BLASTX 7.6.2
Query= UN15387 /QuerySize=1617
(1616 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q17QF2|N6MT2_BOVIN N(6)-adenine-specific DNA methyltransferas... 183 5e-045
sp|Q8WVE0|N6MT2_HUMAN N(6)-adenine-specific DNA methyltransferas... 181 2e-044
sp|Q9CY45|N6MT2_MOUSE N(6)-adenine-specific DNA methyltransferas... 178 2e-043
sp|Q5ZKT6|N6MT2_CHICK N(6)-adenine-specific DNA methyltransferas... 174 3e-042
sp|Q6GN98|N6MT2_XENLA N(6)-adenine-specific DNA methyltransferas... 166 4e-040
sp|Q6NYP8|N6MT2_DANRE N(6)-adenine-specific DNA methyltransferas... 138 1e-031
sp|Q5WRN3|N6MT2_CAEEL N(6)-adenine-specific DNA methyltransferas... 129 9e-029
sp|Q86A24|N6MT2_DICDI N(6)-adenine-specific DNA methyltransferas... 126 8e-028
sp|P53200|AML1_YEAST N(6)-adenine-specific DNA methyltransferase... 85 2e-015
>sp|Q17QF2|N6MT2_BOVIN N(6)-adenine-specific DNA methyltransferase 2 OS=Bos
taurus GN=N6AMT2 PE=2 SV=1
Length = 226
Score = 183 bits (462), Expect = 5e-045
Identities = 98/217 (45%), Positives = 138/217 (63%), Gaps = 15/217 (6%)
Frame = +3
Query: 126 EDDDPLVLSSQALAALQEFLADQNKTVTVTPPPSTVDGGDK--VELVTEDWRLSQFWYEP 299
E++ P LSS ALAALQEF A+Q S + G DK + ++ E+W+LSQFWY P
Sbjct: 5 ENEGPPQLSSYALAALQEFYAEQQH------HHSDLCGDDKYNIGIIEENWQLSQFWYSP 58
Query: 300 ETAETVAEEVVTLSNRFSGCRVACIACPTLYVYLKKKD-PSLQVQLLEYDMRFERYGSEF 476
ETA +AE+ V + G R+AC++ P++Y L+++ + V + EYD RF YG +F
Sbjct: 59 ETATCLAEDAVAAAG--EGGRIACVSAPSVYQKLRERHRDDVSVCIFEYDRRFAIYGEDF 116
Query: 477 TFYDYNEPEDLPPQL-KHCFHIIVADPPYLSKECLERVTQTVSFLASPVDSLLLLLTGDV 653
+YDY P DLP ++ H F I+VADPPYLS+ECL ++++T+ L +LL TG V
Sbjct: 117 VYYDYKNPVDLPERIATHSFDIVVADPPYLSEECLRKMSETIKLLTR---GKILLCTGAV 173
Query: 654 QRDRAAELLGVRPCVFKPHHSSKLGNEFRLFISYDPG 764
D AA+LLGV+ C F P H+ LGNEFR F++Y+ G
Sbjct: 174 MEDAAAKLLGVKMCKFIPEHTRTLGNEFRCFVNYNSG 210
>sp|Q8WVE0|N6MT2_HUMAN N(6)-adenine-specific DNA methyltransferase 2 OS=Homo
sapiens GN=N6AMT2 PE=1 SV=1
Length = 214
Score = 181 bits (457), Expect = 2e-044
Identities = 93/218 (42%), Positives = 134/218 (61%), Gaps = 12/218 (5%)
Frame = +3
Query: 129 DDDPLVLSSQALAALQEFLADQNKTVTVTPPPSTVDGGDKVELVTEDWRLSQFWYEPETA 308
DD+ LS+ ALAALQEF A+Q + + D + ++ E+W+LSQFWY ETA
Sbjct: 6 DDETPQLSAHALAALQEFYAEQKQQI-----EPGEDDKYNIGIIEENWQLSQFWYSQETA 60
Query: 309 ETVAEEVVTLSNRFSGCRVACIACPTLYVYLKKK-DPSLQVQLLEYDMRFERYGSEFTFY 485
+A+E + G R+AC++ P++Y L++ + + + EYD RF YG EF FY
Sbjct: 61 LQLAQEAIAAVG--EGGRIACVSAPSVYQKLRELCRENFSIYIFEYDKRFAMYGEEFIFY 118
Query: 486 DYNEPEDLPPQL-KHCFHIIVADPPYLSKECLERVTQTVSFLASPVDSLLLLLTGDVQRD 662
DYN P DLP ++ H F I++ADPPYLS+ECL + ++TV +L +LL TG + +
Sbjct: 119 DYNNPLDLPERIAAHSFDIVIADPPYLSEECLRKTSETVKYLTR---GKILLCTGAIMEE 175
Query: 663 RAAELLGVRPCVFKPHHSSKLGNEFRLFISYDPGTRLG 776
+AAELLGV+ C F P H+ L NEFR +++YD G G
Sbjct: 176 QAAELLGVKMCTFVPRHTRNLANEFRCYVNYDSGLDCG 213
>sp|Q9CY45|N6MT2_MOUSE N(6)-adenine-specific DNA methyltransferase 2 OS=Mus
musculus GN=N6amt2 PE=2 SV=1
Length = 214
Score = 178 bits (449), Expect = 2e-043
Identities = 98/218 (44%), Positives = 136/218 (62%), Gaps = 20/218 (9%)
Frame = +3
Query: 129 DDDPLVLSSQALAALQEFLADQNKTVTVTPPPSTVDGGDK--VELVTEDWRLSQFWYEPE 302
DDD LSS LAALQEF A+Q ++V G DK V ++ E+W+LSQFWY +
Sbjct: 6 DDDIPQLSSHTLAALQEFYAEQKQSVNPR-------GDDKYNVGVIEENWQLSQFWYSQD 58
Query: 303 TAETVAEEVVTLSNRFSGCRVACIACPTLYVYLK---KKDPSLQVQLLEYDMRFERYGSE 473
TA +A E + + G R+AC++ P++Y L+ ++D S V + EYD RF YG E
Sbjct: 59 TALRLAREAIDAAG--EGGRIACVSAPSVYQKLRELCREDSS--VYIFEYDRRFAIYGDE 114
Query: 474 FTFYDYNEPEDLPPQL-KHCFHIIVADPPYLSKECLERVTQTVSFLASPVDSLLLLLTGD 650
F FYDYN P +LP ++ H F ++VADPPYLS+ECL + ++T+ FL +LL TG
Sbjct: 115 FIFYDYNHPLELPERIAAHSFDLVVADPPYLSEECLRKTSETIQFLTR---GKILLCTGA 171
Query: 651 VQRDRAAELLGVRPCVFKPHHSSKLGNEFRLFISYDPG 764
+ ++AA+LLGV+ C F P HS L NEFR + +YD G
Sbjct: 172 IMEEQAAQLLGVKMCKFIPEHSRNLANEFRCYTNYDSG 209
>sp|Q5ZKT6|N6MT2_CHICK N(6)-adenine-specific DNA methyltransferase 2 OS=Gallus
gallus GN=N6AMT2 PE=2 SV=1
Length = 213
Score = 174 bits (439), Expect = 3e-042
Identities = 95/217 (43%), Positives = 133/217 (61%), Gaps = 13/217 (5%)
Frame = +3
Query: 126 EDDDPLVLSSQALAALQEFLADQNKTVTVTPPPSTVDGGDK--VELVTEDWRLSQFWYEP 299
+DDD LSS LAALQEF +Q + + T G ++ V + EDW+LSQFWY
Sbjct: 4 DDDDIPQLSSHTLAALQEFYLEQQQREGM----KTSQGFNQYSVGSIEEDWQLSQFWYSD 59
Query: 300 ETAETVAEEVVTLSNRFSGCRVACIACPTLYVYLKKK-DPSLQVQLLEYDMRFERYGSEF 476
ETA +A E + + + G R+AC++ P++Y L+++ V +LEYD RF YG EF
Sbjct: 60 ETASCLANEAIVAAGK--GGRIACVSAPSVYQKLREQGGADFSVCILEYDRRFSVYGEEF 117
Query: 477 TFYDYNEPEDLPPQ-LKHCFHIIVADPPYLSKECLERVTQTVSFLASPVDSLLLLLTGDV 653
FYDYN P +LP L H F I+VADPPYLS+ECL++ +T+ +L +LL TG +
Sbjct: 118 IFYDYNNPLNLPEHLLPHSFDIVVADPPYLSEECLQKTAETIKYLTK---GKILLCTGAI 174
Query: 654 QRDRAAELLGVRPCVFKPHHSSKLGNEFRLFISYDPG 764
++AA+ LGV+ C F P HS L NEFR +++Y G
Sbjct: 175 MEEQAAKHLGVKICKFIPKHSRNLANEFRCYVNYASG 211
>sp|Q6GN98|N6MT2_XENLA N(6)-adenine-specific DNA methyltransferase 2 OS=Xenopus
laevis GN=n6amt2 PE=2 SV=1
Length = 220
Score = 166 bits (420), Expect = 4e-040
Identities = 94/213 (44%), Positives = 128/213 (60%), Gaps = 9/213 (4%)
Frame = +3
Query: 126 EDDDPLVLSSQALAALQEFLADQNKTVTVTPPPSTVDGGDKVELVTEDWRLSQFWYEPET 305
+DD LSS ALAALQEF A+Q + P V V EDW+LSQFWY ET
Sbjct: 6 DDDGVPQLSSHALAALQEFYAEQQQREAQKLGPD--HEKFSVGSVEEDWQLSQFWYSDET 63
Query: 306 AETVAEEVVTLSNRFSGCRVACIACPTLYVYLK-KKDPSLQVQLLEYDMRFERYGSEFTF 482
A ++A+E + + R+ACI+ P++Y L+ S+ ++LLEYD RF YG +F F
Sbjct: 64 ALSLAKEAIEVCG--ENGRIACISAPSIYQKLRGLAGESVYIRLLEYDNRFAVYGDDFVF 121
Query: 483 YDYNEPEDLPPQLK-HCFHIIVADPPYLSKECLERVTQTVSFLASPVDSLLLLLTGDVQR 659
YDYNEP LP L+ F I++ADPPYLS+ECL+ QT+ L+ ++L TG V
Sbjct: 122 YDYNEPLKLPESLEPSSFDIVIADPPYLSEECLQNTAQTIKHLSR---GKIILCTGAVME 178
Query: 660 DRAAELLGVRPCVFKPHHSSKLGNEFRLFISYD 758
D AA+ LG++ C F P H+ L NEFR + +Y+
Sbjct: 179 DLAAQKLGLKKCKFIPEHTRNLANEFRCYSNYE 211
>sp|Q6NYP8|N6MT2_DANRE N(6)-adenine-specific DNA methyltransferase 2 OS=Danio
rerio GN=n6amt2 PE=2 SV=1
Length = 166
Score = 138 bits (347), Expect = 1e-031
Identities = 71/166 (42%), Positives = 100/166 (60%), Gaps = 10/166 (6%)
Frame = +3
Query: 276 LSQFWYEPETAETVAEEVVTLSNRFSGCRVACIACPTLYVYLKK----KDPSLQVQLLEY 443
+SQFWY ETA +AEE++ + R+AC++ P++Y LK+ + + LLE+
Sbjct: 1 MSQFWYSEETASRLAEELLQQAGEHG--RIACLSAPSVYQKLKQLESVRSDGVSAVLLEF 58
Query: 444 DMRFERYGSEFTFYDYNEPEDLPPQ-LKHCFHIIVADPPYLSKECLERVTQTVSFLASPV 620
D RF YG EF FYDYN P LP L F I++ADPPYLS+ECL +VT TV L
Sbjct: 59 DRRFAAYGDEFVFYDYNNPLCLPEDLLPQSFDIVIADPPYLSEECLSKVTLTVKHLTK-- 116
Query: 621 DSLLLLLTGDVQRDRAAELLGVRPCVFKPHHSSKLGNEFRLFISYD 758
+LL TG + + A +LL ++ C F P H+ L NEFR +++Y+
Sbjct: 117 -GKILLCTGAIMEEHAGKLLDLKMCSFLPRHNHNLANEFRCYVNYE 161
>sp|Q5WRN3|N6MT2_CAEEL N(6)-adenine-specific DNA methyltransferase 2 homolog
OS=Caenorhabditis elegans GN=M142.8 PE=2 SV=1
Length = 218
Score = 129 bits (322), Expect = 9e-029
Identities = 73/211 (34%), Positives = 115/211 (54%), Gaps = 16/211 (7%)
Frame = +3
Query: 147 LSSQALAALQEFLADQNKTVTVTPPPSTVDGGDKVELVTEDWRLSQFWYEPETAETVAEE 326
LS+ LAAL F A+Q + + + G +E + EDW+LSQFWY+ ET+ + E
Sbjct: 10 LSADTLAALSMFQAEQQEKI------EQLQSG-IIEKIDEDWQLSQFWYDDETSRKLVAE 62
Query: 327 VVTLS---NRFSGCRVACIACPTLYVYLKK----KDPSLQVQLLEYDMRFE-RYGSEFTF 482
V + + R+ C++ PTL + + K +Q+ L E+D RF ++ +EF
Sbjct: 63 GVAAALEGSEARPARIGCVSSPTLVKFFHETEEYKTGQIQLTLFEFDDRFGLKFPTEFVH 122
Query: 483 YDYNEPEDLPPQLKHCFHIIVADPPYLSKECLERVTQTVSFLASPVDSLLLLLTGDVQRD 662
YDY P DLP +L F +I+ADPP+L+ ECL + ++ L D +LL TG + D
Sbjct: 123 YDYKHPTDLPAELLAKFDVIIADPPFLAAECLIKTAHSIRLLGKS-DVKVLLCTGAIMED 181
Query: 663 RAAELLGVRPCVFKPHHSSKLGNEFRLFISY 755
A+ L+ + F+P H++ L N+F F +Y
Sbjct: 182 YASRLMAMHRTSFEPRHANNLANDFSCFANY 212
>sp|Q86A24|N6MT2_DICDI N(6)-adenine-specific DNA methyltransferase 2 homolog
OS=Dictyostelium discoideum GN=DDB_G0272708 PE=3 SV=1
Length = 211
Score = 126 bits (314), Expect = 8e-028
Identities = 80/188 (42%), Positives = 112/188 (59%), Gaps = 10/188 (5%)
Frame = +3
Query: 231 VDGGDKVELVTEDWRLSQFWYEPETAETVAEEVVTLSNRFSGCRVACIACPTLYVYL-KK 407
V+ DK E ++EDW+LSQFWYE ET++ VA V G V C++ P++Y L K
Sbjct: 28 VEQQDKFE-ISEDWQLSQFWYEEETSKFVAN--VIEQETIGGNVVVCLSTPSIYKVLHKN 84
Query: 408 KDPSLQVQLLEYDMRFERYGSEFTFYDYNEPED-LPPQLKHCFHIIVADPPYLSKECLER 584
+ L L EYD RF+ YG +F FYDYN PED + QLK I DPP+LS+EC+E+
Sbjct: 85 NNLLLNNNLFEYDKRFDVYGEKFHFYDYNNPEDGISEQLKGNVDYICLDPPFLSEECIEK 144
Query: 585 VTQTVSFLASPVDSLLLLLTGDVQRDRAAELL-GVRPCVFKPHHSSKLGNEFRLFISYDP 761
V +T++ L P + LLLLTG +Q + + L + C F+P H +L N+F +Y
Sbjct: 145 VAKTIALLRKPT-TRLLLLTGRIQWNNIQKYLPEMMICEFEPKH-PRLQNDFFCCSNYH- 201
Query: 762 GTRLGGLE 785
++L GLE
Sbjct: 202 -SKLLGLE 208
>sp|P53200|AML1_YEAST N(6)-adenine-specific DNA methyltransferase-like 1
OS=Saccharomyces cerevisiae GN=AML1 PE=1 SV=2
Length = 248
Score = 85 bits (208), Expect = 2e-015
Identities = 44/132 (33%), Positives = 74/132 (56%), Gaps = 8/132 (6%)
Frame = +3
Query: 249 VELVTEDWRLSQFWYEPETAETVAEEVVTLSNRFSGCRVACIACPTLYVYLKKKD----P 416
++L EDW+LSQFWY +TA +A+ + L +A ++ P++Y ++KK P
Sbjct: 56 MKLFKEDWQLSQFWYSDDTAAILADAI--LEGADENTVIAIVSAPSVYAAIQKKPTNEIP 113
Query: 417 SLQVQLLEYDMRFERYG--SEFTFYDYNEPEDLPPQLKHCFHIIVADPPYLSKECLERVT 590
+ + L E+D RFE F FYDYN+P D ++K ++ DPP+L+++C + +
Sbjct: 114 TEHIYLFEFDKRFELLAGRDHFFFYDYNKPLDFSDEIKGKVDRLLIDPPFLNEDCQTKSS 173
Query: 591 QTVSFLASPVDS 626
T L +P D+
Sbjct: 174 ITAKCLLAPNDN 185
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,258,910,609
Number of Sequences: 518415
Number of Extensions: 62258910609
Number of Successful Extensions: 414452045
Number of sequences better than 0.0: 0
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