BLASTX 7.6.2
Query= UN16975 /QuerySize=1518
(1517 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q503V9|ENDUB_DANRE Poly(U)-specific endoribonuclease-B OS=Dan... 160 3e-038
sp|B1H3D5|ENDOU_XENTR Poly(U)-specific endoribonuclease OS=Xenop... 150 4e-035
sp|Q8JFY9|ENDUA_XENLA Poly(U)-specific endoribonuclease-A OS=Xen... 149 5e-035
sp|B1WBB4|ENDUB_XENLA Poly(U)-specific endoribonuclease-B OS=Xen... 149 5e-035
sp|Q1LUM3|ENDUC_DANRE Poly(U)-specific endoribonuclease-C OS=Dan... 147 2e-034
sp|P21128|ENDOU_HUMAN Poly(U)-specific endoribonuclease OS=Homo ... 145 1e-033
sp|Q3V188|ENDOU_MOUSE Poly(U)-specific endoribonuclease OS=Mus m... 139 8e-032
sp|A6QLQ8|ENDOU_BOVIN Poly(U)-specific endoribonuclease OS=Bos t... 132 8e-030
sp|A1L237|ENDUA_DANRE Poly(U)-specific endoribonuclease-A OS=Dan... 127 3e-028
sp|Q9PTU6|ENDOU_PAROL Poly(U)-specific endoribonuclease OS=Paral... 118 1e-025
sp|Q9VZ49|ENDOU_DROME Poly(U)-specific endoribonuclease homolog ... 112 1e-023
sp|Q21109|ENDOU_CAEEL Poly(U)-specific endoribonuclease homolog ... 100 4e-020
>sp|Q503V9|ENDUB_DANRE Poly(U)-specific endoribonuclease-B OS=Danio rerio
GN=endoub PE=2 SV=1
Length = 282
Score = 160 bits (403), Expect = 3e-038
Identities = 80/193 (41%), Positives = 110/193 (56%), Gaps = 5/193 (2%)
Frame = +3
Query: 759 EVVTEEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRGG 938
E+VT EE E F++ + +T +K HKYL K ++P FK+ L +WF+LY R G
Sbjct: 86 EIVTPEEEMENHRFLDSVIKTPTMKIAHKYLVEKRLSPEDTTGFKQQLYKIWFELYARKG 145
Query: 939 TS-GSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRLGEIPDS 1115
+S SS FEHVFVGE + GG V GFHNW+Q YL+E G +DY+GY + PD
Sbjct: 146 SSKPDSSGFEHVFVGETR--GGHTVIGFHNWIQLYLQEKLGHIDYKGYSVNANSPQ-PDE 202
Query: 1116 ETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFMG-REDNHIQLGPYCVNVKCY 1292
+L +QF W +K S +GVSPEFE +LYT+CF M E + Y V + C+
Sbjct: 203 NKHMLALQFSWKNGIKPKGSIFIGVSPEFEFSLYTLCFLMSPNERVKVSFNLYDVEIVCH 262
Query: 1293 RLGNNRIGSAFPI 1331
IG+ +P+
Sbjct: 263 HYNQKHIGTTYPV 275
>sp|B1H3D5|ENDOU_XENTR Poly(U)-specific endoribonuclease OS=Xenopus tropicalis
GN=endou PE=2 SV=1
Length = 293
Score = 150 bits (377), Expect = 4e-035
Identities = 81/195 (41%), Positives = 118/195 (60%), Gaps = 8/195 (4%)
Frame = +3
Query: 759 EVVTEEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRG- 935
EVVT EE E F++ I T V+K H YL K+ A S +FK L ++WF LY R
Sbjct: 93 EVVTPEEIAENNTFLDAILETKVMKIAHDYLVRKNQAKPSRNDFKAQLYTIWFQLYSRAP 152
Query: 936 GTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRLGEIPDS 1115
G S FEHVFVGE K+ G+++ G HNW+QFYL+E + ++DY+GY+ R+ PD
Sbjct: 153 GQGPDSCGFEHVFVGESKR--GKEIMGLHNWVQFYLQEKRKTIDYKGYV-GRQNKSRPDH 209
Query: 1116 ETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFMGRED---NHIQLGPYCVNVK 1286
+ Q+L +QF W ++K + S+ +GVSPEFE ALYT+ F +E +++ Y + +
Sbjct: 210 DDQVLNLQFSWKEMVKPIGSSFIGVSPEFEFALYTVVFLTSQEKMTREVVRVEEYEMQIV 269
Query: 1287 CYRLGNNRIGSAFPI 1331
R G IG+A+P+
Sbjct: 270 VNRHG-RYIGTAYPV 283
>sp|Q8JFY9|ENDUA_XENLA Poly(U)-specific endoribonuclease-A OS=Xenopus laevis
GN=endou-a PE=1 SV=1
Length = 292
Score = 149 bits (376), Expect = 5e-035
Identities = 82/195 (42%), Positives = 119/195 (61%), Gaps = 8/195 (4%)
Frame = +3
Query: 759 EVVTEEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRG- 935
EVVT EE E F++ I T V+K H YL K+ A + +FK L ++WF LY R
Sbjct: 92 EVVTPEEIAENNNFLDAILETKVMKMAHDYLVRKNQAKPTRNDFKVQLYNIWFQLYSRAP 151
Query: 936 GTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRLGEIPDS 1115
G+ S FEHVFVGE K+ G+++ G HNW+QFYL+E + ++DY+GY+ R+ PD
Sbjct: 152 GSRPDSCGFEHVFVGESKR--GQEMMGLHNWVQFYLQEKRKNIDYKGYV-ARQNKSRPDE 208
Query: 1116 ETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFMGRED---NHIQLGPYCVNVK 1286
+ Q+L +QF W ++K V S+ +GVSPEFE ALYT+ F +E ++L Y + +
Sbjct: 209 DDQVLNLQFNWKEMVKPVGSSFIGVSPEFEFALYTIVFLASQEKMSREVVRLEEYELQIV 268
Query: 1287 CYRLGNNRIGSAFPI 1331
R G IG+A+P+
Sbjct: 269 VNRHG-RYIGTAYPV 282
>sp|B1WBB4|ENDUB_XENLA Poly(U)-specific endoribonuclease-B OS=Xenopus laevis
GN=endou-b PE=2 SV=1
Length = 292
Score = 149 bits (376), Expect = 5e-035
Identities = 87/196 (44%), Positives = 119/196 (60%), Gaps = 12/196 (6%)
Frame = +3
Query: 759 EVVTEEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRG- 935
EVVT EE E F++ I T V+K H YL K+ A S +FK L S+WF LY R
Sbjct: 92 EVVTPEEIAENNNFLDAILETKVMKMAHDYLVRKNQAKPSQNDFKVQLYSIWFQLYSRAP 151
Query: 936 GTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRLGEIPDS 1115
G+ S FEHVFVGE K+ G+++ G HNW+QFYL+E + ++DY+GY+ R+ PD
Sbjct: 152 GSRPDSCGFEHVFVGESKR--GKEMMGLHNWVQFYLQEKRKNIDYKGYV-ARQNKSRPDE 208
Query: 1116 ETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFF-----MGREDNHIQLGPYCVN 1280
+ Q+L +QF W ++K V S+ +GVSPEFE ALYT+ F M RE I+L Y +
Sbjct: 209 DDQVLNLQFSWKEMVKPVGSSFIGVSPEFEFALYTIVFLASQAKMSRE--VIRLEEYELQ 266
Query: 1281 VKCYRLGNNRIGSAFP 1328
+ R G IG+A+P
Sbjct: 267 IVVNRHG-RYIGTAYP 281
>sp|Q1LUM3|ENDUC_DANRE Poly(U)-specific endoribonuclease-C OS=Danio rerio
GN=endouc PE=2 SV=1
Length = 309
Score = 147 bits (370), Expect = 2e-034
Identities = 81/194 (41%), Positives = 117/194 (60%), Gaps = 9/194 (4%)
Frame = +3
Query: 759 EVVTEEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRGG 938
E VT EE E +F++ I TAV+K H+YL K + ++FK L +WF LY R
Sbjct: 111 ERVTAEEVTENNSFLDAILETAVMKRAHQYLIGKGKSRSDLRQFKSQLYYMWFRLYHRER 170
Query: 939 TSG-SSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRLGEIPDS 1115
G SS FEHVFVGE K G ++ G HNW+QFYL+E + +DY+GY R ++PD+
Sbjct: 171 NGGEDSSGFEHVFVGETK--FGREIMGLHNWVQFYLQEKQNLLDYKGY--KARANDVPDA 226
Query: 1116 ETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFMGREDNH---IQLGPYCVNVK 1286
+ +L +QF W+G++K V+S VGVSPEFE+A++T+ F E + L Y + +
Sbjct: 227 DDHVLNVQFSWHGLVKPVASAFVGVSPEFEMAVFTILFLTSTEKTTTAVVNLDEYQLEMV 286
Query: 1287 CYRLGNNRIGSAFP 1328
+R G IG+A+P
Sbjct: 287 VHRHG-RCIGTAYP 299
>sp|P21128|ENDOU_HUMAN Poly(U)-specific endoribonuclease OS=Homo sapiens
GN=ENDOU PE=1 SV=2
Length = 410
Score = 145 bits (364), Expect = 1e-033
Identities = 82/194 (42%), Positives = 115/194 (59%), Gaps = 11/194 (5%)
Frame = +3
Query: 744 ARSYKEVVTEEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDL 923
A + E + +E EQ AF+ EI +TAV+K L+ +L ++ GS QEF L ++WF L
Sbjct: 212 ATGHGEHFSAQELAEQDAFLREIMKTAVMKELYSFLHHQN-RYGSEQEFVDDLKNMWFGL 270
Query: 924 YGRGGTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRLGE 1103
Y RG G SS FEHVF GE+K+ +V+GFHNW++FYLEE +G VDY +I+
Sbjct: 271 YSRGNEEGDSSGFEHVFSGEVKK---GKVTGFHNWIRFYLEEKEGLVDYYSHIYDGPWDS 327
Query: 1104 IPDSETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFMGREDN--HIQLGPYCV 1277
PD +L +QF W+G K V S +G SPEFE ALY++C F+ R + LG Y +
Sbjct: 328 YPD----VLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLC-FIARPGKVCQLSLGGYPL 382
Query: 1278 NVKCYRLGNNRIGS 1319
V+ Y + G+
Sbjct: 383 AVRTYTWDKSTYGN 396
>sp|Q3V188|ENDOU_MOUSE Poly(U)-specific endoribonuclease OS=Mus musculus
GN=Endou PE=2 SV=1
Length = 412
Score = 139 bits (348), Expect = 8e-032
Identities = 74/193 (38%), Positives = 112/193 (58%), Gaps = 9/193 (4%)
Frame = +3
Query: 744 ARSYKEVVTEEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDL 923
A + E + ++ +EQ F+ E+ +TAV+K L+ +L ++ S QEF L ++WF L
Sbjct: 213 ATGHGEHFSAQQLEEQGVFLREVMKTAVMKELYSFLHHQN-RYSSEQEFVDDLKNMWFGL 271
Query: 924 YGRGGTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRLGE 1103
Y RG G SS FEHVF GE+K+ +V+GFHNW++FYL+E +G +DY + +
Sbjct: 272 YSRGNDEGDSSGFEHVFSGEVKK---GKVTGFHNWIRFYLQEKEGLLDYYSHNYDGPWDS 328
Query: 1104 IPDSETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFF-MGREDNHIQLGPYCVN 1280
PD +L +QF W+G K V S +G SPEFE ALY++CF + H+ LG Y +
Sbjct: 329 YPD----VLAMQFNWDGYYKEVGSVFIGSSPEFEFALYSLCFITRPGKKCHLSLGGYPLA 384
Query: 1281 VKCYRLGNNRIGS 1319
++ Y G+
Sbjct: 385 IQTYTWDKTTYGN 397
>sp|A6QLQ8|ENDOU_BOVIN Poly(U)-specific endoribonuclease OS=Bos taurus GN=ENDOU
PE=2 SV=1
Length = 413
Score = 132 bits (331), Expect = 8e-030
Identities = 75/202 (37%), Positives = 111/202 (54%), Gaps = 16/202 (7%)
Frame = +3
Query: 759 EVVTEEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRGG 938
E T +E EQ F+ EI +TAV+K L+ +L ++ S QEF L ++WF LY R
Sbjct: 219 EHFTAQELAEQDTFLREIMKTAVMKELYGFLHQQN-RYSSEQEFVSDLKNMWFGLYSRSK 277
Query: 939 TSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRLGEIPDSE 1118
SS FEHVF GE+K+ +V+GFHNW++FY++E +G VDY +I+ PD
Sbjct: 278 EERDSSGFEHVFSGEVKK---GKVTGFHNWIRFYMQEKEGLVDYYSHIYDGPWDSYPD-- 332
Query: 1119 TQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFF--------MGREDNHIQLGPYC 1274
+L +QF W+G K V S +G SPEFE ALY++CF + + + + Y
Sbjct: 333 --VLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIARPGKVCQLSLGGHPLAIQTYT 390
Query: 1275 VNVKCYRLGNNRIGSAFPIAES 1340
N Y G I +A+ ++ +
Sbjct: 391 WNKSTYGNGKKYIATAYVVSST 412
>sp|A1L237|ENDUA_DANRE Poly(U)-specific endoribonuclease-A OS=Danio rerio
GN=endoua PE=2 SV=1
Length = 303
Score = 127 bits (318), Expect = 3e-028
Identities = 78/201 (38%), Positives = 113/201 (56%), Gaps = 19/201 (9%)
Frame = +3
Query: 759 EVVTEEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRG- 935
E V E QEQ +F+++ T + K L +L K V GS EF + L +WF LY R
Sbjct: 110 EDVPSHEEQEQDSFLQQTMNTNLGKELFNFLHSKGVY-GSQSEFLQDLKMMWFGLYSRSD 168
Query: 936 GTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRLGEIPDS 1115
G SS FEH+FVGEIK G +VSGFH+W+QFY E +G ++Y + F PD
Sbjct: 169 GVKLDSSGFEHIFVGEIK---GGKVSGFHSWVQFYQCEKQGILNYYSHSFDGPWTTYPD- 224
Query: 1116 ETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFM--GREDNHIQLGPYCVNVKC 1289
+L +QF W+G K + S +G SPEF+LA+Y++C+ G++ + + LG + + ++
Sbjct: 225 ---VLGMQFNWDGYFKELGSAFIGCSPEFDLAIYSLCYITRPGKKCD-VSLGGHSLGIQT 280
Query: 1290 YRL-------GNNRIGSAFPI 1331
Y G IGSA+PI
Sbjct: 281 YTWDKSSYGDGKKFIGSAYPI 301
>sp|Q9PTU6|ENDOU_PAROL Poly(U)-specific endoribonuclease OS=Paralichthys
olivaceus GN=endou PE=2 SV=1
Length = 385
Score = 118 bits (295), Expect = 1e-025
Identities = 75/201 (37%), Positives = 106/201 (52%), Gaps = 21/201 (10%)
Frame = +3
Query: 759 EVVTEEERQEQAAFIEE-ISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRG 935
E + ++ EQ FI+E +S T + + L +L K V S EF L +WF LY R
Sbjct: 192 EDFSPQQLSEQETFIKEAMSNTELGRELFAFLYTKGVY-ASENEFLHDLKMMWFGLYSRY 250
Query: 936 GTSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRLGEIPDS 1115
SS FEH+F GEIK G +VSGFHNW+QFY E +G ++Y + F PD
Sbjct: 251 NNKMDSSGFEHIFAGEIK---GGKVSGFHNWIQFYRLEKRGQLNYYSHSFNGPWTTFPD- 306
Query: 1116 ETQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFF----------MGREDNHIQLG 1265
++ +QF+W+G K V S ++G SPEF+ ALY++C+ +G ++ IQ
Sbjct: 307 ---VMGMQFKWDGYFKQVGSAVIGCSPEFDFALYSLCYITRPGKQCRLSLGGKELIIQ-- 361
Query: 1266 PYCVNVKCYRLGNNRIGSAFP 1328
Y + Y G I SAFP
Sbjct: 362 TYTWDKTTYGNGKKFIASAFP 382
>sp|Q9VZ49|ENDOU_DROME Poly(U)-specific endoribonuclease homolog OS=Drosophila
melanogaster GN=CG2145 PE=1 SV=1
Length = 592
Score = 112 bits (278), Expect = 1e-023
Identities = 71/195 (36%), Positives = 104/195 (53%), Gaps = 13/195 (6%)
Frame = +3
Query: 759 EVVTEEERQEQAAFIEEISRTAVVKYLHKYLAIKDVAPGSYQEFKRMLTSLWFDLYGRGG 938
E VT ER+E+ F++ + T V++ +L K V + + ++ LWF Y RG
Sbjct: 404 EHVTPNERKEENDFLDAVMATPVMRQAMLFLQQKGVVSPDPKTHRDLVKELWFTQYSRGQ 463
Query: 939 TSGSSSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEEAKGSVDYQGYIFPRRLGEIPDSE 1118
SS FEHVFV E+K + GFHNW+ EE G DY+GY+ + +G ++
Sbjct: 464 GKIGSSGFEHVFVYEVKD---GTIIGFHNWVYIGDEEKDGRFDYKGYMKEQDIG----TK 516
Query: 1119 TQLLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFFMGREDN--HIQLGPYCVNVKCY 1292
+++ I+F G+ K V++ VG SPE ELALYT+CF + R D + LG + Y
Sbjct: 517 GKIVKIRFSHQGLNKPVNTVFVGTSPELELALYTVCFQL-RPDRTCPVSLGNSKFGIVTY 575
Query: 1293 R---LGNNRIGSAFP 1328
G N IGSA+P
Sbjct: 576 SWRYRGKNLIGSAYP 590
>sp|Q21109|ENDOU_CAEEL Poly(U)-specific endoribonuclease homolog
OS=Caenorhabditis elegans GN=K02A11.3 PE=1 SV=1
Length = 307
Score = 100 bits (247), Expect = 4e-020
Identities = 62/195 (31%), Positives = 98/195 (50%), Gaps = 19/195 (9%)
Frame = +3
Query: 774 EERQEQAAFIEEISRTAVVKYLHKYLAIK-DVAPGSYQEFKRMLTSLWFDLYGRGGTSGS 950
EE+ E F++ + + ++ L+ + K S Q F+ + LWF Y R
Sbjct: 110 EEKNEVGKFLDYVLESRPMQELYNWFKAKGHPIATSPQVFRFWIGQLWFSHYSRALGRPD 169
Query: 951 SSAFEHVFVGEIKQCGGEQVSGFHNWLQFYLEE--AKGSVDYQGYIFPRRLGEIPDSETQ 1124
+S FEHVF+GE K ++SG HNW++FY+ E + DY+G+ R
Sbjct: 170 TSGFEHVFIGEAK---NGEISGMHNWVRFYVLENNRTENFDYKGFTVKR--------FNI 218
Query: 1125 LLTIQFEWNGVLKSVSSTLVGVSPEFELALYTMCFF--MGREDNHIQLGPYCVNVKCYRL 1298
+ ++F W+G+LK S L+G SPEF++ALYTMCF GRE ++ + + + +
Sbjct: 219 MAALKFTWDGLLKRAGSILIGTSPEFDMALYTMCFLSRRGRETCDVEFDGCPLQITSFEI 278
Query: 1299 GNNR---IGSAFPIA 1334
IGS +P A
Sbjct: 279 MQQNKVYIGSIYPTA 293
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0
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