BLASTX 7.6.2
Query= UN15400 /QuerySize=912
(911 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q503V9|ENDUB_DANRE Poly(U)-specific endoribonuclease-B OS=Dan... 161 6e-039
sp|B1H3D5|ENDOU_XENTR Poly(U)-specific endoribonuclease OS=Xenop... 153 3e-036
sp|Q8JFY9|ENDUA_XENLA Poly(U)-specific endoribonuclease-A OS=Xen... 152 4e-036
sp|B1WBB4|ENDUB_XENLA Poly(U)-specific endoribonuclease-B OS=Xen... 152 4e-036
sp|Q1LUM3|ENDUC_DANRE Poly(U)-specific endoribonuclease-C OS=Dan... 148 5e-035
sp|P21128|ENDOU_HUMAN Poly(U)-specific endoribonuclease OS=Homo ... 148 7e-035
sp|Q3V188|ENDOU_MOUSE Poly(U)-specific endoribonuclease OS=Mus m... 142 5e-033
sp|A6QLQ8|ENDOU_BOVIN Poly(U)-specific endoribonuclease OS=Bos t... 134 1e-030
sp|A1L237|ENDUA_DANRE Poly(U)-specific endoribonuclease-A OS=Dan... 129 3e-029
sp|Q9PTU6|ENDOU_PAROL Poly(U)-specific endoribonuclease OS=Paral... 119 3e-026
sp|Q9VZ49|ENDOU_DROME Poly(U)-specific endoribonuclease homolog ... 111 9e-024
sp|Q21109|ENDOU_CAEEL Poly(U)-specific endoribonuclease homolog ... 101 1e-020
>sp|Q503V9|ENDUB_DANRE Poly(U)-specific endoribonuclease-B OS=Danio rerio
GN=endoub PE=2 SV=1
Length = 282
Score = 161 bits (407), Expect = 6e-039
Identities = 80/193 (41%), Positives = 110/193 (56%), Gaps = 5/193 (2%)
Frame = -1
Query: 797 EVVTQEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRGG 618
E+VT EE E F++ + +T +K HKYL K ++P FK+ L +WF+LY R G
Sbjct: 86 EIVTPEEEMENHRFLDSVIKTPTMKIAHKYLVEKRLSPEDTTGFKQQLYKIWFELYARKG 145
Query: 617 TS-GSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRRGEIPDS 441
+S SS FEHVFVGE + GG V GFHNW+Q YL+E G +DY+GY + PD
Sbjct: 146 SSKPDSSGFEHVFVGETR--GGHTVIGFHNWIQLYLQEKLGHIDYKGYSVNANSPQ-PDE 202
Query: 440 ETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFMG-REDNHIQLGPYSVNVKCY 264
+L +QF W +K S +GVSPEFE +LYT+CF M E + Y V + C+
Sbjct: 203 NKHMLALQFSWKNGIKPKGSIFIGVSPEFEFSLYTLCFLMSPNERVKVSFNLYDVEIVCH 262
Query: 263 RLGNNRIGSAFPI 225
IG+ +P+
Sbjct: 263 HYNQKHIGTTYPV 275
>sp|B1H3D5|ENDOU_XENTR Poly(U)-specific endoribonuclease OS=Xenopus tropicalis
GN=endou PE=2 SV=1
Length = 293
Score = 153 bits (384), Expect = 3e-036
Identities = 81/195 (41%), Positives = 118/195 (60%), Gaps = 8/195 (4%)
Frame = -1
Query: 797 EVVTQEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRG- 621
EVVT EE E F++ I T V+K H YL K+ A S +FK L ++WF LY R
Sbjct: 93 EVVTPEEIAENNTFLDAILETKVMKIAHDYLVRKNQAKPSRNDFKAQLYTIWFQLYSRAP 152
Query: 620 GTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRRGEIPDS 441
G S FEHVFVGE K+ G+++ G HNW+QFYL+E + ++DY+GY+ R+ PD
Sbjct: 153 GQGPDSCGFEHVFVGESKR--GKEIMGLHNWVQFYLQEKRKTIDYKGYV-GRQNKSRPDH 209
Query: 440 ETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFMGRED---NHIQLGPYSVNVK 270
+ Q+L +QF W ++K + S+ +GVSPEFE ALYT+ F +E +++ Y + +
Sbjct: 210 DDQVLNLQFSWKEMVKPIGSSFIGVSPEFEFALYTVVFLTSQEKMTREVVRVEEYEMQIV 269
Query: 269 CYRLGNNRIGSAFPI 225
R G IG+A+P+
Sbjct: 270 VNRHG-RYIGTAYPV 283
>sp|Q8JFY9|ENDUA_XENLA Poly(U)-specific endoribonuclease-A OS=Xenopus laevis
GN=endou-a PE=1 SV=1
Length = 292
Score = 152 bits (383), Expect = 4e-036
Identities = 82/195 (42%), Positives = 119/195 (61%), Gaps = 8/195 (4%)
Frame = -1
Query: 797 EVVTQEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRG- 621
EVVT EE E F++ I T V+K H YL K+ A + +FK L ++WF LY R
Sbjct: 92 EVVTPEEIAENNNFLDAILETKVMKMAHDYLVRKNQAKPTRNDFKVQLYNIWFQLYSRAP 151
Query: 620 GTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRRGEIPDS 441
G+ S FEHVFVGE K+ G+++ G HNW+QFYL+E + ++DY+GY+ R+ PD
Sbjct: 152 GSRPDSCGFEHVFVGESKR--GQEMMGLHNWVQFYLQEKRKNIDYKGYV-ARQNKSRPDE 208
Query: 440 ETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFMGRED---NHIQLGPYSVNVK 270
+ Q+L +QF W ++K V S+ +GVSPEFE ALYT+ F +E ++L Y + +
Sbjct: 209 DDQVLNLQFNWKEMVKPVGSSFIGVSPEFEFALYTIVFLASQEKMSREVVRLEEYELQIV 268
Query: 269 CYRLGNNRIGSAFPI 225
R G IG+A+P+
Sbjct: 269 VNRHG-RYIGTAYPV 282
>sp|B1WBB4|ENDUB_XENLA Poly(U)-specific endoribonuclease-B OS=Xenopus laevis
GN=endou-b PE=2 SV=1
Length = 292
Score = 152 bits (383), Expect = 4e-036
Identities = 87/196 (44%), Positives = 119/196 (60%), Gaps = 12/196 (6%)
Frame = -1
Query: 797 EVVTQEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRG- 621
EVVT EE E F++ I T V+K H YL K+ A S +FK L S+WF LY R
Sbjct: 92 EVVTPEEIAENNNFLDAILETKVMKMAHDYLVRKNQAKPSQNDFKVQLYSIWFQLYSRAP 151
Query: 620 GTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRRGEIPDS 441
G+ S FEHVFVGE K+ G+++ G HNW+QFYL+E + ++DY+GY+ R+ PD
Sbjct: 152 GSRPDSCGFEHVFVGESKR--GKEMMGLHNWVQFYLQEKRKNIDYKGYV-ARQNKSRPDE 208
Query: 440 ETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFF-----MGREDNHIQLGPYSVN 276
+ Q+L +QF W ++K V S+ +GVSPEFE ALYT+ F M RE I+L Y +
Sbjct: 209 DDQVLNLQFSWKEMVKPVGSSFIGVSPEFEFALYTIVFLASQAKMSRE--VIRLEEYELQ 266
Query: 275 VKCYRLGNNRIGSAFP 228
+ R G IG+A+P
Sbjct: 267 IVVNRHG-RYIGTAYP 281
>sp|Q1LUM3|ENDUC_DANRE Poly(U)-specific endoribonuclease-C OS=Danio rerio
GN=endouc PE=2 SV=1
Length = 309
Score = 148 bits (373), Expect = 5e-035
Identities = 81/194 (41%), Positives = 117/194 (60%), Gaps = 9/194 (4%)
Frame = -1
Query: 797 EVVTQEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRGG 618
E VT EE E +F++ I TAV+K H+YL K + ++FK L +WF LY R
Sbjct: 111 ERVTAEEVTENNSFLDAILETAVMKRAHQYLIGKGKSRSDLRQFKSQLYYMWFRLYHRER 170
Query: 617 TSG-SSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRRGEIPDS 441
G SS FEHVFVGE K G ++ G HNW+QFYL+E + +DY+GY R ++PD+
Sbjct: 171 NGGEDSSGFEHVFVGETK--FGREIMGLHNWVQFYLQEKQNLLDYKGY--KARANDVPDA 226
Query: 440 ETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFMGREDNH---IQLGPYSVNVK 270
+ +L +QF W+G++K V+S VGVSPEFE+A++T+ F E + L Y + +
Sbjct: 227 DDHVLNVQFSWHGLVKPVASAFVGVSPEFEMAVFTILFLTSTEKTTTAVVNLDEYQLEMV 286
Query: 269 CYRLGNNRIGSAFP 228
+R G IG+A+P
Sbjct: 287 VHRHG-RCIGTAYP 299
>sp|P21128|ENDOU_HUMAN Poly(U)-specific endoribonuclease OS=Homo sapiens
GN=ENDOU PE=1 SV=2
Length = 410
Score = 148 bits (372), Expect = 7e-035
Identities = 87/210 (41%), Positives = 121/210 (57%), Gaps = 12/210 (5%)
Frame = -1
Query: 857 KPTFARSAR-ARQLQPARRYKEVVTQEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPG 681
KPT+A Q A + E + +E EQ AF+ EI +TAV+K L+ +L ++ G
Sbjct: 196 KPTYAAFINLLNNYQRATGHGEHFSAQELAEQDAFLREIMKTAVMKELYSFLHHQN-RYG 254
Query: 680 SYQEFKRMLTSLWFDLYGRGGTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAK 501
S QEF L ++WF LY RG G SS FEHVF GE+K+ +V+GFHNW++FYLEE +
Sbjct: 255 SEQEFVDDLKNMWFGLYSRGNEEGDSSGFEHVFSGEVKK---GKVTGFHNWIRFYLEEKE 311
Query: 500 GSVDYQGYIFPRRRGEIPDSETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFM 321
G VDY +I+ PD +L +QF W+G K V S +G SPEFE ALY++C F+
Sbjct: 312 GLVDYYSHIYDGPWDSYPD----VLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLC-FI 366
Query: 320 GREDN--HIQLGPYSVNVKCYRLGNNRIGS 237
R + LG Y + V+ Y + G+
Sbjct: 367 ARPGKVCQLSLGGYPLAVRTYTWDKSTYGN 396
>sp|Q3V188|ENDOU_MOUSE Poly(U)-specific endoribonuclease OS=Mus musculus
GN=Endou PE=2 SV=1
Length = 412
Score = 142 bits (356), Expect = 5e-033
Identities = 79/209 (37%), Positives = 118/209 (56%), Gaps = 10/209 (4%)
Frame = -1
Query: 857 KPTFARSAR-ARQLQPARRYKEVVTQEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPG 681
KPT+A Q A + E + ++ +EQ F+ E+ +TAV+K L+ +L ++
Sbjct: 197 KPTYAAFINLLNNYQRATGHGEHFSAQQLEEQGVFLREVMKTAVMKELYSFLHHQN-RYS 255
Query: 680 SYQEFKRMLTSLWFDLYGRGGTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAK 501
S QEF L ++WF LY RG G SS FEHVF GE+K+ +V+GFHNW++FYL+E +
Sbjct: 256 SEQEFVDDLKNMWFGLYSRGNDEGDSSGFEHVFSGEVKK---GKVTGFHNWIRFYLQEKE 312
Query: 500 GSVDYQGYIFPRRRGEIPDSETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFF- 324
G +DY + + PD +L +QF W+G K V S +G SPEFE ALY++CF
Sbjct: 313 GLLDYYSHNYDGPWDSYPD----VLAMQFNWDGYYKEVGSVFIGSSPEFEFALYSLCFIT 368
Query: 323 MGREDNHIQLGPYSVNVKCYRLGNNRIGS 237
+ H+ LG Y + ++ Y G+
Sbjct: 369 RPGKKCHLSLGGYPLAIQTYTWDKTTYGN 397
>sp|A6QLQ8|ENDOU_BOVIN Poly(U)-specific endoribonuclease OS=Bos taurus GN=ENDOU
PE=2 SV=1
Length = 413
Score = 134 bits (335), Expect = 1e-030
Identities = 80/223 (35%), Positives = 119/223 (53%), Gaps = 17/223 (7%)
Frame = -1
Query: 857 KPTFARSAR-ARQLQPARRYKEVVTQEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPG 681
KPT++ Q A E T +E EQ F+ EI +TAV+K L+ +L ++
Sbjct: 198 KPTYSAFLNLLNNYQRATGRGEHFTAQELAEQDTFLREIMKTAVMKELYGFLHQQN-RYS 256
Query: 680 SYQEFKRMLTSLWFDLYGRGGTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAK 501
S QEF L ++WF LY R SS FEHVF GE+K+ +V+GFHNW++FY++E +
Sbjct: 257 SEQEFVSDLKNMWFGLYSRSKEERDSSGFEHVFSGEVKK---GKVTGFHNWIRFYMQEKE 313
Query: 500 GSVDYQGYIFPRRRGEIPDSETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFF- 324
G VDY +I+ PD +L +QF W+G K V S +G SPEFE ALY++CF
Sbjct: 314 GLVDYYSHIYDGPWDSYPD----VLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIA 369
Query: 323 -------MGREDNHIQLGPYSVNVKCYRLGNNRIGSAFPIAES 216
+ + + + Y+ N Y G I +A+ ++ +
Sbjct: 370 RPGKVCQLSLGGHPLAIQTYTWNKSTYGNGKKYIATAYVVSST 412
>sp|A1L237|ENDUA_DANRE Poly(U)-specific endoribonuclease-A OS=Danio rerio
GN=endoua PE=2 SV=1
Length = 303
Score = 129 bits (324), Expect = 3e-029
Identities = 87/237 (36%), Positives = 126/237 (53%), Gaps = 30/237 (12%)
Frame = -1
Query: 887 YSLWGATSLQKPTFARSARARQLQPARRYK------EVVTQEERQEQAAFIEEISRTAVV 726
+ + +T L KPT+ L YK E V E QEQ +F+++ T +
Sbjct: 79 FKVVSSTLLSKPTYEAF-----LDLLDNYKKMTGEVEDVPSHEEQEQDSFLQQTMNTNLG 133
Query: 725 KYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRG-GTSGSSSAFEHVFVGEIKQCGGEQ 549
K L +L K V GS EF + L +WF LY R G SS FEH+FVGEIK G +
Sbjct: 134 KELFNFLHSKGVY-GSQSEFLQDLKMMWFGLYSRSDGVKLDSSGFEHIFVGEIK---GGK 189
Query: 548 VSGFHNWLQFYLEEAKGSVDYQGYIFPRRRGEIPDSETQLLTIQFEWNGVLKSVSSTLVG 369
VSGFH+W+QFY E +G ++Y + F PD +L +QF W+G K + S +G
Sbjct: 190 VSGFHSWVQFYQCEKQGILNYYSHSFDGPWTTYPD----VLGMQFNWDGYFKELGSAFIG 245
Query: 368 VSPEFELALYTMCFFM--GREDNHIQLGPYSVNVKCYRL-------GNNRIGSAFPI 225
SPEF+LA+Y++C+ G++ + + LG +S+ ++ Y G IGSA+PI
Sbjct: 246 CSPEFDLAIYSLCYITRPGKKCD-VSLGGHSLGIQTYTWDKSSYGDGKKFIGSAYPI 301
>sp|Q9PTU6|ENDOU_PAROL Poly(U)-specific endoribonuclease OS=Paralichthys
olivaceus GN=endou PE=2 SV=1
Length = 385
Score = 119 bits (297), Expect = 3e-026
Identities = 81/226 (35%), Positives = 115/226 (50%), Gaps = 22/226 (9%)
Frame = -1
Query: 869 TSLQKPTFAR-SARARQLQPARRYKEVVTQEERQEQAAFIEE-ISRTAVVKYLHKYLAIK 696
T L +PT+A A E + ++ EQ FI+E +S T + + L +L K
Sbjct: 167 TLLSRPTYAAFLAVLDNYHRMTGQVEDFSPQQLSEQETFIKEAMSNTELGRELFAFLYTK 226
Query: 695 DVAPGSYQEFKRMLTSLWFDLYGRGGTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFY 516
V S EF L +WF LY R SS FEH+F GEIK G +VSGFHNW+QFY
Sbjct: 227 GVY-ASENEFLHDLKMMWFGLYSRYNNKMDSSGFEHIFAGEIK---GGKVSGFHNWIQFY 282
Query: 515 LEEAKGSVDYQGYIFPRRRGEIPDSETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYT 336
E +G ++Y + F PD ++ +QF+W+G K V S ++G SPEF+ ALY+
Sbjct: 283 RLEKRGQLNYYSHSFNGPWTTFPD----VMGMQFKWDGYFKQVGSAVIGCSPEFDFALYS 338
Query: 335 MCFF----------MGREDNHIQLGPYSVNVKCYRLGNNRIGSAFP 228
+C+ +G ++ IQ Y+ + Y G I SAFP
Sbjct: 339 LCYITRPGKQCRLSLGGKELIIQ--TYTWDKTTYGNGKKFIASAFP 382
>sp|Q9VZ49|ENDOU_DROME Poly(U)-specific endoribonuclease homolog OS=Drosophila
melanogaster GN=CG2145 PE=1 SV=1
Length = 592
Score = 111 bits (276), Expect = 9e-024
Identities = 71/195 (36%), Positives = 103/195 (52%), Gaps = 13/195 (6%)
Frame = -1
Query: 797 EVVTQEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRGG 618
E VT ER+E+ F++ + T V++ +L K V + + ++ LWF Y RG
Sbjct: 404 EHVTPNERKEENDFLDAVMATPVMRQAMLFLQQKGVVSPDPKTHRDLVKELWFTQYSRGQ 463
Query: 617 TSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRRGEIPDSE 438
SS FEHVFV E+K + GFHNW+ EE G DY+GY+ + G ++
Sbjct: 464 GKIGSSGFEHVFVYEVKD---GTIIGFHNWVYIGDEEKDGRFDYKGYMKEQDIG----TK 516
Query: 437 TQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFMGREDN--HIQLGPYSVNVKCY 264
+++ I+F G+ K V++ VG SPE ELALYT+CF + R D + LG + Y
Sbjct: 517 GKIVKIRFSHQGLNKPVNTVFVGTSPELELALYTVCFQL-RPDRTCPVSLGNSKFGIVTY 575
Query: 263 R---LGNNRIGSAFP 228
G N IGSA+P
Sbjct: 576 SWRYRGKNLIGSAYP 590
>sp|Q21109|ENDOU_CAEEL Poly(U)-specific endoribonuclease homolog
OS=Caenorhabditis elegans GN=K02A11.3 PE=1 SV=1
Length = 307
Score = 101 bits (249), Expect = 1e-020
Identities = 62/195 (31%), Positives = 98/195 (50%), Gaps = 19/195 (9%)
Frame = -1
Query: 782 EERQEQAAFIEEISRTAVVKYLHKYLAIK-DVAPGSYQEFKRMLTSLWFDLYGRGGTSGS 606
EE+ E F++ + + ++ L+ + K S Q F+ + LWF Y R
Sbjct: 110 EEKNEVGKFLDYVLESRPMQELYNWFKAKGHPIATSPQVFRFWIGQLWFSHYSRALGRPD 169
Query: 605 SSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEE--AKGSVDYQGYIFPRRRGEIPDSETQ 432
+S FEHVF+GE K ++SG HNW++FY+ E + DY+G+ R
Sbjct: 170 TSGFEHVFIGEAK---NGEISGMHNWVRFYVLENNRTENFDYKGFTVKR--------FNI 218
Query: 431 LLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFF--MGREDNHIQLGPYSVNVKCYRL 258
+ ++F W+G+LK S L+G SPEF++ALYTMCF GRE ++ + + + +
Sbjct: 219 MAALKFTWDGLLKRAGSILIGTSPEFDMALYTMCFLSRRGRETCDVEFDGCPLQITSFEI 278
Query: 257 GNNR---IGSAFPIA 222
IGS +P A
Sbjct: 279 MQQNKVYIGSIYPTA 293
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,258,910,609
Number of Sequences: 518415
Number of Extensions: 62258910609
Number of Successful Extensions: 414452045
Number of sequences better than 0.0: 0
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