BLASTX 7.6.2
Query= UN16208 /QuerySize=1259
(1258 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q60HE2|ODO1_MACFA 2-oxoglutarate dehydrogenase, mitochondrial... 361 1e-098
sp|Q02218|ODO1_HUMAN 2-oxoglutarate dehydrogenase, mitochondrial... 360 1e-098
sp|Q5RCB8|ODO1_PONAB 2-oxoglutarate dehydrogenase, mitochondrial... 358 5e-098
sp|Q148N0|ODO1_BOVIN 2-oxoglutarate dehydrogenase, mitochondrial... 357 1e-097
sp|Q5XI78|ODO1_RAT 2-oxoglutarate dehydrogenase, mitochondrial O... 355 4e-097
sp|Q60597|ODO1_MOUSE 2-oxoglutarate dehydrogenase, mitochondrial... 354 1e-096
sp|Q623T0|ODO1_CAEBR 2-oxoglutarate dehydrogenase, mitochondrial... 327 2e-088
sp|O61199|ODO1_CAEEL 2-oxoglutarate dehydrogenase, mitochondrial... 324 8e-088
sp|Q54JE4|ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial... 269 3e-071
sp|O74378|ODO1_SCHPO 2-oxoglutarate dehydrogenase, mitochondrial... 258 7e-068
sp|Q9ULD0|OGDHL_HUMAN 2-oxoglutarate dehydrogenase-like, mitocho... 253 3e-066
sp|Q68EW0|OGDHL_XENLA 2-oxoglutarate dehydrogenase-like, mitocho... 252 5e-066
sp|P20967|ODO1_YEAST 2-oxoglutarate dehydrogenase, mitochondrial... 250 2e-065
sp|Q5R9L8|OGDHL_PONAB 2-oxoglutarate dehydrogenase-like, mitocho... 250 2e-065
sp|Q6P6Z8|ODO1_XENLA 2-oxoglutarate dehydrogenase, mitochondrial... 250 2e-065
sp|Q1RHI4|ODO1_RICBR 2-oxoglutarate dehydrogenase E1 component O... 184 1e-045
sp|Q92J42|ODO1_RICCN 2-oxoglutarate dehydrogenase E1 component O... 183 4e-045
sp|Q68XI7|ODO1_RICTY 2-oxoglutarate dehydrogenase E1 component O... 182 5e-045
sp|Q8CUL8|ODO1_OCEIH 2-oxoglutarate dehydrogenase E1 component O... 181 9e-045
sp|A6WXF0|ODO1_OCHA4 2-oxoglutarate dehydrogenase E1 component O... 181 9e-045
>sp|Q60HE2|ODO1_MACFA 2-oxoglutarate dehydrogenase, mitochondrial OS=Macaca
fascicularis GN=OGDH PE=2 SV=1
Length = 1023
Score = 361 bits (924), Expect = 1e-098
Identities = 183/350 (52%), Positives = 239/350 (68%), Gaps = 21/350 (6%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYC-PLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSME 181
VERGTFSHRH VLHDQ + C P++HL NQ P +TV NSSLSE+GVLGFELG++M
Sbjct: 678 VERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP--YTVCNSSLSEYGVLGFELGFAMA 735
Query: 182 SPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARL 361
SPN+LVLWEAQFGDF N AQ I DQFI G+AKW+RQ G+V+LLPHG +G GPEHSSAR
Sbjct: 736 SPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARP 795
Query: 362 ERYLQMSDDNPYVIPDMEPTL--RKQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLI 535
ER+LQM +D+P V+PD++ Q+ +CNW +VN +TP N+FHVLRRQ+ FRKPLI
Sbjct: 796 ERFLQMCNDDPDVLPDLKEANFDINQLHDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLI 855
Query: 536 VMAPKNLLRHKDCKSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSDLEEGIRRLVLCS 715
+ PK+LLRH + +S+ E GT F+R+I + + E ++RL+ C+
Sbjct: 856 IFTPKSLLRHPEARSSFDEM----------LPGTHFQRVIPEDGPAAQNPENVKRLLFCT 905
Query: 716 GKVYYELDDERK-KVGASDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEAMNMGA 892
GKVYY+L ERK + VAI R+EQL PFP+DL+ +E+++YPNAE+ WCQEE N G
Sbjct: 906 GKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPNAELAWCQEEHKNQGY 965
Query: 893 FSYITPRLWTAMRSLGRGDMEDIKYVGRGPSAATATGFYTFHVKEQAELV 1042
+ Y+ PRL T + + + Y GR P+AA ATG H+ E L+
Sbjct: 966 YDYVKPRLRTTI-----SRAKPVWYAGRDPAAAPATGNKKTHLTELQRLL 1010
>sp|Q02218|ODO1_HUMAN 2-oxoglutarate dehydrogenase, mitochondrial OS=Homo
sapiens GN=OGDH PE=1 SV=3
Length = 1023
Score = 360 bits (923), Expect = 1e-098
Identities = 183/350 (52%), Positives = 239/350 (68%), Gaps = 21/350 (6%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYC-PLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSME 181
VERGTFSHRH VLHDQ + C P++HL NQ P +TV NSSLSE+GVLGFELG++M
Sbjct: 678 VERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP--YTVCNSSLSEYGVLGFELGFAMA 735
Query: 182 SPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARL 361
SPN+LVLWEAQFGDF N AQ I DQFI G+AKW+RQ G+V+LLPHG +G GPEHSSAR
Sbjct: 736 SPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARP 795
Query: 362 ERYLQMSDDNPYVIPDMEPTL--RKQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLI 535
ER+LQM +D+P V+PD++ Q+ +CNW +VN +TP N+FHVLRRQ+ FRKPLI
Sbjct: 796 ERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLI 855
Query: 536 VMAPKNLLRHKDCKSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSDLEEGIRRLVLCS 715
+ PK+LLRH + +S+ E GT F+R+I + + E ++RL+ C+
Sbjct: 856 IFTPKSLLRHPEARSSFDEM----------LPGTHFQRVIPEDGPAAQNPENVKRLLFCT 905
Query: 716 GKVYYELDDERK-KVGASDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEAMNMGA 892
GKVYY+L ERK + VAI R+EQL PFP+DL+ +E+++YPNAE+ WCQEE N G
Sbjct: 906 GKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPNAELAWCQEEHKNQGY 965
Query: 893 FSYITPRLWTAMRSLGRGDMEDIKYVGRGPSAATATGFYTFHVKEQAELV 1042
+ Y+ PRL T + + + Y GR P+AA ATG H+ E L+
Sbjct: 966 YDYVKPRLRTTI-----SRAKPVWYAGRDPAAAPATGNKKTHLTELQRLL 1010
>sp|Q5RCB8|ODO1_PONAB 2-oxoglutarate dehydrogenase, mitochondrial OS=Pongo
abelii GN=OGDH PE=2 SV=1
Length = 1023
Score = 358 bits (918), Expect = 5e-098
Identities = 182/350 (52%), Positives = 239/350 (68%), Gaps = 21/350 (6%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYC-PLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSME 181
VERGTFSHRH VLHDQ + C P++HL NQ P +TV NSSLSE+GVLGFELG++M
Sbjct: 678 VERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP--YTVCNSSLSEYGVLGFELGFAMA 735
Query: 182 SPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARL 361
SPN+LVLWEAQFGDF N AQ I DQFI G+AKW+RQ G+V+LLPHG +G GPEHSSAR
Sbjct: 736 SPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARP 795
Query: 362 ERYLQMSDDNPYVIPDMEPTL--RKQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLI 535
ER+LQM +D+P V+PD++ Q+ +CNW +VN +TP N+FHVLRRQ+ FRKPLI
Sbjct: 796 ERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLI 855
Query: 536 VMAPKNLLRHKDCKSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSDLEEGIRRLVLCS 715
+ PK+LLRH + +S+ E GT F+R+I + + E ++RL+ C+
Sbjct: 856 IFTPKSLLRHPEARSSFDEM----------LPGTHFQRVIPEDGPAAQNPENVKRLLFCT 905
Query: 716 GKVYYELDDERK-KVGASDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEAMNMGA 892
GKVYY+L ERK + VAI R+EQL PFP+DL+ +E+++YP+AE+ WCQEE N G
Sbjct: 906 GKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPSAELAWCQEEHKNQGY 965
Query: 893 FSYITPRLWTAMRSLGRGDMEDIKYVGRGPSAATATGFYTFHVKEQAELV 1042
+ Y+ PRL T + + + Y GR P+AA ATG H+ E L+
Sbjct: 966 YDYVKPRLRTTI-----SRAKPVWYAGRDPAAAPATGNKKTHLTELQRLL 1010
>sp|Q148N0|ODO1_BOVIN 2-oxoglutarate dehydrogenase, mitochondrial OS=Bos taurus
GN=OGDH PE=2 SV=1
Length = 1023
Score = 357 bits (915), Expect = 1e-097
Identities = 182/350 (52%), Positives = 238/350 (68%), Gaps = 21/350 (6%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYC-PLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSME 181
VERGTFSHRH VLHDQ + C P++HL NQ P +TV NSSLSE+GVLGFELG++M
Sbjct: 678 VERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP--YTVCNSSLSEYGVLGFELGFAMA 735
Query: 182 SPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARL 361
SPN+LVLWEAQFGDF N AQ I DQFI G+AKW+RQ G+V+LLPHG +G GPEHSSAR
Sbjct: 736 SPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARP 795
Query: 362 ERYLQMSDDNPYVIPDMEPTL--RKQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLI 535
ER+LQM +D+P V+PD++ Q+ +CNW +VN +TP N+FHVLRRQ+ FRKPLI
Sbjct: 796 ERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLI 855
Query: 536 VMAPKNLLRHKDCKSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSDLEEGIRRLVLCS 715
+ PK+LLRH + +SN E GT F+R+I + + ++RL+ C+
Sbjct: 856 IFTPKSLLRHPEARSNFDEM----------LPGTHFQRVIPEDGPAAQNPGNVKRLLFCT 905
Query: 716 GKVYYELDDERK-KVGASDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEAMNMGA 892
GKVYY+L ERK + VAI R+EQL PFP+DL+ +E+++YP+AE+ WCQEE N G
Sbjct: 906 GKVYYDLTRERKARDMVEQVAITRIEQLSPFPFDLLLQEVQKYPSAELAWCQEEHKNQGY 965
Query: 893 FSYITPRLWTAMRSLGRGDMEDIKYVGRGPSAATATGFYTFHVKEQAELV 1042
+ Y+ PRL T + + + Y GR P+AA ATG H+ E L+
Sbjct: 966 YDYVKPRLRTTI-----SRAKPVWYAGRDPAAAPATGNKKTHLTELQRLL 1010
>sp|Q5XI78|ODO1_RAT 2-oxoglutarate dehydrogenase, mitochondrial OS=Rattus
norvegicus GN=Ogdh PE=1 SV=1
Length = 1023
Score = 355 bits (910), Expect = 4e-097
Identities = 182/345 (52%), Positives = 238/345 (68%), Gaps = 21/345 (6%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYC-PLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSME 181
VERGTFSHRH VLHDQ + C P++HL NQ P +TV NSSLSE+GVLGFELG++M
Sbjct: 678 VERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP--YTVCNSSLSEYGVLGFELGFAMA 735
Query: 182 SPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARL 361
SPN+LVLWEAQFGDF N AQ I DQFI G+AKW+RQ G+V+LLPHG +G GPEHSSAR
Sbjct: 736 SPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARP 795
Query: 362 ERYLQMSDDNPYVIPDM--EPTLRKQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLI 535
ER+LQM +D+P V+P++ E Q+ +CNW +VN +TP N+FHVLRRQ+ FRKPLI
Sbjct: 796 ERFLQMCNDDPDVLPNLQEENFDISQLYDCNWIVVNCSTPGNFFHVLRRQILLPFRKPLI 855
Query: 536 VMAPKNLLRHKDCKSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSDLEEGIRRLVLCS 715
V PK+LLRH + +++ E GT F+R+I + + + ++RL+ C+
Sbjct: 856 VFTPKSLLRHPEARTSFDEM----------LPGTHFQRVIPEDGPAAQNPDKVKRLLFCT 905
Query: 716 GKVYYELDDERK-KVGASDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEAMNMGA 892
GKVYY+L ERK + A +VAI R+EQL PFP+DL+ +E ++YPNAE+ WCQEE N G
Sbjct: 906 GKVYYDLTRERKARDMAEEVAITRIEQLSPFPFDLLLKEAQKYPNAELAWCQEEHKNQGY 965
Query: 893 FSYITPRLWTAMRSLGRGDMEDIKYVGRGPSAATATGFYTFHVKE 1027
+ Y+ PRL T + + + Y GR P+AA ATG H+ E
Sbjct: 966 YDYVKPRLRTTI-----DRAKPVWYAGRDPAAAPATGNKKTHLTE 1005
>sp|Q60597|ODO1_MOUSE 2-oxoglutarate dehydrogenase, mitochondrial OS=Mus
musculus GN=Ogdh PE=1 SV=3
Length = 1023
Score = 354 bits (907), Expect = 1e-096
Identities = 182/345 (52%), Positives = 236/345 (68%), Gaps = 21/345 (6%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYC-PLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSME 181
VERGTFSHRH VLHDQ + C P++HL NQ P +TV NSSLSE+GVLGFELG++M
Sbjct: 678 VERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP--YTVCNSSLSEYGVLGFELGFAMA 735
Query: 182 SPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARL 361
SPN+LVLWEAQFGDF N AQ I DQFI G+AKW+RQ G+V+LLPHG +G GPEHSSAR
Sbjct: 736 SPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARP 795
Query: 362 ERYLQMSDDNPYVIPDM--EPTLRKQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLI 535
ER+LQM +D+P V+PD+ E Q+ +CNW +VN +TP N+FHVLRRQ+ FRKPLI
Sbjct: 796 ERFLQMCNDDPDVLPDLQEENFDINQLYDCNWIVVNCSTPGNFFHVLRRQILLPFRKPLI 855
Query: 536 VMAPKNLLRHKDCKSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSDLEEGIRRLVLCS 715
V PK+LLRH + +++ E GT F+R+I + + ++RL+ C+
Sbjct: 856 VFTPKSLLRHPEARTSFDEM----------LPGTHFQRVIPENGPAAQDPHKVKRLLFCT 905
Query: 716 GKVYYELDDERK-KVGASDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEAMNMGA 892
GKVYY+L ERK + +VAI R+EQL PFP+DL+ +E ++YPNAE+ WCQEE N G
Sbjct: 906 GKVYYDLTRERKARNMEEEVAITRIEQLSPFPFDLLLKEAQKYPNAELAWCQEEHKNQGY 965
Query: 893 FSYITPRLWTAMRSLGRGDMEDIKYVGRGPSAATATGFYTFHVKE 1027
+ Y+ PRL T + + + Y GR P+AA ATG H+ E
Sbjct: 966 YDYVKPRLRTTI-----DRAKPVWYAGRDPAAAPATGNKKTHLTE 1005
>sp|Q623T0|ODO1_CAEBR 2-oxoglutarate dehydrogenase, mitochondrial
OS=Caenorhabditis briggsae GN=CBG01737 PE=3 SV=1
Length = 1027
Score = 327 bits (836), Expect = 2e-088
Identities = 168/322 (52%), Positives = 227/322 (70%), Gaps = 24/322 (7%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEE-YCPLDHLVMNQDPE-MFTVSNSSLSEFGVLGFELGYSM 178
VERGTFSHRH VLHDQ+ ++ Y PL+ L DP+ +TV NSSLSE+ VLGFELGYSM
Sbjct: 676 VERGTFSHRHHVLHDQKVDQKIYNPLNDLA---DPQGEYTVCNSSLSEYAVLGFELGYSM 732
Query: 179 ESPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSAR 358
PNSLV+WEAQFGDF+N AQ I DQF+SSG++KW+RQ+GLV+LLPHGY+G GPEHSSAR
Sbjct: 733 VDPNSLVIWEAQFGDFSNTAQCIIDQFVSSGQSKWIRQSGLVMLLPHGYEGMGPEHSSAR 792
Query: 359 LERYLQMSDDNPYVIPDMEPTL------RKQIQECNWQIVNATTPANYFHVLRRQLHRDF 520
ER+LQM +++ + D++ +Q+ + NW + N TTPAN +H+LRRQ+ F
Sbjct: 793 PERFLQMCNEDDEI--DLDKIAFGGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPF 850
Query: 521 RKPLIVMAPKNLLRHKDCKSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSDLEEGIRR 700
RKP +V +PK+LLRH +S + +F + G+ F+R+I + S ++R
Sbjct: 851 RKPAVVFSPKSLLRHPMARSPVEDF----------QSGSNFQRIIPETGAPSQNPPNVQR 900
Query: 701 LVLCSGKVYYELDDERKKVG-ASDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEA 877
LV C+GKVYY++ RK VG +DVA+ RVEQL PFPYDL+Q+E ++Y AEI+W QEE
Sbjct: 901 LVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEIIWAQEEH 960
Query: 878 MNMGAFSYITPRLWTAMRSLGR 943
NMGA+S++ PR+ + + GR
Sbjct: 961 KNMGAWSFVQPRINSLLSIDGR 982
>sp|O61199|ODO1_CAEEL 2-oxoglutarate dehydrogenase, mitochondrial
OS=Caenorhabditis elegans GN=T22B11.5 PE=1 SV=2
Length = 1029
Score = 324 bits (830), Expect = 8e-088
Identities = 167/321 (52%), Positives = 225/321 (70%), Gaps = 22/321 (6%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEE-YCPLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSME 181
V+RGTFSHRH VLHDQ+ ++ Y PL+ L Q +TV NSSLSE+ VLGFELGYSM
Sbjct: 678 VQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGE--YTVCNSSLSEYAVLGFELGYSMV 735
Query: 182 SPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARL 361
PNSLV+WEAQFGDF+N AQ I DQFISSG++KW+RQ+GLV+LLPHGY+G GPEHSSAR
Sbjct: 736 DPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARP 795
Query: 362 ERYLQMSDDNPYVIPDMEPTL------RKQIQECNWQIVNATTPANYFHVLRRQLHRDFR 523
ER+LQM +++ + D+E +Q+ + NW + N TTPAN +H+LRRQ+ FR
Sbjct: 796 ERFLQMCNEDDEI--DLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFR 853
Query: 524 KPLIVMAPKNLLRHKDCKSNLSEFDDVQGHPGFDKQGTRFKRLIKDQNDHSDLEEGIRRL 703
KP +V +PK+LLRH +S + +F + G+ F+R+I + S ++R+
Sbjct: 854 KPAVVFSPKSLLRHPMARSPVEDF----------QSGSNFQRVIPETGAPSQNPPDVKRV 903
Query: 704 VLCSGKVYYELDDERKKVG-ASDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEAM 880
V C+GKVYY++ RK VG +DVA+ RVEQL PFPYDL+Q+E ++Y AEI+W QEE
Sbjct: 904 VFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHK 963
Query: 881 NMGAFSYITPRLWTAMRSLGR 943
NMGA+S++ PR+ + + GR
Sbjct: 964 NMGAWSFVQPRINSLLSIDGR 984
>sp|Q54JE4|ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial
OS=Dictyostelium discoideum GN=ogdh PE=3 SV=1
Length = 1013
Score = 269 bits (687), Expect = 3e-071
Identities = 127/200 (63%), Positives = 152/200 (76%), Gaps = 3/200 (1%)
Frame = +2
Query: 11 RGTFSHRHSVLHDQETGEEYCPLDHLVM---NQDPEMFTVSNSSLSEFGVLGFELGYSME 181
RGTFSHRH+V HDQ+T + Y PL L +D F SNSSLSEF VLGFELGYS+E
Sbjct: 668 RGTFSHRHAVWHDQKTDQTYAPLTKLATALGKKDAAEFVASNSSLSEFAVLGFELGYSLE 727
Query: 182 SPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARL 361
+P++L+LWEAQFGDF+NGAQVI DQFISSGE KW+RQ+GL +LLPHGYDG GPEHSS R+
Sbjct: 728 NPDALILWEAQFGDFSNGAQVIIDQFISSGEQKWMRQSGLTMLLPHGYDGAGPEHSSCRI 787
Query: 362 ERYLQMSDDNPYVIPDMEPTLRKQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLIVM 541
ERYLQ+ D +P IP E RKQ Q CN Q++N +TP NYFH LRRQ+HRDFRKPL++
Sbjct: 788 ERYLQLCDSDPNKIPPKEEAERKQSQHCNMQVLNCSTPVNYFHALRRQVHRDFRKPLVIA 847
Query: 542 APKNLLRHKDCKSNLSEFDD 601
PK LLR++ S EF +
Sbjct: 848 TPKYLLRYEKSFSTAKEFSN 867
>sp|O74378|ODO1_SCHPO 2-oxoglutarate dehydrogenase, mitochondrial
OS=Schizosaccharomyces pombe GN=kgd1 PE=2 SV=1
Length = 1009
Score = 258 bits (658), Expect = 7e-068
Identities = 122/202 (60%), Positives = 153/202 (75%), Gaps = 3/202 (1%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYCPLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSMES 184
VERGTFS RH+VLHDQ + Y PL+HL NQ F + NSSLSE+GVLGFE GYS+ S
Sbjct: 671 VERGTFSQRHAVLHDQSSENVYIPLNHLSPNQ--ASFVIRNSSLSEYGVLGFEYGYSLSS 728
Query: 185 PNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARLE 364
PN+LV+WEAQFGDFAN AQ I DQFI++GE KWL++TG+V+ LPHGYDGQGPEHSSAR+E
Sbjct: 729 PNALVVWEAQFGDFANNAQCIIDQFIAAGETKWLQRTGIVLSLPHGYDGQGPEHSSARME 788
Query: 365 RYLQMSDDNPYVIPDMEPTLRKQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLIVMA 544
RYLQ+ +++P P E L++Q Q+CN Q + T P+ YFH LRR +HR FRKPL++
Sbjct: 789 RYLQLCNEDPREFPS-EEKLQRQHQDCNIQAIYVTKPSQYFHALRRNIHRQFRKPLVIFF 847
Query: 545 PKNLLRHKDCKSNLSEFDDVQG 610
K+LLRH +S + EFD+ G
Sbjct: 848 SKSLLRHPAARSTIDEFDEKHG 869
>sp|Q9ULD0|OGDHL_HUMAN 2-oxoglutarate dehydrogenase-like, mitochondrial OS=Homo
sapiens GN=OGDHL PE=2 SV=3
Length = 1010
Score = 253 bits (644), Expect = 3e-066
Identities = 124/198 (62%), Positives = 150/198 (75%), Gaps = 4/198 (2%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYC-PLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSME 181
VERGTFSHRH VLHDQE C P++HL +Q P +TV NSSLSE+GVLGFELGY+M
Sbjct: 665 VERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAP--YTVCNSSLSEYGVLGFELGYAMA 722
Query: 182 SPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARL 361
SPN+LVLWEAQFGDF N AQ I DQFIS+G+AKW+R G+V+LLPHG +G GPEHSSAR
Sbjct: 723 SPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARP 782
Query: 362 ERYLQMSDDNPYVIPDMEPTLR-KQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLIV 538
ER+LQMS+D+ P Q+ +CNW +VN +TPANYFHVLRRQ+ FRKPLI+
Sbjct: 783 ERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLII 842
Query: 539 MAPKNLLRHKDCKSNLSE 592
PK+LLRH + KS+ +
Sbjct: 843 FTPKSLLRHPEAKSSFDQ 860
>sp|Q68EW0|OGDHL_XENLA 2-oxoglutarate dehydrogenase-like, mitochondrial
OS=Xenopus laevis GN=ogdhl PE=2 SV=1
Length = 1018
Score = 252 bits (642), Expect = 5e-066
Identities = 127/210 (60%), Positives = 156/210 (74%), Gaps = 7/210 (3%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYC-PLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSME 181
VERGTFSHRH VLHDQE C P++HL NQ P +TV NSSLSE+GVLGFELG++M
Sbjct: 673 VERGTFSHRHHVLHDQEVDRWTCVPMNHLWPNQAP--YTVCNSSLSEYGVLGFELGFAMA 730
Query: 182 SPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARL 361
SPN+LVLWEAQFGDF N AQ I DQFISSG+AKW+R G+V+LLPHG +G GPEHSSAR
Sbjct: 731 SPNALVLWEAQFGDFYNTAQCIIDQFISSGQAKWVRHNGIVLLLPHGMEGMGPEHSSARP 790
Query: 362 ERYLQMSDDNPYVIPDMEPTLR-KQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLIV 538
ER+LQMS+D+ P+ Q+ +CNW +VN + PA+YFHVLRRQ+ FRKPLI+
Sbjct: 791 ERFLQMSNDDSDAYPEFTQDFDVSQLFDCNWIVVNCSNPASYFHVLRRQILLPFRKPLII 850
Query: 539 MAPKNLLRHKDCKSNLSEFDDVQGHPGFDK 628
PK+LLRH + KS+ FDD++ F +
Sbjct: 851 FTPKSLLRHPEAKSS---FDDMKTGTNFQR 877
>sp|P20967|ODO1_YEAST 2-oxoglutarate dehydrogenase, mitochondrial
OS=Saccharomyces cerevisiae GN=KGD1 PE=1 SV=2
Length = 1014
Score = 250 bits (638), Expect = 2e-065
Identities = 121/199 (60%), Positives = 154/199 (77%), Gaps = 3/199 (1%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYCPLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSMES 184
VERGTFS RH+VLHDQ++ Y PL +N + FT++NSSLSE+GV+GFE GYS+ S
Sbjct: 673 VERGTFSQRHAVLHDQQSEAIYTPLS--TLNNEKADFTIANSSLSEYGVMGFEYGYSLTS 730
Query: 185 PNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARLE 364
P+ LV+WEAQFGDFAN AQVI DQFI+ GE KW +++GLV+ LPHGYDGQGPEHSS RLE
Sbjct: 731 PDYLVMWEAQFGDFANTAQVIIDQFIAGGEQKWKQRSGLVLSLPHGYDGQGPEHSSGRLE 790
Query: 365 RYLQMSDDNPYVIPDMEPTLRKQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLIVMA 544
R+LQ+++++P P E L++Q Q+CN+Q+V TTPAN FH+LRRQ HR FRKPL +
Sbjct: 791 RFLQLANEDPRYFPS-EEKLQRQHQDCNFQVVYPTTPANLFHILRRQQHRQFRKPLALFF 849
Query: 545 PKNLLRHKDCKSNLSEFDD 601
K LLRH +S+LSEF +
Sbjct: 850 SKQLLRHPLARSSLSEFTE 868
>sp|Q5R9L8|OGDHL_PONAB 2-oxoglutarate dehydrogenase-like, mitochondrial OS=Pongo
abelii GN=OGDHL PE=2 SV=2
Length = 1010
Score = 250 bits (638), Expect = 2e-065
Identities = 123/198 (62%), Positives = 149/198 (75%), Gaps = 4/198 (2%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYC-PLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSME 181
VERGTFSHRH VLHDQE C P++HL +Q P +TV NSSLSE+GVLGFELGY+M
Sbjct: 665 VERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAP--YTVCNSSLSEYGVLGFELGYAMA 722
Query: 182 SPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARL 361
SPN+LVLWEAQFGDF N AQ I DQFIS+G+AKW+R G+V+LLPHG +G GPEHSSAR
Sbjct: 723 SPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARP 782
Query: 362 ERYLQMSDDNPYVIPDMEPTLR-KQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLIV 538
ER+LQMS+D+ P Q+ +CNW +VN +TPANYFHVLRRQ+ FRKPLI+
Sbjct: 783 ERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLII 842
Query: 539 MAPKNLLRHKDCKSNLSE 592
PK+LLRH + K + +
Sbjct: 843 FTPKSLLRHPEAKFSFDQ 860
>sp|Q6P6Z8|ODO1_XENLA 2-oxoglutarate dehydrogenase, mitochondrial OS=Xenopus
laevis GN=ogdh PE=2 SV=1
Length = 1021
Score = 250 bits (637), Expect = 2e-065
Identities = 125/202 (61%), Positives = 154/202 (76%), Gaps = 7/202 (3%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYC-PLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSME 181
VERGTFSHRH VLHDQ + C P++HL NQ P +TV NSSLSE+GVLGFELG++M
Sbjct: 677 VERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP--YTVCNSSLSEYGVLGFELGFAMA 734
Query: 182 SPNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARL 361
SPN+LVLWEAQFGDF N AQ I DQF+ G+AKW+RQ G+V+LLPHG +G GPEHSSAR
Sbjct: 735 SPNALVLWEAQFGDFHNTAQCIIDQFVCPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARP 794
Query: 362 ERYLQMSDDNPYVIPD-MEPTLRKQIQECNWQIVNATTPANYFHVLRRQLHRDFRKPLIV 538
ER+LQM +D+P V P E Q+ +CNW +VN +TPAN+FHV+RRQ+ FRKPLIV
Sbjct: 795 ERFLQMCNDDPDVWPKASEDFAVGQLYDCNWIVVNCSTPANFFHVIRRQILLPFRKPLIV 854
Query: 539 MAPKNLLRHKDCKSNLSEFDDV 604
PK+LLRH + +S+ FDD+
Sbjct: 855 FTPKSLLRHPEARSS---FDDM 873
>sp|Q1RHI4|ODO1_RICBR 2-oxoglutarate dehydrogenase E1 component OS=Rickettsia
bellii (strain RML369-C) GN=sucA PE=3 SV=1
Length = 927
Score = 184 bits (467), Expect = 1e-045
Identities = 93/148 (62%), Positives = 116/148 (78%), Gaps = 8/148 (5%)
Frame = +2
Query: 11 RGTFSHRHSVLHDQETGEEYCPLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSMESPN 190
RGTFSHRHSVLH+Q Y PL++L +++ + V++S+LSE+ VLGFE GYS+ +P
Sbjct: 612 RGTFSHRHSVLHNQVDDTTYIPLNNL--SKEQATYEVADSNLSEYAVLGFEYGYSLANPK 669
Query: 191 SLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARLERY 370
+LVLWEAQFGDFANGAQ+IFDQFISS E KWLR +GLVVLLPHG++GQGPEHSSARLER+
Sbjct: 670 NLVLWEAQFGDFANGAQIIFDQFISSSETKWLRMSGLVVLLPHGFEGQGPEHSSARLERF 729
Query: 371 LQM-SDDNPYVIPDMEPT-----LRKQI 436
LQ+ ++DN YV P LR+QI
Sbjct: 730 LQLAAEDNMYVTYPTTPASIFHLLRRQI 757
>sp|Q92J42|ODO1_RICCN 2-oxoglutarate dehydrogenase E1 component OS=Rickettsia
conorii GN=sucA PE=3 SV=1
Length = 928
Score = 183 bits (462), Expect = 4e-045
Identities = 92/148 (62%), Positives = 116/148 (78%), Gaps = 8/148 (5%)
Frame = +2
Query: 11 RGTFSHRHSVLHDQETGEEYCPLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSMESPN 190
RGTFSHRHSVLH+Q G Y PL++L +++ + V++S+LSE+ VLGFE GYS+ +P
Sbjct: 614 RGTFSHRHSVLHNQIDGTTYIPLNNL--SKEQAKYEVADSNLSEYAVLGFEYGYSLANPK 671
Query: 191 SLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARLERY 370
+LVLWEAQFGDFANGAQ+IFDQFISS E KWLR +GLVVLLPH ++GQGPEHSSARLER+
Sbjct: 672 NLVLWEAQFGDFANGAQIIFDQFISSSETKWLRMSGLVVLLPHAFEGQGPEHSSARLERF 731
Query: 371 LQM-SDDNPYVIPDMEPT-----LRKQI 436
LQ+ +++N YV P LR+QI
Sbjct: 732 LQLAAENNMYVTYPTTPASIFHLLRRQI 759
>sp|Q68XI7|ODO1_RICTY 2-oxoglutarate dehydrogenase E1 component OS=Rickettsia
typhi GN=sucA PE=3 SV=1
Length = 933
Score = 182 bits (461), Expect = 5e-045
Identities = 92/151 (60%), Positives = 114/151 (75%), Gaps = 8/151 (5%)
Frame = +2
Query: 8 ERGTFSHRHSVLHDQETGEEYCPLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSMESP 187
ERGTFSHRHS+LH+Q Y PL++L Q + V+NS+L+E+ VLGFE GYS+ SP
Sbjct: 614 ERGTFSHRHSILHNQIDDTTYIPLNNLSKTQ--AQYEVANSNLAEYAVLGFEYGYSLASP 671
Query: 188 NSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARLER 367
+LVLWEAQFGDFANGAQ+IFDQFISS KWLR +GLVVLLPH ++GQGPEHSSARLER
Sbjct: 672 KNLVLWEAQFGDFANGAQIIFDQFISSSATKWLRMSGLVVLLPHAFEGQGPEHSSARLER 731
Query: 368 YLQM-SDDNPYVIPDMEPT-----LRKQIQE 442
+LQ+ +++N Y+ P LR+QI E
Sbjct: 732 FLQLAAEENMYITYPTTPASIFHLLRRQILE 762
>sp|Q8CUL8|ODO1_OCEIH 2-oxoglutarate dehydrogenase E1 component
OS=Oceanobacillus iheyensis GN=odhA PE=3 SV=1
Length = 953
Score = 181 bits (459), Expect = 9e-045
Identities = 87/135 (64%), Positives = 108/135 (80%), Gaps = 2/135 (1%)
Frame = +2
Query: 8 ERGTFSHRHSVLHDQETGEEYCPLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSMESP 187
ERGTF+HRH VLHD ETGE+Y PL L + F V NS LSE GVLGFE GYS++SP
Sbjct: 623 ERGTFAHRHIVLHDVETGEKYSPLHGL--SDVEASFDVRNSPLSEAGVLGFEYGYSVQSP 680
Query: 188 NSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARLER 367
++LV+WEAQFGDFAN QVIFDQFISS AKW ++ +V+LLPHGY+GQGPEHSSARLER
Sbjct: 681 DTLVIWEAQFGDFANAGQVIFDQFISSARAKWGEKSNMVLLLPHGYEGQGPEHSSARLER 740
Query: 368 YLQMSDDNPYVIPDM 412
+LQM+ +N +++ ++
Sbjct: 741 FLQMAAENNWIVANV 755
>sp|A6WXF0|ODO1_OCHA4 2-oxoglutarate dehydrogenase E1 component OS=Ochrobactrum
anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168) GN=sucA PE=3 SV=1
Length = 1001
Score = 181 bits (459), Expect = 9e-045
Identities = 94/151 (62%), Positives = 113/151 (74%), Gaps = 8/151 (5%)
Frame = +2
Query: 5 VERGTFSHRHSVLHDQETGEEYCPLDHLVMNQDPEMFTVSNSSLSEFGVLGFELGYSMES 184
VERGTFS RH+VL+DQET Y PL+++ Q ++ NS LSE VLG+E GYS+
Sbjct: 674 VERGTFSQRHTVLYDQETQNRYIPLNNIQKGQ--AIYEAINSMLSEEAVLGYEYGYSLSD 731
Query: 185 PNSLVLWEAQFGDFANGAQVIFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARLE 364
P +LVLWEAQFGDFANGAQV+FDQFISSGE KWLR +GLV LLPHGY+GQGPEHSSARLE
Sbjct: 732 PRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGYEGQGPEHSSARLE 791
Query: 365 RYLQM-SDDNPYVIPDMEPT-----LRKQIQ 439
R+LQM ++DN V P LR+Q++
Sbjct: 792 RWLQMCAEDNMQVANVTTPANYFHILRRQMK 822
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,413,996,008
Number of Sequences: 518415
Number of Extensions: 65413996008
Number of Successful Extensions: 465124098
Number of sequences better than 0.0: 0
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