BLASTX 7.6.2
Query= UN16983 /QuerySize=1050
(1049 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q94A20|BI1L_ARATH BI1-like protein OS=Arabidopsis thaliana GN... 492 2e-138
sp|Q9DA39|TMBI4_MOUSE Transmembrane BAX inhibitor motif-containi... 146 4e-034
sp|Q9HC24|TMBI4_HUMAN Transmembrane BAX inhibitor motif-containi... 144 9e-034
sp|O74888|YQE4_SCHPO Uncharacterized membrane protein C576.04 OS... 144 9e-034
sp|Q11080|TMBI4_CAEEL Transmembrane BAX inhibitor motif-containi... 122 4e-027
sp|O88407|FAIM2_RAT Fas apoptotic inhibitory molecule 2 OS=Rattu... 85 7e-016
sp|Q9BWQ8|FAIM2_HUMAN Fas apoptotic inhibitory molecule 2 OS=Hom... 66 4e-010
sp|Q5R4I4|FAIM2_PONAB Fas apoptotic inhibitory molecule 2 OS=Pon... 64 2e-009
sp|Q1LZ71|FAIM2_BOVIN Fas apoptotic inhibitory molecule 2 OS=Bos... 62 5e-009
sp|P48558|YN45_YEAST Uncharacterized vacuolar membrane protein Y... 52 8e-006
>sp|Q94A20|BI1L_ARATH BI1-like protein OS=Arabidopsis thaliana GN=At4g15470 PE=2
SV=1
Length = 256
Score = 492 bits (1266), Expect = 2e-138
Identities = 243/256 (94%), Positives = 253/256 (98%)
Frame = -1
Query: 986 MEKPYGYASVSMSGVDRSAGKDIDLEMGGGEATLYPGLSYGENQLRWGFIRKVYGILSAQ 807
M+KPYGYASVSMSG+DRSAGKDIDLEMG GEATLYPGLSYGENQLRWGFIRKVYGILSAQ
Sbjct: 1 MDKPYGYASVSMSGIDRSAGKDIDLEMGVGEATLYPGLSYGENQLRWGFIRKVYGILSAQ 60
Query: 806 LLLTTLISAVVVLNPPVNDLLTGSPGLLLFLCIIPFVLIWPLHVYHQKHPVNLILLALFT 627
LLLTTLISAVVVLNPPVNDLLTGSPG+LLFLCI+PF+LIWPLH+YHQKHPVNLILLALFT
Sbjct: 61 LLLTTLISAVVVLNPPVNDLLTGSPGILLFLCIVPFILIWPLHIYHQKHPVNLILLALFT 120
Query: 626 ISLSFTVGVSCAMTEGRIVLEALILTFSVVGSLTAYTFWAAKKGKDFSFLGPILFTSLII 447
+SLSFTVGVSCAMTEGRIVL+ALILT SVVGSLTAYTFWAAKKGKDFSFLGPILFTSLII
Sbjct: 121 VSLSFTVGVSCAMTEGRIVLQALILTLSVVGSLTAYTFWAAKKGKDFSFLGPILFTSLII 180
Query: 446 LVVTSFMQMFFPLGPTSVAIYGGISALVFCGYIVYDTDNLIKRFTYDEYILASVALYLDI 267
LVVTSF+QMFFPLGPTSVA+YGG SALVFCGYIVYDTDNLIKRFTYDEYILASVALYLDI
Sbjct: 181 LVVTSFIQMFFPLGPTSVAVYGGFSALVFCGYIVYDTDNLIKRFTYDEYILASVALYLDI 240
Query: 266 LNLFLTILRILRQGDN 219
LNLFLTILRILRQGDN
Sbjct: 241 LNLFLTILRILRQGDN 256
>sp|Q9DA39|TMBI4_MOUSE Transmembrane BAX inhibitor motif-containing protein 4
OS=Mus musculus GN=Tmbim4 PE=2 SV=1
Length = 238
Score = 146 bits (366), Expect = 4e-034
Identities = 80/207 (38%), Positives = 126/207 (60%), Gaps = 4/207 (1%)
Frame = -1
Query: 854 LRWGFIRKVYGILSAQLLLTTLISAVVVLNPPVNDLLTGSPGLLLFLCIIPFVLIWPLHV 675
+R F+RKVY ILS Q+LLTT+ SA+ + + + SP L++ + LI+ L +
Sbjct: 30 IRMAFLRKVYSILSLQVLLTTVTSALFLYFQALRTFVHESPALIVVFALGSLGLIFALTL 89
Query: 674 YHQKHPVNLILLALFTISLSFTVGVSCAMTEGRIVLEALILTFSVVGSLTAYTFWAAKKG 495
+ HP+NL LL FT+S S V + +VL+A I+T +V LTAYT +
Sbjct: 90 HRHTHPLNLYLLFAFTLSESLAVAAVVTFYDVYLVLQAFIMTTAVFLGLTAYTL---QSK 146
Query: 494 KDFSFLGPILFTSLIILVVTSFMQMFFPLGPTSVAIYGGISALVFCGYIVYDTDNLIKRF 315
+DF+ G LF L IL + F+++FF T + + AL+FCG+I+YDT +L+ R
Sbjct: 147 RDFTKFGAGLFAGLWILCLAGFLKLFF-YSETMELVLASLGALLFCGFIIYDTHSLMHRL 205
Query: 314 TYDEYILASVALYLDILNLFLTILRIL 234
+ +EY++A+++LY+DI+NLFL +L+ L
Sbjct: 206 SPEEYVIAAISLYMDIINLFLHLLKFL 232
>sp|Q9HC24|TMBI4_HUMAN Transmembrane BAX inhibitor motif-containing protein 4
OS=Homo sapiens GN=TMBIM4 PE=1 SV=2
Length = 238
Score = 144 bits (363), Expect = 9e-034
Identities = 85/207 (41%), Positives = 123/207 (59%), Gaps = 4/207 (1%)
Frame = -1
Query: 854 LRWGFIRKVYGILSAQLLLTTLISAVVVLNPPVNDLLTGSPGLLLFLCIIPFVLIWPLHV 675
+R F+RKVY ILS Q+LLTT+ S V + V + SP L+L + LI+ L +
Sbjct: 30 IRMAFLRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHESPALILLFALGSLGLIFALTL 89
Query: 674 YHQKHPVNLILLALFTISLSFTVGVSCAMTEGRIVLEALILTFSVVGSLTAYTFWAAKKG 495
K+P+NL LL FT+ + TV V + I+L+A ILT +V LT YT +
Sbjct: 90 NRHKYPLNLYLLFGFTLLEALTVAVVVTFYDVYIILQAFILTTTVFFGLTVYTL---QSK 146
Query: 494 KDFSFLGPILFTSLIILVVTSFMQMFFPLGPTSVAIYGGISALVFCGYIVYDTDNLIKRF 315
KDFS G LF L IL ++ F++ FF + AL+FCG+I+YDT +L+ +
Sbjct: 147 KDFSKFGAGLFALLWILCLSGFLKFFF-YSEIMELVLAAAGALLFCGFIIYDTHSLMHKL 205
Query: 314 TYDEYILASVALYLDILNLFLTILRIL 234
+ +EY+LA+++LYLDI+NLFL +LR L
Sbjct: 206 SPEEYVLAAISLYLDIINLFLHLLRFL 232
>sp|O74888|YQE4_SCHPO Uncharacterized membrane protein C576.04
OS=Schizosaccharomyces pombe GN=SPCC576.04 PE=2 SV=1
Length = 266
Score = 144 bits (363), Expect = 9e-034
Identities = 80/207 (38%), Positives = 122/207 (58%), Gaps = 3/207 (1%)
Frame = -1
Query: 854 LRWGFIRKVYGILSAQLLLTTLISAVVVLNPPVNDLLTGSPGLLLFLCIIPFVLIWPLHV 675
+R F+RKVY IL+AQL +T+L + L+P + + P L+ I V+++ L +
Sbjct: 54 IRMAFLRKVYAILTAQLFVTSLFGGIFYLHPAFSFWVQMHPWFLILNFFISLVVLFGLIM 113
Query: 674 YHQKHPVNLILLALFTISLSFTVGVSCAMTEGRIVLEALILTFSVVGSLTAYTFWAAKKG 495
+P N I L LFT T+G + RI+LEA+ +T V +LTA+TF +
Sbjct: 114 KPYSYPRNYIFLFLFTALEGLTLGTAITFFSARIILEAVFITLGVFVALTAFTF---QSK 170
Query: 494 KDFSFLGPILFTSLIILVVTSFMQMFFPLGPTSVAIYGGISALVFCGYIVYDTDNLIKRF 315
DFS LG L+ SL L++T + F P P + G LVFCGYI++DT N++ R+
Sbjct: 171 WDFSRLGGFLYVSLWSLILTPLIFFFVPSTPFIDMAFAGFGTLVFCGYILFDTYNILHRY 230
Query: 314 TYDEYILASVALYLDILNLFLTILRIL 234
+ +E+I++S+ LYLD +NLF+ IL+IL
Sbjct: 231 SPEEFIMSSLMLYLDFINLFIRILQIL 257
>sp|Q11080|TMBI4_CAEEL Transmembrane BAX inhibitor motif-containing protein 4
OS=Caenorhabditis elegans GN=tmbi-4 PE=2 SV=2
Length = 276
Score = 122 bits (306), Expect = 4e-027
Identities = 80/223 (35%), Positives = 122/223 (54%), Gaps = 5/223 (2%)
Frame = -1
Query: 887 LYPG-LSYGENQLRWGFIRKVYGILSAQLLLTTLISAVVVLNPPVNDLLTGSPGLLLFLC 711
+ PG + +R F+RKV GI+ QLL T I A + P N LL ++
Sbjct: 57 ILPGCVGKANRMIRIAFLRKVLGIVGFQLLFTIGICAAIYNIPNSNQLLQKHAWIVFPNL 116
Query: 710 IIPFVLIWPLHVYHQKHPVNLILLALFTISLSFTVGVSCAMTEGRIVLEALILTFSVVGS 531
+ LI LHVY ++ P+N +LLA FT + T+G + E ++VLEA ++T VV S
Sbjct: 117 LGSIALIIALHVYAREVPLNYVLLAAFTAVQAVTMGCVVTLFEAKVVLEAAVITGLVVAS 176
Query: 530 LTAYTFWAAKKGKDFSFLGPILFTSLIILVVTSFMQMFFPLGPTSVAIYGGISALVFCGY 351
L AYT + +DFS + + L +L+ QMFF + P + A +FC
Sbjct: 177 LFAYTL---QNKRDFSVGYASMGSLLCVLLWAGIFQMFF-MSPAVNFVINVFGAGLFCVL 232
Query: 350 IVYDTDNLIKRFTYDEYILASVALYLDILNLFLTILRILRQGD 222
+V D D ++ RF+ ++YI A V+LY+DILNLF+ IL+I+ + +
Sbjct: 233 LVIDLDMIMYRFSPEDYICACVSLYMDILNLFIRILQIVAEAN 275
>sp|O88407|FAIM2_RAT Fas apoptotic inhibitory molecule 2 OS=Rattus norvegicus
GN=Faim2 PE=2 SV=1
Length = 316
Score = 85 bits (209), Expect = 7e-016
Identities = 74/269 (27%), Positives = 126/269 (46%), Gaps = 21/269 (7%)
Frame = -1
Query: 995 LRAMEKPYGYASV----SMSGVDRSAGKDIDLEMGGGEATLYPGLSYGENQLRWGFIRKV 828
L+A P G +V S + VD S+ + G L+ S+ + ++R FIRKV
Sbjct: 47 LKAGAFPQGPTAVPLHPSWAYVDPSSSSGYEGGFPAGHHELFSTFSWDDQKVRQLFIRKV 106
Query: 827 YGILSAQLLLTTLISAVVVLNPPVNDLLTGSPGLLLFLCIIPFVLIWPLHVY---HQKHP 657
Y IL QLL+T + A+ V D + +PG + F L + P
Sbjct: 107 YTILLVQLLVTLAVVALFTFCDVVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFP 166
Query: 656 VNLILLALFTISLSFTVGVSCAMTEGRIVLEALILTFSVVGSLTAYTF-----WAAKKGK 492
NLILL +FT+S+++ G+ + VL L +T V S+T ++F + + G
Sbjct: 167 WNLILLTIFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTIFSFQTKFDFTSCHGV 226
Query: 491 DFSFLGPILFTSLIILVVTSFMQMFFPLGPTSVAIYGGISALVFCGYIVYDTDNLI---- 324
F L + F+ L++ ++ F + P A+Y + A VF ++ +DT L+
Sbjct: 227 LFVLLMTLFFSGLLLAILLPFQYV-----PWLHAVYAVLGAGVFTLFLAFDTQLLMGNRR 281
Query: 323 KRFTYDEYILASVALYLDILNLFLTILRI 237
+ +EYI ++ +YLDI+ +F L++
Sbjct: 282 HSLSPEEYIFGALNIYLDIIYIFTFFLQL 310
>sp|Q9BWQ8|FAIM2_HUMAN Fas apoptotic inhibitory molecule 2 OS=Homo sapiens
GN=FAIM2 PE=1 SV=1
Length = 316
Score = 66 bits (159), Expect = 4e-010
Identities = 52/174 (29%), Positives = 83/174 (47%), Gaps = 6/174 (3%)
Frame = -1
Query: 956 SMSGVDRSAGKDIDLEMGGGEATLYPGLSYGENQLRWGFIRKVYGILSAQLLLTTLISAV 777
S + VD S+ D G+ L+ S+ + ++R F+RKVY IL QLL+T + A+
Sbjct: 64 SWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAVVAL 123
Query: 776 VVLNPPVNDLLTGSPGLLLFLCIIPFVLIWPLHVY---HQKHPVNLILLALFTISLSFTV 606
PV D + +PG + F L + P NLILL +FT+S+++
Sbjct: 124 FTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMAYLT 183
Query: 605 GVSCAMTEGRIVLEALILTFSVVGSLTAYTFWAAKKGKDFSFLGPILFTSLIIL 444
G+ + VL L +T V S+T ++F + DF+ +LF L+ L
Sbjct: 184 GMLSSYYNTTSVLLCLGITALVCLSVTVFSF---QTKFDFTSCQGVLFVLLMTL 234
>sp|Q5R4I4|FAIM2_PONAB Fas apoptotic inhibitory molecule 2 OS=Pongo abelii
GN=FAIM2 PE=2 SV=1
Length = 316
Score = 64 bits (153), Expect = 2e-009
Identities = 46/151 (30%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Frame = -1
Query: 956 SMSGVDRSAGKDIDLEMGGGEATLYPGLSYGENQLRWGFIRKVYGILSAQLLLTTLISAV 777
S + VD S+ D G+ L+ S+ + ++R F+RKVY IL QLL+T + A+
Sbjct: 64 SWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAVVAL 123
Query: 776 VVLNPPVNDLLTGSPGLLLFLCIIPFVLIWPLHVY---HQKHPVNLILLALFTISLSFTV 606
PV D + +PG + F L + P NLILL +FT+S+++
Sbjct: 124 FTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMAYLT 183
Query: 605 GVSCAMTEGRIVLEALILTFSVVGSLTAYTF 513
G+ + VL L +T V S+T ++F
Sbjct: 184 GMLSSYYNTTSVLLCLGITALVCLSVTVFSF 214
>sp|Q1LZ71|FAIM2_BOVIN Fas apoptotic inhibitory molecule 2 OS=Bos taurus
GN=FAIM2 PE=2 SV=1
Length = 316
Score = 62 bits (150), Expect = 5e-009
Identities = 50/174 (28%), Positives = 82/174 (47%), Gaps = 6/174 (3%)
Frame = -1
Query: 956 SMSGVDRSAGKDIDLEMGGGEATLYPGLSYGENQLRWGFIRKVYGILSAQLLLTTLISAV 777
S + VD ++ + G+ + S+ + ++R FIRKVY IL QLL+T + A+
Sbjct: 64 SWAYVDPNSSSSYESGFPTGDHEFFTTFSWDDQKVRRVFIRKVYTILLIQLLVTLGVVAL 123
Query: 776 VVLNPPVNDLLTGSPGLLLFLCIIPFVLIWPLHVY---HQKHPVNLILLALFTISLSFTV 606
PV D + +PG + F L + P NLILL +FT+S+++
Sbjct: 124 FTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTIFTLSMAYLT 183
Query: 605 GVSCAMTEGRIVLEALILTFSVVGSLTAYTFWAAKKGKDFSFLGPILFTSLIIL 444
G+ + VL L +T V S+T ++F + DF+ +LF L+ L
Sbjct: 184 GMLSSYYNTTSVLLCLSITALVCLSVTVFSF---QTKFDFTSCQGVLFVLLMTL 234
>sp|P48558|YN45_YEAST Uncharacterized vacuolar membrane protein YNL305C
OS=Saccharomyces cerevisiae GN=YNL305C PE=1 SV=1
Length = 297
Score = 52 bits (122), Expect = 8e-006
Identities = 23/57 (40%), Positives = 38/57 (66%)
Frame = -1
Query: 389 IYGGISALVFCGYIVYDTDNLIKRFTYDEYILASVALYLDILNLFLTILRILRQGDN 219
+YG + A++F Y+ DT + ++ DE + ++ LYLDI+NLFL+ILRIL ++
Sbjct: 239 LYGWLGAILFTAYLFIDTQLIFRKVYPDEEVRCAMMLYLDIVNLFLSILRILANSND 295
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0
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