BLASTX 7.6.2
Query= UN15830 /QuerySize=1047
(1046 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9R0M5|TPK1_MOUSE Thiamin pyrophosphokinase 1 OS=Mus musculus... 132 5e-030
sp|Q9H3S4|TPK1_HUMAN Thiamin pyrophosphokinase 1 OS=Homo sapiens... 131 1e-029
sp|Q5E9T4|TPK1_BOVIN Thiamin pyrophosphokinase 1 OS=Bos taurus G... 129 4e-029
sp|P41888|TNR3_SCHPO Thiamine pyrophosphokinase OS=Schizosacchar... 94 1e-018
sp|P30636|TPK1_CAEEL Thiamin pyrophosphokinase 1 OS=Caenorhabdit... 80 3e-014
sp|P35202|THI80_YEAST Thiamine pyrophosphokinase OS=Saccharomyce... 63 4e-009
>sp|Q9R0M5|TPK1_MOUSE Thiamin pyrophosphokinase 1 OS=Mus musculus GN=Tpk1 PE=1
SV=1
Length = 243
Score = 132 bits (331), Expect = 5e-030
Identities = 73/185 (39%), Positives = 107/185 (57%), Gaps = 6/185 (3%)
Frame = +3
Query: 285 RNRYKPDVIKGDMDSIRPDVLRFYLSLGTKVIDESHDQDTTDLDKCILYIRDSTLNQESS 464
R + P+ + GD DSIRP+V +Y G +I + DQD TD KC+ ++ +E
Sbjct: 60 RESFLPEFVSGDFDSIRPEVKEYYTKKGCDLI-STPDQDHTDFTKCLQVLQRKIEEKELQ 118
Query: 465 RLQILATGALGGRFDHEAGNLNVLYR---YPDTRIIFLSDDCLIQLLPKTHRHEIQIQPS 635
I+ G LGGRFD ++N L++ II + D LI LL + +H + +
Sbjct: 119 VDVIVTLGGLGGRFDQIMASVNTLFQATHITPVPIIIIQKDSLIYLL-QPGKHRLHVDTG 177
Query: 636 LQGPHCGLIPMGTPSAKTTTTGLQWDLTDTEMRFGGLISTSNKVKGE-KITVESDSDLLW 812
++G CGLIP+G P + TTTGL+W+LT+ + FG L+STSN G +TVE+D LLW
Sbjct: 178 MEGSWCGLIPVGQPCNQVTTTGLKWNLTNDVLGFGTLVSTSNTYDGSGLVTVETDHPLLW 237
Query: 813 TISIK 827
T++IK
Sbjct: 238 TMAIK 242
>sp|Q9H3S4|TPK1_HUMAN Thiamin pyrophosphokinase 1 OS=Homo sapiens GN=TPK1 PE=2
SV=1
Length = 243
Score = 131 bits (327), Expect = 1e-029
Identities = 71/185 (38%), Positives = 109/185 (58%), Gaps = 6/185 (3%)
Frame = +3
Query: 285 RNRYKPDVIKGDMDSIRPDVLRFYLSLGTKVIDESHDQDTTDLDKCILYIRDSTLNQESS 464
R + P+ I GD DSIRP+V +Y + G ++I + DQD TD KC+ ++ ++
Sbjct: 60 RESFLPEFINGDFDSIRPEVREYYATKGCELI-STPDQDHTDFTKCLKMLQKKIEEKDLK 118
Query: 465 RLQILATGALGGRFDHEAGNLNVLYRYPDTR---IIFLSDDCLIQLLPKTHRHEIQIQPS 635
I+ G L GRFD ++N L++ II + ++ LI LL + +H + +
Sbjct: 119 VDVIVTLGGLAGRFDQIMASVNTLFQATHITPFPIIIIQEESLIYLL-QPGKHRLHVDTG 177
Query: 636 LQGPHCGLIPMGTPSAKTTTTGLQWDLTDTEMRFGGLISTSNKVKGE-KITVESDSDLLW 812
++G CGLIP+G P + TTTGL+W+LT+ + FG L+STSN G +TVE+D LLW
Sbjct: 178 MEGDWCGLIPVGQPCMQVTTTGLKWNLTNDVLAFGTLVSTSNTYDGSGVVTVETDHPLLW 237
Query: 813 TISIK 827
T++IK
Sbjct: 238 TMAIK 242
>sp|Q5E9T4|TPK1_BOVIN Thiamin pyrophosphokinase 1 OS=Bos taurus GN=TPK1 PE=2
SV=1
Length = 243
Score = 129 bits (323), Expect = 4e-029
Identities = 70/185 (37%), Positives = 108/185 (58%), Gaps = 6/185 (3%)
Frame = +3
Query: 285 RNRYKPDVIKGDMDSIRPDVLRFYLSLGTKVIDESHDQDTTDLDKCILYIRDSTLNQESS 464
R + P+ I GD DSIRP+V Y G ++I + DQD TD KC+ ++ ++
Sbjct: 60 RESFLPEFISGDFDSIRPEVREHYAIKGCEII-STPDQDHTDFTKCLEVLQKKIEEKDLQ 118
Query: 465 RLQILATGALGGRFDHEAGNLNVLYRYPDTR---IIFLSDDCLIQLLPKTHRHEIQIQPS 635
I+ G L GRFD +++ L++ P +I + ++ LI LL + +H++ +
Sbjct: 119 VDMIVTLGGLAGRFDQIMASVSTLFQAPQITSLPVIIIQEESLIYLL-QPGKHKLHVDTG 177
Query: 636 LQGPHCGLIPMGTPSAKTTTTGLQWDLTDTEMRFGGLISTSNKVKGE-KITVESDSDLLW 812
++G CGLIP+G P + TTTGL+W+LT + FG L+STSN G +TVE+D LLW
Sbjct: 178 MEGDWCGLIPVGQPCNQVTTTGLKWNLTHQMLGFGTLVSTSNTYDGSGVVTVETDHPLLW 237
Query: 813 TISIK 827
T++IK
Sbjct: 238 TMAIK 242
>sp|P41888|TNR3_SCHPO Thiamine pyrophosphokinase OS=Schizosaccharomyces pombe
GN=tnr3 PE=2 SV=1
Length = 569
Score = 94 bits (232), Expect = 1e-018
Identities = 53/180 (29%), Positives = 94/180 (52%), Gaps = 11/180 (6%)
Frame = +3
Query: 297 KPDVIKGDMDSIRPDVLRFYLSLGTKVIDESHDQDTTDLDKCILYIRDSTLNQESSRLQI 476
KPD + GD DS+ + +Y +G ++ + Q+TTD KC I++ ++ I
Sbjct: 397 KPDYVVGDFDSLTDETKAYYKEMGVNIVFDP-CQNTTDFMKCHKIIKEHGID------TI 449
Query: 477 LATGALGGRFDHEAGNLNVLY---RYPDTRIIFLSDDCLIQLLPKTHRHEIQIQPSLQGP 647
+GGR DH GNLN L+ + +FL + + L + + + ++ G
Sbjct: 450 FVLCGMGGRVDHAIGNLNHLFWAASISEKNEVFLLTELNVSTLLQPGINHVDCHDNI-GL 508
Query: 648 HCGLIPMGTPSAKTTTTGLQWDLTDTEMRFGGLISTSNKVKGEKITVESDSDLLWTISIK 827
HCGL+P+G T+GL+W++ D +FGGL+S+ N V +T+E ++ ++WT+ +
Sbjct: 509 HCGLLPVGQSVYVKKTSGLEWNIEDRICQFGGLVSSCNVVTKATVTIEVNNFIVWTMETR 568
>sp|P30636|TPK1_CAEEL Thiamin pyrophosphokinase 1 OS=Caenorhabditis elegans
GN=tpk-1 PE=1 SV=3
Length = 243
Score = 80 bits (195), Expect = 3e-014
Identities = 54/180 (30%), Positives = 88/180 (48%), Gaps = 12/180 (6%)
Frame = +3
Query: 300 PDVIKGDMDSIRPDVLRFYLSLGTKVIDESH--DQDTTDLDKCILYIRDSTLNQESSRLQ 473
P +I GD DSI + TK H DQD TDL K + + +
Sbjct: 63 PHIICGDFDSINKQI-------DTKNAKVVHLPDQDYTDLSKSVQWCLEQKTLTSWEFEN 115
Query: 474 ILATGALGGRFDHEAGNLNVLYRYPD--TRIIFLSDDCLIQLLPKTHRHEIQIQPSLQGP 647
I+ G L GRFDH L+ L R+ D T +I L L+ +P T + + +
Sbjct: 116 IVVLGGLNGRFDHTMSTLSSLIRFVDSQTPVIVLDSRNLVLAVP-TGDSNLDVNLEMTTK 174
Query: 648 HCGLIPMGTPSAKTTTTGLQWDLTDTEMRFGGLISTSNKVKGEKITVESDSDLLWTISIK 827
CG+IP+ ++ GL++++ + + FG LISTSN+V ++ ++S S L+++I ++
Sbjct: 175 MCGIIPIVQKETIVSSIGLKYEMENLALEFGKLISTSNEVTTSQVFLKSSSSLIFSIELE 234
>sp|P35202|THI80_YEAST Thiamine pyrophosphokinase OS=Saccharomyces cerevisiae
GN=THI80 PE=1 SV=1
Length = 319
Score = 63 bits (151), Expect = 4e-009
Identities = 38/108 (35%), Positives = 60/108 (55%), Gaps = 10/108 (9%)
Frame = +3
Query: 111 IPADEASAYAVVVLNQKLPRFTPL---LWEHAKLRLCADGGANRIYDELPLFFPHDDALL 281
I +E +++LNQK+ PL +W+ L++CADG ANR+YD L DD
Sbjct: 31 IHPNEDENSTLLILNQKIDIPRPLFYKIWKLHDLKVCADGAANRLYDYL------DDDET 84
Query: 282 VRNRYKPDVIKGDMDSIRPDVLRFYLSLGTKVIDESHDQDTTDLDKCI 425
+R +Y P+ I GD+DS+ V ++Y +I ++ Q +TD KC+
Sbjct: 85 LRIKYLPNYIIGDLDSLSEKVYKYYRKNKVTIIKQT-TQYSTDFTKCV 131
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,834,329,955
Number of Sequences: 518415
Number of Extensions: 63834329955
Number of Successful Extensions: 437743986
Number of sequences better than 0.0: 0
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