BLASTX 7.6.2
Query= UN14393 /QuerySize=1320
(1319 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P54001|P4HA1_RAT Prolyl 4-hydroxylase subunit alpha-1 OS=Ratt... 103 3e-021
sp|Q5ZLK5|P4HA2_CHICK Prolyl 4-hydroxylase subunit alpha-2 OS=Ga... 102 9e-021
sp|Q60716|P4HA2_MOUSE Prolyl 4-hydroxylase subunit alpha-2 OS=Mu... 100 4e-020
sp|Q60715|P4HA1_MOUSE Prolyl 4-hydroxylase subunit alpha-1 OS=Mu... 99 5e-020
sp|P16924|P4HA1_CHICK Prolyl 4-hydroxylase subunit alpha-1 OS=Ga... 99 8e-020
sp|P13674|P4HA1_HUMAN Prolyl 4-hydroxylase subunit alpha-1 OS=Ho... 97 3e-019
sp|Q5RAG8|P4HA1_PONAB Prolyl 4-hydroxylase subunit alpha-1 OS=Po... 97 3e-019
sp|Q10576|P4HA1_CAEEL Prolyl 4-hydroxylase subunit alpha-1 OS=Ca... 95 1e-018
sp|Q1RMU3|P4HA1_BOVIN Prolyl 4-hydroxylase subunit alpha-1 OS=Bo... 94 2e-018
>sp|P54001|P4HA1_RAT Prolyl 4-hydroxylase subunit alpha-1 OS=Rattus norvegicus
GN=P4ha1 PE=2 SV=2
Length = 534
Score = 103 bits (256), Expect = 3e-021
Identities = 59/154 (38%), Positives = 85/154 (55%), Gaps = 9/154 (5%)
Frame = +3
Query: 480 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDQV 659
+PR + +H+ +++ E E + LAKP + ++TV D +TG ++ R S +L D V
Sbjct: 334 KPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYEDPV 393
Query: 660 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYESHYDYFL----DEFNTKNGGQRIATV 827
V RI RI D T + V E LQV +Y VG +YE H+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATW 453
Query: 828 LMYLSDVDDGGETVFPAAKGNI-----SAVPWWD 914
L Y+SDV GG TVFP ++ +AV W++
Sbjct: 454 LFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN 487
>sp|Q5ZLK5|P4HA2_CHICK Prolyl 4-hydroxylase subunit alpha-2 OS=Gallus gallus
GN=P4HA2 PE=2 SV=1
Length = 534
Score = 102 bits (252), Expect = 9e-021
Identities = 54/136 (39%), Positives = 84/136 (61%), Gaps = 3/136 (2%)
Frame = +3
Query: 477 WE-PRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHD 653
W+ P V Y++ +++EE E + LAKP + ++TV D KTG + R S ++L+ D
Sbjct: 334 WDSPHIVRYYDVMSDEEIEKIKQLAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 393
Query: 654 QVVERIEQRISDFTFIPVENGEGLQVLHYQVGQKYESHYDYFLDEFNT--KNGGQRIATV 827
VV ++ QR+ T + V+ E LQV +Y +G +YE H+D+ F++ K+ G R+AT
Sbjct: 394 PVVAKVNQRMQQITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSTLKSEGNRLATF 453
Query: 828 LMYLSDVDDGGETVFP 875
L Y+SDV+ GG TVFP
Sbjct: 454 LNYMSDVEAGGATVFP 469
>sp|Q60716|P4HA2_MOUSE Prolyl 4-hydroxylase subunit alpha-2 OS=Mus musculus
GN=P4ha2 PE=2 SV=1
Length = 537
Score = 100 bits (247), Expect = 4e-020
Identities = 58/158 (36%), Positives = 89/158 (56%), Gaps = 10/158 (6%)
Frame = +3
Query: 477 WE-PRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHD 653
W+ P V Y++ +++EE E + +AKP + ++TV D KTG + R S ++L+ D
Sbjct: 335 WDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 394
Query: 654 QVVERIEQRISDFTFIPVENGEGLQVLHYQVGQKYESHYDYFL----DEFNTKNGGQRIA 821
VV R+ +R+ T + V+ E LQV +Y +G +YE H+D+ D F G R+A
Sbjct: 395 PVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDDEDAFKRLGTGNRVA 454
Query: 822 TVLMYLSDVDDGGETVFPAAKGNI-----SAVPWWDQL 920
T L Y+SDV+ GG TVFP I +AV W++ L
Sbjct: 455 TFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLL 492
>sp|Q60715|P4HA1_MOUSE Prolyl 4-hydroxylase subunit alpha-1 OS=Mus musculus
GN=P4ha1 PE=2 SV=2
Length = 534
Score = 99 bits (246), Expect = 5e-020
Identities = 57/154 (37%), Positives = 83/154 (53%), Gaps = 9/154 (5%)
Frame = +3
Query: 480 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDQV 659
+PR + +H+ +++ E E + LAKP + ++T+ + TG + R S +L D V
Sbjct: 334 KPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPVTGALETVHYRISKSAWLSGYEDPV 393
Query: 660 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYESHYDYFL----DEFNTKNGGQRIATV 827
V RI RI D T + V E LQV +Y VG +YE H+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATW 453
Query: 828 LMYLSDVDDGGETVFPAAKGNI-----SAVPWWD 914
L Y+SDV GG TVFP ++ +AV W++
Sbjct: 454 LFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN 487
>sp|P16924|P4HA1_CHICK Prolyl 4-hydroxylase subunit alpha-1 OS=Gallus gallus
GN=P4HA1 PE=1 SV=1
Length = 516
Score = 99 bits (244), Expect = 8e-020
Identities = 59/154 (38%), Positives = 83/154 (53%), Gaps = 9/154 (5%)
Frame = +3
Query: 480 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDQV 659
+PR V + + +++EE E + LAKP + ++TV D +TG + R S +L V
Sbjct: 316 KPRIVRFLDIISDEEIETVKELAKPRLSRATVHDPETGKLTTAHYRVSKSAWLSGYESPV 375
Query: 660 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYESHYDYFL----DEFNTKNGGQRIATV 827
V RI RI D T + V E LQV +Y VG +YE H+D+ D F G RIAT
Sbjct: 376 VSRINTRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATW 435
Query: 828 LMYLSDVDDGGETVFPAAKGNI-----SAVPWWD 914
L Y+SDV GG TVFP ++ +AV W++
Sbjct: 436 LFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN 469
Score = 54 bits (128), Expect = 2e-006
Identities = 23/47 (48%), Positives = 29/47 (61%)
Frame = +3
Query: 939 GLSVLPKKRDALLFWNMRPDASLDPSSLHGGCPVVKGNKWSSTKWFH 1079
G SV PKK A+ ++N+ P D S+ H CPV+ GNKW S KW H
Sbjct: 454 GASVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWLH 500
>sp|P13674|P4HA1_HUMAN Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens
GN=P4HA1 PE=1 SV=2
Length = 534
Score = 97 bits (239), Expect = 3e-019
Identities = 56/154 (36%), Positives = 83/154 (53%), Gaps = 9/154 (5%)
Frame = +3
Query: 480 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDQV 659
+PR + +H+ +++ E E + LAKP + ++T+ + TG + R S +L + V
Sbjct: 334 KPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPV 393
Query: 660 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYESHYDYFL----DEFNTKNGGQRIATV 827
V RI RI D T + V E LQV +Y VG +YE H+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATW 453
Query: 828 LMYLSDVDDGGETVFPAAKGNI-----SAVPWWD 914
L Y+SDV GG TVFP ++ +AV W++
Sbjct: 454 LFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN 487
>sp|Q5RAG8|P4HA1_PONAB Prolyl 4-hydroxylase subunit alpha-1 OS=Pongo abelii
GN=P4HA1 PE=2 SV=1
Length = 534
Score = 97 bits (239), Expect = 3e-019
Identities = 56/154 (36%), Positives = 83/154 (53%), Gaps = 9/154 (5%)
Frame = +3
Query: 480 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDQV 659
+PR + +H+ +++ E E + LAKP + ++T+ + TG + R S +L + V
Sbjct: 334 KPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPV 393
Query: 660 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYESHYDYFL----DEFNTKNGGQRIATV 827
V RI RI D T + V E LQV +Y VG +YE H+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATW 453
Query: 828 LMYLSDVDDGGETVFPAAKGNI-----SAVPWWD 914
L Y+SDV GG TVFP ++ +AV W++
Sbjct: 454 LFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN 487
>sp|Q10576|P4HA1_CAEEL Prolyl 4-hydroxylase subunit alpha-1 OS=Caenorhabditis
elegans GN=dpy-18 PE=1 SV=2
Length = 559
Score = 95 bits (234), Expect = 1e-018
Identities = 53/148 (35%), Positives = 80/148 (54%), Gaps = 4/148 (2%)
Frame = +3
Query: 462 VEVISWEPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLK 641
VE+ + P AV++ + ++++E + LAKP + ++TV D TG + R S +LK
Sbjct: 321 VEIKRFNPLAVLFKDVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKSAWLK 380
Query: 642 RGHDQVVERIEQRISDFTFIPVENGEGLQVLHYQVGQKYESHYDYFLDE----FNTKNGG 809
VVE + +RI T + +E E LQ+ +Y +G Y+ H+D+ E F + G
Sbjct: 381 EWEGDVVETVNKRIGYMTNLEMETAEELQIANYGIGGHYDPHFDHAKKEESKSFESLGTG 440
Query: 810 QRIATVLMYLSDVDDGGETVFPAAKGNI 893
RIATVL Y+S GG TVF AK I
Sbjct: 441 NRIATVLFYMSQPSHGGGTVFTEAKSTI 468
>sp|Q1RMU3|P4HA1_BOVIN Prolyl 4-hydroxylase subunit alpha-1 OS=Bos taurus
GN=P4HA1 PE=1 SV=1
Length = 534
Score = 94 bits (232), Expect = 2e-018
Identities = 53/142 (37%), Positives = 77/142 (54%), Gaps = 4/142 (2%)
Frame = +3
Query: 480 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDQV 659
+PR + +H+ +++ E E + LAKP + ++T+ + TG + R S +L + V
Sbjct: 334 KPRIIRFHDIISDAEIEVVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPV 393
Query: 660 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYESHYDYFL----DEFNTKNGGQRIATV 827
V RI RI D T + V E LQV +Y VG +YE H+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATW 453
Query: 828 LMYLSDVDDGGETVFPAAKGNI 893
L Y+SDV GG TVFP ++
Sbjct: 454 LFYMSDVLAGGATVFPEVGASV 475
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,771,599,260
Number of Sequences: 518415
Number of Extensions: 58771599260
Number of Successful Extensions: 389091298
Number of sequences better than 0.0: 0
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