BLASTX 7.6.2
Query= UN16162 /QuerySize=1697
(1696 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9SEE5|GALK1_ARATH Galactokinase OS=Arabidopsis thaliana GN=G... 898 2e-260
sp|Q54DN6|GALK_DICDI Galactokinase OS=Dictyostelium discoideum G... 342 6e-093
sp|Q5XIG6|GALK2_RAT N-acetylgalactosamine kinase OS=Rattus norve... 334 2e-090
sp|Q5R6J8|GALK2_PONAB N-acetylgalactosamine kinase OS=Pongo abel... 332 6e-090
sp|Q01415|GALK2_HUMAN N-acetylgalactosamine kinase OS=Homo sapie... 331 1e-089
sp|Q68FH4|GALK2_MOUSE N-acetylgalactosamine kinase OS=Mus muscul... 326 3e-088
sp|Q9HDU2|GAL1_SCHPO Galactokinase OS=Schizosaccharomyces pombe ... 184 2e-045
sp|P13045|GAL3_YEAST Protein GAL3 OS=Saccharomyces cerevisiae GN... 161 2e-038
sp|P04385|GAL1_YEAST Galactokinase OS=Saccharomyces cerevisiae G... 143 5e-033
sp|P09608|GAL1_KLULA Galactokinase OS=Kluyveromyces lactis GN=GA... 109 8e-023
sp|O42821|GAL1_CANPA Galactokinase OS=Candida parapsilosis GN=GA... 87 3e-016
sp|P56091|GAL1_CANAL Galactokinase OS=Candida albicans GN=GAL1 P... 77 3e-013
sp|C4LB24|GAL1_TOLAT Galactokinase OS=Tolumonas auensis (strain ... 65 1e-009
>sp|Q9SEE5|GALK1_ARATH Galactokinase OS=Arabidopsis thaliana GN=GAL1 PE=2 SV=2
Length = 496
Score = 898 bits (2320), Expect = 2e-260
Identities = 448/496 (90%), Positives = 471/496 (94%)
Frame = +1
Query: 37 MAKQEEVTVPIFSSLDHVYGEGSQLQEAKSRFDALKSKFNQAFDASPQLFARSPGRVNLI 216
MAK EEV+VPIF+SL+ VYGEGS LQEA RFD LK+ FN F ASPQLFARSPGRVNLI
Sbjct: 1 MAKPEEVSVPIFTSLEPVYGEGSLLQEATQRFDVLKANFNDVFGASPQLFARSPGRVNLI 60
Query: 217 GEHIDYEGYSVLPMAIRQDTIIAIRKREGSNELRIANVNEKYSMCTYPADPHQEIDLQNH 396
GEHIDYEGYSVLPMAIRQDTIIAIRK E +LRIANVN+KY+MCTYPADP QEIDL+NH
Sbjct: 61 GEHIDYEGYSVLPMAIRQDTIIAIRKCEDQKQLRIANVNDKYTMCTYPADPDQEIDLKNH 120
Query: 397 KWGHYFICAYKGFHEYAKSKGVNVDSPVGLDVVVDGIVPTGSGLSSSAAFVCSSTIAIMA 576
KWGHYFICAYKGFHEYAKSKGVN+ SPVGLDV+VDGIVPTGSGLSSSAAFVCS+TIAIMA
Sbjct: 121 KWGHYFICAYKGFHEYAKSKGVNLGSPVGLDVLVDGIVPTGSGLSSSAAFVCSATIAIMA 180
Query: 577 VFGENFEKKELAQLTCECEHHIGTQSGGMDQAISIMAKTGFAELIDFNPVRATDVKLPHG 756
VFG NFEKKELAQLTCECE HIGTQSGGMDQAISIMAKTGFAELIDFNPVRATDVKLP G
Sbjct: 181 VFGHNFEKKELAQLTCECERHIGTQSGGMDQAISIMAKTGFAELIDFNPVRATDVKLPDG 240
Query: 757 GSFVIAHSLAESQKAVTAATNYNNRVVECRLASIILGIKLGMEPKEAISKVKTLSDVEGL 936
GSFVIAHSLAESQKAVTAA NYNNRVVECRLASIILG+KLGMEPKEAISKVKTLSDVEGL
Sbjct: 241 GSFVIAHSLAESQKAVTAAKNYNNRVVECRLASIILGVKLGMEPKEAISKVKTLSDVEGL 300
Query: 937 CVSFAGDRGSSDPVLAVKEYLKEEPYTAEEIEKIVQEKLPSILNNDPTSLAVLNAATHFK 1116
CVSFAGDRGSSDP+LAVKEYLKEEPYTAEEIEKI++EKLPSI+NNDPTSLAVLNAATHFK
Sbjct: 301 CVSFAGDRGSSDPLLAVKEYLKEEPYTAEEIEKILEEKLPSIVNNDPTSLAVLNAATHFK 360
Query: 1117 LHQRAAHVYSEARRVHGFKDTVDSNLSDEEKLKKLGDLMNESHYSCSVLYECSCPELEEL 1296
LHQRAAHVYSEARRVHGFKDTV+SNLSDEEKLKKLGDLMNESHYSCSVLYECSCPELEEL
Sbjct: 361 LHQRAAHVYSEARRVHGFKDTVNSNLSDEEKLKKLGDLMNESHYSCSVLYECSCPELEEL 420
Query: 1297 VKVSRENGALGARLTGAGWGGCTVALVKESGVSQFIAAVKDKYYKKRIEKGVVKEEDMEL 1476
V+V +ENGALGARLTGAGWGGC VALVKE V+QFI AVK+KYYKKR+EKGVVK+EDMEL
Sbjct: 421 VQVCKENGALGARLTGAGWGGCAVALVKEFDVTQFIPAVKEKYYKKRVEKGVVKKEDMEL 480
Query: 1477 YLFASKPSSGAAIFNL 1524
YLFASKPSSGAAIFNL
Sbjct: 481 YLFASKPSSGAAIFNL 496
>sp|Q54DN6|GALK_DICDI Galactokinase OS=Dictyostelium discoideum GN=galK PE=3
SV=1
Length = 501
Score = 342 bits (876), Expect = 6e-093
Identities = 202/504 (40%), Positives = 300/504 (59%), Gaps = 39/504 (7%)
Frame = +1
Query: 67 IFSSLDHVYGEGSQLQEAKSRFDALKSKFNQAFDA-SPQLFARSPGRVNLIGEHIDYEGY 243
I SLD +Y + K R++ L F++ ++ P + R+PGRVNLIGEH+DY GY
Sbjct: 11 IVESLDDIY---KNFENNKKRYEELNETFSKIYNGDKPIFYFRAPGRVNLIGEHVDYSGY 67
Query: 244 SVLPMAIRQDTIIAIRKREGSNE-LRIANVNEKYS--MCTYPADPHQEIDLQNHKWGHYF 414
VLP A+ QDTI+A+ + +N+ + I N NEKY+ EID++ H W +Y
Sbjct: 68 CVLPFALEQDTIVAVSFNKLNNDIINIHNCNEKYTPKSIDVSGGGDIEIDMKRHHWTNYV 127
Query: 415 ICAYKGFHEYAKSKGVNVDSPVGLDVVVDGIVPTGSGLSSSAAFVCSSTIAIMAVFGENF 594
+ A+KG + A KG + S ++++ G VP G+G+SSS+A VC ST+AI
Sbjct: 128 LAAWKGVSQ-AMEKGGKLKS---VNLLYSGNVPMGAGVSSSSALVCVSTLAISYCNNLIL 183
Query: 595 EKKELAQLTCECEHHIGTQSGGMDQAISIMAKTGFAELIDFNP-VRATDVKLPHGGSFVI 771
K+ELAQL+ + E ++G +SGGMDQ+IS +A+ A+LI+F+P ++ DV+LP G SFVI
Sbjct: 184 NKEELAQLSIKSERYVGVESGGMDQSISFLAEQNTAKLIEFHPSLKTFDVQLPKGVSFVI 243
Query: 772 AHSLAESQKAVTAATNYNNRVVECRLASIILGIKLGMEPKEAISKVKTLSDVEGLCVSFA 951
+SL +S K VT ATNYN RVVECRLA+++L G+ + KV+ L DV+ +
Sbjct: 244 CNSLVDSLKVVTGATNYNLRVVECRLAAVLLAFHCGL----SWEKVRRLRDVQ-----YQ 294
Query: 952 GDRGSSDPVLAVKEYLKE-EPYTAEEIEKIVQEKLPSILNN-DPTSLAVLNAATHFKLHQ 1125
G+ + +++L E + YT EE+ I+ + ++ P+ + V + HF+L++
Sbjct: 295 GNFDLPQLIQLTEQHLSEKQTYTREEVATILDISVEQLVKTYFPSGITV--QSEHFELYK 352
Query: 1126 RAAHVYSEARRVHGFKDTV--DSNLSDEEK------------LKKLGDLMNESHYSCSVL 1263
RA HV++E +RV+ F + SN ++ +++LG LMNESH SCS L
Sbjct: 353 RARHVFTETQRVYKFSEICKQQSNFNNNNNNNNNNSSNNTNIIQELGKLMNESHESCSKL 412
Query: 1264 YECSCPELEELVKVSRENGALGARLTGAGWGGCTVALVKESGVSQFIAAVKDKYYKKRIE 1443
+ECSC EL+ L K+ RENGALG+RLTGAGWGGC ++LV S V F+ A+ YY K +
Sbjct: 413 FECSCSELDSLTKICRENGALGSRLTGAGWGGCVISLVPNSKVDSFLDAIDTHYYSKFVN 472
Query: 1444 KGVVKEEDMELYLFASKPSSGAAI 1515
+K + Y F + P GA I
Sbjct: 473 PEKLKNIEKSSYSFFTTPCKGACI 496
>sp|Q5XIG6|GALK2_RAT N-acetylgalactosamine kinase OS=Rattus norvegicus GN=Galk2
PE=2 SV=1
Length = 458
Score = 334 bits (854), Expect = 2e-090
Identities = 196/462 (42%), Positives = 286/462 (61%), Gaps = 32/462 (6%)
Frame = +1
Query: 139 LKSKFNQAFDASPQLFARSPGRVNLIGEHIDYEGYSVLPMAIRQDTIIAIRKREGSNELR 318
LK FN F ++P+ + R+PGRVN+IGEHIDY GYSVLPMA+ QD +IA+ + + L+
Sbjct: 22 LKEMFNSKFGSTPKFYVRAPGRVNIIGEHIDYCGYSVLPMAVEQDMLIAVGPVK-TQTLQ 80
Query: 319 IANVNEKYSMCTYPADPHQEIDLQNHKWGHYFICAYKGFHEYAKSKGVNVDSPVGLDVVV 498
+AN + Y + A+ + ID W +YF+C +KG E+ + G++ +V
Sbjct: 81 LANTDPLYPDFSTTAN-NICIDKTQPLWHNYFLCGFKGIQEH-----FGLTQLPGMNCLV 134
Query: 499 DGIVPTGSGLSSSAAFVCSSTIAIMAVFGENFEKKELAQLTCECEHHIGTQSGGMDQAIS 678
DG +P SGLSSS+A VC + + + V G K ELA++ + E +IGT+ GGMDQ+IS
Sbjct: 135 DGNIPPSSGLSSSSALVCCAGLVTLTVLGMRLSKVELAEICAKSERYIGTEGGGMDQSIS 194
Query: 679 IMAKTGFAELIDFNPVRATDVKLPHGGSFVIAHSLAESQKAVTAATNYNNRVVECRLASI 858
+A+ G A+LI+F+P+RATDVKLP G FVIA+S E KA T +++N RV+ECRLA+
Sbjct: 195 FLAEEGTAKLIEFSPLRATDVKLPSGAVFVIANSCVEMNKAAT--SHFNVRVMECRLAAK 252
Query: 859 ILGIKLGMEPKEAISKVKTLSDVEG-LCVSFAGDRGSSDPVLAVKEYLKEEPYTAEEIEK 1035
+L G++ KV L +V+ L +S + +L ++ L EPY+ EEI K
Sbjct: 253 VLAKHKGLQ----WDKVLRLEEVQSELGISL------EEMLLVTEDALHAEPYSREEICK 302
Query: 1036 IVQEKLPSILNN--DPTSLAVLNAATHFKLHQRAAHVYSEARRVHGFKDTVDSNLSDEEK 1209
+ L + P + L FKL+QRA HVYSEA RV FK ++ + +
Sbjct: 303 CLGISLEELRTQILSPNTQGELT----FKLYQRAKHVYSEAARVLQFKQVCEA--APDNA 356
Query: 1210 LKKLGDLMNESHYSCSVLYECSCPELEELVKVSRENGALGARLTGAGWGGCTVALVKESG 1389
++ LG+LMN+SH SC +YECSCPEL++LV + R+ GA G+RLTGAGWGGCTV+LV
Sbjct: 357 VQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLVPADT 416
Query: 1390 VSQFIAAVKDKYYKKRIEKGVVKEEDMELYLFASKPSSGAAI 1515
+S F+A+V + YY+ + + + +E+ LFA+KP GA +
Sbjct: 417 LSSFLASVHEAYYQGNMSR-LAREKHS---LFATKPGGGALV 454
>sp|Q5R6J8|GALK2_PONAB N-acetylgalactosamine kinase OS=Pongo abelii GN=GALK2
PE=2 SV=1
Length = 458
Score = 332 bits (850), Expect = 6e-090
Identities = 198/462 (42%), Positives = 280/462 (60%), Gaps = 32/462 (6%)
Frame = +1
Query: 139 LKSKFNQAFDASPQLFARSPGRVNLIGEHIDYEGYSVLPMAIRQDTIIAIRKREGSNELR 318
LK FN F + P+ + R+PGRVN+IGEHIDY GYSVLPMA+ QD +IA+ + + L+
Sbjct: 22 LKEMFNSKFGSIPKFYVRAPGRVNIIGEHIDYCGYSVLPMAVEQDVLIAVEPVK-TYTLQ 80
Query: 319 IANVNEKYSMCTYPADPHQEIDLQNHKWGHYFICAYKGFHEYAKSKGVNVDSPVGLDVVV 498
+AN N Y + A+ + +ID W +YF+C KG E+ V + G++ +V
Sbjct: 81 LANTNPLYPDLSTSAN-NIQIDKTKPLWHNYFLCGLKGIQEH-----FGVSNLTGMNCLV 134
Query: 499 DGIVPTGSGLSSSAAFVCSSTIAIMAVFGENFEKKELAQLTCECEHHIGTQSGGMDQAIS 678
DG +P SGLSSS+A VC + + + V G N K ELA++ + E +IGT+ GGMDQ+IS
Sbjct: 135 DGNIPPSSGLSSSSALVCCAGLVTLTVLGRNLSKVELAEICAKSERYIGTEGGGMDQSIS 194
Query: 679 IMAKTGFAELIDFNPVRATDVKLPHGGSFVIAHSLAESQKAVTAATNYNNRVVECRLASI 858
+A+ G A+LI+F+P+RATDVKLP G FVIA+S E KA T +++N RV+ECRLA+
Sbjct: 195 FLAEEGTAKLIEFSPLRATDVKLPSGAVFVIANSCVEMNKAAT--SHFNIRVMECRLAAK 252
Query: 859 ILGIKLGMEPKEAISKVKTLSDVEG-LCVSFAGDRGSSDPVLAVKEYLKEEPYTAEEIEK 1035
+L ++ KV L +V+ L +S + +L ++ L EPY EEI +
Sbjct: 253 LLAKYKSLQ----WDKVLRLEEVQAKLGISL------EEMLLVTEDALHPEPYNPEEICR 302
Query: 1036 IVQEKLPSILNN--DPTSLAVLNAATHFKLHQRAAHVYSEARRVHGFKDTVDSNLSDEEK 1209
+ L + P + VL FKL+QRA HVYSEA RV FK + + E
Sbjct: 303 CLGISLEELRTQILSPNTQDVL----IFKLYQRAKHVYSEAARVLQFKKICEE--APENM 356
Query: 1210 LKKLGDLMNESHYSCSVLYECSCPELEELVKVSRENGALGARLTGAGWGGCTVALVKESG 1389
++ LG+LMN+SH SC +YECSCPEL++LV + R+ GA G+RLTGAGWGGCTV++V
Sbjct: 357 VQLLGELMNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTVSIVPADK 416
Query: 1390 VSQFIAAVKDKYYKKRIEKGVVKEEDMELYLFASKPSSGAAI 1515
+ F+A V YY R + + E+ LFA+KP GA +
Sbjct: 417 LPSFLANVHKAYY-HRSDGSLAPEKQS---LFATKPGGGALV 454
>sp|Q01415|GALK2_HUMAN N-acetylgalactosamine kinase OS=Homo sapiens GN=GALK2
PE=1 SV=1
Length = 458
Score = 331 bits (848), Expect = 1e-089
Identities = 197/462 (42%), Positives = 281/462 (60%), Gaps = 32/462 (6%)
Frame = +1
Query: 139 LKSKFNQAFDASPQLFARSPGRVNLIGEHIDYEGYSVLPMAIRQDTIIAIRKREGSNELR 318
LK FN F + P+ + R+PGRVN+IGEHIDY GYSVLPMA+ QD +IA+ + + L+
Sbjct: 22 LKEMFNSKFGSIPKFYVRAPGRVNIIGEHIDYCGYSVLPMAVEQDVLIAVEPVK-TYALQ 80
Query: 319 IANVNEKYSMCTYPADPHQEIDLQNHKWGHYFICAYKGFHEYAKSKGVNVDSPVGLDVVV 498
+AN N Y + A+ + +ID W +YF+C KG E+ + + G++ +V
Sbjct: 81 LANTNPLYPDFSTSAN-NIQIDKTKPLWHNYFLCGLKGIQEH-----FGLSNLTGMNCLV 134
Query: 499 DGIVPTGSGLSSSAAFVCSSTIAIMAVFGENFEKKELAQLTCECEHHIGTQSGGMDQAIS 678
DG +P SGLSSS+A VC + + + V G N K ELA++ + E +IGT+ GGMDQ+IS
Sbjct: 135 DGNIPPSSGLSSSSALVCCAGLVTLTVLGRNLSKVELAEICAKSERYIGTEGGGMDQSIS 194
Query: 679 IMAKTGFAELIDFNPVRATDVKLPHGGSFVIAHSLAESQKAVTAATNYNNRVVECRLASI 858
+A+ G A+LI+F+P+RATDVKLP G FVIA+S E KA T +++N RV+ECRLA+
Sbjct: 195 FLAEEGTAKLIEFSPLRATDVKLPSGAVFVIANSCVEMNKAAT--SHFNIRVMECRLAAK 252
Query: 859 ILGIKLGMEPKEAISKVKTLSDVEG-LCVSFAGDRGSSDPVLAVKEYLKEEPYTAEEIEK 1035
+L ++ KV L +V+ L +S + +L ++ L EPY EEI +
Sbjct: 253 LLAKYKSLQ----WDKVLRLEEVQAKLGISL------EEMLLVTEDALHPEPYNPEEICR 302
Query: 1036 IVQEKLPSILNN--DPTSLAVLNAATHFKLHQRAAHVYSEARRVHGFKDTVDSNLSDEEK 1209
+ L + P + VL FKL+QRA HVYSEA RV FK + + E
Sbjct: 303 CLGISLEELRTQILSPNTQDVL----IFKLYQRAKHVYSEAARVLQFKKICEE--APENM 356
Query: 1210 LKKLGDLMNESHYSCSVLYECSCPELEELVKVSRENGALGARLTGAGWGGCTVALVKESG 1389
++ LG+LMN+SH SC +YECSCPEL++LV + R+ GA G+RLTGAGWGGCTV++V
Sbjct: 357 VQLLGELMNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTVSMVPADK 416
Query: 1390 VSQFIAAVKDKYYKKRIEKGVVKEEDMELYLFASKPSSGAAI 1515
+ F+A V YY +R + + E+ LFA+KP GA +
Sbjct: 417 LPSFLANVHKAYY-QRSDGSLAPEKQS---LFATKPGGGALV 454
>sp|Q68FH4|GALK2_MOUSE N-acetylgalactosamine kinase OS=Mus musculus GN=Galk2
PE=1 SV=1
Length = 458
Score = 326 bits (835), Expect = 3e-088
Identities = 187/461 (40%), Positives = 283/461 (61%), Gaps = 30/461 (6%)
Frame = +1
Query: 139 LKSKFNQAFDASPQLFARSPGRVNLIGEHIDYEGYSVLPMAIRQDTIIAIRKREGSNELR 318
LK FN F ++P+ + R+PGRVN+IGEHIDY GYSV+PMA+ QD +IA+ + ++ L+
Sbjct: 22 LKEMFNSKFGSTPKFYVRAPGRVNIIGEHIDYCGYSVIPMAVEQDMLIAVEPVK-THTLQ 80
Query: 319 IANVNEKYSMCTYPADPHQEIDLQNHKWGHYFICAYKGFHEYAKSKGVNVDSPVGLDVVV 498
+AN + Y + A+ + ID W +YF+C +KG E+ + G++ +V
Sbjct: 81 LANTDPLYPDFSTTAN-NICIDKTKPLWHNYFLCGFKGIQEH-----FGLSKLPGMNCLV 134
Query: 499 DGIVPTGSGLSSSAAFVCSSTIAIMAVFGENFEKKELAQLTCECEHHIGTQSGGMDQAIS 678
DG +P SGLSSS+A VC + + + V G K ELA++ + E +IGT+ GGMDQ+IS
Sbjct: 135 DGNIPPSSGLSSSSALVCCAGLVTLTVLGLRLSKVELAEICAKSERYIGTEGGGMDQSIS 194
Query: 679 IMAKTGFAELIDFNPVRATDVKLPHGGSFVIAHSLAESQKAVTAATNYNNRVVECRLASI 858
+A+ G A+LI+F+P+RAT+VKLP G FVIA+S E KA T +++N RV+ECRLA+
Sbjct: 195 FLAEEGTAKLIEFSPLRATNVKLPSGAVFVIANSCMEMNKAAT--SHFNVRVMECRLAAK 252
Query: 859 ILGIKLGMEPKEAISKVKTLSDVEGLCVSFAGDRGSSDPVLAVKEYLKEEPYTAEEIEKI 1038
+L G++ + + +++ + G+ + + +L ++ L EPY+ EEI +
Sbjct: 253 VLAKHKGLQ-WDNVLRLEEVQSKLGISL--------EEMLLVTEDALHPEPYSREEICRC 303
Query: 1039 VQEKLPSILNNDPTSLAVLNAATH--FKLHQRAAHVYSEARRVHGFKDTVDSNLSDEEKL 1212
+ L + T + N FKL+QRA HVYSEA RV FK + + + +
Sbjct: 304 LGISLERL----RTQILTPNTQDELTFKLYQRAKHVYSEAARVLQFKQVCED--APDNAV 357
Query: 1213 KKLGDLMNESHYSCSVLYECSCPELEELVKVSRENGALGARLTGAGWGGCTVALVKESGV 1392
+ LG+LMN+SH SC +YECSCPEL++LV + R+ GA G+RLTGAGWGGCTV+LV +
Sbjct: 358 QLLGELMNQSHRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLVPADML 417
Query: 1393 SQFIAAVKDKYYKKRIEKGVVKEEDMELYLFASKPSSGAAI 1515
S F+A+V + YY+ + ++ LFA+KP GA +
Sbjct: 418 SSFLASVHEAYYQGNTSRLAQEKHS----LFATKPGGGALV 454
>sp|Q9HDU2|GAL1_SCHPO Galactokinase OS=Schizosaccharomyces pombe GN=gal1 PE=2
SV=1
Length = 519
Score = 184 bits (467), Expect = 2e-045
Identities = 118/286 (41%), Positives = 165/286 (57%), Gaps = 14/286 (4%)
Frame = +1
Query: 103 SQLQEAKSRFDALKSKFNQAFDASPQLFARSPGRVNLIGEHIDYEGYSVLPMAIRQDTII 282
S +E K+R+ L + F Q + P F+RSPGRVN+IGEHIDY +SVLPMAI D I+
Sbjct: 14 SNPKENKARYAKLLNSFEQKYHCKPDFFSRSPGRVNIIGEHIDYNYFSVLPMAIDVDVIV 73
Query: 283 AIRKREGSN-ELRIANVNEKYSMCTYPADPHQ-EIDLQNHKWGHYFICAYKGFHEYAKSK 456
++ + + EL N K + P+D EI+ +H WG+YF C+ H+Y K
Sbjct: 74 SVTTSDDAKVELNNTNPEFKEEILELPSDGAVIEINKTHHTWGNYFRCSMIVAHKYILEK 133
Query: 457 GVNVDS----PV-GLDVVVDGIVPTGSGLSSSAAFVCSSTIAIMAVFGEN-FEKKELAQL 618
+ S P+ GL ++ DG VPTG GLSSSAAF +S +AI+ G N K++L ++
Sbjct: 134 YPELVSGGKKPLKGLKLIFDGNVPTGGGLSSSAAFCVASILAILKANGINTITKEDLVKI 193
Query: 619 TCECEHHIGTQSGGMDQAISIMAKTGFAELIDFNP-VRATDVKL----PHGGSFVIAHSL 783
+ EH++G +GGMDQ SI + A L+ F P + AT K+ PH F+I+++L
Sbjct: 194 SVVSEHYVGVNTGGMDQCASIYGEQNKALLVQFKPKLMATPFKMPVLKPHDMVFLISNTL 253
Query: 784 AESQKAVTAATNYNNRVVECRLASIILGIKLGME-PKEAISKVKTL 918
E+ K TA TNYN RVVE +AS L K +E PKE+ TL
Sbjct: 254 VEANKQETALTNYNLRVVEMAVASEFLAKKFNLELPKESNLHTGTL 299
Score = 93 bits (229), Expect = 6e-018
Identities = 52/144 (36%), Positives = 80/144 (55%), Gaps = 13/144 (9%)
Frame = +1
Query: 1114 KLHQRAAHVYSEARRV-------HGFKDTVDSNLSDEEKLKKLGDLMNESHYSCSVLYEC 1272
K++QR HVYS+A RV H KD+ D ++ + G L+N+S S +
Sbjct: 379 KIYQRTVHVYSDAMRVLQVLKLFHQHKDSDD----PQKFMLAFGRLLNDSQRSEDIYNNS 434
Query: 1273 SCPELEELVKVSRENGALGARLTGAGWGGCTVALVKESGVSQFIAAVKDKYYKKRIEKGV 1452
S PEL E+ K+S NG GAR TGAGWGG V L +++ + A+ ++YYKK+ K
Sbjct: 435 SSPELREVCKISLANGGYGARTTGAGWGGSAVHLTTHDKLAKLVEALTEQYYKKQFPK-- 492
Query: 1453 VKEEDMELYLFASKPSSGAAIFNL 1524
+ + ++ + SKP++G+ I L
Sbjct: 493 ITQSELNAAVVVSKPAAGSCIVQL 516
>sp|P13045|GAL3_YEAST Protein GAL3 OS=Saccharomyces cerevisiae GN=GAL3 PE=1
SV=2
Length = 520
Score = 161 bits (406), Expect = 2e-038
Identities = 102/261 (39%), Positives = 146/261 (55%), Gaps = 17/261 (6%)
Frame = +1
Query: 136 ALKSKFNQAFDASPQLFARSPGRVNLIGEHIDYEGYSVLPMAIRQDTIIAIRKREGSN-E 312
A+ F Q + P ARSPGRVNLIGEHIDY +SVLP+AI D + A++ + N
Sbjct: 25 AVVDAFFQTYHVKPDFIARSPGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPS 84
Query: 313 LRIANVNEKYSMCTY--PAD-PHQEIDLQNHKWGHYFICAYKGFHEYAKS---KGVNVDS 474
+ + N + K++ + P D + ID +W +YF C H Y K + N
Sbjct: 85 ITLTNADPKFAQRKFDLPLDGSYMAIDPSVSEWSNYFKCGLHVAHSYLKKIAPERFNNTP 144
Query: 475 PVGLDVVVDGIVPTGSGLSSSAAFVCSSTIA-IMAVFGENFE--KKELAQLTCECEHHIG 645
VG + +PTG GLSS AF C++ +A I A G+NF+ KK+L ++T EH++G
Sbjct: 145 LVGAQIFCQSDIPTGGGLSS--AFTCAAALATIRANMGKNFDISKKDLTRITAVAEHYVG 202
Query: 646 TQSGGMDQAISIMAKTGFAELIDFNP-VRATDVKLP----HGGSFVIAHSLAESQKAVTA 810
+GGMDQA S+ + A ++F P ++AT K P H SFVIA++L +S K TA
Sbjct: 203 VNNGGMDQATSVYGEEDHALYVEFRPKLKATPFKFPQLKNHEISFVIANTLVKSNKFETA 262
Query: 811 ATNYNNRVVECRLASIILGIK 873
TNYN RV+E +A+ L +
Sbjct: 263 PTNYNLRVIEVTVAANALATR 283
Score = 101 bits (251), Expect = 2e-020
Identities = 57/140 (40%), Positives = 81/140 (57%), Gaps = 7/140 (5%)
Frame = +1
Query: 1114 KLHQRAAHVYSEARRVHGFKDTVDSNL--SDEEKLKKLGDLMNESHYSCSVLYECSCPEL 1287
KL+QRA HVYSE+ RV + S +DE+ G LMNES SC LYECSC E
Sbjct: 381 KLYQRAKHVYSESLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKLYECSCIET 440
Query: 1288 EELVKVSRENGALGARLTGAGWGGCTVALV---KESGVSQFIAAVKDKYYKKRIEKGVVK 1458
++ ++ NG+ G+RLTGAGWGGCT+ LV V Q A+ +K+Y R +
Sbjct: 441 NQICSIALANGSFGSRLTGAGWGGCTIHLVPSGANGNVEQVRKALIEKFYNVRYPD--LT 498
Query: 1459 EEDMELYLFASKPSSGAAIF 1518
+E+++ + SKP+ G ++
Sbjct: 499 DEELKDAIIVSKPALGTCLY 518
>sp|P04385|GAL1_YEAST Galactokinase OS=Saccharomyces cerevisiae GN=GAL1 PE=1
SV=4
Length = 528
Score = 143 bits (359), Expect = 5e-033
Identities = 94/260 (36%), Positives = 141/260 (54%), Gaps = 18/260 (6%)
Frame = +1
Query: 49 EEVTVPIFSSLDHVYGEGSQL-QEAKSRFDALKSKFNQAFDASPQLFARSPGRVNLIGEH 225
EEV VP F+S +L + + ++ KF A+DA P ARSPGRVNLIGEH
Sbjct: 7 EEVIVPEFNS------SAKELPRPLAEKCPSIIKKFISAYDAKPDFVARSPGRVNLIGEH 60
Query: 226 IDYEGYSVLPMAIRQDTIIAIR-KREGSNELRIANVNEKYSMCTY--PAD-PHQEIDLQN 393
IDY +SVLP+AI D + A++ E + + + N + K++ + P D + ID
Sbjct: 61 IDYCDFSVLPLAIDFDMLCAVKVLNEKNPSITLINADPKFAQRKFDLPLDGSYVTIDPSV 120
Query: 394 HKWGHYFICAYKGFHEYAKSKGVN--VDSPV-GLDVVVDGIVPTGSGLSSSAAFVCSSTI 564
W +YF C H + K +P+ GL V +G VPTGSGLSSSAAF+C+ +
Sbjct: 121 SDWSNYFKCGLHVAHSFLKKLAPERFASAPLAGLQVFCEGDVPTGSGLSSSAAFICAVAL 180
Query: 565 AIMAVF---GENFEKKELAQLTCECEHHIGTQSGGMDQAISIMAKTGFAELIDFNP-VRA 732
A++ G + K+ L ++T EH++G +GGMDQA S+ + A ++F P ++A
Sbjct: 181 AVVKANMGPGYHMSKQNLMRITVVAEHYVGVNNGGMDQAASVCGEEDHALYVEFKPQLKA 240
Query: 733 TDVKLPHGGSFVIAHSLAES 792
T K P + I+ +A +
Sbjct: 241 TPFKFPQLKNHEISFVIANT 260
Score = 114 bits (284), Expect = 3e-024
Identities = 66/184 (35%), Positives = 105/184 (57%), Gaps = 17/184 (9%)
Frame = +1
Query: 1000 KEEPYTAEEIEKIV----QEKLPSILNNDPTSLAVLNAATHFKLHQRAAHVYSEARRVHG 1167
K++ ++ +++ + + +E L P VL KL+QRA HVYSE+ RV
Sbjct: 353 KKQGFSVDDVAQSLNCSREEFTRDYLTTSPVRFQVL------KLYQRAKHVYSESLRVLK 406
Query: 1168 FKD--TVDSNLSDEEKLKKLGDLMNESHYSCSVLYECSCPELEELVKVSRENGALGARLT 1341
T S +DE+ K+ G LMNES SC LYECSCPE++++ ++ NG+ G+RLT
Sbjct: 407 AVKLMTTASFTADEDFFKQFGALMNESQASCDKLYECSCPEIDKICSIALSNGSYGSRLT 466
Query: 1342 GAGWGGCTVALV---KESGVSQFIAAVKDKYYKKRIEKGVVKEEDMELYLFASKPSSGAA 1512
GAGWGGCTV LV + + A+ +++YK + K + + ++E + SKP+ G+
Sbjct: 467 GAGWGGCTVHLVPGGPNGNIEKVKEALANEFYKVKYPK--ITDAELENAIIVSKPALGSC 524
Query: 1513 IFNL 1524
++ L
Sbjct: 525 LYEL 528
>sp|P09608|GAL1_KLULA Galactokinase OS=Kluyveromyces lactis GN=GAL1 PE=2 SV=2
Length = 503
Score = 109 bits (271), Expect = 8e-023
Identities = 62/149 (41%), Positives = 85/149 (57%), Gaps = 7/149 (4%)
Frame = +1
Query: 1078 TSLAVLNAATHF---KLHQRAAHVYSEARRVHGFKDTVDSNLSDEEKLKKLGDLMNESHY 1248
T L + N F KL QRA HVYSEA RV K + ++ G LMNES
Sbjct: 357 TELYLTNFPVRFQRLKLFQRAKHVYSEALRV--LKALQLFQKGESNFFEEFGALMNESQE 414
Query: 1249 SCSVLYECSCPELEELVKVSRENGALGARLTGAGWGGCTVALVKESGVSQFIAAVKDKYY 1428
SC LYECSCPE + + +++ +NG+ G+RLTGAGWGGCTV L V +A+ ++YY
Sbjct: 415 SCDKLYECSCPETDSICEIALKNGSFGSRLTGAGWGGCTVHLCSTDTVDSVKSALTEQYY 474
Query: 1429 KKRIEKGVVKEEDMELYLFASKPSSGAAI 1515
R + + E++E + SKPS G+ +
Sbjct: 475 NLRFPE--LTAEELEDAIIISKPSLGSVL 501
>sp|O42821|GAL1_CANPA Galactokinase OS=Candida parapsilosis GN=GAL1 PE=3 SV=1
Length = 504
Score = 87 bits (214), Expect = 3e-016
Identities = 61/183 (33%), Positives = 91/183 (49%), Gaps = 13/183 (7%)
Frame = +1
Query: 988 KEYLKEEPYT----AEEIEKIVQEKLPSILNNDPTSLAVLNAATHFKLHQRAAHVYSEAR 1155
K KE YT EE+ +E L P VL KL++RA HVY E+
Sbjct: 323 KTLTKEGGYTVEQCCEEMGLTPEEFHSRYLKKIPVKFDVL------KLYERALHVYRESL 376
Query: 1156 RVHGFKDTVDSNLSDEEKLKKLGDLMNESHYSCSVLYECSCPELEELVKVSRENGALGAR 1335
RV + + + + L+ G LMNES + +L E S P+L E+ ++ NGA G+R
Sbjct: 377 RVLKTLQLLSTVVDASQFLQTFGSLMNESQHDLDILNESSNPKLNEICSIALANGAYGSR 436
Query: 1336 LTGAGWGGCTVALVKESGVSQFIAAVKDKYYKKRIEKGVVKEEDMELYLFASKPSSGAAI 1515
+TGAGWGG V L + + ++ + YYK+ G+ EE E + SKP++G+ +
Sbjct: 437 VTGAGWGGSIVHLTTTENLPKLTKSL-EAYYKREF-PGITDEEIREA-VIDSKPATGSCL 493
Query: 1516 FNL 1524
L
Sbjct: 494 VKL 496
>sp|P56091|GAL1_CANAL Galactokinase OS=Candida albicans GN=GAL1 PE=3 SV=1
Length = 515
Score = 77 bits (188), Expect = 3e-013
Identities = 49/141 (34%), Positives = 72/141 (51%), Gaps = 8/141 (5%)
Frame = +1
Query: 1114 KLHQRAAHVYSEARRV-------HGFKDTVDSNLSDEEKLKKLGDLMNESHYSCSVLYEC 1272
KL+QRA HVY E+ RV + + +S DE L K G+LMN+S L E
Sbjct: 369 KLYQRAKHVYQESLRVLETLKLLSTTQTSSNSKDDDESFLVKFGELMNQSQSDLDKLNES 428
Query: 1273 SCPELEELVKVSRENGALGARLTGAGWGGCTVALVKESGVSQFIAAVKDKYYKKRIEKGV 1452
S +L ++ ++ +NG+ G+R+TGAGWGG V L Q I + YY+ +
Sbjct: 429 SNDKLNKICSIALQNGSYGSRITGAGWGGSIVHLTTLDKSKQLIQGLIKNYYQLEF-PSI 487
Query: 1453 VKEEDMELYLFASKPSSGAAI 1515
+E + + SKPS G+ I
Sbjct: 488 KLDELLNDAIIDSKPSMGSCI 508
>sp|C4LB24|GAL1_TOLAT Galactokinase OS=Tolumonas auensis (strain DSM 9187 / TA4)
GN=galK PE=3 SV=1
Length = 384
Score = 65 bits (157), Expect = 1e-009
Identities = 36/110 (32%), Positives = 61/110 (55%), Gaps = 14/110 (12%)
Frame = +1
Query: 151 FNQAFDASPQLFARSPGRVNLIGEHIDYEGYSVLPMAIRQDTIIAIRKREGSNELRI--- 321
F +F P L+ R+PGRVNLIGEH DY VLP AI +T++A+++R+ + +
Sbjct: 11 FQNSFGCEPDLYVRAPGRVNLIGEHTDYNDGFVLPCAIDYETVVALQRRDDDKVVVVAAD 70
Query: 322 -ANVNEKYSMCTYPADPHQEIDLQNHKWGHYFICAYKGFHEYAKSKGVNV 468
AN +++S+ + P + H + W +Y +G +Y KG+++
Sbjct: 71 YANQRDEFSL-SQPIEAHAD-----QLWSNYI----RGVVKYLLEKGLSL 110
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,413,996,008
Number of Sequences: 518415
Number of Extensions: 65413996008
Number of Successful Extensions: 465124098
Number of sequences better than 0.0: 0
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