BLASTX 7.6.2
Query= UN16617 /QuerySize=736
(735 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q55BK0|UFD1_DICDI Ubiquitin fusion degradation protein 1 homo... 181 4e-045
sp|Q9VTF9|UFD1_DROME Ubiquitin fusion degradation protein 1 homo... 180 1e-044
sp|Q92890|UFD1_HUMAN Ubiquitin fusion degradation protein 1 homo... 179 1e-044
sp|Q9ES53|UFD1_RAT Ubiquitin fusion degradation protein 1 homolo... 179 1e-044
sp|P70362|UFD1_MOUSE Ubiquitin fusion degradation protein 1 homo... 179 3e-044
sp|O42915|UFD1_SCHPO Ubiquitin fusion degradation protein 1 OS=S... 163 1e-039
sp|P53044|UFD1_YEAST Ubiquitin fusion degradation protein 1 OS=S... 148 4e-035
sp|Q19584|UFD1_CAEEL Ubiquitin fusion degradation protein 1 homo... 133 1e-030
>sp|Q55BK0|UFD1_DICDI Ubiquitin fusion degradation protein 1 homolog
OS=Dictyostelium discoideum GN=ufd1 PE=3 SV=1
Length = 330
Score = 181 bits (459), Expect = 4e-045
Identities = 85/160 (53%), Positives = 120/160 (75%), Gaps = 3/160 (1%)
Frame = +3
Query: 114 GYHYPGT-TFEQSYRCYPASFI--DKPQIESGDKIIMPPSALDRLASLHIDYPMLFELRN 284
G+H+ G +EQ ++ +P SF+ +K +ESG KI++PPSAL+ L+ L+I YPMLFE+ N
Sbjct: 16 GHHHGGPGRYEQKFKAFPISFLPKEKHSLESGGKILLPPSALNALSRLNIQYPMLFEISN 75
Query: 285 AGIERVSHCGVLEFIAEEGMIYMPYWMMQNLLL*EGDIVRVRNVTLPKGTYVKLQPHTTD 464
+ SHCGVLEFIAEEG+ Y+P WMMQNL L EG+ + ++N TL KGT+VK+QP T++
Sbjct: 76 PISGKKSHCGVLEFIAEEGICYLPLWMMQNLQLKEGEFIDIKNATLAKGTFVKIQPRTSN 135
Query: 465 FLDISNLKAILETALRNYSCLTTGDSIMVPYNNKKYFIYI 584
F+DISN KA+LE +LR ++ LT D IM+ YNN KY++ +
Sbjct: 136 FIDISNPKAVLENSLRKFATLTKDDEIMIDYNNTKYYLKV 175
>sp|Q9VTF9|UFD1_DROME Ubiquitin fusion degradation protein 1 homolog
OS=Drosophila melanogaster GN=Ufd1-like PE=1 SV=1
Length = 316
Score = 180 bits (455), Expect = 1e-044
Identities = 86/161 (53%), Positives = 116/161 (72%), Gaps = 6/161 (3%)
Frame = +3
Query: 108 FDGYH--YP-GTTFEQSYRCYPASFI---DKPQIESGDKIIMPPSALDRLASLHIDYPML 269
F G++ +P G F +Y+C+ S + ++ +E G KIIMPPSALD L L+++YPML
Sbjct: 4 FSGFNMMFPEGRNFHANYKCFSVSMLPGNERTDVEKGGKIIMPPSALDTLTRLNVEYPML 63
Query: 270 FELRNAGIERVSHCGVLEFIAEEGMIYMPYWMMQNLLL*EGDIVRVRNVTLPKGTYVKLQ 449
F+L N R SH GVLEF+A+EG Y+P+WMM+NLLL EGDI+ + +V+LP T+ K Q
Sbjct: 64 FKLTNVKKSRSSHAGVLEFVADEGKCYLPHWMMENLLLGEGDILNIESVSLPVATFSKFQ 123
Query: 450 PHTTDFLDISNLKAILETALRNYSCLTTGDSIMVPYNNKKY 572
PH+TDFLDI+N KA+LE ALRN++CLT GD I + YN K Y
Sbjct: 124 PHSTDFLDITNPKAVLENALRNFACLTRGDVIAIKYNKKVY 164
>sp|Q92890|UFD1_HUMAN Ubiquitin fusion degradation protein 1 homolog OS=Homo
sapiens GN=UFD1L PE=1 SV=3
Length = 307
Score = 179 bits (454), Expect = 1e-044
Identities = 85/149 (57%), Positives = 110/149 (73%), Gaps = 4/149 (2%)
Frame = +3
Query: 138 FEQSYRCYPASFI----DKPQIESGDKIIMPPSALDRLASLHIDYPMLFELRNAGIERVS 305
F YRC+ S + D+ +E G KIIMPPSALD+L+ L+I YPMLF+L N +R++
Sbjct: 19 FSTQYRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLNITYPMLFKLTNKNSDRMT 78
Query: 306 HCGVLEFIAEEGMIYMPYWMMQNLLL*EGDIVRVRNVTLPKGTYVKLQPHTTDFLDISNL 485
HCGVLEF+A+EG+ Y+P+WMMQNLLL EG +V+V +V L TY K QP + DFLDI+N
Sbjct: 79 HCGVLEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVATYSKFQPQSPDFLDITNP 138
Query: 486 KAILETALRNYSCLTTGDSIMVPYNNKKY 572
KA+LE ALRN++CLTTGD I + YN K Y
Sbjct: 139 KAVLENALRNFACLTTGDVIAINYNEKIY 167
>sp|Q9ES53|UFD1_RAT Ubiquitin fusion degradation protein 1 homolog OS=Rattus
norvegicus GN=Ufd1l PE=1 SV=1
Length = 307
Score = 179 bits (454), Expect = 1e-044
Identities = 85/149 (57%), Positives = 110/149 (73%), Gaps = 4/149 (2%)
Frame = +3
Query: 138 FEQSYRCYPASFI----DKPQIESGDKIIMPPSALDRLASLHIDYPMLFELRNAGIERVS 305
F YRC+ S + D+ +E G KIIMPPSALD+L+ L+I YPMLF+L N +R++
Sbjct: 19 FSTQYRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLNITYPMLFKLTNKNSDRMT 78
Query: 306 HCGVLEFIAEEGMIYMPYWMMQNLLL*EGDIVRVRNVTLPKGTYVKLQPHTTDFLDISNL 485
HCGVLEF+A+EG+ Y+P+WMMQNLLL EG +V+V +V L TY K QP + DFLDI+N
Sbjct: 79 HCGVLEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVATYSKFQPQSPDFLDITNP 138
Query: 486 KAILETALRNYSCLTTGDSIMVPYNNKKY 572
KA+LE ALRN++CLTTGD I + YN K Y
Sbjct: 139 KAVLENALRNFACLTTGDVIAINYNEKIY 167
>sp|P70362|UFD1_MOUSE Ubiquitin fusion degradation protein 1 homolog OS=Mus
musculus GN=Ufd1l PE=1 SV=1
Length = 307
Score = 179 bits (452), Expect = 3e-044
Identities = 84/149 (56%), Positives = 110/149 (73%), Gaps = 4/149 (2%)
Frame = +3
Query: 138 FEQSYRCYPASFI----DKPQIESGDKIIMPPSALDRLASLHIDYPMLFELRNAGIERVS 305
F YRC+ S + D+ +E G KIIMPPSALD+L+ L+I YPMLF+L N +R++
Sbjct: 19 FSTQYRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLNITYPMLFKLTNKNSDRMT 78
Query: 306 HCGVLEFIAEEGMIYMPYWMMQNLLL*EGDIVRVRNVTLPKGTYVKLQPHTTDFLDISNL 485
HCGVLEF+A+EG+ Y+P+WMMQNLLL EG +V+V +V L TY K QP + DFLDI+N
Sbjct: 79 HCGVLEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVATYSKFQPQSPDFLDITNP 138
Query: 486 KAILETALRNYSCLTTGDSIMVPYNNKKY 572
KA+LE ALRN++C+TTGD I + YN K Y
Sbjct: 139 KAVLENALRNFACMTTGDVIAINYNEKIY 167
>sp|O42915|UFD1_SCHPO Ubiquitin fusion degradation protein 1
OS=Schizosaccharomyces pombe GN=ufd1 PE=2 SV=4
Length = 342
Score = 163 bits (412), Expect = 1e-039
Identities = 76/152 (50%), Positives = 108/152 (71%), Gaps = 3/152 (1%)
Frame = +3
Query: 138 FEQSYRCYPASFI---DKPQIESGDKIIMPPSALDRLASLHIDYPMLFELRNAGIERVSH 308
F+ YRCYP + I ++P + G K+I+PPSAL++L+ L++ YPMLF+ N E+ +H
Sbjct: 32 FDTRYRCYPVAMIPGEERPNVNYGGKVILPPSALEKLSRLNVSYPMLFDFENEAAEKKTH 91
Query: 309 CGVLEFIAEEGMIYMPYWMMQNLLL*EGDIVRVRNVTLPKGTYVKLQPHTTDFLDISNLK 488
GVLEFIAEEG +Y+PYWMM L L GD+VRV N + +G+YVKLQP + +FLDI++ +
Sbjct: 92 GGVLEFIAEEGRVYLPYWMMTTLSLEPGDLVRVINTDIAQGSYVKLQPQSVNFLDITDHR 151
Query: 489 AILETALRNYSCLTTGDSIMVPYNNKKYFIYI 584
A+LE ALRN+S LT D + YN++ Y I +
Sbjct: 152 AVLENALRNFSTLTKSDIFEILYNDQVYQIKV 183
>sp|P53044|UFD1_YEAST Ubiquitin fusion degradation protein 1 OS=Saccharomyces
cerevisiae GN=UFD1 PE=1 SV=1
Length = 361
Score = 148 bits (373), Expect = 4e-035
Identities = 75/154 (48%), Positives = 102/154 (66%), Gaps = 4/154 (2%)
Frame = +3
Query: 135 TFEQSYRCYPASF----IDKPQIESGDKIIMPPSALDRLASLHIDYPMLFELRNAGIERV 302
TFE+ +RCYP + I K G KI +PPSAL +L+ L+I YPMLF+L RV
Sbjct: 20 TFEEFFRCYPIAMMNDRIRKDDANFGGKIFLPPSALSKLSMLNIRYPMLFKLTANETGRV 79
Query: 303 SHCGVLEFIAEEGMIYMPYWMMQNLLL*EGDIVRVRNVTLPKGTYVKLQPHTTDFLDISN 482
+H GVLEFIAEEG +Y+P WMM+ L + G ++++ + +P G +VKL+P + DFLDIS+
Sbjct: 80 THGGVLEFIAEEGRVYLPQWMMETLGIQPGSLLQISSTDVPLGQFVKLEPQSVDFLDISD 139
Query: 483 LKAILETALRNYSCLTTGDSIMVPYNNKKYFIYI 584
KA+LE LRN+S LT D I + YN K + I I
Sbjct: 140 PKAVLENVLRNFSTLTVDDVIEISYNGKTFKIKI 173
>sp|Q19584|UFD1_CAEEL Ubiquitin fusion degradation protein 1 homolog
OS=Caenorhabditis elegans GN=ufd-1 PE=1 SV=1
Length = 342
Score = 133 bits (334), Expect = 1e-030
Identities = 66/146 (45%), Positives = 93/146 (63%), Gaps = 6/146 (4%)
Frame = +3
Query: 138 FEQSYRCYPASFIDK------PQIESGDKIIMPPSALDRLASLHIDYPMLFELRNAGIER 299
++Q++ Y F+ +I G KI++P SAL+ L +I PMLF+L N ++R
Sbjct: 21 YDQTFVVYGPVFLPNATQSKISEINYGGKILLPSSALNLLMQYNIPMPMLFKLTNMAVQR 80
Query: 300 VSHCGVLEFIAEEGMIYMPYWMMQNLLL*EGDIVRVRNVTLPKGTYVKLQPHTTDFLDIS 479
V+HCGVLEF A EG +P WMMQ L L +GD +R+ + TLPK T+ KL+P + +FL+I+
Sbjct: 81 VTHCGVLEFSAPEGQAILPLWMMQQLGLDDGDTIRIESATLPKATFAKLKPMSLEFLNIT 140
Query: 480 NLKAILETALRNYSCLTTGDSIMVPY 557
N KA+LE LR Y+CLT D I Y
Sbjct: 141 NPKAVLEVELRKYACLTKNDRIPTSY 166
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0
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