BLASTX 7.6.2
Query= UN16091 /QuerySize=1300
(1299 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q40345|IDHP_MEDSA Isocitrate dehydrogenase [NADP], chloroplas... 510 1e-143
sp|Q06197|IDHC_SOYBN Isocitrate dehydrogenase [NADP] OS=Glycine ... 509 3e-143
sp|P50218|IDHC_TOBAC Isocitrate dehydrogenase [NADP] OS=Nicotian... 507 7e-143
sp|P50217|IDHC_SOLTU Isocitrate dehydrogenase [NADP] OS=Solanum ... 503 1e-141
sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytoplasmic... 389 3e-107
sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytoplasmic... 388 6e-107
sp|P41562|IDHC_RAT Isocitrate dehydrogenase [NADP] cytoplasmic O... 387 1e-106
sp|Q9XSG3|IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytoplasmic... 386 2e-106
sp|Q6XUZ5|IDHC_SHEEP Isocitrate dehydrogenase [NADP] cytoplasmic... 386 2e-106
sp|Q5R9C5|IDHC_PONAB Isocitrate dehydrogenase [NADP] cytoplasmic... 382 4e-105
sp|O75874|IDHC_HUMAN Isocitrate dehydrogenase [NADP] cytoplasmic... 382 5e-105
sp|O88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytoplasmic... 382 5e-105
sp|P33198|IDHP_PIG Isocitrate dehydrogenase [NADP], mitochondria... 369 4e-101
sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitochondr... 368 5e-101
sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitochondr... 367 9e-101
sp|P48735|IDHP_HUMAN Isocitrate dehydrogenase [NADP], mitochondr... 367 9e-101
sp|Q4R502|IDHP_MACFA Isocitrate dehydrogenase [NADP], mitochondr... 367 9e-101
sp|P56574|IDHP_RAT Isocitrate dehydrogenase [NADP], mitochondria... 367 2e-100
sp|O14254|IDHP_SCHPO Probable isocitrate dehydrogenase [NADP], m... 357 2e-097
sp|O13285|IDH1_CANTR Isocitrate dehydrogenase [NADP], mitochondr... 347 1e-094
>sp|Q40345|IDHP_MEDSA Isocitrate dehydrogenase [NADP], chloroplastic (Fragment)
OS=Medicago sativa PE=2 SV=1
Length = 433
Score = 510 bits (1311), Expect = 1e-143
Identities = 248/283 (87%), Positives = 265/283 (93%), Gaps = 2/283 (0%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTF--EGKDGKTETEVFTFTGEGGVAMAMYNTDE 871
ICIGRHAFGDQYRATD+VIKGPG+L + F EG+ T+ EV+ FTGEGGVA+AMYNTDE
Sbjct: 151 ICIGRHAFGDQYRATDSVIKGPGKLKLVFVPEGQGETTDLEVYNFTGEGGVALAMYNTDE 210
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SIR+FA+ASM A EKKWPLYLSTKNTILKKYDGRFKDIFQEVYEA WKSKYEAAGIWYE
Sbjct: 211 SIRSFAEASMAVALEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEAGWKSKYEAAGIWYE 270
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA
Sbjct: 271 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 330
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRH+RVHQKGGETSTNSIASIFAWTRGLAHRAKLDDN+ LL+FTEKLEAAC+G V
Sbjct: 331 AHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNATLLDFTEKLEAACIGVV 390
Query: 330 ESGKMTKDLALIIHGSKLSRDTYLNTEEFIDAVAEELKTRLGA 202
ESGKMTKDLALI+HGSKLSR+ YLNTEEFIDAVA ELKT++ A
Sbjct: 391 ESGKMTKDLALILHGSKLSREHYLNTEEFIDAVAAELKTKISA 433
>sp|Q06197|IDHC_SOYBN Isocitrate dehydrogenase [NADP] OS=Glycine max GN=IDH1
PE=2 SV=2
Length = 413
Score = 509 bits (1309), Expect = 3e-143
Identities = 249/283 (87%), Positives = 265/283 (93%), Gaps = 2/283 (0%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTF--EGKDGKTETEVFTFTGEGGVAMAMYNTDE 871
ICIGRHAFGDQYRATD VIKG G+L + F EG+ +TE EVF FTGEGGV++AMYNTDE
Sbjct: 131 ICIGRHAFGDQYRATDTVIKGAGKLKLVFVPEGQGEETEFEVFNFTGEGGVSLAMYNTDE 190
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SIR+FA+ASM TA EKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSK+EAAGIWYE
Sbjct: 191 SIRSFAEASMATALEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKFEAAGIWYE 250
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA
Sbjct: 251 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 310
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRH+RVHQKGGETSTNSIASIFAWTRGLAHRAKLDDN+KLL+FTEKLEAAC+G V
Sbjct: 311 AHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNAKLLDFTEKLEAACIGVV 370
Query: 330 ESGKMTKDLALIIHGSKLSRDTYLNTEEFIDAVAEELKTRLGA 202
E+GKMTKDLALI+HGSKLSR+ YLNTEEFIDAVA EL RL A
Sbjct: 371 EAGKMTKDLALILHGSKLSREHYLNTEEFIDAVAAELSARLSA 413
>sp|P50218|IDHC_TOBAC Isocitrate dehydrogenase [NADP] OS=Nicotiana tabacum PE=2
SV=1
Length = 415
Score = 507 bits (1305), Expect = 7e-143
Identities = 246/281 (87%), Positives = 262/281 (93%), Gaps = 2/281 (0%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTF--EGKDGKTETEVFTFTGEGGVAMAMYNTDE 871
ICIGRHAFGDQYRATD VI+G G+L + F EG D KTE EV+ FTG GGVA++MYNTDE
Sbjct: 130 ICIGRHAFGDQYRATDTVIQGAGKLKLVFVPEGTDEKTEFEVYNFTGAGGVALSMYNTDE 189
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
S+R+FA+ASMN AY+KKWPLYLSTKNTILKKYDGRFKDIFQEVYEA+WKSKYE AGIWYE
Sbjct: 190 SVRSFAEASMNMAYQKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKSKYEEAGIWYE 249
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDM AYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA
Sbjct: 250 HRLIDDMAAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 309
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRA LD+N +LL+FTEKLEAAC+G V
Sbjct: 310 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAACIGAV 369
Query: 330 ESGKMTKDLALIIHGSKLSRDTYLNTEEFIDAVAEELKTRL 208
ESGKMTKDLALIIHGSKLSRD YLNTEEFIDAVA+ELK RL
Sbjct: 370 ESGKMTKDLALIIHGSKLSRDHYLNTEEFIDAVADELKARL 410
>sp|P50217|IDHC_SOLTU Isocitrate dehydrogenase [NADP] OS=Solanum tuberosum
GN=ICDH-1 PE=2 SV=1
Length = 416
Score = 503 bits (1294), Expect = 1e-141
Identities = 246/282 (87%), Positives = 263/282 (93%), Gaps = 3/282 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTF--EGKDGKTETEVFTFTGEGGVAMAMYNTDE 871
ICIGRHAFGDQYRATD VIKG G+L + F EG D KTE EV+ FTG GGVA++MYNTDE
Sbjct: 130 ICIGRHAFGDQYRATDTVIKGAGKLKLVFVPEGSDEKTEFEVYNFTGAGGVALSMYNTDE 189
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
S+R+FA+ASMN A++KKWPLYLSTKNTILKKYDGRFKDIFQEVYEA+WKSKYE AGIWYE
Sbjct: 190 SVRSFAEASMNMAFQKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKSKYEEAGIWYE 249
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA
Sbjct: 250 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 309
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRA LD+N +LL+FTEKLEAAC+G V
Sbjct: 310 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAACIGAV 369
Query: 330 ESGKMTKDLAL-IIHGSKLSRDTYLNTEEFIDAVAEELKTRL 208
ESGKMTKDLAL IIHGSKLSR+ YLNTEEFIDAVA+ELK RL
Sbjct: 370 ESGKMTKDLALIIIHGSKLSREHYLNTEEFIDAVADELKARL 411
>sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytoplasmic OS=Microtus
mexicanus GN=IDH1 PE=2 SV=1
Length = 414
Score = 389 bits (998), Expect = 3e-107
Identities = 190/282 (67%), Positives = 225/282 (79%), Gaps = 3/282 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDG--KTETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA+GDQYRATD V+ GPG++ +TF KDG K V +F GGVAM MYN D+
Sbjct: 128 IIIGRHAYGDQYRATDFVVPGPGKVEITFTPKDGSQKVTYLVHSFEEGGGVAMGMYNQDK 187
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA +S A K WPLYLSTKNTILKKYDGRFKDIFQE+Y+ +KS++EA IWYE
Sbjct: 188 SIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYE 247
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEA
Sbjct: 248 HRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEA 307
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR+HQKG ETSTN IASIFAW+RGLAHRA+LD+N++L F + LE C+ T+
Sbjct: 308 AHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETI 367
Query: 330 ESGKMTKDLALIIHG-SKLSRDTYLNTEEFIDAVAEELKTRL 208
E+G MTKDLA I G + R YLNT EF+D + E LK +L
Sbjct: 368 EAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKL 409
>sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytoplasmic OS=Microtus
ochrogaster GN=IDH1 PE=3 SV=1
Length = 414
Score = 388 bits (995), Expect = 6e-107
Identities = 189/282 (67%), Positives = 225/282 (79%), Gaps = 3/282 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDG--KTETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA+GDQYRATD V+ GPG++ +T+ KDG K V +F GGVAM MYN D+
Sbjct: 128 IIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHSFEEGGGVAMGMYNQDK 187
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA +S A K WPLYLSTKNTILKKYDGRFKDIFQE+Y+ +KS++EA IWYE
Sbjct: 188 SIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYE 247
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEA
Sbjct: 248 HRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEA 307
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR+HQKG ETSTN IASIFAW+RGLAHRA+LD+N++L F + LE C+ T+
Sbjct: 308 AHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETI 367
Query: 330 ESGKMTKDLALIIHG-SKLSRDTYLNTEEFIDAVAEELKTRL 208
E+G MTKDLA I G + R YLNT EF+D + E LK +L
Sbjct: 368 EAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKL 409
>sp|P41562|IDHC_RAT Isocitrate dehydrogenase [NADP] cytoplasmic OS=Rattus
norvegicus GN=Idh1 PE=1 SV=1
Length = 414
Score = 387 bits (993), Expect = 1e-106
Identities = 190/282 (67%), Positives = 223/282 (79%), Gaps = 3/282 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDG--KTETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA+GDQYRATD V+ GPG++ +T+ KDG K V F GGVAM MYN D+
Sbjct: 128 IIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHDFEEGGGVAMGMYNQDK 187
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA +S A K WPLYLSTKNTILKKYDGRFKDIFQE+Y+ +KSK+EA IWYE
Sbjct: 188 SIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSKFEAQKIWYE 247
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEA
Sbjct: 248 HRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEA 307
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR++QKG ETSTN IASIFAW+RGLAHRAKLD+N++L F LE C+ T+
Sbjct: 308 AHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFANALEEVCIETI 367
Query: 330 ESGKMTKDLALIIHG-SKLSRDTYLNTEEFIDAVAEELKTRL 208
E+G MTKDLA I G + R YLNT EF+D + E LK +L
Sbjct: 368 EAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKL 409
>sp|Q9XSG3|IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytoplasmic OS=Bos taurus
GN=IDH1 PE=2 SV=1
Length = 414
Score = 386 bits (991), Expect = 2e-106
Identities = 189/282 (67%), Positives = 223/282 (79%), Gaps = 3/282 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDG--KTETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA+GDQYRATD V+ GPG++ +++ DG KT V FT GGVAM MYN D+
Sbjct: 128 IIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAMGMYNQDK 187
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA +S A K WPLYLSTKNTILKKYDGRFKDIFQE+Y+ +KS++EA IWYE
Sbjct: 188 SIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFEAQNIWYE 247
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT+EAEA
Sbjct: 248 HRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEA 307
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR++QKG ET TN IASIFAWTRGLAHRAKLD+N +L F + LE C+ T+
Sbjct: 308 AHGTVTRHYRMYQKGQETLTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALEEVCIETI 367
Query: 330 ESGKMTKDLALIIHG-SKLSRDTYLNTEEFIDAVAEELKTRL 208
E+G MTKDLA I G + R YLNT EF+D + E L+ +L
Sbjct: 368 EAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKL 409
>sp|Q6XUZ5|IDHC_SHEEP Isocitrate dehydrogenase [NADP] cytoplasmic OS=Ovis aries
GN=IDH1 PE=2 SV=1
Length = 414
Score = 386 bits (991), Expect = 2e-106
Identities = 189/282 (67%), Positives = 223/282 (79%), Gaps = 3/282 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDG--KTETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA+GDQYRATD V+ GPG++ + + DG KT V FT GGVAM M+N D+
Sbjct: 128 IIIGRHAYGDQYRATDFVVPGPGKVEICYTPSDGSPKTVYLVHNFTESGGVAMGMFNQDK 187
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA +S A K WPLYLSTKNTILKKYDGRFKDIFQE+Y+ +KS++EA IWYE
Sbjct: 188 SIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQNIWYE 247
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT+EAEA
Sbjct: 248 HRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEA 307
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR++QKG ETSTN IASIFAWTRGLAHRAKLD+N +L F + LE C+ T+
Sbjct: 308 AHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALEEVCIETI 367
Query: 330 ESGKMTKDLALIIHG-SKLSRDTYLNTEEFIDAVAEELKTRL 208
E+G MTKDLA I G + R YLNT EF+D + E L+ +L
Sbjct: 368 EAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKL 409
>sp|Q5R9C5|IDHC_PONAB Isocitrate dehydrogenase [NADP] cytoplasmic OS=Pongo
abelii GN=IDH1 PE=2 SV=2
Length = 414
Score = 382 bits (980), Expect = 4e-105
Identities = 190/282 (67%), Positives = 220/282 (78%), Gaps = 3/282 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDG--KTETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA+GDQYRATD V+ GPG++ +T+ DG K V F GGVAM MYN D+
Sbjct: 128 IIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDK 187
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA +S A K WPLYLSTKNTILKKYDGRFKDIFQE+Y+ +KS++EA IWYE
Sbjct: 188 SIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEARKIWYE 247
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT+EAEA
Sbjct: 248 HRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEA 307
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR++QKG ETSTN IASIFAWTRGLAHRAKLD+N +L F LE V T+
Sbjct: 308 AHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSVETI 367
Query: 330 ESGKMTKDLALIIHG-SKLSRDTYLNTEEFIDAVAEELKTRL 208
E+G MTKDLA I G + R YLNT EF+D + E LK +L
Sbjct: 368 EAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL 409
>sp|O75874|IDHC_HUMAN Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo
sapiens GN=IDH1 PE=1 SV=2
Length = 414
Score = 382 bits (979), Expect = 5e-105
Identities = 189/282 (67%), Positives = 220/282 (78%), Gaps = 3/282 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDG--KTETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA+GDQYRATD V+ GPG++ +T+ DG K V F GGVAM MYN D+
Sbjct: 128 IIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDK 187
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA +S A K WPLYLSTKNTILKKYDGRFKDIFQE+Y+ +KS++EA IWYE
Sbjct: 188 SIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYE 247
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT+EAEA
Sbjct: 248 HRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEA 307
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR++QKG ETSTN IASIFAWTRGLAHRAKLD+N +L F LE + T+
Sbjct: 308 AHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETI 367
Query: 330 ESGKMTKDLALIIHG-SKLSRDTYLNTEEFIDAVAEELKTRL 208
E+G MTKDLA I G + R YLNT EF+D + E LK +L
Sbjct: 368 EAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL 409
>sp|O88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytoplasmic OS=Mus
musculus GN=Idh1 PE=1 SV=1
Length = 414
Score = 382 bits (979), Expect = 5e-105
Identities = 188/282 (66%), Positives = 223/282 (79%), Gaps = 3/282 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDG--KTETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA+GDQYRATD V+ GPG++ +T+ KDG K V F GGVAM MYN D+
Sbjct: 128 IIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAMGMYNQDK 187
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA +S A K WPLYLSTKNTILKKYDGRFKDIFQE+Y+ +KS++EA I YE
Sbjct: 188 SIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQNICYE 247
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEA
Sbjct: 248 HRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEA 307
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR++QKG ETSTN IASIFAW+RGLAHRAKLD+N++L F + LE C+ T+
Sbjct: 308 AHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETI 367
Query: 330 ESGKMTKDLALIIHG-SKLSRDTYLNTEEFIDAVAEELKTRL 208
E+G MTKDLA I G + R YLNT EF+D + E LK +L
Sbjct: 368 EAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKL 409
>sp|P33198|IDHP_PIG Isocitrate dehydrogenase [NADP], mitochondrial (Fragment)
OS=Sus scrofa GN=IDH2 PE=1 SV=1
Length = 421
Score = 369 bits (945), Expect = 4e-101
Identities = 186/284 (65%), Positives = 210/284 (73%), Gaps = 5/284 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDGKT--ETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA GDQY+ATD V+ G + F KDG + + EV+ F GGV M MYNTDE
Sbjct: 137 ITIGRHAHGDQYKATDFVVDRAGTFKIVFTPKDGSSAKQWEVYNFPA-GGVGMGMYNTDE 195
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA + A +KKWPLY+STKNTILK YDGRFKDIFQE++E +K+ ++ IWYE
Sbjct: 196 SISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKYKIWYE 255
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA LKS GG+VWACKNYDGDVQSD LAQGFGSLGLMTSVLVCPDGKTIEAEA
Sbjct: 256 HRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEA 315
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR HQKG TSTN IASIFAWTRGL HR KLD N L+ F + LE CV TV
Sbjct: 316 AHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETV 375
Query: 330 ESGKMTKDLALIIHG--SKLSRDTYLNTEEFIDAVAEELKTRLG 205
ESG MTKDLA IHG + + +LNT +F+D + L LG
Sbjct: 376 ESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALG 419
>sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitochondrial OS=Mus
musculus GN=Idh2 PE=1 SV=3
Length = 452
Score = 368 bits (944), Expect = 5e-101
Identities = 186/284 (65%), Positives = 210/284 (73%), Gaps = 5/284 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDGKT--ETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA GDQY+ATD V+ G + F KDG + E EV+ F GGV M MYNTDE
Sbjct: 168 ITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFPA-GGVGMGMYNTDE 226
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA + + +KKWPLYLSTKNTILK YDGRFKDIFQE+++ +K+ ++ IWYE
Sbjct: 227 SISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYE 286
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA LKS GG+VWACKNYDGDVQSD LAQGFGSLGLMTSVLVCPDGKTIEAEA
Sbjct: 287 HRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEA 346
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR HQKG TSTN IASIFAWTRGL HR KLD N L+ F + LE CV TV
Sbjct: 347 AHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTV 406
Query: 330 ESGKMTKDLALIIHG--SKLSRDTYLNTEEFIDAVAEELKTRLG 205
ESG MTKDLA IHG + + +LNT +F+D + L LG
Sbjct: 407 ESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 450
>sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitochondrial OS=Bos
taurus GN=IDH2 PE=1 SV=2
Length = 452
Score = 367 bits (942), Expect = 9e-101
Identities = 186/284 (65%), Positives = 209/284 (73%), Gaps = 5/284 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDGK--TETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA GDQY+ATD V+ G + F KDG E EV+ F GGV M MYNTDE
Sbjct: 168 ITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFPA-GGVGMGMYNTDE 226
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA + A +KKWPLY+STKNTILK YDGRFKDIFQ ++E +K++++ IWYE
Sbjct: 227 SISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDKHKIWYE 286
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA LKS GG+VWACKNYDGDVQSD LAQGFGSLGLMTSVLVCPDGKTIEAEA
Sbjct: 287 HRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEA 346
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR HQKG TSTN IASIFAWTRGL HR KLD N L+ F + LE CV TV
Sbjct: 347 AHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETV 406
Query: 330 ESGKMTKDLALIIHG--SKLSRDTYLNTEEFIDAVAEELKTRLG 205
ESG MTKDLA IHG + + +LNT +F+D + L LG
Sbjct: 407 ESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALG 450
>sp|P48735|IDHP_HUMAN Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo
sapiens GN=IDH2 PE=1 SV=2
Length = 452
Score = 367 bits (942), Expect = 9e-101
Identities = 187/284 (65%), Positives = 208/284 (73%), Gaps = 5/284 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDGK--TETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA GDQY+ATD V G M F KDG E EV+ F GGV M MYNTDE
Sbjct: 168 ITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPA-GGVGMGMYNTDE 226
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA + A +KKWPLY+STKNTILK YDGRFKDIFQE+++ +K+ ++ IWYE
Sbjct: 227 SISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYE 286
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA LKS GG+VWACKNYDGDVQSD LAQGFGSLGLMTSVLVCPDGKTIEAEA
Sbjct: 287 HRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEA 346
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR HQKG TSTN IASIFAWTRGL HR KLD N L+ F + LE CV TV
Sbjct: 347 AHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETV 406
Query: 330 ESGKMTKDLALIIHG--SKLSRDTYLNTEEFIDAVAEELKTRLG 205
ESG MTKDLA IHG + + +LNT +F+D + L LG
Sbjct: 407 ESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 450
>sp|Q4R502|IDHP_MACFA Isocitrate dehydrogenase [NADP], mitochondrial OS=Macaca
fascicularis GN=IDH2 PE=2 SV=1
Length = 452
Score = 367 bits (942), Expect = 9e-101
Identities = 187/284 (65%), Positives = 208/284 (73%), Gaps = 5/284 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDGK--TETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA GDQY+ATD V G M F KDG E EV+ F GGV M MYNTDE
Sbjct: 168 ITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPA-GGVGMGMYNTDE 226
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA + A +KKWPLY+STKNTILK YDGRFKDIFQE+++ +K+ ++ IWYE
Sbjct: 227 SISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYE 286
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA LKS GG+VWACKNYDGDVQSD LAQGFGSLGLMTSVLVCPDGKTIEAEA
Sbjct: 287 HRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEA 346
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR HQKG TSTN IASIFAWTRGL HR KLD N L+ F + LE CV TV
Sbjct: 347 AHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETV 406
Query: 330 ESGKMTKDLALIIHG--SKLSRDTYLNTEEFIDAVAEELKTRLG 205
ESG MTKDLA IHG + + +LNT +F+D + L LG
Sbjct: 407 ESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 450
>sp|P56574|IDHP_RAT Isocitrate dehydrogenase [NADP], mitochondrial OS=Rattus
norvegicus GN=Idh2 PE=1 SV=2
Length = 452
Score = 367 bits (940), Expect = 2e-100
Identities = 185/284 (65%), Positives = 209/284 (73%), Gaps = 5/284 (1%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDGK--TETEVFTFTGEGGVAMAMYNTDE 871
I IGRHA GDQY+ATD V+ G + F KDG E EV+ F GGV M MYNTDE
Sbjct: 168 ITIGRHAHGDQYKATDFVVDRAGMFKLVFTPKDGSGAKEWEVYNFPA-GGVGMGMYNTDE 226
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA + + +KKWPLYLSTKNTI+K YDGRFKDIFQE+++ +K+ ++ IWYE
Sbjct: 227 SISGFAHSCFQYSIQKKWPLYLSTKNTIMKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYE 286
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA LKS GG+VWACKNYDGDVQSD LAQGFGSLGLMTSVLVCPDGKTIEAEA
Sbjct: 287 HRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEA 346
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR HQKG TSTN IASIFAWTRGL HR KLD N L+ F + LE CV TV
Sbjct: 347 AHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTV 406
Query: 330 ESGKMTKDLALIIHG--SKLSRDTYLNTEEFIDAVAEELKTRLG 205
ESG MTKDLA IHG + + +LNT +F+D + L LG
Sbjct: 407 ESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 450
>sp|O14254|IDHP_SCHPO Probable isocitrate dehydrogenase [NADP], mitochondrial
OS=Schizosaccharomyces pombe GN=idp1 PE=2 SV=1
Length = 418
Score = 357 bits (914), Expect = 2e-097
Identities = 179/282 (63%), Positives = 215/282 (76%), Gaps = 8/282 (2%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTFEGKDGKTETE---VFTFTGEGGVAMAMYNTD 874
ICIGRHAFGDQY++TD V GPG+L ++F K + E V+ F G GVAM+MYNTD
Sbjct: 138 ICIGRHAFGDQYKSTDLVASGPGKLELSFTPKGNPSAKETYNVYEFNG-SGVAMSMYNTD 196
Query: 873 ESIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWY 694
+SIR FA +S A +KK PLYLSTKNTILKKYDGRFKD FQEVYE+ +K K+E G+WY
Sbjct: 197 DSIRGFAHSSFQMALQKKMPLYLSTKNTILKKYDGRFKDTFQEVYESDYKQKFEELGLWY 256
Query: 693 EHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAE 514
+HRLIDDMVA A+KS GG+VWACKNYDGDV SD +AQ +GSLGLMTSVL+ P+G+T E+E
Sbjct: 257 QHRLIDDMVAQAIKSNGGFVWACKNYDGDVMSDVVAQAYGSLGLMTSVLIHPNGRTFESE 316
Query: 513 AAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGT 334
AAHGTV RHY + KG +TSTNSIASIFAWTRGLAHR +LD N +L++F LE ACV
Sbjct: 317 AAHGTVQRHYMQYLKGKKTSTNSIASIFAWTRGLAHRGRLDGNERLVKFANALEHACVRC 376
Query: 333 VESGKMTKDLALIIHGSKLSRDTYLNTEEFIDAVAEELKTRL 208
VE G MTKDL L+ S + Y++T EF+DAV EL + L
Sbjct: 377 VEKGIMTKDLYLL----SKSPNGYVDTFEFLDAVKSELDSEL 414
>sp|O13285|IDH1_CANTR Isocitrate dehydrogenase [NADP], mitochondrial OS=Candida
tropicalis GN=IDP1 PE=3 SV=1
Length = 430
Score = 347 bits (890), Expect = 1e-094
Identities = 180/279 (64%), Positives = 212/279 (75%), Gaps = 6/279 (2%)
Frame = -1
Query: 1044 ICIGRHAFGDQYRATDAVIKGPGRLTMTF-EGKDGKTETE-VFTFTGEGGVAMAMYNTDE 871
I IGRHAFGDQY+ATD VI PGRL + F G+ +T+ V+ +TG GV +AMYNTDE
Sbjct: 154 IVIGRHAFGDQYKATDLVINEPGRLELRFTPASGGEAQTQKVYDYTGP-GVGLAMYNTDE 212
Query: 870 SIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAAGIWYE 691
SI FA AS A K PLY+STKNTILKKYDGRFKDIFQ++YE + +++E G+WYE
Sbjct: 213 SITGFAHASFKMALAKGLPLYMSTKNTILKKYDGRFKDIFQQIYEQDYAAEFEKQGLWYE 272
Query: 690 HRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEA 511
HRLIDDMVA +KS+GG+V A KNYDGDVQSD +AQGFGSLGLMTS L+ PDGK EAEA
Sbjct: 273 HRLIDDMVAQMIKSKGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSALMTPDGKAYEAEA 332
Query: 510 AHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNSKLLEFTEKLEAACVGTV 331
AHGTVTRHYR HQ+G ETSTNSIASIFAWTRGLA R KLD+ +++F KLE A + TV
Sbjct: 333 AHGTVTRHYRQHQQGKETSTNSIASIFAWTRGLAQRGKLDETPDVVDFASKLEQATIDTV 392
Query: 330 ESGK-MTKDLALIIHGSKLSRDTYLNTEEFIDAVAEELK 217
E + MTKDLAL + K R Y+ T EF+DAVA+ LK
Sbjct: 393 EVDRIMTKDLALAM--GKTDRSAYVTTTEFLDAVADRLK 429
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,889,068,748
Number of Sequences: 518415
Number of Extensions: 64889068748
Number of Successful Extensions: 459589147
Number of sequences better than 0.0: 0
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