BLASTX 7.6.2
Query= UN16342 /QuerySize=1284
(1283 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 ... 447 1e-124
sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 ... 388 5e-107
sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 ... 371 1e-101
sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 ... 238 8e-062
sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 ... 236 3e-061
sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 ... 235 9e-061
sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 ... 234 1e-060
sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 ... 233 3e-060
sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation ... 216 3e-055
sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 ... 215 7e-055
sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2... 212 6e-054
sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 ... 203 2e-051
sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 ... 178 1e-043
sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 ... 173 3e-042
sp|C5A2A8|IF2B_THEGJ Translation initiation factor 2 subunit bet... 102 7e-021
sp|O58312|IF2B_PYRHO Translation initiation factor 2 subunit bet... 99 6e-020
sp|Q9UYR6|IF2B_PYRAB Translation initiation factor 2 subunit bet... 98 1e-019
sp|A2SSW2|IF2B_METLZ Translation initiation factor 2 subunit bet... 98 1e-019
sp|Q8U3I5|IF2B_PYRFU Translation initiation factor 2 subunit bet... 97 3e-019
>sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 subunit beta
OS=Arabidopsis thaliana GN=EMB1401 PE=2 SV=3
Length = 268
Score = 447 bits (1148), Expect = 1e-124
Identities = 225/269 (83%), Positives = 240/269 (89%), Gaps = 5/269 (1%)
Frame = +2
Query: 158 EIKEVKDEQD-LAPFDPTKKKKKTKVVIQDPIEDCTESSQPEKSDSLPANDGLESSFAGL 334
EI E+++EQ+ LAPFDP+KKKKK KVVIQ+P+ED ESSQ EKSDSLP NDGLESSF G+
Sbjct: 4 EINEIREEQEQLAPFDPSKKKKKKKVVIQEPVEDLAESSQTEKSDSLPVNDGLESSFTGM 63
Query: 335 KKKKKKPVEISSSLNGESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGSDRDYICD 514
KKKKKKP E SS LN ES+D EDLDE AND++E EGI L QQRYPWEGS+RDYI D
Sbjct: 64 KKKKKKPTE-SSLLNNESVDAGEDLDEIANDEQEGEEGIVL---QQRYPWEGSERDYIYD 119
Query: 515 ELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMN 694
ELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVM
Sbjct: 120 ELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMQ 179
Query: 695 FLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRFF 874
+LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRY+T+YVICLGCKSPDTILSKENR F
Sbjct: 180 YLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYITDYVICLGCKSPDTILSKENRLF 239
Query: 875 FFRCEKCGSGRSVAQIKAGFVARVGRRKT 961
F RCEKCGS RSVA IK GFVARV RRKT
Sbjct: 240 FLRCEKCGSQRSVAPIKTGFVARVSRRKT 268
Score = 440 bits (1130), Expect = 1e-122
Identities = 222/267 (83%), Positives = 237/267 (88%), Gaps = 6/267 (2%)
Frame = +2
Query: 146 DENNEIKEVKDEQDLAPFDPTKKKKKTKVVIQDPIEDCTESSQPEKSDSLPANDGLESSF 325
DE NEI+E +++ LAPFDP+KKKKK KVVIQ+P+ED ESSQ EKSDSLP NDGLESSF
Sbjct: 3 DEINEIRE--EQEQLAPFDPSKKKKKKKVVIQEPVEDLAESSQTEKSDSLPVNDGLESSF 60
Query: 326 AGLKKKKKKPVEISSSLNGESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGSDRDY 505
G+KKKKKKP E SS LN ES+D EDLDE AND++E EGI L QQRYPWEGS+RDY
Sbjct: 61 TGMKKKKKKPTE-SSLLNNESVDAGEDLDEIANDEQEGEEGIVL---QQRYPWEGSERDY 116
Query: 506 ICDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDH 685
I DELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDH
Sbjct: 117 IYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDH 176
Query: 686 VMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKEN 865
VM +LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRY+T+YVICLGCKSPDTILSKEN
Sbjct: 177 VMQYLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYITDYVICLGCKSPDTILSKEN 236
Query: 866 RFFFFRCEKCGSGRSVAQIKAGFVARV 946
R FF RCEKCGS RSVA IK GFVARV
Sbjct: 237 RLFFLRCEKCGSQRSVAPIKTGFVARV 263
>sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 subunit beta
OS=Malus domestica PE=2 SV=2
Length = 271
Score = 388 bits (996), Expect = 5e-107
Identities = 203/265 (76%), Positives = 222/265 (83%), Gaps = 7/265 (2%)
Frame = +2
Query: 167 EVKDE--QDLAPFDPTKKKKKTKVVIQDPIEDCTESSQPEKSDSLPANDGLESSFAGLKK 340
EVKDE D+APFDPTKKKKK +VVIQD +D + EK+++ A++G ES+FAGLKK
Sbjct: 8 EVKDEVVADIAPFDPTKKKKKKEVVIQDTTDD-SVGKLAEKAEACTASEGQESTFAGLKK 66
Query: 341 KKKKPVEISSSLNGESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGSDRDYICDEL 520
KKKKP+E +S LN ES D EDL+E +DEE EGI L+ YPWEGSDRDY +EL
Sbjct: 67 KKKKPIE-TSILNEESGDAVEDLNERTGEDEE-GEGIVLETPS--YPWEGSDRDYTYEEL 122
Query: 521 LGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFL 700
L RVF ILRENNP+LAGDRRRTVMRPPQVLREGTKK VFVNFMDLCKTMHRQPDHVM FL
Sbjct: 123 LDRVFTILRENNPDLAGDRRRTVMRPPQVLREGTKKAVFVNFMDLCKTMHRQPDHVMAFL 182
Query: 701 LAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRFFFF 880
LAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYV EYVICLGC+SPDTILSKENR FF
Sbjct: 183 LAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVNEYVICLGCQSPDTILSKENRLFFL 242
Query: 881 RCEKCGSGRSVAQIKAGFVARVGRR 955
RCEKCGSGRSVA KAGF+ARVGRR
Sbjct: 243 RCEKCGSGRSVAPNKAGFMARVGRR 267
>sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 subunit beta
OS=Triticum aestivum PE=1 SV=1
Length = 270
Score = 371 bits (950), Expect = 1e-101
Identities = 190/267 (71%), Positives = 219/267 (82%), Gaps = 5/267 (1%)
Frame = +2
Query: 158 EIKEVKDEQDLAPFDPTKKKKKTKVVIQDPIEDCTESSQPEKSDSLPANDGLESSFAGLK 337
+++ ++ ++APFDPTKKKKK KVVIQDP ++ + + EK++ L + E+SF GLK
Sbjct: 6 QMERKEEATEIAPFDPTKKKKKKKVVIQDPADEVDKLA--EKTEGLSVTESGEASFVGLK 63
Query: 338 KKKKKPVEISSSLNGESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGSDRDYICDE 517
KKKKK VE+ SL E+ D + LD+ +DE+ EGI L Q YPWEG+DRDY DE
Sbjct: 64 KKKKKLVELDPSL-VEAGDGEDTLDDQVGEDEQ-GEGIVLGGATQ-YPWEGTDRDYKYDE 120
Query: 518 LLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNF 697
LLGRVFNILRENNP+LAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQP+HVM F
Sbjct: 121 LLGRVFNILRENNPDLAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPEHVMMF 180
Query: 698 LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRFFF 877
LLAE+GTSGSLDGQQRLV+KGRFAPKNFE ILRRY+ EYVIC GCKSPDTILSKENR FF
Sbjct: 181 LLAEMGTSGSLDGQQRLVIKGRFAPKNFEAILRRYINEYVICHGCKSPDTILSKENRLFF 240
Query: 878 FRCEKCGSGRSVAQIKAGFVARVGRRK 958
RCE+CGS RSVA IKAGFVA+VGRRK
Sbjct: 241 LRCEQCGSSRSVAPIKAGFVAQVGRRK 267
>sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 subunit 2
OS=Mus musculus GN=Eif2s2 PE=1 SV=1
Length = 331
Score = 238 bits (606), Expect = 8e-062
Identities = 134/275 (48%), Positives = 176/275 (64%), Gaps = 14/275 (5%)
Frame = +2
Query: 146 DENNEIKEVKDE-QDLAPFDPTKKKKKTKVVIQ-DPIEDCTESSQPEKSDSLPA--NDGL 313
+E++ K+ D+ DL F+ KKKKKTK + D E+ + + E PA D L
Sbjct: 58 EEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEAIKDVKIESDAQEPAEPEDDL 117
Query: 314 ESSFAGLKKKKKKPVEISSSLNGESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGS 493
+ G KKKKKK V+ E L+ E L++ +D + +GI Q W GS
Sbjct: 118 D-IMLGNKKKKKKNVKFPE--EDEILEKDEALED---EDSKKDDGISFSSQT---AWAGS 168
Query: 494 DRDYICDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMH 670
+RDY +ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +H
Sbjct: 169 ERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLH 228
Query: 671 RQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTI 850
RQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTI
Sbjct: 229 RQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTI 288
Query: 851 LSKENRFFFFRCEKCGSGRSVAQIKAGFVARVGRR 955
L K+ R +F +CE C S SVA IK GF A G+R
Sbjct: 289 LQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 323
>sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 subunit 2
OS=Oryctolagus cuniculus GN=EIF2S2 PE=1 SV=1
Length = 333
Score = 236 bits (601), Expect = 3e-061
Identities = 134/275 (48%), Positives = 176/275 (64%), Gaps = 12/275 (4%)
Frame = +2
Query: 146 DENNEIKEVKDE-QDLAPFDPTKKKKKTKVVIQ-DPIEDCTESSQPEKSDSLPA--NDGL 313
+E++ K+ D+ DL F+ KKKKKTK + D E+ + + E PA D L
Sbjct: 58 EEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIENDVQEPAEPEDDL 117
Query: 314 ESSFAGLKKKKKKPVEISSSLNGESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGS 493
+ G KKKKKK V+ E L+ E L++ +D + +GI Q W GS
Sbjct: 118 D-IMLGNKKKKKKNVKFPD--EDEILEKDEALED---EDSKKDDGISFSNQTGP-AWAGS 170
Query: 494 DRDYICDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMH 670
+RDY +ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +H
Sbjct: 171 ERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLH 230
Query: 671 RQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTI 850
RQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTI
Sbjct: 231 RQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTI 290
Query: 851 LSKENRFFFFRCEKCGSGRSVAQIKAGFVARVGRR 955
L K+ R +F +CE C S SVA IK GF A G+R
Sbjct: 291 LQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 325
>sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 subunit 2
OS=Bos taurus GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 235 bits (597), Expect = 9e-061
Identities = 132/274 (48%), Positives = 174/274 (63%), Gaps = 10/274 (3%)
Frame = +2
Query: 146 DENNEIKEVKDE-QDLAPFDPTKKKKKTKVVIQ-DPIEDCTESSQPEKSDSLPANDGLE- 316
+E++ K+ D+ DL F+ KKKKK+K + D E+ + + E PA +
Sbjct: 58 EEDSRKKDASDDLDDLNFFNQKKKKKKSKKIFDIDEAEEGIKDLKIESDVQEPAEPEEDL 117
Query: 317 SSFAGLKKKKKKPVEISSSLNGESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGSD 496
G KKKKKK V+ E L+ E L++ +D + +GI Q W GS+
Sbjct: 118 DIMLGNKKKKKKVVKFPD--EDEVLEKDEALED---EDSKKDDGISFSNQTGP-AWAGSE 171
Query: 497 RDYICDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHR 673
RDY +ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +HR
Sbjct: 172 RDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHR 231
Query: 674 QPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTIL 853
QP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTIL
Sbjct: 232 QPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTIL 291
Query: 854 SKENRFFFFRCEKCGSGRSVAQIKAGFVARVGRR 955
K+ R +F +CE C S SVA IK GF A GRR
Sbjct: 292 QKDTRLYFLQCETCHSRCSVASIKTGFQAVTGRR 325
>sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 subunit 2
OS=Homo sapiens GN=EIF2S2 PE=1 SV=2
Length = 333
Score = 234 bits (596), Expect = 1e-060
Identities = 133/275 (48%), Positives = 174/275 (63%), Gaps = 12/275 (4%)
Frame = +2
Query: 146 DENNEIKEVKDE-QDLAPFDPTKKKKKTKVVIQ-DPIEDCTESSQPEKSDSLPA--NDGL 313
+E+ K+ D+ DL F+ KKKKKTK + D E+ + + E P D L
Sbjct: 58 EEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIESDVQEPTEPEDDL 117
Query: 314 ESSFAGLKKKKKKPVEISSSLNGESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGS 493
+ G KKKKKK V+ E L+ E L++ +D + +GI Q W GS
Sbjct: 118 D-IMLGNKKKKKKNVKFPD--EDEILEKDEALED---EDNKKDDGISFSNQTGP-AWAGS 170
Query: 494 DRDYICDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMH 670
+RDY +ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +H
Sbjct: 171 ERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLH 230
Query: 671 RQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTI 850
RQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTI
Sbjct: 231 RQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTI 290
Query: 851 LSKENRFFFFRCEKCGSGRSVAQIKAGFVARVGRR 955
L K+ R +F +CE C S SVA IK GF A G+R
Sbjct: 291 LQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 325
>sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 subunit 2
OS=Pongo abelii GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 233 bits (592), Expect = 3e-060
Identities = 132/275 (48%), Positives = 173/275 (62%), Gaps = 12/275 (4%)
Frame = +2
Query: 146 DENNEIKEVKDE-QDLAPFDPTKKKKKTKVVIQ-DPIEDCTESSQPEKSDSLPA--NDGL 313
+E+ K+ D+ DL F+ KKKKKTK + D E+ + + E P D L
Sbjct: 58 EEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIESDVQEPTEPEDDL 117
Query: 314 ESSFAGLKKKKKKPVEISSSLNGESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGS 493
+ G KKKKKK V+ E L+ E L++ +D + +GI Q W GS
Sbjct: 118 D-IMLGNKKKKKKNVKFPD--EDEILEKDEALED---EDNKKDDGISFSNQTGP-AWAGS 170
Query: 494 DRDYICDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMH 670
+RDY +ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +H
Sbjct: 171 ERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLH 230
Query: 671 RQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTI 850
RQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTI
Sbjct: 231 RQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTI 290
Query: 851 LSKENRFFFFRCEKCGSGRSVAQIKAGFVARVGRR 955
L K+ R +F +CE C S S A IK GF A G+R
Sbjct: 291 LQKDTRLYFLQCETCHSRCSAASIKTGFQAVTGKR 325
>sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation factor 2
subunit beta OS=Schizosaccharomyces pombe GN=tif212 PE=1 SV=2
Length = 321
Score = 216 bits (550), Expect = 3e-055
Identities = 116/239 (48%), Positives = 145/239 (60%), Gaps = 18/239 (7%)
Frame = +2
Query: 260 TESSQPEKSDSLPANDGLESSFAGLKKKKKKPVEISSSLNGESL------DTAEDLDEHA 421
+ +S E+++ + G E F+ +KKKKKK S + L D DL +
Sbjct: 92 SSASAEEQTEDITTESG-ELDFSSMKKKKKKKKSADLSAFEKELEASSTGDATSDLSKQT 150
Query: 422 NDDEEDAEGIDLQQQQQRYPWEGSDRDYICDELLGRVFNILRENNPELAGDRRRTVMRPP 601
D E E + W SDRDY ELL R F +LR NNPELAG++R+ + PP
Sbjct: 151 FDSENMGE----------HAWLKSDRDYYYPELLNRFFTLLRTNNPELAGEKRKYTIVPP 200
Query: 602 QVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNF 781
V REG KKT+F N D+ K MHR DHV+ FL AELGTSGS+DG RL++KGRF K
Sbjct: 201 SVHREG-KKTIFANISDISKRMHRSLDHVIQFLFAELGTSGSVDGSSRLIIKGRFQQKQI 259
Query: 782 EGILRRYVTEYVICLGCKSPDTILSKENRFFFFRCEKCGSGRSVAQIKAGFVARVGRRK 958
E +LRRY+ EYV C CKSPDTIL+KENR FF CE CGS RSV IK G+ A++G+RK
Sbjct: 260 ENVLRRYIVEYVTCKTCKSPDTILTKENRIFFMTCEACGSVRSVQAIKTGYQAQIGKRK 318
>sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 subunit 2
OS=Drosophila melanogaster GN=eIF-2beta PE=1 SV=1
Length = 312
Score = 215 bits (546), Expect = 7e-055
Identities = 105/187 (56%), Positives = 134/187 (71%), Gaps = 2/187 (1%)
Frame = +2
Query: 401 EDLDEHANDDEEDAEGIDLQQQQQR-YPWEGSDRDYICDELLGRVFNILRENNPELAGDR 577
++LDE D +D + D + + W GSDRDY DELL RVF I+ + NP++A R
Sbjct: 118 KELDELFADQADDDKSEDKENDEDNSSTWFGSDRDYTYDELLKRVFEIILDKNPDMAAGR 177
Query: 578 R-RTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVV 754
+ + VMRPPQVLR GTKKT F NFMD+ KT+HR P H+++FLLAELGTSGS+DG Q+L++
Sbjct: 178 KPKFVMRPPQVLRVGTKKTSFANFMDIAKTLHRLPKHLLDFLLAELGTSGSMDGNQQLII 237
Query: 755 KGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRFFFFRCEKCGSGRSVAQIKAGF 934
KGRF PK E +LRRY+ EYV C C+SP+TIL K+ R FF +CE CGS SVA IK+GF
Sbjct: 238 KGRFQPKQIENVLRRYIKEYVTCHTCRSPETILQKDTRLFFLQCESCGSRCSVASIKSGF 297
Query: 935 VARVGRR 955
A G+R
Sbjct: 298 QAVTGKR 304
>sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2 subunit 2-like
protein OS=Homo sapiens PE=1 SV=1
Length = 327
Score = 212 bits (538), Expect = 6e-054
Identities = 103/184 (55%), Positives = 135/184 (73%), Gaps = 2/184 (1%)
Frame = +2
Query: 410 DEHANDDEEDAEGIDLQQQQQRYP-WEGSDRDYICDELLGRVFNILRENNPEL-AGDRRR 583
++ A +DE++ + + Q P W GS+RDY +ELL RVFNI+RE NP++ AG++R+
Sbjct: 136 EDEALEDEDNKKDDGISFSNQTGPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRK 195
Query: 584 TVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGR 763
VM+PPQV+R GTKKT FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +LV+KGR
Sbjct: 196 FVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGR 255
Query: 764 FAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRFFFFRCEKCGSGRSVAQIKAGFVAR 943
F K E +LRRY+ EYV C C+SPDTIL K+ R +F +CE C S SVA IK GF A
Sbjct: 256 FQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDMRLYFLQCETCHSRCSVAIIKIGFQAV 315
Query: 944 VGRR 955
+G+R
Sbjct: 316 MGKR 319
>sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 subunit 2
OS=Dictyostelium discoideum GN=eif2s2 PE=3 SV=1
Length = 317
Score = 203 bits (516), Expect = 2e-051
Identities = 108/264 (40%), Positives = 162/264 (61%), Gaps = 10/264 (3%)
Frame = +2
Query: 161 IKEVKDEQDLAPFDPTKKKKKTKVVIQDPIEDCTESSQPEKSDSLPAND-GLESSFAGLK 337
+ + +DEQ+ K+KKK ++ + +E+ EK ++ A+D +E+ F G K
Sbjct: 44 MSQQEDEQEQEDEKKEKRKKKKAALLASTEGENSEAI--EKLENEGAHDEDIEAEFMGEK 101
Query: 338 KKKKKPVEIS-SSLNGESLDTAEDLDEHANDDEEDAEGIDLQQQ-----QQRYPWEGSDR 499
KKKKK + S ++ + T E + +D E E Q PW G+DR
Sbjct: 102 KKKKKSSKSSTTTTTSTTTTTTEPTETEPTEDGESKEKTITTSDGDTFVQGTIPWAGTDR 161
Query: 500 DYICDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQP 679
DY EL R++++L+ NNP+L D++RT M+PPQV+REGTKKT++ NF ++C T++R+
Sbjct: 162 DYKYSELTYRIYHLLQANNPDLISDQKRT-MKPPQVMREGTKKTIWANFAEICGTLNRKV 220
Query: 680 DHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSK 859
+HV N++ AELGT+GS+DG QRLV++GRF E ++R Y++EYV C CKSP+T+L +
Sbjct: 221 EHVYNYVFAELGTNGSIDGNQRLVIRGRFKTSQIEIVIRHYISEYVACRNCKSPNTVLER 280
Query: 860 ENRFFFFRCEKCGSGRSVAQIKAG 931
NR +F C C S RSVA IK G
Sbjct: 281 NNRLYFLCCNACNSKRSVAVIKKG 304
>sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 subunit beta
OS=Saccharomyces cerevisiae GN=SUI3 PE=1 SV=2
Length = 285
Score = 178 bits (449), Expect = 1e-043
Identities = 111/239 (46%), Positives = 141/239 (58%), Gaps = 23/239 (9%)
Frame = +2
Query: 269 SQPEKSDSLPANDGLES-SFAGLKKKKKKPVEISSSLNGESLDTAEDLDEHANDDEEDAE 445
S +++ P +D E+ LKKKKKK + S + L A LD N D E E
Sbjct: 59 SADAEAEKEPTDDIAEALGELSLKKKKKKTKDSSVDAFEKELAKA-GLD---NVDAESKE 114
Query: 446 GIDLQ----QQQQRYPWEGSDRDYICDELLGRVFNILRENNPELAGDRRRTVMR--PPQV 607
G QQ+ P+ ELL R FNILR NNPELAGDR R PP
Sbjct: 115 GTPSANSSIQQEVGLPY---------SELLSRFFNILRTNNPELAGDRSGPKFRIPPPVC 165
Query: 608 LREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEG 787
LR+G KKT+F N D+ + +HR P+H++ +L AELGTSGS+DGQ+RLV+KG+F K E
Sbjct: 166 LRDG-KKTIFSNIQDIAEKLHRSPEHLIQYLFAELGTSGSVDGQKRLVIKGKFQSKQMEN 224
Query: 788 ILRRYVTEYVICLGCKSPDTILSKE--NRFFFFRCEKCGSGRSVAQIKAGFVARVGRRK 958
+LRRY+ EYV C CKS +T L +E NR FF C+ CGS RSV+ IK GF A VG+R+
Sbjct: 225 VLRRYILEYVTCKTCKSINTELKREQSNRLFFMVCKSCGSTRSVSSIKTGFQATVGKRR 283
>sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 subunit 2
OS=Caenorhabditis elegans GN=K04G2.1 PE=3 SV=4
Length = 250
Score = 173 bits (437), Expect = 3e-042
Identities = 78/157 (49%), Positives = 113/157 (71%)
Frame = +2
Query: 485 EGSDRDYICDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKT 664
+G+ DY +E L V+ ++++ NP+ AGD+++ ++ P+V R G+KKT F NF+++C+
Sbjct: 81 KGAWPDYTYEEALTLVYQVMKDKNPDFAGDKKKFAIKLPEVARAGSKKTAFSNFLEICRL 140
Query: 665 MHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPD 844
M RQ HV+ FLLAELGT+GS+DG L+VKGR+ K FE +LR+Y+ EYV+C CKSP+
Sbjct: 141 MKRQDKHVLQFLLAELGTTGSIDGSNCLIVKGRWQQKQFESVLRKYIKEYVMCHTCKSPE 200
Query: 845 TILSKENRFFFFRCEKCGSGRSVAQIKAGFVARVGRR 955
T L+K+ R FF +C CGS SV IK+GF A VG+R
Sbjct: 201 TQLTKDTRLFFLQCTNCGSRCSVTAIKSGFKAVVGKR 237
>sp|C5A2A8|IF2B_THEGJ Translation initiation factor 2 subunit beta
OS=Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
GN=eIF2B PE=3 SV=1
Length = 142
Score = 102 bits (253), Expect = 7e-021
Identities = 47/125 (37%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Frame = +2
Query: 527 RVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLA 706
R+ + E PE + PP V+ +T+ NF+D+ + M+R P H++ F+L
Sbjct: 12 RLLDKAYEELPENVKSHKSRFEVPPAVVTIAGNRTIIENFVDIAEAMNRDPSHLLKFILR 71
Query: 707 ELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRFFFFRC 886
E+ T+G+L+G +R++++GRF P L++Y+ EYVIC C SPDT + K +RF+F +C
Sbjct: 72 EVATAGTLEG-RRVILQGRFTPYLIANKLKKYLKEYVICPVCGSPDTKIIKRDRFYFLKC 130
Query: 887 EKCGS 901
E CG+
Sbjct: 131 EACGA 135
>sp|O58312|IF2B_PYRHO Translation initiation factor 2 subunit beta OS=Pyrococcus
horikoshii GN=eif2b PE=3 SV=1
Length = 140
Score = 99 bits (245), Expect = 6e-020
Identities = 52/133 (39%), Positives = 82/133 (61%), Gaps = 5/133 (3%)
Frame = +2
Query: 503 YICDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 682
Y ++LL + + L EN + + R + V EG KT+ NF D+ + ++R P
Sbjct: 6 YDYEKLLEKAYEELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIAEALNRDPQ 61
Query: 683 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 862
H++ FLL E+ T+G+L+G +R+V++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-KRVVLQGRFTPYLIANKLKKYIKEYVICPVCGSPDTKIIKR 120
Query: 863 NRFFFFRCEKCGS 901
+RF+F +CE CG+
Sbjct: 121 DRFYFLKCEACGA 133
>sp|Q9UYR6|IF2B_PYRAB Translation initiation factor 2 subunit beta OS=Pyrococcus
abyssi GN=eif2b PE=3 SV=1
Length = 140
Score = 98 bits (243), Expect = 1e-019
Identities = 51/133 (38%), Positives = 82/133 (61%), Gaps = 5/133 (3%)
Frame = +2
Query: 503 YICDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 682
Y ++LL + + L EN + + R + V EG KT+ NF D+ + ++R P
Sbjct: 6 YDYEKLLEKAYEELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIAEALNRDPQ 61
Query: 683 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 862
H++ FLL E+ T+G+L+G +R+V++GRF P +++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-KRVVLQGRFTPYLIANKIKKYIKEYVICPVCGSPDTKIIKR 120
Query: 863 NRFFFFRCEKCGS 901
+RF+F +CE CG+
Sbjct: 121 DRFYFLKCEACGA 133
>sp|A2SSW2|IF2B_METLZ Translation initiation factor 2 subunit beta
OS=Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)
GN=eIF2B PE=3 SV=1
Length = 204
Score = 98 bits (242), Expect = 1e-019
Identities = 52/116 (44%), Positives = 68/116 (58%), Gaps = 2/116 (1%)
Frame = +2
Query: 581 RTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKG 760
R VM ++ EG K TV NF D+ +++R DH M F+L ELGT+G +DG R V G
Sbjct: 25 RFVMPKAKIYIEG-KTTVLENFSDIVDSLNRDKDHFMKFILGELGTAGKIDG-NRAVFNG 82
Query: 761 RFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRFFFFRCEKCGSGRSVAQIKA 928
+F F+ IL YV +YVIC C PDT L K++R CE CGS R + + KA
Sbjct: 83 KFEQAQFDAILETYVGDYVICSECGRPDTKLVKDDRVLMLLCEACGSKRPIRKRKA 138
>sp|Q8U3I5|IF2B_PYRFU Translation initiation factor 2 subunit beta OS=Pyrococcus
furiosus GN=eif2b PE=1 SV=1
Length = 140
Score = 97 bits (239), Expect = 3e-019
Identities = 52/133 (39%), Positives = 80/133 (60%), Gaps = 5/133 (3%)
Frame = +2
Query: 503 YICDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 682
Y ++LL + + L EN + + R + V EG KT+ NF D+ ++R P
Sbjct: 6 YDYEKLLEKAYQELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIADALNRDPQ 61
Query: 683 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 862
H++ FLL E+ T+G+L+G +R+V++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-RRVVLQGRFTPYLIANKLKKYIKEYVICPVCGSPDTKIIKR 120
Query: 863 NRFFFFRCEKCGS 901
+RF F +CE CG+
Sbjct: 121 DRFHFLKCEACGA 133
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,474,533,121
Number of Sequences: 518415
Number of Extensions: 66474533121
Number of Successful Extensions: 482350681
Number of sequences better than 0.0: 0
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