BLASTX 7.6.2
Query= UN14642 /QuerySize=1761
(1760 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q05047|C72A1_CATRO Secologanin synthase OS=Catharanthus roseu... 329 7e-089
sp|P15129|CP4B1_RAT Cytochrome P450 4B1 OS=Rattus norvegicus GN=... 117 4e-025
sp|O08336|CYPE_BACSU Probable bifunctional P-450/NADPH-P450 redu... 114 3e-024
sp|O17624|C13B1_CAEEL Putative cytochrome P450 cyp-13B1 OS=Caeno... 113 6e-024
sp|Q27517|C13A3_CAEEL Putative cytochrome P450 CYP13A3 OS=Caenor... 112 1e-023
sp|Q27520|C13A1_CAEEL Putative cytochrome P450 CYP13A1 OS=Caenor... 109 1e-022
sp|Q27518|C13A2_CAEEL Putative cytochrome P450 CYP13A2 OS=Caenor... 109 1e-022
sp|Q27515|C13A6_CAEEL Putative cytochrome P450 CYP13A6 OS=Caenor... 108 2e-022
sp|Q9VYT8|C28C1_DROME Probable cytochrome P450 28c1 OS=Drosophil... 107 4e-022
sp|P58045|C71AE_ARATH Cytochrome P450 71A14 OS=Arabidopsis thali... 103 5e-021
sp|Q9VYQ7|CP311_DROME Probable cytochrome P450 311a1 OS=Drosophi... 103 5e-021
sp|Q59990|CP120_SYNY3 Putative cytochrome P450 120 OS=Synechocys... 99 7e-020
sp|Q9FH66|C71AG_ARATH Cytochrome P450 71A16 OS=Arabidopsis thali... 85 2e-015
sp|Q9T0K0|C71AJ_ARATH Cytochrome P450 71A19 OS=Arabidopsis thali... 81 2e-014
sp|Q9HCS2|CP4FC_HUMAN Cytochrome P450 4F12 OS=Homo sapiens GN=CY... 77 3e-013
sp|P51870|CP4F5_RAT Cytochrome P450 4F5 OS=Rattus norvegicus GN=... 72 1e-011
sp|Q9HBI6|CP4FB_HUMAN Cytochrome P450 4F11 OS=Homo sapiens GN=CY... 69 7e-011
sp|Q9EP75|CP4FE_MOUSE Leukotriene-B4 omega-hydroxylase 3 OS=Mus ... 69 1e-010
sp|P33274|CP4F1_RAT Cytochrome P450 4F1 OS=Rattus norvegicus GN=... 66 6e-010
>sp|Q05047|C72A1_CATRO Secologanin synthase OS=Catharanthus roseus GN=CYP72A1
PE=2 SV=1
Length = 524
Score = 329 bits (841), Expect = 7e-089
Identities = 150/268 (55%), Positives = 204/268 (76%), Gaps = 6/268 (2%)
Frame = +1
Query: 778 PNKGQ*KIKAAAKETHDILKGLVNKRLRAREAGEASNEDLLGILLESNL------GQAKG 939
P K ++K KE D+L+ ++NKR++A +AGE +DLLG+LLESN+ G K
Sbjct: 255 PTKRNKRMKEINKEITDMLRFIINKRMKALKAGEPGEDDLLGVLLESNIQEIQKQGNKKD 314
Query: 940 NGMSVDDVIEECKLFYFAGQETTSVLLVWTMILLSQHQDWQARAREEVKQVFGDKEPDTE 1119
GMS++DVIEECKLFYFAGQETT VLL WT ILLS+H +WQ RAREEV Q FG +P+ E
Sbjct: 315 GGMSINDVIEECKLFYFAGQETTGVLLTWTTILLSKHPEWQERAREEVLQAFGKNKPEFE 374
Query: 1120 GLNHLKTMTMIINEVLRLYPPVTQLSRTIHKEMKLGDLTLPGGVHISLPIMLVQRDTQLW 1299
LNHLK ++MI+ EVLRLYPPV L++ +HK+ KLG T+P G + LP +++ R+ +W
Sbjct: 375 RLNHLKYVSMILYEVLRLYPPVIDLTKIVHKDTKLGSYTIPAGTQVMLPTVMLHREKSIW 434
Query: 1300 GNNAAEFNPERFKDGVSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRFSFE 1479
G +A EFNP RF DGV+ ATK+ V++ PF+WGPR+C+GQNFALL+AK+ +A+ILQRF F+
Sbjct: 435 GEDAMEFNPMRFVDGVANATKNNVTYLPFSWGPRVCLGQNFALLQAKLGLAMILQRFKFD 494
Query: 1480 LSPSYVHAPYTVFTLHPEYGAHLILHKL 1563
++PSYVHAP+T+ T+ P++G+H+I KL
Sbjct: 495 VAPSYVHAPFTILTVQPQFGSHVIYKKL 522
Score = 245 bits (623), Expect = 1e-063
Identities = 120/271 (44%), Positives = 174/271 (64%), Gaps = 4/271 (1%)
Frame = +2
Query: 17 LETKMQTSAASAIVSGAIAVVLWWIWKTLKWVWFEPKMLESYLRRQGIAGTPYTPLVGDM 196
+E M T AI + A+V+ W W+ L W WF PK +E LR+QG G PY LVGD+
Sbjct: 1 MEMDMDT-IRKAIAATIFALVMAWAWRVLDWAWFTPKRIEKRLRQQGFRGNPYRFLVGDV 59
Query: 197 RTNNRMTNEARSKPIKLTDDIIPRVLPFSSHMLKTYGRTFFTWRGTIPTITITDPEQIKE 376
+ + +M EA SKP++ +DI+PR++P +H + TYGR FTW G IP I + +PE IKE
Sbjct: 60 KESGKMHQEALSKPMEFNNDIVPRLMPHINHTINTYGRNSFTWMGRIPRIHVMEPELIKE 119
Query: 377 VFNKVYDFPKPHTF--PLSNLIVSGLFSYDGDKWSKHRRIINPAFHLQKIKNMVPVFHQS 550
V + K PL +++G+ S++G KWSKHRRII+PAF L+K+K+M+P F
Sbjct: 120 VLTHSSKYQKNFDVHNPLVKFLLTGVGSFEGAKWSKHRRIISPAFTLEKLKSMLPAFAIC 179
Query: 551 CNEVIDKWDRIVSDKGSSCEVDVWPGLMSITEDVISRTAFGSSYKDGQRIFELQTELAQL 730
++++ KW++I +GS EVD++P +T DVIS+ AFGS+Y++G +IF L EL L
Sbjct: 180 YHDMLTKWEKIAEKQGSH-EVDIFPTFDVLTSDVISKVAFGSTYEEGGKIFRLLKELMDL 238
Query: 731 IIQAFSKSYIPGYRYLPTKDNRRLKQQPKKL 823
I YIPG+ YLPTK N+R+K+ K++
Sbjct: 239 TIDCMRDVYIPGWSYLPTKRNKRMKEINKEI 269
>sp|P15129|CP4B1_RAT Cytochrome P450 4B1 OS=Rattus norvegicus GN=Cyp4b1 PE=1
SV=3
Length = 511
Score = 117 bits (291), Expect = 4e-025
Identities = 84/261 (32%), Positives = 130/261 (49%), Gaps = 13/261 (4%)
Frame = +1
Query: 808 AAKETHDILKGLVNKRLRA-------REAGEASNEDLLGILLESNLGQAKGNGMSVDDVI 966
A K HD ++ +R A ++ + + D L ILL + G +S ++
Sbjct: 249 ACKIAHDHTDEVIRQRKAALQDEKERKKIQQRRHLDFLDILL--GVRDESGIKLSDAELR 306
Query: 967 EECKLFYFAGQETTSVLLVWTMILLSQHQDWQARAREEVKQVFGDKEP-DTEGLNHLKTM 1143
E F F G +TT+ + W + ++ + + Q REEV+ + GD++ + L + +
Sbjct: 307 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQLCREEVRGILGDQDSFQWDDLAKMTYL 366
Query: 1144 TMIINEVLRLYPPVTQLSRTIHKEMKLGD-LTLPGGVHISLPIMLVQRDTQLWGNNAAEF 1320
TM + E RLYPPV Q+ R ++K + D +LP G ISL I + R++ +W + F
Sbjct: 367 TMCMKECFRLYPPVPQVYRQLNKPVTFVDGRSLPAGSLISLHIYALHRNSTVWPDPEV-F 425
Query: 1321 NPERFKDGVSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRFSFELSPSYVH 1500
+P RF + A + +F PF+ GPR CIGQ FA+ E K+ AL L RF F L PS +
Sbjct: 426 DPLRFSP-ENAAGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSLDPSKMP 484
Query: 1501 APYTVFTLHPEYGAHLILHKL 1563
L + G HL L L
Sbjct: 485 IKVPQLILRSKNGIHLYLKPL 505
>sp|O08336|CYPE_BACSU Probable bifunctional P-450/NADPH-P450 reductase 2
OS=Bacillus subtilis GN=cypE PE=2 SV=1
Length = 1054
Score = 114 bits (284), Expect = 3e-024
Identities = 74/248 (29%), Positives = 124/248 (50%), Gaps = 6/248 (2%)
Frame = +1
Query: 796 KIKAAAKETHDILKGLVNKRLRAREAGEASN-EDLLGILLESNLGQAKGNGMSVDDVIEE 972
K K ++ +++ LV++ + R+A N +DLL ++L + G + +++ +
Sbjct: 202 KTKLQFQKDIEVMNSLVDRMIAERKANPDENIKDLLSLMLYAK-DPVTGETLDDENIRYQ 260
Query: 973 CKLFYFAGQETTSVLLVWTMILLSQHQDWQARAREEVKQVFGDKEPDTEGLNHLKTMTMI 1152
F AG ETTS LL + + L H + +A+EE +V D P+ + + LK + M+
Sbjct: 261 IITFLIAGHETTSGLLSFAIYCLLTHPEKLKKAQEEADRVLTDDTPEYKQIQQLKYIRMV 320
Query: 1153 INEVLRLYPPVTQLSRTIHKEMKL-GDLTLPGGVHISLPIMLVQRDTQLWGNNAAEFNPE 1329
+NE LRLYP S ++ L G+ + G +++ I + RD WG +A +F PE
Sbjct: 321 LNETLRLYPTAPAFSLYAKEDTVLGGEYPISKGQPVTVLIPKLHRDQNAWGPDAEDFRPE 380
Query: 1330 RFKDGVSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRFSFELSPSYVHAPY 1509
RF+D ++ ++ PF G R CIG FAL EA M + L+L+ F Y
Sbjct: 381 RFED---PSSIPHHAYKPFGNGQRACIGMQFALQEATMVLGLVLKHFELINHTGYELKIK 437
Query: 1510 TVFTLHPE 1533
T+ P+
Sbjct: 438 EALTIKPD 445
>sp|O17624|C13B1_CAEEL Putative cytochrome P450 cyp-13B1 OS=Caenorhabditis
elegans GN=cyp-13B1 PE=2 SV=2
Length = 527
Score = 113 bits (281), Expect = 6e-024
Identities = 64/176 (36%), Positives = 98/176 (55%), Gaps = 4/176 (2%)
Frame = +1
Query: 946 MSVDDVIEECKLFYFAGQETTSVLLVWTMILLSQHQDWQARAREEVKQVFGDKEPDTEGL 1125
++ +DVI C +F AG +TT+ L + LL++H + A+EEV V G + + +
Sbjct: 305 VTAEDVIGACFVFLLAGFDTTANSLAYASYLLAKHPEKMKLAQEEVDTVVGSENVSYDDM 364
Query: 1126 NHLKTMTMIINEVLRLYPPV-TQLSRTIHKEMKLGDLTLPGGVHISLPIMLVQRDTQLWG 1302
LK + ++ E LRLYP SR K LGD+ + GV I +M + R ++WG
Sbjct: 365 TKLKYLDAVVRESLRLYPVAWFACSRECVKPTTLGDIYIDKGVKIEADVMSLHRSKEIWG 424
Query: 1303 NNAAEFNPERFKDGVSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRF 1470
NA +F PER+ + S+ T +S+ PF GPR C+G L EAK A+A +L+R+
Sbjct: 425 ENADDFVPERWLEPSSRHT---MSWIPFGAGPRQCVGMRLGLSEAKTALAHLLRRY 477
>sp|Q27517|C13A3_CAEEL Putative cytochrome P450 CYP13A3 OS=Caenorhabditis
elegans GN=cyp-13A3 PE=2 SV=1
Length = 520
Score = 112 bits (279), Expect = 1e-023
Identities = 63/183 (34%), Positives = 103/183 (56%), Gaps = 10/183 (5%)
Frame = +1
Query: 946 MSVDDVIEECKLFYFAGQETTSVLLVWTMILLSQHQDWQARAREEVKQVFGDKEPDTEGL 1125
++ D++I + +F AG +TT++ L ++ LL++H + Q + +EEV + D E + L
Sbjct: 311 LTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDRECPDPEVTFDQL 370
Query: 1126 NHLKTMTMIINEVLRLYPPVTQLSRTIHKEMKLGDLTLPG-----GVHISLPIMLVQRDT 1290
+ LK M +I E LRLYP L+ +H + T+ G G ++ + D
Sbjct: 371 SKLKYMECVIKETLRLYP----LASIVHNRKCMKSTTVLGMKIEEGTNVQADTWTLHYDP 426
Query: 1291 QLWGNNAAEFNPERFKDGVSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRF 1470
+ WG NA EF PER++ G +A ++ ++ PF GPRICIG A +E KM +A IL+++
Sbjct: 427 KFWGENANEFKPERWESGDEQAV-AKGAYLPFGLGPRICIGMRLAYMEEKMLLAQILKKY 485
Query: 1471 SFE 1479
S E
Sbjct: 486 SLE 488
>sp|Q27520|C13A1_CAEEL Putative cytochrome P450 CYP13A1 OS=Caenorhabditis
elegans GN=cyp-13A1 PE=2 SV=1
Length = 519
Score = 109 bits (270), Expect = 1e-022
Identities = 57/179 (31%), Positives = 98/179 (54%), Gaps = 1/179 (0%)
Frame = +1
Query: 946 MSVDDVIEECKLFYFAGQETTSVLLVWTMILLSQHQDWQARAREEVKQVFGDKEPDTEGL 1125
++ ++++ +C +F AG +TT++ L + LL+ H + Q + +EEV + + E + L
Sbjct: 311 LTTEEIVGQCTVFLIAGFDTTALSLSYATYLLATHPEIQKKLQEEVNRECPNPEVTIDQL 370
Query: 1126 NHLKTMTMIINEVLRLYP-PVTQLSRTIHKEMKLGDLTLPGGVHISLPIMLVQRDTQLWG 1302
+ LK M + E LRLYP SR + KLG++ + G I + + D +WG
Sbjct: 371 SKLKYMECVFKEALRLYPLGAFANSRRCMRNTKLGNMKVEVGTMIQVDTWTLHTDPNIWG 430
Query: 1303 NNAAEFNPERFKDGVSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRFSFE 1479
++A +F PER++ S + + PF GPR CIG A +E K+ + IL++F+FE
Sbjct: 431 DDAEDFKPERWQTPNSDQIYQKSGYIPFGLGPRQCIGMRLAYMEEKILLVHILRKFTFE 489
>sp|Q27518|C13A2_CAEEL Putative cytochrome P450 CYP13A2 OS=Caenorhabditis
elegans GN=cyp-13A2 PE=2 SV=1
Length = 515
Score = 109 bits (270), Expect = 1e-022
Identities = 58/179 (32%), Positives = 97/179 (54%), Gaps = 3/179 (1%)
Frame = +1
Query: 946 MSVDDVIEECKLFYFAGQETTSVLLVWTMILLSQHQDWQARAREEVKQVFGDKEPDTEGL 1125
+S D+V+ +C LF G +TT++ L + LL+ + Q + EE+ + FG E + E L
Sbjct: 308 LSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREFGTSEVEFEKL 367
Query: 1126 NHLKTMTMIINEVLRLYPPVT-QLSRTIHKEMKLGDLTLPGGVHISLPIMLVQRDTQLWG 1302
LK M +I E LRLYP + SR K + + + GV++ + + D +LWG
Sbjct: 368 GRLKYMDCVIKEALRLYPLASISNSRKCMKTTTVNGVKIEAGVYVQMDTWSLHYDPELWG 427
Query: 1303 NNAAEFNPERFKDGVSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRFSFE 1479
+ EF PER+ + + + ++ PF GPR CIG A++E K+ + +L+ ++FE
Sbjct: 428 EDVKEFKPERW--STDEPLEHKGAYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTFE 484
>sp|Q27515|C13A6_CAEEL Putative cytochrome P450 CYP13A6 OS=Caenorhabditis
elegans GN=cyp-13A6 PE=2 SV=1
Length = 518
Score = 108 bits (268), Expect = 2e-022
Identities = 56/178 (31%), Positives = 100/178 (56%), Gaps = 1/178 (0%)
Frame = +1
Query: 946 MSVDDVIEECKLFYFAGQETTSVLLVWTMILLSQHQDWQARAREEVKQVFGDKEPDTEGL 1125
++ D++I +C +F AG +TT++ L + LL+ H + Q + +EEV + D E + L
Sbjct: 309 LTFDEIIAQCFVFLAAGFDTTALSLSYATYLLATHPEIQTKLQEEVDRECPDPEIFFDHL 368
Query: 1126 NHLKTMTMIINEVLRLYP-PVTQLSRTIHKEMKLGDLTLPGGVHISLPIMLVQRDTQLWG 1302
+ LK + ++ E LRLYP T +R +E + + G++I + + + ++WG
Sbjct: 369 SKLKYLECVMKETLRLYPLGTTANTRKCMRETTINGVNFDEGMNIQVDTWTLHHNPRIWG 428
Query: 1303 NNAAEFNPERFKDGVSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRFSF 1476
+ +F PER+++G + + S+ PF GPR CIG A +E K+ +A IL+ +SF
Sbjct: 429 EDVEDFKPERWENGACEHLEHNGSYIPFGSGPRQCIGMRLAQMEQKILLAQILKEYSF 486
>sp|Q9VYT8|C28C1_DROME Probable cytochrome P450 28c1 OS=Drosophila melanogaster
GN=Cyp28c1 PE=2 SV=1
Length = 505
Score = 107 bits (265), Expect = 4e-022
Identities = 78/231 (33%), Positives = 111/231 (48%), Gaps = 13/231 (5%)
Frame = +1
Query: 820 THDILKG-LVNKRLRAREAGEASNEDLLGILLESNLGQAKGNGMSVDDVIEECKLFYFAG 996
+HD G ++++ LR R + D + LLE + +S +D+ F F G
Sbjct: 246 SHDRFYGQMISEALRLRRSKHQERNDFINHLLE----MQRELDLSEEDMASHAMTFMFDG 301
Query: 997 QETTSVLLVWTMILLSQHQDWQARAREEVKQVF-GDKEPDTEGLNHLKTMTMIINEVLRL 1173
+TTS + ++LL ++ D Q R EE++ V G PD + L L ++ NE LR+
Sbjct: 302 LDTTSNSIAHCLLLLGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFNESLRI 361
Query: 1174 YPPVTQLSRTIHKEMKL------GDLTLPGGVHISLPIMLVQRDTQLWGNNAAEFNPERF 1335
YP S+T KE +L L L G H+ +PI + D L+ F PERF
Sbjct: 362 YPAGGWASKTCTKEYELRGSHHSEPLKLRPGDHVMVPIYALHNDPDLYPEPDV-FRPERF 420
Query: 1336 KDGVSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRFSFELSP 1488
DG K K Q F F GPR C+G L AK A+A I+QRF +SP
Sbjct: 421 LDGGLKNCKQQGIFLGFGNGPRQCVGMRLGLAMAKAALAAIVQRFEVVVSP 471
>sp|P58045|C71AE_ARATH Cytochrome P450 71A14 OS=Arabidopsis thaliana GN=CYP71A14
PE=2 SV=1
Length = 497
Score = 103 bits (256), Expect = 5e-021
Identities = 66/235 (28%), Positives = 115/235 (48%), Gaps = 12/235 (5%)
Frame = +1
Query: 796 KIKAAAKETHDILKGLVNKRLRAREAGEASNEDLLGILLESNLGQAKGNGMSVDDVIEEC 975
K + +K D+++ ++ + L +A + D + +LL + G + D+
Sbjct: 237 KAEEVSKAFGDLMEKVLQEHL---DATDKPTLDFVDVLLSLERHERNGVQIRRSDIKFLI 293
Query: 976 KLFYFAGQETTSVLLVWTMILLSQHQDWQARAREEV-----KQVFGDKEPDTEGLNHLKT 1140
+ AG ETT LL W M L +H + + ++E+ K + E D E + +LK
Sbjct: 294 LDMFLAGTETTYALLEWIMTELIRHPECMKKLQDEIRAKATKLILYISEEDVEDMKYLKA 353
Query: 1141 MTMIINEVLRLYPPVTQL-SRTIHKEMKLGDLTLPGGVHISLPIMLVQRDTQLWGNNAAE 1317
++ EVLRL+PP+ L R + +++KL + G + + +QRDT WG +A E
Sbjct: 354 ---VVKEVLRLHPPLPLLVPRELSEDIKLKGYDIAAGTQVIINAWAIQRDTMTWGIDAEE 410
Query: 1318 FNPERFKDGVSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRFSFEL 1482
F PER D + + F PF G RIC G FA+ ++ +A ++ RF++ +
Sbjct: 411 FRPERHLDSLVDFRGTNFEFIPFGSGRRICPGIGFAMALVEVTLANLVNRFNWRM 465
>sp|Q9VYQ7|CP311_DROME Probable cytochrome P450 311a1 OS=Drosophila melanogaster
GN=Cyp311a1 PE=2 SV=1
Length = 483
Score = 103 bits (256), Expect = 5e-021
Identities = 68/227 (29%), Positives = 115/227 (50%), Gaps = 11/227 (4%)
Frame = +1
Query: 823 HDILKGLVNKRLR-----AREAGEASNEDLLGILLESNLGQAKGNGMSVDDVIEECKLFY 987
H ++ ++ KR + AG A N LL LL L + +G +S ++ +E F
Sbjct: 237 HSQMESVIEKRAKELLDMGEPAGRAHN--LLDTLL---LAKFEGQSLSRREIRDEINTFV 291
Query: 988 FAGQETTSVLLVWTMILLSQHQDWQARAREEVKQVFGDKEPDTEGLNHLKTMTMIINEVL 1167
FAG +TT+ + + + L++ + Q R R+E++ V D+ D + LN L + +I EVL
Sbjct: 292 FAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDETTDLDALNGLPYLEALIKEVL 351
Query: 1168 RLYPPVTQLSRTIHKEMKLGDLTLPGGVHISLPIMLVQRDTQLWGNNAAEFNPERFKDGV 1347
RLY V R + ++G T GV + + + + D + + + A F PER+
Sbjct: 352 RLYTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYA-FKPERWLPED 410
Query: 1348 SKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRFSFELSP 1488
S+ PF+ GP +CIG+ ++LL K+ A +++ F ELSP
Sbjct: 411 GAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSP 457
>sp|Q59990|CP120_SYNY3 Putative cytochrome P450 120 OS=Synechocystis sp. (strain
PCC 6803) GN=cyp120 PE=1 SV=1
Length = 444
Score = 99 bits (246), Expect = 7e-020
Identities = 67/220 (30%), Positives = 107/220 (48%), Gaps = 3/220 (1%)
Frame = +1
Query: 829 ILKGLVNKRLRAREAGEASNEDLLGILLESNLGQAKGNGMSVDDVIEECKLFYFAGQETT 1008
+L + K ++AR+ S ED LGILL + +S+ ++ ++ L FAG ET
Sbjct: 202 LLLAELEKIIKARQQQPPSEEDALGILLAAR--DDNNQPLSLPELKDQILLLLFAGHETL 259
Query: 1009 SVLLVWTMILLSQHQDWQARAREEVKQVFGDKEPDTEGLNHLKTMTMIINEVLRLYPPVT 1188
+ L +LL QH D + R R+E ++ +E E L + + ++ EVLRL PPV
Sbjct: 260 TSALSSFCLLLGQHSDIRERVRQEQNKLQLSQELTAETLKKMPYLDQVLQEVLRLIPPVG 319
Query: 1189 QLSRTIHKEMKLGDLTLPGGVHISLPIMLVQRDTQLWGNNAAEFNPERFKDGVSKATKSQ 1368
R + ++ + P G +S I D L+ + +F+PERF S
Sbjct: 320 GGFRELIQDCQFQGFHFPKGWLVSYQISQTHADPDLY-PDPEKFDPERFTPDGSATHNPP 378
Query: 1369 VSFFPFAWGPRICIGQNFALLEAKMAMALILQRFSFELSP 1488
+ PF G R C+G+ FA LE K+ ++Q+F + L P
Sbjct: 379 FAHVPFGGGLRECLGKEFARLEMKLFATRLIQQFDWTLLP 418
>sp|Q9FH66|C71AG_ARATH Cytochrome P450 71A16 OS=Arabidopsis thaliana GN=CYP71A16
PE=2 SV=1
Length = 497
Score = 85 bits (208), Expect = 2e-015
Identities = 48/171 (28%), Positives = 85/171 (49%), Gaps = 8/171 (4%)
Frame = +1
Query: 985 YFAGQETTSVLLVWTMILLSQHQDWQARAREEVKQVFGDKE----PDTEGLNHLKTMTMI 1152
+ TTS ++ W M L ++ + + ++E++ V + E +N+LK +
Sbjct: 297 FLGSTTTTSAVIEWAMTRLMRNPECLKKLQDEIRSVSKMNSYVSGKEVENMNYLKA---V 353
Query: 1153 INEVLRLYPPVTQL-SRTIHKEMKLGDLTLPGGVHISLPIMLVQRDTQLWGNNAAEFNPE 1329
I EVLRL+PP+ L R + +++KL + G + + +QRDT WG++A EF PE
Sbjct: 354 IKEVLRLHPPLPLLVPRLLSEDVKLKGYDITAGTQVIINAWAIQRDTATWGSDAQEFRPE 413
Query: 1330 RFKDGVSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRFSFEL 1482
R D + PF G R+C G + A + +A +++RF + +
Sbjct: 414 RHFDSTWDFVGRNFKYIPFGAGRRLCPGIGLGSVMASVTLANLVKRFDWRV 464
>sp|Q9T0K0|C71AJ_ARATH Cytochrome P450 71A19 OS=Arabidopsis thaliana GN=CYP71A19
PE=2 SV=1
Length = 490
Score = 81 bits (198), Expect = 2e-014
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 8/171 (4%)
Frame = +1
Query: 985 YFAGQETTSVLLVWTMILLSQHQDWQARAREEV----KQVFGDKEPDTEGLNHLKTMTMI 1152
+ AG T+ L W M L ++ + +EE+ +Q E + E +++L+ +
Sbjct: 291 FLAGTATSLSFLEWAMTELMRNPKVMKKLQEEIRSSSRQGLFVTEKEAEKMDYLQA---V 347
Query: 1153 INEVLRLYPPV-TQLSRTIHKEMKLGDLTLPGGVHISLPIMLVQRDTQLWGNNAAEFNPE 1329
I E LRL PP + R +++ L +P G + + +QRDT WG +A EF PE
Sbjct: 348 IKEALRLRPPAPLMVPRVFSEDVTLKGYNIPAGTQVIINAWAIQRDTTTWGIDAEEFRPE 407
Query: 1330 RFKDGVSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILQRFSFEL 1482
R D + F PF G RIC G F + +A I++RF++ +
Sbjct: 408 RHLDSILDFQGQDFKFIPFGSGKRICPGIGFTSALIGVTLANIVKRFNWRM 458
>sp|Q9HCS2|CP4FC_HUMAN Cytochrome P450 4F12 OS=Homo sapiens GN=CYP4F12 PE=1
SV=1
Length = 524
Score = 77 bits (189), Expect = 3e-013
Identities = 43/134 (32%), Positives = 72/134 (53%), Gaps = 6/134 (4%)
Frame = +2
Query: 281 SSHMLKTYGRTFFTWRG-TIPTITITDPEQIKEVFN-KVYDFPKPHTFP--LSNLIVSGL 448
S+ M TY + F W G IP I + P+ I+ + N PK + F L + G+
Sbjct: 77 STQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGI 136
Query: 449 FSYDGDKWSKHRRIINPAFHLQKIKNMVPVFHQSCNEVIDKWDRIVSDKGSSCEVDVWPG 628
GDKWS+HRR++ PAFH +K+ + +F++S N ++DKW + S+ S +D++
Sbjct: 137 LLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASE--GSSRLDMFEH 194
Query: 629 LMSITEDVISRTAF 670
+ +T D + + F
Sbjct: 195 ISLMTLDSLQKCIF 208
>sp|P51870|CP4F5_RAT Cytochrome P450 4F5 OS=Rattus norvegicus GN=Cyp4f5 PE=2
SV=1
Length = 526
Score = 72 bits (175), Expect = 1e-011
Identities = 51/183 (27%), Positives = 86/183 (46%), Gaps = 10/183 (5%)
Frame = +2
Query: 284 SHMLKTYGRTFFTWRG-TIPTITITDPEQIKEVFN-KVYDFPKPHTFP--LSNLIVSGLF 451
+ M +T+ W G IP + + DP + + PK TF L + GLF
Sbjct: 78 TEMGQTFRDIHLCWLGPVIPVLRLVDPAFVAPLLQAPALVAPKDTTFLRFLKPWLGDGLF 137
Query: 452 SYDGDKWSKHRRIINPAFHLQKIKNMVPVFHQSCNEVIDKWDRIVSDKGSSCEVDVWPGL 631
GDKWS+HRR++ PAFH +K V +F+QS N + KW + + S ++++ +
Sbjct: 138 LSSGDKWSRHRRLLTPAFHFDILKPYVKIFNQSVNIMHAKWKHLCLE--GSARLEMFENI 195
Query: 632 MSITEDVISRTAFG---SSYKDGQRIFELQTELAQLIIQAFSKSYI-PGYRYLPTKDNRR 799
+T D + + FG + + EL+ LII+ + ++ + Y T D RR
Sbjct: 196 SLMTLDSLQKCLFGFDSNCQESPSEYISAILELSSLIIKRSQQLFLYLDFLYYRTADGRR 255
Query: 800 LKQ 808
++
Sbjct: 256 FRK 258
>sp|Q9HBI6|CP4FB_HUMAN Cytochrome P450 4F11 OS=Homo sapiens GN=CYP4F11 PE=2
SV=3
Length = 524
Score = 69 bits (168), Expect = 7e-011
Identities = 41/133 (30%), Positives = 70/133 (52%), Gaps = 6/133 (4%)
Frame = +2
Query: 284 SHMLKTYGRTFFTWRG-TIPTITITDPEQIKEVFN-KVYDFPKPHTFP--LSNLIVSGLF 451
+ ++ TY + F W G T P + + P+ I+ + + PK F L + GL
Sbjct: 78 TQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLL 137
Query: 452 SYDGDKWSKHRRIINPAFHLQKIKNMVPVFHQSCNEVIDKWDRIVSDKGSSCEVDVWPGL 631
GDKWS+HRR++ PAFH +K + +F++S N + DKW R+ S+ S +D++ +
Sbjct: 138 LSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASE--GSARLDMFEHI 195
Query: 632 MSITEDVISRTAF 670
+T D + + F
Sbjct: 196 SLMTLDSLQKCVF 208
>sp|Q9EP75|CP4FE_MOUSE Leukotriene-B4 omega-hydroxylase 3 OS=Mus musculus
GN=Cyp4f14 PE=2 SV=1
Length = 524
Score = 69 bits (167), Expect = 1e-010
Identities = 41/140 (29%), Positives = 68/140 (48%), Gaps = 20/140 (14%)
Frame = +2
Query: 284 SHMLKTYGRTFFTWRG-TIPTITITDPEQIKEVFNK----------VYDFPKPHTFPLSN 430
+ ++ TY + F W G +P IT+ + ++ + N Y KP
Sbjct: 78 TRLVGTYPQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYSILKP------- 130
Query: 431 LIVSGLFSYDGDKWSKHRRIINPAFHLQKIKNMVPVFHQSCNEVIDKWDRIVSDKGSSCE 610
+ GL GDKWS+HRR++ PAFH +K V +F+ S N + KW R++SD S
Sbjct: 131 WLGDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQRLISD--GSAR 188
Query: 611 VDVWPGLMSITEDVISRTAF 670
+D++ + +T D + + F
Sbjct: 189 LDMFEHVSLMTLDSLQKCVF 208
>sp|P33274|CP4F1_RAT Cytochrome P450 4F1 OS=Rattus norvegicus GN=Cyp4f1 PE=2
SV=1
Length = 524
Score = 66 bits (160), Expect = 6e-010
Identities = 40/140 (28%), Positives = 68/140 (48%), Gaps = 20/140 (14%)
Frame = +2
Query: 284 SHMLKTYGRTFFTWRG-TIPTITITDPEQIKEVFNK----------VYDFPKPHTFPLSN 430
+ ++ TY + F W G +P IT+ + ++ + N Y KP
Sbjct: 78 TRLVGTYPQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYTILKP------- 130
Query: 431 LIVSGLFSYDGDKWSKHRRIINPAFHLQKIKNMVPVFHQSCNEVIDKWDRIVSDKGSSCE 610
+ GL GDKWS+HRR++ PAFH +K V +F+ S N + KW R++S+ S
Sbjct: 131 WLGDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWKRLISE--GSSR 188
Query: 611 VDVWPGLMSITEDVISRTAF 670
+D++ + +T D + + F
Sbjct: 189 LDMFEHVSLMTLDSLQKCVF 208
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,727,594,170
Number of Sequences: 518415
Number of Extensions: 61727594170
Number of Successful Extensions: 397900902
Number of sequences better than 0.0: 0
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