BLASTX 7.6.2
Query= UN14676 /QuerySize=1436
(1435 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9T0K7|HIBC6_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like pro... 710 1e-203
sp|Q9LK08|HIBC7_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like pro... 632 2e-180
sp|Q9SHJ8|HIBC8_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like pro... 184 1e-045
sp|Q8RXN4|HIBC5_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like pro... 172 8e-042
sp|Q6NVY1|HIBCH_HUMAN 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 168 1e-040
sp|Q8QZS1|HIBCH_MOUSE 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 167 2e-040
sp|Q5XIE6|HIBCH_RAT 3-hydroxyisobutyryl-CoA hydrolase, mitochond... 165 1e-039
sp|A2VDC2|HIBCH_XENLA 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 165 1e-039
sp|Q58EB4|HIBCH_DANRE 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 164 2e-039
sp|Q5ZJ60|HIBCH_CHICK 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 163 5e-039
sp|Q28FR6|HIBCH_XENTR 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 162 7e-039
sp|Q2HJ73|HIBCH_BOVIN 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 155 1e-036
sp|Q9LKJ1|HIBC1_ARATH 3-hydroxyisobutyryl-CoA hydrolase 1 OS=Ara... 152 7e-036
sp|Q6NMB0|HIBC3_ARATH Probable 3-hydroxyisobutyryl-CoA hydrolase... 145 8e-034
sp|O74802|HIBCH_SCHPO 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 144 1e-033
sp|Q1PEY5|HIBC2_ARATH Probable 3-hydroxyisobutyryl-CoA hydrolase... 139 6e-032
sp|P28817|HIBCH_YEAST 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 138 2e-031
sp|Q55GS6|HIBCH_DICDI 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 121 2e-026
>sp|Q9T0K7|HIBC6_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like protein 3
OS=Arabidopsis thaliana GN=At4g13360 PE=1 SV=1
Length = 381
Score = 710 bits (1830), Expect = 1e-203
Identities = 355/381 (93%), Positives = 367/381 (96%)
Frame = +1
Query: 136 MAGAGGEDFVKGNVYPNGVAVITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQ 315
MAGAG +DFVKGNV+PNGVA+ITLDRTKALNAMNL+MD+KYKSFLDEWESDPRVKCV+++
Sbjct: 1 MAGAGVDDFVKGNVFPNGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVE 60
Query: 316 GSTPRAFCAGMDIKGVAAEIQKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMG 495
GST RAFCAGMDIKGVAAEIQKDKNTPLVQKVFTAEY+LICAIA YKKPYISLMDGITMG
Sbjct: 61 GSTSRAFCAGMDIKGVAAEIQKDKNTPLVQKVFTAEYTLICAIAAYKKPYISLMDGITMG 120
Query: 496 FGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRIS 675
FGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRIS
Sbjct: 121 FGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRIS 180
Query: 676 TPSDALFVGLGTHYVPSENLASLKEAILSANLSEDPNQDIQATLSKYSGNTESEAHLKSL 855
PSDALFVGLGTHYVPSE LASLKEAILSANLSEDPNQDIQATLSKYS N ESEAHLKSL
Sbjct: 181 APSDALFVGLGTHYVPSEKLASLKEAILSANLSEDPNQDIQATLSKYSSNPESEAHLKSL 240
Query: 856 LPQIESAFSSNKSVKETIEELKKYQESTEPSVVEWATEALKGLEKGAPFSLYLTQKYFSN 1035
LP IESAFSSNKS+KETIEELKKYQ+STE SVVEWA EALKGLEKGAPFSLYLTQKYFSN
Sbjct: 241 LPHIESAFSSNKSIKETIEELKKYQQSTESSVVEWANEALKGLEKGAPFSLYLTQKYFSN 300
Query: 1036 VACAKGKAENELATLNGVMKTEYRIALRSALRGDFAEGVRAVLIDKDQNPKWNPASVEEV 1215
VACAK K ENELATLNGVMKTEYRIALRSALRGDFAEGVRAVLIDKDQNPKWNP S+EEV
Sbjct: 301 VACAKSKPENELATLNGVMKTEYRIALRSALRGDFAEGVRAVLIDKDQNPKWNPTSIEEV 360
Query: 1216 DENEVEALFKPLSSEVEELKV 1278
DENEVEALFKPLS EVEELKV
Sbjct: 361 DENEVEALFKPLSPEVEELKV 381
>sp|Q9LK08|HIBC7_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like protein 4,
mitochondrial OS=Arabidopsis thaliana GN=At3g24360 PE=2 SV=1
Length = 418
Score = 632 bits (1629), Expect = 2e-180
Identities = 325/418 (77%), Positives = 357/418 (85%), Gaps = 2/418 (0%)
Frame = +1
Query: 25 KTFVIASVHRIFYPTSYSSTLSSSLHILRFDRRTFSAMAGAGGEDFVKGNVYPNGVAVIT 204
K+ +AS RIF+ + S L + RR FS MA +G ++FVKGNVYPNGVA+IT
Sbjct: 3 KSLSLASA-RIFFSRTSPSFLIPFSKLSVSHRRKFSVMA-SGSDEFVKGNVYPNGVALIT 60
Query: 205 LDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGVAAEIQKD 384
LDR KALNAMNLEMDLKYKS LDEWE DP VKCVV++GST RAFCAGMDIKGV AEI D
Sbjct: 61 LDRPKALNAMNLEMDLKYKSLLDEWEYDPGVKCVVVEGSTSRAFCAGMDIKGVVAEILMD 120
Query: 385 KNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMP 564
KNT LVQKVFTAEYSLIC IAGY+KPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMP
Sbjct: 121 KNTSLVQKVFTAEYSLICKIAGYRKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMP 180
Query: 565 ENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYVPSENLASL 744
ENGIGLFPDVGFSYIAAHSPG GSVGAYLG+TG+RISTPSDALFVGLGTHYVPS L SL
Sbjct: 181 ENGIGLFPDVGFSYIAAHSPGEGSVGAYLGMTGRRISTPSDALFVGLGTHYVPSGKLGSL 240
Query: 745 KEAILSANLSEDPNQDIQATLSKYSGNTESEAHLKSLLPQIESAFSSNKSVKETIEELKK 924
+EAILSA+LS+DP Q IQATLS YS + E+E+HL+ LLPQIESAFS +KSVKETIEELKK
Sbjct: 241 REAILSADLSKDPQQHIQATLSNYSSDPETESHLQMLLPQIESAFSVSKSVKETIEELKK 300
Query: 925 YQESTEPSVVEWATEALKGLEKGAPFSLYLTQKYFSNVACAKGKAENELATLNGVMKTEY 1104
+Q+S+E SV EWA EA++G+EKGAPFSLYLT KYFS VACAKGK N +ATLNGVM TEY
Sbjct: 301 FQQSSEASVAEWANEAVQGIEKGAPFSLYLTHKYFSKVACAKGKTNNAMATLNGVMITEY 360
Query: 1105 RIALRSALRGDFAEGVRAVLIDKDQNPKWNPASVEEVDENEVEALFKPLSSEVEELKV 1278
RIALRSALR DF EGVRAVL DKDQNPKW PAS++EVDE EV+ALF PLS E EEL V
Sbjct: 361 RIALRSALRSDFTEGVRAVLTDKDQNPKWKPASLDEVDETEVDALFMPLSPEFEELNV 418
>sp|Q9SHJ8|HIBC8_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like protein 5
OS=Arabidopsis thaliana GN=At1g06550 PE=2 SV=2
Length = 387
Score = 184 bits (467), Expect = 1e-045
Identities = 122/366 (33%), Positives = 197/366 (53%), Gaps = 24/366 (6%)
Frame = +1
Query: 190 VAVITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGVAA 369
V + TL+R + LN ++ E+ K +L+ WE D + K ++I+G T RAF AG D+K V
Sbjct: 21 VRLTTLNRPRQLNVISPEVVFKLAEYLELWEKDDQTKLILIKG-TGRAFSAGGDLK-VFY 78
Query: 370 EIQKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITERT 549
Q+ K++ L +V Y L I YKK +SL++GI+MG G L ++ V+TE+T
Sbjct: 79 HGQESKDSCL--EVVYRMYWLCYHIHTYKKTQVSLVNGISMGGGAALMVPMKFSVVTEKT 136
Query: 550 VLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYVPSE 729
V A PE G D GFSYI HS G +G +L LTG R++ + + +G+ TH+VPS
Sbjct: 137 VFATPEASFGFHTDCGFSYI--HSRLPGHLGEFLALTGARLN-GKELVAIGMATHFVPSG 193
Query: 730 NLASLKEAILSANLSEDPNQDIQATLSKYSGNTESEAHLKSLLPQIESAFSSNKSVKETI 909
L L+ ++S L +Q+T+ ++S + + + S +SVK+ I
Sbjct: 194 KLMDLEARLVS--LDSGDADVVQSTIEEFSEKVNLDKDSILNKQSVINECFSKESVKQII 251
Query: 910 EELKKYQESTEPSVVEWATEALKGLEKGAPFSLYLTQKYFSNVACAKGKAENELATLNGV 1089
+ ++ EW T +KGL++ +P L + + E TL+
Sbjct: 252 Q---AFEAEASKDGNEWITPVIKGLKRSSPTGLKIV---------LQSIREGRKQTLSDC 299
Query: 1090 MKTEYRIA---LRSALRGDFAEGVRAVLIDKDQNPKWNPASVEEVDENEVEALFKPLSSE 1260
+K E+R+ LR + D EG+RA+ IDKD +PKWNPA+++EVD+ ++ ++FK +
Sbjct: 300 LKKEFRLTLNILRKTISPDMYEGIRALTIDKDNSPKWNPATLDEVDDEKINSVFKLFEDD 359
Query: 1261 VEELKV 1278
EL++
Sbjct: 360 DIELQI 365
>sp|Q8RXN4|HIBC5_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like protein 2,
mitochondrial OS=Arabidopsis thaliana GN=At4g31810 PE=2 SV=1
Length = 409
Score = 172 bits (434), Expect = 8e-042
Identities = 126/387 (32%), Positives = 199/387 (51%), Gaps = 30/387 (7%)
Frame = +1
Query: 121 RTFSAMAGAGGEDF-VKGNVYPNGVA---VITLDRTKALNAMNLEMDLKYKSFLDEWESD 288
R FSA+ D + V G A L+ +LNA++ M + K + WE +
Sbjct: 24 RRFSALPNYSASDADFEDQVLVEGKAKSRAAILNNPSSLNALSAPMVGRLKRLYESWEEN 83
Query: 289 PRVKCVVIQGSTPRAFCAGMDIKGVAAEIQKDKNTPLVQKVFTAEYSLICAIAGYKKPYI 468
P + V+++GS + FC+G D+ + I + NT + F Y + Y KP I
Sbjct: 84 PAISFVLMKGS-GKTFCSGADVLSLYHSI-NEGNTEESKLFFENLYKFVYLQGTYLKPNI 141
Query: 469 SLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAY 648
++MDG+TMG G G+S G +RV T++TVLA PE IG PD G SY + P G +G Y
Sbjct: 142 AIMDGVTMGCGGGISLPGMFRVATDKTVLAHPEVQIGFHPDAGASYYLSRLP--GYLGEY 199
Query: 649 LGLTGKRISTPSDALFVGLGTHYVPSENLASLKEAILSANLSEDPNQDIQATLSKYSGNT 828
L LTG++++ + + GL THY + L ++E I L++DP I+ +L++Y
Sbjct: 200 LALTGQKLN-GVEMIACGLATHYCLNARLPLIEERI-GKLLTDDP-AVIEDSLAQYGDLV 256
Query: 829 ESEAHLKSLLPQIE--SAFSSNKSVKETIEELKKYQESTEPSVVEWATEALKGLEKGAPF 1002
++ S+L +IE + +V+E IE + + S EW + LK +++ +P
Sbjct: 257 YPDS--SSVLHKIELIDKYFGLDTVEEIIEAM---ENEAANSCNEWCKKTLKQIKEASPL 311
Query: 1003 SLYLTQKYFSNVACAKGKAENELATLNGVMKTEYRIAL---RSALRGDFAEGVRAVLIDK 1173
SL +T + E TL+ + EYRI++ + GDF EG+RA L+DK
Sbjct: 312 SLKIT---------LQSIREGRFQTLDQCLTHEYRISICGVSKVVSGDFCEGIRARLVDK 362
Query: 1174 DQNPKWNPASVEEVDENEVEALFKPLS 1254
D PKW+P +E+V ++ V+ F P S
Sbjct: 363 DFAPKWDPPRLEDVSKDMVDCYFTPAS 389
>sp|Q6NVY1|HIBCH_HUMAN 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Homo
sapiens GN=HIBCH PE=1 SV=2
Length = 386
Score = 168 bits (424), Expect = 1e-040
Identities = 114/281 (40%), Positives = 162/281 (57%), Gaps = 25/281 (8%)
Frame = +1
Query: 196 VITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGVA-AE 372
VITL+R K LNA+ L M + L +WE DP ++I+G+ +AFCAG DI+ ++ AE
Sbjct: 48 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAE 107
Query: 373 IQKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITERTV 552
K K P+ F EY L A+ +KPY++L+ GITMG G+GLS HG++RV TE+ +
Sbjct: 108 KAKQKIAPV---FFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCL 164
Query: 553 LAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYVPSEN 732
AMPE IGLFPDVG Y G +G +L LTG R+ D G+ TH+V SE
Sbjct: 165 FAMPETAIGLFPDVGGGYFLPRLQ--GKLGYFLALTGFRLK-GRDVYRAGIATHFVDSEK 221
Query: 733 LASLKEAILSANLSEDPNQDIQATLSKYSGNTESEAH------LKSLLPQIESAFSSNKS 894
LA L+E +L+ L ++I + L Y +TES+ L+ + +I S FS+N +
Sbjct: 222 LAMLEEDLLA--LKSPSKENIASVLENY--HTESKIDRDKSFILEEHMDKINSCFSAN-T 276
Query: 895 VKETIEELKKYQESTEPSVVEWATEALKGLEKGAPFSLYLT 1017
V+E IE L++ S +A E LK + K +P SL +T
Sbjct: 277 VEEIIENLQQDGSS-------FALEQLKVINKMSPTSLKIT 310
>sp|Q8QZS1|HIBCH_MOUSE 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Mus
musculus GN=Hibch PE=1 SV=1
Length = 385
Score = 167 bits (422), Expect = 2e-040
Identities = 102/247 (41%), Positives = 147/247 (59%), Gaps = 12/247 (4%)
Frame = +1
Query: 196 VITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGVAAEI 375
VITL+R K LNA++L M + L WE DP ++I+G+ +AFCAG DIK ++
Sbjct: 47 VITLNRPKFLNALSLNMIRQIYPQLKTWEQDPDTFLIIIKGAGGKAFCAGGDIKALSEAK 106
Query: 376 QKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVL 555
+ +N L Q +F EY L AIA +KPY++L+DGITMG G+GLS HG++RV TER++
Sbjct: 107 KARQN--LTQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLF 164
Query: 556 AMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYVPSENL 735
AMPE GIGLFPDVG Y G +G +L LTG R+ D G+ TH+V SE L
Sbjct: 165 AMPETGIGLFPDVGGGYFLPRLQ--GKLGYFLALTGYRLK-GRDVHRAGIATHFVDSEKL 221
Query: 736 ASLKEAILSANLSEDPNQDIQATLSKYSGNTESEAH----LKSLLPQIESAFSSNKSVKE 903
L+E +L+ L +D+ L Y ++ + + + +I S FS+N +V++
Sbjct: 222 RVLEEELLA--LKSPSAEDVAGVLESYHAKSKMDQDKSIIFEEHMDKINSCFSAN-TVEQ 278
Query: 904 TIEELKK 924
IE L++
Sbjct: 279 IIENLRQ 285
>sp|Q5XIE6|HIBCH_RAT 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Rattus
norvegicus GN=Hibch PE=1 SV=2
Length = 385
Score = 165 bits (416), Expect = 1e-039
Identities = 103/247 (41%), Positives = 148/247 (59%), Gaps = 12/247 (4%)
Frame = +1
Query: 196 VITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGVAAEI 375
VITL+R K LNA++L M + L +WE DP ++I+G+ +AFCAG DIK + +E
Sbjct: 47 VITLNRPKLLNALSLNMIRQIYPQLKKWERDPDTFLIIIKGAGGKAFCAGGDIKAL-SEA 105
Query: 376 QKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVL 555
+K T L Q +F EY L AIA +KPY++L+DGITMG G+GLS HG++RV TER++
Sbjct: 106 KKAGQT-LSQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLF 164
Query: 556 AMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYVPSENL 735
AMPE GIGLFPDVG Y G +G +L LTG R+ D G+ TH+V SE L
Sbjct: 165 AMPETGIGLFPDVGGGYFLPRLQ--GKLGYFLALTGFRLK-GRDVHRAGIATHFVDSEKL 221
Query: 736 ASLKEAILSANLSEDPNQDIQATLSKYSGNT----ESEAHLKSLLPQIESAFSSNKSVKE 903
L+E +L+ L +D+ L Y + + + + +I S FS+N +V++
Sbjct: 222 HVLEEELLA--LKSPSAEDVAGVLESYHAKSKMGQDKSIIFEEHMDKINSCFSAN-TVEQ 278
Query: 904 TIEELKK 924
+E L++
Sbjct: 279 ILENLRQ 285
>sp|A2VDC2|HIBCH_XENLA 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
OS=Xenopus laevis GN=hibch PE=2 SV=1
Length = 385
Score = 165 bits (416), Expect = 1e-039
Identities = 117/300 (39%), Positives = 162/300 (54%), Gaps = 22/300 (7%)
Frame = +1
Query: 196 VITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGV--AA 369
VITL+R KALNA+NL M + L WE DP V+I+G+ +AFCAG DI+ V A
Sbjct: 47 VITLNRPKALNALNLGMIRQIYPQLKLWEEDPETYLVIIKGAGGKAFCAGGDIRAVTDAG 106
Query: 370 EIQKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITERT 549
++ L Q F EY L AI KKPY++++DGITMG G+GLS HG +RV +E+T
Sbjct: 107 KV----GDRLAQDFFREEYILNNAIGTCKKPYVAVIDGITMGGGVGLSVHGHFRVASEKT 162
Query: 550 VLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYVPSE 729
+ AMPE IGLFPDVG Y G +G YL LTG R+ SD G+ TH+V SE
Sbjct: 163 LFAMPETAIGLFPDVGGGYFLPRLT--GKLGLYLALTGFRLK-GSDVQKAGIATHFVESE 219
Query: 730 NLASLKEAILSANLSEDPN-QDIQATLSKYSGNTESEAH-LKSLLPQIESAFSSNKSVKE 903
L+SL++ +++ N D+ + K S + + L + +I S FS N +V+E
Sbjct: 220 KLSSLEQDLVAMKSPSKENVADVLDSYQKKSYAAQDKPFVLAENMDKINSLFSGN-TVEE 278
Query: 904 TIEELK--------KYQESTEPSVVEWATEALKGLEKGAPFSL--YLTQKYFSNVACAKG 1053
+E LK K ++ + L++GA SL LT +Y + AC G
Sbjct: 279 IMENLKCDGSSFAMKQLQTLSTMSPTSLKITFRQLKEGASMSLQEVLTMEYRLSQACMNG 338
>sp|Q58EB4|HIBCH_DANRE 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Danio
rerio GN=hibch PE=2 SV=1
Length = 382
Score = 164 bits (413), Expect = 2e-039
Identities = 110/278 (39%), Positives = 154/278 (55%), Gaps = 14/278 (5%)
Frame = +1
Query: 103 ILRFDRRTFSAMAGAGGEDFVKGNVYPNGVAVITLDRTKALNAMNLEMDLKYKSFLDEWE 282
+ R R M+ G + + V G VITL+R KALNA+ L M L +W+
Sbjct: 15 VCRLQRIHGHMMSSKAGSEVLFEKVGKAG--VITLNRPKALNALTLNMIRHIYPQLKKWD 72
Query: 283 SDPRVKCVVIQGSTPRAFCAGMDIKGVAAEIQKDKNTPLVQKVFTAEYSLICAIAGYKKP 462
D V+I+G+ +AFCAG DI+ + AE K N L Q F EY L I Y+KP
Sbjct: 73 KDSETDIVIIKGAGEKAFCAGGDIRAI-AEAGKAGNL-LSQVFFREEYILNNTIGTYQKP 130
Query: 463 YISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVG 642
Y++L++GITMG G+GLS HG++RV TE+T+ AMPE GIGLFPDVG Y G +G
Sbjct: 131 YVALINGITMGGGVGLSVHGQFRVATEKTLFAMPETGIGLFPDVGGGYFLPRLQ--GKLG 188
Query: 643 AYLGLTGKRISTPSDALFVGLGTHYVPSENLASLKEAILSANLSEDPNQDIQATLSKYSG 822
+L LTG R+ D VG+ TH+V SE + SL++ ++ +L D+ L Y
Sbjct: 189 LFLALTGFRLK-GRDVQRVGVATHFVQSEKIESLEKDLV--DLKSPSISDVAQLLDSYQE 245
Query: 823 NTESEAHLKSLLPQ----IESAFSSNKSVKETIEELKK 924
+ +A +L + I+ FS+ SV+E +E LKK
Sbjct: 246 QSHLDAEKPFVLQEQTEAIDRLFSAG-SVEEIVENLKK 282
>sp|Q5ZJ60|HIBCH_CHICK 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
OS=Gallus gallus GN=HIBCH PE=2 SV=1
Length = 385
Score = 163 bits (410), Expect = 5e-039
Identities = 100/250 (40%), Positives = 146/250 (58%), Gaps = 12/250 (4%)
Frame = +1
Query: 187 GVAVITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGVA 366
G +ITL+R K LNA++ +M + + WE DP ++I+G+ +AFCAG D++ +
Sbjct: 44 GAGIITLNRPKVLNALSFKMIQQIYPQIKAWEQDPETFLIIIKGTGEKAFCAGGDVRAI- 102
Query: 367 AEIQKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITER 546
A+ K +T + + F EY L AI KKPY++L+DGITMG G+GLS HG +RV TE+
Sbjct: 103 ADAGKAGDT-MTRDYFREEYRLDNAIGTCKKPYVALIDGITMGGGVGLSVHGHFRVATEK 161
Query: 547 TVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYVPS 726
TV AMPE IGLFPDVG Y G +G L LTG R+ D L G+ TH+V S
Sbjct: 162 TVFAMPETAIGLFPDVGGGYFLPRL--SGKIGHLLALTGFRLK-GRDVLKAGIATHFVES 218
Query: 727 ENLASLKEAILSANLSEDPNQDIQATLSKYSGNT----ESEAHLKSLLPQIESAFSSNKS 894
L L++ +++ L ++I L+ Y T E E L + +I S FS+N S
Sbjct: 219 GKLPELEKDLIA--LKSPSKENIADLLNSYHMQTKIDQEKEFVLDEHMERINSIFSAN-S 275
Query: 895 VKETIEELKK 924
++E +++LK+
Sbjct: 276 MEEIVQKLKQ 285
Score = 66 bits (160), Expect = 5e-010
Identities = 34/67 (50%), Positives = 47/67 (70%), Gaps = 2/67 (2%)
Frame = +1
Query: 1060 ENELATLNGVMKTEYRIALRSALRG-DFAEGVRAVLIDKDQNPKWNPASVEEVDENEVEA 1236
E +L V EYR++ ++ +RG DF EGVRAVLIDKDQ+P+W PA++EEV + V+
Sbjct: 315 EGATMSLQDVFTMEYRLS-QACMRGHDFYEGVRAVLIDKDQSPRWKPAALEEVSDEFVDN 373
Query: 1237 LFKPLSS 1257
FKPL +
Sbjct: 374 CFKPLGN 380
>sp|Q28FR6|HIBCH_XENTR 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
OS=Xenopus tropicalis GN=hibch PE=2 SV=1
Length = 385
Score = 162 bits (409), Expect = 7e-039
Identities = 107/247 (43%), Positives = 139/247 (56%), Gaps = 14/247 (5%)
Frame = +1
Query: 196 VITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGVA-AE 372
VITL+R KALNA+NL M L WE DP V+I+G +AFCAG DI+ V A
Sbjct: 47 VITLNRPKALNALNLGMIRLIYPQLGLWEEDPETYLVIIKGVGGKAFCAGGDIRAVTDAG 106
Query: 373 IQKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITERTV 552
D+ L Q F EY L AI YKKPY++L+DGITMG G+GLS HG +RV +E T+
Sbjct: 107 KAGDR---LAQDFFREEYILNNAIGTYKKPYVALIDGITMGGGVGLSVHGHFRVASENTL 163
Query: 553 LAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYVPSEN 732
AMPE IGLFPDVG Y P G +G YL LTG R+ SD G+ TH+V SE
Sbjct: 164 FAMPETAIGLFPDVGGGYFLPRLP--GKLGLYLALTGFRLK-GSDVQKAGIATHFVESEK 220
Query: 733 LASLKEAILSANLSEDPNQDIQATLSKYSGNT----ESEAHLKSLLPQIESAFSSNKSVK 900
+ SL++ +++ N + L Y + + L L +I S FS++ SV+
Sbjct: 221 IPSLEQDLVAMKCPSKEN--VADVLDSYHNKSYAAQDKPFVLAEHLDKINSLFSAS-SVE 277
Query: 901 ETIEELK 921
IE L+
Sbjct: 278 AIIENLR 284
>sp|Q2HJ73|HIBCH_BOVIN 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Bos
taurus GN=HIBCH PE=2 SV=1
Length = 386
Score = 155 bits (390), Expect = 1e-036
Identities = 93/247 (37%), Positives = 147/247 (59%), Gaps = 12/247 (4%)
Frame = +1
Query: 196 VITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGVAAEI 375
VITL+R + LN + L M + + L +WE DP+ ++I+G+ +AFCAG DI+ ++
Sbjct: 48 VITLNRPRFLNTLTLGMIRQIYAQLKKWEQDPKTFLIIIKGAGEKAFCAGGDIRALSE-- 105
Query: 376 QKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVL 555
++ N ++Q +F EY L AI +KPYI+L+ GITMG G+G+S HG++RV TE++V
Sbjct: 106 ARNTNQKMLQDLFREEYILNNAIDSCQKPYIALIHGITMGGGVGVSVHGQFRVATEKSVF 165
Query: 556 AMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYVPSENL 735
AMPE IGLFPDVG Y G +G +L LTG R+ D G+ TH+V E L
Sbjct: 166 AMPETAIGLFPDVGGGYFLPRLQ--GKLGYFLALTGFRLK-GRDVYTAGIATHFVDFEKL 222
Query: 736 ASLKEAILSANLSEDPNQDIQATLSKYSGNTESEAH----LKSLLPQIESAFSSNKSVKE 903
L+E +L+ L ++I L Y ++++ L+ + +I S FS+N +V++
Sbjct: 223 GMLEEDLLA--LKSPSKENIADVLETYHAKSKTDQDKPFILEEHMDKINSWFSAN-TVEQ 279
Query: 904 TIEELKK 924
++ L++
Sbjct: 280 IVDNLQQ 286
>sp|Q9LKJ1|HIBC1_ARATH 3-hydroxyisobutyryl-CoA hydrolase 1 OS=Arabidopsis
thaliana GN=CHY1 PE=1 SV=1
Length = 378
Score = 152 bits (383), Expect = 7e-036
Identities = 99/267 (37%), Positives = 147/267 (55%), Gaps = 11/267 (4%)
Frame = +1
Query: 184 NGVAVITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGV 363
+ V ++TL+R K LNA++ M + +E DP VK V+++G RAFCAG D+ V
Sbjct: 17 SSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGH-GRAFCAGGDVAAV 75
Query: 364 AAEIQKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITE 543
+I + N L F++EY L +A Y K +S+++GI MG G G+S HGR+R+ TE
Sbjct: 76 VRDINQG-NWRLGANYFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATE 134
Query: 544 RTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYVP 723
TV AMPE +GLFPDVG SY + P G G Y+GLTG R+ ++ L GL TH+VP
Sbjct: 135 NTVFAMPETALGLFPDVGASYFLSRLP--GFFGEYVGLTGARLD-GAEMLACGLATHFVP 191
Query: 724 SENLASLKEAILSANLSEDPN--QDIQATLSKYSGNTESEAHLKSLLPQIESAFSSNKSV 897
S L +L+ + N S DP I +++ + A+ + L I+ F S ++V
Sbjct: 192 STRLTALEADLCRIN-SNDPTFASTILDAYTQHPRLKQQSAYRR--LDVIDRCF-SRRTV 247
Query: 898 KETIEELKKYQESTEPSVVEWATEALK 978
+E I L++ + +ALK
Sbjct: 248 EEIISALEREATQEADGWISATIQALK 274
>sp|Q6NMB0|HIBC3_ARATH Probable 3-hydroxyisobutyryl-CoA hydrolase 3
OS=Arabidopsis thaliana GN=At2g30660 PE=2 SV=1
Length = 378
Score = 145 bits (365), Expect = 8e-034
Identities = 93/248 (37%), Positives = 138/248 (55%), Gaps = 9/248 (3%)
Frame = +1
Query: 184 NGVAVITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGV 363
+ V ++TL+R K LNA+ M + +E DP VK V+++G RAFCAG D+ V
Sbjct: 13 SSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQ-GRAFCAGGDVPPV 71
Query: 364 AAEIQKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITE 543
+ + K L F +Y+L +A Y KP +S+++GI MG G G+S HGR+R+ TE
Sbjct: 72 VQNMVQGK-WRLGADFFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATE 130
Query: 544 RTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYVP 723
TV AMPE +GLFPDVG SY + P G G Y+GLTG R+ ++ L GL TH+VP
Sbjct: 131 NTVFAMPETSLGLFPDVGASYFLSRLP--GFFGEYVGLTGARLD-GAELLACGLATHFVP 187
Query: 724 SENLASLKEAILSANLSEDPNQDIQATLSKYSGNTE-SEAHLKSLLPQIESAFSSNKSVK 900
S L +L+ + S DP+ + L Y+ + + L I+ F S ++++
Sbjct: 188 STRLTALETDLCKVG-SSDPS-FVSTILDAYTQHPHLKQKSAYHRLDVIDRCF-SKRTME 244
Query: 901 ETIEELKK 924
E I L++
Sbjct: 245 EIISALER 252
>sp|O74802|HIBCH_SCHPO 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
OS=Schizosaccharomyces pombe GN=ehd3 PE=2 SV=1
Length = 429
Score = 144 bits (363), Expect = 1e-033
Identities = 98/288 (34%), Positives = 150/288 (52%), Gaps = 11/288 (3%)
Frame = +1
Query: 184 NGVAVITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGV 363
NG + TL+R K LNA+N++M L E K ++++G+ R+F +G DIK
Sbjct: 64 NGARIFTLNRPKVLNAINVDMIDSILPKLVSLEESNLAKVIILKGN-GRSFSSGGDIKAA 122
Query: 364 AAEIQKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITE 543
A IQ D P V+ F EY L +A Y+KP ++LM+GITMG G GL+ H +R+ E
Sbjct: 123 ALSIQ-DGKLPEVRHAFAQEYRLSHTLATYQKPVVALMNGITMGGGSGLAMHVPFRIACE 181
Query: 544 RTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYVP 723
T+ AMPE GIG F DV S+ + P G G YLGLT +I D L G+ TH+VP
Sbjct: 182 DTMFAMPETGIGYFTDVAASFFFSRLP--GYFGTYLGLT-SQIVKGYDCLRTGIATHFVP 238
Query: 724 SENLASLKEAILSANLSEDPNQDIQATLSKYS--GNTESEAHLKSLLPQIESAFSSNKSV 897
L++ + N S+ I T+ +++ ++ ++ I F N +V
Sbjct: 239 KHMFPHLEDRLAELNTSD--ISKINNTILEFAEFASSSPPTFTPDVMDVINKCFCKNDTV 296
Query: 898 KETIEELKKYQESTEPSVVEWATEALKGLEKGAPFSLYLTQKYFSNVA 1041
+ I LK+Y +T ++ E+A +K L +P S+ +T + + A
Sbjct: 297 -DIIRALKEYASNTS-ALAEFAKSTVKTLYSKSPTSIAVTNRLIKSAA 342
>sp|Q1PEY5|HIBC2_ARATH Probable 3-hydroxyisobutyryl-CoA hydrolase 2
OS=Arabidopsis thaliana GN=At2g30650 PE=2 SV=1
Length = 378
Score = 139 bits (349), Expect = 6e-032
Identities = 91/250 (36%), Positives = 135/250 (54%), Gaps = 13/250 (5%)
Frame = +1
Query: 184 NGVAVITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGSTPRAFCAGMDIKGV 363
+ V ++T +R K LNA++ M + +E DP VK VV++G RAF AG DI +
Sbjct: 13 SSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQ-GRAFSAGGDIPPI 71
Query: 364 AAEIQKDKNTPLVQ--KVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVI 537
+I + K L++ F Y+L ++ Y+KP +S+++GI MG G GLS +GR+R+
Sbjct: 72 VRDILQGK---LIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIA 128
Query: 538 TERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHY 717
TE TV AMPE +GLFPDVG SY + P G G Y+GLTG R+ ++ L GL TH+
Sbjct: 129 TENTVFAMPETALGLFPDVGASYFLSRLP--GFFGEYVGLTGARLD-GAEMLACGLATHF 185
Query: 718 VPSENLASLKEAILSANLSEDPNQD-IQATLSKYSGNTESEAHLKSLLPQIESAFSSNKS 894
VPS +L +L+ + S NQ I L Y+ H + S ++
Sbjct: 186 VPSISLTALEAELYKVGSS---NQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRT 242
Query: 895 VKETIEELKK 924
V+E L++
Sbjct: 243 VEEIFSALER 252
>sp|P28817|HIBCH_YEAST 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
OS=Saccharomyces cerevisiae GN=EHD3 PE=1 SV=2
Length = 500
Score = 138 bits (345), Expect = 2e-031
Identities = 87/203 (42%), Positives = 117/203 (57%), Gaps = 9/203 (4%)
Frame = +1
Query: 196 VITLDRTKALNAMNLEMDLKYKSFLDEWESDPRVKCVVIQGST-PRAFCAGMDIKGVAAE 372
VITL+R K LNA+N EM L+E+ V+++ S PR+FCAG D+ VA
Sbjct: 49 VITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDVATVAI- 107
Query: 373 IQKDKNTPLVQKVFTAEYSLICAIAGYKKPYISLMDGITMGFGLGLSGHGRYRVITERTV 552
+K K FT EYSL IA Y KP ++ MDGITMG G+GLS H +R+ TE T
Sbjct: 108 FNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHTPFRIATENTK 167
Query: 553 LAMPENGIGLFPDVGFSY----IAAHSPGGGSVGAYLGLTGKRISTPSDALFVGLGTHYV 720
AMPE IG FPDVG ++ I + + YL LTG+ + T +DA +GL +HYV
Sbjct: 168 WAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGE-VVTGADAYMLGLASHYV 226
Query: 721 PSENLASLKEAI--LSANLSEDP 783
SENL +L++ + +S + DP
Sbjct: 227 SSENLDALQKRLGEISPPFNNDP 249
>sp|Q55GS6|HIBCH_DICDI 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
OS=Dictyostelium discoideum GN=hibch PE=3 SV=1
Length = 381
Score = 121 bits (302), Expect = 2e-026
Identities = 81/218 (37%), Positives = 119/218 (54%), Gaps = 14/218 (6%)
Frame = +1
Query: 304 VVIQGSTPRAFCAGMDIKGV-----AAEIQKDKNTPLVQKVFTAEYSLICAIAGYKKPYI 468
+V++G+ +AFCAG DI+ + E QK K + F EY L I +
Sbjct: 72 IVMKGAGEKAFCAGGDIRAIYDYKQLNEEQKSKTNDIGDLFFREEYILNNLIGTNPIAQV 131
Query: 469 SLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAY 648
S+ +G MG G+GLS HG++RV TE TV AMPE GIG F DVG SY P + G Y
Sbjct: 132 SIYNGFAMGGGIGLSVHGKFRVATENTVFAMPETGIGFFCDVGGSYFLPRLP--NNYGMY 189
Query: 649 LGLTGKRISTPSDALFVGLGTHYVPSENLASLKEAILSANLSEDP-NQDIQATLSKYSGN 825
L LTG ++ ++ G+ TH+V +E++ +L++ I E+P +Q I + L+KY
Sbjct: 190 LALTGSKLK-GNNVYLAGVATHFVSNEHIQALEKEIEEC---ENPTSQTINSILTKYHDK 245
Query: 826 TESEAH-LKSLLPQIESAFSSNKSVKETIEELKKYQES 936
++S ++ L IE F N SVKE E+L+ + S
Sbjct: 246 SKSTSNEYNDNLGDIERIFGKN-SVKEIFEQLELLENS 282
Score = 67 bits (161), Expect = 4e-010
Identities = 30/67 (44%), Positives = 47/67 (70%)
Frame = +1
Query: 1066 ELATLNGVMKTEYRIALRSALRGDFAEGVRAVLIDKDQNPKWNPASVEEVDENEVEALFK 1245
+L +L ++ E+RI+ + DF EGVRA+L+DKD+NPKW P S++++D+ V + FK
Sbjct: 312 KLPSLAKCLEMEFRISQHFLEKPDFFEGVRALLVDKDKNPKWLPPSIDQIDQTLVNSYFK 371
Query: 1246 PLSSEVE 1266
PLS+ E
Sbjct: 372 PLSNNKE 378
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,727,594,170
Number of Sequences: 518415
Number of Extensions: 61727594170
Number of Successful Extensions: 397900902
Number of sequences better than 0.0: 0
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