BLASTX 7.6.2
Query= UN13917 /QuerySize=1389
(1388 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9D8V0|HM13_MOUSE Minor histocompatibility antigen H13 OS=Mus... 253 3e-066
sp|Q8TCT9|HM13_HUMAN Minor histocompatibility antigen H13 OS=Hom... 250 2e-065
sp|Q9UTA3|YL8H_SCHPO Probable intramembrane protease C25B8.17 OS... 139 4e-032
sp|P49049|IMP2_CAEEL Intramembrane protease 2 OS=Caenorhabditis ... 131 2e-029
sp|P34248|YKK0_YEAST Probable intramembrane protease YKL100C OS=... 90 4e-017
sp|Q8TCT7|PSL1_HUMAN Signal peptide peptidase-like 2B OS=Homo sa... 74 2e-012
sp|Q5F383|PSL1_CHICK Signal peptide peptidase-like 2B OS=Gallus ... 74 2e-012
sp|Q3TD49|PSL1_MOUSE Signal peptide peptidase-like 2B OS=Mus mus... 73 5e-012
sp|Q8TCT8|PSL2_HUMAN Signal peptide peptidase-like 2A OS=Homo sa... 72 9e-012
sp|Q5PQL3|PSL1_RAT Signal peptide peptidase-like 2B OS=Rattus no... 71 2e-011
sp|Q8IUH8|IMP5_HUMAN Signal peptide peptidase-like 2C OS=Homo sa... 69 9e-011
sp|A2A6C4|IMP5_MOUSE Signal peptide peptidase-like 2C OS=Mus mus... 68 1e-010
>sp|Q9D8V0|HM13_MOUSE Minor histocompatibility antigen H13 OS=Mus musculus
GN=Hm13 PE=1 SV=1
Length = 378
Score = 253 bits (645), Expect = 3e-066
Identities = 144/334 (43%), Positives = 207/334 (61%), Gaps = 23/334 (6%)
Frame = -2
Query: 1168 NVVLTACLTVYVGCFRSVK------DSPPTETMSKEHAMRFPLVGSAMLLSLFLLFKFLS 1007
+++L A L ++ G RSV+ S ET++ A RFP++ S LL L+L FK S
Sbjct: 38 SLLLMALLPIFFGALRSVRCARGKSSSDMPETITSRDAARFPIIASCTLLGLYLFFKIFS 97
Query: 1006 KDLVNAVLTAYFFVLGIVALSATLLPAISRFLPKPWNDNLIVWRFPYFKS------LEVE 845
++ +N +L+ YFFVLGI+ALS T+ P +++F P + + F + E
Sbjct: 98 QEYINLLLSMYFFVLGILALSHTISPFMNKFFPANFPNRQYQLLFTQGSGENKEEIINYE 157
Query: 844 F-TKSQVVAGIPGTFFCAWYAWKKHWLANNILGLSFCIQGIEMLSLGSFKTGAILLVGLF 668
F TK V G+ + WY +KHW+ANN+ GL+F + G+E+L L + TG ILL GLF
Sbjct: 158 FDTKDLVCLGL-SSVVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLF 216
Query: 667 FYDIFWVFFTPVMVSVAKSFDAPIKLLFP-----TGDALRPYSMLGLGDIVIPGIFVALA 503
YDIFWVF T VMV+VAKSF+APIKL+FP G ++MLGLGDIVIPGIF+AL
Sbjct: 217 IYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALL 276
Query: 502 LRFDVS-RRSKPQYFTSAFVGYVAGVVLTIVVMNWFQAAQPALLYIVPAVIGFLASHCIW 326
LRFD+S +++ YF ++F Y+ G+ LTI +M+ F+ AQPALLY+VPA IGF +
Sbjct: 277 LRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALA 336
Query: 325 NGDIKPLMAFDESS---KSSEEESKSSEGEVNKS 233
G++ + +++ES+ ++E ESK E + S
Sbjct: 337 KGEVAEMFSYEESNPKDPAAETESKEESTEASAS 370
>sp|Q8TCT9|HM13_HUMAN Minor histocompatibility antigen H13 OS=Homo sapiens
GN=HM13 PE=1 SV=1
Length = 377
Score = 250 bits (638), Expect = 2e-065
Identities = 140/327 (42%), Positives = 204/327 (62%), Gaps = 21/327 (6%)
Frame = -2
Query: 1168 NVVLTACLTVYVGCFRSVK------DSPPTETMSKEHAMRFPLVGSAMLLSLFLLFKFLS 1007
+++L A L ++ G RSV+ S ET++ A RFP++ S LL L+L FK S
Sbjct: 38 SLLLMALLPIFFGALRSVRCARGKNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFS 97
Query: 1006 KDLVNAVLTAYFFVLGIVALSATLLPAISRFLPKPWNDNLIVWRFPYFKS------LEVE 845
++ +N +L+ YFFVLGI+ALS T+ P +++F P + + F + E
Sbjct: 98 QEYINLLLSMYFFVLGILALSHTISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYE 157
Query: 844 F-TKSQVVAGIPGTFFCAWYAWKKHWLANNILGLSFCIQGIEMLSLGSFKTGAILLVGLF 668
F TK V G+ + WY +KHW+ANN+ GL+F + G+E+L L + TG ILL GLF
Sbjct: 158 FDTKDLVCLGL-SSIVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLF 216
Query: 667 FYDIFWVFFTPVMVSVAKSFDAPIKLLFP-----TGDALRPYSMLGLGDIVIPGIFVALA 503
YD+FWVF T VMV+VAKSF+APIKL+FP G ++MLGLGD+VIPGIF+AL
Sbjct: 217 IYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALL 276
Query: 502 LRFDVS-RRSKPQYFTSAFVGYVAGVVLTIVVMNWFQAAQPALLYIVPAVIGFLASHCIW 326
LRFD+S +++ YF ++F Y+ G+ LTI +M+ F+ AQPALLY+VPA IGF +
Sbjct: 277 LRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALA 336
Query: 325 NGDIKPLMAFDESS-KSSEEESKSSEG 248
G++ + +++ES+ K ++S EG
Sbjct: 337 KGEVTEMFSYEESNPKDPAAVTESKEG 363
>sp|Q9UTA3|YL8H_SCHPO Probable intramembrane protease C25B8.17
OS=Schizosaccharomyces pombe GN=SPAC25B8.17 PE=2 SV=1
Length = 295
Score = 139 bits (350), Expect = 4e-032
Identities = 92/265 (34%), Positives = 141/265 (53%), Gaps = 19/265 (7%)
Frame = -2
Query: 1006 KDLVNAVLTAYFFVLGIVALSATLLPAISRFLPKPWNDNLIVWRFP-------YFKSLEV 848
K L+N L F + G V L L+ R+L K + LI+ + + +S
Sbjct: 30 KQLINKRLAVLFPIFGGVTL--VLMYLALRYLSKEY-IQLILQGYASLASIICFVRSFNP 86
Query: 847 EFTKSQVVAGIPGTFFCAWYAWKKHWLANNILGLSFCIQGIEMLSLGSFKTGAILLVGLF 668
+ T ++ A + +Y KHW+A+NIL + I ++ + S+ TGA+LL LF
Sbjct: 87 KTTFGKITATMSSIAIALFYFKTKHWMASNILAWALAANSISIMRIDSYNTGALLLGALF 146
Query: 667 FYDIFWVFFTPVMVSVAKSFDAPIKLLFPTGDALRPYSMLGLGDIVIPGIFVALALRFD- 491
FYDI++VF T VMV+VA D P K + P SMLGLGDIV+PG+ +AL RFD
Sbjct: 147 FYDIYFVFGTEVMVTVATGIDIPAKYVLPQFKNPTRLSMLGLGDIVMPGLMLALMYRFDL 206
Query: 490 ---VSRRSKPQ----YFTSAFVGYVAGVVLTIVVMNWFQAAQPALLYIVPAVIGFLASHC 332
++ S+P+ YF + F+ Y G+ +T + +F+AAQPALLY+ PA I
Sbjct: 207 HYYINSTSQPKKHSTYFRNTFIAYGLGLGVTNFALYYFKAAQPALLYLSPACIVAPLLTA 266
Query: 331 IWNGDIKPLMAF-DESSKSSEEESK 260
+ ++K L +F E+ ++E+ K
Sbjct: 267 WYRDELKTLFSFRSETEDETDEQDK 291
>sp|P49049|IMP2_CAEEL Intramembrane protease 2 OS=Caenorhabditis elegans
GN=imp-2 PE=1 SV=1
Length = 468
Score = 131 bits (327), Expect = 2e-029
Identities = 70/128 (54%), Positives = 87/128 (67%), Gaps = 8/128 (6%)
Frame = -2
Query: 853 EVEFTKSQVVAGIPGTFFCAWYAWKKHWLANNILGLSFCIQGIEMLSLGSFKTGAILLVG 674
+++F + ++A + + + K+HW+ NNI+G+SF I GIE L L SFK G++LLVG
Sbjct: 242 KIDFDRYDIIALLMCSPILISHLLKRHWITNNIIGVSFSILGIERLHLASFKAGSLLLVG 301
Query: 673 LFFYDIFWVFFTPVMVSVAKSFDAPIKLLFPTGDALR-------PYSMLGLGDIVIPGIF 515
LFFYDIFWVF T VM SVAK DAPI L FP D R +SMLGLGDIVIPGIF
Sbjct: 302 LFFYDIFWVFGTDVMTSVAKGIDAPILLQFPQ-DIYRNGIMEASKHSMLGLGDIVIPGIF 360
Query: 514 VALALRFD 491
+AL RFD
Sbjct: 361 IALLRRFD 368
Score = 56 bits (133), Expect = 6e-007
Identities = 28/79 (35%), Positives = 44/79 (55%)
Frame = -2
Query: 466 YFTSAFVGYVAGVVLTIVVMNWFQAAQPALLYIVPAVIGFLASHCIWNGDIKPLMAFDES 287
YF V Y+AG+ +T+ VM+ F+AAQPALLY+VP + + G++ L +DES
Sbjct: 390 YFVVTVVAYMAGLFITMAVMHHFKAAQPALLYLVPCCLFVPLLLAVIRGELSALWNYDES 449
Query: 286 SKSSEEESKSSEGEVNKSH 230
EE++ K++
Sbjct: 450 RHVDNEENRKKVDSGKKNN 468
>sp|P34248|YKK0_YEAST Probable intramembrane protease YKL100C OS=Saccharomyces
cerevisiae GN=YKL100C PE=1 SV=1
Length = 587
Score = 90 bits (221), Expect = 4e-017
Identities = 44/106 (41%), Positives = 67/106 (63%), Gaps = 4/106 (3%)
Frame = -2
Query: 793 WYAWKKHWLANNILGLSFCIQGIEMLSLGSFKTGAILLVGLFFYDIFWVFFTPVMVSVAK 614
+Y WL +N + ++ I I L L + K+GA++L+ LFFYDI +VF T VMV+VA
Sbjct: 322 FYLSPNDWLISNAVSMNMAIWSIAQLKLKNLKSGALILIALFFYDICFVFGTDVMVTVAT 381
Query: 613 SFDAPIKLLFP----TGDALRPYSMLGLGDIVIPGIFVALALRFDV 488
+ D P+KL P T +S+LGLGDI +PG+F+A+ ++D+
Sbjct: 382 NLDIPVKLSLPVKFNTAQNNFNFSILGLGDIALPGMFIAMCYKYDI 427
>sp|Q8TCT7|PSL1_HUMAN Signal peptide peptidase-like 2B OS=Homo sapiens GN=SPPL2B
PE=1 SV=2
Length = 592
Score = 74 bits (181), Expect = 2e-012
Identities = 36/108 (33%), Positives = 61/108 (56%), Gaps = 6/108 (5%)
Frame = -2
Query: 637 PVMVSVAKSFDAPIKLLFPTGDALRPYSMLGLGDIVIPGIFVALALRFDVSRRSKPQYFT 458
P+++ V + +P+ L RP+S+LG GDI++PG+ VA RFD+ +S YF
Sbjct: 394 PMVLKVPRLNSSPLAL------CDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRVYFV 447
Query: 457 SAFVGYVAGVVLTIVVMNWFQAAQPALLYIVPAVIGFLASHCIWNGDI 314
+ + Y G+++T V + Q QPALLY+VP + + +W ++
Sbjct: 448 ACTIAYGVGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRREL 495
>sp|Q5F383|PSL1_CHICK Signal peptide peptidase-like 2B OS=Gallus gallus
GN=SPPL2B PE=2 SV=1
Length = 596
Score = 74 bits (180), Expect = 2e-012
Identities = 37/108 (34%), Positives = 61/108 (56%), Gaps = 6/108 (5%)
Frame = -2
Query: 637 PVMVSVAKSFDAPIKLLFPTGDALRPYSMLGLGDIVIPGIFVALALRFDVSRRSKPQYFT 458
P+++ V + +P+ L RP+S+LG GDI++PG+ VA RFD+ +S YF
Sbjct: 390 PMVLKVPRLNSSPLAL------CDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRVYFV 443
Query: 457 SAFVGYVAGVVLTIVVMNWFQAAQPALLYIVPAVIGFLASHCIWNGDI 314
+ + Y G+++T V + Q QPALLY+VP + S +W ++
Sbjct: 444 ACTIAYGIGLLVTFVALALMQMGQPALLYLVPCTLITSFSVALWRKEL 491
>sp|Q3TD49|PSL1_MOUSE Signal peptide peptidase-like 2B OS=Mus musculus GN=Sppl2b
PE=2 SV=2
Length = 578
Score = 73 bits (177), Expect = 5e-012
Identities = 36/108 (33%), Positives = 61/108 (56%), Gaps = 6/108 (5%)
Frame = -2
Query: 637 PVMVSVAKSFDAPIKLLFPTGDALRPYSMLGLGDIVIPGIFVALALRFDVSRRSKPQYFT 458
P+++ V + +P+ L RP+S+LG GDI++PG+ VA RFD+ +S YF
Sbjct: 387 PMVLKVPRLNTSPLSL------CDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFV 440
Query: 457 SAFVGYVAGVVLTIVVMNWFQAAQPALLYIVPAVIGFLASHCIWNGDI 314
+ + Y G+++T V + Q QPALLY+VP + + +W ++
Sbjct: 441 ACTIAYGLGLLVTFVALVLMQRGQPALLYLVPCTLLTSCTVALWRREL 488
>sp|Q8TCT8|PSL2_HUMAN Signal peptide peptidase-like 2A OS=Homo sapiens GN=SPPL2A
PE=1 SV=2
Length = 520
Score = 72 bits (175), Expect = 9e-012
Identities = 36/81 (44%), Positives = 49/81 (60%), Gaps = 1/81 (1%)
Frame = -2
Query: 568 LRPYSMLGLGDIVIPGIFVALALRFDVSRRSKPQYFTSAFVGYVAGVVLTIVVMNWFQAA 389
L P S+LG GDI++PG+ +A RFDV S Y+ S+ V Y G++LT VV+ +
Sbjct: 402 LMPVSILGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKG 461
Query: 388 QPALLYIVPAVIGFLASHCIW 326
QPALLY+VP + AS W
Sbjct: 462 QPALLYLVPCTL-ITASVVAW 481
>sp|Q5PQL3|PSL1_RAT Signal peptide peptidase-like 2B OS=Rattus norvegicus
GN=Sppl2b PE=2 SV=1
Length = 577
Score = 71 bits (172), Expect = 2e-011
Identities = 40/148 (27%), Positives = 74/148 (50%), Gaps = 6/148 (4%)
Frame = -2
Query: 637 PVMVSVAKSFDAPIKLLFPTGDALRPYSMLGLGDIVIPGIFVALALRFDVSRRSKPQYFT 458
P+++ V + +P+ L RP+S+LG GDI++PG+ VA RFD+ +S YF
Sbjct: 387 PMVLKVPRLNTSPLSL------CDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFV 440
Query: 457 SAFVGYVAGVVLTIVVMNWFQAAQPALLYIVPAVIGFLASHCIWNGDIKPLMAFDESSKS 278
+ + Y G+++T V + + QPALLY+VP + + +W ++ + +
Sbjct: 441 ACTIAYGLGLLVTFVALVLMRHGQPALLYLVPCTLLTSCTVALWRREMGAFWTGSGFADA 500
Query: 277 SEEESKSSEGEVNKSHAE*SKMWRKKGE 194
+ + +G V + S + +GE
Sbjct: 501 PQTPWAAPQGPVPPKDVDASLSEQPRGE 528
>sp|Q8IUH8|IMP5_HUMAN Signal peptide peptidase-like 2C OS=Homo sapiens GN=SPPL2C
PE=1 SV=3
Length = 684
Score = 69 bits (166), Expect = 9e-011
Identities = 32/71 (45%), Positives = 45/71 (63%)
Frame = -2
Query: 565 RPYSMLGLGDIVIPGIFVALALRFDVSRRSKPQYFTSAFVGYVAGVVLTIVVMNWFQAAQ 386
+P+S+LG GDIV+PG VA RFDV S+ YF + V Y G+++T + M Q Q
Sbjct: 439 QPFSILGFGDIVVPGFLVAYCCRFDVQVCSRQIYFVACTVAYAVGLLVTFMAMVLMQMGQ 498
Query: 385 PALLYIVPAVI 353
PALLY+V + +
Sbjct: 499 PALLYLVSSTL 509
>sp|A2A6C4|IMP5_MOUSE Signal peptide peptidase-like 2C OS=Mus musculus GN=Sppl2c
PE=2 SV=1
Length = 690
Score = 68 bits (165), Expect = 1e-010
Identities = 31/71 (43%), Positives = 46/71 (64%)
Frame = -2
Query: 565 RPYSMLGLGDIVIPGIFVALALRFDVSRRSKPQYFTSAFVGYVAGVVLTIVVMNWFQAAQ 386
+P+S+LG GDIV+PG VA RFD+ +S+ Y+ + V Y G+++T V M Q Q
Sbjct: 448 QPFSILGFGDIVVPGFLVAYCHRFDMQVQSRQVYYMACTVAYAVGLLVTFVAMILMQMGQ 507
Query: 385 PALLYIVPAVI 353
PALLY+V + +
Sbjct: 508 PALLYLVSSTL 518
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,812,767,464
Number of Sequences: 518415
Number of Extensions: 55812767464
Number of Successful Extensions: 380683862
Number of sequences better than 0.0: 0
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