BLASTX 7.6.2
Query= UN16449 /QuerySize=1009
(1008 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P34106|ALA2_PANMI Alanine aminotransferase 2 OS=Panicum milia... 174 8e-043
sp|Q54MJ7|ALAM_DICDI Probable alanine aminotransferase, mitochon... 170 2e-041
sp|P52894|ALA2_HORVU Alanine aminotransferase 2 OS=Hordeum vulga... 166 4e-040
sp|Q6GM82|ALAT2_XENLA Alanine aminotransferase 2 OS=Xenopus laev... 153 3e-036
sp|Q8BGT5|ALAT2_MOUSE Alanine aminotransferase 2 OS=Mus musculus... 151 7e-036
sp|P24298|ALAT1_HUMAN Alanine aminotransferase 1 OS=Homo sapiens... 148 8e-035
sp|Q28DB5|ALAT2_XENTR Alanine aminotransferase 2 OS=Xenopus trop... 148 1e-034
sp|Q8TD30|ALAT2_HUMAN Alanine aminotransferase 2 OS=Homo sapiens... 147 1e-034
sp|A4IFH5|ALAT1_BOVIN Alanine aminotransferase 1 OS=Bos taurus G... 147 2e-034
sp|Q8QZR5|ALAT1_MOUSE Alanine aminotransferase 1 OS=Mus musculus... 146 3e-034
sp|Q6NYL5|ALAT2_DANRE Alanine aminotransferase 2-like OS=Danio r... 145 7e-034
sp|P25409|ALAT1_RAT Alanine aminotransferase 1 OS=Rattus norvegi... 142 4e-033
sp|P52893|ALAM_YEAST Probable alanine aminotransferase, mitochon... 127 1e-028
sp|P52892|ALAT_YEAST Probable alanine aminotransferase OS=Saccha... 124 2e-027
sp|Q10334|ALAT_SCHPO Putative alanine aminotransferase OS=Schizo... 117 1e-025
>sp|P34106|ALA2_PANMI Alanine aminotransferase 2 OS=Panicum miliaceum PE=1 SV=1
Length = 482
Score = 174 bits (441), Expect = 8e-043
Identities = 82/160 (51%), Positives = 112/160 (70%)
Frame = +2
Query: 371 EEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARIMTDGF 550
E+IYK+AS+ L N++ QI L+++PPK GD SY + E GIL+SL RRA+ + D F
Sbjct: 323 EQIYKIASVNLCSNITGQILASLVMNPPKVGDESYAAYKAEKDGILQSLARRAKALEDAF 382
Query: 551 NSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTVPGSGF 730
N+ + + CN EGAMY FPQI LP A++AAK A K PD FY L+LLE+TGI VPGSGF
Sbjct: 383 NNLEGISCNKAEGAMYLFPQIHLPKKAIEAAKAANKAPDAFYALRLLESTGIVVVPGSGF 442
Query: 731 GQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQYEN 850
GQ G + +R TILP E+++P ++ FK F++ FM +Y +
Sbjct: 443 GQVPGTWHIRCTILPQEDKIPAVITRFKAFHEAFMAEYRD 482
>sp|Q54MJ7|ALAM_DICDI Probable alanine aminotransferase, mitochondrial
OS=Dictyostelium discoideum GN=gpt PE=3 SV=1
Length = 534
Score = 170 bits (429), Expect = 2e-041
Identities = 80/163 (49%), Positives = 112/163 (68%)
Frame = +2
Query: 359 EEEEEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARIM 538
++ + EIYK+ASI L PNV Q+ + LMV PP G+ S+D + +E I ESL++RA ++
Sbjct: 372 QDVKAEIYKLASIGLCPNVIGQLVVDLMVRPPVAGEQSHDLYLKERDNIYESLKKRANLL 431
Query: 539 TDGFNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTVP 718
T+ N+ + V CN +EGAMY+FPQIRLP A++ A GK PD +YC++LLEATGI VP
Sbjct: 432 TNALNNLEGVTCNPSEGAMYAFPQIRLPAKAVEYANSIGKAPDAYYCIQLLEATGICVVP 491
Query: 719 GSGFGQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQYE 847
GSGFGQK+G + RTT LP+EE + + F+ FM +Y+
Sbjct: 492 GSGFGQKDGTWHFRTTFLPSEEAIEGVCKRIADFHQSFMNKYK 534
>sp|P52894|ALA2_HORVU Alanine aminotransferase 2 OS=Hordeum vulgare PE=2 SV=1
Length = 482
Score = 166 bits (418), Expect = 4e-040
Identities = 79/160 (49%), Positives = 107/160 (66%)
Frame = +2
Query: 371 EEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARIMTDGF 550
E+IYK+AS+ L N++ QI L+++PPK D SY + E GIL SL RRA+ + F
Sbjct: 323 EQIYKIASVNLCSNITGQILASLVMNPPKASDESYASYKAEKDGILASLARRAKALEHAF 382
Query: 551 NSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTVPGSGF 730
N + + CN EGAMY FPQI LP A++AAK A K PD FY L+LLE+TGI VPGSGF
Sbjct: 383 NKLEGITCNEAEGAMYVFPQICLPQKAIEAAKAANKAPDAFYALRLLESTGIVVVPGSGF 442
Query: 731 GQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQYEN 850
GQ G + R TILP E+++P ++ F F++ FM++Y +
Sbjct: 443 GQVPGTWHFRCTILPQEDKIPAVISRFTVFHEAFMSEYRD 482
>sp|Q6GM82|ALAT2_XENLA Alanine aminotransferase 2 OS=Xenopus laevis GN=gpt2 PE=2
SV=1
Length = 540
Score = 153 bits (384), Expect = 3e-036
Identities = 67/159 (42%), Positives = 106/159 (66%)
Frame = +2
Query: 368 EEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARIMTDG 547
++++ K+ S+ L P V Q+ + ++V+PPKPG+ SY QF E + +L +L +AR+ +
Sbjct: 381 KQQLTKLVSVRLCPPVPGQVLLDVIVNPPKPGEPSYKQFISEKQAVLNNLAEKARLTEEI 440
Query: 548 FNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTVPGSG 727
N + CN +GAMYSFP+I +P A++ A+ G+ PD+F+C+KLLE TGI VPGSG
Sbjct: 441 LNQAPGIRCNPVQGAMYSFPRIHIPEKAIKLAQAEGQAPDMFFCMKLLEETGICVVPGSG 500
Query: 728 FGQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQY 844
FGQ+EG R TILP +++ +++ K F+ +FM +Y
Sbjct: 501 FGQREGTHHFRMTILPPTDKLKSLLERLKDFHQKFMDEY 539
>sp|Q8BGT5|ALAT2_MOUSE Alanine aminotransferase 2 OS=Mus musculus GN=Gpt2 PE=2
SV=1
Length = 522
Score = 151 bits (381), Expect = 7e-036
Identities = 70/161 (43%), Positives = 110/161 (68%)
Frame = +2
Query: 362 EEEEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARIMT 541
E + ++ K+ S+ L P VS Q M ++V+PP+PG+ S++QF+RE + +L +L ++A++
Sbjct: 361 EIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPEPGEESFEQFSREKEFVLGNLAKKAKLTE 420
Query: 542 DGFNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTVPG 721
D FN + CN +GAMY+FP+I +P A++AA+ PD+FYC+KLLE TGI VPG
Sbjct: 421 DLFNQVPGIQCNPLQGAMYAFPRILIPAKAVEAAQSHKMAPDMFYCMKLLEETGICVVPG 480
Query: 722 SGFGQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQY 844
SGFGQ+EG + R TILP +++ ++ K F+ +F+ QY
Sbjct: 481 SGFGQREGTYHFRMTILPPVDKLKTVLHKVKDFHLKFLEQY 521
>sp|P24298|ALAT1_HUMAN Alanine aminotransferase 1 OS=Homo sapiens GN=GPT PE=1
SV=3
Length = 496
Score = 148 bits (372), Expect = 8e-035
Identities = 67/159 (42%), Positives = 104/159 (65%)
Frame = +2
Query: 368 EEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARIMTDG 547
++++ K+ S+ L P V Q + L+VSPP P D S+ QF E + +L L +A++
Sbjct: 337 QQQMLKLMSVRLCPPVPGQALLDLVVSPPAPTDPSFAQFQAEKQAVLAELAAKAKLTEQV 396
Query: 548 FNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTVPGSG 727
FN + CN +GAMYSFP+++LPP A++ A++ G PD+F+CL+LLE TGI VPGSG
Sbjct: 397 FNEAPGISCNPVQGAMYSFPRVQLPPRAVERAQELGLAPDMFFCLRLLEETGICVVPGSG 456
Query: 728 FGQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQY 844
FGQ+EG + R TILP E++ +++ +F+ +F +Y
Sbjct: 457 FGQREGTYHFRMTILPPLEKLRLLLEKLSRFHAKFTLEY 495
>sp|Q28DB5|ALAT2_XENTR Alanine aminotransferase 2 OS=Xenopus tropicalis GN=gpt2
PE=2 SV=1
Length = 524
Score = 148 bits (371), Expect = 1e-034
Identities = 66/159 (41%), Positives = 104/159 (65%)
Frame = +2
Query: 368 EEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARIMTDG 547
++++ K+ S+ L P V Q + ++V+PPKPG+ SY QF E + +L +L +AR+ +
Sbjct: 365 KQQLTKLVSVRLCPPVPGQALLDVIVNPPKPGEPSYKQFMAEKQAVLGNLAEKARLTEEI 424
Query: 548 FNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTVPGSG 727
N + CN +GAMYSFP+I +P A++ A+ G+ PD+F+C+KLLE TGI VPGSG
Sbjct: 425 LNQSPGIRCNPVQGAMYSFPRIHIPEKAIKLAQAEGQAPDMFFCMKLLEETGICVVPGSG 484
Query: 728 FGQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQY 844
FGQ+EG R TILP +++ +++ K F+ +F +Y
Sbjct: 485 FGQREGTHHFRMTILPPTDKLKSLLERLKDFHQKFTEEY 523
>sp|Q8TD30|ALAT2_HUMAN Alanine aminotransferase 2 OS=Homo sapiens GN=GPT2 PE=1
SV=1
Length = 523
Score = 147 bits (370), Expect = 1e-034
Identities = 69/161 (42%), Positives = 107/161 (66%)
Frame = +2
Query: 362 EEEEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARIMT 541
E + ++ K+ S+ L P VS Q M ++V+PP G+ S++QF+RE + +L +L ++A++
Sbjct: 362 EIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTE 421
Query: 542 DGFNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTVPG 721
D FN + CN +GAMY+FP+I +P A++AA+ PD+FYC+KLLE TGI VPG
Sbjct: 422 DLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPG 481
Query: 722 SGFGQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQY 844
SGFGQ+EG + R TILP E++ ++ K F+ F+ +Y
Sbjct: 482 SGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKY 522
>sp|A4IFH5|ALAT1_BOVIN Alanine aminotransferase 1 OS=Bos taurus GN=GPT PE=1
SV=1
Length = 496
Score = 147 bits (369), Expect = 2e-034
Identities = 65/159 (40%), Positives = 103/159 (64%)
Frame = +2
Query: 368 EEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARIMTDG 547
++++ K+ S+ L P Q+ + + VSPP P D S+ +F E + +L L +A++
Sbjct: 337 KQQMQKLRSVRLCPPTPGQVLLDVAVSPPAPSDPSFPRFQAERRAVLAELAAKAKLTEQV 396
Query: 548 FNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTVPGSG 727
FN + CN +GAMYSFP+++LPP A+Q A++ G PD+F+CL+LLE TGI VPGSG
Sbjct: 397 FNEAPGIRCNPVQGAMYSFPRVQLPPRAVQRAQELGLAPDMFFCLRLLEETGICVVPGSG 456
Query: 728 FGQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQY 844
FGQ+EG + R TILP E++ +++ +F+ +F +Y
Sbjct: 457 FGQREGTYHFRMTILPPMEKLRPLLEKLSQFHAKFTREY 495
>sp|Q8QZR5|ALAT1_MOUSE Alanine aminotransferase 1 OS=Mus musculus GN=Gpt PE=2
SV=3
Length = 496
Score = 146 bits (367), Expect = 3e-034
Identities = 70/163 (42%), Positives = 104/163 (63%)
Frame = +2
Query: 356 EEEEEEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARI 535
+ E ++++ K+ S+ L P V Q MG++VSPP P + S+ QF E + +L L +A++
Sbjct: 333 DAEVQKQMAKLMSVRLCPPVPGQALMGMVVSPPTPSEPSFKQFQAERQEVLAELAAKAKL 392
Query: 536 MTDGFNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTV 715
FN + CN +GAMYSFPQI+LP A+Q A+ G PD+F+CL LLE TGI V
Sbjct: 393 TEQVFNEAPGIRCNPVQGAMYSFPQIQLPLKAVQRAQDLGLAPDMFFCLCLLEETGICVV 452
Query: 716 PGSGFGQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQY 844
PGSGFGQ+EG + R TILP E++ +++ + F+ +F +Y
Sbjct: 453 PGSGFGQQEGTYHFRMTILPPMEKLRVLLEKLRHFHAKFTHEY 495
>sp|Q6NYL5|ALAT2_DANRE Alanine aminotransferase 2-like OS=Danio rerio GN=gpt2l
PE=2 SV=2
Length = 549
Score = 145 bits (364), Expect = 7e-034
Identities = 67/163 (41%), Positives = 102/163 (62%)
Frame = +2
Query: 356 EEEEEEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARI 535
+ + + ++ K+ S+ L P Q M L+V+PP+PG+ S+ F +E +L +L +A++
Sbjct: 386 DADVKAQLTKLVSVRLCPPAPGQALMDLVVNPPQPGEPSHQTFMQERTAVLSALAEKAKL 445
Query: 536 MTDGFNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTV 715
N+ + CN +GAMYSFP+I LP A+ AK G+ PD+FYC+KLLE TGI V
Sbjct: 446 TEQILNTVPGISCNPVQGAMYSFPRITLPERAISEAKAKGQAPDMFYCMKLLEETGICLV 505
Query: 716 PGSGFGQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQY 844
PGSGFGQ+EG + R TILP +++ +++ K F+ F QY
Sbjct: 506 PGSGFGQREGTYHFRMTILPPTDKLKLMLNKLKDFHQRFTQQY 548
>sp|P25409|ALAT1_RAT Alanine aminotransferase 1 OS=Rattus norvegicus GN=Gpt PE=1
SV=2
Length = 496
Score = 142 bits (357), Expect = 4e-033
Identities = 68/163 (41%), Positives = 103/163 (63%)
Frame = +2
Query: 356 EEEEEEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARI 535
+ E ++++ K+ S+ L P V Q M ++VSPP P + S+ QF E + +L L +A++
Sbjct: 333 DAEVQKQMGKLMSVRLCPPVPGQALMDMVVSPPTPSEPSFKQFQAERQEVLAELAAKAKL 392
Query: 536 MTDGFNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTV 715
FN + CN +GAMYSFPQ++LP A+Q A++ G PD+F+CL LLE TGI V
Sbjct: 393 TEQVFNEAPGIRCNPVQGAMYSFPQVQLPLKAVQRAQELGLAPDMFFCLCLLEETGICVV 452
Query: 716 PGSGFGQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQY 844
PGSGFGQ+EG + R TILP E++ +++ F+ +F +Y
Sbjct: 453 PGSGFGQQEGTYHFRMTILPPMEKLRLLLEKLSHFHAKFTHEY 495
>sp|P52893|ALAM_YEAST Probable alanine aminotransferase, mitochondrial
OS=Saccharomyces cerevisiae GN=ALT1 PE=1 SV=1
Length = 592
Score = 127 bits (318), Expect = 1e-028
Identities = 72/158 (45%), Positives = 96/158 (60%), Gaps = 1/158 (0%)
Frame = +2
Query: 362 EEEEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARIMT 541
E + I K+ASI+L P V+ Q + LMV PP G+ S++ E I E L RA +
Sbjct: 433 EMRQVILKLASISLCPVVTGQALVDLMVRPPVEGEESFESDQAERNSIHEKLITRAMTLY 492
Query: 542 DGFNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTVPG 721
+ FNS + + C +GAMY FP+I LP A+Q A+ PD FYC KLLE+TGI TVPG
Sbjct: 493 ETFNSLEGIECQKPQGAMYLFPKIDLPFKAVQEARHLELTPDEFYCKKLLESTGICTVPG 552
Query: 722 SGFGQKEGVFLLRTTILPAEEEMPEIMDSF-KKFNDEF 832
SGFGQ+ G + LRTT L E + +SF K+F D++
Sbjct: 553 SGFGQEPGTYHLRTTFLAPGLEWIKKWESFHKEFFDQY 590
>sp|P52892|ALAT_YEAST Probable alanine aminotransferase OS=Saccharomyces
cerevisiae GN=ALT2 PE=1 SV=1
Length = 507
Score = 124 bits (309), Expect = 2e-027
Identities = 63/161 (39%), Positives = 98/161 (60%), Gaps = 3/161 (1%)
Frame = +2
Query: 359 EEEEEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARIM 538
+E + ++K+ SI++ V+ Q + LMV PP+PGD SY+Q E I +R RA ++
Sbjct: 347 QEIRDALFKLMSISICSVVTGQAVVDLMVKPPQPGDESYEQDHDERLKIFHEMRTRANLL 406
Query: 539 TDGFNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTVP 718
+ F + + C +GAMY FP++ LP AL +++ G PD FYC LLE+TGI TVP
Sbjct: 407 YETFKELEGIECQKPQGAMYLFPRLVLPKKALCESERLGIEPDEFYCTSLLESTGICTVP 466
Query: 719 GSGFGQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFMTQ 841
GSGFGQ+ G + +RTT L + + +K+F+ +F ++
Sbjct: 467 GSGFGQRPGTYHVRTTFLAPGTKW---IQDWKEFHQDFFSK 504
>sp|Q10334|ALAT_SCHPO Putative alanine aminotransferase OS=Schizosaccharomyces
pombe GN=SPBC582.08 PE=2 SV=1
Length = 505
Score = 117 bits (292), Expect = 1e-025
Identities = 64/159 (40%), Positives = 94/159 (59%), Gaps = 3/159 (1%)
Frame = +2
Query: 359 EEEEEEIYKVASIALSPNVSAQIFMGLMVSPPKPGDISYDQFARESKGILESLRRRARIM 538
E +++I K+A+I + P V+ Q+ + ++V+PPKPGD SYD F +E I E+LR + R +
Sbjct: 346 EPAKDQILKLATIDICPPVAGQLLVDMLVNPPKPGDPSYDLFIKEVDEIHEALRLQCRQL 405
Query: 539 TDGFNSCKNVVCNFTEGAMYSFPQIRLPPGALQAAKQAGKVPDVFYCLKLLEATGISTVP 718
+G K V C GAMY P + LP + AK PD FY ++LL+ +GI VP
Sbjct: 406 YEGTKRMKRVSCLEPHGAMYLHPSVSLPEKLITTAKAQKIQPDEFYAIELLKRSGICVVP 465
Query: 719 GSGFGQKEGVFLLRTTILPAEEEMPEIMDSFKKFNDEFM 835
GSGFGQ EG + +R T L + E ++ F K ++E M
Sbjct: 466 GSGFGQPEGDYHIRITFL---AKGTEYIERFVKAHNEIM 501
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,474,533,121
Number of Sequences: 518415
Number of Extensions: 66474533121
Number of Successful Extensions: 482350681
Number of sequences better than 0.0: 0
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