BLASTX 7.6.2
Query= UN16455 /QuerySize=849
(848 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q91V92|ACLY_MOUSE ATP-citrate synthase OS=Mus musculus GN=Acl... 136 3e-031
sp|Q2TCH3|ACLY_SHEEP ATP-citrate synthase OS=Ovis aries GN=ACLY ... 136 3e-031
sp|Q32PF2|ACLY_BOVIN ATP-citrate synthase OS=Bos taurus GN=ACLY ... 135 4e-031
sp|P53396|ACLY_HUMAN ATP-citrate synthase OS=Homo sapiens GN=ACL... 135 5e-031
sp|P16638|ACLY_RAT ATP-citrate synthase OS=Rattus norvegicus GN=... 135 5e-031
sp|O13907|ACL2_SCHPO Probable ATP-citrate synthase subunit 2 OS=... 121 6e-027
sp|B4U901|SUCC_HYDS0 Succinyl-CoA ligase [ADP-forming] subunit b... 61 1e-008
>sp|Q91V92|ACLY_MOUSE ATP-citrate synthase OS=Mus musculus GN=Acly PE=1 SV=1
Length = 1091
Score = 136 bits (340), Expect = 3e-031
Identities = 85/244 (34%), Positives = 130/244 (53%), Gaps = 7/244 (2%)
Frame = +2
Query: 119 MARKKIREYDSKRLVKEHFKRLSGKELPIRSVQINQETDLNELVEKEPWLSSEKLVVKPD 298
M+ K I E K L+ ++ S + + ++ +TD L++ PWL S+ LVVKPD
Sbjct: 1 MSAKAISEQTGKELLYKYICTTSAIQNRFKYARVTPDTDWAHLLQDHPWLLSQSLVVKPD 60
Query: 299 MLFGKRGKSGLVALKLDFAEVATFVKERLGKEVEMSGCKGPITTFIVEPFVPHN--EEFY 472
L +RGK GLV + L V +++K RLG E + KG + F++EPFVPH+ EEFY
Sbjct: 61 QLIKRRGKLGLVGVNLSLDGVKSWLKPRLGHEATVGKAKGFLKNFLIEPFVPHSQAEEFY 120
Query: 473 LNIVSDRLGCSISFSECGGIDIEENWDKVKTISVPTGSSL-TPEICAPLVATLPLEIKGE 649
+ I + R G + F GG+D+ + K + + V L T +I L+ P + K
Sbjct: 121 VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNTEDIKRHLLVHAPEDKKEV 180
Query: 650 LEDFIQVIFTLFQDLDFTFLEMNPFALVDGKPYPLDM--RVSLMTPLLSKL*EWGDMN-P 820
L FI +F ++DL FT+LE+NP + Y LD+ +V + K+ +WGD+ P
Sbjct: 181 LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYILDLAAKVDATADYICKV-KWGDIEFP 239
Query: 821 HAFG 832
FG
Sbjct: 240 PPFG 243
>sp|Q2TCH3|ACLY_SHEEP ATP-citrate synthase OS=Ovis aries GN=ACLY PE=2 SV=1
Length = 1101
Score = 136 bits (340), Expect = 3e-031
Identities = 85/244 (34%), Positives = 129/244 (52%), Gaps = 7/244 (2%)
Frame = +2
Query: 119 MARKKIREYDSKRLVKEHFKRLSGKELPIRSVQINQETDLNELVEKEPWLSSEKLVVKPD 298
M+ K I E K L+ ++ S + + ++ +TD L++ PWL S+ LVVKPD
Sbjct: 1 MSAKAISEQTGKELLYKYICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQSLVVKPD 60
Query: 299 MLFGKRGKSGLVALKLDFAEVATFVKERLGKEVEMSGCKGPITTFIVEPFVPH--NEEFY 472
L +RGK GLV + L V +++K RLG+E + G + F++EPFVPH EEFY
Sbjct: 61 QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHTQEEEFY 120
Query: 473 LNIVSDRLGCSISFSECGGIDIEENWDKVKTISVPTGSSLTPE-ICAPLVATLPLEIKGE 649
+ I + R G + F GG+D+ + K + + V L PE I L+ P + K
Sbjct: 121 VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVAVDEKLNPEDIKKHLLVHAPEDKKEI 180
Query: 650 LEDFIQVIFTLFQDLDFTFLEMNPFALVDGKPYPLDM--RVSLMTPLLSKL*EWGDMN-P 820
L FI +F ++DL FT+LE+NP + Y LD+ +V + K+ +WGD+ P
Sbjct: 181 LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYILDLAAKVDATADYICKV-KWGDIEFP 239
Query: 821 HAFG 832
FG
Sbjct: 240 PPFG 243
>sp|Q32PF2|ACLY_BOVIN ATP-citrate synthase OS=Bos taurus GN=ACLY PE=2 SV=1
Length = 1091
Score = 135 bits (339), Expect = 4e-031
Identities = 84/244 (34%), Positives = 129/244 (52%), Gaps = 7/244 (2%)
Frame = +2
Query: 119 MARKKIREYDSKRLVKEHFKRLSGKELPIRSVQINQETDLNELVEKEPWLSSEKLVVKPD 298
M+ K I E K L+ ++ S + + ++ +TD L++ PWL S+ LVVKPD
Sbjct: 1 MSAKAISEQTGKELLYKYICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQSLVVKPD 60
Query: 299 MLFGKRGKSGLVALKLDFAEVATFVKERLGKEVEMSGCKGPITTFIVEPFVPH--NEEFY 472
L +RGK GL+ + L V +++K RLG+E + G + F++EPFVPH EEFY
Sbjct: 61 QLIKRRGKLGLIGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHTQEEEFY 120
Query: 473 LNIVSDRLGCSISFSECGGIDIEENWDKVKTISVPTGSSLTPE-ICAPLVATLPLEIKGE 649
+ I + R G + F GG+D+ + K + + V L PE I L+ P + K
Sbjct: 121 VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI 180
Query: 650 LEDFIQVIFTLFQDLDFTFLEMNPFALVDGKPYPLDM--RVSLMTPLLSKL*EWGDMN-P 820
L FI +F ++DL FT+LE+NP + Y LD+ +V + K+ +WGD+ P
Sbjct: 181 LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKV-KWGDIEFP 239
Query: 821 HAFG 832
FG
Sbjct: 240 PPFG 243
>sp|P53396|ACLY_HUMAN ATP-citrate synthase OS=Homo sapiens GN=ACLY PE=1 SV=3
Length = 1101
Score = 135 bits (338), Expect = 5e-031
Identities = 85/244 (34%), Positives = 129/244 (52%), Gaps = 7/244 (2%)
Frame = +2
Query: 119 MARKKIREYDSKRLVKEHFKRLSGKELPIRSVQINQETDLNELVEKEPWLSSEKLVVKPD 298
M+ K I E K L+ + S + + ++ +TD L++ PWL S+ LVVKPD
Sbjct: 1 MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD 60
Query: 299 MLFGKRGKSGLVALKLDFAEVATFVKERLGKEVEMSGCKGPITTFIVEPFVPHN--EEFY 472
L +RGK GLV + L V +++K RLG+E + G + F++EPFVPH+ EEFY
Sbjct: 61 QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY 120
Query: 473 LNIVSDRLGCSISFSECGGIDIEENWDKVKTISVPTGSSLTPE-ICAPLVATLPLEIKGE 649
+ I + R G + F GG+D+ + K + + V L PE I L+ P + K
Sbjct: 121 VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI 180
Query: 650 LEDFIQVIFTLFQDLDFTFLEMNPFALVDGKPYPLDM--RVSLMTPLLSKL*EWGDMN-P 820
L FI +F ++DL FT+LE+NP + Y LD+ +V + K+ +WGD+ P
Sbjct: 181 LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKV-KWGDIEFP 239
Query: 821 HAFG 832
FG
Sbjct: 240 PPFG 243
>sp|P16638|ACLY_RAT ATP-citrate synthase OS=Rattus norvegicus GN=Acly PE=1 SV=1
Length = 1100
Score = 135 bits (338), Expect = 5e-031
Identities = 85/244 (34%), Positives = 129/244 (52%), Gaps = 7/244 (2%)
Frame = +2
Query: 119 MARKKIREYDSKRLVKEHFKRLSGKELPIRSVQINQETDLNELVEKEPWLSSEKLVVKPD 298
M+ K I E K L+ ++ S + + ++ +TD L++ PWL S+ LVVKPD
Sbjct: 1 MSAKAISEQTGKELLYKYICTTSAIQNRFKYARVTPDTDWAHLLQDHPWLLSQSLVVKPD 60
Query: 299 MLFGKRGKSGLVALKLDFAEVATFVKERLGKEVEMSGCKGPITTFIVEPFVPHN--EEFY 472
L +RGK GLV + L V +++K RLG E + KG + F++EPFVPH+ EEFY
Sbjct: 61 QLIKRRGKLGLVGVNLSLDGVKSWLKPRLGHEATVGKAKGFLKNFLIEPFVPHSQAEEFY 120
Query: 473 LNIVSDRLGCSISFSECGGIDIEENWDKVKTISVPTGSSLTPE-ICAPLVATLPLEIKGE 649
+ I + R G + F GG+D+ + K + + V L E I L+ P + K
Sbjct: 121 VCIYATREGDYVLFHHEGGVDVGDVDTKAQKLLVGVDEKLNAEDIKRHLLVHAPEDKKEI 180
Query: 650 LEDFIQVIFTLFQDLDFTFLEMNPFALVDGKPYPLDM--RVSLMTPLLSKL*EWGDMN-P 820
L FI +F ++DL FT+LE+NP + Y LD+ +V + K+ +WGD+ P
Sbjct: 181 LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYILDLAAKVDATADYICKV-KWGDIEFP 239
Query: 821 HAFG 832
FG
Sbjct: 240 PPFG 243
>sp|O13907|ACL2_SCHPO Probable ATP-citrate synthase subunit 2
OS=Schizosaccharomyces pombe GN=SPAC22A12.16 PE=1 SV=1
Length = 492
Score = 121 bits (303), Expect = 6e-027
Identities = 69/173 (39%), Positives = 103/173 (59%), Gaps = 6/173 (3%)
Frame = +2
Query: 233 DLNELVEKE-PWLSSEKLVVKPDMLFGKRGKSGLVALKLDFAEVATFVKERLGKEVEMSG 409
D+ VE+E PW+ KLV KPD L +RGKSGL+ L + E +++ER GK ++
Sbjct: 66 DVFAKVEQEHPWVKETKLVAKPDQLIKRRGKSGLLKLNATWDEAKEWIRERAGKNQKVQH 125
Query: 410 CKGPITTFIVEPFVPH--NEEFYLNIVSDRLGCSISFSECGGIDIEENWDKVKTISVPTG 583
G +TTF+VEPFVPH N E+Y+NI S R G I F GG+D+ + K + + VP
Sbjct: 126 AVGYLTTFLVEPFVPHPPNTEYYININSVREGDWILFCNEGGVDVGDVDAKARKLLVPVR 185
Query: 584 SSLTPE---ICAPLVATLPLEIKGELEDFIQVIFTLFQDLDFTFLEMNPFALV 733
S P I + L++ +P+E L DFI +++++ D FT+LE+NP ++
Sbjct: 186 LSEFPSRATIASTLLSDIPVEQHESLVDFIIRLYSVYVDCQFTYLEINPLVVI 238
>sp|B4U901|SUCC_HYDS0 Succinyl-CoA ligase [ADP-forming] subunit beta
OS=Hydrogenobaculum sp. (strain Y04AAS1) GN=sucC PE=3 SV=1
Length = 382
Score = 61 bits (146), Expect = 1e-008
Identities = 52/195 (26%), Positives = 86/195 (44%), Gaps = 22/195 (11%)
Frame = +2
Query: 233 DLNELVEKEPWLSSEKLVVKPDMLFGKRGKSGLVALKLDFAEVATFVKERLGKEVEMSGC 412
++ E E L LVVK + G RGK+G V + E+ F + LGK ++ C
Sbjct: 27 NVKEAKEAAQALGGYPLVVKAQIHCGARGKAGGVKIVKSDEELEAFSEAILGKILKTVQC 86
Query: 413 KG--PITTFIVEPFVPHNEEFYLNIVSDRLGCSISF--SECGGIDIEENWDKVKTISVPT 580
++ ++E P +EFYL+I DR I S+ GG++IEE +S
Sbjct: 87 PNGKVVSRLLIEKATPIEKEFYLSITLDRSNSKILIMASKEGGMEIEE-------LSKEK 139
Query: 581 GSSLTPEICAPLVATLPLEIK----------GELEDFIQVIFTLFQDLDFTFLEMNPFAL 730
++ E P++ +P + + + ++ + DLD + LE+NP L
Sbjct: 140 PDAIIKEYVDPVLGIMPYQTRKLSFALGLNPSLFGKIVSKLYQAYMDLDASLLEINPLVL 199
Query: 731 V-DGKPYPLDMRVSL 772
DG LD +V +
Sbjct: 200 TKDGDIVLLDAKVEI 214
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,474,533,121
Number of Sequences: 518415
Number of Extensions: 66474533121
Number of Successful Extensions: 482350681
Number of sequences better than 0.0: 0
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