BLASTX 7.6.2
Query= UN14810 /QuerySize=1587
(1586 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|A5A6H9|ODBA_PANTR 2-oxoisovalerate dehydrogenase subunit alph... 409 4e-113
sp|P11178|ODBA_BOVIN 2-oxoisovalerate dehydrogenase subunit alph... 408 6e-113
sp|P12694|ODBA_HUMAN 2-oxoisovalerate dehydrogenase subunit alph... 408 6e-113
sp|Q8HXY4|ODBA_MACFA 2-oxoisovalerate dehydrogenase subunit alph... 406 2e-112
sp|P11960|ODBA_RAT 2-oxoisovalerate dehydrogenase subunit alpha,... 406 4e-112
sp|P50136|ODBA_MOUSE 2-oxoisovalerate dehydrogenase subunit alph... 405 7e-112
sp|Q54M22|ODBA_DICDI 2-oxoisovalerate dehydrogenase subunit alph... 404 9e-112
sp|Q72GU1|ODBA_THET2 2-oxoisovalerate dehydrogenase subunit alph... 254 1e-066
sp|Q5SLR4|ODBA_THET8 2-oxoisovalerate dehydrogenase subunit alph... 251 1e-065
sp|Q9I1M2|ODBA_PSEAE 2-oxoisovalerate dehydrogenase subunit alph... 215 7e-055
sp|P37940|ODBA_BACSU 2-oxoisovalerate dehydrogenase subunit alph... 203 4e-051
sp|P09060|ODBA_PSEPU 2-oxoisovalerate dehydrogenase subunit alph... 202 8e-051
sp|Q5HGZ1|ODPA_STAAC Pyruvate dehydrogenase E1 component subunit... 190 3e-047
sp|P60089|ODPA_STAAM Pyruvate dehydrogenase E1 component subunit... 190 3e-047
sp|Q820A6|ODPA_STAAN Pyruvate dehydrogenase E1 component subunit... 190 3e-047
sp|Q6GAC1|ODPA_STAAS Pyruvate dehydrogenase E1 component subunit... 190 3e-047
sp|P60090|ODPA_STAAW Pyruvate dehydrogenase E1 component subunit... 190 3e-047
sp|Q6GHZ2|ODPA_STAAR Pyruvate dehydrogenase E1 component subunit... 188 1e-046
sp|Q5HQ76|ODPA_STAEQ Pyruvate dehydrogenase E1 component subunit... 188 1e-046
sp|Q8CPN3|ODPA_STAES Pyruvate dehydrogenase E1 component subunit... 188 1e-046
>sp|A5A6H9|ODBA_PANTR 2-oxoisovalerate dehydrogenase subunit alpha,
mitochondrial OS=Pan troglodytes GN=BCKDHA PE=2 SV=1
Length = 445
Score = 409 bits (1050), Expect = 4e-113
Identities = 190/388 (48%), Positives = 264/388 (68%)
Frame = +1
Query: 247 FPGGKVAFTPEIHFISESNEQRVPCYRVLDDNGQQLTDSRFVPVSEEVAVKMYSDMVTLQ 426
FPG F ++ FI + +P YRV+D GQ + S + +E +K+Y M L
Sbjct: 54 FPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLN 113
Query: 427 MMDNIFYEAQRQGRLSFYATAFGEEAINIASAAALSPQDVIFPQYREPGVLLWRGFTLQE 606
MD I YE+QRQGR+SFY T +GEE ++ SAAAL D++F QYRE GVL++R + L+
Sbjct: 114 TMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLEL 173
Query: 607 FANQCFGNKSDYGKGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAV 786
F QC+GN SD GKGRQMPVHYG + ++ T+S+ +ATQ+P AVGAAY+ K +
Sbjct: 174 FMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVI 233
Query: 787 TFFGDGGSSEGDFHAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGI 966
+FG+G +SEGD HA NFAA +E P++F CRNNG+AISTPTS+Q+R DG+ +G YGI
Sbjct: 234 CYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGI 293
Query: 967 RSIRVDGNDALAMYSAVHEGREMAIREHRPILIEALTYRVGHHSTSDDSTRYRSADEIEW 1146
SIRVDGND A+Y+A E R A+ E++P LIEA+TYR+GHHSTSDDS+ YRS DE+ +
Sbjct: 294 MSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNY 353
Query: 1147 WNKARNPLSRFRTWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVY 1326
W+K +P+SR R ++ S GWW +E E R + +K+++EA AE+ KPN N +FSDVY
Sbjct: 354 WDKQDHPVSRLRHYLLSQGWWDEEQEKAWRKQSRKKVMEAFEQAERKPKPNPNLLFSDVY 413
Query: 1327 DVPPLNLREQELLVRKCVKSHPQDYPSD 1410
P LR+Q+ + + ++++ + YP D
Sbjct: 414 QEMPAQLRKQQESLARHLQTYGEHYPLD 441
>sp|P11178|ODBA_BOVIN 2-oxoisovalerate dehydrogenase subunit alpha,
mitochondrial OS=Bos taurus GN=BCKDHA PE=2 SV=1
Length = 455
Score = 408 bits (1048), Expect = 6e-113
Identities = 190/388 (48%), Positives = 263/388 (67%)
Frame = +1
Query: 247 FPGGKVAFTPEIHFISESNEQRVPCYRVLDDNGQQLTDSRFVPVSEEVAVKMYSDMVTLQ 426
FPG F ++ FI + +P YRV+D GQ + S + +E +K Y M L
Sbjct: 64 FPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEKVLKFYKSMTLLN 123
Query: 427 MMDNIFYEAQRQGRLSFYATAFGEEAINIASAAALSPQDVIFPQYREPGVLLWRGFTLQE 606
MD I YE+QRQGR+SFY T +GEE ++ SAAAL D++F QYRE GVL++R + L+
Sbjct: 124 TMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDDTDLVFGQYREAGVLMYRDYPLEL 183
Query: 607 FANQCFGNKSDYGKGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAV 786
F QC+GN SD GKGRQMPVHYG + ++ T+S+ +ATQ+P AVGAAY+ K +
Sbjct: 184 FMAQCYGNVSDLGKGRQMPVHYGCRERHFVTISSPLATQIPQAVGAAYAAKRANANRVVI 243
Query: 787 TFFGDGGSSEGDFHAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGI 966
+FG+G +SEGD HA NFAA +E P++F CRNNG+AISTPTS+Q+R DG+ +G YGI
Sbjct: 244 CYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGI 303
Query: 967 RSIRVDGNDALAMYSAVHEGREMAIREHRPILIEALTYRVGHHSTSDDSTRYRSADEIEW 1146
SIRVDGND A+Y+A E R A+ E++P LIEA+TYR+GHHSTSDDS+ YRS DE+ +
Sbjct: 304 LSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNY 363
Query: 1147 WNKARNPLSRFRTWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVY 1326
W+K +P+SR R ++S GWW DE E R + +K+++EA AE+ KPN + +FSDVY
Sbjct: 364 WDKQDHPISRLRHHLQSRGWWDDEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLIFSDVY 423
Query: 1327 DVPPLNLREQELLVRKCVKSHPQDYPSD 1410
P LR+Q+ + + ++++ + YP D
Sbjct: 424 QEMPAQLRKQQESLARHLQTYGEHYPLD 451
>sp|P12694|ODBA_HUMAN 2-oxoisovalerate dehydrogenase subunit alpha,
mitochondrial OS=Homo sapiens GN=BCKDHA PE=1 SV=2
Length = 445
Score = 408 bits (1048), Expect = 6e-113
Identities = 189/388 (48%), Positives = 264/388 (68%)
Frame = +1
Query: 247 FPGGKVAFTPEIHFISESNEQRVPCYRVLDDNGQQLTDSRFVPVSEEVAVKMYSDMVTLQ 426
FPG F ++ FI + +P YRV+D GQ + S + +E +K+Y M L
Sbjct: 54 FPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLN 113
Query: 427 MMDNIFYEAQRQGRLSFYATAFGEEAINIASAAALSPQDVIFPQYREPGVLLWRGFTLQE 606
MD I YE+QRQGR+SFY T +GEE ++ SAAAL D++F QYRE GVL++R + L+
Sbjct: 114 TMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLEL 173
Query: 607 FANQCFGNKSDYGKGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAV 786
F QC+GN SD GKGRQMPVHYG + ++ T+S+ +ATQ+P AVGAAY+ K +
Sbjct: 174 FMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVI 233
Query: 787 TFFGDGGSSEGDFHAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGI 966
+FG+G +SEGD HA NFAA +E P++F CRNNG+AISTPTS+Q+R DG+ +G YGI
Sbjct: 234 CYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGI 293
Query: 967 RSIRVDGNDALAMYSAVHEGREMAIREHRPILIEALTYRVGHHSTSDDSTRYRSADEIEW 1146
SIRVDGND A+Y+A E R A+ E++P LIEA+TYR+GHHSTSDDS+ YRS DE+ +
Sbjct: 294 MSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNY 353
Query: 1147 WNKARNPLSRFRTWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVY 1326
W+K +P+SR R ++ S GWW +E E R + +++++EA AE+ KPN N +FSDVY
Sbjct: 354 WDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVY 413
Query: 1327 DVPPLNLREQELLVRKCVKSHPQDYPSD 1410
P LR+Q+ + + ++++ + YP D
Sbjct: 414 QEMPAQLRKQQESLARHLQTYGEHYPLD 441
>sp|Q8HXY4|ODBA_MACFA 2-oxoisovalerate dehydrogenase subunit alpha,
mitochondrial OS=Macaca fascicularis GN=BCKDHA PE=2 SV=1
Length = 445
Score = 406 bits (1043), Expect = 2e-112
Identities = 188/386 (48%), Positives = 263/386 (68%)
Frame = +1
Query: 247 FPGGKVAFTPEIHFISESNEQRVPCYRVLDDNGQQLTDSRFVPVSEEVAVKMYSDMVTLQ 426
FPG F ++ FI + +P YRV+D GQ + S + +E +K+Y M L
Sbjct: 54 FPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLN 113
Query: 427 MMDNIFYEAQRQGRLSFYATAFGEEAINIASAAALSPQDVIFPQYREPGVLLWRGFTLQE 606
MD I YE+QRQGR+SFY T +GEE ++ SAAAL D++F QYRE GVL++R + L+
Sbjct: 114 TMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLEL 173
Query: 607 FANQCFGNKSDYGKGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAV 786
F QC+GN SD GKGRQMPVHYG + ++ T+S+ +ATQ+P AVGAAY+ K +
Sbjct: 174 FMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVI 233
Query: 787 TFFGDGGSSEGDFHAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGI 966
+FG+G +SEGD HA NFAA +E P++F CRNNG+AISTPTS+Q+R DG+ +G YGI
Sbjct: 234 CYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGI 293
Query: 967 RSIRVDGNDALAMYSAVHEGREMAIREHRPILIEALTYRVGHHSTSDDSTRYRSADEIEW 1146
SIRVDGND A+Y+A E R A+ E++P LIEA+TYR+GHHSTSDDS+ YRS DE+ +
Sbjct: 294 MSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNY 353
Query: 1147 WNKARNPLSRFRTWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVY 1326
W+K +P+SR R ++ S GWW +E E R + +K++++A AE+ KPN N +FSDVY
Sbjct: 354 WDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRKKVMKAFEQAERKPKPNPNLLFSDVY 413
Query: 1327 DVPPLNLREQELLVRKCVKSHPQDYP 1404
P LR+Q+ + + ++++ + YP
Sbjct: 414 QEMPAQLRKQQESLARHLQTYGEHYP 439
>sp|P11960|ODBA_RAT 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
(Fragment) OS=Rattus norvegicus GN=Bckdha PE=1 SV=1
Length = 441
Score = 406 bits (1041), Expect = 4e-112
Identities = 188/388 (48%), Positives = 263/388 (67%)
Frame = +1
Query: 247 FPGGKVAFTPEIHFISESNEQRVPCYRVLDDNGQQLTDSRFVPVSEEVAVKMYSDMVTLQ 426
FPG F ++ FI + +P YRV+D GQ + S + +E +K+Y M L
Sbjct: 50 FPGASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVLKLYRSMTLLN 109
Query: 427 MMDNIFYEAQRQGRLSFYATAFGEEAINIASAAALSPQDVIFPQYREPGVLLWRGFTLQE 606
MD I YE+QRQGR+SFY T +GEE ++ SAAAL D++F QYRE GVL++R + L+
Sbjct: 110 TMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALERTDLVFGQYREAGVLMYRDYPLEL 169
Query: 607 FANQCFGNKSDYGKGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAV 786
F QC+GN SD GKGRQMPVHYG + ++ T+S+ +ATQ+P AVGAAY+ K +
Sbjct: 170 FMAQCYGNVSDPGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANQIVI 229
Query: 787 TFFGDGGSSEGDFHAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGI 966
+FG+G +SEGD HA NFAA +E P++F CRNNG+AISTPTS+Q+R DG+ +G YGI
Sbjct: 230 CYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGI 289
Query: 967 RSIRVDGNDALAMYSAVHEGREMAIREHRPILIEALTYRVGHHSTSDDSTRYRSADEIEW 1146
SIRVDGND A+Y+A E R A+ E++P LIEA+TYR+GHHSTSDDS+ YRS DE+ +
Sbjct: 290 MSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNY 349
Query: 1147 WNKARNPLSRFRTWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVY 1326
W+K +P+SR R ++ + GWW +E E R + +K+++EA AE+ KPN + +FSDVY
Sbjct: 350 WDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLLFSDVY 409
Query: 1327 DVPPLNLREQELLVRKCVKSHPQDYPSD 1410
P LR Q+ + + ++++ + YP D
Sbjct: 410 QEMPAQLRRQQESLARHLQTYGEHYPLD 437
>sp|P50136|ODBA_MOUSE 2-oxoisovalerate dehydrogenase subunit alpha,
mitochondrial OS=Mus musculus GN=Bckdha PE=1 SV=1
Length = 442
Score = 405 bits (1039), Expect = 7e-112
Identities = 186/388 (47%), Positives = 264/388 (68%)
Frame = +1
Query: 247 FPGGKVAFTPEIHFISESNEQRVPCYRVLDDNGQQLTDSRFVPVSEEVAVKMYSDMVTLQ 426
FPG F ++ FI + +P YRV+D GQ + S + +E +K Y M L
Sbjct: 51 FPGASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVLKFYRSMTLLN 110
Query: 427 MMDNIFYEAQRQGRLSFYATAFGEEAINIASAAALSPQDVIFPQYREPGVLLWRGFTLQE 606
MD I YE+QR+GR+SFY T +GEE ++ SAAAL D++F QYRE GVL++R + L+
Sbjct: 111 TMDRILYESQREGRISFYMTNYGEEGTHVGSAAALERTDLVFGQYREAGVLMYRDYPLEL 170
Query: 607 FANQCFGNKSDYGKGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAV 786
F +QC+GN +D GKGRQMPVHYG + ++ T+S+ +ATQ+P AVGAAY+ K +
Sbjct: 171 FMSQCYGNVNDPGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRIVI 230
Query: 787 TFFGDGGSSEGDFHAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGI 966
+FG+G +SEGD HA NFAA +E P++F CRNNG+AISTPTS+Q+R DG+ +G YGI
Sbjct: 231 CYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGI 290
Query: 967 RSIRVDGNDALAMYSAVHEGREMAIREHRPILIEALTYRVGHHSTSDDSTRYRSADEIEW 1146
+SIRVDGND A+Y+A E R A+ E++P LIEA+TYR+GHHSTSDDS+ YRS DE+ +
Sbjct: 291 KSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNY 350
Query: 1147 WNKARNPLSRFRTWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVY 1326
W+K +P+SR R ++ + GWW +E E R + +K+++EA AE+ KPN + +FSDVY
Sbjct: 351 WDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLLFSDVY 410
Query: 1327 DVPPLNLREQELLVRKCVKSHPQDYPSD 1410
P LR Q+ + + ++++ + YP D
Sbjct: 411 QEMPAQLRRQQESLARHLQTYGEHYPLD 438
>sp|Q54M22|ODBA_DICDI 2-oxoisovalerate dehydrogenase subunit alpha,
mitochondrial OS=Dictyostelium discoideum GN=bkdA PE=3 SV=1
Length = 441
Score = 404 bits (1038), Expect = 9e-112
Identities = 183/365 (50%), Positives = 260/365 (71%), Gaps = 1/365 (0%)
Frame = +1
Query: 313 VPCYRVLDDNGQQLTDSRFVPVSEEVAVKMYSDMVTLQMMDNIFYEAQRQGRLSFYATAF 492
+PCY ++D G + S+E +KMY+ M+TL +MD+I Y+ QRQGR+SFY T+F
Sbjct: 64 IPCYTIMDQEGVVSKPDQDPNFSKEEVIKMYTTMLTLNVMDSILYDVQRQGRISFYMTSF 123
Query: 493 GEEAINIASAAALSPQDVIFPQYREPGVLLWRGFTLQEFANQCFGNKSDYGKGRQMPVHY 672
GEEAI+I SAAAL D IF QYRE GV +WRGFT+ + NQC N+ D GKGRQMP+H+
Sbjct: 124 GEEAIHIGSAAALEMSDTIFAQYRETGVFMWRGFTINDIINQCCTNEHDLGKGRQMPMHF 183
Query: 673 GSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVTFFGDGGSSEGDFHAALNFAAV 852
GS K+N T+S+ + TQLP AVG++Y+ K+ G++ C + +FG+G +SEGDFHAA+NFAA
Sbjct: 184 GSRKINLQTISSPLTTQLPQAVGSSYAQKLAGEKNCTIVYFGEGAASEGDFHAAMNFAAA 243
Query: 853 MEAPVLFICRNNGWAISTPTSDQFRSDGVVVKG-RAYGIRSIRVDGNDALAMYSAVHEGR 1029
+ P +F CRNN WAISTP+ +Q++ DG+ +G YG+++IRVDGND A+Y+ R
Sbjct: 244 LSTPTIFFCRNNKWAISTPSKEQYKGDGIAGRGPNGYGMKTIRVDGNDIWAVYNVTKLAR 303
Query: 1030 EMAIREHRPILIEALTYRVGHHSTSDDSTRYRSADEIEWWNKARNPLSRFRTWVESNGWW 1209
++A+ E P+LIEA+TYRVGHHSTSDDS+RYR+ +EI W + +NP+SR R ++ GWW
Sbjct: 304 KIAVEEQVPVLIEAMTYRVGHHSTSDDSSRYRTVEEINAWKEGKNPISRLRNYMNHKGWW 363
Query: 1210 SDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVYDVPPLNLREQELLVRKCVKSH 1389
SD E + + + + E++ AEK KP++N +F+DVYD P NL EQ+ + + +K +
Sbjct: 364 SDAQEKETIANARTTVRESLVNAEKQYKPSINEIFTDVYDKPTPNLIEQQKELIEHLKLY 423
Query: 1390 PQDYP 1404
P +YP
Sbjct: 424 PDEYP 428
>sp|Q72GU1|ODBA_THET2 2-oxoisovalerate dehydrogenase subunit alpha OS=Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) GN=TT_C1757 PE=3
SV=1
Length = 367
Score = 254 bits (648), Expect = 1e-066
Identities = 142/351 (40%), Positives = 205/351 (58%), Gaps = 3/351 (0%)
Frame = +1
Query: 325 RVLDDNGQQLTDSRFVPVSEEVAVKMYSDMVTLQMMDNIFYEAQRQGRLSFYATAFGEEA 504
R++ + G+ L D + + E ++Y DM+ +M+D + R G+ SF A A G EA
Sbjct: 17 RLIGEEGEWLGDFP-LDLEGEKLRRLYRDMLAARMLDERYTILIRTGKTSFIAPAAGHEA 75
Query: 505 INIASAAALSPQ-DVIFPQYREPGVLLWRGFTLQEFANQCFGNKSDYGKGRQMPVHYGSN 681
+A A A+ P D +FP YR+ G+ L G L+E Q K+D KGRQMP H GS
Sbjct: 76 AQVAIAHAIRPGFDWVFPYYRDHGLALALGIPLKELFGQMLATKADPNKGRQMPEHPGSK 135
Query: 682 KLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVTFFGDGGSSEGDFHAALNFAAVMEA 861
LN+FTV++ IA+ +P A GAA S+K+ AV FGDG +SEGD++A +NFAAV A
Sbjct: 136 ALNFFTVASPIASHVPPAAGAAISMKLLRTGQVAVCTFGDGATSEGDWYAGINFAAVQGA 195
Query: 862 PVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGIRSIRVDGNDALAMYSAVHEGREMAI 1041
P +F+C NN +AIS Q S + K A+GI VDG D LA Y V E E A
Sbjct: 196 PAVFVCENNFYAISVDYRHQTHSPTIADKAHAFGIPGYLVDGMDVLASYYVVKEAVERAR 255
Query: 1042 REHRPILIEALTYRVGHHSTSDDSTRYRSADEIEWWNKARNPLSRFRTWVESNGWWSDEA 1221
R P L+E YR G HS++DD +RYR +E+ +W K ++P+ RFR ++E+ G W++E
Sbjct: 256 RGEGPSLVELRVYRYGPHSSADDDSRYRPKEEVAFWRK-KDPIPRFRRFLEARGLWNEEW 314
Query: 1222 ESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVYDVPPLNLREQELLVRK 1374
E D+R I+ E+ ++ AE+ MF+DV+ P +L QE L+++
Sbjct: 315 EEDVREEIRAELERGLKEAEEAGPVPPEWMFADVFAEKPWHLLRQEALLKE 365
>sp|Q5SLR4|ODBA_THET8 2-oxoisovalerate dehydrogenase subunit alpha OS=Thermus
thermophilus (strain HB8 / ATCC 27634 / DSM 579) GN=TTHA0229 PE=1 SV=1
Length = 367
Score = 251 bits (640), Expect = 1e-065
Identities = 142/351 (40%), Positives = 203/351 (57%), Gaps = 3/351 (0%)
Frame = +1
Query: 325 RVLDDNGQQLTDSRFVPVSEEVAVKMYSDMVTLQMMDNIFYEAQRQGRLSFYATAFGEEA 504
R++ + G+ L D + + E ++Y DM+ +M+D + R G+ SF A A G EA
Sbjct: 17 RLIGEEGEWLGDFP-LDLEGEKLRRLYRDMLAARMLDERYTILIRTGKTSFIAPAAGHEA 75
Query: 505 INIASAAALSPQ-DVIFPQYREPGVLLWRGFTLQEFANQCFGNKSDYGKGRQMPVHYGSN 681
+A A A+ P D +FP YR+ G+ L G L+E Q K+D KGRQMP H GS
Sbjct: 76 AQVAIAHAIRPGFDWVFPYYRDHGLALALGIPLKELLGQMLATKADPNKGRQMPEHPGSK 135
Query: 682 KLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVTFFGDGGSSEGDFHAALNFAAVMEA 861
LN+FTV++ IA+ +P A GAA S+K+ AV FGDG +SEGD++A +NFAAV A
Sbjct: 136 ALNFFTVASPIASHVPPAAGAAISMKLLRTGQVAVCTFGDGATSEGDWYAGINFAAVQGA 195
Query: 862 PVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGIRSIRVDGNDALAMYSAVHEGREMAI 1041
P +FI NN +AIS Q S + K A+GI VDG D LA Y V E E A
Sbjct: 196 PAVFIAENNFYAISVDYRHQTHSPTIADKAHAFGIPGYLVDGMDVLASYYVVKEAVERAR 255
Query: 1042 REHRPILIEALTYRVGHHSTSDDSTRYRSADEIEWWNKARNPLSRFRTWVESNGWWSDEA 1221
R P L+E YR G HS++DD +RYR +E+ +W K ++P+ RFR ++E+ G W++E
Sbjct: 256 RGEGPSLVELRVYRYGPHSSADDDSRYRPKEEVAFWRK-KDPIPRFRRFLEARGLWNEEW 314
Query: 1222 ESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVYDVPPLNLREQELLVRK 1374
E D+R I+ E+ ++ AE+ MF DV+ P +L QE L+++
Sbjct: 315 EEDVREEIRAELERGLKEAEEAGPVPPEWMFEDVFAEKPWHLLRQEALLKE 365
>sp|Q9I1M2|ODBA_PSEAE 2-oxoisovalerate dehydrogenase subunit alpha
OS=Pseudomonas aeruginosa GN=bkdA1 PE=3 SV=1
Length = 410
Score = 215 bits (547), Expect = 7e-055
Identities = 141/378 (37%), Positives = 198/378 (52%), Gaps = 13/378 (3%)
Frame = +1
Query: 250 PGGKVAFTPEIHFISESNEQRVPCYRVLDDNGQQLTDSRFVPVSEEVAVKMYSDMVTLQM 429
P G+V P +E+++ RVLDD+G + +S E ++ M+ ++
Sbjct: 31 PAGEVRKPPVDVEPAETSDLAYSLVRVLDDDGHAVGPWN-PQLSNEQLLRGMRAMLKTRL 89
Query: 430 MDNIFYEAQRQGRLSFYATAFGEEAINIASAAALSPQDVIFPQYREPGVLLWRGFTLQEF 609
D AQRQ +LSFY GEEAI A AL D+ FP YR+ G+L+ R + L +
Sbjct: 90 FDARMLTAQRQKKLSFYMQCLGEEAIATAHTLALRDGDMCFPTYRQQGILITREYPLVDM 149
Query: 610 ANQCFGNKSDYGKGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVT 789
Q N++D KGRQ+P+ Y S + +F++S +ATQ AVG + + G A
Sbjct: 150 ICQLLSNEADPLKGRQLPIMYSSKEAGFFSISGNLATQFIQAVGWGMASAIKGDTRIASA 209
Query: 790 FFGDGGSSEGDFHAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVV--KGRAYG 963
+ GDG ++E DFH AL FA V APV+ NN WAIST + +G +G G
Sbjct: 210 WIGDGATAESDFHTALTFAHVYRAPVILNVVNNQWAISTFQAIA-GGEGTTFANRGVGCG 268
Query: 964 IRSIRVDGNDALAMYSAVHEGREMAIREHRPILIEALTYRVGHHSTSDDSTRYRSADEIE 1143
I S+RVDGND LA+Y+A E A R P LIE +TYR G HSTSDD ++YR AD +
Sbjct: 269 IASLRVDGNDFLAVYAASEWAAERARRNLGPSLIEWVTYRAGPHSTSDDPSKYRPAD--D 326
Query: 1144 WWN-KARNPLSRFRTWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEK------TEKPNL 1302
W N +P++R + + G WS+E ++ E+L A + AE P+
Sbjct: 327 WTNFPLGDPIARLKRHMIGLGIWSEEQHEATHKALEAEVLAAQKQAESHGTLIDGRVPSA 386
Query: 1303 NHMFSDVYDVPPLNLREQ 1356
MF DVY P +LR Q
Sbjct: 387 ASMFEDVYAELPEHLRRQ 404
>sp|P37940|ODBA_BACSU 2-oxoisovalerate dehydrogenase subunit alpha OS=Bacillus
subtilis GN=bfmBAA PE=1 SV=1
Length = 330
Score = 203 bits (515), Expect = 4e-051
Identities = 112/304 (36%), Positives = 172/304 (56%), Gaps = 3/304 (0%)
Frame = +1
Query: 376 VSEEVAVKMYSDMVTLQMMDNIFYEAQRQGRLSFYATAFGEEAINIASAAALSPQ-DVIF 552
++++ AV MY M+ + +D + R G++ F + G+EA + +A AL + D +
Sbjct: 11 LTDQEAVDMYRTMLLARKIDERMWLLNRSGKIPFVISCQGQEAAQVGAAFALDREMDYVL 70
Query: 553 PQYREPGVLLWRGFTLQEFANQCFGNKSDYGK-GRQMPVHYGSNKLNYFTVSATIATQLP 729
P YR+ GV+L G T ++ F +D GRQMP H+G K T S+ + TQ+P
Sbjct: 71 PYYRDMGVVLAFGMTAKDLMMSGFAKAADPNSGGRQMPGHFGQKKNRIVTGSSPVTTQVP 130
Query: 730 NAVGAAYSLKMDGKEACAVTFFGDGGSSEGDFHAALNFAAVMEAPVLFICRNNGWAISTP 909
+AVG A + +M+ K+ A FG+G S++GDFH NFAAV + PV+F+C NN +AIS P
Sbjct: 131 HAVGIALAGRMEKKDIAAFVTFGEGSSNQGDFHEGANFAAVHKLPVIFMCENNKYAISVP 190
Query: 910 TSDQFRSDGVVVKGRAYGIRSIRVDGNDALAMYSAVHEGREMAIREHRPILIEALTYRVG 1089
Q + + + YG+ + V+GND L +Y AV E RE A R P LIE ++YR+
Sbjct: 191 YDKQVACENISDRAIGYGMPGVTVNGNDPLEVYQAVKEARERARRGEGPTLIETISYRLT 250
Query: 1090 HHSTSDDSTRYRSADEIEWWNKARNPLSRFRTWVESNGWWSDEAESDLRSRIKKEMLEAI 1269
HS+ DD + YR +E+E K+ +PL ++ +++ G SDE E + I + EA
Sbjct: 251 PHSSDDDDSSYRGREEVEEAKKS-DPLLTYQAYLKETGLLSDEIEQTMLDEIMAIVNEAT 309
Query: 1270 RVAE 1281
AE
Sbjct: 310 DEAE 313
>sp|P09060|ODBA_PSEPU 2-oxoisovalerate dehydrogenase subunit alpha
OS=Pseudomonas putida GN=bkdA1 PE=1 SV=2
Length = 410
Score = 202 bits (512), Expect = 8e-051
Identities = 131/357 (36%), Positives = 187/357 (52%), Gaps = 21/357 (5%)
Frame = +1
Query: 325 RVLDDNGQQLTDSRFVPVSEEVAVKMYSD----MVTLQMMDNIFYEAQRQGRLSFYATAF 492
RVLD+ G P +E++ ++ M+ ++ D+ AQRQ ++SFY +
Sbjct: 56 RVLDEQGDAQG-----PWAEDIDPQILRQGMRAMLKTRIFDSRMVVAQRQKKMSFYMQSL 110
Query: 493 GEEAINIASAAALSPQDVIFPQYREPGVLLWRGFTLQEFANQCFGNKSDYGKGRQMPVHY 672
GEEAI A AL+ D+ FP YR+ +L+ R +L E Q N+ D KGRQ+P+ Y
Sbjct: 111 GEEAIGSGQALALNRTDMCFPTYRQQSILMARDVSLVEMICQLLSNERDPLKGRQLPIMY 170
Query: 673 GSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVTFFGDGGSSEGDFHAALNFAAV 852
+ +FT+S +ATQ AVG A + + G A + GDG ++E DFH AL FA V
Sbjct: 171 SVREAGFFTISGNLATQFVQAVGWAMASAIKGDTKIASAWIGDGATAESDFHTALTFAHV 230
Query: 853 MEAPVLFICRNNGWAIST-PTSDQFRSDGVVVKGRAYGIRSIRVDGNDALAMYSAVHEGR 1029
APV+ NN WAIST S +G GI S+RVDGND +A+Y+A
Sbjct: 231 YRAPVILNVVNNQWAISTFQAIAGGESTTFAGRGVGCGIASLRVDGNDFVAVYAASRWAA 290
Query: 1030 EMAIREHRPILIEALTYRVGHHSTSDDSTRYRSADEIEWWN--KARNPLSRFRTWVESNG 1203
E A R P LIE +TYR G HSTSDD ++YR AD+ W+ +P++R + + G
Sbjct: 291 ERARRGLGPSLIEWVTYRAGPHSTSDDPSKYRPADD---WSHFPLGDPIARLKQHLIKIG 347
Query: 1204 WWSDEAESDLRSRIKKEMLEAIRVAEK------TEKPNLNHMFSDVYDVPPLNLREQ 1356
WS+E + + ++ A + AE+ P+ MF DVY P +LR Q
Sbjct: 348 HWSEEEHQATTAEFEAAVIAAQKEAEQYGTLANGHIPSAASMFEDVYKEMPDHLRRQ 404
>sp|Q5HGZ1|ODPA_STAAC Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus aureus (strain COL) GN=pdhA PE=3 SV=1
Length = 370
Score = 190 bits (481), Expect = 3e-047
Identities = 101/238 (42%), Positives = 145/238 (60%), Gaps = 7/238 (2%)
Frame = +1
Query: 646 KGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVTFFGDGGSSEGDF 825
KG Q P +N + I Q A G A++LK GK A A+T+ GDGGSS+GDF
Sbjct: 129 KGNQFP-----EGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDF 183
Query: 826 HAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGIRSIRVDGNDALAM 1005
+ +NFAA +AP +F+ +NN +AISTP S Q ++ + K A GI I+VDG DALA+
Sbjct: 184 YEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAV 243
Query: 1006 YSAVHEGREMAIREHRPILIEALTYRVGHHS-TSDDSTRYRSADEIEWWNKARNPLSRFR 1182
Y A E R+ A+ P LIE +TYR G H+ DD TRYR++DE W K ++PL RFR
Sbjct: 244 YQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEK-KDPLVRFR 302
Query: 1183 TWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVYDVPPLNLREQ 1356
++E+ G W+++ E+++ R K ++ AI+ A+ TEK + + +Y+ P NL EQ
Sbjct: 303 KFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ 360
>sp|P60089|ODPA_STAAM Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) GN=pdhA PE=1 SV=1
Length = 370
Score = 190 bits (481), Expect = 3e-047
Identities = 101/238 (42%), Positives = 145/238 (60%), Gaps = 7/238 (2%)
Frame = +1
Query: 646 KGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVTFFGDGGSSEGDF 825
KG Q P +N + I Q A G A++LK GK A A+T+ GDGGSS+GDF
Sbjct: 129 KGNQFP-----EGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDF 183
Query: 826 HAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGIRSIRVDGNDALAM 1005
+ +NFAA +AP +F+ +NN +AISTP S Q ++ + K A GI I+VDG DALA+
Sbjct: 184 YEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAV 243
Query: 1006 YSAVHEGREMAIREHRPILIEALTYRVGHHS-TSDDSTRYRSADEIEWWNKARNPLSRFR 1182
Y A E R+ A+ P LIE +TYR G H+ DD TRYR++DE W K ++PL RFR
Sbjct: 244 YQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEK-KDPLVRFR 302
Query: 1183 TWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVYDVPPLNLREQ 1356
++E+ G W+++ E+++ R K ++ AI+ A+ TEK + + +Y+ P NL EQ
Sbjct: 303 KFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ 360
>sp|Q820A6|ODPA_STAAN Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus aureus (strain N315) GN=pdhA PE=1 SV=1
Length = 370
Score = 190 bits (481), Expect = 3e-047
Identities = 101/238 (42%), Positives = 145/238 (60%), Gaps = 7/238 (2%)
Frame = +1
Query: 646 KGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVTFFGDGGSSEGDF 825
KG Q P +N + I Q A G A++LK GK A A+T+ GDGGSS+GDF
Sbjct: 129 KGNQFP-----EGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDF 183
Query: 826 HAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGIRSIRVDGNDALAM 1005
+ +NFAA +AP +F+ +NN +AISTP S Q ++ + K A GI I+VDG DALA+
Sbjct: 184 YEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAV 243
Query: 1006 YSAVHEGREMAIREHRPILIEALTYRVGHHS-TSDDSTRYRSADEIEWWNKARNPLSRFR 1182
Y A E R+ A+ P LIE +TYR G H+ DD TRYR++DE W K ++PL RFR
Sbjct: 244 YQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEK-KDPLVRFR 302
Query: 1183 TWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVYDVPPLNLREQ 1356
++E+ G W+++ E+++ R K ++ AI+ A+ TEK + + +Y+ P NL EQ
Sbjct: 303 KFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ 360
>sp|Q6GAC1|ODPA_STAAS Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus aureus (strain MSSA476) GN=pdhA PE=3 SV=1
Length = 370
Score = 190 bits (481), Expect = 3e-047
Identities = 101/238 (42%), Positives = 145/238 (60%), Gaps = 7/238 (2%)
Frame = +1
Query: 646 KGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVTFFGDGGSSEGDF 825
KG Q P +N + I Q A G A++LK GK A A+T+ GDGGSS+GDF
Sbjct: 129 KGNQFP-----EGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDF 183
Query: 826 HAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGIRSIRVDGNDALAM 1005
+ +NFAA +AP +F+ +NN +AISTP S Q ++ + K A GI I+VDG DALA+
Sbjct: 184 YEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAV 243
Query: 1006 YSAVHEGREMAIREHRPILIEALTYRVGHHS-TSDDSTRYRSADEIEWWNKARNPLSRFR 1182
Y A E R+ A+ P LIE +TYR G H+ DD TRYR++DE W K ++PL RFR
Sbjct: 244 YQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEK-KDPLVRFR 302
Query: 1183 TWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVYDVPPLNLREQ 1356
++E+ G W+++ E+++ R K ++ AI+ A+ TEK + + +Y+ P NL EQ
Sbjct: 303 KFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ 360
>sp|P60090|ODPA_STAAW Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus aureus (strain MW2) GN=pdhA PE=3 SV=1
Length = 370
Score = 190 bits (481), Expect = 3e-047
Identities = 101/238 (42%), Positives = 145/238 (60%), Gaps = 7/238 (2%)
Frame = +1
Query: 646 KGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVTFFGDGGSSEGDF 825
KG Q P +N + I Q A G A++LK GK A A+T+ GDGGSS+GDF
Sbjct: 129 KGNQFP-----EGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDF 183
Query: 826 HAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGIRSIRVDGNDALAM 1005
+ +NFAA +AP +F+ +NN +AISTP S Q ++ + K A GI I+VDG DALA+
Sbjct: 184 YEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAV 243
Query: 1006 YSAVHEGREMAIREHRPILIEALTYRVGHHS-TSDDSTRYRSADEIEWWNKARNPLSRFR 1182
Y A E R+ A+ P LIE +TYR G H+ DD TRYR++DE W K ++PL RFR
Sbjct: 244 YQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEK-KDPLVRFR 302
Query: 1183 TWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVYDVPPLNLREQ 1356
++E+ G W+++ E+++ R K ++ AI+ A+ TEK + + +Y+ P NL EQ
Sbjct: 303 KFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ 360
>sp|Q6GHZ2|ODPA_STAAR Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus aureus (strain MRSA252) GN=pdhA PE=3 SV=1
Length = 370
Score = 188 bits (477), Expect = 1e-046
Identities = 100/238 (42%), Positives = 144/238 (60%), Gaps = 7/238 (2%)
Frame = +1
Query: 646 KGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVTFFGDGGSSEGDF 825
KG Q P +N + I Q G A++LK GK A A+T+ GDGGSS+GDF
Sbjct: 129 KGNQFP-----EGVNALSPQIIIGAQYIQTAGVAFALKKRGKNAVAITYTGDGGSSQGDF 183
Query: 826 HAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGIRSIRVDGNDALAM 1005
+ +NFAA +AP +F+ +NN +AISTP S Q ++ + K A GI I+VDG DALA+
Sbjct: 184 YEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAV 243
Query: 1006 YSAVHEGREMAIREHRPILIEALTYRVGHHS-TSDDSTRYRSADEIEWWNKARNPLSRFR 1182
Y A E R+ A+ P LIE +TYR G H+ DD TRYR++DE W K ++PL RFR
Sbjct: 244 YQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEK-KDPLVRFR 302
Query: 1183 TWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVYDVPPLNLREQ 1356
++E+ G W+++ E+++ R K ++ AI+ A+ TEK + + +Y+ P NL EQ
Sbjct: 303 KFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ 360
>sp|Q5HQ76|ODPA_STAEQ Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) GN=pdhA PE=3
SV=1
Length = 370
Score = 188 bits (476), Expect = 1e-046
Identities = 100/238 (42%), Positives = 143/238 (60%), Gaps = 7/238 (2%)
Frame = +1
Query: 646 KGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVTFFGDGGSSEGDF 825
KG Q P +N + I Q G A+ LK GK A A+T+ GDGGSS+GDF
Sbjct: 129 KGNQFP-----EGVNALSPQIIIGAQYIQTAGVAFGLKKRGKNAVAITYTGDGGSSQGDF 183
Query: 826 HAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGIRSIRVDGNDALAM 1005
+ +NFA+ +AP +F+ +NN +AISTP S Q ++ + K + GI I+VDG DALA+
Sbjct: 184 YEGINFASAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAISVGIPGIQVDGMDALAV 243
Query: 1006 YSAVHEGREMAIREHRPILIEALTYRVGHHS-TSDDSTRYRSADEIEWWNKARNPLSRFR 1182
Y A E RE A+ P +IE LTYR G H+ DD TRYR++DE W K ++PL RFR
Sbjct: 244 YQATLEARERAVAGEGPTVIETLTYRYGPHTMAGDDPTRYRTSDEDAEWEK-KDPLVRFR 302
Query: 1183 TWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVYDVPPLNLREQ 1356
++E+ G W+++ E+++ R K E+ AI+ A+ TEK + + +Y+ P NL EQ
Sbjct: 303 KYLEAKGLWNEDKENEVVERAKSEIKAAIKEADNTEKQTVTSLMDIMYEEMPQNLAEQ 360
>sp|Q8CPN3|ODPA_STAES Pyruvate dehydrogenase E1 component subunit alpha
OS=Staphylococcus epidermidis (strain ATCC 12228) GN=pdhA PE=3 SV=1
Length = 370
Score = 188 bits (476), Expect = 1e-046
Identities = 100/238 (42%), Positives = 143/238 (60%), Gaps = 7/238 (2%)
Frame = +1
Query: 646 KGRQMPVHYGSNKLNYFTVSATIATQLPNAVGAAYSLKMDGKEACAVTFFGDGGSSEGDF 825
KG Q P +N + I Q G A+ LK GK A A+T+ GDGGSS+GDF
Sbjct: 129 KGNQFP-----EGVNALSPQIIIGAQYIQTAGVAFGLKKRGKNAVAITYTGDGGSSQGDF 183
Query: 826 HAALNFAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVKGRAYGIRSIRVDGNDALAM 1005
+ +NFA+ +AP +F+ +NN +AISTP S Q ++ + K + GI I+VDG DALA+
Sbjct: 184 YEGINFASAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAISVGIPGIQVDGMDALAV 243
Query: 1006 YSAVHEGREMAIREHRPILIEALTYRVGHHS-TSDDSTRYRSADEIEWWNKARNPLSRFR 1182
Y A E RE A+ P +IE LTYR G H+ DD TRYR++DE W K ++PL RFR
Sbjct: 244 YQATLEARERAVAGEGPTVIETLTYRYGPHTMAGDDPTRYRTSDEDAEWEK-KDPLVRFR 302
Query: 1183 TWVESNGWWSDEAESDLRSRIKKEMLEAIRVAEKTEKPNLNHMFSDVYDVPPLNLREQ 1356
++E+ G W+++ E+++ R K E+ AI+ A+ TEK + + +Y+ P NL EQ
Sbjct: 303 KYLEAKGLWNEDKENEVVERAKSEIKAAIKEADNTEKQTVTSLMDIMYEEMPQNLAEQ 360
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,727,594,170
Number of Sequences: 518415
Number of Extensions: 61727594170
Number of Successful Extensions: 397900902
Number of sequences better than 0.0: 0
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