BLASTX 7.6.2
Query= UN15671 /QuerySize=1085
(1084 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q1ZXQ4|FCSB_DICDI Fatty acyl-CoA synthetase B OS=Dictyosteliu... 224 1e-057
sp|Q9ULC5|ACSL5_HUMAN Long-chain-fatty-acid--CoA ligase 5 OS=Hom... 223 3e-057
sp|Q8JZR0|ACSL5_MOUSE Long-chain-fatty-acid--CoA ligase 5 OS=Mus... 223 3e-057
sp|O88813|ACSL5_RAT Long-chain-fatty-acid--CoA ligase 5 OS=Rattu... 220 2e-056
sp|P41216|ACSL1_MOUSE Long-chain-fatty-acid--CoA ligase 1 OS=Mus... 205 5e-052
sp|P33121|ACSL1_HUMAN Long-chain-fatty-acid--CoA ligase 1 OS=Hom... 204 1e-051
sp|Q9JID6|ACSL1_CAVPO Long-chain-fatty-acid--CoA ligase 1 OS=Cav... 203 2e-051
sp|P18163|ACSL1_RAT Long-chain-fatty-acid--CoA ligase 1 OS=Rattu... 203 3e-051
sp|Q55DR6|FCSA_DICDI Fatty acyl-CoA synthetase A OS=Dictyosteliu... 202 5e-051
sp|Q9UKU0|ACSL6_HUMAN Long-chain-fatty-acid--CoA ligase 6 OS=Hom... 200 1e-050
sp|Q91WC3|ACSL6_MOUSE Long-chain-fatty-acid--CoA ligase 6 OS=Mus... 198 1e-049
sp|P33124|ACSL6_RAT Long-chain-fatty-acid--CoA ligase 6 OS=Rattu... 198 1e-049
sp|Q63151|ACSL3_RAT Long-chain-fatty-acid--CoA ligase 3 OS=Rattu... 162 5e-039
sp|Q9CZW4|ACSL3_MOUSE Long-chain-fatty-acid--CoA ligase 3 OS=Mus... 162 6e-039
sp|O95573|ACSL3_HUMAN Long-chain-fatty-acid--CoA ligase 3 OS=Hom... 161 1e-038
sp|Q5R668|ACSL3_PONAB Long-chain-fatty-acid--CoA ligase 3 OS=Pon... 161 1e-038
sp|O35547|ACSL4_RAT Long-chain-fatty-acid--CoA ligase 4 OS=Rattu... 156 3e-037
sp|O60488|ACSL4_HUMAN Long-chain-fatty-acid--CoA ligase 4 OS=Hom... 156 4e-037
sp|Q9QUJ7|ACSL4_MOUSE Long-chain-fatty-acid--CoA ligase 4 OS=Mus... 156 4e-037
sp|O60135|LCF1_SCHPO Long-chain-fatty-acid--CoA ligase 1 OS=Schi... 150 2e-035
>sp|Q1ZXQ4|FCSB_DICDI Fatty acyl-CoA synthetase B OS=Dictyostelium discoideum
GN=fcsB PE=2 SV=1
Length = 673
Score = 224 bits (569), Expect = 1e-057
Identities = 111/262 (42%), Positives = 165/262 (62%), Gaps = 1/262 (0%)
Frame = +3
Query: 3 PLSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVA 182
PLS + E FLRV CC V+QGYG +E GG A D+ +GT+G P NEI+L +V
Sbjct: 412 PLSFDTEVFLRVVMCCCVLQGYGASEGCGGDACKRLDDE-SVGTIGPPFASNEIKLVDVP 470
Query: 183 EMGYDPLGENPAGEICIRGKCLFSGYYKNPELTQEVMKDGWFHTGDIGEIQSNGVLKIID 362
E+GYD GE GE+C+RG + SGYYK+ E T+E KDGWFHTGDIG +G L I+D
Sbjct: 471 ELGYDSNGEVQTGEVCLRGPSISSGYYKDEEKTREEFKDGWFHTGDIGRWNRDGSLSIVD 530
Query: 363 RKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAKE 542
RKKN+ KLSQGEYVA+E +E I ++ V+ + +YGDS KS ++A+I P+ E+ WA
Sbjct: 531 RKKNIFKLSQGEYVAVEKIETIVVKSEYVEQVCIYGDSQKSCVIAIIHPHPESCSEWAGS 590
Query: 543 LGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTATL 722
K +E+C + + ++ ++ +K+ L FE KA+ + + F +L+T +
Sbjct: 591 KKTDKDIKEICKNQDFIKVVLDDIIKNCKKSGLHGFEIPKAIHLTPEAFSDQNNLLTPSF 650
Query: 723 KNRRNNLLKYYQVHVEEMYRKL 788
K +R+ + KY++ ++++Y KL
Sbjct: 651 KLKRHEIKKYFEDEIKKLYSKL 672
>sp|Q9ULC5|ACSL5_HUMAN Long-chain-fatty-acid--CoA ligase 5 OS=Homo sapiens
GN=ACSL5 PE=1 SV=1
Length = 683
Score = 223 bits (566), Expect = 3e-057
Identities = 111/263 (42%), Positives = 164/263 (62%), Gaps = 4/263 (1%)
Frame = +3
Query: 3 PLSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVA 182
P+ST + F R C V + YG TE GG P + G VG+P N ++LE+VA
Sbjct: 422 PMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTS-GHVGVPLACNYVKLEDVA 480
Query: 183 EMGYDPLGENPAGEICIRGKCLFSGYYKNPELTQEVM-KDGWFHTGDIGEIQSNGVLKII 359
+M Y + N GE+CI+G +F GY K+PE TQE + DGW HTGDIG NG LKII
Sbjct: 481 DMNYFTV--NNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKII 538
Query: 360 DRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAK 539
DRKKN+ KL+QGEY+A E +ENIY ++ V I+V+G+S +S LV V+VP+ + + +A
Sbjct: 539 DRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAA 598
Query: 540 ELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTAT 719
+LG FEELC ++E I+ +L+ +++ L+ FE +KA+ + +PF + L+T T
Sbjct: 599 KLGVKGSFEELCQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPT 658
Query: 720 LKNRRNNLLKYYQVHVEEMYRKL 788
LK +R L KY++ ++ +Y +
Sbjct: 659 LKAKRGELSKYFRTQIDSLYEHI 681
>sp|Q8JZR0|ACSL5_MOUSE Long-chain-fatty-acid--CoA ligase 5 OS=Mus musculus
GN=Acsl5 PE=2 SV=1
Length = 683
Score = 223 bits (566), Expect = 3e-057
Identities = 109/263 (41%), Positives = 167/263 (63%), Gaps = 4/263 (1%)
Frame = +3
Query: 3 PLSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVA 182
P+ST + F R C+V + YG TE GG ++ P + G VG P N ++LE+VA
Sbjct: 422 PISTPVLTFFRAAMGCWVFEAYGQTECTGGCSITSPGDW-TAGHVGTPVACNFVKLEDVA 480
Query: 183 EMGYDPLGENPAGEICIRGKCLFSGYYKNPELTQEVM-KDGWFHTGDIGEIQSNGVLKII 359
+M Y N GEICI+G +F GY K+PE TQEV+ KDGW HTGDIG NG LKI+
Sbjct: 481 DMNY--FSVNNEGEICIKGNNVFKGYLKDPEKTQEVLDKDGWLHTGDIGRWLPNGTLKIV 538
Query: 360 DRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAK 539
DRKKN+ KL+QGEY+A E +EN+Y ++ V ++V+G+S +S L+ V+VP+ +++ +A
Sbjct: 539 DRKKNIFKLAQGEYIAPEKIENVYSRSRPVLQVFVHGESLRSFLIGVVVPDPDSLPSFAA 598
Query: 540 ELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTAT 719
++G FEELC ++E I+ +L+ ++ L+ FE +K++ V +PF + L+T T
Sbjct: 599 KIGVKGSFEELCKNQCVKEAILEDLQKIGKEGGLKSFEQVKSIFVHPEPFTIENGLLTPT 658
Query: 720 LKNRRNNLLKYYQVHVEEMYRKL 788
LK +R L K++Q ++ +Y +
Sbjct: 659 LKAKRVELAKFFQTQIKSLYESI 681
>sp|O88813|ACSL5_RAT Long-chain-fatty-acid--CoA ligase 5 OS=Rattus norvegicus
GN=Acsl5 PE=2 SV=1
Length = 683
Score = 220 bits (559), Expect = 2e-056
Identities = 108/263 (41%), Positives = 166/263 (63%), Gaps = 4/263 (1%)
Frame = +3
Query: 3 PLSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVA 182
P+ST + F R C+V + YG TE G ++ P + G VG P N ++LE+VA
Sbjct: 422 PISTPVLTFFRAAMGCWVFEAYGQTECTAGCSITSPGDW-TAGHVGTPVSCNFVKLEDVA 480
Query: 183 EMGYDPLGENPAGEICIRGKCLFSGYYKNPELTQEVM-KDGWFHTGDIGEIQSNGVLKII 359
+M Y N GEICI+G +F GY K+PE TQEV+ KDGW HTGDIG NG LKII
Sbjct: 481 DMNY--FSVNNEGEICIKGNNVFKGYLKDPEKTQEVLDKDGWLHTGDIGRWLPNGTLKII 538
Query: 360 DRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAK 539
DRKKN+ KL+QGEY+A E +EN+Y ++ + ++V+G+S +S L+ V+VP+ E++ +A
Sbjct: 539 DRKKNIFKLAQGEYIAPEKIENVYSRSRPILQVFVHGESLRSFLIGVVVPDPESLPSFAA 598
Query: 540 ELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTAT 719
++G FEELC +++ I+ +L+ ++ L+ FE +K++ V +PF + L+T T
Sbjct: 599 KIGVKGSFEELCQNQCVKKAILEDLQKVGKEGGLKSFEQVKSIFVHPEPFSIENGLLTPT 658
Query: 720 LKNRRNNLLKYYQVHVEEMYRKL 788
LK +R L K++Q ++ +Y +
Sbjct: 659 LKAKRVELAKFFQTQIKSLYESI 681
>sp|P41216|ACSL1_MOUSE Long-chain-fatty-acid--CoA ligase 1 OS=Mus musculus
GN=Acsl1 PE=1 SV=1
Length = 699
Score = 205 bits (521), Expect = 5e-052
Identities = 103/260 (39%), Positives = 157/260 (60%), Gaps = 4/260 (1%)
Frame = +3
Query: 3 PLSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVA 182
P+S + FLR C +GYG TE G + P + G VG P N ++L +V
Sbjct: 438 PVSATVLTFLRTALGCQFYEGYGQTECTAGCCLSLPGDW-TAGHVGAPMPCNYVKLVDVE 496
Query: 183 EMGYDPLGENPAGEICIRGKCLFSGYYKNPELTQEVM-KDGWFHTGDIGEIQSNGVLKII 359
EM Y L GE+C++G +F GY K+P T E + KDGW HTGDIG+ NG LKII
Sbjct: 497 EMNY--LASKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKII 554
Query: 360 DRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAK 539
DRKK++ KL+QGEY+A E +ENIY ++ V ++V+G+S ++ L+AV+VP+ E++ WA+
Sbjct: 555 DRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAVVVPDVESLPSWAQ 614
Query: 540 ELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTAT 719
+ G FEELC ++ + I+ +L ++ L+ FE +K + V + F + L+T T
Sbjct: 615 KRGLQGSFEELCRNKDINKAILDDLLKLGKEAGLKPFEQVKGIAVHPELFSIDNGLLTPT 674
Query: 720 LKNRRNNLLKYYQVHVEEMY 779
LK +R L Y++ ++E+Y
Sbjct: 675 LKAKRPELRNYFRSQIDELY 694
>sp|P33121|ACSL1_HUMAN Long-chain-fatty-acid--CoA ligase 1 OS=Homo sapiens
GN=ACSL1 PE=1 SV=1
Length = 698
Score = 204 bits (517), Expect = 1e-051
Identities = 101/260 (38%), Positives = 160/260 (61%), Gaps = 4/260 (1%)
Frame = +3
Query: 3 PLSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVA 182
P+S + FLR C +GYG TE G + P + G VG P N I+L +V
Sbjct: 437 PVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDW-TAGHVGAPMPCNLIKLVDVE 495
Query: 183 EMGYDPLGENPAGEICIRGKCLFSGYYKNPELTQEVM-KDGWFHTGDIGEIQSNGVLKII 359
EM Y + GE+C++G +F GY K+P T E + KDGW HTGDIG+ NG LKII
Sbjct: 496 EMNY--MAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKII 553
Query: 360 DRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAK 539
DRKK++ KL+QGEY+A E +ENIY ++ V ++V+G+S ++ L+A++VP+ ET+ WA+
Sbjct: 554 DRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQ 613
Query: 540 ELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTAT 719
+ GF FEELC ++++ I+ ++ + + L+ FE +K +T+ + F + L+T T
Sbjct: 614 KRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPT 673
Query: 720 LKNRRNNLLKYYQVHVEEMY 779
+K +R L Y++ ++++Y
Sbjct: 674 MKAKRPELRNYFRSQIDDLY 693
>sp|Q9JID6|ACSL1_CAVPO Long-chain-fatty-acid--CoA ligase 1 OS=Cavia porcellus
GN=ACSL1 PE=2 SV=1
Length = 698
Score = 203 bits (515), Expect = 2e-051
Identities = 102/261 (39%), Positives = 162/261 (62%), Gaps = 6/261 (2%)
Frame = +3
Query: 3 PLSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVA 182
P+S + FLR C +GYG TE G ++ P + G VG P N I+L +V
Sbjct: 437 PVSATVLTFLRAALGCQFYEGYGQTECTAGCSLSVPGDW-TAGHVGAPMPCNFIKLVDVE 495
Query: 183 EMGY-DPLGENPAGEICIRGKCLFSGYYKNPELTQEVM-KDGWFHTGDIGEIQSNGVLKI 356
EM Y +GE GE+C++G +F GY K+P T E + KDGW HTGDIG+ NG LKI
Sbjct: 496 EMNYMAAMGE---GEVCVKGPNVFKGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKI 552
Query: 357 IDRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWA 536
IDRKK++ KL+QGEY+A E +ENIY ++ V ++V+G+S ++ L+A++VP+ E++ WA
Sbjct: 553 IDRKKHIFKLAQGEYIAPEKIENIYVRSEPVAQVFVHGESLQAFLIAIVVPDAESLASWA 612
Query: 537 KELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTA 716
++ GF FEELC ++++ I+ ++ + + L+ FE ++ + + + F V L+T
Sbjct: 613 RKRGFEGSFEELCRNKDVKKAILEDMVRIGKDSGLKSFEQVRGIALHPELFSVDNGLLTP 672
Query: 717 TLKNRRNNLLKYYQVHVEEMY 779
T+K +R L Y++ ++E+Y
Sbjct: 673 TMKAKRPELRNYFRSQIDELY 693
>sp|P18163|ACSL1_RAT Long-chain-fatty-acid--CoA ligase 1 OS=Rattus norvegicus
GN=Acsl1 PE=1 SV=1
Length = 699
Score = 203 bits (514), Expect = 3e-051
Identities = 101/260 (38%), Positives = 155/260 (59%), Gaps = 4/260 (1%)
Frame = +3
Query: 3 PLSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVA 182
P+S + FLR C +GYG TE G + P + G VG P N I+L +V
Sbjct: 438 PVSATVLTFLRAALGCQFYEGYGQTECTAGCCLSLPGDW-TAGHVGAPMPCNYIKLVDVE 496
Query: 183 EMGYDPLGENPAGEICIRGKCLFSGYYKNPELTQEVM-KDGWFHTGDIGEIQSNGVLKII 359
+M Y GE+C++G +F GY K+P T E + KDGW HTGDIG+ NG LKII
Sbjct: 497 DMNYQ--AAKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKII 554
Query: 360 DRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAK 539
DRKK++ KL+QGEY+A E +ENIY ++ V ++V+G+S ++ L+A++VP+ E + WA+
Sbjct: 555 DRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAIVVPDVEILPSWAQ 614
Query: 540 ELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTAT 719
+ GF FEELC ++ + I+ ++ + L+ FE +K + V + F + L+T T
Sbjct: 615 KRGFQGSFEELCRNKDINKAILEDMVKLGKNAGLKPFEQVKGIAVHPELFSIDNGLLTPT 674
Query: 720 LKNRRNNLLKYYQVHVEEMY 779
LK +R L Y++ ++E+Y
Sbjct: 675 LKAKRPELRNYFRSQIDELY 694
>sp|Q55DR6|FCSA_DICDI Fatty acyl-CoA synthetase A OS=Dictyostelium discoideum
GN=fcsA PE=1 SV=1
Length = 667
Score = 202 bits (512), Expect = 5e-051
Identities = 113/268 (42%), Positives = 161/268 (60%), Gaps = 16/268 (5%)
Frame = +3
Query: 6 LSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVAE 185
L ++ EFLR CC VV GYGL+E +GG ++ +P++ +G VG P E++L +V E
Sbjct: 396 LDPKLAEFLRACFCCPVVSGYGLSENVGGASVAYPEDN-NVGHVGPPLSACEMKLIDVPE 454
Query: 186 MGYDPLGEN-PAGEICIRGKCLFSGYYKNPELTQEVMK-DGWFHTGDIGEIQSNGVLKII 359
M Y + P GE+CIRG +F GY+K+PE T+E +K DGWFHTGDIG NG L II
Sbjct: 455 MNYFSTDKPCPRGEVCIRGFNVFKGYFKDPEKTKEDLKEDGWFHTGDIGRWNENGTLSII 514
Query: 360 DRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAK 539
DRKKN+ KLSQGEYVA E LE+++ ++ ++VYGDS S LV V+VP+ E V++
Sbjct: 515 DRKKNIFKLSQGEYVAAEYLESVFVRSPFASQVFVYGDSLNSFLVGVVVPDFEVVQKL-- 572
Query: 540 ELGFTKPFEE--------LCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDV 695
F + E L EL + I+S + A + KL FE +K + VE +PF
Sbjct: 573 ---FASKYPELDVSNHATLAKSKELYKEILSSFDACAAEAKLHGFEKLKHIYVEHEPFTE 629
Query: 696 ARDLVTATLKNRRNNLLKYYQVHVEEMY 779
+L+T + K +R L + YQ ++ +Y
Sbjct: 630 ENNLLTPSFKPKRPQLKERYQTIIDTLY 657
>sp|Q9UKU0|ACSL6_HUMAN Long-chain-fatty-acid--CoA ligase 6 OS=Homo sapiens
GN=ACSL6 PE=2 SV=4
Length = 697
Score = 200 bits (508), Expect = 1e-050
Identities = 107/261 (40%), Positives = 158/261 (60%), Gaps = 6/261 (2%)
Frame = +3
Query: 3 PLSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVA 182
P S + FLR C V +GYG TE G P + G VG P N I+L +V
Sbjct: 437 PASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTS-GHVGAPLPCNHIKLVDVE 495
Query: 183 EMGYDPL-GENPAGEICIRGKCLFSGYYKNPELTQEVM-KDGWFHTGDIGEIQSNGVLKI 356
E+ Y GE GEIC+RG +F GY K+P+ T+E + DGW HTGDIG+ G LKI
Sbjct: 496 ELNYWACKGE---GEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKI 552
Query: 357 IDRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWA 536
IDRKK++ KL+QGEYVA E +ENIY ++ V I+V+GDS K+ LV ++VP+ E + WA
Sbjct: 553 IDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWA 612
Query: 537 KELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTA 716
++ G + +LC+ +L++ I+ ++ +++ L FE +KA+ + + F V L+T
Sbjct: 613 QKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTP 672
Query: 717 TLKNRRNNLLKYYQVHVEEMY 779
TLK +R L +Y++ +EE+Y
Sbjct: 673 TLKAKRPELREYFKKQIEELY 693
>sp|Q91WC3|ACSL6_MOUSE Long-chain-fatty-acid--CoA ligase 6 OS=Mus musculus
GN=Acsl6 PE=2 SV=1
Length = 697
Score = 198 bits (501), Expect = 1e-049
Identities = 106/261 (40%), Positives = 155/261 (59%), Gaps = 6/261 (2%)
Frame = +3
Query: 3 PLSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVA 182
P S + FLR C V +GYG TE G P + G VG P N I+L +
Sbjct: 437 PASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTS-GHVGAPLPCNHIKLVDAE 495
Query: 183 EMGY-DPLGENPAGEICIRGKCLFSGYYKNPELTQEVM-KDGWFHTGDIGEIQSNGVLKI 356
E+ Y GE GEIC++G +F GY K+ + T+E + DGW HTGDIG+ G LKI
Sbjct: 496 ELNYWTCKGE---GEICVKGPNVFKGYLKDEDRTKEALDSDGWLHTGDIGKWLPEGTLKI 552
Query: 357 IDRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWA 536
IDRKK++ KL+QGEYVA E +ENIY ++ V I+V+GDS K+ LV ++VP+ E + WA
Sbjct: 553 IDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWA 612
Query: 537 KELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTA 716
++ G ++ELC EL++ I+ ++ +++ L FE +KA+ + F V L+T
Sbjct: 613 QKKGIEGTYQELCMKKELKKAILDDMVMLGKESGLHSFEQVKAIYIHCDMFSVQNGLLTP 672
Query: 717 TLKNRRNNLLKYYQVHVEEMY 779
TLK +R L +Y++ +EE+Y
Sbjct: 673 TLKAKRPELREYFKKQIEELY 693
>sp|P33124|ACSL6_RAT Long-chain-fatty-acid--CoA ligase 6 OS=Rattus norvegicus
GN=Acsl6 PE=1 SV=1
Length = 697
Score = 198 bits (501), Expect = 1e-049
Identities = 106/261 (40%), Positives = 155/261 (59%), Gaps = 6/261 (2%)
Frame = +3
Query: 3 PLSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVA 182
P S + FLR C V +GYG TE G P + G VG P N I+L +
Sbjct: 437 PASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTS-GHVGAPLPCNHIKLVDAE 495
Query: 183 EMGY-DPLGENPAGEICIRGKCLFSGYYKNPELTQEVM-KDGWFHTGDIGEIQSNGVLKI 356
E+ Y GE GEIC++G +F GY K+ + T+E + DGW HTGDIG+ G LKI
Sbjct: 496 ELNYWTSKGE---GEICVKGPNVFKGYLKDEDRTKEALDSDGWLHTGDIGKWLPEGTLKI 552
Query: 357 IDRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWA 536
IDRKK++ KL+QGEYVA E +ENIY ++ V I+V+GDS K+ LV ++VP+ E + WA
Sbjct: 553 IDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIYVHGDSLKAFLVGIVVPDPEVMPCWA 612
Query: 537 KELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTA 716
++ G ++ELC EL++ I+ ++ +++ L FE +KA+ + F V L+T
Sbjct: 613 QKKGIEGNYQELCKSKELKKAILDDMVMLGKESGLHSFEQVKAIYIHCDMFSVQNGLLTP 672
Query: 717 TLKNRRNNLLKYYQVHVEEMY 779
TLK +R L +Y++ +EE+Y
Sbjct: 673 TLKAKRPELREYFKKQIEELY 693
>sp|Q63151|ACSL3_RAT Long-chain-fatty-acid--CoA ligase 3 OS=Rattus norvegicus
GN=Acsl3 PE=1 SV=1
Length = 720
Score = 162 bits (409), Expect = 5e-039
Identities = 99/260 (38%), Positives = 138/260 (53%), Gaps = 9/260 (3%)
Frame = +3
Query: 21 EEFLRVTCCCFVVQGYGLTETLG-GTAMGFPDEMCMLGTVGIPAVYNEIRLEEVAEMGYD 197
+ F+ + CC V QGYGLTE+ G GT D G VG P V EI+L+ E GY
Sbjct: 460 QRFMNICFCCPVGQGYGLTESTGAGTITEVWD--YNTGRVGAPLVCCEIKLKNWEEGGYF 517
Query: 198 PLGE-NPAGEICIRGKCLFSGYYKNPELT-----QEVMKDGWFHTGDIGEIQSNGVLKII 359
+ +P GEI I G+ + GYYKN T ++ W TGDIGE +G LKII
Sbjct: 518 NTDKPHPRGEILIGGQNVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFDPDGCLKII 577
Query: 360 DRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAK 539
DRKK+L+KL GEYV+L +E L+ +I Y +S+ S ++ +VPNQ+ + A+
Sbjct: 578 DRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELAR 637
Query: 540 ELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTAT 719
GF +EELC+ SE++ ++ L A L KFE + + P+ LVT
Sbjct: 638 TKGFNGTWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDA 697
Query: 720 LKNRRNNLLKYYQVHVEEMY 779
K +R L +YQ +E MY
Sbjct: 698 FKLKRKELKTHYQADIERMY 717
>sp|Q9CZW4|ACSL3_MOUSE Long-chain-fatty-acid--CoA ligase 3 OS=Mus musculus
GN=Acsl3 PE=2 SV=1
Length = 720
Score = 162 bits (408), Expect = 6e-039
Identities = 99/260 (38%), Positives = 138/260 (53%), Gaps = 9/260 (3%)
Frame = +3
Query: 21 EEFLRVTCCCFVVQGYGLTETLG-GTAMGFPDEMCMLGTVGIPAVYNEIRLEEVAEMGYD 197
+ F+ + CC V QGYGLTE+ G GT D G VG P V EI+L+ E GY
Sbjct: 460 QRFMNICFCCPVGQGYGLTESTGAGTITEVWD--YNTGRVGAPLVCCEIKLKNWEEGGYF 517
Query: 198 PLGE-NPAGEICIRGKCLFSGYYKNPELT-----QEVMKDGWFHTGDIGEIQSNGVLKII 359
+ +P GEI I G+ + GYYKN T ++ W TGDIGE +G LKII
Sbjct: 518 NTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTGDIGEFDPDGCLKII 577
Query: 360 DRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAK 539
DRKK+L+KL GEYV+L +E L+ +I Y +S+ S ++ +VPNQ+ + A+
Sbjct: 578 DRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELAR 637
Query: 540 ELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTAT 719
GF +EELC+ SE++ ++ L A L KFE + + P+ LVT
Sbjct: 638 TKGFKGTWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDA 697
Query: 720 LKNRRNNLLKYYQVHVEEMY 779
K +R L +YQ +E MY
Sbjct: 698 FKLKRKELKTHYQADIERMY 717
>sp|O95573|ACSL3_HUMAN Long-chain-fatty-acid--CoA ligase 3 OS=Homo sapiens
GN=ACSL3 PE=1 SV=3
Length = 720
Score = 161 bits (406), Expect = 1e-038
Identities = 98/260 (37%), Positives = 139/260 (53%), Gaps = 9/260 (3%)
Frame = +3
Query: 21 EEFLRVTCCCFVVQGYGLTETLG-GTAMGFPDEMCMLGTVGIPAVYNEIRLEEVAEMGYD 197
+ F+ + CC V QGYGLTE+ G GT D G VG P V EI+L+ E GY
Sbjct: 460 QRFMNICFCCPVGQGYGLTESAGAGTISEVWD--YNTGRVGAPLVCCEIKLKNWEEGGYF 517
Query: 198 PLGE-NPAGEICIRGKCLFSGYYKNPELT-----QEVMKDGWFHTGDIGEIQSNGVLKII 359
+ +P GEI I G+ + GYYKN T ++ W TGDIGE + +G LKII
Sbjct: 518 NTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKII 577
Query: 360 DRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAK 539
DRKK+L+KL GEYV+L +E LV +I Y +S+ S ++ +VPNQ+ + A+
Sbjct: 578 DRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELAR 637
Query: 540 ELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTAT 719
+ G +EELC+ E++ ++ L A L KFE + + +P+ LVT
Sbjct: 638 KKGLKGTWEELCNSCEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDA 697
Query: 720 LKNRRNNLLKYYQVHVEEMY 779
K +R L +YQ +E MY
Sbjct: 698 FKLKRKELKTHYQADIERMY 717
>sp|Q5R668|ACSL3_PONAB Long-chain-fatty-acid--CoA ligase 3 OS=Pongo abelii
GN=ACSL3 PE=2 SV=2
Length = 720
Score = 161 bits (406), Expect = 1e-038
Identities = 98/260 (37%), Positives = 139/260 (53%), Gaps = 9/260 (3%)
Frame = +3
Query: 21 EEFLRVTCCCFVVQGYGLTETLG-GTAMGFPDEMCMLGTVGIPAVYNEIRLEEVAEMGYD 197
+ F+ + CC V QGYGLTE+ G GT D G VG P V EI+L+ E GY
Sbjct: 460 QRFMNICFCCPVGQGYGLTESAGAGTISEVWD--YNTGRVGAPLVCCEIKLKNWEEGGYF 517
Query: 198 PLGE-NPAGEICIRGKCLFSGYYKNPELT-----QEVMKDGWFHTGDIGEIQSNGVLKII 359
+ +P GEI I G+ + GYYKN T ++ W TGDIGE + +G LKII
Sbjct: 518 NTDKPHPRGEILIGGQIVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKII 577
Query: 360 DRKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAK 539
DRKK+L+KL GEYV+L +E LV +I Y +S+ S ++ +VPNQ+ + A+
Sbjct: 578 DRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELAR 637
Query: 540 ELGFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTAT 719
+ G +EELC+ E++ ++ L A L KFE + + +P+ LVT
Sbjct: 638 KKGLKGTWEELCNSCEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDA 697
Query: 720 LKNRRNNLLKYYQVHVEEMY 779
K +R L +YQ +E MY
Sbjct: 698 FKLKRKELKTHYQADIERMY 717
>sp|O35547|ACSL4_RAT Long-chain-fatty-acid--CoA ligase 4 OS=Rattus norvegicus
GN=Acsl4 PE=2 SV=1
Length = 670
Score = 156 bits (393), Expect = 3e-037
Identities = 96/258 (37%), Positives = 143/258 (55%), Gaps = 9/258 (3%)
Frame = +3
Query: 27 FLRVTCCCFVVQGYGLTETLG-GTAMGFPDEMCMLGTVGIPAVYNEIRLEEVAEMGYDPL 203
F+ V CC + QGYGLTE+ G GT D G VG P + EI+L++ E GY
Sbjct: 412 FMNVCFCCPIGQGYGLTESCGAGTVTEVTD--YTTGRVGAPLICCEIKLKDWQEGGYTVH 469
Query: 204 GE-NPAGEICIRGKCLFSGYYKNPELTQE---VMKDG--WFHTGDIGEIQSNGVLKIIDR 365
+ NP GEI I G+ + GY+KN E T E V ++G WF TGDIGE +G L+IIDR
Sbjct: 470 DKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDR 529
Query: 366 KKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAKEL 545
KK+L+KL GEYV+L +E L+ +I + S +S +++ +VPNQ+ + A++
Sbjct: 530 KKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLAQQK 589
Query: 546 GFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTATLK 725
G + ++C+ ++ I+ E++ A KL +FE V + +P+ LVT K
Sbjct: 590 GVEGSWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFK 649
Query: 726 NRRNNLLKYYQVHVEEMY 779
+R L +Y +E MY
Sbjct: 650 LKRKELKNHYLKDIERMY 667
>sp|O60488|ACSL4_HUMAN Long-chain-fatty-acid--CoA ligase 4 OS=Homo sapiens
GN=ACSL4 PE=1 SV=2
Length = 711
Score = 156 bits (392), Expect = 4e-037
Identities = 96/258 (37%), Positives = 143/258 (55%), Gaps = 9/258 (3%)
Frame = +3
Query: 27 FLRVTCCCFVVQGYGLTETLG-GTAMGFPDEMCMLGTVGIPAVYNEIRLEEVAEMGYDPL 203
F+ V CC + QGYGLTE+ G GT D G VG P + EI+L++ E GY
Sbjct: 453 FMNVCFCCPIGQGYGLTESCGAGTVTEVTD--YTTGRVGAPLICCEIKLKDWQEGGYTIN 510
Query: 204 GE-NPAGEICIRGKCLFSGYYKNPELTQE---VMKDG--WFHTGDIGEIQSNGVLKIIDR 365
+ NP GEI I G+ + GY+KN E T E V ++G WF TGDIGE +G L+IIDR
Sbjct: 511 DKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDR 570
Query: 366 KKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAKEL 545
KK+L+KL GEYV+L +E L+ +I + S +S +++ +VPNQ+ + A++
Sbjct: 571 KKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQK 630
Query: 546 GFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTATLK 725
G + ++C+ ++ I+ E++ A KL +FE V + +P+ LVT K
Sbjct: 631 GVEGTWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFK 690
Query: 726 NRRNNLLKYYQVHVEEMY 779
+R L +Y +E MY
Sbjct: 691 LKRKELRNHYLKDIERMY 708
>sp|Q9QUJ7|ACSL4_MOUSE Long-chain-fatty-acid--CoA ligase 4 OS=Mus musculus
GN=Acsl4 PE=2 SV=1
Length = 711
Score = 156 bits (392), Expect = 4e-037
Identities = 97/258 (37%), Positives = 142/258 (55%), Gaps = 9/258 (3%)
Frame = +3
Query: 27 FLRVTCCCFVVQGYGLTETLG-GTAMGFPDEMCMLGTVGIPAVYNEIRLEEVAEMGYDPL 203
F+ V CC + QGYGLTE+ G GT D G VG P + EI+L++ E GY
Sbjct: 453 FMNVCLCCPIGQGYGLTESCGAGTVTEVTD--YTTGRVGAPLICCEIKLKDWQEGGYTVH 510
Query: 204 GE-NPAGEICIRGKCLFSGYYKNPELTQE---VMKDG--WFHTGDIGEIQSNGVLKIIDR 365
+ NP GEI I G+ + GY+KN E T E V ++G WF TGDIGE +G L+IIDR
Sbjct: 511 DKPNPRGEIVIGGQNISMGYFKNEEKTAEDYCVDENGQRWFCTGDIGEFHPDGCLQIIDR 570
Query: 366 KKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAKEL 545
KK+L+KL GEYV L +E L+ +I + S +S +++ +VPNQ+ + A++
Sbjct: 571 KKDLVKLQAGEYVFLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLAQQK 630
Query: 546 GFTKPFEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVTATLK 725
G + ++C+ ++ I+ E++ A KL +FE V + +P+ LVT K
Sbjct: 631 GVEGSWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFK 690
Query: 726 NRRNNLLKYYQVHVEEMY 779
+R L +Y VE MY
Sbjct: 691 LKRKELKNHYLKDVERMY 708
>sp|O60135|LCF1_SCHPO Long-chain-fatty-acid--CoA ligase 1 OS=Schizosaccharomyces
pombe GN=lcf1 PE=2 SV=1
Length = 676
Score = 150 bits (378), Expect = 2e-035
Identities = 90/262 (34%), Positives = 137/262 (52%), Gaps = 5/262 (1%)
Frame = +3
Query: 6 LSTEIEEFLRVTCCCFVVQGYGLTETLGGTAMGFPDEMCMLGTVGIPAVYNEIRLEEVAE 185
LS + + FL + C ++ GYGLTE + P + + G E++L + E
Sbjct: 414 LSPDTKRFLSIVLCPMLI-GYGLTEISAAAMVQNPACFNLDDSAGSLLPCTEMKLVDCEE 472
Query: 186 MGYDPLGENPAGEICIRGKCLFSGYY-KNPELTQEVMKDGWFHTGDIGEIQSNGVLKIID 362
Y+ G P GEI +RG L GY ++ E + DGWF TGD+GE+ G+L+IID
Sbjct: 473 GNYNSHGHPPRGEIWLRGPSLTRGYLNRDKENKESFTPDGWFRTGDVGELTPEGLLRIID 532
Query: 363 RKKNLIKLSQGEYVALENLENIYGQNSLVQDIWVYGDSFKSMLVAVIVPNQETVKRWAKE 542
RKKNL+K GEY+ALE LE+ Y +SLV +I VY D K +A+IVPN+ V++ A E
Sbjct: 533 RKKNLVKTQNGEYIALEKLESRYRTSSLVSNICVYADQTKVKPLAIIVPNEPVVRKLATE 592
Query: 543 LGFTKP---FEELCSLSELQEHIISELKSTAEKNKLRKFEYIKAVTVETKPFDVARDLVT 713
P +EE+C ++++ + +L + E I+ V + F LVT
Sbjct: 593 QAGLSPDASWEEVCHNKKVRQLVYDDLIRIGRSHHFANIELIQNVVLVPIEFTPENGLVT 652
Query: 714 ATLKNRRNNLLKYYQVHVEEMY 779
A K +R +L ++ ++ Y
Sbjct: 653 AAQKLQRRKILDRFKKEIDAAY 674
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,311,517,917
Number of Sequences: 518415
Number of Extensions: 63311517917
Number of Successful Extensions: 429036050
Number of sequences better than 0.0: 0
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