BLASTX 7.6.2
Query= UN14022 /QuerySize=1000
(999 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O00232|PSD12_HUMAN 26S proteasome non-ATPase regulatory subun... 206 2e-052
sp|Q5RBI3|PSD12_PONAB 26S proteasome non-ATPase regulatory subun... 206 2e-052
sp|Q2KJ25|PSD12_BOVIN 26S proteasome non-ATPase regulatory subun... 204 9e-052
sp|Q9D8W5|PSD12_MOUSE 26S proteasome non-ATPase regulatory subun... 201 6e-051
sp|Q54UJ0|PSD12_DICDI 26S proteasome non-ATPase regulatory subun... 198 5e-050
sp|Q12250|RPN5_YEAST 26S proteasome regulatory subunit RPN5 OS=S... 166 2e-040
sp|Q9UTM3|RPN5_SCHPO 26S proteasome regulatory subunit rpn5 OS=S... 151 1e-035
sp|Q9N359|CSN4_CAEEL COP9 signalosome complex subunit 4 OS=Caeno... 66 4e-010
sp|Q3SZA0|CSN4_BOVIN COP9 signalosome complex subunit 4 OS=Bos t... 55 7e-007
sp|Q6P0H6|CSN4_DANRE COP9 signalosome complex subunit 4 OS=Danio... 55 7e-007
sp|Q9BT78|CSN4_HUMAN COP9 signalosome complex subunit 4 OS=Homo ... 55 7e-007
sp|Q4R5E6|CSN4_MACFA COP9 signalosome complex subunit 4 OS=Macac... 55 7e-007
sp|O88544|CSN4_MOUSE COP9 signalosome complex subunit 4 OS=Mus m... 55 7e-007
sp|A7Y521|CSN4_PIG COP9 signalosome complex subunit 4 OS=Sus scr... 55 7e-007
sp|Q5R648|CSN4_PONAB COP9 signalosome complex subunit 4 OS=Pongo... 55 7e-007
sp|Q68FS2|CSN4_RAT COP9 signalosome complex subunit 4 OS=Rattus ... 55 7e-007
sp|Q54B82|CSN4_DICDI COP9 signalosome complex subunit 4 OS=Dicty... 54 2e-006
>sp|O00232|PSD12_HUMAN 26S proteasome non-ATPase regulatory subunit 12 OS=Homo
sapiens GN=PSMD12 PE=1 SV=3
Length = 456
Score = 206 bits (524), Expect = 2e-052
Identities = 105/233 (45%), Positives = 151/233 (64%), Gaps = 7/233 (3%)
Frame = +3
Query: 93 ELKRIYYELMIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPHD 272
+LK YY LMI+ H YL IC+ Y+AIYD P ++ E+W L+ + +++LAP D
Sbjct: 221 KLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFD 280
Query: 273 PMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKY-----KGEFENEKSMV 437
QS L++ DK L EIP +K LLK TME+++W+ L Y KG E+ + V
Sbjct: 281 NEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDV 340
Query: 438 GGSL--GDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSK 611
GS G+K +DLK R++EHNI +++KYY+RIT+KR+A+LL LS++E+E LS +VV+K
Sbjct: 341 FGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNK 400
Query: 612 ALIAKIDRPSGIVCFQIAKDSNEILNSWAVNLEKLLDLVEKSCHQIHKETMVH 770
+ AK+DR +GI+ FQ KD N +LN W+ L L+ LV K+ H I KE M+H
Sbjct: 401 TIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIH 453
>sp|Q5RBI3|PSD12_PONAB 26S proteasome non-ATPase regulatory subunit 12 OS=Pongo
abelii GN=PSMD12 PE=2 SV=3
Length = 456
Score = 206 bits (524), Expect = 2e-052
Identities = 105/233 (45%), Positives = 151/233 (64%), Gaps = 7/233 (3%)
Frame = +3
Query: 93 ELKRIYYELMIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPHD 272
+LK YY LMI+ H YL IC+ Y+AIYD P ++ E+W L+ + +++LAP D
Sbjct: 221 KLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFD 280
Query: 273 PMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKY-----KGEFENEKSMV 437
QS L++ DK L EIP +K LLK TME+++W+ L Y KG E+ + V
Sbjct: 281 NEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDV 340
Query: 438 GGSL--GDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSK 611
GS G+K +DLK R++EHNI +++KYY+RIT+KR+A+LL LS++E+E LS +VV+K
Sbjct: 341 FGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNK 400
Query: 612 ALIAKIDRPSGIVCFQIAKDSNEILNSWAVNLEKLLDLVEKSCHQIHKETMVH 770
+ AK+DR +GI+ FQ KD N +LN W+ L L+ LV K+ H I KE M+H
Sbjct: 401 TIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIH 453
>sp|Q2KJ25|PSD12_BOVIN 26S proteasome non-ATPase regulatory subunit 12 OS=Bos
taurus GN=PSMD12 PE=2 SV=3
Length = 456
Score = 204 bits (518), Expect = 9e-052
Identities = 104/233 (44%), Positives = 150/233 (64%), Gaps = 7/233 (3%)
Frame = +3
Query: 93 ELKRIYYELMIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPHD 272
+LK YY LMI+ H YL IC+ Y+AIYD P ++ E+W L+ + +++LAP D
Sbjct: 221 KLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFD 280
Query: 273 PMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKY-----KGEFENEKSMV 437
QS L++ DK L EIP +K LLK TME+++W+ L Y KG E+ + V
Sbjct: 281 NEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDV 340
Query: 438 GG--SLGDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSK 611
G G+K +DLK R++EHNI +++KYY+RIT+KR+A+LL LS++E+E LS +VV+K
Sbjct: 341 FGYTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNK 400
Query: 612 ALIAKIDRPSGIVCFQIAKDSNEILNSWAVNLEKLLDLVEKSCHQIHKETMVH 770
+ AK+DR +GI+ FQ KD N +LN W+ L L+ LV K+ H I KE M+H
Sbjct: 401 TIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIH 453
>sp|Q9D8W5|PSD12_MOUSE 26S proteasome non-ATPase regulatory subunit 12 OS=Mus
musculus GN=Psmd12 PE=2 SV=3
Length = 456
Score = 201 bits (511), Expect = 6e-051
Identities = 101/232 (43%), Positives = 148/232 (63%), Gaps = 7/232 (3%)
Frame = +3
Query: 96 LKRIYYELMIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPHDP 275
+K YY LMI+ H YL IC+ Y+AIYD P ++ ++W L+ + +++LAP D
Sbjct: 222 MKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESDKWQQALKSVVLYVILAPFDN 281
Query: 276 MQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKY-----KGEFENEKSMVG 440
QS L++ DK L EIP +K LLK TME+++W+ L Y KG E + V
Sbjct: 282 EQSDLVHRISSDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGVELRKGSSETPATDVF 341
Query: 441 GSL--GDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKA 614
S G+K +DLK R++EHNI +++KYY+RIT+KR+A+LL LS++E+E LS +VV+K
Sbjct: 342 SSTEEGEKRWKDLKSRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKT 401
Query: 615 LIAKIDRPSGIVCFQIAKDSNEILNSWAVNLEKLLDLVEKSCHQIHKETMVH 770
+ AK+DR +G++ FQ KD N +LN W+ L L+ LV K+ H I KE M+H
Sbjct: 402 IFAKVDRLAGVINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIH 453
>sp|Q54UJ0|PSD12_DICDI 26S proteasome non-ATPase regulatory subunit 12
OS=Dictyostelium discoideum GN=psmD12 PE=2 SV=1
Length = 447
Score = 198 bits (503), Expect = 5e-050
Identities = 101/227 (44%), Positives = 150/227 (66%), Gaps = 3/227 (1%)
Frame = +3
Query: 93 ELKRIYYELMIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPHD 272
+LK Y++ MIRY+SH+ Y+EI R Y +IYD PSV++ Q + L+ IC +++L+
Sbjct: 222 DLKIDYFKQMIRYFSHSANYIEIARCYLSIYDTPSVEKDTPQLLQTLKYICIYVILSASS 281
Query: 273 PMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKYKGEFENEKSMVGGSLG 452
QS LLN E K L++I ++K LL Q T+E+I+W+ + K E +++
Sbjct: 282 NEQSDLLNRVYEFKPLTDIQNYKDLLNQFKTLELIRWSTFFELNKPELDSQTVF---KTE 338
Query: 453 DKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALIAKID 632
A EDL+ R+IEHNI V+S YY +I+ RLAELL LS++E+EK +S++V +K + AKID
Sbjct: 339 PNAWEDLRKRVIEHNIRVISTYYQKISTARLAELLDLSLDESEKFVSDLVSNKTIFAKID 398
Query: 633 RPSGIVCFQIAKDSNEILNSWAVNLEKLLDLVEKSCHQIHKETMVHK 773
RP+GI F D N++LN+WA N+ LLDLVEK+ H + +E M+HK
Sbjct: 399 RPAGIATFTTTNDPNKVLNAWANNITSLLDLVEKTNHLVQREFMLHK 445
>sp|Q12250|RPN5_YEAST 26S proteasome regulatory subunit RPN5 OS=Saccharomyces
cerevisiae GN=RPN5 PE=1 SV=3
Length = 445
Score = 166 bits (420), Expect = 2e-040
Identities = 84/230 (36%), Positives = 138/230 (60%)
Frame = +3
Query: 81 PTLLELKRIYYELMIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVL 260
P LK YY L+++ H EYLE+ + + IY ++K +W PVL I +FLVL
Sbjct: 211 PKYESLKLEYYNLLVKISLHKREYLEVAQYLQEIYQTDAIKSDEAKWKPVLSHIVYFLVL 270
Query: 261 APHDPMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKYKGEFENEKSMVG 440
+P+ +Q+ L++ D NL ++ + L+K T E+++W + Y+ + G
Sbjct: 271 SPYGNLQNDLIHKIQNDNNLKKLESQESLVKLFTTNELMRWPIVQKTYEPVLNEDDLAFG 330
Query: 441 GSLGDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALI 620
G EDL+ R+IEHN+ V+S+YYSRITL RL ELL L+ + E ++S++V +
Sbjct: 331 GEANKHHWEDLQKRVIEHNLRVISEYYSRITLLRLNELLDLTESQTETYISDLVNQGIIY 390
Query: 621 AKIDRPSGIVCFQIAKDSNEILNSWAVNLEKLLDLVEKSCHQIHKETMVH 770
AK++RP+ IV F+ K+S+++LN W+ N+++LL+ +E H I KE ++H
Sbjct: 391 AKVNRPAKIVNFEKPKNSSQLLNEWSHNVDELLEHIETIGHLITKEEIMH 440
>sp|Q9UTM3|RPN5_SCHPO 26S proteasome regulatory subunit rpn5
OS=Schizosaccharomyces pombe GN=rpn5a PE=1 SV=1
Length = 443
Score = 151 bits (379), Expect = 1e-035
Identities = 81/226 (35%), Positives = 127/226 (56%), Gaps = 1/226 (0%)
Frame = +3
Query: 96 LKRIYYELMIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPHDP 275
LK YYE IR H++ YL++C+ Y+A+YD V+E PE+W +L + F +L P+D
Sbjct: 210 LKLKYYEQKIRIGLHDDAYLDVCKYYRAVYDTAVVQEDPEKWKEILENVVCFALLTPYDN 269
Query: 276 MQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKYKGEF-ENEKSMVGGSLG 452
Q+ LL+ D L+ +P + L+K + E+++W + Y N G
Sbjct: 270 EQADLLHRINADHKLNSLPLLQQLVKCFIVNELMRWPKIAEIYGSALRSNPVFAENDEKG 329
Query: 453 DKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALIAKID 632
+K +L+ R+IEHNI VV+ YYSRI RL LL +S E E+ L +++ AKID
Sbjct: 330 EKRWSELRKRVIEHNIRVVANYYSRIHCSRLGVLLDMSPSETEQFLCDLIAKHHFYAKID 389
Query: 633 RPSGIVCFQIAKDSNEILNSWAVNLEKLLDLVEKSCHQIHKETMVH 770
RP+ ++ F+ +++ E LN W N+ +LL +EK I KE M++
Sbjct: 390 RPAQVISFKKSQNVQEQLNEWGSNITELLGKLEKVRQLIIKEEMMN 435
>sp|Q9N359|CSN4_CAEEL COP9 signalosome complex subunit 4 OS=Caenorhabditis
elegans GN=csn-4 PE=1 SV=1
Length = 412
Score = 66 bits (159), Expect = 4e-010
Identities = 57/209 (27%), Positives = 95/209 (45%), Gaps = 19/209 (9%)
Frame = +3
Query: 117 LMIRYYSHNNEYLEICRSYKAIYDIPSVKETP-EQWIPVLRKICWFLVLAPHDPMQSSLL 293
L R ++E + Y Y++ + ++ P + L K ++LA P +S LL
Sbjct: 203 LQARVSDAKRRFVEAAQRY---YELSATEQLPNSDKLTALGKAIVCVLLAKPGPQRSRLL 259
Query: 294 NATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKYKGEFEN-EKSMVGGSLGDKAGED 470
+D+ + F+++ K +T + +K E E E + D+ GE
Sbjct: 260 TLIFKDERAPKCASFELIAKMYLTKVI---------HKDELEEFEHQLQDHQKADEHGES 310
Query: 471 -LKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALIAKIDRPSGI 647
LK I EHNI +S+ Y I+ K L +LL + E AE EM+ S+ L ID+ +GI
Sbjct: 311 ILKGVIQEHNITAISQLYINISFKTLGQLLGVDTEAAESMAGEMISSERLHGYIDQTNGI 370
Query: 648 VCFQIAKDSNEILNSWAVNLEKLLDLVEK 734
+ F+ DSN + W + L+ + K
Sbjct: 371 LHFE---DSNP-MRVWDSQILSTLEQINK 395
>sp|Q3SZA0|CSN4_BOVIN COP9 signalosome complex subunit 4 OS=Bos taurus GN=COPS4
PE=2 SV=1
Length = 406
Score = 55 bits (131), Expect = 7e-007
Identities = 51/211 (24%), Positives = 97/211 (45%), Gaps = 17/211 (8%)
Frame = +3
Query: 93 ELKRIYYEL-MIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPH 269
E +I+Y++ R + +++E + Y + V E+ + + L+ +LA
Sbjct: 181 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHES--ERLEALKHALHCTILASA 238
Query: 270 DPMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKYKGEFENEKSMV--GG 443
+S +L +D+ ++ + +L K + +I+ L ++K+ G
Sbjct: 239 GQQRSRMLATLFKDERCQQLAAYGILEKMYLD-RIIRGNQLQEFAAMLMPHQKATTADGS 297
Query: 444 SLGDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALIA 623
S+ D+A +IEHN+L SK Y+ IT + L LL + +AEK S+M+ +
Sbjct: 298 SILDRA-------VIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNG 350
Query: 624 KIDRPSGIVCFQIAKDSNEILNSWAVNLEKL 716
ID+ GIV F ++ E L +W ++ L
Sbjct: 351 FIDQIDGIVHF----ETREALPTWDKQIQSL 377
>sp|Q6P0H6|CSN4_DANRE COP9 signalosome complex subunit 4 OS=Danio rerio GN=cops4
PE=2 SV=1
Length = 406
Score = 55 bits (131), Expect = 7e-007
Identities = 52/211 (24%), Positives = 97/211 (45%), Gaps = 17/211 (8%)
Frame = +3
Query: 93 ELKRIYYEL-MIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPH 269
E +I+Y++ R + +++E + Y + V ET + + L+ +LA
Sbjct: 181 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKSIVHET--ERLEALKHALHCTILASA 238
Query: 270 DPMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKYKGEFENEKSMV--GG 443
+S +L +D+ ++ + +L K + +I+ L ++K+ G
Sbjct: 239 GQQRSRMLATLFKDERCQQLAAYGILEKMYLD-RIIRGNQLQEFAAMLMPHQKATTADGS 297
Query: 444 SLGDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALIA 623
S+ D+A +IEHN+L SK Y+ IT + L LL + +AEK S+M+ +
Sbjct: 298 SILDRA-------VIEHNLLSASKLYNNITFEELGALLEIPPAKAEKIASQMITEGRMNG 350
Query: 624 KIDRPSGIVCFQIAKDSNEILNSWAVNLEKL 716
ID+ GIV F ++ E L +W ++ L
Sbjct: 351 FIDQIDGIVHF----ETREPLPTWDKQIQSL 377
>sp|Q9BT78|CSN4_HUMAN COP9 signalosome complex subunit 4 OS=Homo sapiens
GN=COPS4 PE=1 SV=1
Length = 406
Score = 55 bits (131), Expect = 7e-007
Identities = 51/211 (24%), Positives = 97/211 (45%), Gaps = 17/211 (8%)
Frame = +3
Query: 93 ELKRIYYEL-MIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPH 269
E +I+Y++ R + +++E + Y + V E+ + + L+ +LA
Sbjct: 181 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHES--ERLEALKHALHCTILASA 238
Query: 270 DPMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKYKGEFENEKSMV--GG 443
+S +L +D+ ++ + +L K + +I+ L ++K+ G
Sbjct: 239 GQQRSRMLATLFKDERCQQLAAYGILEKMYLD-RIIRGNQLQEFAAMLMPHQKATTADGS 297
Query: 444 SLGDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALIA 623
S+ D+A +IEHN+L SK Y+ IT + L LL + +AEK S+M+ +
Sbjct: 298 SILDRA-------VIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNG 350
Query: 624 KIDRPSGIVCFQIAKDSNEILNSWAVNLEKL 716
ID+ GIV F ++ E L +W ++ L
Sbjct: 351 FIDQIDGIVHF----ETREALPTWDKQIQSL 377
>sp|Q4R5E6|CSN4_MACFA COP9 signalosome complex subunit 4 OS=Macaca fascicularis
GN=COPS4 PE=2 SV=1
Length = 406
Score = 55 bits (131), Expect = 7e-007
Identities = 51/211 (24%), Positives = 97/211 (45%), Gaps = 17/211 (8%)
Frame = +3
Query: 93 ELKRIYYEL-MIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPH 269
E +I+Y++ R + +++E + Y + V E+ + + L+ +LA
Sbjct: 181 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHES--ERLEALKHALHCTILASA 238
Query: 270 DPMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKYKGEFENEKSMV--GG 443
+S +L +D+ ++ + +L K + +I+ L ++K+ G
Sbjct: 239 GQQRSRMLATLFKDERCQQLAAYGILEKMYLD-RIIRGNQLQEFAAMLMPHQKATTADGS 297
Query: 444 SLGDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALIA 623
S+ D+A +IEHN+L SK Y+ IT + L LL + +AEK S+M+ +
Sbjct: 298 SILDRA-------VIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNG 350
Query: 624 KIDRPSGIVCFQIAKDSNEILNSWAVNLEKL 716
ID+ GIV F ++ E L +W ++ L
Sbjct: 351 FIDQIDGIVHF----ETREALPTWDKQIQSL 377
>sp|O88544|CSN4_MOUSE COP9 signalosome complex subunit 4 OS=Mus musculus
GN=Cops4 PE=1 SV=1
Length = 406
Score = 55 bits (131), Expect = 7e-007
Identities = 51/211 (24%), Positives = 97/211 (45%), Gaps = 17/211 (8%)
Frame = +3
Query: 93 ELKRIYYEL-MIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPH 269
E +I+Y++ R + +++E + Y + V E+ + + L+ +LA
Sbjct: 181 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHES--ERLEALKHALHCTILASA 238
Query: 270 DPMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKYKGEFENEKSMV--GG 443
+S +L +D+ ++ + +L K + +I+ L ++K+ G
Sbjct: 239 GQQRSRMLATLFKDERCQQLAAYGILEKMYLD-RIIRGNQLQEFAAMLMPHQKATTADGS 297
Query: 444 SLGDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALIA 623
S+ D+A +IEHN+L SK Y+ IT + L LL + +AEK S+M+ +
Sbjct: 298 SILDRA-------VIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNG 350
Query: 624 KIDRPSGIVCFQIAKDSNEILNSWAVNLEKL 716
ID+ GIV F ++ E L +W ++ L
Sbjct: 351 FIDQIDGIVHF----ETREALPTWDKQIQSL 377
>sp|A7Y521|CSN4_PIG COP9 signalosome complex subunit 4 OS=Sus scrofa GN=COPS4
PE=2 SV=1
Length = 406
Score = 55 bits (131), Expect = 7e-007
Identities = 51/211 (24%), Positives = 97/211 (45%), Gaps = 17/211 (8%)
Frame = +3
Query: 93 ELKRIYYEL-MIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPH 269
E +I+Y++ R + +++E + Y + V E+ + + L+ +LA
Sbjct: 181 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHES--ERLEALKHALHCTILASA 238
Query: 270 DPMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKYKGEFENEKSMV--GG 443
+S +L +D+ ++ + +L K + +I+ L ++K+ G
Sbjct: 239 GQQRSRMLATLFKDERCQQLAAYGILEKMYLD-RIIRGNQLQEFAAMLMPHQKATTADGS 297
Query: 444 SLGDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALIA 623
S+ D+A +IEHN+L SK Y+ IT + L LL + +AEK S+M+ +
Sbjct: 298 SILDRA-------VIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNG 350
Query: 624 KIDRPSGIVCFQIAKDSNEILNSWAVNLEKL 716
ID+ GIV F ++ E L +W ++ L
Sbjct: 351 FIDQIDGIVHF----ETREALPTWDKQIQSL 377
>sp|Q5R648|CSN4_PONAB COP9 signalosome complex subunit 4 OS=Pongo abelii
GN=COPS4 PE=2 SV=1
Length = 406
Score = 55 bits (131), Expect = 7e-007
Identities = 51/211 (24%), Positives = 97/211 (45%), Gaps = 17/211 (8%)
Frame = +3
Query: 93 ELKRIYYEL-MIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPH 269
E +I+Y++ R + +++E + Y + V E+ + + L+ +LA
Sbjct: 181 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHES--ERLEALKHALHCTILASA 238
Query: 270 DPMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKYKGEFENEKSMV--GG 443
+S +L +D+ ++ + +L K + +I+ L ++K+ G
Sbjct: 239 GQQRSRMLATLFKDERCQQLAAYGILEKMYLD-RIIRGNQLQEFAAMLMPHQKATTADGS 297
Query: 444 SLGDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALIA 623
S+ D+A +IEHN+L SK Y+ IT + L LL + +AEK S+M+ +
Sbjct: 298 SILDRA-------VIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNG 350
Query: 624 KIDRPSGIVCFQIAKDSNEILNSWAVNLEKL 716
ID+ GIV F ++ E L +W ++ L
Sbjct: 351 FIDQIDGIVHF----ETREALPTWDKQIQSL 377
>sp|Q68FS2|CSN4_RAT COP9 signalosome complex subunit 4 OS=Rattus norvegicus
GN=Cops4 PE=2 SV=1
Length = 406
Score = 55 bits (131), Expect = 7e-007
Identities = 51/211 (24%), Positives = 97/211 (45%), Gaps = 17/211 (8%)
Frame = +3
Query: 93 ELKRIYYEL-MIRYYSHNNEYLEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPH 269
E +I+Y++ R + +++E + Y + V E+ + + L+ +LA
Sbjct: 181 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHES--ERLEALKHALHCTILASA 238
Query: 270 DPMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTALWNKYKGEFENEKSMV--GG 443
+S +L +D+ ++ + +L K + +I+ L ++K+ G
Sbjct: 239 GQQRSRMLATLFKDERCQQLAAYGILEKMYLD-RIIRGNQLQEFAAMLMPHQKATTADGS 297
Query: 444 SLGDKAGEDLKLRIIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALIA 623
S+ D+A +IEHN+L SK Y+ IT + L LL + +AEK S+M+ +
Sbjct: 298 SILDRA-------VIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNG 350
Query: 624 KIDRPSGIVCFQIAKDSNEILNSWAVNLEKL 716
ID+ GIV F ++ E L +W ++ L
Sbjct: 351 FIDQIDGIVHF----ETREALPTWDKQIQSL 377
>sp|Q54B82|CSN4_DICDI COP9 signalosome complex subunit 4 OS=Dictyostelium
discoideum GN=csn4 PE=2 SV=1
Length = 393
Score = 54 bits (127), Expect = 2e-006
Identities = 31/78 (39%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Frame = +3
Query: 483 IIEHNILVVSKYYSRITLKRLAELLCLSIEEAEKHLSEMVVSKALIAKIDRPSGIVCFQI 662
+IEHN+L SK Y+ IT L LL + E+AEK S+MV + LI ID+ ++ F+
Sbjct: 300 VIEHNLLSASKLYNNITFDELGSLLEIQAEKAEKVASKMVCEERLIGSIDQIERLIQFEN 359
Query: 663 AKDSNEILNSWAVNLEKL 716
DS L W +E L
Sbjct: 360 VGDS---LTQWDKKIEGL 374
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,771,599,260
Number of Sequences: 518415
Number of Extensions: 58771599260
Number of Successful Extensions: 389091298
Number of sequences better than 0.0: 0
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