BLASTX 7.6.2
Query= UN14075 /QuerySize=1349
(1348 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7Z5U6|WDR53_HUMAN WD repeat-containing protein 53 OS=Homo sa... 131 2e-029
sp|Q32KQ2|WDR53_BOVIN WD repeat-containing protein 53 OS=Bos tau... 126 5e-028
sp|Q9DB94|WDR53_MOUSE WD repeat-containing protein 53 OS=Mus mus... 121 2e-026
sp|Q54BI5|WDR53_DICDI WD repeat-containing protein 53 homolog OS... 89 5e-017
>sp|Q7Z5U6|WDR53_HUMAN WD repeat-containing protein 53 OS=Homo sapiens GN=WDR53
PE=2 SV=1
Length = 358
Score = 131 bits (327), Expect = 2e-029
Identities = 113/372 (30%), Positives = 170/372 (45%), Gaps = 46/372 (12%)
Frame = +3
Query: 123 GHKATATCCIASLDRPGLVVTSGEDGCICWFDLRCKDVQFTIDVGTEPVPSLCFKTGNED 302
GH + C AS + GL+ + E G + + + T G + V S+ F
Sbjct: 8 GHSSPVLCLNAS--KEGLLASGAEGGDLTAWGEDGTPLGHTRFQGADDVTSVLFSPSCPT 65
Query: 303 VLYASHGNEIKSFDVHTLSAGSWKPLESYSYNKDEVNQVVCNGRSSFLASADDSGDVKII 482
LYASHG I DV +L L+ + N++E+N + N + LASADDSG +KI+
Sbjct: 66 KLYASHGETISVLDVRSLK----DSLDHFHVNEEEINCLSLNQTENLLASADDSGAIKIL 121
Query: 483 DLGQKCLYKTLRAGHTSICSSVQFIPWRPWEVITGGLDSKLVLWDFSKGRSQKIIDFSSD 662
DL K + ++L+ H++ICSSV F P RP +++ GLD +++LW K R I + D
Sbjct: 122 DLENKKVIRSLKR-HSNICSSVAFRPQRPQSLVSCGLDMQVMLWSLQKARPLWITNLQED 180
Query: 663 T------HSSSGQCLNPAFVHSIAVPEMDMVDKLGKICAVARGDGIVDLINV-----ESE 809
S GQ LNPA HSI+V G I + DG V + V E E
Sbjct: 181 ETEEMEGPQSPGQLLNPALAHSISVA------SCGNIFSCGAEDGKVRIFRVMGVKCEQE 234
Query: 810 LSRKGASKGSSSSSSNNNVVKRVCL---DYSV--GGHKAAVSC-VAFSQFQGKGGFLISG 971
L KG + G V +VC Y + GG+ ++ A S+ + K
Sbjct: 235 LGFKGHTSG----------VSQVCFLPESYLLLTGGNDGKITLWDANSEVEKKQKSPTKR 284
Query: 972 GNDKTVKIWDCVR-----CLDSDKNNDNRDLLLHLNIDLNKKVNWLC-TNQSDSENLVVC 1133
+ K K C + ++ ++L LNI+ +KVNWL T +N++V
Sbjct: 285 THRKKPKRGTCTKQGGNTNASVTDEEEHGNILPKLNIEHGEKVNWLLGTKIKGHQNILVA 344
Query: 1134 DTTRVVKVYSIS 1169
D T + VY ++
Sbjct: 345 DQTSCISVYPLN 356
>sp|Q32KQ2|WDR53_BOVIN WD repeat-containing protein 53 OS=Bos taurus GN=WDR53
PE=2 SV=1
Length = 358
Score = 126 bits (315), Expect = 5e-028
Identities = 111/371 (29%), Positives = 169/371 (45%), Gaps = 46/371 (12%)
Frame = +3
Query: 123 GHKATATCCIASLDRPGLVVTSGEDGCICWFDLRCKDVQFTIDVGTEPVPSLCFKTGNED 302
GH + C AS + GLV + E G + + + T G E V ++ F
Sbjct: 8 GHSSPILCLNAS--QEGLVASGAEGGDLVVWGEDGTLLGHTCFQGAEDVTNVLFSPSCPT 65
Query: 303 VLYASHGNEIKSFDVHTLSAGSWKPLESYSYNKDEVNQVVCNGRSSFLASADDSGDVKII 482
LYASHG I DV +L +PL+ + N++E+N + N + LASADDSG +KI+
Sbjct: 66 KLYASHGETISILDVRSLK----EPLDDFHVNEEEINCLSLNETENLLASADDSGTIKIL 121
Query: 483 DLGQKCLYKTLRAGHTSICSSVQFIPWRPWEVITGGLDSKLVLWDFSKGRSQKIIDFSSD 662
DL K + ++L+ H++ICSSV F P RP +++ GLD +++LW+ K R I + D
Sbjct: 122 DLENKKISRSLKR-HSNICSSVAFRPQRPQSLVSCGLDMQVMLWNLRKARPLWITNLQED 180
Query: 663 ------THSSSGQCLNPAFVHSIAVPEMDMVDKLGKICAVARGDGIVDLINV-----ESE 809
+ S GQ LNPA HS++V G + + DG V + V E E
Sbjct: 181 ETEEMESPQSPGQLLNPALAHSVSVA------SCGNVFSCGAEDGKVRIFRVMGVKCEQE 234
Query: 810 LSRKGASKGSSSSSSNNNVVKRVCL---DYSV--GGHKAAVSC-VAFSQFQGKGGFLISG 971
L KG S G V +VC Y + GG+ + S+ + K
Sbjct: 235 LGFKGHSLG----------VSQVCFLRESYLLLTGGNDGKIKLWDVSSEIEKKHKSPTKH 284
Query: 972 GNDKTVKIWDCVR-----CLDSDKNNDNRDLLLHLNIDLNKKVNW-LCTNQSDSENLVVC 1133
+ K K + +++ +L L+I+ +KVNW L T N++V
Sbjct: 285 THRKKTKRAAYTKQGGGTHASVTGEDEHGKILPKLSIEHGEKVNWLLSTKIKGYRNILVA 344
Query: 1134 DTTRVVKVYSI 1166
D T + VY +
Sbjct: 345 DQTSCISVYPL 355
>sp|Q9DB94|WDR53_MOUSE WD repeat-containing protein 53 OS=Mus musculus GN=Wdr53
PE=2 SV=1
Length = 358
Score = 121 bits (302), Expect = 2e-026
Identities = 114/376 (30%), Positives = 173/376 (46%), Gaps = 54/376 (14%)
Frame = +3
Query: 123 GHKATATCCIASLDRPGLVVTSGEDG-CICWFDLRCKDVQFTIDVGTEPVPSLCFKTGNE 299
GH ++ C A+ D GLV + GE G + W + ++ G + V S+ F
Sbjct: 8 GHSSSILCLNANKD--GLVASGGEGGDLVAWGEDGTPLGHMQLE-GADDVTSVLFSASCP 64
Query: 300 DVLYASHGNEIKSFDVHTLSAGSWKPLESYSYNKDEVNQVVCNGRSSFLASADDSGDVKI 479
LYASHG I DV +L L+ + N++E+N + N S LASADDSG +KI
Sbjct: 65 TKLYASHGETISVLDVRSLKGS----LDHFHVNEEEINCLSLNETESLLASADDSGAIKI 120
Query: 480 IDLGQKCLYKTLRAGHTSICSSVQFIPWRPWEVITGGLDSKLVLWDFSKGRSQKIIDFSS 659
+DL +K + ++L+ H++ICSSV F P RP +++ GLD +++LW K R I +
Sbjct: 121 LDLEKKKVTRSLKR-HSNICSSVAFRPQRPQSLVSCGLDMQVMLWSLQKARPVWITNLQE 179
Query: 660 DTHSSS------GQCLNPAFVHSIAVPEMDMVDKLGKICAVARGDGIVDLINV-----ES 806
D + G+ LNPA HS++V G I + DG V + V E
Sbjct: 180 DETEETEGPQTPGRLLNPALAHSVSVA------SCGNIFSCGAEDGKVRIFRVMGVKCER 233
Query: 807 ELSRKGASKGSSSSSSNNNVVKRVC-LDYS----VGGHKAAVSCVAFSQFQGKGGFLISG 971
EL KG + G V +VC L S GG+ + S GK L
Sbjct: 234 ELGFKGHTLG----------VSQVCFLPESSLLLTGGNDGRIRLWDVS---GKMEKLQKS 280
Query: 972 G----NDKTVKIWDCVRCLDSDK-----NNDNRDLLLHLNIDLNKKVNW-LCTNQSDSEN 1121
+ K K C + + + + +L L+I+ +KVNW L T +++
Sbjct: 281 PARHIHRKKAKRAACPTQGGNSRAPGAEDEGHAKILPKLDIEHGEKVNWLLSTKIKGNKS 340
Query: 1122 LVVCDTTRVVKVYSIS 1169
++V D T V VY ++
Sbjct: 341 ILVADQTSCVSVYPLN 356
>sp|Q54BI5|WDR53_DICDI WD repeat-containing protein 53 homolog OS=Dictyostelium
discoideum GN=wdr53 PE=3 SV=1
Length = 368
Score = 89 bits (220), Expect = 5e-017
Identities = 56/175 (32%), Positives = 94/175 (53%), Gaps = 5/175 (2%)
Frame = +3
Query: 114 KLRGHKATATCCIASLDRPGLVVTSGEDGCICWFDLRC-KDVQFTID-VGTEPVPSLCFK 287
KL GHK T CI+S ++ ++ + +D + +DL K +Q ++ PV ++CF
Sbjct: 24 KLIGHKDT-VLCISSHNKKEIIASGSDDCTVRIWDLNTNKSIQSIVEGFQGNPVNNVCF- 81
Query: 288 TGNEDVLYASHGNEIKSFDVHTLSAGSWKPLESYSYNKDEVNQVVCNGRSSFLASADDSG 467
+ LY S+ N I SFD+ + + Y +N +E+NQ+ + + +LA+ DDSG
Sbjct: 82 -DQDFTLYCSYDNIIVSFDLRQPNVILKEFNTQYKFNTEEINQLSFDSKYQYLAACDDSG 140
Query: 468 DVKIIDLGQKCLYKTLRAGHTSICSSVQFIPWRPWEVITGGLDSKLVLWDFSKGR 632
KIID+ + L ++L HT+I + F P E+IT +D ++ WDF K +
Sbjct: 141 QTKIIDVTKNKLVESLNKKHTNIATGCVFRPNSKNELITSSMDFSIIHWDFLKAK 195
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,771,599,260
Number of Sequences: 518415
Number of Extensions: 58771599260
Number of Successful Extensions: 389091298
Number of sequences better than 0.0: 0
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