BLASTX 7.6.2
Query= UN16648 /QuerySize=639
(638 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O48651|ERG1_PANGI Squalene monooxygenase OS=Panax ginseng PE=... 210 1e-053
sp|O65404|ERG11_ARATH Squalene monooxygenase 1,1 OS=Arabidopsis ... 161 6e-039
sp|O65726|ERG12_BRANA Squalene monooxygenase 1,2 OS=Brassica nap... 156 2e-037
sp|O65402|ERG12_ARATH Squalene monooxygenase 1,2 OS=Arabidopsis ... 154 5e-037
sp|O65727|ERG11_BRANA Squalene monooxygenase 1,1 OS=Brassica nap... 149 2e-035
sp|O65403|ERG13_ARATH Squalene monooxygenase 2 OS=Arabidopsis th... 146 1e-034
sp|Q14534|ERG1_HUMAN Squalene monooxygenase OS=Homo sapiens GN=S... 124 8e-028
sp|P52019|ERG1_MOUSE Squalene monooxygenase OS=Mus musculus GN=S... 123 1e-027
sp|P52020|ERG1_RAT Squalene monooxygenase OS=Rattus norvegicus G... 116 1e-025
sp|Q9C1W3|ERG1_SCHPO Probable squalene monooxygenase OS=Schizosa... 116 2e-025
sp|O13306|ERG1_CANGA Squalene monooxygenase OS=Candida glabrata ... 85 4e-016
sp|Q75F69|ERG1_ASHGO Squalene monooxygenase OS=Ashbya gossypii G... 84 7e-016
sp|P32476|ERG1_YEAST Squalene monooxygenase OS=Saccharomyces cer... 82 3e-015
sp|Q92206|ERG1_CANAL Squalene monooxygenase OS=Candida albicans ... 75 2e-013
>sp|O48651|ERG1_PANGI Squalene monooxygenase OS=Panax ginseng PE=2 SV=1
Length = 539
Score = 210 bits (532), Expect = 1e-053
Identities = 102/127 (80%), Positives = 116/127 (91%), Gaps = 3/127 (2%)
Frame = +3
Query: 267 DNVA---DVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIE 437
+N+A DVI+VGAGVAGSALAYTL D RRVHVIERDL+E DRIVGELLQPGGYLKLIE
Sbjct: 69 ENIAGSTDVIIVGAGVAGSALAYTLANDGRRVHVIERDLTEQDRIVGELLQPGGYLKLIE 128
Query: 438 LGIEDCVEEIDAQRVYGYALFKNGKRIRLAYPLEKFHTDVSGRSFHNGRFIQRMREKAAS 617
LG+EDCV EIDAQRV+GYAL+ +GK RL+YPLEKFH+DV+GRSFHNGRF+QRMREKAAS
Sbjct: 129 LGLEDCVNEIDAQRVFGYALYMDGKNTRLSYPLEKFHSDVAGRSFHNGRFVQRMREKAAS 188
Query: 618 LPNVQLE 638
LPNV++E
Sbjct: 189 LPNVRME 195
>sp|O65404|ERG11_ARATH Squalene monooxygenase 1,1 OS=Arabidopsis thaliana
GN=SQP1,1 PE=2 SV=2
Length = 516
Score = 161 bits (405), Expect = 6e-039
Identities = 78/126 (61%), Positives = 98/126 (77%), Gaps = 2/126 (1%)
Frame = +3
Query: 267 DNVADVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIELGI 446
D DVI+VGAGV GSALAY L KD RRVHVIERDL EP+RI+GE +QPGG L L +LG+
Sbjct: 43 DGATDVIIVGAGVGGSALAYALAKDGRRVHVIERDLREPERIMGEFMQPGGRLMLSKLGL 102
Query: 447 EDCVEEIDAQRVYGYALFKNGKRIRLAYPLE--KFHTDVSGRSFHNGRFIQRMREKAASL 620
EDC+E IDAQ+ G ++K+GK ++P++ F D S RSFHNGRF+QR+R+KA+SL
Sbjct: 103 EDCLEGIDAQKATGMTVYKDGKEAVASFPVDNNNFPFDPSARSFHNGRFVQRLRQKASSL 162
Query: 621 PNVQLE 638
PNV+LE
Sbjct: 163 PNVRLE 168
>sp|O65726|ERG12_BRANA Squalene monooxygenase 1,2 OS=Brassica napus GN=SQP1,2
PE=2 SV=1
Length = 518
Score = 156 bits (392), Expect = 2e-037
Identities = 76/121 (62%), Positives = 96/121 (79%), Gaps = 1/121 (0%)
Frame = +3
Query: 279 DVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIELGIEDCV 458
DVI+VGAGV GSALAY L KD RRVHVIERD+ EP R++GE +QPGG L L +LG++DC+
Sbjct: 50 DVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPVRMMGEFMQPGGRLMLSKLGLQDCL 109
Query: 459 EEIDAQRVYGYALFKNGKRIRLAYPLE-KFHTDVSGRSFHNGRFIQRMREKAASLPNVQL 635
EEIDAQ+ G LFK+GK +P++ F + SGR FHNGRF+QR+R+KA+SLPNV+L
Sbjct: 110 EEIDAQKSTGIRLFKDGKETVACFPVDTNFPYEPSGRFFHNGRFVQRLRQKASSLPNVRL 169
Query: 636 E 638
E
Sbjct: 170 E 170
>sp|O65402|ERG12_ARATH Squalene monooxygenase 1,2 OS=Arabidopsis thaliana
GN=SQP1,2 PE=2 SV=1
Length = 517
Score = 154 bits (388), Expect = 5e-037
Identities = 74/126 (58%), Positives = 97/126 (76%), Gaps = 2/126 (1%)
Frame = +3
Query: 267 DNVADVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIELGI 446
D ADVI+VGAGV GSALAY L KD RRVHVIERD+ EP+R++GE +QPGG L L +LG+
Sbjct: 43 DGAADVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPERMMGEFMQPGGRLMLSKLGL 102
Query: 447 EDCVEEIDAQRVYGYALFKNGKRIRLAYPLE--KFHTDVSGRSFHNGRFIQRMREKAASL 620
+DC+E+IDAQ+ G A++K+GK +P++ F + S RSFHNGRF+Q++R KA SL
Sbjct: 103 QDCLEDIDAQKATGLAVYKDGKEADAPFPVDNNNFSYEPSARSFHNGRFVQQLRRKAFSL 162
Query: 621 PNVQLE 638
NV+LE
Sbjct: 163 SNVRLE 168
>sp|O65727|ERG11_BRANA Squalene monooxygenase 1,1 OS=Brassica napus GN=SQP1,1
PE=2 SV=1
Length = 506
Score = 149 bits (375), Expect = 2e-035
Identities = 73/125 (58%), Positives = 98/125 (78%), Gaps = 1/125 (0%)
Frame = +3
Query: 267 DNVADVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIELGI 446
D ADVI+VGAGV GSALAY L KD RRVHVIERD+ EP R++GE +QPGG L L +LG+
Sbjct: 45 DGDADVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPVRMMGEFMQPGGRLLLSKLGL 104
Query: 447 EDCVEEIDAQRVYGYALFKNGKRIRLAYPLEK-FHTDVSGRSFHNGRFIQRMREKAASLP 623
EDC+E ID Q G A++K+G++ +++P + F + +GR+F+NGRF+QR+R+KA+SLP
Sbjct: 105 EDCLEGIDEQIATGLAVYKDGQKALVSFPEDNDFPYEPTGRAFYNGRFVQRLRQKASSLP 164
Query: 624 NVQLE 638
VQLE
Sbjct: 165 TVQLE 169
>sp|O65403|ERG13_ARATH Squalene monooxygenase 2 OS=Arabidopsis thaliana GN=SQP2
PE=2 SV=1
Length = 516
Score = 146 bits (368), Expect = 1e-034
Identities = 73/125 (58%), Positives = 91/125 (72%), Gaps = 1/125 (0%)
Frame = +3
Query: 267 DNVADVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIELGI 446
D DVI+VGAGVAG++LAY L KD RRVHVIERDL EP R +GEL+Q GG L +LG+
Sbjct: 41 DGATDVIIVGAGVAGASLAYALAKDGRRVHVIERDLKEPQRFMGELMQAGGRFMLAQLGL 100
Query: 447 EDCVEEIDAQRVYGYALFKNGKRIRLAYPLEK-FHTDVSGRSFHNGRFIQRMREKAASLP 623
EDC+E+IDAQ A++K+GK L +P +K F + GR NGR +QR+R+KAASL
Sbjct: 101 EDCLEDIDAQEAKSLAIYKDGKHATLPFPDDKSFPHEPVGRLLRNGRLVQRLRQKAASLS 160
Query: 624 NVQLE 638
NVQLE
Sbjct: 161 NVQLE 165
>sp|Q14534|ERG1_HUMAN Squalene monooxygenase OS=Homo sapiens GN=SQLE PE=2 SV=3
Length = 574
Score = 124 bits (309), Expect = 8e-028
Identities = 65/123 (52%), Positives = 86/123 (69%), Gaps = 2/123 (1%)
Frame = +3
Query: 270 NVADVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIELGIE 449
N +VI+VGAGV GSALA L +D R+V VIERDL EPDRIVGE LQPGGY L +LG+
Sbjct: 122 NDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGLG 181
Query: 450 DCVEEIDAQRVYGYALF--KNGKRIRLAYPLEKFHTDVSGRSFHNGRFIQRMREKAASLP 623
D VE +DAQ V GY + ++ +++ YPL + + SGR+FH+GRFI +R+ A + P
Sbjct: 182 DTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAEP 241
Query: 624 NVQ 632
N +
Sbjct: 242 NAK 244
>sp|P52019|ERG1_MOUSE Squalene monooxygenase OS=Mus musculus GN=Sqle PE=2 SV=1
Length = 572
Score = 123 bits (308), Expect = 1e-027
Identities = 62/120 (51%), Positives = 87/120 (72%), Gaps = 2/120 (1%)
Frame = +3
Query: 279 DVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIELGIEDCV 458
+VI+VG+GV GSALA L +D R+V VIERDL EPDRIVGELLQPGGY L ELG+ D V
Sbjct: 123 EVIIVGSGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGELLQPGGYRVLQELGLGDTV 182
Query: 459 EEIDAQRVYGYAL--FKNGKRIRLAYPLEKFHTDVSGRSFHNGRFIQRMREKAASLPNVQ 632
E ++A ++GY + +++ +++ YPL + + SG +FH+GRFI +R+ A + PNV+
Sbjct: 183 EGLNAHHIHGYIVHDYESRSEVQIPYPLSETNQVQSGIAFHHGRFIMSLRKAAMAEPNVK 242
>sp|P52020|ERG1_RAT Squalene monooxygenase OS=Rattus norvegicus GN=Sqle PE=2
SV=1
Length = 573
Score = 116 bits (290), Expect = 1e-025
Identities = 60/140 (42%), Positives = 92/140 (65%), Gaps = 3/140 (2%)
Frame = +3
Query: 219 DRTVTSTVVSLNVRGGDNVADVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVG 398
+ T+T S++ + +VI++G+GV GSALA L +D R V VIERDL EPDRI+G
Sbjct: 105 ETTLTGAATSVSTSSVTD-PEVIIIGSGVLGSALATVLSRDGRTVTVIERDLKEPDRILG 163
Query: 399 ELLQPGGYLKLIELGIEDCVEEIDAQRVYGYALF--KNGKRIRLAYPLEKFHTDVSGRSF 572
E LQPGGY L ELG+ D VE ++A ++GY + ++ +++ YP+ + + SG +F
Sbjct: 164 ECLQPGGYRVLRELGLGDTVESLNAHHIHGYVIHDCESRSEVQIPYPVSENNQVQSGVAF 223
Query: 573 HNGRFIQRMREKAASLPNVQ 632
H+G+FI +R+ A + PNV+
Sbjct: 224 HHGKFIMSLRKAAMAEPNVK 243
>sp|Q9C1W3|ERG1_SCHPO Probable squalene monooxygenase OS=Schizosaccharomyces
pombe GN=SPBC713.12 PE=2 SV=1
Length = 457
Score = 116 bits (288), Expect = 2e-025
Identities = 57/118 (48%), Positives = 74/118 (62%)
Frame = +3
Query: 276 ADVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIELGIEDC 455
AD+I++GAG+ G AL LG+ R+V V+ERD+SEPDRIVGELLQPGG L ++GI D
Sbjct: 6 ADIIIIGAGITGCALGAALGRQGRKVLVLERDMSEPDRIVGELLQPGGIEALEKIGIADA 65
Query: 456 VEEIDAQRVYGYALFKNGKRIRLAYPLEKFHTDVSGRSFHNGRFIQRMREKAASLPNV 629
VE ID Q GY +F + + YP + G FH GRF+ +R+ S PNV
Sbjct: 66 VEGIDGQWTSGYQIFYGDSNVSVPYPSKPNGGAYQGIGFHYGRFVMNLRKALTSTPNV 123
>sp|O13306|ERG1_CANGA Squalene monooxygenase OS=Candida glabrata GN=ERG1 PE=3
SV=2
Length = 489
Score = 85 bits (208), Expect = 4e-016
Identities = 39/85 (45%), Positives = 56/85 (65%)
Frame = +3
Query: 279 DVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIELGIEDCV 458
D ++VGAGV G +A L + ++V ++ER+ S+PDRIVGEL+QPGG L LG+ +
Sbjct: 13 DALIVGAGVIGPCVATALARKGKKVLIVEREWSQPDRIVGELMQPGGLRALRSLGMIQSI 72
Query: 459 EEIDAQRVYGYALFKNGKRIRLAYP 533
IDA V GY +F NG+ + + YP
Sbjct: 73 NNIDAYPVTGYTVFYNGEHVDIPYP 97
>sp|Q75F69|ERG1_ASHGO Squalene monooxygenase OS=Ashbya gossypii GN=ERG1 PE=3
SV=1
Length = 497
Score = 84 bits (206), Expect = 7e-016
Identities = 41/87 (47%), Positives = 55/87 (63%)
Frame = +3
Query: 273 VADVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIELGIED 452
V D IVVGAGV G +A L + ++V ++ER+ S+PDRIVGEL+QP G L LG+
Sbjct: 19 VYDAIVVGAGVVGPCVATALARKGKKVLIVEREWSQPDRIVGELMQPAGVRALRSLGMVQ 78
Query: 453 CVEEIDAQRVYGYALFKNGKRIRLAYP 533
+ IDA GY + NG++I AYP
Sbjct: 79 AINNIDACSTSGYTVIYNGEKISFAYP 105
>sp|P32476|ERG1_YEAST Squalene monooxygenase OS=Saccharomyces cerevisiae GN=ERG1
PE=1 SV=2
Length = 496
Score = 82 bits (201), Expect = 3e-015
Identities = 39/85 (45%), Positives = 56/85 (65%)
Frame = +3
Query: 279 DVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIELGIEDCV 458
D IV+GAGV G +A L + ++V ++ERD + PDRIVGEL+QPGG L LG+ +
Sbjct: 20 DAIVIGAGVIGPCVATGLARKGKKVLIVERDWAMPDRIVGELMQPGGVRALRSLGMIQSI 79
Query: 459 EEIDAQRVYGYALFKNGKRIRLAYP 533
I+A V GY +F NG+++ + YP
Sbjct: 80 NNIEAYPVTGYTVFFNGEQVDIPYP 104
>sp|Q92206|ERG1_CANAL Squalene monooxygenase OS=Candida albicans GN=ERG1 PE=3
SV=1
Length = 496
Score = 75 bits (184), Expect = 2e-013
Identities = 38/88 (43%), Positives = 53/88 (60%)
Frame = +3
Query: 279 DVIVVGAGVAGSALAYTLGKDNRRVHVIERDLSEPDRIVGELLQPGGYLKLIELGIEDCV 458
D I++GAGV G +A + R+V ++ERD S+PDRIVGEL+QP G L ELG+ +
Sbjct: 7 DAIIIGAGVIGPTIATAFARQGRKVLIVERDWSKPDRIVGELMQPAGIKALRELGMIKAI 66
Query: 459 EEIDAQRVYGYALFKNGKRIRLAYPLEK 542
I A GY + + I + YPL+K
Sbjct: 67 NNIRAVDCTGYYIKYYDETITIPYPLKK 94
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0
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