BLASTX 7.6.2
Query= UN16269 /QuerySize=1111
(1110 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54FM3|EI2BD_DICDI Translation initiation factor eIF-2B subun... 271 9e-072
sp|Q63186|EI2BD_RAT Translation initiation factor eIF-2B subunit... 265 7e-070
sp|Q61749|EI2BD_MOUSE Translation initiation factor eIF-2B subun... 264 9e-070
sp|Q09924|EI2BD_SCHPO Probable translation initiation factor eIF... 263 2e-069
sp|Q9UI10|EI2BD_HUMAN Translation initiation factor eIF-2B subun... 262 3e-069
sp|P41111|EI2BD_RABIT Translation initiation factor eIF-2B subun... 262 3e-069
sp|Q3T058|EI2BD_BOVIN Translation initiation factor eIF-2B subun... 258 5e-068
sp|P12754|EI2BD_YEAST Translation initiation factor eIF-2B subun... 188 8e-047
sp|Q54I81|EI2BA_DICDI Translation initiation factor eIF-2B subun... 103 3e-021
sp|O57947|EI2B2_PYRHO Putative translation initiation factor eIF... 95 7e-019
sp|Q9V281|EI2B2_PYRAB Putative translation initiation factor eIF... 93 3e-018
sp|Q57586|EI2B2_METJA Putative translation initiation factor eIF... 91 2e-017
sp|Q8U4G6|EI2B2_PYRFU Putative translation initiation factor eIF... 90 2e-017
sp|Q54EY2|EI2BB_DICDI Translation initiation factor eIF-2B subun... 86 3e-016
sp|Q9USP0|EI2BA_SCHPO Translation initiation factor eIF-2B subun... 70 3e-011
sp|Q8U3J1|EI2BL_PYRFU Putative translation initiation factor eIF... 67 2e-010
sp|Q9UYB6|EI2BL_PYRAB Putative translation initiation factor eIF... 66 3e-010
sp|O31662|MTNA_BACSU Methylthioribose-1-phosphate isomerase OS=B... 52 9e-006
>sp|Q54FM3|EI2BD_DICDI Translation initiation factor eIF-2B subunit delta
OS=Dictyostelium discoideum GN=eif2b4 PE=3 SV=1
Length = 619
Score = 271 bits (691), Expect = 9e-072
Identities = 141/295 (47%), Positives = 203/295 (68%), Gaps = 4/295 (1%)
Frame = +1
Query: 1 AFQEAINDYTTPPMKDLTMDLTGKINGYVSFLIECRPLSMSMGNAIRFLKNQLRKLPVDL 180
AF + DY P K + +L + + FL++CRP+S+SMGN+I ++K++L L ++
Sbjct: 322 AFIQIFKDYVAAPDKVYSRELDSLLKRNIQFLVDCRPISISMGNSINYVKHKL-SLTNNM 380
Query: 181 SEAEAKASLCSEIGRFIDEKIILADKVIVQHAVTKIRDGEVLLTYGFSCVVEMILLYAHE 360
S A+ L I FI E+I +AD IV+H +KI DG+V+LTY S VVE+I+ A +
Sbjct: 381 SHEGARDYLIKSINEFI-ERIQMADNAIVKHGCSKINDGDVILTYASSHVVELIIQQAIQ 439
Query: 361 IGRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYTHINAVSYIMGEVTRVFLGASSIFSN 540
+KFR+++VDSRP EG++LL RLV G+ TY ++AVSYIM EVT+VF+GA S+ SN
Sbjct: 440 DKKKFRLIIVDSRPKHEGRELLHRLVLHGVKITYIMLHAVSYIMKEVTKVFVGAYSVLSN 499
Query: 541 GTLYSKVGTACVAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELGDP-DAIANVPLRT 717
G L S+ GT+ VA +A ++VP IVCCE YKF ERV LDSIC N++G+P D + N+ +
Sbjct: 500 GNLISRSGTSLVASMAKFYNVPFIVCCETYKFTERVQLDSICFNQIGNPQDLVQNLGEKE 559
Query: 718 NTKH-AKTMDNNKNLQFLNLMYDSTPAEYISMIVTDYGMIPPTSIPVIVREYRRE 879
+K + ++ L+ LNLMYD TP E I M++T++GM+PPTSIPV++REYR+E
Sbjct: 560 GSKSLLENWESYSTLKLLNLMYDLTPIELIDMVITEFGMLPPTSIPVVLREYRKE 614
>sp|Q63186|EI2BD_RAT Translation initiation factor eIF-2B subunit delta
OS=Rattus norvegicus GN=Eif2b4 PE=2 SV=1
Length = 524
Score = 265 bits (675), Expect = 7e-070
Identities = 137/288 (47%), Positives = 192/288 (66%), Gaps = 2/288 (0%)
Frame = +1
Query: 1 AFQEAINDYTTPPMKDLTMDLTGKINGYVSFLIECRPLSMSMGNAIRFLKNQLRKLPVDL 180
A Q+ I DYTTPP ++L+ DL K+ Y+SFL +CRP+S SM NAI+F ++ +
Sbjct: 233 ALQQVIQDYTTPPNEELSRDLVNKLKPYISFLTQCRPMSASMCNAIKFFNKEVTGMSSSK 292
Query: 181 SEAEAKASLCSEIGRFIDEKIILADKVIVQHAVTKIRDGEVLLTYGFSCVVEMILLYAHE 360
E EAK+ L I R++ EKI+LA + I + A KI DG+V+L YG S +V IL A
Sbjct: 293 REEEAKSELKEAIDRYVQEKIVLASQAISRFASKKISDGDVILVYGCSSLVSRILQEAWV 352
Query: 361 IGRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYTHINAVSYIMGEVTRVFLGASSIFSN 540
GR+FRVVVVDSRP LEG+ +L LV G+ +Y I A SY++ EV++V LGA ++ +N
Sbjct: 353 EGRRFRVVVVDSRPRLEGRHMLHCLVRAGVPTSYLLIPAASYVLPEVSKVLLGAHALLAN 412
Query: 541 GTLYSKVGTACVAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELGDPDAIANVPLRTN 720
G++ S+VGTA +A+VA A +VPV+VCCE YKF ERV D+ SNEL DPD + R +
Sbjct: 413 GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQ--CKRGD 470
Query: 721 TKHAKTMDNNKNLQFLNLMYDSTPAEYISMIVTDYGMIPPTSIPVIVR 864
NN +L+ LNL+YD TP E + +++T+ GMIP +S+PV++R
Sbjct: 471 QVTLANWQNNSSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLR 518
>sp|Q61749|EI2BD_MOUSE Translation initiation factor eIF-2B subunit delta OS=Mus
musculus GN=Eif2b4 PE=2 SV=1
Length = 524
Score = 264 bits (674), Expect = 9e-070
Identities = 136/288 (47%), Positives = 194/288 (67%), Gaps = 2/288 (0%)
Frame = +1
Query: 1 AFQEAINDYTTPPMKDLTMDLTGKINGYVSFLIECRPLSMSMGNAIRFLKNQLRKLPVDL 180
A Q+ I DYTTPP ++L+ DL K+ Y+SFL +CRP+S SM NAI+FL ++ +
Sbjct: 233 ALQQVIQDYTTPPSEELSRDLVNKLKPYISFLTQCRPMSASMCNAIKFLTKEVTGMSSSK 292
Query: 181 SEAEAKASLCSEIGRFIDEKIILADKVIVQHAVTKIRDGEVLLTYGFSCVVEMILLYAHE 360
E EAK+ L + R++ EKI+LA + I + A TKI DG+V+L YG S +V IL A
Sbjct: 293 REEEAKSELKEALDRYVQEKIVLAAQAISRFASTKISDGDVILVYGCSSLVSRILQEARV 352
Query: 361 IGRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYTHINAVSYIMGEVTRVFLGASSIFSN 540
GR+FRVVVVDSRP LEG+ +L LV G+ +Y I A SY++ EV++V LGA ++ +N
Sbjct: 353 EGRRFRVVVVDSRPRLEGRHMLHSLVRAGVPTSYLLIPAASYVLPEVSKVLLGAHALLAN 412
Query: 541 GTLYSKVGTACVAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELGDPDAIANVPLRTN 720
G++ S+VGTA +A+VA A +VPV+VCCE YKF ERV D+ SNEL DPD + R +
Sbjct: 413 GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQ--CKRGD 470
Query: 721 TKHAKTMDNNKNLQFLNLMYDSTPAEYISMIVTDYGMIPPTSIPVIVR 864
++ +L+ LNL+YD TP E + +++T+ GMIP +S+PV++R
Sbjct: 471 QVALANWQSHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLR 518
>sp|Q09924|EI2BD_SCHPO Probable translation initiation factor eIF-2B subunit
delta OS=Schizosaccharomyces pombe GN=tif224 PE=1 SV=1
Length = 467
Score = 263 bits (671), Expect = 2e-069
Identities = 133/294 (45%), Positives = 197/294 (67%), Gaps = 3/294 (1%)
Frame = +1
Query: 4 FQEAINDYTTPPMKDLTMDLTGKINGYVSFLIECRPLSMSMGNAIRFLKNQLRKLPVDLS 183
F+ I DY TP L+ LT IN +++L+ RPLS+SMGNAIRFLK ++ L +DL+
Sbjct: 171 FKIVIQDYQTPYGTTLSRHLTTHINSQIAYLVSTRPLSISMGNAIRFLKLEISVLDIDLT 230
Query: 184 EAEAKASLCSEIGRFIDEKIILADKVIVQHAVTKIRDGEVLLTYGFSCVVEMILLYAHEI 363
+ E K L +I +I ++II+A +VIVQ A KI+DG+V+LTY S V +L++A +
Sbjct: 231 DDEGKELLLEKIDSYIRDRIIIAGQVIVQAATEKIQDGDVILTYLHSSTVNDVLIHAKNV 290
Query: 364 GRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYTHINAVSYIMGEVTRVFLGASSIFSNG 543
G+KFRVVVVDSRP EG+ L+ L G++CTY I+A+SYIM EVT++FLG ++ SNG
Sbjct: 291 GKKFRVVVVDSRPEFEGRVCLKLLTEHGIECTYVMISALSYIMQEVTKIFLGGHAMLSNG 350
Query: 544 TLYSKVGTACVAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELGDPDAIANVPLRTNT 723
LYS+ GT+ ++++ + +VPVI CCE+YKF ER+ LDS+ NEL D + N+ +
Sbjct: 351 ALYSRAGTSLISLLGHESNVPVIACCESYKFTERIQLDSLVYNELAPGDQLVNMGVDDFE 410
Query: 724 KHAKTMDN---NKNLQFLNLMYDSTPAEYISMIVTDYGMIPPTSIPVIVREYRR 876
+ + N KNL+ L+L YD TP I++ V + G++P TS+P I+ E+++
Sbjct: 411 EKPGVLANWKSVKNLKLLSLKYDVTPPRLITVCVCEMGLLPSTSVPAIINEFKQ 464
>sp|Q9UI10|EI2BD_HUMAN Translation initiation factor eIF-2B subunit delta
OS=Homo sapiens GN=EIF2B4 PE=1 SV=2
Length = 523
Score = 262 bits (669), Expect = 3e-069
Identities = 138/288 (47%), Positives = 193/288 (67%), Gaps = 2/288 (0%)
Frame = +1
Query: 1 AFQEAINDYTTPPMKDLTMDLTGKINGYVSFLIECRPLSMSMGNAIRFLKNQLRKLPVDL 180
A Q+ I DYTTPP ++L+ DL K+ Y+SFL +CRPLS SM NAI+FL ++ +
Sbjct: 232 ALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSK 291
Query: 181 SEAEAKASLCSEIGRFIDEKIILADKVIVQHAVTKIRDGEVLLTYGFSCVVEMILLYAHE 360
E EAK+ L + I R++ EKI+LA + I + A KI +G+V+L YG S +V IL A
Sbjct: 292 REEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWT 351
Query: 361 IGRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYTHINAVSYIMGEVTRVFLGASSIFSN 540
GR+FRVVVVDSRP LEG+ LR LV G+ +Y I A SY++ EV++V LGA ++ +N
Sbjct: 352 EGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLAN 411
Query: 541 GTLYSKVGTACVAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELGDPDAIANVPLRTN 720
G++ S+VGTA +A+VA A +VPV+VCCE YKF ERV D+ SNEL DPD + R
Sbjct: 412 GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQ--CKRGE 469
Query: 721 TKHAKTMDNNKNLQFLNLMYDSTPAEYISMIVTDYGMIPPTSIPVIVR 864
N+ +L+ LNL+YD TP E + +++T+ GMIP +S+PV++R
Sbjct: 470 HVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLR 517
>sp|P41111|EI2BD_RABIT Translation initiation factor eIF-2B subunit delta
OS=Oryctolagus cuniculus GN=EIF2B4 PE=2 SV=2
Length = 523
Score = 262 bits (669), Expect = 3e-069
Identities = 137/288 (47%), Positives = 194/288 (67%), Gaps = 2/288 (0%)
Frame = +1
Query: 1 AFQEAINDYTTPPMKDLTMDLTGKINGYVSFLIECRPLSMSMGNAIRFLKNQLRKLPVDL 180
A Q+ I DYTTPP ++L+ DL K+ Y+ FL +CRPLS SM NAI+FL ++ +
Sbjct: 232 ALQQVIQDYTTPPNEELSRDLVNKLKPYICFLTQCRPLSASMYNAIKFLNKEITGVSSTK 291
Query: 181 SEAEAKASLCSEIGRFIDEKIILADKVIVQHAVTKIRDGEVLLTYGFSCVVEMILLYAHE 360
E EAKA L + R++ EKI+LA + I++ A KI +G+V+L YG S +V IL A
Sbjct: 292 REEEAKAELQAAADRYVQEKIVLAAQAILRFASKKISNGDVILVYGCSSLVSRILQEAWS 351
Query: 361 IGRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYTHINAVSYIMGEVTRVFLGASSIFSN 540
GRKFRVVVVDSRP LEG+ +LR LV G+ +Y I A SY++ EV++V LGA ++ +N
Sbjct: 352 EGRKFRVVVVDSRPRLEGRHMLRFLVRAGVPASYLLIPAASYVLPEVSKVLLGAHALLAN 411
Query: 541 GTLYSKVGTACVAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELGDPDAIANVPLRTN 720
G++ S+VGTA +A+VA A +VPV+VCCE YKF ERV D+ SNEL DPD + R +
Sbjct: 412 GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCE--RGD 469
Query: 721 TKHAKTMDNNKNLQFLNLMYDSTPAEYISMIVTDYGMIPPTSIPVIVR 864
++ +L+ LNL+YD TP E + +++T+ GMIP +S+PV++R
Sbjct: 470 HVALANWQSHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLR 517
>sp|Q3T058|EI2BD_BOVIN Translation initiation factor eIF-2B subunit delta OS=Bos
taurus GN=EIF2B4 PE=2 SV=1
Length = 524
Score = 258 bits (659), Expect = 5e-068
Identities = 138/290 (47%), Positives = 192/290 (66%), Gaps = 6/290 (2%)
Frame = +1
Query: 1 AFQEAINDYTTPPMKDLTMDLTGKINGYVSFLIECRPLSMSMGNAIRFLKNQLRKLPVDL 180
A Q+ I DYTTPP ++L+ DL K+ Y SFL +CRPLS SM NAI+ L ++ +
Sbjct: 233 ALQQVIQDYTTPPSEELSRDLVNKLKPYFSFLTQCRPLSASMYNAIKLLNKEITGVSGSK 292
Query: 181 SEAEAKASLCSEIGRFIDEKIILADKVIVQHAVTKIRDGEVLLTYGFSCVVEMILLYAHE 360
E EAK+ L + I R+I EKI+LA + I + A KI +G+V+L YG S +V IL A
Sbjct: 293 REEEAKSELRAAIDRYIKEKIVLAAQAISRFAYKKISNGDVILVYGCSSLVSHILQEAWA 352
Query: 361 IGRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYTHINAVSYIMGEVTRVFLGASSIFSN 540
GR+FRVVVVDSRP LE + LR LV G+ +Y I A SY++ EV++V LGA ++ +N
Sbjct: 353 KGRQFRVVVVDSRPRLEAKHTLRSLVRAGVPASYLLIPAASYVLPEVSKVLLGAHALLAN 412
Query: 541 GTLYSKVGTACVAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELGDPDAIANVPLRTN 720
G++ S+VGTA +A+VA A +VPV+VCCE YKF ERV D+ SNEL DPD + L
Sbjct: 413 GSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDL----LCER 468
Query: 721 TKHA--KTMDNNKNLQFLNLMYDSTPAEYISMIVTDYGMIPPTSIPVIVR 864
+H N+ +L+ LNL+YD TP E + +++T+ GMIP +S+PV++R
Sbjct: 469 GEHVALANWQNHSSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLR 518
>sp|P12754|EI2BD_YEAST Translation initiation factor eIF-2B subunit delta
OS=Saccharomyces cerevisiae GN=GCD2 PE=1 SV=1
Length = 651
Score = 188 bits (476), Expect = 8e-047
Identities = 102/236 (43%), Positives = 150/236 (63%), Gaps = 2/236 (0%)
Frame = +1
Query: 4 FQEAINDYTTPPMKDLTMDLTGKINGYVSFLIECRPLSMSMGNAIRFLKNQLRKLPVDLS 183
FQ I DY TP L+ +LT ++ + L + RPLS++MGNAIR+LK ++ +
Sbjct: 300 FQIVIKDYQTPKGTTLSRNLTSYLSHQIDLLKKARPLSVTMGNAIRWLKQEISLIDPSTP 359
Query: 184 EAEAKASLCSEIGRFIDEKIILADKVIVQHAVTKIRDGEVLLTYGFSCVVEMILLY-AHE 360
+ AK LC +IG+F EKI LAD++I+ +A T+I + ++TYG S V+ +LL+ A
Sbjct: 360 DKAAKKDLCEKIGQFAKEKIELADQLIIDNASTQIEESTTIVTYGSSKVLTELLLHNAIS 419
Query: 361 IGRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYTHINAVSYIMG-EVTRVFLGASSIFS 537
+ + +V+VVDSRP EG+K+ L G++ Y I ++ I +V VFLGA SI S
Sbjct: 420 LKKNIKVIVVDSRPLFEGRKMAETLRNAGVNVMYALITSLDTIFNMDVDYVFLGAHSILS 479
Query: 538 NGTLYSKVGTACVAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELGDPDAIANV 705
NG LYS+ GTA +AM A ++PV+VCCE+ KF +RV LDS+ NEL DP+ + N+
Sbjct: 480 NGFLYSRAGTAMLAMSAKRRNIPVLVCCESLKFSQRVQLDSVTFNELADPNDLVNI 535
>sp|Q54I81|EI2BA_DICDI Translation initiation factor eIF-2B subunit alpha
OS=Dictyostelium discoideum GN=eif2b1 PE=3 SV=1
Length = 321
Score = 103 bits (256), Expect = 3e-021
Identities = 71/236 (30%), Positives = 120/236 (50%), Gaps = 3/236 (1%)
Frame = +1
Query: 142 FLKNQLRKLPVDLSEAEAKASLCSEIGRFIDEKIILADKVIVQHAVTKIRDGEVLLTYGF 321
F++ ++ +D + S E G + K ++ I Q A IRDG +L +GF
Sbjct: 80 FIRFVTKRTELDFPNFDTCKSNLVERGEQLSNKSSMSRTKISQLADKFIRDGVTILVHGF 139
Query: 322 SCVVEMILLYAHEIGRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYTHINAVSYIMGEV 501
S VV +LL+A G++F V+V +SRP+ G K RL A + VS I+ +V
Sbjct: 140 SRVVLGLLLHAAFQGKRFSVIVTESRPDSSGYKTAARLQAANIPVKLIMDGGVSRIIDKV 199
Query: 502 TRVFLGASSIFSNGTLYSKVGTACVAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELG 681
V +GA +I NG + +K+GT +++VA AF P V E++KF L+ L
Sbjct: 200 DYVLVGAEAIVENGGIVNKIGTYQISIVAKAFKKPFYVAAESFKFTRSYPLNQSDIENLK 259
Query: 682 DPDAIANVPLRTNTKHAKTMDNNKNLQFLNLMYDSTPAEYISMIVTDYGMIPPTSI 849
+ D I+ P + + + +N + L + D TP YI+++ T+ G++ P+++
Sbjct: 260 N-DHISE-PFKA-CRSCSSCENPEQLTIDSPTLDYTPPSYITLLFTELGVLTPSAV 312
>sp|O57947|EI2B2_PYRHO Putative translation initiation factor eIF-2B subunit 2
OS=Pyrococcus horikoshii GN=PH0208 PE=3 SV=1
Length = 324
Score = 95 bits (235), Expect = 7e-019
Identities = 60/216 (27%), Positives = 114/216 (52%), Gaps = 7/216 (3%)
Frame = +1
Query: 94 LIECRPLSMSMGNAIRFLKNQLRKLPVDLSEAEA-KASLCSEIGRFI--DEKIILADKVI 264
L RP ++S+ NA+R++ ++++ + ++ E + + + FI EK I + I
Sbjct: 61 LYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAI---ERI 117
Query: 265 VQHAVTKIRDGEVLLTYGFSCVVEMILLYAHEIGRKFRVVVVDSRPNLEGQKLLRRLVAR 444
+ +I DG++++T+ S ++ A E G+ +V+V ++RP +G+ + L +
Sbjct: 118 GEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASY 177
Query: 445 GLDCTYTHINAVSYIMGEVTRVFLGASSIFSNGTLYSKVGTACVAMVANAFSVPVIVCCE 624
G+ Y +A + M +V +GA SI +NG + +K+GT+ +A+ A V V++ E
Sbjct: 178 GIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAE 237
Query: 625 AYKFHERVLLDSICSNELGDP-DAIANVPLRTNTKH 729
YKFH +L + E+ DP + I LRT K+
Sbjct: 238 TYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKN 273
>sp|Q9V281|EI2B2_PYRAB Putative translation initiation factor eIF-2B subunit 2
OS=Pyrococcus abyssi GN=aIF-2BII PE=3 SV=1
Length = 324
Score = 93 bits (229), Expect = 3e-018
Identities = 60/228 (26%), Positives = 118/228 (51%), Gaps = 7/228 (3%)
Frame = +1
Query: 58 DLTGKINGYVSFLIECRPLSMSMGNAIRFLKNQLRKLPVDLSEAEA-KASLCSEIGRFI- 231
+L ++ L + RP ++S+ NA+R++ ++ + ++ E + ++ + FI
Sbjct: 49 ELWTELKEAAKILYKTRPTAVSLPNALRYVMHRAKIAYSSGADLETLRFTVINSAKEFIH 108
Query: 232 -DEKIILADKVIVQHAVTKIRDGEVLLTYGFSCVVEMILLYAHEIGRKFRVVVVDSRPNL 408
EK I + I + +I DG+V++T+ S ++ A + G+ +V+V ++RP
Sbjct: 109 NSEKAI---ERIGEIGAKRIEDGDVIMTHCHSKAAISVMKTAFDQGKDIKVIVTETRPRW 165
Query: 409 EGQKLLRRLVARGLDCTYTHINAVSYIMGEVTRVFLGASSIFSNGTLYSKVGTACVAMVA 588
+G+ + L + G+ Y +A + M +V +GA SI +NG + +K+GT+ +A+ A
Sbjct: 166 QGKITAKELASYGIPVIYVVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTA 225
Query: 589 NAFSVPVIVCCEAYKFHERVLLDSICSNELGDP-DAIANVPLRTNTKH 729
V V++ E YKFH +L + E+ DP + I L+T K+
Sbjct: 226 KEHRVWVMIAAETYKFHPETMLGQLVEIEMRDPTEVIPEEELKTWPKN 273
>sp|Q57586|EI2B2_METJA Putative translation initiation factor eIF-2B subunit 2
OS=Methanocaldococcus jannaschii GN=MJ0122 PE=3 SV=1
Length = 308
Score = 91 bits (223), Expect = 2e-017
Identities = 52/185 (28%), Positives = 96/185 (51%), Gaps = 1/185 (0%)
Frame = +1
Query: 145 LKNQLRKLPVDLSEAEAKASLCSEIGRFIDEKIILADKVIVQHAVTKIRDGEVLLTYGFS 324
L N ++ + L+E K + FI+ + A + I + +I+DG+ +LT+ S
Sbjct: 73 LPNVVKYVLKGLNEENPKERVIERADEFINSS-LKAIENIGKFGANRIKDGDTILTHCNS 131
Query: 325 CVVEMILLYAHEIGRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYTHINAVSYIMGEVT 504
++ A++ G+ +V ++RP +G + L G+D T +AV Y + E+
Sbjct: 132 EAAISVIKTAYDEGKDIKVFCTETRPRNQGYLTAKTLYDYGIDVTLIVDSAVRYFIKEID 191
Query: 505 RVFLGASSIFSNGTLYSKVGTACVAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELGD 684
V +GA +I +NG L +K+GT+ +A++AN VP + E YKFH + ++ + E
Sbjct: 192 IVVVGADAITANGCLVNKIGTSQIALIANESRVPFLTAAETYKFHPKTIVGELIEIEERS 251
Query: 685 PDAIA 699
P+ +A
Sbjct: 252 PEEVA 256
>sp|Q8U4G6|EI2B2_PYRFU Putative translation initiation factor eIF-2B subunit 2
OS=Pyrococcus furiosus GN=PF0122 PE=3 SV=2
Length = 324
Score = 90 bits (222), Expect = 2e-017
Identities = 58/221 (26%), Positives = 114/221 (51%), Gaps = 7/221 (3%)
Frame = +1
Query: 94 LIECRPLSMSMGNAIRFLKNQLRKLPVDLSEAEA-KASLCSEIGRFI--DEKIILADKVI 264
L RP ++S+ NA+R++ + + ++ E+ + ++ + FI EK I + I
Sbjct: 61 LYNTRPTAVSLPNALRYVMYRGKIAYTSNADLESLRYTIINAAKEFIYNSEKAI---ERI 117
Query: 265 VQHAVTKIRDGEVLLTYGFSCVVEMILLYAHEIGRKFRVVVVDSRPNLEGQKLLRRLVAR 444
+ +I DG+V++T+ S ++ A + G+ +V+V ++RP +G+ + L +
Sbjct: 118 GEIGAKRIEDGDVIMTHCHSKAAISVMKTAFDQGKDIKVIVTETRPRWQGKITAKELASY 177
Query: 445 GLDCTYTHINAVSYIMGEVTRVFLGASSIFSNGTLYSKVGTACVAMVANAFSVPVIVCCE 624
G+ Y A + M +V +GA SI +NG + +++GTA +A+ A V V++ E
Sbjct: 178 GIPVIYIVDGAARHYMKMTDKVVMGADSITANGAVINQIGTALIALTAKEHRVWVMIAAE 237
Query: 625 AYKFHERVLLDSICSNELGDP-DAIANVPLRTNTKHAKTMD 744
YKFH +L + E+ DP + + L T K+ + ++
Sbjct: 238 TYKFHPETMLGQLVEIEMRDPTEVVPKEELETWPKNIEVLN 278
>sp|Q54EY2|EI2BB_DICDI Translation initiation factor eIF-2B subunit beta
OS=Dictyostelium discoideum GN=eif2b2 PE=3 SV=1
Length = 388
Score = 86 bits (212), Expect = 3e-016
Identities = 57/174 (32%), Positives = 85/174 (48%), Gaps = 4/174 (2%)
Frame = +1
Query: 172 VDLSEA--EAKASLCSEIGRFIDEKIILADKVIVQHAVTKIRDGEVLLTYGFSCVVEMIL 345
+D +E KA++ I IDE L + + + A+ I E ++T G S VE L
Sbjct: 155 IDFTETFPRLKAAIMDSINELIDELEGL-HRNVAEQAIEHIHSNETIMTLGCSRTVEEFL 213
Query: 346 LYAHEIGRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYTHINAVSYIMGEVTRVFLGAS 525
A R F+V+VV++ P+LEGQK L +D T +AV +M V +V +G
Sbjct: 214 KEAAR-KRSFKVIVVETAPSLEGQKTAISLSKASIDTTLITDSAVFAMMSRVNKVIIGTH 272
Query: 526 SIFSNGTLYSKVGTACVAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELGDP 687
++ +NG L + GT +A+ A SVP++VC YK D N G P
Sbjct: 273 AVMANGGLIATSGTHTLAVAAKYHSVPIVVCTGLYKLCPLYAYDQDTFNNFGSP 326
>sp|Q9USP0|EI2BA_SCHPO Translation initiation factor eIF-2B subunit alpha
OS=Schizosaccharomyces pombe GN=tif221 PE=2 SV=1
Length = 341
Score = 70 bits (169), Expect = 3e-011
Identities = 54/177 (30%), Positives = 84/177 (47%), Gaps = 6/177 (3%)
Frame = +1
Query: 112 LSMSMGNAI--RFLKNQLRKLPVDLSEAEAKASLCSEIGRFIDEKIILADKVIVQHAVTK 285
+S+S G I RF+ L D+ + E E G+ ++ + I
Sbjct: 77 ISLSAGCDIFQRFVTRSLH----DVGDFEQCKRHLVENGKLFIQRARACRQRIAHLGYPL 132
Query: 286 IRDGEVLLTYGFSCVVEMILLYAHEIGRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYT 465
IRDG V+LT+GFS V +LL A + +F+V V +SRP+ G + R L +
Sbjct: 133 IRDGSVILTHGFSRGVAAVLLAAAKRHVRFKVFVTESRPSGSGCLMTRTLKNACIPTCMV 192
Query: 466 HINAVSYIMGEVTRVFLGASSIFSNGTLYSKVGTACVAMVANAFSVPVIVCCEAYKF 636
+AVS+ M V V +GA + NG L +++GT +A+ A P E++KF
Sbjct: 193 LDSAVSFTMNRVDLVLVGAEGVVENGGLINQIGTFQLAVFAKHAHKPFYAVAESHKF 249
>sp|Q8U3J1|EI2BL_PYRFU Putative translation initiation factor eIF-2B subunit
2-like OS=Pyrococcus furiosus GN=PF0475 PE=3 SV=1
Length = 276
Score = 67 bits (162), Expect = 2e-010
Identities = 37/133 (27%), Positives = 65/133 (48%)
Frame = +1
Query: 250 ADKVIVQHAVTKIRDGEVLLTYGFSCVVEMILLYAHEIGRKFRVVVVDSRPNLEGQKLLR 429
A K I I G+V++T+ +S V IL A G++F+V++ +S P+ EG L +
Sbjct: 95 AKKEIASIGAQLIDSGDVIITHSYSSAVFEILKTAKRRGKQFKVILTESAPDYEGLYLAK 154
Query: 430 RLVARGLDCTYTHINAVSYIMGEVTRVFLGASSIFSNGTLYSKVGTACVAMVANAFSVPV 609
L ++ + + T +GA ++ +G + +K GT +A+ VP
Sbjct: 155 ALQDESIEVEIITDAQLGLFAKDATLAIVGADTVTKDGYVVNKAGTYLLAISCYESEVPF 214
Query: 610 IVCCEAYKFHERV 648
V E YKFH+++
Sbjct: 215 YVAAETYKFHQKI 227
>sp|Q9UYB6|EI2BL_PYRAB Putative translation initiation factor eIF-2B subunit
2-like OS=Pyrococcus abyssi GN=PYRAB15920 PE=3 SV=1
Length = 276
Score = 66 bits (160), Expect = 3e-010
Identities = 37/130 (28%), Positives = 64/130 (49%)
Frame = +1
Query: 286 IRDGEVLLTYGFSCVVEMILLYAHEIGRKFRVVVVDSRPNLEGQKLLRRLVARGLDCTYT 465
I DG+V++T+ FS V I A + + F+V++ +S P+ EG L L G++
Sbjct: 107 IDDGDVIITHSFSSSVLEIFKVAKDRRKSFKVIITESSPDYEGLHLANELENLGIEFEVI 166
Query: 466 HINAVSYIMGEVTRVFLGASSIFSNGTLYSKVGTACVAMVANAFSVPVIVCCEAYKFHER 645
+ + + T +GA + +G + +K GT +A+ + VP V E YKFH
Sbjct: 167 TDSQMGLFCRKATISMVGADMVTRDGFVVNKAGTYLLALACHESDVPFYVAAETYKFHPT 226
Query: 646 VLLDSICSNE 675
V + + +E
Sbjct: 227 VKSNEVVLHE 236
>sp|O31662|MTNA_BACSU Methylthioribose-1-phosphate isomerase OS=Bacillus
subtilis GN=mtnA PE=1 SV=1
Length = 353
Score = 52 bits (122), Expect = 9e-006
Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Frame = +1
Query: 379 VVVVDSRPNLEGQKLLR-RLVARGLDCTYTHINAVSYIMGE--VTRVFLGASSIFSNGTL 549
+ ++RP L+G +L L+ G+D T + ++ M E ++ V +GA I NG
Sbjct: 189 IYACETRPVLQGSRLTAWELMQGGIDVTLITDSMAAHTMKEKQISAVIVGADRIAKNGDT 248
Query: 550 YSKVGTACVAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELGDPDAIANV 705
+K+GT +A++ANAF +P V F +V + E DP+ + +
Sbjct: 249 ANKIGTYGLAILANAFDIPFFVAAPLSTFDTKVKCGADIPIEERDPEEVRQI 300
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,946,960,590
Number of Sequences: 518415
Number of Extensions: 65946960590
Number of Successful Extensions: 470808347
Number of sequences better than 0.0: 0
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