BLASTX 7.6.2
Query= UN16977 /QuerySize=1316
(1315 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54WM0|T1843_DICDI Transmembrane protein 184 homolog DDB_G027... 150 2e-035
sp|Q3TPR7|T184C_MOUSE Transmembrane protein 184C OS=Mus musculus... 148 9e-035
sp|Q9NVA4|T184C_HUMAN Transmembrane protein 184C OS=Homo sapiens... 146 6e-034
sp|Q5RET6|T184C_PONAB Transmembrane protein 184C OS=Pongo abelii... 146 6e-034
sp|Q6GQE1|T184C_XENLA Transmembrane protein 184C OS=Xenopus laev... 146 6e-034
sp|Q5ZMP3|T184C_CHICK Transmembrane protein 184C OS=Gallus gallu... 145 1e-033
sp|Q28CV2|T184C_XENTR Transmembrane protein 184C OS=Xenopus trop... 145 1e-033
sp|Q17QL9|T184C_BOVIN Transmembrane protein 184C OS=Bos taurus G... 144 1e-033
sp|Q810F5|T184C_RAT Transmembrane protein 184C OS=Rattus norvegi... 144 2e-033
sp|Q54PI4|T1841_DICDI Transmembrane protein 184 homolog DDB_G028... 139 5e-032
sp|Q9Y519|T184B_HUMAN Transmembrane protein 184B OS=Homo sapiens... 136 6e-031
sp|A2VDL9|T184B_BOVIN Transmembrane protein 184B OS=Bos taurus G... 135 1e-030
sp|Q6ZMB5|T184A_HUMAN Transmembrane protein 184A OS=Homo sapiens... 134 1e-030
sp|Q3UFJ6|T184A_MOUSE Transmembrane protein 184A OS=Mus musculus... 133 4e-030
sp|Q4QQS1|T184A_RAT Transmembrane protein 184A OS=Rattus norvegi... 133 4e-030
sp|Q8BG09|T184B_MOUSE Transmembrane protein 184B OS=Mus musculus... 132 5e-030
sp|Q1RMW2|T184A_BOVIN Transmembrane protein 184A OS=Bos taurus G... 89 6e-017
sp|Q09906|TM184_SCHPO Transmembrane protein 184 homolog C30D11.0... 79 5e-014
sp|P36142|TM184_YEAST Transmembrane protein 184 homolog YKR051W ... 64 2e-009
sp|Q75JN3|T1842_DICDI Transmembrane protein 184 homolog DDB_G027... 56 5e-007
>sp|Q54WM0|T1843_DICDI Transmembrane protein 184 homolog DDB_G0279555
OS=Dictyostelium discoideum GN=tmem184C PE=3 SV=1
Length = 351
Score = 150 bits (378), Expect = 2e-035
Identities = 93/257 (36%), Positives = 145/257 (56%), Gaps = 23/257 (8%)
Frame = +2
Query: 320 ITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSEIFFLFLESI 499
+ +LL+ L+ +HL ++ NP+ QK I+ I++M PIY+V S++ L V+ S L+ + +
Sbjct: 11 VAILLSFYLIYKHLRNYTNPELQKYIVRILIMVPIYSVDSWLSLRFVELS----LYFDVV 66
Query: 500 KECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHVVRLDHRTLR 679
++ YEA V+ F +L+ +Y+ ++V + H FP+T ++LD L
Sbjct: 67 RDTYEAYVLYCFFSLIVAYIERDF--DLVELLHSKEPLPHPFPLTCLPK--IKLDRGFLT 122
Query: 680 LLKYWTWQFVVIRPVCSILMIALQI----------IGFYPSWLSWTFTIVLNLSVSLALY 829
K + QFV I+P+ +I+ + L+ +G WL T+V N+SV L+LY
Sbjct: 123 NCKRFVLQFVFIKPIVAIISLVLETQHKYGEGKFQVGTGYVWL----TVVENISVGLSLY 178
Query: 830 SLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVIKSHHFWLEVEQI 1009
LV++Y +EL P PL KFLCIK I+FF FWQ IA+ LV GVI W V+ I
Sbjct: 179 FLVLYYKAMEEELKPFKPLGKFLCIKSILFFSFWQSIAISFLVYFGVISPIGSW-SVDNI 237
Query: 1010 QEAIQNVLVCLEMVIFA 1060
A+Q+ + C+EMVI A
Sbjct: 238 SSALQDFITCVEMVILA 254
>sp|Q3TPR7|T184C_MOUSE Transmembrane protein 184C OS=Mus musculus GN=Tmem184c
PE=2 SV=1
Length = 525
Score = 148 bits (373), Expect = 9e-035
Identities = 86/283 (30%), Positives = 153/283 (54%), Gaps = 15/283 (5%)
Frame = +2
Query: 290 TFYCSALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGS 469
+++ + + + +T+ ++L + QHL H+ P+ QK I+ I+ M PIY+V S+V L+ K
Sbjct: 48 SWFIAGIFLLLTIPVSLWGILQHLVHYTQPELQKPIIRILWMVPIYSVDSWVALVYPK-- 105
Query: 470 EIFFLFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPH 649
+++++ +ECYEA VI F+ + +YL I I+ K ++ +H P+ P
Sbjct: 106 --IAIYVDTWRECYEAYVIYNFMIFLTNYLTIRFPNLILHLEAKDQQ-NHILPLCCCPPW 162
Query: 650 VVRLDHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFYPSW-----LSWTFTIVL-NLS 811
+ L K Q+ V+RP+ ++ + +I+ Y +WT+ ++L NLS
Sbjct: 163 A--MGEMLLFRCKLGVLQYTVVRPITTVTALVCEILDVYDEGNFGFSNAWTYLVILNNLS 220
Query: 812 VSLALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVI--KSHH 985
A+Y L++FY V +EL+P P+ KFLC+K +VF FWQ + + +LV +GVI K
Sbjct: 221 QLFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVLIALLVKLGVISEKRTW 280
Query: 986 FWLEVEQIQEAIQNVLVCLEMVIFAAVQKHAYHVGPYSGETKK 1114
W E + +Q+ ++C+EM A + + PY E ++
Sbjct: 281 EWQSAEAVATGLQDFIICIEMFFAAIAHHYTFSYKPYVHEAEE 323
>sp|Q9NVA4|T184C_HUMAN Transmembrane protein 184C OS=Homo sapiens GN=TMEM184C
PE=2 SV=2
Length = 438
Score = 146 bits (366), Expect = 6e-034
Identities = 83/282 (29%), Positives = 153/282 (54%), Gaps = 15/282 (5%)
Frame = +2
Query: 293 FYCSALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSE 472
++ + + + +T+ ++L ++ QHL H+ P+ QK I+ I+ M PIY++ S++ L G
Sbjct: 49 WFIAGIFLLLTIPISLWVILQHLVHYTQPELQKPIIRILWMVPIYSLDSWIA-LKYPGIA 107
Query: 473 IFFLFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHV 652
I ++++ +ECYEA VI F+ + +YL ++ K ++ H P+ P
Sbjct: 108 I---YVDTCRECYEAYVIYNFMGFLTNYLTNRYPNLVLILEAKDQQKHFP-PLCCCPPWA 163
Query: 653 VRLDHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFYPSW-----LSWTFTIVL-NLSV 814
+ L K Q+ V+RP +I+ + +++G Y +WT+ +++ N+S
Sbjct: 164 --MGEVLLFRCKLGVLQYTVVRPFTTIVALICELLGIYDEGNFSFSNAWTYLVIINNMSQ 221
Query: 815 SLALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVIKSHHF-- 988
A+Y L++FY V +EL+P P+ KFLC+K +VF FWQ + + +LV +GVI H
Sbjct: 222 LFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVVIALLVKVGVISEKHTWE 281
Query: 989 WLEVEQIQEAIQNVLVCLEMVIFAAVQKHAYHVGPYSGETKK 1114
W VE + +Q+ ++C+EM + A + + PY E ++
Sbjct: 282 WQTVEAVATGLQDFIICIEMFLAAIAHHYTFSYKPYVQEAEE 323
>sp|Q5RET6|T184C_PONAB Transmembrane protein 184C OS=Pongo abelii GN=TMEM184C
PE=2 SV=1
Length = 438
Score = 146 bits (366), Expect = 6e-034
Identities = 83/282 (29%), Positives = 153/282 (54%), Gaps = 15/282 (5%)
Frame = +2
Query: 293 FYCSALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSE 472
++ + + + +T+ ++L ++ QHL H+ P+ QK I+ I+ M PIY++ S++ L G
Sbjct: 49 WFIAGIFLLLTIPISLWVILQHLVHYTQPELQKPIIRILWMVPIYSLDSWIA-LKYPGIA 107
Query: 473 IFFLFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHV 652
I ++++ +ECYEA VI F+ + +YL ++ K ++ H P+ P
Sbjct: 108 I---YVDTCRECYEAYVIYNFMGFLTNYLTNRYPNLVLILEAKDQQKHFP-PLCCCPPWA 163
Query: 653 VRLDHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFYPSW-----LSWTFTIVL-NLSV 814
+ L K Q+ V+RP +I+ + +++G Y +WT+ +++ N+S
Sbjct: 164 --MGEVLLFRCKLGVLQYTVVRPFTTIVALICELLGIYDEGNFSFSNAWTYLVIINNMSQ 221
Query: 815 SLALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVIKSHHF-- 988
A+Y L++FY V +EL+P P+ KFLC+K +VF FWQ + + +LV +GVI H
Sbjct: 222 LFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVVIALLVKVGVISEKHTWE 281
Query: 989 WLEVEQIQEAIQNVLVCLEMVIFAAVQKHAYHVGPYSGETKK 1114
W VE + +Q+ ++C+EM + A + + PY E ++
Sbjct: 282 WQTVEAVATGLQDFIICIEMFLAAIAHHYTFSYKPYVQEAEE 323
>sp|Q6GQE1|T184C_XENLA Transmembrane protein 184C OS=Xenopus laevis GN=tmem184c
PE=2 SV=1
Length = 444
Score = 146 bits (366), Expect = 6e-034
Identities = 86/280 (30%), Positives = 152/280 (54%), Gaps = 13/280 (4%)
Frame = +2
Query: 293 FYCSALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSE 472
++ + + V +T+ ++L + QHL H+ P+ QK I+ I+ M PIY+V S++ L K +
Sbjct: 47 WFIAGIFVLMTIPISLWGILQHLVHYTQPELQKPIIRILWMVPIYSVDSWIAL---KYPD 103
Query: 473 IFFLFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHV 652
I +++++ +ECYEA VI F+ + +YL + K ++ H P+ P
Sbjct: 104 I-AIYVDTCRECYEAYVIYNFMIFLLNYLTNRCPNLALVLEAKDQQ-RHLPPLCCCPPWA 161
Query: 653 VRLDHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFYPSW-----LSWTFTIVL-NLSV 814
+ L K Q+ V+RPV +++ + Q+ G Y +WT+ +++ N+S
Sbjct: 162 --MGDVLLFRCKLGVLQYTVVRPVTTVIALICQLTGVYGEGDFSVKNAWTYLVIINNVSQ 219
Query: 815 SLALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVIKSHHFWL 994
A+Y LV+FY V +EL P P+ KFLC+K +VF FWQ + + ILV GVI + W
Sbjct: 220 VFAMYCLVLFYKVLKEELNPIQPVGKFLCVKMVVFVSFWQAVFIAILVKAGVISNTWEWK 279
Query: 995 EVEQIQEAIQNVLVCLEMVIFAAVQKHAYHVGPYSGETKK 1114
V+ + +Q+ ++C+EM + A +++ PY E ++
Sbjct: 280 RVQDVATGLQDFIICVEMFLAAVAHHYSFTYKPYVQEAEE 319
>sp|Q5ZMP3|T184C_CHICK Transmembrane protein 184C OS=Gallus gallus GN=TMEM184C
PE=2 SV=1
Length = 445
Score = 145 bits (364), Expect = 1e-033
Identities = 93/314 (29%), Positives = 165/314 (52%), Gaps = 17/314 (5%)
Frame = +2
Query: 203 LLQLLFFSGFWGF*AFAMMDLTKLKPPQIT--FYCSALSVFITVLLTLQLVSQHLSHWKN 376
L+ LL+ G + +L KL+ T ++ + + + +T+ ++L + QHL H+
Sbjct: 15 LVVLLYIVGLLVVVPLCVWELQKLEVGIHTKAWFIAGIFLLMTIPISLWGILQHLVHYTQ 74
Query: 377 PKEQKAILIIVLMAPIYAVVSFVGLLDVKGSEIFFLFLESIKECYEALVIAKFLALMYSY 556
P+ QK I+ I+ M PIY++ S++ L K I +++++ +ECYEA VI F+ + +Y
Sbjct: 75 PELQKPIIRILWMVPIYSLDSWIAL---KYPNI-AIYVDTCRECYEAYVIYNFMVFLSNY 130
Query: 557 LNISISKNIVPDGIKGREIHHSFPMTFFQPHVVRLDHRTLRLLKYWTWQFVVIRPVCSIL 736
L ++ K ++ H P P + L K Q+ V+RP +I+
Sbjct: 131 LTNRYPNLVLIIEAKDQQRH--LPPLCCCPSWA-MGEVLLFRCKLGVLQYTVVRPFTTII 187
Query: 737 MIALQIIGFYPSW-----LSWTFTIVL-NLSVSLALYSLVVFYHVFAKELAPHNPLAKFL 898
+ +++G Y +WT+ ++L N+S A+Y LV+FY V +EL P P+ KFL
Sbjct: 188 ALICELVGVYDEGNFSFDNAWTYLVILNNMSQLFAMYCLVLFYKVLREELNPIQPVGKFL 247
Query: 899 CIKGIVFFCFWQGIALDILVAMGVIKSHHF--WLEVEQIQEAIQNVLVCLEMVIFAAVQK 1072
C+K +VF FWQ + + +LV +GVI H W VE + +Q+ ++C+EM + A
Sbjct: 248 CVKMVVFVSFWQAVLIALLVKVGVISEKHTWEWQSVEAVATGLQDFIICVEMFLAAIAHH 307
Query: 1073 HAYHVGPYSGETKK 1114
+++ PY E ++
Sbjct: 308 YSFSYKPYVQEAEE 321
>sp|Q28CV2|T184C_XENTR Transmembrane protein 184C OS=Xenopus tropicalis
GN=tmem184c PE=2 SV=1
Length = 443
Score = 145 bits (364), Expect = 1e-033
Identities = 86/280 (30%), Positives = 152/280 (54%), Gaps = 13/280 (4%)
Frame = +2
Query: 293 FYCSALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSE 472
++ + + V +T+ ++L + QHL H+ P+ QK I+ I+ M PIY+V S++ L K +
Sbjct: 47 WFIAGIFVLMTIPISLWGILQHLVHYTQPELQKPIIRILWMVPIYSVDSWIAL---KYPD 103
Query: 473 IFFLFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHV 652
I +++++ +ECYEA VI F+ + +YL + K ++ H P+ P
Sbjct: 104 I-AIYVDTCRECYEAYVIYNFMIFLLNYLTNRCPNLALVLEAKDQQ-RHLPPLCCCPPWA 161
Query: 653 VRLDHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFYPSW-----LSWTFTIVL-NLSV 814
+ L K Q+ V+RPV +++ + Q+ G Y +WT+ +++ N+S
Sbjct: 162 --MGDVLLFRCKLGVLQYTVVRPVTTVIALICQLTGVYGEGDFSVKNAWTYLVIINNVSQ 219
Query: 815 SLALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVIKSHHFWL 994
A+Y LV+FY V +EL P P+ KFLC+K +VF FWQ + + ILV GVI + W
Sbjct: 220 VFAMYCLVLFYKVLKEELNPIQPVGKFLCVKMVVFVSFWQAVFIAILVKAGVISNTWEWK 279
Query: 995 EVEQIQEAIQNVLVCLEMVIFAAVQKHAYHVGPYSGETKK 1114
+V+ + +Q+ ++C+EM + A ++ PY E ++
Sbjct: 280 KVQDVATGLQDFIICVEMFLAAVAHHFSFTYKPYVQEAEE 319
>sp|Q17QL9|T184C_BOVIN Transmembrane protein 184C OS=Bos taurus GN=TMEM184C PE=2
SV=1
Length = 438
Score = 144 bits (363), Expect = 1e-033
Identities = 82/282 (29%), Positives = 153/282 (54%), Gaps = 15/282 (5%)
Frame = +2
Query: 293 FYCSALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSE 472
++ + + + +T+ ++L ++ QHL H+ P+ QK I+ I+ M PIY++ S++ L K
Sbjct: 49 WFIAGIFLLLTIPISLWVILQHLVHYTQPELQKPIIRILWMVPIYSLDSWIAL---KYPS 105
Query: 473 IFFLFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHV 652
I +++++ +ECYEA VI F+ + +YL ++ K ++ H P+ P
Sbjct: 106 I-AIYVDTCRECYEAYVIYNFMGFLTNYLTNRYPNLVLIIEAKDQQKHFP-PLCCCPPWT 163
Query: 653 VRLDHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFYPSW-----LSWTFTIVL-NLSV 814
+ L K Q+ V+RP +I+ + +++ Y +WT+ +++ N+S
Sbjct: 164 --MGEVLLFRCKLGVLQYTVVRPFTTIIALVCELLDIYDEGNFSFSNAWTYLVIINNMSQ 221
Query: 815 SLALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVIKSHHF-- 988
A+Y L++FY V +EL+P P+ KFLC+K +VF FWQ + + +LV +GVI H
Sbjct: 222 LFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVVIALLVKVGVISEKHTWE 281
Query: 989 WLEVEQIQEAIQNVLVCLEMVIFAAVQKHAYHVGPYSGETKK 1114
W VE + +Q+ ++C+EM + A + + PY E ++
Sbjct: 282 WQTVEAVATGLQDFIICIEMFLAAIAHHYTFSYKPYVQEAEE 323
>sp|Q810F5|T184C_RAT Transmembrane protein 184C OS=Rattus norvegicus GN=Tmem184c
PE=2 SV=1
Length = 503
Score = 144 bits (362), Expect = 2e-033
Identities = 84/282 (29%), Positives = 152/282 (53%), Gaps = 15/282 (5%)
Frame = +2
Query: 293 FYCSALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSE 472
++ + + + +T+ +++ + QHL H+ P+ QK I+ I+ M PIY++ S+V L K
Sbjct: 49 WFIAGIFLLLTIPVSMCGILQHLVHYTQPELQKPIIRILWMVPIYSLDSWVALKYPK--- 105
Query: 473 IFFLFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHV 652
+++++ +ECYEA VI F+ + +YL I ++ K ++ +H P+ P
Sbjct: 106 -IAIYVDTWRECYEAYVIYNFMIFLTNYLTIRFPNLMLHLEAKDQQ-NHLPPLCCCPPWA 163
Query: 653 VRLDHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFYPSW-----LSWTFTIVL-NLSV 814
+ L K Q+ V+RP+ ++ + +I+G Y +WT+ ++L NLS
Sbjct: 164 --MGEMLLFRCKLGVLQYTVVRPITTVTSLVCEILGVYDEGNFSFSNAWTYLVILNNLSQ 221
Query: 815 SLALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVI--KSHHF 988
A+Y L++FY V +EL+P P+ KFLC+K +VF FWQ + + +LV +GVI K
Sbjct: 222 LFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVLIALLVKVGVISEKRTWE 281
Query: 989 WLEVEQIQEAIQNVLVCLEMVIFAAVQKHAYHVGPYSGETKK 1114
W E + +Q+ ++C+EM A + + PY E ++
Sbjct: 282 WQSAEAVATGLQDFIICIEMFFAAIAHHYTFSYKPYVHEAEE 323
>sp|Q54PI4|T1841_DICDI Transmembrane protein 184 homolog DDB_G0284525
OS=Dictyostelium discoideum GN=tmem184A PE=3 SV=1
Length = 493
Score = 139 bits (349), Expect = 5e-032
Identities = 90/270 (33%), Positives = 145/270 (53%), Gaps = 19/270 (7%)
Frame = +2
Query: 293 FYCSALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSE 472
F ++L V + +L+ L+ +HL ++ P Q+ I+ IV M PIYA+ S + LL + +
Sbjct: 53 FALASLFVLLATILSAHLIYKHLKYYTQPDHQRYIVRIVFMIPIYAIYSLLSLL-LHNYQ 111
Query: 473 IFFLFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTF-FQPH 649
++F L ++CYEA V+ F AL SY KN+V + P+ F F+P
Sbjct: 112 VYFALL---RDCYEAYVLYMFFALCVSY--GGGDKNLVTHFTSHPVMRLPMPLFFKFKP- 165
Query: 650 VVRLDHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFYP--SWLSWTF----TIVLNLS 811
+ L++ + Q+V++RP ++ +I G Y S+ F ++N+S
Sbjct: 166 ----NEAFLQVCRMGMLQYVLVRPAVTLASAIFEIFGLYDEGSYAINRFYFYNAFIINVS 221
Query: 812 VSLALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVIKSHHFW 991
V++ALY +V+FY A+ELAP+ PL KF IK +VFFCFWQ IA+ + G I + W
Sbjct: 222 VTVALYIVVLFYQAAAEELAPYKPLLKFTSIKIVVFFCFWQSIAISGMTNFGWIPTLDGW 281
Query: 992 LEVEQIQEAIQNVLVCLEMVIFAAVQKHAY 1081
E + +QN L+C EM A + ++A+
Sbjct: 282 NSGE-VSTGLQNFLICFEMFGVAILHQYAF 310
>sp|Q9Y519|T184B_HUMAN Transmembrane protein 184B OS=Homo sapiens GN=TMEM184B
PE=1 SV=2
Length = 407
Score = 136 bits (340), Expect = 6e-031
Identities = 91/285 (31%), Positives = 147/285 (51%), Gaps = 20/285 (7%)
Frame = +2
Query: 302 SALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSEIFF 481
S V+ +L+T + HL + P EQ+ I+ I+ + PIYA S++ LL + ++
Sbjct: 50 SGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQ-YY 108
Query: 482 LFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHVVRL 661
++ ++++CYEALVI FL+L Y YL ++ + I+G+ I S
Sbjct: 109 VYFGTVRDCYEALVIYNFLSLCYEYLG---GESSIMSEIRGKPIESSCMYGTCCLWGKTY 165
Query: 662 DHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFY--------PSWLSWTFTIVLNLSVS 817
LR K T QF V++P+ ++ + LQ G Y +L TI+ N+SVS
Sbjct: 166 SIGFLRFCKQATLQFCVVKPLMAVSTVVLQAFGKYRDGDFDVTSGYL--YVTIIYNISVS 223
Query: 818 LALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVI-KSHHFWL 994
LALY+L +FY + L+P++P+ KF +K ++F FWQG+ L IL G I K H +
Sbjct: 224 LALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSARV 283
Query: 995 EVEQ--IQEAIQNVLVCLEMVIFAAVQKHAYHVGPYSGETKKKLD 1123
V + + Q+ ++C+EM A +HA+ Y K+LD
Sbjct: 284 SVGEGTVAAGYQDFIICVEMFFAALALRHAF---TYKVYADKRLD 325
>sp|A2VDL9|T184B_BOVIN Transmembrane protein 184B OS=Bos taurus GN=TMEM184B PE=2
SV=1
Length = 407
Score = 135 bits (338), Expect = 1e-030
Identities = 88/277 (31%), Positives = 144/277 (51%), Gaps = 17/277 (6%)
Frame = +2
Query: 302 SALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSEIFF 481
S V+ +L+T + HL + P EQ+ I+ I+ + PIYA S++ LL + ++
Sbjct: 50 SGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQ-YY 108
Query: 482 LFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHVVRL 661
++ ++++CYEALVI FL+L Y YL ++ + I+G+ I S
Sbjct: 109 VYFGTVRDCYEALVIYNFLSLCYEYLG---GESSIMSEIRGKPIESSCMYGTCCLWGKTY 165
Query: 662 DHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFY--------PSWLSWTFTIVLNLSVS 817
LR K T QF V++P+ ++ + LQ G Y +L TI+ N+SVS
Sbjct: 166 SIGFLRFCKQATLQFCVVKPLMAVSTVVLQAFGKYRDGDFDVTSGYL--YVTIIYNISVS 223
Query: 818 LALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVI-KSHHFWL 994
LALY+L +FY + L+P++P+ KF +K ++F FWQG+ L IL G I K H +
Sbjct: 224 LALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSARV 283
Query: 995 EVEQ--IQEAIQNVLVCLEMVIFAAVQKHAYHVGPYS 1099
V + + Q+ ++C+EM A +HA+ Y+
Sbjct: 284 SVGEGTVAAGYQDFIICVEMFFAALALRHAFTYKVYA 320
>sp|Q6ZMB5|T184A_HUMAN Transmembrane protein 184A OS=Homo sapiens GN=TMEM184A
PE=2 SV=1
Length = 413
Score = 134 bits (337), Expect = 1e-030
Identities = 89/278 (32%), Positives = 144/278 (51%), Gaps = 18/278 (6%)
Frame = +2
Query: 302 SALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSEIFF 481
S + V+ ++LT + HL + P+EQ+ I+ ++L+ PIYA S++ LL + G ++
Sbjct: 59 SGIFVWTALVLTCHQIYLHLRSYTVPQEQRYIIRLLLIVPIYAFDSWLSLL-LLGDHQYY 117
Query: 482 LFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHVVRL 661
++ +S+++CYEA VI FL+L + YL + + I+G+ I S +
Sbjct: 118 VYFDSVRDCYEAFVIYSFLSLCFQYLG---GEGAIMAEIRGKPIKSSCLYGTCCLRGMTY 174
Query: 662 DHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFY--------PSWLSWTFTIVLNLSVS 817
LR K T QF +++PV ++ I LQ G Y +L T++ N SVS
Sbjct: 175 SIGFLRFCKQATLQFCLVKPVMAVTTIILQAFGKYHDGDFNVRSGYL--YVTLIYNASVS 232
Query: 818 LALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVI----KSHH 985
LALY+L +FY + L P P+ KFL IK ++F FWQG+ L IL GVI S
Sbjct: 233 LALYALFLFYFTTRELLRPFQPVLKFLTIKAVIFLSFWQGLLLAILERCGVIPEVETSGG 292
Query: 986 FWLEVEQIQEAIQNVLVCLEMVIFAAVQKHAYHVGPYS 1099
L + QN ++C+EM+ + ++A+ Y+
Sbjct: 293 NKLGAGTLAAGYQNFIICVEMLFASVALRYAFPCQVYA 330
>sp|Q3UFJ6|T184A_MOUSE Transmembrane protein 184A OS=Mus musculus GN=Tmem184a
PE=2 SV=1
Length = 425
Score = 133 bits (333), Expect = 4e-030
Identities = 92/285 (32%), Positives = 147/285 (51%), Gaps = 32/285 (11%)
Frame = +2
Query: 302 SALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSEIFF 481
S + V+ +LLT + HL + P+EQ+ ++ ++ + PIYA S++ LL + G ++
Sbjct: 62 SGVFVWTALLLTGHQIYSHLRSYTAPREQRFVIRLLFIVPIYAFDSWLSLL-LLGGHPYY 120
Query: 482 LFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHVVR- 658
++ +S+++CYEA VI FL L + YL ++ + I+G+ I S F+ +R
Sbjct: 121 VYFDSVRDCYEAFVIYSFLTLCFQYLG---GESAIMAEIRGKPIRSS---CFYGTCCLRG 174
Query: 659 --LDHRTLRLLKYWTWQFVVIRPVCSILMIALQII-----GFYPSWLSWTF-TIVLNLSV 814
LR K T QF +++PV +++ I LQ G + + + T+V N SV
Sbjct: 175 MSYSITFLRFCKQATLQFCIVKPVMALITIILQAFDKYHDGDFNIHSGYLYVTLVYNASV 234
Query: 815 SLALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVIKSHHFWL 994
SLALY+L +FY L P P+ KFL IK I+F FWQG+ L IL GVI
Sbjct: 235 SLALYALFLFYFATRDLLRPFEPVLKFLTIKAIIFLSFWQGMLLAILERCGVIP------ 288
Query: 995 EVEQIQ----------EAIQNVLVCLEMVIFAAVQKHAYHVGPYS 1099
EV+ + QN L+C+EM+ + ++A+ YS
Sbjct: 289 EVQAVDGTRVGAGTLAAGYQNFLICVEMLFASLALRYAFPSQVYS 333
>sp|Q4QQS1|T184A_RAT Transmembrane protein 184A OS=Rattus norvegicus GN=Tmem184a
PE=2 SV=1
Length = 425
Score = 133 bits (333), Expect = 4e-030
Identities = 92/285 (32%), Positives = 147/285 (51%), Gaps = 32/285 (11%)
Frame = +2
Query: 302 SALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSEIFF 481
S + V+ +LLT + HL + P+EQ+ ++ ++ + PIYA S++ LL + G ++
Sbjct: 62 SGVFVWTALLLTGHQIYSHLRSYTVPREQRFVIRLLFIVPIYAFDSWLSLL-LLGGHPYY 120
Query: 482 LFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHVVR- 658
++ +S+++CYEA VI FL L + YL ++ + I+G+ I S F+ +R
Sbjct: 121 VYFDSVRDCYEAFVIYSFLTLCFQYLG---GESAIMAEIRGKPIRSS---CFYGTCCLRG 174
Query: 659 --LDHRTLRLLKYWTWQFVVIRPVCSILMIALQII-----GFYPSWLSWTF-TIVLNLSV 814
LR K T QF +++PV +++ I LQ G + + + T+V N SV
Sbjct: 175 MSYSITFLRFCKQATLQFCIVKPVMALITIILQAFDKYHDGDFNIHSGYLYVTLVYNASV 234
Query: 815 SLALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVIKSHHFWL 994
SLALY+L +FY L P P+ KFL IK I+F FWQG+ L IL GVI
Sbjct: 235 SLALYALFLFYFATRDLLRPFEPVLKFLTIKAIIFLSFWQGMLLAILERCGVIP------ 288
Query: 995 EVEQIQ----------EAIQNVLVCLEMVIFAAVQKHAYHVGPYS 1099
EV+ + QN L+C+EM+ + ++A+ YS
Sbjct: 289 EVQAVDGTRVGAGTLAAGYQNFLICIEMLFASLALRYAFPSQVYS 333
>sp|Q8BG09|T184B_MOUSE Transmembrane protein 184B OS=Mus musculus GN=Tmem184b
PE=2 SV=1
Length = 407
Score = 132 bits (332), Expect = 5e-030
Identities = 88/285 (30%), Positives = 143/285 (50%), Gaps = 20/285 (7%)
Frame = +2
Query: 302 SALSVFITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIYAVVSFVGLLDVKGSEIFF 481
S V+ +L+T + HL + P EQ+ I+ I+ + PIYA S++ LL + ++
Sbjct: 50 SGFFVWTALLITCHQIYMHLRCYSRPNEQRHIVRILFIVPIYAFDSWLSLLFFTNDQ-YY 108
Query: 482 LFLESIKECYEALVIAKFLALMYSYLNISISKNIVPDGIKGREIHHSFPMTFFQPHVVRL 661
++ ++++CYEA VI FL+L Y YL ++ + I+G+ I S
Sbjct: 109 VYFGTVRDCYEAFVIYNFLSLCYEYLG---GESAIMSEIRGKAIESSCMYGTCCLWGKTY 165
Query: 662 DHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFY--------PSWLSWTFTIVLNLSVS 817
LR K T QF V++P+ ++ + LQ G Y +L TI+ N+SVS
Sbjct: 166 SIGFLRFCKQATLQFCVVKPLMAVSTVILQAFGKYRDGDFDVTSGYL--YVTIIYNISVS 223
Query: 818 LALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGV---IKSHHF 988
LALY+L +FY + L+P++P+ KF +K ++F FWQG+ L IL G I S
Sbjct: 224 LALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKINSARV 283
Query: 989 WLEVEQIQEAIQNVLVCLEMVIFAAVQKHAYHVGPYSGETKKKLD 1123
+ + Q+ ++C+EM A +HA+ Y K+LD
Sbjct: 284 SVGEGTVAAGYQDFIICVEMFFAALALRHAF---TYKVYADKRLD 325
>sp|Q1RMW2|T184A_BOVIN Transmembrane protein 184A OS=Bos taurus GN=TMEM184A PE=2
SV=1
Length = 414
Score = 89 bits (219), Expect = 6e-017
Identities = 54/158 (34%), Positives = 82/158 (51%), Gaps = 14/158 (8%)
Frame = +2
Query: 674 LRLLKYWTWQFVVIRPVCSILMIALQIIGFY--------PSWLSWTFTIVLNLSVSLALY 829
LR K T QF +++P+ +++ I LQ G Y +L T+V N SVSLALY
Sbjct: 169 LRFCKQATLQFCIVKPIMALVTIVLQAFGKYHDGDFNVRSGYL--YITLVYNASVSLALY 226
Query: 830 SLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVIKSHHF----WLE 997
+L +FY + L P P+ KFL IK ++F FWQG+ L IL GVI +
Sbjct: 227 ALFLFYSATRELLQPFEPVLKFLTIKAVIFLSFWQGLLLAILERCGVIPEVQVIDGSTVG 286
Query: 998 VEQIQEAIQNVLVCLEMVIFAAVQKHAYHVGPYSGETK 1111
+ QN ++C+EM+ + ++A+ YS +T+
Sbjct: 287 AGTVAAGYQNFIICIEMLFASIALRYAFTCQVYSEKTE 324
>sp|Q09906|TM184_SCHPO Transmembrane protein 184 homolog C30D11.06c
OS=Schizosaccharomyces pombe GN=SPAC30D11.06c PE=1 SV=1
Length = 426
Score = 79 bits (194), Expect = 5e-014
Identities = 51/170 (30%), Positives = 83/170 (48%), Gaps = 14/170 (8%)
Frame = +2
Query: 623 FPMTFFQPHVVRLDHRTLRLLKYWTWQFVVIRPVCSILMIALQIIGFY-----PSWLS-- 781
+P+ + Q + D T +K Q+ ++P I ++ ++ G Y P + S
Sbjct: 110 WPLNYLQDDIDLSDPYTFLSIKRGILQYTWLKPFLVIAVLLTKVTGVYDREDQPVYASAD 169
Query: 782 -WTFTIVLNLSVSLALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILV 958
W +V N+S++L+LYSL F+ +ELAP P KFL +K I+F +WQ L I
Sbjct: 170 LW-IGLVYNISITLSLYSLTTFWVCLHEELAPFRPFPKFLSVKAIIFASYWQQTVLSITN 228
Query: 959 AMGVIKSHHFWLEVEQIQEAIQNVLVCLEMVIFAAVQKHAYHVGPYSGET 1108
+G++ + + QNVL+CLEM FA +A+ + Y T
Sbjct: 229 WLGLLNGTGWIYSLLN-----QNVLMCLEMPFFALSHWYAFRIEDYDTPT 273
>sp|P36142|TM184_YEAST Transmembrane protein 184 homolog YKR051W
OS=Saccharomyces cerevisiae GN=YKR051W PE=1 SV=1
Length = 418
Score = 64 bits (154), Expect = 2e-009
Identities = 35/102 (34%), Positives = 56/102 (54%), Gaps = 3/102 (2%)
Frame = +2
Query: 794 IVLNLSVSLALYSLVVFYHVFAKELAPHNPLAKFLCIKGIVFFCFWQGIALDILVAMGVI 973
+ N+SV+ +LYSL +F+ EL P+ P KFLC+K I+F +WQ I + LV G +
Sbjct: 173 VFYNISVTWSLYSLALFWKCLYPELTPYKPWLKFLCVKLIIFASYWQSIIIQGLVVTGKL 232
Query: 974 KSHHFWLEVEQIQEAIQNVLVCLEMVIFAAVQKHAYHVGPYS 1099
+ + + +N L+C+EMV FA + A+ Y+
Sbjct: 233 GTGN---QDRTSGYVYKNGLLCIEMVPFAILHAVAFPWNKYT 271
>sp|Q75JN3|T1842_DICDI Transmembrane protein 184 homolog DDB_G0276041
OS=Dictyostelium discoideum GN=tmem184B PE=3 SV=1
Length = 507
Score = 56 bits (134), Expect = 5e-007
Identities = 31/104 (29%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Frame = +2
Query: 263 LTKLKPPQITFYCSALSV-----FITVLLTLQLVSQHLSHWKNPKEQKAILIIVLMAPIY 427
+T + + FY LS+ ++++ + L+ QH H+ P QK I+ I+++APIY
Sbjct: 1 MTTIVEEEPLFYIVMLSIGSFFALGSIIIAVILILQHFIHYNKPNHQKYIVRIIMIAPIY 60
Query: 428 AVVSFVGLLDVKGSEIFFLFLESIKECYEALVIAKFLALMYSYL 559
A+ S + L + + + LF + ++CYEA V+ F L+ +L
Sbjct: 61 AIHSLLSLFFKR--QFWALFFDISRDCYEAYVLYCFFKLLICFL 102
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0
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