BLASTX 7.6.2
Query= UN15077 /QuerySize=912
(911 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q12296|MAM3_YEAST Protein MAM3 OS=Saccharomyces cerevisiae GN... 141 6e-033
sp|Q9USJ3|YJ23_SCHPO Uncharacterized protein C4B3.03c OS=Schizos... 137 2e-031
sp|Q69ZF7|CNNM4_MOUSE Metal transporter CNNM4 OS=Mus musculus GN... 125 5e-028
sp|P0C588|CNNM4_RAT Metal transporter CNNM4 OS=Rattus norvegicus... 125 6e-028
sp|Q6P4Q7|CNNM4_HUMAN Metal transporter CNNM4 OS=Homo sapiens GN... 124 1e-027
sp|A0JPA0|CNNM4_XENTR Metal transporter CNNM4 OS=Xenopus tropica... 123 2e-027
sp|Q9H8M5|CNNM2_HUMAN Metal transporter CNNM2 OS=Homo sapiens GN... 119 3e-026
sp|Q3TWN3|CNNM2_MOUSE Metal transporter CNNM2 OS=Mus musculus GN... 119 3e-026
sp|Q5U2P1|CNNM2_RAT Metal transporter CNNM2 OS=Rattus norvegicus... 119 3e-026
sp|Q8NE01|CNNM3_HUMAN Metal transporter CNNM3 OS=Homo sapiens GN... 65 8e-010
sp|Q32NY4|CNNM3_MOUSE Metal transporter CNNM3 OS=Mus musculus GN... 62 4e-009
sp|P74078|Y1254_SYNY3 UPF0053 protein sll1254 OS=Synechocystis s... 56 4e-007
sp|Q9NRU3|CNNM1_HUMAN Metal transporter CNNM1 OS=Homo sapiens GN... 53 3e-006
sp|Q0GA42|CNNM1_MOUSE Metal transporter CNNM1 OS=Mus musculus GN... 53 3e-006
>sp|Q12296|MAM3_YEAST Protein MAM3 OS=Saccharomyces cerevisiae GN=MAM3 PE=1
SV=1
Length = 706
Score = 141 bits (355), Expect = 6e-033
Identities = 74/171 (43%), Positives = 113/171 (66%), Gaps = 2/171 (1%)
Frame = +2
Query: 326 EANFFIHIAVIAFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTPQHRQYAEKILPVV-K 502
EA+ + + LVL G+ +GLTLGLM V L+V++ SG+ ++ A+++L ++ +
Sbjct: 58 EASVTTYYIISIILVLLGGVFAGLTLGLMGQDEVYLKVISTSGSNSEKKLAKRVLDLISR 117
Query: 503 NQHLLLVTLLVCNAAAMETLPIFLD-SLVTAWGAILISVTLILLFGEIIPQSICSRYGLA 679
+H +LVTLL+ N ETLPI LD L W A++ S LI++FGEIIPQS+C +YGL
Sbjct: 118 GKHWVLVTLLLSNVITNETLPIVLDRCLGGGWQAVVSSTILIVIFGEIIPQSVCVKYGLQ 177
Query: 680 IGATVASFVRVLVFVCLPVAWPISKLLDFLLGHRRAALFRRAELKTLVDFH 832
+GA FV VL+++ PVA+PI+ LLD++LG +++++ LKTLV H
Sbjct: 178 VGAFFCPFVLVLMYLMYPVAYPIATLLDYMLGEDHGTMYKKSGLKTLVTLH 228
>sp|Q9USJ3|YJ23_SCHPO Uncharacterized protein C4B3.03c OS=Schizosaccharomyces
pombe GN=SPCC4B3.03c PE=1 SV=1
Length = 679
Score = 137 bits (343), Expect = 2e-031
Identities = 70/182 (38%), Positives = 119/182 (65%), Gaps = 3/182 (1%)
Frame = +2
Query: 293 GVLMAAELECCEANFFIHIAVIAFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTPQHRQ 472
G ++AE + + +++ + + A L+L G+ +GLT+GLM + L+VL +SG R
Sbjct: 49 GGFVSAEKD-SDFEYWMKLIISAVLILLGGVFAGLTIGLMGCDDLHLQVLEQSGDASERV 107
Query: 473 YAEKILPVV-KNQHLLLVTLLVCNAAAMETLPIFLDSLV-TAWGAILISVTLILLFGEII 646
+A K+L ++ + +H +LVTLL+ N ETLPI DS++ W A+LIS +I++FGE+I
Sbjct: 108 HARKVLKLLRRGKHWVLVTLLLGNVIVNETLPIVFDSIIGGGWPAVLISTAMIVIFGEVI 167
Query: 647 PQSICSRYGLAIGATVASFVRVLVFVCLPVAWPISKLLDFLLGHRRAALFRRAELKTLVD 826
PQ+ C RYGL+IGA + V ++++ P+A+P + +LD LG ++ +++++ LKTLV
Sbjct: 168 PQATCVRYGLSIGAKLEPIVLFMMYLLWPIAYPTALILDACLGESQSTMYKKSGLKTLVT 227
Query: 827 FH 832
H
Sbjct: 228 LH 229
>sp|Q69ZF7|CNNM4_MOUSE Metal transporter CNNM4 OS=Mus musculus GN=Cnnm4 PE=1
SV=2
Length = 771
Score = 125 bits (313), Expect = 5e-028
Identities = 62/163 (38%), Positives = 107/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 338 FIHIAVIAFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTPQHRQYAEKILPVVKNQHLL 517
++HI ++ L++ +G+ SGL LGLM+L ++L ++ GT + R+YA KI P+ + + L
Sbjct: 180 WLHILLVMVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERKYARKIEPIRRKGNYL 239
Query: 518 LVTLLVCNAAAMETLPIFLDSLVTAWGAILISVTL-ILLFGEIIPQSICSRYGLAIGATV 694
L +LL+ N +L I LD+L+ + + S T+ I++FGEI+PQ++CSR+GLA+GA
Sbjct: 240 LCSLLLGNVLVNTSLTILLDNLIGSGIMAVASSTIGIVIFGEILPQALCSRHGLAVGANT 299
Query: 695 ASFVRVLVFVCLPVAWPISKLLDFLLGHRRAALFRRAELKTLV 823
+V + + P+++PISKLLDF+LG ++ R +L ++
Sbjct: 300 IVLTKVFMLLTFPLSFPISKLLDFVLGQEIRTVYNREKLMEML 342
>sp|P0C588|CNNM4_RAT Metal transporter CNNM4 OS=Rattus norvegicus GN=Cnnm4 PE=1
SV=1
Length = 772
Score = 125 bits (312), Expect = 6e-028
Identities = 61/163 (37%), Positives = 107/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 338 FIHIAVIAFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTPQHRQYAEKILPVVKNQHLL 517
++HI ++ L++ +G+ SGL LGLM+L ++L ++ GT + R+YA KI P+ + + L
Sbjct: 181 WLHILLVLVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERRYARKIEPIRRKGNYL 240
Query: 518 LVTLLVCNAAAMETLPIFLDSLVTAWGAILISVTL-ILLFGEIIPQSICSRYGLAIGATV 694
L +LL+ N +L I LD+L+ + + S T+ I++FGEI+PQ++CSR+GLA+GA
Sbjct: 241 LCSLLLGNVLVNTSLTILLDNLIGSGIMAVASSTIGIVIFGEILPQALCSRHGLAVGANT 300
Query: 695 ASFVRVLVFVCLPVAWPISKLLDFLLGHRRAALFRRAELKTLV 823
++ + + P+++PISKLLDF+LG ++ R +L ++
Sbjct: 301 IVLTKIFMLLTFPLSFPISKLLDFVLGQEIRTVYNREKLMEML 343
>sp|Q6P4Q7|CNNM4_HUMAN Metal transporter CNNM4 OS=Homo sapiens GN=CNNM4 PE=1
SV=3
Length = 775
Score = 124 bits (309), Expect = 1e-027
Identities = 62/163 (38%), Positives = 105/163 (64%), Gaps = 1/163 (0%)
Frame = +2
Query: 338 FIHIAVIAFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTPQHRQYAEKILPVVKNQHLL 517
++HI +I L++ +G+ SGL LGLM+L ++L ++ GT + R+YA KI P+ + + L
Sbjct: 183 WLHILLITVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERRYARKIEPIRRKGNYL 242
Query: 518 LVTLLVCNAAAMETLPIFLDSLVTAWGAILISVTL-ILLFGEIIPQSICSRYGLAIGATV 694
L +LL+ N +L I LD+L+ + + S T+ I++FGEI+PQ++CSR+GLA+GA
Sbjct: 243 LCSLLLGNVLVNTSLTILLDNLIGSGLMAVASSTIGIVIFGEILPQALCSRHGLAVGANT 302
Query: 695 ASFVRVLVFVCLPVAWPISKLLDFLLGHRRAALFRRAELKTLV 823
+ + + P+++PISKLLDF LG ++ R +L ++
Sbjct: 303 ILLTKFFMLLTFPLSFPISKLLDFFLGQEIRTVYNREKLMEML 345
>sp|A0JPA0|CNNM4_XENTR Metal transporter CNNM4 OS=Xenopus tropicalis GN=cnnm4
PE=2 SV=1
Length = 769
Score = 123 bits (308), Expect = 2e-027
Identities = 63/159 (39%), Positives = 100/159 (62%), Gaps = 1/159 (0%)
Frame = +2
Query: 338 FIHIAVIAFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTPQHRQYAEKILPVVKNQHLL 517
++ +IA L+ +G+ SGL LGLM+L ++L V+ + GT + ++YA KI PV + + L
Sbjct: 180 WLQACIIAVLLTLSGIFSGLNLGLMALDPMELRVVQRCGTEKEKRYASKIEPVRRKGNYL 239
Query: 518 LVTLLVCNAAAMETLPIFLDSLV-TAWGAILISVTLILLFGEIIPQSICSRYGLAIGATV 694
L +LL+ N TL LD L+ + A+L S T I++ GEI+PQ++CSR+GLA+GA
Sbjct: 240 LCSLLLGNVLVNTTLTALLDELIGSGLAAVLASTTGIVVLGEIVPQALCSRHGLAVGANT 299
Query: 695 ASFVRVLVFVCLPVAWPISKLLDFLLGHRRAALFRRAEL 811
R+ + + PVA+P+S+LLD LG ++ R +L
Sbjct: 300 LWLTRIFMLLTFPVAYPVSRLLDCALGQEIGTVYNREKL 338
>sp|Q9H8M5|CNNM2_HUMAN Metal transporter CNNM2 OS=Homo sapiens GN=CNNM2 PE=2
SV=2
Length = 875
Score = 119 bits (298), Expect = 3e-026
Identities = 59/160 (36%), Positives = 100/160 (62%), Gaps = 1/160 (0%)
Frame = +2
Query: 335 FFIHIAVIAFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTPQHRQYAEKILPVVKNQHL 514
F++ + I+ L+ +G+ SGL LGLM+L ++L ++ GT + + YA++I PV + +
Sbjct: 255 FWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNY 314
Query: 515 LLVTLLVCNAAAMETLPIFLDSLV-TAWGAILISVTLILLFGEIIPQSICSRYGLAIGAT 691
LL +LL+ N TL I LD + + A+++S I++FGEI+PQ+ICSR+GLA+GA
Sbjct: 315 LLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGAN 374
Query: 692 VASFVRVLVFVCLPVAWPISKLLDFLLGHRRAALFRRAEL 811
+ + + P ++P+SKLLD +LG ++ R +L
Sbjct: 375 TIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKL 414
>sp|Q3TWN3|CNNM2_MOUSE Metal transporter CNNM2 OS=Mus musculus GN=Cnnm2 PE=1
SV=2
Length = 875
Score = 119 bits (298), Expect = 3e-026
Identities = 59/160 (36%), Positives = 100/160 (62%), Gaps = 1/160 (0%)
Frame = +2
Query: 335 FFIHIAVIAFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTPQHRQYAEKILPVVKNQHL 514
F++ + I+ L+ +G+ SGL LGLM+L ++L ++ GT + + YA++I PV + +
Sbjct: 255 FWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNY 314
Query: 515 LLVTLLVCNAAAMETLPIFLDSLV-TAWGAILISVTLILLFGEIIPQSICSRYGLAIGAT 691
LL +LL+ N TL I LD + + A+++S I++FGEI+PQ+ICSR+GLA+GA
Sbjct: 315 LLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGAN 374
Query: 692 VASFVRVLVFVCLPVAWPISKLLDFLLGHRRAALFRRAEL 811
+ + + P ++P+SKLLD +LG ++ R +L
Sbjct: 375 TIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKL 414
>sp|Q5U2P1|CNNM2_RAT Metal transporter CNNM2 OS=Rattus norvegicus GN=Cnnm2 PE=2
SV=1
Length = 875
Score = 119 bits (298), Expect = 3e-026
Identities = 59/160 (36%), Positives = 100/160 (62%), Gaps = 1/160 (0%)
Frame = +2
Query: 335 FFIHIAVIAFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTPQHRQYAEKILPVVKNQHL 514
F++ + I+ L+ +G+ SGL LGLM+L ++L ++ GT + + YA++I PV + +
Sbjct: 255 FWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNY 314
Query: 515 LLVTLLVCNAAAMETLPIFLDSLV-TAWGAILISVTLILLFGEIIPQSICSRYGLAIGAT 691
LL +LL+ N TL I LD + + A+++S I++FGEI+PQ+ICSR+GLA+GA
Sbjct: 315 LLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGAN 374
Query: 692 VASFVRVLVFVCLPVAWPISKLLDFLLGHRRAALFRRAEL 811
+ + + P ++P+SKLLD +LG ++ R +L
Sbjct: 375 TIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKL 414
>sp|Q8NE01|CNNM3_HUMAN Metal transporter CNNM3 OS=Homo sapiens GN=CNNM3 PE=1
SV=1
Length = 707
Score = 65 bits (156), Expect = 8e-010
Identities = 42/137 (30%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
Frame = +2
Query: 359 AFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTPQHRQYAEKILPVVKNQHLLLVTLLVC 538
A L+ A L GL L ++L+ +++VL +SG+ R A ++ P + L LL+
Sbjct: 142 AGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPARRWAGCALGALLLL 201
Query: 539 NAAAMETLPIFLDSLV--TAWGAILISVTLILLFGEIIPQSICSRYGLAIGATVASFVRV 712
+ A L + L A A+L S L+ L GE++P ++ R+ LA+ R+
Sbjct: 202 ASLAQAALAVLLYRAAGQRAVPAVLGSAGLVFLVGEVVPAAVSGRWTLALAPRALGLSRL 261
Query: 713 LVFVCLPVAWPISKLLD 763
V + LPVA P+ +LL+
Sbjct: 262 AVLLTLPVALPVGQLLE 278
>sp|Q32NY4|CNNM3_MOUSE Metal transporter CNNM3 OS=Mus musculus GN=Cnnm3 PE=1
SV=2
Length = 713
Score = 62 bits (150), Expect = 4e-009
Identities = 40/137 (29%), Positives = 69/137 (50%), Gaps = 2/137 (1%)
Frame = +2
Query: 359 AFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTPQHRQYAEKILPVVKNQHLLLVTLLVC 538
A L+ A + GL L ++L+ +++VL +SG+ R A ++ P + L LL+
Sbjct: 148 AGLLALAAVARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPARRWAGCALGALLLL 207
Query: 539 NAAAMETLPIFLDSLV--TAWGAILISVTLILLFGEIIPQSICSRYGLAIGATVASFVRV 712
+ A L + L A A+L L+ L GE++P ++ R+ LA+ R+
Sbjct: 208 ASLAQAALAVLLYGAAGQRAVPAVLGCAGLVFLVGEVLPAAVSGRWALALAPRALGLSRL 267
Query: 713 LVFVCLPVAWPISKLLD 763
V + LPVA P+ +LL+
Sbjct: 268 AVLLTLPVALPVGQLLE 284
>sp|P74078|Y1254_SYNY3 UPF0053 protein sll1254 OS=Synechocystis sp. (strain PCC
6803) GN=sll1254 PE=3 SV=1
Length = 346
Score = 56 bits (133), Expect = 4e-007
Identities = 47/166 (28%), Positives = 76/166 (45%), Gaps = 13/166 (7%)
Frame = +2
Query: 347 IAVIAFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTP--------QHRQYAEKILPVVK 502
+A I ++L +G+ S L S+ LV + L++S P +HR VV
Sbjct: 5 VAAIFIVLLGSGICSCAEAALFSVPLVKVRQLSQSNNPSAIALQAIRHRMNRPIGTIVVL 64
Query: 503 NQHLLLVTLLVCNAAAMETLPIFLDSLVTAWGAILISVTLILLFGEIIPQSICSRYGLAI 682
N +V + A A + L D+ + + IL LI++FGEIIP+++ RY I
Sbjct: 65 NNIFNIVGSITIGALATKHLQ---DAWMGVFSGIL--TLLIIVFGEIIPKTLGERYATNI 119
Query: 683 GATVASFVRVLVFVCLPVAWPISKLLDFLLGHRRAALFRRAELKTL 820
+A VR L + P+ W I ++ + +R AE+K L
Sbjct: 120 ALLIAIPVRFLTLIFTPLVWLIEQITNPFTHGKRVPSTNEAEIKFL 165
>sp|Q9NRU3|CNNM1_HUMAN Metal transporter CNNM1 OS=Homo sapiens GN=CNNM1 PE=2
SV=2
Length = 880
Score = 53 bits (125), Expect = 3e-006
Identities = 25/73 (34%), Positives = 39/73 (53%)
Frame = +2
Query: 593 WGAILISVTLILLFGEIIPQSICSRYGLAIGATVASFVRVLVFVCLPVAWPISKLLDFLL 772
W L+ + L EI P S+CSR+GLAI + R+L+ PV +P+ +LLD+ L
Sbjct: 254 WLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWAL 313
Query: 773 GHRRAALFRRAEL 811
+ + R +L
Sbjct: 314 RQEISTFYTREKL 326
>sp|Q0GA42|CNNM1_MOUSE Metal transporter CNNM1 OS=Mus musculus GN=Cnnm1 PE=1
SV=4
Length = 880
Score = 53 bits (125), Expect = 3e-006
Identities = 25/73 (34%), Positives = 39/73 (53%)
Frame = +2
Query: 593 WGAILISVTLILLFGEIIPQSICSRYGLAIGATVASFVRVLVFVCLPVAWPISKLLDFLL 772
W L+ + L EI P S+CSR+GLAI + R+L+ PV +P+ +LLD+ L
Sbjct: 254 WLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWAL 313
Query: 773 GHRRAALFRRAEL 811
+ + R +L
Sbjct: 314 PQEISTFYTREKL 326
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,727,594,170
Number of Sequences: 518415
Number of Extensions: 61727594170
Number of Successful Extensions: 397900902
Number of sequences better than 0.0: 0
|
