BLASTX 7.6.2
Query= UN14468 /QuerySize=1303
(1302 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9LD90|DKC1_ARATH H/ACA ribonucleoprotein complex subunit 4 O... 531 5e-150
sp|Q54T81|DKC1_DICDI Probable H/ACA ribonucleoprotein complex su... 360 1e-098
sp|Q5ZJH9|DKC1_CHICK H/ACA ribonucleoprotein complex subunit 4 O... 339 5e-092
sp|O13473|CBF5_KLULA Centromere/microtubule-binding protein CBF5... 337 2e-091
sp|O14007|CBF5_SCHPO H/ACA ribonucleoprotein complex subunit 4 O... 334 1e-090
sp|P40615|DKC1_RAT H/ACA ribonucleoprotein complex subunit 4 OS=... 333 2e-090
sp|P33322|CBF5_YEAST H/ACA ribonucleoprotein complex subunit 4 O... 331 9e-090
sp|O60832|DKC1_HUMAN H/ACA ribonucleoprotein complex subunit 4 O... 327 1e-088
sp|O43101|CBF5_CANAL Centromere/microtubule-binding protein CBF5... 323 3e-087
sp|O43100|CBF5_EMENI Centromere/microtubule-binding protein CBF5... 320 2e-086
sp|O43102|CBF5_ASPFU Centromere/microtubule-binding protein cbf5... 317 1e-085
sp|Q9ESX5|DKC1_MOUSE H/ACA ribonucleoprotein complex subunit 4 O... 317 2e-085
sp|O44081|DKC1_DROME H/ACA ribonucleoprotein complex subunit 4 O... 309 3e-083
sp|O17919|DKC1_CAEEL Putative H/ACA ribonucleoprotein complex su... 282 5e-075
sp|Q60YA8|DKC1_CAEBR Putative H/ACA ribonucleoprotein complex su... 275 6e-073
sp|Q980C3|TRUB_SULSO Probable tRNA pseudouridine synthase B OS=S... 139 5e-032
sp|Q8TZ08|TRUB_METKA Probable tRNA pseudouridine synthase B OS=M... 136 3e-031
sp|Q57612|TRUB_METJA Probable tRNA pseudouridine synthase B OS=M... 132 5e-030
sp|B1L793|TRUB_KORCO Probable tRNA pseudouridine synthase B OS=K... 126 4e-028
sp|Q7LWY0|TRUB_PYRFU Probable tRNA pseudouridine synthase B OS=P... 124 2e-027
>sp|Q9LD90|DKC1_ARATH H/ACA ribonucleoprotein complex subunit 4 OS=Arabidopsis
thaliana GN=NAP57 PE=1 SV=1
Length = 565
Score = 531 bits (1367), Expect = 5e-150
Identities = 284/356 (79%), Positives = 310/356 (87%), Gaps = 22/356 (6%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RTMCVHLGLLLGVGGHMQELRRVRSGILGEN+NMVTMHDVMDAQ++YDN +DESYLRRVI
Sbjct: 218 RTMCVHLGLLLGVGGHMQELRRVRSGILGENNNMVTMHDVMDAQFVYDNSRDESYLRRVI 277
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
MPLE+ILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFEND+DVGTEVVLMTTKGEAIAVG
Sbjct: 278 MPLEMILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDIDVGTEVVLMTTKGEAIAVG 337
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE
Sbjct: 338 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 397
Query: 761 KTPVEWSRNVVLPTGGDAMVAGAAAAPEKVEA-----ESGEVRKRKLDESSDSPAPVSTK 597
KTPVEWSRNVVLPTGGDA++AGAAAAPE+++A E+GE RKRK D+SSDSPAPV+TK
Sbjct: 398 KTPVEWSRNVVLPTGGDAIIAGAAAAPEEIKADAENGEAGEARKRKHDDSSDSPAPVTTK 457
Query: 596 KAKTKEV---EVEEKVKSEKKEKKKKKDKEEDKEELATPKSEKKKKKKSKETDEAAAAVN 426
K+KTKEV E EEKVKS K KKKKKDKEE+KEE A SEKK+KKK K+ E
Sbjct: 458 KSKTKEVEGEEAEEKVKSSK--KKKKKDKEEEKEEEA--GSEKKEKKKKKDKKEEVI--- 510
Query: 425 GEDESPAEKSEKKKKKKKDKETDEAGGGE---SAEKSE-KKKKKEKKKKSKDSDDE 270
E A +KKKKKK K+T+ A E +AEKSE KKKKK+KKKK+KDS+D+
Sbjct: 511 ---EEVASPKSEKKKKKKSKDTEAAVDAEDESAAEKSEKKKKKKDKKKKNKDSEDD 563
>sp|Q54T81|DKC1_DICDI Probable H/ACA ribonucleoprotein complex subunit 4
OS=Dictyostelium discoideum GN=nola4 PE=1 SV=1
Length = 540
Score = 360 bits (923), Expect = 1e-098
Identities = 184/332 (55%), Positives = 234/332 (70%), Gaps = 15/332 (4%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVH+GLL+GVGGHMQELRRVRSGI+ E VTMHDV DAQ+ YDN KDESYLRRVI
Sbjct: 211 RTLCVHIGLLMGVGGHMQELRRVRSGIMSEKKGQVTMHDVKDAQYEYDNSKDESYLRRVI 270
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE ILT+YKR+VVKDSA+NAICYGAKLMIPGLLR+E D++ EVVL+TTKGEAIA+G
Sbjct: 271 QPLEAILTNYKRIVVKDSAINAICYGAKLMIPGLLRYEQDIESNEEVVLITTKGEAIAIG 330
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA+MTT+ MATCDHGVVA IKRV+MDRD YP +WGLGP+A +KK++I DGKLDK GKPNE
Sbjct: 331 IAQMTTASMATCDHGVVATIKRVIMDRDVYPVRWGLGPKAKVKKEMIKDGKLDKFGKPNE 390
Query: 761 KTPVEWSRNVVLPTGGDAMVAGAAAAPEKVEAESGEVRKRKLDESSDSPAPVSTK---KA 591
KTP +W+ TG A + V +D + A V+ K ++
Sbjct: 391 KTPSDWTNTYTYYTGQVA-----------TTTTTSPVESMNVDTPKKATASVAVKAEVES 439
Query: 590 KTKEVEVEEKVKSEKKEKKKKKDKEEDKEELATPKSEKKKKKKSKETDEAAAAVNGEDES 411
E V +K K +KKEKKK +E +EE ++ K +KK+KK+ KE E ++ + D+
Sbjct: 440 SEDEKPVPKKEKKDKKEKKKDSSDDESEEEKSS-KKDKKEKKEKKEKKEKKSSKDDSDDE 498
Query: 410 PAEKSEKKKKKKKDKETDEAGGGESAEKSEKK 315
++K +K KK+KK + D ES++K +KK
Sbjct: 499 SSKKEKKDKKRKKSSDKDSDSEKESSDKKDKK 530
>sp|Q5ZJH9|DKC1_CHICK H/ACA ribonucleoprotein complex subunit 4 OS=Gallus gallus
GN=DKC1 PE=2 SV=1
Length = 516
Score = 339 bits (867), Expect = 5e-092
Identities = 175/294 (59%), Positives = 221/294 (75%), Gaps = 9/294 (3%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVHLGLLLGVGG MQELRRVRSGILGE DNMVTMHDV+DAQW YDN KD+SYLRRVI
Sbjct: 225 RTLCVHLGLLLGVGGQMQELRRVRSGILGEMDNMVTMHDVLDAQWQYDNNKDDSYLRRVI 284
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
+PLE +LTS+KRLV+KDSAVNAICYGAK+M+PG+LR+E+ +++ E+V++TTKGEAI +
Sbjct: 285 LPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIELKQEIVVITTKGEAICLA 344
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA MTT+V++TCDHGVVAKIKRV+M+RDTYPRKWGLGP+AS KK +I G LDKHGKPNE
Sbjct: 345 IALMTTAVISTCDHGVVAKIKRVIMERDTYPRKWGLGPKASQKKMMIQKGLLDKHGKPNE 404
Query: 761 KTPVEWSRNVVLPTGGDAMVAGAAAAPEKV-EAESGEVRKRKLDESSDSPAPVSTKKAKT 585
TP W + V ++ AA P+ V E E RKR+ + +++ +P +
Sbjct: 405 CTPDSWKKEYV--DYRESSKKEAAKVPQAVSEVERAPKRKRESESENEAVSPPPSPATPP 462
Query: 584 KEVEVEEKVKSEKKEKKKKKDKEEDKEELATPKSE-----KKKKKKSKETDEAA 438
E E+ +K K +KK++KK K+ E EE SE KKKKKK KE +E++
Sbjct: 463 PE-ELSKKEKKKKKKEKKAKEAAESGEEQVEVISESSAKKKKKKKKQKEVEESS 515
>sp|O13473|CBF5_KLULA Centromere/microtubule-binding protein CBF5
OS=Kluyveromyces lactis GN=CBF5 PE=3 SV=1
Length = 474
Score = 337 bits (862), Expect = 2e-091
Identities = 170/282 (60%), Positives = 211/282 (74%), Gaps = 9/282 (3%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVHLG+LLGVGGHMQELRRVRSG L ENDN+VT+HDVMDAQW+YDN +DESYLR++I
Sbjct: 196 RTLCVHLGMLLGVGGHMQELRRVRSGALSENDNLVTLHDVMDAQWVYDNTRDESYLRKII 255
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE +L YKR+VVKDSAVNA+CYGAKLMIPGLLR+E +++ EVVL+TTKGEAIAV
Sbjct: 256 QPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIELYDEVVLITTKGEAIAVA 315
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA+M+T +ATCDHGVVAK+KR +M+RD YPR+WGLGP A KK++ ADGKLDK+G+ NE
Sbjct: 316 IAQMSTVDLATCDHGVVAKVKRCIMERDLYPRRWGLGPIAQKKKQMKADGKLDKYGRANE 375
Query: 761 KTPVEWSRNVVLPTGGDAMVAGAAAAPEK---VEAESGEVRKRKLDESSDSPAPVSTKKA 591
TP W + V + A A+ + EK E E EV ++K + +S P K
Sbjct: 376 NTPETWKKTYVSLENAEPTTAPASKSEEKPLIKEVEKKEV-EQKEESKEESKTPEEKKDK 434
Query: 590 KTKEVEVEEKVKSEKKEKKKKKDKEEDKEELATPKSEKKKKK 465
K K+ + ++K K EKKEKK+KK K +D E SEKKKKK
Sbjct: 435 KEKKEKKDKKEKKEKKEKKEKKRKADDDE-----SSEKKKKK 471
>sp|O14007|CBF5_SCHPO H/ACA ribonucleoprotein complex subunit 4
OS=Schizosaccharomyces pombe GN=cbf5 PE=2 SV=1
Length = 474
Score = 334 bits (854), Expect = 1e-090
Identities = 168/273 (61%), Positives = 211/273 (77%), Gaps = 7/273 (2%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVHLGLLLGVGGHMQELRRVRSG L END++VTMHDV+DAQW+YDN +DESYLRRVI
Sbjct: 202 RTLCVHLGLLLGVGGHMQELRRVRSGCLSENDDIVTMHDVLDAQWIYDNTRDESYLRRVI 261
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE +L YKR+VVKDSAVNAICYGAKLMIPGLLR+E ++V E+VL+TTKGEAIAVG
Sbjct: 262 RPLESLLVGYKRIVVKDSAVNAICYGAKLMIPGLLRYEAGIEVNEEIVLITTKGEAIAVG 321
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA+M+T ++TCDHGVVAK+KR +M+RD YPR+WGLGP++ KK L +GKLDK+G+PNE
Sbjct: 322 IAQMSTVELSTCDHGVVAKVKRCIMERDVYPRRWGLGPQSMKKKTLKKEGKLDKYGRPNE 381
Query: 761 KTPVEWSRNVVLPTGGDAMVAG----AAAAPEKVEAESGEV---RKRKLDESSDSPAPVS 603
TP +WS++ + + +A VA A A VEAE V +KRK ESS+ +
Sbjct: 382 NTPADWSKSYIDYSDPNAEVAKPAPVVAPAAPTVEAEVNGVEDSKKRKSVESSEKDEDEA 441
Query: 602 TKKAKTKEVEVEEKVKSEKKEKKKKKDKEEDKE 504
KK + + + +K K EKKEKK+KK+K++ E
Sbjct: 442 AKKEEKRRKKEAKKEKKEKKEKKEKKEKKKKSE 474
>sp|P40615|DKC1_RAT H/ACA ribonucleoprotein complex subunit 4 OS=Rattus
norvegicus GN=Dkc1 PE=1 SV=4
Length = 509
Score = 333 bits (852), Expect = 2e-090
Identities = 166/281 (59%), Positives = 211/281 (75%), Gaps = 10/281 (3%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVHLGLLLGVGG MQELRRVRSG++GE D+MVTMHDV+DAQ++YD+++DESYLRRV+
Sbjct: 228 RTLCVHLGLLLGVGGQMQELRRVRSGVVGERDHMVTMHDVLDAQYLYDHHRDESYLRRVV 287
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE +LTS+KRLV+KDSAVNAICYGAK+M+PGLLR+E+ ++V EVV++TTKGEA+ V
Sbjct: 288 FPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGLLRYEDGIEVNQEVVVITTKGEAVCVA 347
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA MTT+V++TCDHGVVAKIKRV+M+RDTYPRKWGLGP+AS KK+LI G LDKHG+P +
Sbjct: 348 IALMTTAVISTCDHGVVAKIKRVIMERDTYPRKWGLGPKASQKKQLIKQGLLDKHGRPTD 407
Query: 761 KTPVEWSRNVVLPTGGDAMVAGAAAAP-EKVEAESGEVRKRKLDESSDSPAPVSTKKAKT 585
TP W+R+ V + A A P V A++ + KRK D SD+ T
Sbjct: 408 GTPASWTRDYVDYSDSSKKATAAEATPGPGVTADAASIVKRKRDSDSDADEATPT----- 462
Query: 584 KEVEVEEKVKSEKKEKKKKKDKEEDKEELATPKSEKKKKKK 462
+VK EKK+KK+K D E+ E + +KKKKK
Sbjct: 463 ----TTPRVKKEKKKKKEKADGGEEAAEDGDGDATRKKKKK 499
>sp|P33322|CBF5_YEAST H/ACA ribonucleoprotein complex subunit 4 OS=Saccharomyces
cerevisiae GN=CBF5 PE=1 SV=1
Length = 483
Score = 331 bits (847), Expect = 9e-090
Identities = 164/287 (57%), Positives = 210/287 (73%), Gaps = 4/287 (1%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVHLG+LLGVGGHMQELRRVRSG L ENDNMVT+HDVMDAQW+YDN +DESYLR +I
Sbjct: 197 RTLCVHLGMLLGVGGHMQELRRVRSGALSENDNMVTLHDVMDAQWVYDNTRDESYLRSII 256
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE +L YKR+VVKDSAVNA+CYGAKLMIPGLLR+E +++ E+VL+TTKGEAIAV
Sbjct: 257 QPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIELYDEIVLITTKGEAIAVA 316
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA+M+T +A+CDHGVVA +KR +M+RD YPR+WGLGP A KK++ ADGKLDK+G+ NE
Sbjct: 317 IAQMSTVDLASCDHGVVASVKRCIMERDLYPRRWGLGPVAQKKKQMKADGKLDKYGRVNE 376
Query: 761 KTPVEWSRNVVLPTGGDAMVAGAAAAPEKVE----AESGEVRKRKLDESSDSPAPVSTKK 594
TP +W + V + + + E E A+ + K E + S K+
Sbjct: 377 NTPEQWKKEYVPLDNAEQSTSSSQETKETEEEPKKAKEDSLIKEVETEKEEVKEDDSKKE 436
Query: 593 AKTKEVEVEEKVKSEKKEKKKKKDKEEDKEELATPKSEKKKKKKSKE 453
K K+ + E+K K EKK+KK+KK+K+E K + SE+KK KKSK+
Sbjct: 437 KKEKKDKKEKKEKKEKKDKKEKKEKKEKKRKSEDGDSEEKKSKKSKK 483
>sp|O60832|DKC1_HUMAN H/ACA ribonucleoprotein complex subunit 4 OS=Homo sapiens
GN=DKC1 PE=1 SV=3
Length = 514
Score = 327 bits (838), Expect = 1e-088
Identities = 164/288 (56%), Positives = 213/288 (73%), Gaps = 7/288 (2%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVHLGLLLGVGG MQELRRVRSG++ E D+MVTMHDV+DAQW+YDN+KDESYLRRV+
Sbjct: 227 RTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVV 286
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE +LTS+KRLV+KDSAVNAICYGAK+M+PG+LR+E+ ++V E+V++TTKGEAI +
Sbjct: 287 YPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMA 346
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA MTT+V++TCDHG+VAKIKRV+M+RDTYPRKWGLGP+AS KK +I G LDKHGKP +
Sbjct: 347 IALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTD 406
Query: 761 KTPVEWSRNVV--LPTGGDAMVAGAAAAPEKV-EAESGEVRKRKLDESSDSPAPVSTKKA 591
TP W + V + +VA AP+ V EA RKR+ + SD P + +
Sbjct: 407 STPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLI 466
Query: 590 KTKEVEVEEKVKSEKKEKKKKKDKEEDKEELATPKSEKKKKKKSKETD 447
K + ++K K +KK K + E + + +KKKKKK+KE +
Sbjct: 467 KKE----KKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 510
>sp|O43101|CBF5_CANAL Centromere/microtubule-binding protein CBF5 OS=Candida
albicans GN=CBF5 PE=3 SV=1
Length = 479
Score = 323 bits (826), Expect = 3e-087
Identities = 161/283 (56%), Positives = 211/283 (74%), Gaps = 4/283 (1%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVHLG+LLGVGGHMQELRRVRSG + E+DN+VT+HDV+DAQ++YDN +DESYLR++I
Sbjct: 198 RTLCVHLGMLLGVGGHMQELRRVRSGAMSESDNLVTLHDVLDAQYVYDNTRDESYLRKII 257
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE +L YKR+VVKDSAVN++CYGAKLMIPGLLR+E +++ EVVLMTTKGEAIA+G
Sbjct: 258 QPLESLLVGYKRVVVKDSAVNSVCYGAKLMIPGLLRYEEGIELYDEVVLMTTKGEAIAIG 317
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA+M+T + +CDHG+VAK+KR +M+RDTYPR+WGLGP A KK++ ADGKLDK+G+ NE
Sbjct: 318 IAQMSTVDLQSCDHGIVAKVKRCIMERDTYPRRWGLGPIAQKKKQMKADGKLDKYGRVNE 377
Query: 761 KTPVEWSRNVVLPTGGDAMVAGAAAAPEKVEAESGEVRKRKLDESSDSPAPVSTK-KAKT 585
TP W ++ D A + V E +K+ L E + V K + K
Sbjct: 378 NTPENWKKDY---KDLDEQPAPPIPESKLVAPEPQLPKKKSLIEEVEVDIDVEDKSEKKE 434
Query: 584 KEVEVEEKVKSEKKEKKKKKDKEEDKEELATPKSEKKKKKKSK 456
K+ + E+K K +KKEKK+KKDK+E K + S+ +KKKKSK
Sbjct: 435 KKDKKEKKEKKDKKEKKEKKDKKEKKRKAEDDSSKSEKKKKSK 477
>sp|O43100|CBF5_EMENI Centromere/microtubule-binding protein CBF5 OS=Emericella
nidulans GN=cbf5 PE=2 SV=1
Length = 481
Score = 320 bits (818), Expect = 2e-086
Identities = 157/275 (57%), Positives = 206/275 (74%), Gaps = 8/275 (2%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVHLGLLLGVG HMQELRRVRSG + EN+ MVT+HDV+DAQW+YDN +DESYLR+VI
Sbjct: 199 RTLCVHLGLLLGVGAHMQELRRVRSGAMSENEGMVTLHDVLDAQWLYDNQRDESYLRKVI 258
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE +LT+YKR+VVKDSAVNA+CYGAKLMIPGLLRFE +++G EVVLMTTKGEAIA+G
Sbjct: 259 KPLESLLTTYKRIVVKDSAVNAVCYGAKLMIPGLLRFEAGIELGEEVVLMTTKGEAIAIG 318
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA+M+T ++TCDHGVVAK+KR +M+RD YPR+WGLGP A KKKL + GKLDK+G+ NE
Sbjct: 319 IAQMSTVELSTCDHGVVAKVKRCIMERDLYPRRWGLGPVALEKKKLKSSGKLDKYGRANE 378
Query: 761 KTPVEWS---RNVVLPTGGDA-----MVAGAAAAPEKVEAESGEVRKRKLDESSDSPAPV 606
TP +W ++ P G + +VA A+P++ + K +D++ D
Sbjct: 379 ATPAKWKSEYKDYSAPDGDSSQQAVDVVAKEEASPKEEPSLEANESKMDIDDAQDDEDKK 438
Query: 605 STKKAKTKEVEVEEKVKSEKKEKKKKKDKEEDKEE 501
K+ + + E + K +KKEKK+KK++ + K+E
Sbjct: 439 KRKRHEGETPEERAERKRKKKEKKEKKERRKSKQE 473
>sp|O43102|CBF5_ASPFU Centromere/microtubule-binding protein cbf5 OS=Aspergillus
fumigatus GN=cbf5 PE=2 SV=1
Length = 487
Score = 317 bits (811), Expect = 1e-085
Identities = 161/284 (56%), Positives = 204/284 (71%), Gaps = 4/284 (1%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVHLGLLLGVG HMQELRRVRSG + EN+ +VT+HDV+DAQWMYDN +DESYLRRVI
Sbjct: 204 RTLCVHLGLLLGVGAHMQELRRVRSGAMDENNGLVTLHDVLDAQWMYDNQRDESYLRRVI 263
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE +LT+YKR+VVKDSAVNA+CYGAKLMIPGLLRFE ++V EVVLMTTKGEAIA+G
Sbjct: 264 QPLESLLTTYKRIVVKDSAVNAVCYGAKLMIPGLLRFEAGIEVNEEVVLMTTKGEAIAIG 323
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA+M+T ++TCDHGVVAK+KR +M+RD YPR+WGLGP A KKKL + GKLDK+G+ NE
Sbjct: 324 IAQMSTVELSTCDHGVVAKVKRCIMERDLYPRRWGLGPVALEKKKLKSAGKLDKYGRANE 383
Query: 761 KTPVEWS---RNVVLPTGGDAMVAGAAAAPEKVEAESGEVRKRKLDESSDSPAPVSTKKA 591
TP +W ++ P A A + A E V A + + + S S V K
Sbjct: 384 DTPAKWKTEYKDYSAPEEASAHAASESTAKEDV-AAALTTEQDEAPSSPQSKMDVDETKE 442
Query: 590 KTKEVEVEEKVKSEKKEKKKKKDKEEDKEELATPKSEKKKKKKS 459
+ K E + E+ E+K+KK ++++K+E K EK+ S
Sbjct: 443 EKKRKRHEGETAEERAERKRKKKEKKEKKERRKSKQEKEDSDDS 486
>sp|Q9ESX5|DKC1_MOUSE H/ACA ribonucleoprotein complex subunit 4 OS=Mus musculus
GN=Dkc1 PE=1 SV=3
Length = 509
Score = 317 bits (810), Expect = 2e-085
Identities = 159/285 (55%), Positives = 211/285 (74%), Gaps = 8/285 (2%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVHL +LG G MQELRRVRSG++ E D+MVTMHDV+DAQW+YDN+KDESYLRRV+
Sbjct: 227 RTLCVHLCFVLGSGCQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVV 286
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE +LTS+KRLV+KDSAVNAICYGAK+M+PGLLR+E+ ++V E+V++TTKGEAI +
Sbjct: 287 YPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGLLRYEDGIEVNQEIVVITTKGEAICMA 346
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA MTT+V++TCDHG+VAKIKRV+M+RDTYPRKWGLGP+AS KK +I G LDKHGKP +
Sbjct: 347 IALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKMMIKQGLLDKHGKPTD 406
Query: 761 KTPVEWSRNVV--LPTGGDAMVAGAAAAPEKVEAESGEVRKRKLDESSDSPAPVSTKKAK 588
TP W ++ + +G + +V A AP+ + AE+ V KRK D S+S + + K
Sbjct: 407 NTPATWKQDYIDYSDSGKNTLVTEAVQAPQ-LAAEAVNVIKRKRDSESESDETPTVPQLK 465
Query: 587 TKEVEVEEKVKSEKKEKKKKKDKEEDKEELATPKSEKKKKKKSKE 453
K+ + ++K K+ + + D + D T K +KKKK K E
Sbjct: 466 EKKKKKDKKPKTVLESGGETGDGDND-----TTKKKKKKKVKVVE 505
>sp|O44081|DKC1_DROME H/ACA ribonucleoprotein complex subunit 4 OS=Drosophila
melanogaster GN=Nop60B PE=1 SV=1
Length = 508
Score = 309 bits (791), Expect = 3e-083
Identities = 155/283 (54%), Positives = 199/283 (70%), Gaps = 5/283 (1%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RTMCVHLGL+LGVGG M ELRRVRSGI E D MVTMHDV+DA W+Y+N+KDES LRRVI
Sbjct: 225 RTMCVHLGLVLGVGGQMLELRRVRSGIQSERDGMVTMHDVLDAMWLYENHKDESMLRRVI 284
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE +L ++KR+++KDS+VNA+CYGAK+ +PG+LR+E+ +++ E+V+ TTKGEAI +
Sbjct: 285 KPLEGLLVNHKRIIMKDSSVNAVCYGAKITLPGVLRYEDGIEIDQEIVICTTKGEAICLA 344
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA MTT+ MA+CDHGVVAKIKRV+M+RDTYPRKWGLGP+AS KK LIA GKLDK G+PNE
Sbjct: 345 IALMTTATMASCDHGVVAKIKRVIMERDTYPRKWGLGPKASAKKALIAAGKLDKFGRPNE 404
Query: 761 KTPVEWSRNVVLPTGGDAMVAGAAAAPEKVEAESGEVRKRKLDESSDSPAPVSTKKAKTK 582
TP EW V D AA S E KRKL SS + +T
Sbjct: 405 NTPKEWLTGYV-----DYNAKKPAAQEVSPTNGSSEPSKRKLSTSSVEETAAAAVSEETP 459
Query: 581 EVEVEEKVKSEKKEKKKKKDKEEDKEELATPKSEKKKKKKSKE 453
+ ++K K K +++ + EE+ E + K +KKKK K ++
Sbjct: 460 SKDKKKKKKKHKGDEEAPEAAEEEAEPVEKEKKKKKKKDKDRD 502
>sp|O17919|DKC1_CAEEL Putative H/ACA ribonucleoprotein complex subunit 4
OS=Caenorhabditis elegans GN=K01G5.5 PE=2 SV=1
Length = 445
Score = 282 bits (720), Expect = 5e-075
Identities = 133/228 (58%), Positives = 174/228 (76%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVHLGL+LG GG MQELRR RSGI EN+NMVTMHDV+DAQ++ D KDESY+R ++
Sbjct: 215 RTICVHLGLILGCGGQMQELRRNRSGICDENENMVTMHDVLDAQYLLDTQKDESYMRHIV 274
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE +LT +KR+VVKDS +NAICYGAK++IPG+LR+++D++VG E+V+M+TKGEAI +
Sbjct: 275 RPLEALLTQHKRVVVKDSCINAICYGAKILIPGILRYDDDIEVGKEIVIMSTKGEAICIA 334
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA+M TS +A+ DHGVVAK KRV+M+RD Y RKWGLGP AS KK+++ DG LDK GKPN+
Sbjct: 335 IAQMNTSTIASVDHGVVAKSKRVIMERDVYGRKWGLGPVASKKKQMVKDGLLDKFGKPND 394
Query: 761 KTPVEWSRNVVLPTGGDAMVAGAAAAPEKVEAESGEVRKRKLDESSDS 618
TP W++ V + + E+ EA + +K K ESSDS
Sbjct: 395 TTPKSWAKEYVQTSTKKEVKKEETPDEEEEEAPKKKSKKSKKQESSDS 442
>sp|Q60YA8|DKC1_CAEBR Putative H/ACA ribonucleoprotein complex subunit 4
OS=Caenorhabditis briggsae GN=CBG18316 PE=3 SV=1
Length = 445
Score = 275 bits (702), Expect = 6e-073
Identities = 135/233 (57%), Positives = 176/233 (75%), Gaps = 8/233 (3%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
RT+CVHLGL+LG GG MQELRR RSGI EN+NMVTMHDV+DAQ+M D KDESY+R ++
Sbjct: 215 RTICVHLGLILGCGGQMQELRRNRSGICDENENMVTMHDVLDAQYMLDTQKDESYMRHIV 274
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
PLE +LT +KR+VVKDS VNAICYGAK++IPG+LR+++D++VG E+V+MTTKGEAI +
Sbjct: 275 RPLEALLTQHKRVVVKDSCVNAICYGAKILIPGILRYDDDIEVGKEIVIMTTKGEAICIA 334
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHGKPNE 762
IA+M+TS +A+ DHG+VAK KRV+M+RD Y RKWGLGP AS KK+++ DG LDK GKPN
Sbjct: 335 IAQMSTSTIASVDHGIVAKSKRVIMERDVYGRKWGLGPVASKKKQMVKDGLLDKFGKPNI 394
Query: 761 KTPVEWSR-----NVVLPTGGDAMVAGAAAAPEKVEAESGEVRKRKLDESSDS 618
TP W++ + V D AP+K +S + K+++ SSDS
Sbjct: 395 TTPKSWAKEYVQTDKVKKEQEDKEDEEEEEAPKK---KSKKAAKKEVSSSSDS 444
>sp|Q980C3|TRUB_SULSO Probable tRNA pseudouridine synthase B OS=Sulfolobus
solfataricus GN=truB PE=3 SV=1
Length = 251
Score = 139 bits (349), Expect = 5e-032
Identities = 65/154 (42%), Positives = 101/154 (65%), Gaps = 1/154 (0%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
R +C +G++ G G HM+ELRR RSGI E+ N+V +H++ +A ++Y N KDE+ LRRV+
Sbjct: 94 RKLCHDIGIIYGCGAHMRELRRTRSGIFTESTNLVKLHELSEAIYLYKNCKDETELRRVL 153
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
+P+E ++V++DSAVNA+ YGA+L +PG++ ++N T V ++T KGE +A G
Sbjct: 154 IPMEFATCEIPKIVIEDSAVNALAYGAQLAVPGVVAYQNFKKNDT-VAVLTLKGELVATG 212
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKW 840
A M + + G+V + RV M RD YP+ W
Sbjct: 213 NALMDSEELENAKKGIVVNLSRVFMQRDIYPKAW 246
>sp|Q8TZ08|TRUB_METKA Probable tRNA pseudouridine synthase B OS=Methanopyrus
kandleri GN=truB PE=3 SV=1
Length = 338
Score = 136 bits (342), Expect = 3e-031
Identities = 71/159 (44%), Positives = 101/159 (63%), Gaps = 7/159 (4%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESY---LR 1131
R +C +G LGVG HM ELRR R+G E +N VT+HDV DA Y+ +K+E + LR
Sbjct: 179 RKLCHDIGEALGVGAHMAELRRTRTGPFSE-ENAVTLHDVKDA---YEFWKEEGWEEPLR 234
Query: 1130 RVIMPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAI 951
V+ P+E L R+ ++D+AV+AIC+GA L PG++R E + G V + T KGEA+
Sbjct: 235 HVVRPMEEGLEHLPRIEIRDTAVDAICHGANLAAPGIVRVEKGIQPGDLVAIFTLKGEAV 294
Query: 950 AVGIAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGL 834
A+G+A+ T M D G++ KRV+M+ TYP+ WGL
Sbjct: 295 ALGVAKATWKEMLHADRGIMVDTKRVLMEPGTYPKAWGL 333
>sp|Q57612|TRUB_METJA Probable tRNA pseudouridine synthase B
OS=Methanocaldococcus jannaschii GN=truB PE=1 SV=1
Length = 336
Score = 132 bits (332), Expect = 5e-030
Identities = 70/154 (45%), Positives = 93/154 (60%), Gaps = 1/154 (0%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
R +C +G LG HMQELRR +SG E D V + D++DA + DE LRRVI
Sbjct: 180 RKLCEDIGEALGTSAHMQELRRTKSGCFEEKD-AVYLQDLLDAYVFWKEDGDEEELRRVI 238
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
P+E L K++VVKDSAV+AIC+GA + + G+ + + G V++ T KGEA+AVG
Sbjct: 239 KPMEYGLRHLKKVVVKDSAVDAICHGADVYVRGIAKLSKGIGKGETVLVETLKGEAVAVG 298
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKW 840
A M T + D GV ++RV MDR TYPR W
Sbjct: 299 KALMNTKEILNADKGVAVDVERVYMDRGTYPRMW 332
>sp|B1L793|TRUB_KORCO Probable tRNA pseudouridine synthase B OS=Korarchaeum
cryptofilum (strain OPF8) GN=truB PE=3 SV=1
Length = 325
Score = 126 bits (316), Expect = 4e-028
Identities = 69/157 (43%), Positives = 94/157 (59%), Gaps = 1/157 (0%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
R + +G LGVGG M++LRR+RSGI E D VT+ D+ DA + DES +R+VI
Sbjct: 170 RKLFFDIGEFLGVGGSMRDLRRIRSGIFTEKD-CVTLEDIKDAYDSWRESGDESKIRKVI 228
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
+PLE + ++ VKDSAV ++ +GA L + G+ + G+ V LMT KGE IA+G
Sbjct: 229 LPLEEAVRHLPKIYVKDSAVASLTHGASLKVKGICSLSRGIKKGSIVALMTLKGELIAIG 288
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLG 831
A M M + D GV A I+RV+M RD YP W G
Sbjct: 289 RALMDFDEMLSADSGVAASIERVIMPRDLYPPMWKTG 325
>sp|Q7LWY0|TRUB_PYRFU Probable tRNA pseudouridine synthase B OS=Pyrococcus
furiosus GN=truB PE=1 SV=1
Length = 340
Score = 124 bits (309), Expect = 2e-027
Identities = 59/154 (38%), Positives = 92/154 (59%)
Frame = -2
Query: 1301 RTMCVHLGLLLGVGGHMQELRRVRSGILGENDNMVTMHDVMDAQWMYDNYKDESYLRRVI 1122
R++ H+GL LGVG HM ELRR RSG E++ ++T+HD++D + + E Y R+ I
Sbjct: 181 RSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAI 240
Query: 1121 MPLEVILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDVDVGTEVVLMTTKGEAIAVG 942
P+E + ++ +KDSAV A+ +GA L +PG+ + + G V +MT K E +A+G
Sbjct: 241 QPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALG 300
Query: 941 IAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKW 840
A MT+ M G+ +++V M RD YP+ W
Sbjct: 301 KAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLW 334
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,771,599,260
Number of Sequences: 518415
Number of Extensions: 58771599260
Number of Successful Extensions: 389091298
Number of sequences better than 0.0: 0
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