BLASTX 7.6.2
Query= UN14333 /QuerySize=1116
(1115 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P52894|ALA2_HORVU Alanine aminotransferase 2 OS=Hordeum vulga... 463 2e-129
sp|P34106|ALA2_PANMI Alanine aminotransferase 2 OS=Panicum milia... 461 4e-129
sp|Q54MJ7|ALAM_DICDI Probable alanine aminotransferase, mitochon... 335 4e-091
sp|Q6GM82|ALAT2_XENLA Alanine aminotransferase 2 OS=Xenopus laev... 294 1e-078
sp|Q28DB5|ALAT2_XENTR Alanine aminotransferase 2 OS=Xenopus trop... 288 6e-077
sp|Q8BGT5|ALAT2_MOUSE Alanine aminotransferase 2 OS=Mus musculus... 287 1e-076
sp|Q6NYL5|ALAT2_DANRE Alanine aminotransferase 2-like OS=Danio r... 286 3e-076
sp|Q8TD30|ALAT2_HUMAN Alanine aminotransferase 2 OS=Homo sapiens... 280 1e-074
sp|A4IFH5|ALAT1_BOVIN Alanine aminotransferase 1 OS=Bos taurus G... 273 2e-072
sp|P24298|ALAT1_HUMAN Alanine aminotransferase 1 OS=Homo sapiens... 270 1e-071
sp|Q8QZR5|ALAT1_MOUSE Alanine aminotransferase 1 OS=Mus musculus... 270 2e-071
sp|P25409|ALAT1_RAT Alanine aminotransferase 1 OS=Rattus norvegi... 269 3e-071
sp|P52893|ALAM_YEAST Probable alanine aminotransferase, mitochon... 247 1e-064
sp|Q10334|ALAT_SCHPO Putative alanine aminotransferase OS=Schizo... 245 4e-064
sp|P52892|ALAT_YEAST Probable alanine aminotransferase OS=Saccha... 240 2e-062
>sp|P52894|ALA2_HORVU Alanine aminotransferase 2 OS=Hordeum vulgare PE=2 SV=1
Length = 482
Score = 463 bits (1189), Expect = 2e-129
Identities = 221/286 (77%), Positives = 255/286 (89%)
Frame = +2
Query: 2 SGWGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLL 181
+GWGLE S++KKQLE+ARS+GI VRAL VINPGNPTGQVLAEENQ +IV FCK EGLVLL
Sbjct: 197 TGWGLETSDVKKQLEDARSRGINVRALVVINPGNPTGQVLAEENQYDIVKFCKNEGLVLL 256
Query: 182 ADEVYQENVYVPDKKFHSFKKVARSMGYGEKDICLVSFQSISKGYYGECGKRGGYMEVTG 361
ADEVYQEN+YV +KKFHSFKK+ RS+GYGE+D+ LVS+QS+SKGYYGECGKRGGY E+TG
Sbjct: 257 ADEVYQENIYVDNKKFHSFKKIVRSLGYGEEDLPLVSYQSVSKGYYGECGKRGGYFEITG 316
Query: 362 FTSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAK 541
F++ VREQIYK+ASVNLCSNI+GQILASLVM+PPK D+SY SY AEK+GIL+SLA+RAK
Sbjct: 317 FSAPVREQIYKIASVNLCSNITGQILASLVMNPPKASDESYASYKAEKDGILASLARRAK 376
Query: 542 TLEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVV 721
LE A NKLEG+TCN AEGAMY+FP I LPQKAI AA+AA APDAFY RLL +TGIVV
Sbjct: 377 ALEHAFNKLEGITCNEAEGAMYVFPQICLPQKAIEAAKAANKAPDAFYALRLLESTGIVV 436
Query: 722 VPGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEFRD 859
VPGSGF QVPGTWHFRCTILPQEDKIPA+++R T FH++FM E+RD
Sbjct: 437 VPGSGFGQVPGTWHFRCTILPQEDKIPAVISRFTVFHEAFMSEYRD 482
>sp|P34106|ALA2_PANMI Alanine aminotransferase 2 OS=Panicum miliaceum PE=1 SV=1
Length = 482
Score = 461 bits (1186), Expect = 4e-129
Identities = 222/286 (77%), Positives = 256/286 (89%)
Frame = +2
Query: 2 SGWGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLL 181
+GWGLEIS+LKKQLE+ARSKGI VRAL VINPGNPTGQVLAE+NQ +IV FCK EGLVLL
Sbjct: 197 TGWGLEISDLKKQLEDARSKGIDVRALVVINPGNPTGQVLAEDNQCDIVRFCKNEGLVLL 256
Query: 182 ADEVYQENVYVPDKKFHSFKKVARSMGYGEKDICLVSFQSISKGYYGECGKRGGYMEVTG 361
ADEVYQEN+YV DKKF+SFKK+ARS+GYGE D+ LVSFQS+SKGYYGECGKRGGYME+TG
Sbjct: 257 ADEVYQENIYVDDKKFNSFKKIARSVGYGEDDLPLVSFQSVSKGYYGECGKRGGYMEITG 316
Query: 362 FTSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAK 541
F++ VREQIYK+ASVNLCSNI+GQILASLVM+PPK GD+SY +Y AEK+GIL SLA+RAK
Sbjct: 317 FSAPVREQIYKIASVNLCSNITGQILASLVMNPPKVGDESYAAYKAEKDGILQSLARRAK 376
Query: 542 TLEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVV 721
LE+A N LEG++CN+AEGAMYLFP I+LP+KAI AA+AA APDAFY RLL +TGIVV
Sbjct: 377 ALEDAFNNLEGISCNKAEGAMYLFPQIHLPKKAIEAAKAANKAPDAFYALRLLESTGIVV 436
Query: 722 VPGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEFRD 859
VPGSGF QVPGTWH RCTILPQEDKIPA++ R FH++FM E+RD
Sbjct: 437 VPGSGFGQVPGTWHIRCTILPQEDKIPAVITRFKAFHEAFMAEYRD 482
>sp|Q54MJ7|ALAM_DICDI Probable alanine aminotransferase, mitochondrial
OS=Dictyostelium discoideum GN=gpt PE=3 SV=1
Length = 534
Score = 335 bits (858), Expect = 4e-091
Identities = 163/285 (57%), Positives = 204/285 (71%), Gaps = 1/285 (0%)
Frame = +2
Query: 5 GWGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLLA 184
GW LEIS+L+ +A SKGI RAL +INPGNPTGQ L N EIV FC ++ +VLLA
Sbjct: 250 GWSLEISQLEHSYNDAVSKGINPRALVIINPGNPTGQCLDRANMEEIVKFCLEKNVVLLA 309
Query: 185 DEVYQENVYVPDKK-FHSFKKVARSMGYGEKDICLVSFQSISKGYYGECGKRGGYMEVTG 361
DEVYQENVYV + K F SFKKV + MG D+ +VSF S+SKG+ GECGKRGGYME+ G
Sbjct: 310 DEVYQENVYVKESKPFISFKKVVKDMGGDYADLEMVSFHSVSKGFVGECGKRGGYMELNG 369
Query: 362 FTSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAK 541
T DV+ +IYKLAS+ LC N+ GQ++ L++ PP G+ S+D Y+ E++ I SL KRA
Sbjct: 370 VTQDVKAEIYKLASIGLCPNVIGQLVVDLMVRPPVAGEQSHDLYLKERDNIYESLKKRAN 429
Query: 542 TLEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVV 721
L ALN LEGVTCN +EGAMY FP I LP KA+ A + APDA+YC +LL ATGI V
Sbjct: 430 LLTNALNNLEGVTCNPSEGAMYAFPQIRLPAKAVEYANSIGKAPDAYYCIQLLEATGICV 489
Query: 722 VPGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEFR 856
VPGSGF Q GTWHFR T LP E+ I + R+ +FH+SFM++++
Sbjct: 490 VPGSGFGQKDGTWHFRTTFLPSEEAIEGVCKRIADFHQSFMNKYK 534
>sp|Q6GM82|ALAT2_XENLA Alanine aminotransferase 2 OS=Xenopus laevis GN=gpt2 PE=2
SV=1
Length = 540
Score = 294 bits (750), Expect = 1e-078
Identities = 146/284 (51%), Positives = 196/284 (69%), Gaps = 4/284 (1%)
Frame = +2
Query: 8 WGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLLAD 187
W L+I+EL++ L EAR K + L +INPGNPTGQV + + +++ F +E L L+AD
Sbjct: 258 WALDINELRRALAEAR-KHCDPKVLCIINPGNPTGQVQSRKCIEDVIRFAAEENLFLMAD 316
Query: 188 EVYQENVYVPDKKFHSFKKVARSMG--YGEKDICLVSFQSISKGYYGECGKRGGYMEVTG 361
EVYQ+NVY FHSFKKV MG Y E + L SF S SKGY GECG RGGYMEV
Sbjct: 317 EVYQDNVYAKGCAFHSFKKVLFEMGPKYSE-TLELASFHSTSKGYMGECGFRGGYMEVIN 375
Query: 362 FTSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAK 541
V++Q+ KL SV LC + GQ+L ++++PPKPG+ SY +I+EK+ +L++LA++A+
Sbjct: 376 MDPAVKQQLTKLVSVRLCPPVPGQVLLDVIVNPPKPGEPSYKQFISEKQAVLNNLAEKAR 435
Query: 542 TLEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVV 721
EE LN+ G+ CN +GAMY FP I++P+KAI A+A APD F+C +LL TGI V
Sbjct: 436 LTEEILNQAPGIRCNPVQGAMYSFPRIHIPEKAIKLAQAEGQAPDMFFCMKLLEETGICV 495
Query: 722 VPGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEF 853
VPGSGF Q GT HFR TILP DK+ +++ RL +FH+ FMDE+
Sbjct: 496 VPGSGFGQREGTHHFRMTILPPTDKLKSLLERLKDFHQKFMDEY 539
>sp|Q28DB5|ALAT2_XENTR Alanine aminotransferase 2 OS=Xenopus tropicalis GN=gpt2
PE=2 SV=1
Length = 524
Score = 288 bits (736), Expect = 6e-077
Identities = 144/284 (50%), Positives = 193/284 (67%), Gaps = 4/284 (1%)
Frame = +2
Query: 8 WGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLLAD 187
W L+I+EL++ L EAR K + L +INPGNPTGQV + + +++ F +E L L+AD
Sbjct: 242 WALDINELRRSLTEAR-KHCDPKVLCIINPGNPTGQVQSRKCIEDVIRFAAEENLFLMAD 300
Query: 188 EVYQENVYVPDKKFHSFKKVARSMG--YGEKDICLVSFQSISKGYYGECGKRGGYMEVTG 361
EVYQ+NVY FHSFKKV MG Y E + L SF S SKGY GECG RGGYMEV
Sbjct: 301 EVYQDNVYAKGCTFHSFKKVLFEMGPKYSE-TVELASFHSTSKGYMGECGFRGGYMEVIN 359
Query: 362 FTSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAK 541
V++Q+ KL SV LC + GQ L ++++PPKPG+ SY ++AEK+ +L +LA++A+
Sbjct: 360 MDPAVKQQLTKLVSVRLCPPVPGQALLDVIVNPPKPGEPSYKQFMAEKQAVLGNLAEKAR 419
Query: 542 TLEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVV 721
EE LN+ G+ CN +GAMY FP I++P+KAI A+A APD F+C +LL TGI V
Sbjct: 420 LTEEILNQSPGIRCNPVQGAMYSFPRIHIPEKAIKLAQAEGQAPDMFFCMKLLEETGICV 479
Query: 722 VPGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEF 853
VPGSGF Q GT HFR TILP DK+ +++ RL +FH+ F +E+
Sbjct: 480 VPGSGFGQREGTHHFRMTILPPTDKLKSLLERLKDFHQKFTEEY 523
>sp|Q8BGT5|ALAT2_MOUSE Alanine aminotransferase 2 OS=Mus musculus GN=Gpt2 PE=2
SV=1
Length = 522
Score = 287 bits (734), Expect = 1e-076
Identities = 137/283 (48%), Positives = 194/283 (68%), Gaps = 2/283 (0%)
Frame = +2
Query: 8 WGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLLAD 187
W L + EL++ L +A+ + L +INPGNPTGQV + + +++ F +E L LLAD
Sbjct: 240 WALNVDELRRALRQAKDH-CDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLAD 298
Query: 188 EVYQENVYVPDKKFHSFKKVARSMGYG-EKDICLVSFQSISKGYYGECGKRGGYMEVTGF 364
EVYQ+NVY PD +FHSFKKV MG+ ++ L SF S SKGY GECG RGGYMEV
Sbjct: 299 EVYQDNVYSPDCRFHSFKKVLYQMGHEYSSNVELASFHSTSKGYMGECGYRGGYMEVINL 358
Query: 365 TSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAKT 544
+++ Q+ KL SV LC +SGQ +V++PP+PG++S++ + EKE +L +LAK+AK
Sbjct: 359 HPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPEPGEESFEQFSREKEFVLGNLAKKAKL 418
Query: 545 LEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVVV 724
E+ N++ G+ CN +GAMY FP I +P KA+ AA++ K APD FYC +LL TGI VV
Sbjct: 419 TEDLFNQVPGIQCNPLQGAMYAFPRILIPAKAVEAAQSHKMAPDMFYCMKLLEETGICVV 478
Query: 725 PGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEF 853
PGSGF Q GT+HFR TILP DK+ +++++ +FH F++++
Sbjct: 479 PGSGFGQREGTYHFRMTILPPVDKLKTVLHKVKDFHLKFLEQY 521
>sp|Q6NYL5|ALAT2_DANRE Alanine aminotransferase 2-like OS=Danio rerio GN=gpt2l
PE=2 SV=2
Length = 549
Score = 286 bits (730), Expect = 3e-076
Identities = 143/284 (50%), Positives = 195/284 (68%), Gaps = 4/284 (1%)
Frame = +2
Query: 8 WGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLLAD 187
W L+ISEL++ L+ AR K R L +INPGNPTGQV + + +++ F +E L L+AD
Sbjct: 267 WSLDISELQRSLQAAR-KHCNPRVLCIINPGNPTGQVQSRQCIEDVIQFAAKENLFLMAD 325
Query: 188 EVYQENVYVPDKKFHSFKKVARSMG--YGEKDICLVSFQSISKGYYGECGKRGGYMEVTG 361
EVYQ+NVY +FHSFKKV MG Y +K + L SF S SK Y GECG RGGYMEV
Sbjct: 326 EVYQDNVYAKGCEFHSFKKVLFEMGPEYSKK-VELASFHSTSKCYMGECGFRGGYMEVIN 384
Query: 362 FTSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAK 541
+DV+ Q+ KL SV LC GQ L LV++PP+PG+ S+ +++ E+ +LS+LA++AK
Sbjct: 385 MDADVKAQLTKLVSVRLCPPAPGQALMDLVVNPPQPGEPSHQTFMQERTAVLSALAEKAK 444
Query: 542 TLEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVV 721
E+ LN + G++CN +GAMY FP I LP++AI+ A+A APD FYC +LL TGI +
Sbjct: 445 LTEQILNTVPGISCNPVQGAMYSFPRITLPERAISEAKAKGQAPDMFYCMKLLEETGICL 504
Query: 722 VPGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEF 853
VPGSGF Q GT+HFR TILP DK+ ++N+L +FH+ F ++
Sbjct: 505 VPGSGFGQREGTYHFRMTILPPTDKLKLMLNKLKDFHQRFTQQY 548
>sp|Q8TD30|ALAT2_HUMAN Alanine aminotransferase 2 OS=Homo sapiens GN=GPT2 PE=1
SV=1
Length = 523
Score = 280 bits (716), Expect = 1e-074
Identities = 135/283 (47%), Positives = 193/283 (68%), Gaps = 2/283 (0%)
Frame = +2
Query: 8 WGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLLAD 187
W L ++EL++ ++EA+ + L +INPGNPTGQV + + +++ F +E L LLAD
Sbjct: 241 WALNVNELRRAVQEAKDH-CDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLAD 299
Query: 188 EVYQENVYVPDKKFHSFKKVARSMG-YGEKDICLVSFQSISKGYYGECGKRGGYMEVTGF 364
EVYQ+NVY PD +FHSFKKV MG ++ L SF S SKGY GECG RGGYMEV
Sbjct: 300 EVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINL 359
Query: 365 TSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAKT 544
+++ Q+ KL SV LC +SGQ +V++PP G++S++ + EKE +L +LAK+AK
Sbjct: 360 HPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKL 419
Query: 545 LEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVVV 724
E+ N++ G+ CN +GAMY FP I +P KA+ AA+A + APD FYC +LL TGI VV
Sbjct: 420 TEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVV 479
Query: 725 PGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEF 853
PGSGF Q GT+HFR TILP +K+ ++ ++ +FH +F++++
Sbjct: 480 PGSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKY 522
>sp|A4IFH5|ALAT1_BOVIN Alanine aminotransferase 1 OS=Bos taurus GN=GPT PE=1
SV=1
Length = 496
Score = 273 bits (696), Expect = 2e-072
Identities = 138/284 (48%), Positives = 183/284 (64%), Gaps = 4/284 (1%)
Frame = +2
Query: 8 WGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLLAD 187
W L+++EL++ L +AR RAL VINPGNPTGQV E +++ F +E L LLAD
Sbjct: 214 WALDVAELRRALRQARDH-CRPRALCVINPGNPTGQVQTRECIEDVIRFAYEEKLFLLAD 272
Query: 188 EVYQENVYVPDKKFHSFKKVARSMG--YGEKDICLVSFQSISKGYYGECGKRGGYMEVTG 361
EVYQ+NVY +FHSFKKV MG Y + L SF SISKGY GECG RGGY+EV
Sbjct: 273 EVYQDNVYAESSQFHSFKKVLTEMGPPYAAQQE-LASFHSISKGYMGECGFRGGYVEVVN 331
Query: 362 FTSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAK 541
+ V++Q+ KL SV LC GQ+L + +SPP P D S+ + AE+ +L+ LA +AK
Sbjct: 332 MDAAVKQQMQKLRSVRLCPPTPGQVLLDVAVSPPAPSDPSFPRFQAERRAVLAELAAKAK 391
Query: 542 TLEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVV 721
E+ N+ G+ CN +GAMY FP + LP +A+ A+ APD F+C RLL TGI V
Sbjct: 392 LTEQVFNEAPGIRCNPVQGAMYSFPRVQLPPRAVQRAQELGLAPDMFFCLRLLEETGICV 451
Query: 722 VPGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEF 853
VPGSGF Q GT+HFR TILP +K+ ++ +L++FH F E+
Sbjct: 452 VPGSGFGQREGTYHFRMTILPPMEKLRPLLEKLSQFHAKFTREY 495
>sp|P24298|ALAT1_HUMAN Alanine aminotransferase 1 OS=Homo sapiens GN=GPT PE=1
SV=3
Length = 496
Score = 270 bits (690), Expect = 1e-071
Identities = 140/285 (49%), Positives = 184/285 (64%), Gaps = 6/285 (2%)
Frame = +2
Query: 8 WGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLLAD 187
W L+++EL + L +AR RAL VINPGNPTGQV E ++ F +E L LLAD
Sbjct: 214 WALDVAELHRALGQARDH-CRPRALCVINPGNPTGQVQTRECIEAVIRFAFEERLFLLAD 272
Query: 188 EVYQENVYVPDKKFHSFKKVARSMG---YGEKDICLVSFQSISKGYYGECGKRGGYMEVT 358
EVYQ+NVY +FHSFKKV MG G+++ L SF S SKGY GECG RGGY+EV
Sbjct: 273 EVYQDNVYAAGSQFHSFKKVLMEMGPPYAGQQE--LASFHSTSKGYMGECGFRGGYVEVV 330
Query: 359 GFTSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRA 538
+ V++Q+ KL SV LC + GQ L LV+SPP P D S+ + AEK+ +L+ LA +A
Sbjct: 331 NMDAAVQQQMLKLMSVRLCPPVPGQALLDLVVSPPAPTDPSFAQFQAEKQAVLAELAAKA 390
Query: 539 KTLEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIV 718
K E+ N+ G++CN +GAMY FP + LP +A+ A+ APD F+C RLL TGI
Sbjct: 391 KLTEQVFNEAPGISCNPVQGAMYSFPRVQLPPRAVERAQELGLAPDMFFCLRLLEETGIC 450
Query: 719 VVPGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEF 853
VVPGSGF Q GT+HFR TILP +K+ ++ +L+ FH F E+
Sbjct: 451 VVPGSGFGQREGTYHFRMTILPPLEKLRLLLEKLSRFHAKFTLEY 495
>sp|Q8QZR5|ALAT1_MOUSE Alanine aminotransferase 1 OS=Mus musculus GN=Gpt PE=2
SV=3
Length = 496
Score = 270 bits (688), Expect = 2e-071
Identities = 138/284 (48%), Positives = 183/284 (64%), Gaps = 4/284 (1%)
Frame = +2
Query: 8 WGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLLAD 187
W L+I+EL++ L +AR + R L VINPGNPTGQV E ++ F +EGL L+AD
Sbjct: 214 WALDIAELRRALCQARDR-CCPRVLCVINPGNPTGQVQTRECIEAVIRFAFEEGLFLMAD 272
Query: 188 EVYQENVYVPDKKFHSFKKVARSMG--YGEKDICLVSFQSISKGYYGECGKRGGYMEVTG 361
EVYQ+NVY +FHSFKKV MG Y + L SF S+SKGY GECG RGGY+EV
Sbjct: 273 EVYQDNVYAEGSQFHSFKKVLTEMGPPYATQQE-LASFHSVSKGYMGECGFRGGYVEVVN 331
Query: 362 FTSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAK 541
++V++Q+ KL SV LC + GQ L +V+SPP P + S+ + AE++ +L+ LA +AK
Sbjct: 332 MDAEVQKQMAKLMSVRLCPPVPGQALMGMVVSPPTPSEPSFKQFQAERQEVLAELAAKAK 391
Query: 542 TLEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVV 721
E+ N+ G+ CN +GAMY FP I LP KA+ A+ APD F+C LL TGI V
Sbjct: 392 LTEQVFNEAPGIRCNPVQGAMYSFPQIQLPLKAVQRAQDLGLAPDMFFCLCLLEETGICV 451
Query: 722 VPGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEF 853
VPGSGF Q GT+HFR TILP +K+ ++ +L FH F E+
Sbjct: 452 VPGSGFGQQEGTYHFRMTILPPMEKLRVLLEKLRHFHAKFTHEY 495
>sp|P25409|ALAT1_RAT Alanine aminotransferase 1 OS=Rattus norvegicus GN=Gpt PE=1
SV=2
Length = 496
Score = 269 bits (687), Expect = 3e-071
Identities = 137/284 (48%), Positives = 184/284 (64%), Gaps = 4/284 (1%)
Frame = +2
Query: 8 WGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLLAD 187
W L+I+EL++ L +AR + R L VINPGNPTGQV E ++ F +EGL L+AD
Sbjct: 214 WALDIAELRRALCQARDR-CCPRVLCVINPGNPTGQVQTRECIEAVIRFAFKEGLFLMAD 272
Query: 188 EVYQENVYVPDKKFHSFKKVARSMG--YGEKDICLVSFQSISKGYYGECGKRGGYMEVTG 361
EVYQ+NVY +FHSFKKV MG Y + L SF S+SKGY GECG RGGY+EV
Sbjct: 273 EVYQDNVYAEGSQFHSFKKVLMEMGPPYSTQQE-LASFHSVSKGYMGECGFRGGYVEVVN 331
Query: 362 FTSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAK 541
++V++Q+ KL SV LC + GQ L +V+SPP P + S+ + AE++ +L+ LA +AK
Sbjct: 332 MDAEVQKQMGKLMSVRLCPPVPGQALMDMVVSPPTPSEPSFKQFQAERQEVLAELAAKAK 391
Query: 542 TLEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVV 721
E+ N+ G+ CN +GAMY FP + LP KA+ A+ APD F+C LL TGI V
Sbjct: 392 LTEQVFNEAPGIRCNPVQGAMYSFPQVQLPLKAVQRAQELGLAPDMFFCLCLLEETGICV 451
Query: 722 VPGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDEF 853
VPGSGF Q GT+HFR TILP +K+ ++ +L+ FH F E+
Sbjct: 452 VPGSGFGQQEGTYHFRMTILPPMEKLRLLLEKLSHFHAKFTHEY 495
>sp|P52893|ALAM_YEAST Probable alanine aminotransferase, mitochondrial
OS=Saccharomyces cerevisiae GN=ALT1 PE=1 SV=1
Length = 592
Score = 247 bits (629), Expect = 1e-064
Identities = 132/281 (46%), Positives = 179/281 (63%), Gaps = 12/281 (4%)
Frame = +2
Query: 26 ELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLLADEVYQEN 205
E++ ++EA I L VINPGNPTG VL+ E+ +I + + G V++ADEVYQEN
Sbjct: 315 EIETVVKEAIQNEIKPTVLVVINPGNPTGAVLSPESIAQIFEVAAKYGTVVIADEVYQEN 374
Query: 206 VYVPDKKFHSFKKVARSMGY---GEKD-ICLVSFQSISKGYYGECGKRGGYMEVTGFTSD 373
++ P KFHS KK+ R + G+ D + L S S SKG GECG+RGGYME+TGF+ +
Sbjct: 375 IF-PGTKFHSMKKILRHLQREHPGKFDNVQLASLHSTSKGVSGECGQRGGYMELTGFSHE 433
Query: 374 VREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAKTLEE 553
+R+ I KLAS++LC ++GQ L L++ PP G++S++S AE+ I L RA TL E
Sbjct: 434 MRQVILKLASISLCPVVTGQALVDLMVRPPVEGEESFESDQAERNSIHEKLITRAMTLYE 493
Query: 554 ALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVVVPGS 733
N LEG+ C + +GAMYLFP I+LP KA+ A + PD FYCK+LL +TGI VPGS
Sbjct: 494 TFNSLEGIECQKPQGAMYLFPKIDLPFKAVQEARHLELTPDEFYCKKLLESTGICTVPGS 553
Query: 734 GFRQVPGTWHFRCTILPQEDKIPAI--VNRLTEFHKSFMDE 850
GF Q PGT+H R T L P + + + FHK F D+
Sbjct: 554 GFGQEPGTYHLRTTFL-----APGLEWIKKWESFHKEFFDQ 589
>sp|Q10334|ALAT_SCHPO Putative alanine aminotransferase OS=Schizosaccharomyces
pombe GN=SPBC582.08 PE=2 SV=1
Length = 505
Score = 245 bits (625), Expect = 4e-064
Identities = 121/287 (42%), Positives = 175/287 (60%), Gaps = 10/287 (3%)
Frame = +2
Query: 2 SGWGLEISELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLL 181
+ W ++ + KK +EA KGI VR VINPGNPTG ++E + +++ F K +G+VLL
Sbjct: 221 NNWDIDFDQFKKSFDEASKKGINVRLCVVINPGNPTGACISENSMEKVLRFAKAKGIVLL 280
Query: 182 ADEVYQENVYVPDKKFHSFKKVARSMGYGEKD-----ICLVSFQSISKGYYGECGKRGGY 346
ADEVYQ N+Y KFHSF++ + E D + L+S S+SKG +GECG+RGGY
Sbjct: 281 ADEVYQNNIY--QNKFHSFRRKLGELREKEPDNHWDQVSLISVNSVSKGQFGECGQRGGY 338
Query: 347 MEVTGFTSDVREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSL 526
++V ++QI KLA++++C ++GQ+L ++++PPKPGD SYD +I E + I +L
Sbjct: 339 LDVVNIPEPAKDQILKLATIDICPPVAGQLLVDMLVNPPKPGDPSYDLFIKEVDEIHEAL 398
Query: 527 AKRAKTLEEALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNA 706
+ + L E +++ V+C GAMYL P ++LP+K I A+A K PD FY LL
Sbjct: 399 RLQCRQLYEGTKRMKRVSCLEPHGAMYLHPSVSLPEKLITTAKAQKIQPDEFYAIELLKR 458
Query: 707 TGIVVVPGSGFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMD 847
+GI VVPGSGF Q G +H R T L K + R + H MD
Sbjct: 459 SGICVVPGSGFGQPEGDYHIRITFLA---KGTEYIERFVKAHNEIMD 502
>sp|P52892|ALAT_YEAST Probable alanine aminotransferase OS=Saccharomyces
cerevisiae GN=ALT2 PE=1 SV=1
Length = 507
Score = 240 bits (611), Expect = 2e-062
Identities = 124/279 (44%), Positives = 176/279 (63%), Gaps = 8/279 (2%)
Frame = +2
Query: 26 ELKKQLEEARSKGITVRALAVINPGNPTGQVLAEENQREIVDFCKQEGLVLLADEVYQEN 205
E++K +++A K I L VINPGNPTG VL+EE I + G+ +++DEVYQEN
Sbjct: 230 EIEKVVQDALKKQIRPSVLIVINPGNPTGAVLSEETIARICLIAAKYGITIISDEVYQEN 289
Query: 206 VYVPDKKFHSFKKVARSMGY---GEKD-ICLVSFQSISKGYYGECGKRGGYMEVTGFTSD 373
++ D KFHS KKV R + + G+ D + L S SISKG+ ECG+RGGYME+ GF+ +
Sbjct: 290 IF-NDVKFHSMKKVLRKLQHLYPGKFDNVQLASLHSISKGFMDECGQRGGYMEIIGFSQE 348
Query: 374 VREQIYKLASVNLCSNISGQILASLVMSPPKPGDDSYDSYIAEKEGILSSLAKRAKTLEE 553
+R+ ++KL S+++CS ++GQ + L++ PP+PGD+SY+ E+ I + RA L E
Sbjct: 349 IRDALFKLMSISICSVVTGQAVVDLMVKPPQPGDESYEQDHDERLKIFHEMRTRANLLYE 408
Query: 554 ALNKLEGVTCNRAEGAMYLFPCINLPQKAIAAAEAAKTAPDAFYCKRLLNATGIVVVPGS 733
+LEG+ C + +GAMYLFP + LP+KA+ +E PD FYC LL +TGI VPGS
Sbjct: 409 TFKELEGIECQKPQGAMYLFPRLVLPKKALCESERLGIEPDEFYCTSLLESTGICTVPGS 468
Query: 734 GFRQVPGTWHFRCTILPQEDKIPAIVNRLTEFHKSFMDE 850
GF Q PGT+H R T L K + EFH+ F +
Sbjct: 469 GFGQRPGTYHVRTTFLAPGTK---WIQDWKEFHQDFFSK 504
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,771,599,260
Number of Sequences: 518415
Number of Extensions: 58771599260
Number of Successful Extensions: 389091298
Number of sequences better than 0.0: 0
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