BLASTX 7.6.2
Query= UN16068 /QuerySize=1058
(1057 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8RWG8|RBP1B_ARATH Ran-binding protein 1 homolog b OS=Arabido... 234 9e-061
sp|Q9LMK7|RBP1A_ARATH Ran-binding protein 1 homolog a OS=Arabido... 216 3e-055
sp|P92985|RBP1C_ARATH Ran-binding protein 1 homolog c OS=Arabido... 198 7e-050
sp|Q3T0M7|RANG_BOVIN Ran-specific GTPase-activating protein OS=B... 98 1e-019
sp|Q09717|RANG_SCHPO Ran-specific GTPase-activating protein 1 OS... 89 5e-017
sp|P49792|RBP2_HUMAN E3 SUMO-protein ligase RanBP2 OS=Homo sapie... 81 1e-014
sp|Q9ERU9|RBP2_MOUSE E3 SUMO-protein ligase RanBP2 OS=Mus muscul... 81 1e-014
sp|A6NKT7|RGPD3_HUMAN RanBP2-like and GRIP domain-containing pro... 77 2e-013
sp|Q99666|RGPD5_HUMAN RANBP2-like and GRIP domain-containing pro... 77 2e-013
sp|O14715|RGPD8_HUMAN RANBP2-like and GRIP domain-containing pro... 77 2e-013
sp|Q7Z3J3|RGPD4_HUMAN RanBP2-like and GRIP domain-containing pro... 75 5e-013
sp|Q68DN6|RGPD1_HUMAN RANBP2-like and GRIP domain-containing pro... 74 2e-012
>sp|Q8RWG8|RBP1B_ARATH Ran-binding protein 1 homolog b OS=Arabidopsis thaliana
GN=RANBP1B PE=1 SV=2
Length = 217
Score = 234 bits (596), Expect = 9e-061
Identities = 124/160 (77%), Positives = 133/160 (83%), Gaps = 11/160 (6%)
Frame = +3
Query: 285 KMGVSGRREVLGLSSSLKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCV 464
K G + G LKH+ +GKIRLVMRQSKTLKICANHLV SGMSVQEHAGNDKSCV
Sbjct: 63 KDGSQWKERGAGTVKFLKHRVSGKIRLVMRQSKTLKICANHLVGSGMSVQEHAGNDKSCV 122
Query: 465 WHARDFSDGELKDELFCIRFANVENCKAFMQKFKEVAESEEEKEESKDASEAAGLLEKLT 644
WHARDFSDGELKDELFCIRFA+VENCKAFMQKFKEVAESEEEKEESKDAS+ AGLLEKLT
Sbjct: 123 WHARDFSDGELKDELFCIRFASVENCKAFMQKFKEVAESEEEKEESKDASDTAGLLEKLT 182
Query: 645 VEEKHTEEEEKKEEKPVEKAE-----KAVEEKKTEETVPS 749
VEEK + E+KPVEKAE +AVEEKKTEE+VPS
Sbjct: 183 VEEK------ESEKKPVEKAEENKKSEAVEEKKTEESVPS 216
Score = 153 bits (386), Expect = 2e-036
Identities = 74/80 (92%), Positives = 80/80 (100%)
Frame = +2
Query: 98 MASISNEPEREHRDEEESGANEDEDTGAQVAPIIKLEEVAVTTGEENEDTILDLKSKLYR 277
MASISNEPERE+RDEEE+GANEDEDTGAQVAPI++LEEVAVTTGEE+EDTILDLKSKLYR
Sbjct: 1 MASISNEPERENRDEEETGANEDEDTGAQVAPIVRLEEVAVTTGEEDEDTILDLKSKLYR 60
Query: 278 FDKDGSQWKERGAGTVKFLE 337
FDKDGSQWKERGAGTVKFL+
Sbjct: 61 FDKDGSQWKERGAGTVKFLK 80
>sp|Q9LMK7|RBP1A_ARATH Ran-binding protein 1 homolog a OS=Arabidopsis thaliana
GN=RANBP1A PE=1 SV=1
Length = 228
Score = 216 bits (549), Expect = 3e-055
Identities = 112/146 (76%), Positives = 119/146 (81%), Gaps = 4/146 (2%)
Frame = +3
Query: 318 GLSSSLKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGEL 497
G LKHK TGKIRLVMRQSKTLKICANH V SGMSVQEH GN+KSCVWHARDF+DGEL
Sbjct: 72 GTVKFLKHKNTGKIRLVMRQSKTLKICANHFVKSGMSVQEHVGNEKSCVWHARDFADGEL 131
Query: 498 KDELFCIRFANVENCKAFMQKFKEVAESEEEKEESKDASEAAGLLEKLTVEEKHTEEEEK 677
KDELFCIRFA++ENCK FMQKFKEVAESEEEKEESKDA++ AGLLEKLTVEE T+ EEK
Sbjct: 132 KDELFCIRFASIENCKTFMQKFKEVAESEEEKEESKDAADTAGLLEKLTVEE--TKTEEK 189
Query: 678 KEEKPVE--KAEKAVEEKKTEETVPS 749
E K VE K E EEKK E S
Sbjct: 190 TEAKAVETAKTEVKAEEKKESEAEKS 215
Score = 141 bits (353), Expect = 1e-032
Identities = 65/76 (85%), Positives = 73/76 (96%)
Frame = +2
Query: 110 SNEPEREHRDEEESGANEDEDTGAQVAPIIKLEEVAVTTGEENEDTILDLKSKLYRFDKD 289
+NEPE EHRDEEE+GANEDEDTGAQVAPI++LEEVAVTTGEE+ED +LDLKSKLYRFDKD
Sbjct: 3 TNEPEHEHRDEEEAGANEDEDTGAQVAPIVRLEEVAVTTGEEDEDAVLDLKSKLYRFDKD 62
Query: 290 GSQWKERGAGTVKFLE 337
+QWKERGAGTVKFL+
Sbjct: 63 ANQWKERGAGTVKFLK 78
>sp|P92985|RBP1C_ARATH Ran-binding protein 1 homolog c OS=Arabidopsis thaliana
GN=RANBP1C PE=2 SV=1
Length = 219
Score = 198 bits (502), Expect = 7e-050
Identities = 99/157 (63%), Positives = 117/157 (74%), Gaps = 7/157 (4%)
Frame = +3
Query: 285 KMGVSGRREVLGLSSSLKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCV 464
K G + G LKHKETGK+RLVMRQSKTLKICANHL++SGMSVQEH+GN+KSC+
Sbjct: 60 KEGNQWKERGAGTVKLLKHKETGKVRLVMRQSKTLKICANHLISSGMSVQEHSGNEKSCL 119
Query: 465 WHARDFSDGELKDELFCIRFANVENCKAFMQKFKEVAESEEEKEESKDASEAAGLLEKLT 644
WHA DFSDGELKDELFCIRFA++ENCK FM+KF E+AES++ +ES EAAGL+E L+
Sbjct: 120 WHATDFSDGELKDELFCIRFASIENCKTFMEKFTEIAESQQVGKESTQGDEAAGLIENLS 179
Query: 645 VEE-------KHTEEEEKKEEKPVEKAEKAVEEKKTE 734
VEE K EE+E +E K EK EEKKTE
Sbjct: 180 VEENISEEKAKEAEEKEPAKEDKETKKEKVEEEKKTE 216
Score = 124 bits (309), Expect = 2e-027
Identities = 59/76 (77%), Positives = 70/76 (92%), Gaps = 1/76 (1%)
Frame = +2
Query: 110 SNEPEREHRDEEESGANEDEDTGAQVAPIIKLEEVAVTTGEENEDTILDLKSKLYRFDKD 289
S EPERE+R E+E+ NEDEDTGAQVAPI++LEEVAVTTGEE+ED +LDLKSK+YRFDK+
Sbjct: 3 STEPERENR-EDETEVNEDEDTGAQVAPIVRLEEVAVTTGEEDEDAVLDLKSKMYRFDKE 61
Query: 290 GSQWKERGAGTVKFLE 337
G+QWKERGAGTVK L+
Sbjct: 62 GNQWKERGAGTVKLLK 77
>sp|Q3T0M7|RANG_BOVIN Ran-specific GTPase-activating protein OS=Bos taurus
GN=RANBP1 PE=2 SV=1
Length = 206
Score = 98 bits (242), Expect = 1e-019
Identities = 60/130 (46%), Positives = 78/130 (60%), Gaps = 5/130 (3%)
Frame = +3
Query: 333 LKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHAR-DFSDGELKDEL 509
LKHKE G IRL+MR+ KTLKICANH +T M ++ +AG+D++ VW+ DF+D K EL
Sbjct: 78 LKHKEKGTIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAWVWNTHADFADECPKQEL 137
Query: 510 FCIRFANVENCKAFMQKFKEVAESEEEKEESKDASEAAGLLEKLTVEEKHTEEEEKKEEK 689
IRF N EN + F KF+E + EEKE K S EK V EK ++ E+
Sbjct: 138 LAIRFLNAENAQKFKTKFEECRKEIEEKE--KKGSGKNDSTEK--VVEKLEALSVQEGEQ 193
Query: 690 PVEKAEKAVE 719
P + A AVE
Sbjct: 194 PQDAAPAAVE 203
>sp|Q09717|RANG_SCHPO Ran-specific GTPase-activating protein 1
OS=Schizosaccharomyces pombe GN=sbp1 PE=1 SV=1
Length = 215
Score = 89 bits (219), Expect = 5e-017
Identities = 45/83 (54%), Positives = 56/83 (67%), Gaps = 1/83 (1%)
Frame = +3
Query: 333 LKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWH-ARDFSDGELKDEL 509
LKHKETGK RLVMR+ KTLK+CANHL+ M + + G+D+S VW A D S+GE E
Sbjct: 124 LKHKETGKTRLVMRRDKTLKVCANHLLMPEMKLTPNVGSDRSWVWTVAADVSEGEPTAET 183
Query: 510 FCIRFANVENCKAFMQKFKEVAE 578
F IRFAN EN F + F++ E
Sbjct: 184 FAIRFANSENANLFKENFEKYQE 206
>sp|P49792|RBP2_HUMAN E3 SUMO-protein ligase RanBP2 OS=Homo sapiens GN=RANBP2
PE=1 SV=2
Length = 3224
Score = 81 bits (198), Expect = 1e-014
Identities = 39/85 (45%), Positives = 54/85 (63%)
Frame = +3
Query: 315 LGLSSSLKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGE 494
+G L+HK +GKIRL+MR+ + LKICANH ++ M + +AG+D+S VWHA D++D
Sbjct: 1216 IGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAGSDRSFVWHALDYADEL 1275
Query: 495 LKDELFCIRFANVENCKAFMQKFKE 569
K E IRF E F KF+E
Sbjct: 1276 PKPEQLAIRFKTPEEAALFKCKFEE 1300
Score = 76 bits (186), Expect = 3e-013
Identities = 35/85 (41%), Positives = 57/85 (67%)
Frame = +3
Query: 315 LGLSSSLKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGE 494
LG LK++ GK+R++MR+ + LK+CANH +T+ M+++ +G+D++ +W A DFSDG+
Sbjct: 2057 LGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGD 2116
Query: 495 LKDELFCIRFANVENCKAFMQKFKE 569
K E +F E + F QKF+E
Sbjct: 2117 AKLEQLAAKFKTPELAEEFKQKFEE 2141
>sp|Q9ERU9|RBP2_MOUSE E3 SUMO-protein ligase RanBP2 OS=Mus musculus GN=Ranbp2
PE=1 SV=1
Length = 3053
Score = 81 bits (198), Expect = 1e-014
Identities = 39/85 (45%), Positives = 54/85 (63%)
Frame = +3
Query: 315 LGLSSSLKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGE 494
+G L+HK +GKIRL+MR+ + LKICANH ++ M + +AG+D+S VWHA D++D
Sbjct: 1210 IGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAGSDRSFVWHALDYADEL 1269
Query: 495 LKDELFCIRFANVENCKAFMQKFKE 569
K E IRF E F KF+E
Sbjct: 1270 PKPEQLAIRFKTPEEAALFKCKFEE 1294
Score = 76 bits (186), Expect = 3e-013
Identities = 35/85 (41%), Positives = 57/85 (67%)
Frame = +3
Query: 315 LGLSSSLKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGE 494
LG LK++ GK+R++MR+ + LK+CANH +T+ M+++ +G+D++ +W A DFSDG+
Sbjct: 1894 LGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGD 1953
Query: 495 LKDELFCIRFANVENCKAFMQKFKE 569
K E +F E + F QKF+E
Sbjct: 1954 AKLEQLAAKFKTPELAEEFKQKFEE 1978
>sp|A6NKT7|RGPD3_HUMAN RanBP2-like and GRIP domain-containing protein 3 OS=Homo
sapiens GN=RGPD3 PE=2 SV=1
Length = 1766
Score = 77 bits (188), Expect = 2e-013
Identities = 46/147 (31%), Positives = 80/147 (54%), Gaps = 7/147 (4%)
Frame = +3
Query: 315 LGLSSSLKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGE 494
LG LK++ GK+R++M++ + LK+CANH +T+ M+++ +G+D++ +W A DFSDG+
Sbjct: 1082 LGNLKILKNEVNGKVRMLMQREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGD 1141
Query: 495 LKDELFCIRFANVENCKAFMQKFKEVAE-----SEEEKEESKDASEAAGLLEKLTVEEKH 659
K E +F E + F QKF+E + + D AA L+++ EE
Sbjct: 1142 AKLERLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQR--AEEMK 1199
Query: 660 TEEEEKKEEKPVEKAEKAVEEKKTEET 740
+ ++ K ++ + A EE K T
Sbjct: 1200 SGLKDFKTFLTNDQTKVAEEENKGSGT 1226
>sp|Q99666|RGPD5_HUMAN RANBP2-like and GRIP domain-containing protein 5/6
OS=Homo sapiens GN=RGPD5 PE=1 SV=3
Length = 1765
Score = 77 bits (188), Expect = 2e-013
Identities = 35/85 (41%), Positives = 57/85 (67%)
Frame = +3
Query: 315 LGLSSSLKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGE 494
LG LK++ GK+R++MR+ + LK+CANH +T+ M+++ +G+D++ +W A DFSDG+
Sbjct: 1081 LGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGD 1140
Query: 495 LKDELFCIRFANVENCKAFMQKFKE 569
K E +F E + F QKF+E
Sbjct: 1141 AKLERLAAKFKTPELAEEFKQKFEE 1165
Score = 68 bits (164), Expect = 1e-010
Identities = 32/86 (37%), Positives = 53/86 (61%)
Frame = +3
Query: 333 LKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGELKDELF 512
L++ + ++R+VMR+ + LK+CANH +T MS+Q G ++ VW A DF+DGE K E
Sbjct: 1384 LQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHL 1443
Query: 513 CIRFANVENCKAFMQKFKEVAESEEE 590
+RF + +F + F E ++E+
Sbjct: 1444 AVRFKLQDVADSFKKIFDEAKTAQEK 1469
>sp|O14715|RGPD8_HUMAN RANBP2-like and GRIP domain-containing protein 8 OS=Homo
sapiens GN=RGPD8 PE=1 SV=2
Length = 1765
Score = 77 bits (188), Expect = 2e-013
Identities = 35/85 (41%), Positives = 57/85 (67%)
Frame = +3
Query: 315 LGLSSSLKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGE 494
LG LK++ GK+R++MR+ + LK+CANH +T+ M+++ +G+D++ +W A DFSDG+
Sbjct: 1081 LGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGD 1140
Query: 495 LKDELFCIRFANVENCKAFMQKFKE 569
K E +F E + F QKF+E
Sbjct: 1141 AKLERLAAKFKTPELAEEFKQKFEE 1165
>sp|Q7Z3J3|RGPD4_HUMAN RanBP2-like and GRIP domain-containing protein 4 OS=Homo
sapiens GN=RGPD4 PE=2 SV=2
Length = 1766
Score = 75 bits (184), Expect = 5e-013
Identities = 46/147 (31%), Positives = 79/147 (53%), Gaps = 7/147 (4%)
Frame = +3
Query: 315 LGLSSSLKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGE 494
LG LK++ GK R++MR+ + LK+CANH +T+ M+++ +G+D++ +W A DFSDG+
Sbjct: 1082 LGNLKILKNEVNGKPRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGD 1141
Query: 495 LKDELFCIRFANVENCKAFMQKFKEVAE-----SEEEKEESKDASEAAGLLEKLTVEEKH 659
K E +F E + F QKF+E + + + D AA L+++ EE
Sbjct: 1142 AKLERLAAKFKTPELAEEFKQKFEECQQLLLDIPLQTPHKLVDTGRAAKLIQR--AEEMK 1199
Query: 660 TEEEEKKEEKPVEKAEKAVEEKKTEET 740
+ ++ K ++ + EE K T
Sbjct: 1200 SGLKDFKTFLTNDQTKVTEEENKGSGT 1226
Score = 68 bits (165), Expect = 9e-011
Identities = 32/86 (37%), Positives = 53/86 (61%)
Frame = +3
Query: 333 LKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGELKDELF 512
L++ + ++R+VMR+ + LK+CANH +T MS+Q G ++ VW A DF+DGE K E
Sbjct: 1385 LQNYDNKQVRIVMRRDQVLKLCANHTITPDMSLQNMKGTERVWVWTACDFADGERKVEHL 1444
Query: 513 CIRFANVENCKAFMQKFKEVAESEEE 590
+RF + +F + F E ++E+
Sbjct: 1445 AVRFKLQDVADSFKKIFDEAKTAQEK 1470
>sp|Q68DN6|RGPD1_HUMAN RANBP2-like and GRIP domain-containing protein 1/2
OS=Homo sapiens GN=RGPD1 PE=1 SV=2
Length = 1748
Score = 74 bits (180), Expect = 2e-012
Identities = 35/85 (41%), Positives = 56/85 (65%)
Frame = +3
Query: 315 LGLSSSLKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGE 494
LG LK++ GK R++MR+ + LK+CANH +T+ M+++ +G+D++ +W A DFSDG+
Sbjct: 1066 LGNLKILKNEVNGKPRMLMRRDQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGD 1125
Query: 495 LKDELFCIRFANVENCKAFMQKFKE 569
K E +F E + F QKF+E
Sbjct: 1126 AKLERLAAQFKTPELAEEFKQKFEE 1150
Score = 68 bits (164), Expect = 1e-010
Identities = 32/86 (37%), Positives = 53/86 (61%)
Frame = +3
Query: 333 LKHKETGKIRLVMRQSKTLKICANHLVTSGMSVQEHAGNDKSCVWHARDFSDGELKDELF 512
L++ + ++R+VMR+ + LK+CANH +T MS+Q G ++ VW A DF+DGE K E
Sbjct: 1369 LQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHL 1428
Query: 513 CIRFANVENCKAFMQKFKEVAESEEE 590
+RF + +F + F E ++E+
Sbjct: 1429 AVRFKLQDVADSFKKIFDEAKTAQEK 1454
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,889,068,748
Number of Sequences: 518415
Number of Extensions: 64889068748
Number of Successful Extensions: 459589147
Number of sequences better than 0.0: 0
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