P32A8.03c
OS=Schizosaccharomyces pombe GN=SPAP32A8.03c PE=2 SV=1
Length = 513
Score = 61 bits (147), Expect = 2e-008
Identities = 31/116 (26%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Frame = +3
Query: 774 GDYFIGP-GLDLLLQHLAENDSNRQGTPPARKEAVEAL----PTVKITEPSLQCSVCLDD 938
GDY G GLD ++ L E PA ++ + + P ++ + +C++C++
Sbjct: 343 GDYAWGARGLDDIISQLMEQAQGHNAPAPAPEDVIAKMKVQKPPKELIDEEGECTICMEM 402
Query: 939 FERGVDEAKEMPCKHKFHVKCIVPWLELHNSFPVCRFELPSGNDDGDGESKVESGG 1106
F+ D+ ++PCKH FH CI PWL ++ + +CR + + + S + G
Sbjct: 403 FKIN-DDVIQLPCKHYFHENCIKPWLRVNGTCAICRAPVDPNSQQRNNTSTDSANG 457
>sp|Q8VEM1|GOLI_MOUSE Goliath homolog OS=Mus musculus GN=Rnf130 PE=2 SV=1
Length = 419
Score = 56 bits (133), Expect = 8e-007
Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 8/89 (8%)
Frame = +3
Query: 810 LQHLAENDSNRQGTPPARKEAVEALPT------VKITEPSL-QCSVCLDDFERGVDEAKE 968
+++ D N++ A K+A+ L T K T+P C+VC++ +++ D +
Sbjct: 221 IRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQN-DVVRV 279
Query: 969 MPCKHKFHVKCIVPWLELHNSFPVCRFEL 1055
+PCKH FH C+ PWL H + P+C+ +
Sbjct: 280 LPCKHVFHKSCVDPWLSEHCTCPMCKLNI 308
>sp|Q6Y290|GOLI_RAT Goliath homolog OS=Rattus norvegicus GN=Rnf130 PE=1 SV=1
Length = 419
Score = 56 bits (133), Expect = 8e-007
Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 8/89 (8%)
Frame = +3
Query: 810 LQHLAENDSNRQGTPPARKEAVEALPT------VKITEPSL-QCSVCLDDFERGVDEAKE 968
+++ D N++ A K+A+ L T K T+P C+VC++ +++ D +
Sbjct: 221 IRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQN-DVVRV 279
Query: 969 MPCKHKFHVKCIVPWLELHNSFPVCRFEL 1055
+PCKH FH C+ PWL H + P+C+ +
Sbjct: 280 LPCKHVFHKSCVDPWLSEHCTCPMCKLNI 308
>sp|Q86XS8|GOLI_HUMAN Goliath homolog OS=Homo sapiens GN=RNF130 PE=1 SV=1
Length = 419
Score = 55 bits (132), Expect = 1e-006
Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 8/89 (8%)
Frame = +3
Query: 810 LQHLAENDSNRQGTPPARKEAVEALPT------VKITEPSL-QCSVCLDDFERGVDEAKE 968
+++ D N++ A K+A+ L T K T+P C+VC++ +++ D +
Sbjct: 221 IRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQN-DVVRI 279
Query: 969 MPCKHKFHVKCIVPWLELHNSFPVCRFEL 1055
+PCKH FH C+ PWL H + P+C+ +
Sbjct: 280 LPCKHVFHKSCVDPWLSEHCTCPMCKLNI 308
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,812,767,464
Number of Sequences: 518415
Number of Extensions: 55812767464
Number of Successful Extensions: 380683862
Number of sequences better than 0.0: 0
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