BLASTX 7.6.2
Query= UN16989 /QuerySize=1989
(1988 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9W0I6|SAC1_DROME Phosphatidylinositide phosphatase SAC1 OS=D... 339 8e-092
sp|A6QL88|SAC1_BOVIN Phosphatidylinositide phosphatase SAC1 OS=B... 337 2e-091
sp|Q6GM29|SAC1_XENLA Phosphatidylinositide phosphatase SAC1 OS=X... 335 6e-091
sp|Q9ES21|SAC1_RAT Phosphatidylinositide phosphatase SAC1 OS=Rat... 333 4e-090
sp|Q5R921|SAC1_PONAB Phosphatidylinositide phosphatase SAC1 OS=P... 330 2e-089
sp|A4VCH0|SAC1B_DANRE Phosphatidylinositide phosphatase SAC1-B O... 330 3e-089
sp|Q9NTJ5|SAC1_HUMAN Phosphatidylinositide phosphatase SAC1 OS=H... 330 3e-089
sp|A1L244|SAC1A_DANRE Phosphatidylinositide phosphatase SAC1-A O... 328 1e-088
sp|Q9EP69|SAC1_MOUSE Phosphatidylinositide phosphatase SAC1 OS=M... 327 2e-088
sp|Q55AW9|SAC1_DICDI Phosphatidylinositide phosphatase SAC1 OS=D... 288 2e-076
sp|O14127|YF51_SCHPO Uncharacterized protein C3C7.01c OS=Schizos... 238 1e-061
sp|A8E7C5|SAC2_DANRE Phosphatidylinositide phosphatase SAC2 OS=D... 218 2e-055
sp|Q8CDA1|SAC2_MOUSE Phosphatidylinositide phosphatase SAC2 OS=M... 209 9e-053
sp|Q9Y2H2|SAC2_HUMAN Phosphatidylinositide phosphatase SAC2 OS=H... 207 3e-052
>sp|Q9W0I6|SAC1_DROME Phosphatidylinositide phosphatase SAC1 OS=Drosophila
melanogaster GN=Sac1 PE=1 SV=1
Length = 592
Score = 339 bits (867), Expect = 8e-092
Identities = 219/591 (37%), Positives = 323/591 (54%), Gaps = 33/591 (5%)
Frame = -3
Query: 1887 LYDHLQLLEFPDKYVIKPVDSPHEGFSVDRRD--GNIKPLDDNTSSVNATKVSTIFGVGG 1714
+YD + L P ++I+P + E + R D ++P + N I GV G
Sbjct: 9 VYDDMNLYIAPQSFIIEP-NGGDELLVIGRHDKVTRVQPASGGLVA-NLRPTRRICGVLG 66
Query: 1713 TIRLLAGTYLLVITSREEAGTFLGFPIFRVTAMKFLPCNANLRFATAQERRDEAYFRTLL 1534
TI LL+ YLLV T R G G ++R+ +P N + Q + +E Y R L
Sbjct: 67 TIHLLSCDYLLVATHRLFVGVLNGAVVWRLAGYDIIPYIPN----SFQRKENENYLRLLR 122
Query: 1533 QALETTPGLYFSYETDLTVNLQRRCKLAVGWTSKP----MWKQADPRYVWNWHLLEELIE 1366
Q L+ T YFSY DLT +LQR+ ++A S+P + ++A+ R+VWN ++L +
Sbjct: 123 QTLD-TKFFYFSYRYDLTNSLQRQREVA---QSRPEVSGLLQRAEQRFVWNGYVLRQFNC 178
Query: 1365 CKLDGFITPLLQGSYQVAELQLKNSPSVISLISRRCTRRLGTRMWRRGANLEGDTANFVE 1186
K++ F PL+ G + ++Q+ S+I+RR +R GTR++ RG++ +G ANFVE
Sbjct: 179 DKMEKFQLPLVLGFVSINQVQINGQTFFWSIITRRSVQRAGTRLFCRGSDEQGHVANFVE 238
Query: 1185 SEQIMEINGFKFSLLQVRGSIPLLWEQIVDLSYKPQLKINKHEDTPKVVQRHFHDLSQRY 1006
+EQI+E NG +Q RGS+P W Q+ +L YKP+ + +D HF + + Y
Sbjct: 239 TEQIVEFNGQLTGFVQTRGSMPFHWHQLPNLRYKPRPVLVPGKDHLAACGLHFKEQIRLY 298
Query: 1005 GEIMVVNLTDQDGAEGELGKAYATEMARL--PNVRFVAFDFHHICGTTNFDNLGVLYEEI 832
G + VNL D GAEGEL YA + + P VR+ +FDFH C +D L +L + +
Sbjct: 299 GNNVAVNLVDHKGAEGELEATYARLVREMGNPQVRYESFDFHSECRKMRWDRLNILIDRL 358
Query: 831 GDEFEKQGYFLVDADGNILEEQKGVVRSNCIDCLDRTNVTQNYMAQKSLNLQLQRIGVLD 652
E ++ G + V DG ++ Q GV R+NCIDCLDRTNV Q+ +A++SL LQ++GVL
Sbjct: 359 AHEQDQFGVYHVFDDGKLVSTQTGVFRTNCIDCLDRTNVVQSMLARRSLTAVLQKLGVLH 418
Query: 651 SKECVSMFGDDYTK-FRTIWAEQGDEISLQYAGTYALKGDLVRYGKQTVSGAIKDGISAM 475
+ V D + F+ +WA+ D +SLQY+GT ALK D R GK+T SGA++DG +++
Sbjct: 419 VGQKVEHASDIFESIFKGVWADNADLVSLQYSGTCALKTDFTRTGKRTKSGAMQDGKNSL 478
Query: 474 SRYYLNNFQDGVRQDALDLISGRYTVGTNS----PSQLQPIGG----SQPSFLPVASALL 319
RYYLNNF DG RQD++DL G+Y V N PS L+ G + PS L VA A+
Sbjct: 479 MRYYLNNFADGQRQDSIDLFLGKYLVNDNEGGAVPSPLESKHGWRFFTFPSVLLVAVAMF 538
Query: 318 IGGVTVTSFTFHQAGRNTQQYLASALWAGVTAGVVAMIKVNGRHLCSRPRL 166
+ +T+T + A NT+ L W + A I G PRL
Sbjct: 539 M--ITMT----YPAEFNTENLLFMLFWGAMIAVSATGILHYGVEFVQWPRL 583
>sp|A6QL88|SAC1_BOVIN Phosphatidylinositide phosphatase SAC1 OS=Bos taurus
GN=SACM1L PE=2 SV=1
Length = 587
Score = 337 bits (863), Expect = 2e-091
Identities = 208/578 (35%), Positives = 308/578 (53%), Gaps = 8/578 (1%)
Frame = -3
Query: 1884 YDHLQLLEFPDKYVIKPVDSPHEGFSVDRRDGNIKPLDDNTSSVNATKVSTIFGVGGTIR 1705
Y+ L+L P+K+ ++ D + + R L + IFG+ GTI
Sbjct: 6 YERLKLHVTPEKFYVEACDDGADDVLIIDRVSTEVTLSVKKDIPPSAVTRPIFGILGTIH 65
Query: 1704 LLAGTYLLVITSREEAGTFLGFPIFRVTAMKFLPCNANLRFATAQERRDEAYFRTLLQAL 1525
L+AG YL+VIT +++ G F I++ T L + T + +D F ++ +
Sbjct: 66 LVAGNYLIVITKKKKIGEFFNHVIWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMMNHV 125
Query: 1524 ETTPGLYFSYETDLTVNLQRRCKLAVGWTSKPMWKQADPRYVWNWHLLEEL-IECKLDGF 1348
+ G YFS DLT LQR + + + ++AD R+VWN HLL EL + ++ F
Sbjct: 126 LSMDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRF 185
Query: 1347 ITPLLQGSYQVAELQLKNSPSVISLISRRCTRRLGTRMWRRGANLEGDTANFVESEQIME 1168
P+L G + + LISRR R G R + RG + EG ANFVE+EQI+
Sbjct: 186 ALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVH 245
Query: 1167 INGFKFSLLQVRGSIPLLWEQIVDLSYKPQLKINKHEDTPKVVQRHFHDLSQRYGEIMVV 988
NG + S +Q RGSIPL W Q +L YKP INK + QRHF YG+ +++
Sbjct: 246 YNGSRASFVQTRGSIPLYWSQRPNLKYKPLPLINKVANHMDGFQRHFDSQIIIYGKQVII 305
Query: 987 NLTDQDGAEGELGKAYATEMARLPN--VRFVAFDFHHICGTTNFDNLGVLYEEIGDEFEK 814
NL +Q G+E L +A+AT ++ L N +R++AFDFH C +D L +L +++ + ++
Sbjct: 306 NLVNQKGSEKPLEQAFATMVSSLGNGMIRYIAFDFHKECKNMRWDRLSILLDQVAEMQDE 365
Query: 813 QGYFLVDADGNILEEQKGVVRSNCIDCLDRTNVTQNYMAQKSLNLQLQRIGVLDSKECVS 634
YFLVD G +L Q+GV RSNC+DCLDRTNV Q+ +A++SL QLQR+GVL + +
Sbjct: 366 LSYFLVDPAGVVLSTQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLE 425
Query: 633 MFGDDYTKFRTIWAEQGDEISLQYAGTYALKGDLVRYGKQTVSGAIKDGISAMSRYYLNN 454
+ ++ WA+ + + QYAGT ALK D R GK+T G I DG +++ RYY NN
Sbjct: 426 EQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLIMDGWNSLIRYYKNN 485
Query: 453 FQDGVRQDALDLISGRYTVG-TNSPSQLQPIGGSQPSFLPVASALLIGGVTVTSFTFHQA 277
F DG RQD++DL G Y+V S S L + LP+ +++ ++ A
Sbjct: 486 FSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDLKFLALPI---IMVVAFSMCIICLLMA 542
Query: 276 GRNTQQYLASALWAGVTA-GVVAMIKVNGRHLCSRPRL 166
G + LA L+ GV + G +I NG+ PRL
Sbjct: 543 GDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRL 580
>sp|Q6GM29|SAC1_XENLA Phosphatidylinositide phosphatase SAC1 OS=Xenopus laevis
GN=sacm1l PE=2 SV=1
Length = 586
Score = 335 bits (859), Expect = 6e-091
Identities = 203/580 (35%), Positives = 309/580 (53%), Gaps = 12/580 (2%)
Frame = -3
Query: 1884 YDHLQLLEFPDKYVIKPVDSPHEGFSVDRRDGNIKPLDDNTSSVNATKVSTIFGVGGTIR 1705
Y++L+L P+K+ ++ D E R L + I+G+ GTIR
Sbjct: 5 YENLKLHITPEKFYVEACDPGVEDVLTIDRVSTEVTLSGKKDIPPSAITRAIYGILGTIR 64
Query: 1704 LLAGTYLLVITSREEAGTFLGFPIFRVTAMKFLPCNANLRFATAQERRDEAYFRTLLQAL 1525
L+AG YL+VIT R++ G L I++ T + + T + +D F +L +
Sbjct: 65 LVAGMYLIVITRRKKVGDLLNHSIWKATDFDIISYKKTMLHLTDSQLQDNKAFLGMLSHV 124
Query: 1524 ETTPGLYFSYETDLTVNLQRRCKLAVGWTSKPMWKQADPRYVWNWHLLEEL-IECKLDGF 1348
+ G YFS DLT LQR + + + ++AD R+VWN +LL E + ++ F
Sbjct: 125 LSVDGFYFSVSYDLTHTLQRLANTSPEFQEMSLLERADQRFVWNGNLLREFSAQPEIQKF 184
Query: 1347 ITPLLQGSYQVAELQLKNSPSVISLISRRCTRRLGTRMWRRGANLEGDTANFVESEQIME 1168
P++ G + + LISRR R G R + RG + EG ANFVE+EQI+
Sbjct: 185 AIPVVHGFIAIHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVH 244
Query: 1167 INGFKFSLLQVRGSIPLLWEQIVDLSYKPQLKINKHEDTPKVVQRHFHDLSQRYGEIMVV 988
NG K S +Q RGSIP W Q +L YKP+ +I+K + QRHF YG+ +V+
Sbjct: 245 YNGNKASFVQTRGSIPFYWSQRPNLKYKPKPQISKAVNHMDGFQRHFDSQVISYGKQVVL 304
Query: 987 NLTDQDGAEGELGKAYATEMARLPN--VRFVAFDFHHICGTTNFDNLGVLYEEIGDEFEK 814
NL +Q G+E L + ++ ++ L N VR++AFDFH C +D L +L E++ + ++
Sbjct: 305 NLVNQKGSEKPLEQEFSQMVSGLGNGMVRYIAFDFHKECSRMRWDRLQILVEQVAETQDE 364
Query: 813 QGYFLVDADGNILEEQKGVVRSNCIDCLDRTNVTQNYMAQKSLNLQLQRIGVLDSKECVS 634
GYFLVD +G ++ +Q G+ RSNC+DCLDRTNV Q+ +A++SL QLQR+GVL + +
Sbjct: 365 FGYFLVDTEGKVVSQQDGIFRSNCMDCLDRTNVVQSLLARRSLQYQLQRLGVLHVGQRIE 424
Query: 633 MFGDDYTKFRTIWAEQGDEISLQYAGTYALKGDLVRYGKQTVSGAIKDGISAMSRYYLNN 454
++ WA+ + + QYAGT ALK D R GK+T G + DG +++ RYY NN
Sbjct: 425 EQIQFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQWGLLMDGWNSLIRYYKNN 484
Query: 453 FQDGVRQDALDLISGRYTVG---TNSPSQLQPIGGSQPSFLPVASALLIGGVTVTSFTFH 283
F DG RQD++DL G Y+V + SP +Q + FL + +++ ++
Sbjct: 485 FSDGFRQDSIDLFLGNYSVEEAYSTSPLHIQ----TDWKFLAL-PIIMVVAFSMCIICLL 539
Query: 282 QAGRNTQQYLASAL-WAGVTAGVVAMIKVNGRHLCSRPRL 166
AG + LA L W + G A+I NG+ P+L
Sbjct: 540 MAGDTWTETLAYVLFWGTASIGTGAIIMYNGKDFVDAPKL 579
>sp|Q9ES21|SAC1_RAT Phosphatidylinositide phosphatase SAC1 OS=Rattus norvegicus
GN=Sacm1l PE=1 SV=1
Length = 587
Score = 333 bits (852), Expect = 4e-090
Identities = 202/578 (34%), Positives = 309/578 (53%), Gaps = 8/578 (1%)
Frame = -3
Query: 1884 YDHLQLLEFPDKYVIKPVDSPHEGFSVDRRDGNIKPLDDNTSSVNATKVSTIFGVGGTIR 1705
Y+HL+L P+K+ ++ D + + R L + I+G+ GTI
Sbjct: 6 YEHLKLHITPEKFYVEACDDGADDVLIIDRVSTEVTLAVKKDVPPSAVTRPIYGIMGTIH 65
Query: 1704 LLAGTYLLVITSREEAGTFLGFPIFRVTAMKFLPCNANLRFATAQERRDEAYFRTLLQAL 1525
L+AG YL+VIT + + G F I++ T L + T + +D F +L +
Sbjct: 66 LVAGNYLVVITKKMKVGEFFNHVIWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHV 125
Query: 1524 ETTPGLYFSYETDLTVNLQRRCKLAVGWTSKPMWKQADPRYVWNWHLLEEL-IECKLDGF 1348
+T G YFS DLT LQR + + + ++AD R+VWN HLL EL + ++ F
Sbjct: 126 LSTDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRF 185
Query: 1347 ITPLLQGSYQVAELQLKNSPSVISLISRRCTRRLGTRMWRRGANLEGDTANFVESEQIME 1168
P+L G + + LISRR R G R + RG + EG ANFVE+EQI+
Sbjct: 186 ALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVH 245
Query: 1167 INGFKFSLLQVRGSIPLLWEQIVDLSYKPQLKINKHEDTPKVVQRHFHDLSQRYGEIMVV 988
+G + S +Q RGSIP+ W Q +L YKP +INK + QRHF YG+ +++
Sbjct: 246 YSGNRASFVQTRGSIPVFWSQRPNLKYKPDPQINKVANHMDGFQRHFDSQVIIYGKQVII 305
Query: 987 NLTDQDGAEGELGKAYATEMARLPN--VRFVAFDFHHICGTTNFDNLGVLYEEIGDEFEK 814
NL + G+E L + +A ++ L + +R++AFDFH C +D L +L +++ + ++
Sbjct: 306 NLVNHKGSEKPLEQTFAKMVSSLGSGMIRYIAFDFHKECKNMRWDRLSILLDQVAEMQDE 365
Query: 813 QGYFLVDADGNILEEQKGVVRSNCIDCLDRTNVTQNYMAQKSLNLQLQRIGVLDSKECVS 634
YFLVD+ G ++ Q+GV RSNC+DCLDRTNV Q+ +A++SL QLQR+GVL + +
Sbjct: 366 LSYFLVDSAGKVVTNQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLE 425
Query: 633 MFGDDYTKFRTIWAEQGDEISLQYAGTYALKGDLVRYGKQTVSGAIKDGISAMSRYYLNN 454
+ ++ WA+ + + QYAGT ALK D R GK+T G + DG +++ RYY NN
Sbjct: 426 EQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLVMDGFNSLLRYYKNN 485
Query: 453 FQDGVRQDALDLISGRYTVG-TNSPSQLQPIGGSQPSFLPVASALLIGGVTVTSFTFHQA 277
F DG RQD++DL G Y+V +S S L + LP+ +++ ++ A
Sbjct: 486 FSDGFRQDSIDLFLGNYSVDELDSHSPLSVPRDWKFLALPI---IMVVAFSMCIICLLMA 542
Query: 276 GRNTQQYLASALWAGVTA-GVVAMIKVNGRHLCSRPRL 166
G + LA L+ GV + G +I NG+ PRL
Sbjct: 543 GDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRL 580
>sp|Q5R921|SAC1_PONAB Phosphatidylinositide phosphatase SAC1 OS=Pongo abelii
GN=SACM1L PE=2 SV=1
Length = 587
Score = 330 bits (846), Expect = 2e-089
Identities = 206/578 (35%), Positives = 306/578 (52%), Gaps = 8/578 (1%)
Frame = -3
Query: 1884 YDHLQLLEFPDKYVIKPVDSPHEGFSVDRRDGNIKPLDDNTSSVNATKVSTIFGVGGTIR 1705
Y+ L+L P+K+ ++ D + R L + IFG+ GTI
Sbjct: 6 YEQLKLHITPEKFYVEACDDGADDVLTIDRVSTEVTLAVKKDVPPSAVTRPIFGILGTIH 65
Query: 1704 LLAGTYLLVITSREEAGTFLGFPIFRVTAMKFLPCNANLRFATAQERRDEAYFRTLLQAL 1525
L+AG YL+VIT + + G F I++ T L + T + +D F +L +
Sbjct: 66 LVAGNYLIVITKKIKVGEFFSHVIWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHV 125
Query: 1524 ETTPGLYFSYETDLTVNLQRRCKLAVGWTSKPMWKQADPRYVWNWHLLEEL-IECKLDGF 1348
G YFS DLT LQR + + + ++AD R+VWN HLL EL + ++ F
Sbjct: 126 LNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRF 185
Query: 1347 ITPLLQGSYQVAELQLKNSPSVISLISRRCTRRLGTRMWRRGANLEGDTANFVESEQIME 1168
P+L G + + LISRR R G R + RG + EG ANFVE+EQI+
Sbjct: 186 ALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVH 245
Query: 1167 INGFKFSLLQVRGSIPLLWEQIVDLSYKPQLKINKHEDTPKVVQRHFHDLSQRYGEIMVV 988
NG K S +Q RGSIP+ W Q +L YKP +I+K + QRHF YG+ +++
Sbjct: 246 YNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVII 305
Query: 987 NLTDQDGAEGELGKAYATEMARLPN--VRFVAFDFHHICGTTNFDNLGVLYEEIGDEFEK 814
NL +Q G+E L + +AT ++ L + +R++AFDFH C +D L +L +++ + ++
Sbjct: 306 NLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDE 365
Query: 813 QGYFLVDADGNILEEQKGVVRSNCIDCLDRTNVTQNYMAQKSLNLQLQRIGVLDSKECVS 634
YFLVD+ G ++ Q+GV RSNC+DCLDRTNV Q+ +A++SL QLQR+GVL + +
Sbjct: 366 LSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLE 425
Query: 633 MFGDDYTKFRTIWAEQGDEISLQYAGTYALKGDLVRYGKQTVSGAIKDGISAMSRYYLNN 454
+ ++ WA+ + + QYAGT ALK D R GK+T G I DG ++M RYY NN
Sbjct: 426 EQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNN 485
Query: 453 FQDGVRQDALDLISGRYTVG-TNSPSQLQPIGGSQPSFLPVASALLIGGVTVTSFTFHQA 277
F DG RQD++DL G Y+V S S L + LP+ +++ ++ A
Sbjct: 486 FSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPI---IMVVAFSMCIICLLMA 542
Query: 276 GRNTQQYLASALWAGVTA-GVVAMIKVNGRHLCSRPRL 166
G + LA L+ GV + G +I NG+ PRL
Sbjct: 543 GDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRL 580
>sp|A4VCH0|SAC1B_DANRE Phosphatidylinositide phosphatase SAC1-B OS=Danio rerio
GN=sacm1lb PE=2 SV=2
Length = 586
Score = 330 bits (845), Expect = 3e-089
Identities = 196/577 (33%), Positives = 303/577 (52%), Gaps = 6/577 (1%)
Frame = -3
Query: 1884 YDHLQLLEFPDKYVIKPVDSPHEGFSVDRRDGNIKPLDDNTSSVNATKVSTIFGVGGTIR 1705
Y+ L P+K+ I+ D + V R L + I GV GT+R
Sbjct: 5 YERFNLHSTPEKFYIEACDDGADDVLVIDRVSTEMTLAGIKDIPPSGITRPICGVMGTVR 64
Query: 1704 LLAGTYLLVITSREEAGTFLGFPIFRVTAMKFLPCNANLRFATAQERRDEAYFRTLLQAL 1525
L+AG YL+VIT + + G G +++ + + T + +D F T++ +
Sbjct: 65 LVAGMYLIVITRKRKVGDLFGHTVWKAVEFDVISYKKTILHLTDIQMQDNKTFLTMINNV 124
Query: 1524 ETTPGLYFSYETDLTVNLQRRCKLAVGWTSKPMWKQADPRYVWNWHLLEELI-ECKLDGF 1348
T G YF + DLT QR + + + ++AD R++WN +LL E+I + +L F
Sbjct: 125 LNTDGFYFCTDYDLTHTQQRLSNTSPDFQEMSLLERADQRFMWNGNLLREIIAQPELHKF 184
Query: 1347 ITPLLQGSYQVAELQLKNSPSVISLISRRCTRRLGTRMWRRGANLEGDTANFVESEQIME 1168
P++ G + + +ISRR R G R + RG + EG ANFVE+EQI++
Sbjct: 185 AFPVIHGFIVMKPCCINGKVFEWIIISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVQ 244
Query: 1167 INGFKFSLLQVRGSIPLLWEQIVDLSYKPQLKINKHEDTPKVVQRHFHDLSQRYGEIMVV 988
N + S +Q RGSIP W Q +L YKP+ I+K + ++RHF YG+ +++
Sbjct: 245 FNNARASFVQTRGSIPFFWSQRPNLKYKPKPLISKDTNHMDGLRRHFESQVLIYGKQVIL 304
Query: 987 NLTDQDGAEGELGKAYATEMARLPN--VRFVAFDFHHICGTTNFDNLGVLYEEIGDEFEK 814
NL +Q G+E L +A+A ++ + N ++++AFDFH C + L +L + + D E+
Sbjct: 305 NLVNQKGSELPLEQAFAKMVSSMENGFIKYIAFDFHKECSKMRWHRLQILVDAVSDMQEE 364
Query: 813 QGYFLVDADGNILEEQKGVVRSNCIDCLDRTNVTQNYMAQKSLNLQLQRIGVLDSKECVS 634
GYF+V +DG +L EQ G RSNC+DCLDRTNV Q+ +A++SL QLQR+GVL + +
Sbjct: 365 FGYFMVSSDGKVLSEQSGTFRSNCMDCLDRTNVIQSLLARRSLQSQLQRMGVLHVGQKIE 424
Query: 633 MFGDDYTKFRTIWAEQGDEISLQYAGTYALKGDLVRYGKQTVSGAIKDGISAMSRYYLNN 454
D ++ WA+ + + QYAGT ALK D R GK+T G + DG ++M RYY NN
Sbjct: 425 EQADFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHWGLVMDGWNSMIRYYKNN 484
Query: 453 FQDGVRQDALDLISGRYTVGTNSPSQLQPIGGSQPSFLPVASALLIGGVTVTSFTFHQAG 274
F DG RQD++DL G Y+V + L P+ + + +++ ++ AG
Sbjct: 485 FSDGFRQDSIDLFLGNYSV--DETDSLTPLHVKKDWKFLLLPVIMVVAFSMCIICLLMAG 542
Query: 273 RNTQQYLASAL-WAGVTAGVVAMIKVNGRHLCSRPRL 166
+ LA L W +A A+I VNGR P+L
Sbjct: 543 DTWTETLAYVLFWGMASALTAAVIVVNGREFVDAPKL 579
>sp|Q9NTJ5|SAC1_HUMAN Phosphatidylinositide phosphatase SAC1 OS=Homo sapiens
GN=SACM1L PE=1 SV=2
Length = 587
Score = 330 bits (845), Expect = 3e-089
Identities = 205/578 (35%), Positives = 306/578 (52%), Gaps = 8/578 (1%)
Frame = -3
Query: 1884 YDHLQLLEFPDKYVIKPVDSPHEGFSVDRRDGNIKPLDDNTSSVNATKVSTIFGVGGTIR 1705
Y+ L+L P+K+ ++ D + R L + IFG+ GTI
Sbjct: 6 YEQLKLHITPEKFYVEACDDGADDVLTIDRVSTEVTLAVKKDVPPSAVTRPIFGILGTIH 65
Query: 1704 LLAGTYLLVITSREEAGTFLGFPIFRVTAMKFLPCNANLRFATAQERRDEAYFRTLLQAL 1525
L+AG YL+VIT + + G F +++ T L + T + +D F +L +
Sbjct: 66 LVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHV 125
Query: 1524 ETTPGLYFSYETDLTVNLQRRCKLAVGWTSKPMWKQADPRYVWNWHLLEEL-IECKLDGF 1348
G YFS DLT LQR + + + ++AD R+VWN HLL EL + ++ F
Sbjct: 126 LNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRF 185
Query: 1347 ITPLLQGSYQVAELQLKNSPSVISLISRRCTRRLGTRMWRRGANLEGDTANFVESEQIME 1168
P+L G + + LISRR R G R + RG + EG ANFVE+EQI+
Sbjct: 186 ALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVH 245
Query: 1167 INGFKFSLLQVRGSIPLLWEQIVDLSYKPQLKINKHEDTPKVVQRHFHDLSQRYGEIMVV 988
NG K S +Q RGSIP+ W Q +L YKP +I+K + QRHF YG+ +++
Sbjct: 246 YNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVII 305
Query: 987 NLTDQDGAEGELGKAYATEMARLPN--VRFVAFDFHHICGTTNFDNLGVLYEEIGDEFEK 814
NL +Q G+E L + +AT ++ L + +R++AFDFH C +D L +L +++ + ++
Sbjct: 306 NLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDE 365
Query: 813 QGYFLVDADGNILEEQKGVVRSNCIDCLDRTNVTQNYMAQKSLNLQLQRIGVLDSKECVS 634
YFLVD+ G ++ Q+GV RSNC+DCLDRTNV Q+ +A++SL QLQR+GVL + +
Sbjct: 366 LSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLE 425
Query: 633 MFGDDYTKFRTIWAEQGDEISLQYAGTYALKGDLVRYGKQTVSGAIKDGISAMSRYYLNN 454
+ ++ WA+ + + QYAGT ALK D R GK+T G I DG ++M RYY NN
Sbjct: 426 EQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNN 485
Query: 453 FQDGVRQDALDLISGRYTVG-TNSPSQLQPIGGSQPSFLPVASALLIGGVTVTSFTFHQA 277
F DG RQD++DL G Y+V S S L + LP+ +++ ++ A
Sbjct: 486 FSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPI---IMVVAFSMCIICLLMA 542
Query: 276 GRNTQQYLASALWAGVTA-GVVAMIKVNGRHLCSRPRL 166
G + LA L+ GV + G +I NG+ PRL
Sbjct: 543 GDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRL 580
>sp|A1L244|SAC1A_DANRE Phosphatidylinositide phosphatase SAC1-A OS=Danio rerio
GN=sacm1la PE=2 SV=1
Length = 586
Score = 328 bits (840), Expect = 1e-088
Identities = 188/526 (35%), Positives = 288/526 (54%), Gaps = 6/526 (1%)
Frame = -3
Query: 1731 IFGVGGTIRLLAGTYLLVITSREEAGTFLGFPIFRVTAMKFLPCNANLRFATAQERRDEA 1552
I G+ GTIRL+AG YL+VIT +++ G LG +++ + + + T + +D
Sbjct: 56 ICGIMGTIRLVAGVYLIVITKKKKVGDLLGHAVWKASDFDIISYKKTVLHLTDNQMQDNK 115
Query: 1551 YFRTLLQALETTPGLYFSYETDLTVNLQRRCKLAVGWTSKPMWKQADPRYVWNWHLLEE- 1375
F ++L ++ T G YF+ + DLT LQR + + + ++AD R+VWN HLL E
Sbjct: 116 VFLSMLNSVLNTDGFYFATDYDLTHTLQRLSNTSPEFQEMTLLERADQRFVWNGHLLREF 175
Query: 1374 LIECKLDGFITPLLQGSYQVAELQLKNSPSVISLISRRCTRRLGTRMWRRGANLEGDTAN 1195
+ + +L F+ P++ G + + +LISRR R G R + RG + EG AN
Sbjct: 176 MAQPELHRFVFPVIHGFIAMRSCCINGKIFDWNLISRRSCFRAGVRYYVRGIDSEGHAAN 235
Query: 1194 FVESEQIMEINGFKFSLLQVRGSIPLLWEQIVDLSYKPQLKINKHEDTPKVVQRHFHDLS 1015
FVE+EQI++ NG K S +Q RGSIP W Q +L YKP+ +I+K + QRHF
Sbjct: 236 FVETEQIIQYNGAKASFIQTRGSIPFYWSQRPNLKYKPKPQISKSINHLDGFQRHFDSQI 295
Query: 1014 QRYGEIMVVNLTDQDGAEGELGKAYATEMARLPN--VRFVAFDFHHICGTTNFDNLGVLY 841
YG+ +++NL +Q G+E L +A+A + L N ++++AFDFH C + L +L
Sbjct: 296 IIYGKQVILNLVNQKGSEKPLEQAFAKMVGSLGNGMIKYIAFDFHKECSRMRWHRLQILV 355
Query: 840 EEIGDEFEKQGYFLVDADGNILEEQKGVVRSNCIDCLDRTNVTQNYMAQKSLNLQLQRIG 661
+ + + ++ GYFLVD+DG++ +Q G RSNC+DCLDRTNV Q+ +A++SL QL+R+
Sbjct: 356 DTVAELQDEFGYFLVDSDGSVQMQQDGTFRSNCMDCLDRTNVVQSLLARRSLQSQLERMA 415
Query: 660 VLDSKECVSMFGDDYTKFRTIWAEQGDEISLQYAGTYALKGDLVRYGKQTVSGAIKDGIS 481
VL + + D ++ WA+ + + QYAGT ALK D R GK+T G + DG +
Sbjct: 416 VLHVGQRIEEQADFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQWGLLMDGWN 475
Query: 480 AMSRYYLNNFQDGVRQDALDLISGRYTVGTNSPSQLQPIGGSQPSFLPVASALLIGGVTV 301
+M RYY NNF DG RQD++DL G Y V P+ + +++ ++
Sbjct: 476 SMIRYYKNNFSDGFRQDSIDLFLGNYAV--EEADMNTPLHEPKDWKFLTLPIIMVVAFSM 533
Query: 300 TSFTFHQAGRNTQQYLASAL-WAGVTAGVVAMIKVNGRHLCSRPRL 166
AG + LA L W + +I NGR PRL
Sbjct: 534 CIICLLMAGDTWTETLAYVLFWGSASVVTGGVILFNGRDFVDAPRL 579
>sp|Q9EP69|SAC1_MOUSE Phosphatidylinositide phosphatase SAC1 OS=Mus musculus
GN=Sacm1l PE=2 SV=1
Length = 587
Score = 327 bits (838), Expect = 2e-088
Identities = 200/578 (34%), Positives = 305/578 (52%), Gaps = 8/578 (1%)
Frame = -3
Query: 1884 YDHLQLLEFPDKYVIKPVDSPHEGFSVDRRDGNIKPLDDNTSSVNATKVSTIFGVGGTIR 1705
Y+HL+L P+K+ ++ D + + R L + IFG+ GTI
Sbjct: 6 YEHLKLHITPEKFYVEACDDGADDVLIIDRVSTEVTLAVKKDVPPSAVTRPIFGILGTIH 65
Query: 1704 LLAGTYLLVITSREEAGTFLGFPIFRVTAMKFLPCNANLRFATAQERRDEAYFRTLLQAL 1525
L+AG YL+VIT + + G ++R T L + T + +D F +L +
Sbjct: 66 LVAGNYLVVITKKMKVGECFNHAVWRATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHV 125
Query: 1524 ETTPGLYFSYETDLTVNLQRRCKLAVGWTSKPMWKQADPRYVWNWHLLEEL-IECKLDGF 1348
+ G YFS DLT LQR + + + ++AD R+VWN HLL EL + ++ F
Sbjct: 126 LSMDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRF 185
Query: 1347 ITPLLQGSYQVAELQLKNSPSVISLISRRCTRRLGTRMWRRGANLEGDTANFVESEQIME 1168
P+L G + + LISRR R G R + RG + EG ANFVE+EQI+
Sbjct: 186 ALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVH 245
Query: 1167 INGFKFSLLQVRGSIPLLWEQIVDLSYKPQLKINKHEDTPKVVQRHFHDLSQRYGEIMVV 988
+G + S +Q RGSIP+ W Q +L YKP +I+K + QRHF YG+ +++
Sbjct: 246 YSGNRASFVQTRGSIPIFWSQRPNLKYKPHPQISKVANHMDGFQRHFDSQVIIYGKQVII 305
Query: 987 NLTDQDGAEGELGKAYATEMARLPN--VRFVAFDFHHICGTTNFDNLGVLYEEIGDEFEK 814
NL + G+E L + +A ++ L + +R++AFDFH C +D L +L +++ + ++
Sbjct: 306 NLVNHKGSEKPLEQTFANMVSSLGSGMIRYIAFDFHKECKNMRWDRLSILLDQVAEMQDE 365
Query: 813 QGYFLVDADGNILEEQKGVVRSNCIDCLDRTNVTQNYMAQKSLNLQLQRIGVLDSKECVS 634
YFLVD+ G ++ Q GV RSNC+DCLDRTNV Q+ +A++SL QLQR+GVL + +
Sbjct: 366 LSYFLVDSAGKVVTNQDGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLE 425
Query: 633 MFGDDYTKFRTIWAEQGDEISLQYAGTYALKGDLVRYGKQTVSGAIKDGISAMSRYYLNN 454
+ ++ WA+ + + QYAGT ALK D R GK+T G + DG +++ RYY NN
Sbjct: 426 EQDEFEKTYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLLMDGFNSLLRYYKNN 485
Query: 453 FQDGVRQDALDLISGRYTVG-TNSPSQLQPIGGSQPSFLPVASALLIGGVTVTSFTFHQA 277
F DG RQD++DL G Y+V S S L + LP+ +++ ++ A
Sbjct: 486 FSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPI---IMVVAFSMCIICLLMA 542
Query: 276 GRNTQQYLASALWAGVTA-GVVAMIKVNGRHLCSRPRL 166
G + LA L+ GV + G +I NG+ PRL
Sbjct: 543 GDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRL 580
>sp|Q55AW9|SAC1_DICDI Phosphatidylinositide phosphatase SAC1 OS=Dictyostelium
discoideum GN=sac1 PE=3 SV=1
Length = 581
Score = 288 bits (735), Expect = 2e-076
Identities = 172/452 (38%), Positives = 262/452 (57%), Gaps = 13/452 (2%)
Frame = -3
Query: 1746 TKVSTIFGVGGTIRLLAGTYLLVITSREEAGTFLGFPIFRVTAMKFLPCNANLRFATAQE 1567
T++ + G+ G I+L++G YL++ T G I+++ ++ +P N + +
Sbjct: 48 TRIENVKGIIGCIQLVSGHYLMIFKEHNHVATVTGKKIYQMKDVELIPFFPNQQSLVSIP 107
Query: 1566 RRD-EAYFRTLLQALETTPGLYFSYETDLTVNLQRRCKLAVGWTS-KPMWKQADPRYVWN 1393
+D E ++++ L ++ YFSY+ D T+ LQR+ TS + ++ D R+ WN
Sbjct: 108 DQDAEEQHLSMIRWLLSSENFYFSYDYDFTLTLQRQYSTTTTTTSGSSLGERCDSRFFWN 167
Query: 1392 WHLLEELI-ECKLDGFITPLLQGSYQVAELQLKNSPSVISLISRRCTRRLGTRMWRRGAN 1216
+ L E L +I P+ G E + +LISRR R GTR RG +
Sbjct: 168 EKYVTILSKEHGLGDWILPITMG---FVESKTLGGTCQFTLISRRNLNRSGTRYNVRGID 224
Query: 1215 LEGDTANFVESEQIMEINGFKF-SLLQVRGSIPLLWEQIVDLSYKPQLKI-NKHEDTPKV 1042
+G+ AN VE+EQI+EI F S +QVRGSIPLLW Q L YKP +K ++ +
Sbjct: 225 KKGNVANNVETEQIIEIKENTFTSFVQVRGSIPLLWSQFPTLKYKPSVKFYGDEKENSQA 284
Query: 1041 VQRHFHDLSQRYGEIMVVNLTDQDGAEGELGKAYATEMARLPNVRFVAFDFHHICGTTNF 862
+++HF L Q YG VVNL D+ GAE +LG+AY + L +V +V FDFH IC +
Sbjct: 285 LEQHFKQLHQLYGSTTVVNLIDRKGAELKLGEAYEERVKSLKDVHYVWFDFHSICKGMRY 344
Query: 861 DNLGVLYEEIGDEFEKQGYFLVDADGNILEEQKGVVRSNCIDCLDRTNVTQNYMAQKSLN 682
D L +L +++ D+ ++ G+F V+ DG I+++Q+GV R+NCID LDRTNV Q+ + + SL
Sbjct: 345 DKLSILMDQLKDDLKQYGFFFVE-DGKIVQKQQGVFRTNCIDNLDRTNVVQSLITRHSLE 403
Query: 681 LQLQRIGVLDSKECVSMF-GDDYT-KFRTIWAEQGDEISLQYAGTYALKGDLVRYGKQTV 508
Q+ VL+ + + F GD + F+ IWA+ GD IS QY+GT ALK D R GK+
Sbjct: 404 NQM--ASVLNKQIPSTTFKGDQFEYVFKNIWADHGDAISTQYSGTGALKNDFTRTGKRNF 461
Query: 507 SGAIKDGISAMSRYYLNNFQDGVRQDALDLIS 412
G ++DG +++ RYYLNNF+DG RQD+ L +
Sbjct: 462 QGVLRDGENSVKRYYLNNFKDGFRQDSYFLFT 493
>sp|O14127|YF51_SCHPO Uncharacterized protein C3C7.01c OS=Schizosaccharomyces
pombe GN=SPAC3C7.01c PE=2 SV=2
Length = 611
Score = 238 bits (607), Expect = 1e-061
Identities = 167/499 (33%), Positives = 244/499 (48%), Gaps = 29/499 (5%)
Frame = -3
Query: 1860 FPDKYVIKPVDSPHEGFSVDRRDGNIKPLDDNTSSVNATKVSTIFGVGGTIRLLAGTYLL 1681
FPD + +DR DG + N+ ++ T + G IRL Y++
Sbjct: 8 FPDSIYLS-CSKKKASLRIDRVDGCLSL--SNSLDLSKTPDYNNVQLYGFIRLKIYKYVV 64
Query: 1680 VITSREEAGTFLGFPIFRVTAMKFLPCNANLRFATAQ---ERRDEAYFRTLLQALETTPG 1510
++TS + LG I+R P L F+T + +E ++ +LL +
Sbjct: 65 LVTSCDLHAAILGNNIYRARKFAIFPITRTLPFSTGLLNIKDEEELHYISLLNKHLSKGQ 124
Query: 1509 LYFSYETDLTVNLQRRCKLAVGWTSKPMWKQADPRYVWNWHLLEELIECK-----LDGFI 1345
+ FS DLT +LQR L V S + + + R+ WN + ELIE +I
Sbjct: 125 ILFSPTLDLTCSLQR---LRVLTQSFELTSKYNYRFFWNKYAFHELIELTNKDLGFQEWI 181
Query: 1344 TPLLQGSYQVAELQLKNSPSVISLISRRCTRRLGTRMWRRGANLEGDTANFVESEQIMEI 1165
P++QG+ + LK + +I+R GTR + RG N +G ANF E EQI+ I
Sbjct: 182 QPMIQGNIAITNSFLKTYNLRLCVITRHSPDYAGTRYFTRGVNAQGSAANFNEIEQIIMI 241
Query: 1164 NG-------FKFSLLQVRGSIPLLWEQIVDLSYKPQLKINKHEDTPKVVQRHFHDLSQRY 1006
S Q+RGSIP+ W ++ DL Y+P L + + + V +HF +L+ Y
Sbjct: 242 ESPITLEEQMVLSFTQIRGSIPMFWAEVNDLHYRPLLSLQPLDYSETVFGKHFQELANDY 301
Query: 1005 GE-IMVVNLTDQDGAEGELGKAY--ATEMARLPNVRFVAFDFHHICGTTNFDNLGVLYEE 835
G+ ++VVNL DQ G E L + + + P + +V +D+H NL + E
Sbjct: 302 GDNLVVVNLLDQKGREAPLRSGFEKLCKRNKNPPLSYVYYDYH----KQGSRNLPLFLAE 357
Query: 834 IGDEFEKQGYFLVDADGNILEEQKGVVRSNCIDCLDRTNVTQNYMAQKSLNLQLQRIGVL 655
I +G + + Q VR+NC+DCLDRTNV Q +AQ LN+QL IGVL
Sbjct: 358 I-QSLLIEGKYYAEHGSKTTAMQTNFVRTNCMDCLDRTNVIQTSIAQFILNMQLHDIGVL 416
Query: 654 DSKECVSMFGDDYTKFRTIWAEQGDEISLQYAGTYALKGDLVRYGKQTVSGAIKDGISAM 475
S E + + FR IWA GD IS Y GT ALKGD+ R+G +T+ GA KD ++
Sbjct: 417 SSSESLEEYDSFLQDFRLIWANTGDYISDLYTGTPALKGDVTRHGTRTIFGAFKDLLNCF 476
Query: 474 SRYYLNNFQDGVRQDALDL 418
RY LNNF DG+ QD+ DL
Sbjct: 477 RRYILNNFFDGMLQDSYDL 495
>sp|A8E7C5|SAC2_DANRE Phosphatidylinositide phosphatase SAC2 OS=Danio rerio
GN=inpp5f PE=3 SV=1
Length = 1120
Score = 218 bits (553), Expect = 2e-055
Identities = 114/294 (38%), Positives = 179/294 (60%), Gaps = 7/294 (2%)
Frame = -3
Query: 1281 ISLISRRCTRRLGTRMWRRGANLEGDTANFVESEQIMEINGFKFSLLQVRGSIPLLWEQI 1102
++LISRR R G R RRG + +G AN+VE+EQ++ ++ S +Q RGS+P+ W Q
Sbjct: 278 VALISRRSRHRAGMRYKRRGVDTDGHVANYVETEQLIHVHSHTLSFVQTRGSVPVFWSQ- 336
Query: 1101 VDLSYKPQLKINKHE-DTPKVVQRHFHDLSQRYGEIMVVNLTDQDGAEGELGKAYATE-- 931
Y P+ +I K E +T HF + Y +++++NL DQ+G E +G AY +
Sbjct: 337 AGYRYNPRPRIEKGERETMPYFASHFEKEVETYKKLVIINLVDQNGREKIIGDAYLKQVL 396
Query: 930 MARLPNVRFVAFDFHHICGTTNFDNLGVLYEEIGDEFEKQGYFLVDADGNILEEQKGVVR 751
+ PN+ +V+FDFH C F+N+ L + I D + VD G ++ +Q+G+ R
Sbjct: 397 LYNNPNLTYVSFDFHEHCRGMKFENVQTLTDAIYDIITDMRWAWVDQAG-VICQQEGIFR 455
Query: 750 SNCIDCLDRTNVTQNYMAQKSLNLQLQRIGVLDSKECVSMFGDDYTKFRTIWAEQGDEIS 571
NC+DCLDRTNV Q +A+ + QL+++GV+ ++ + + Y ++ +WA GD IS
Sbjct: 456 VNCMDCLDRTNVVQAAIARVIMEQQLKKLGVMPPEQPLPL--KCYRIYQVMWANNGDTIS 513
Query: 570 LQYAGTYALKGDLVRYGKQTVSGAIKDGISAMSRYYLNNFQDGVRQDALDLISG 409
QYAGT ALKGD R G++ ++G +KDG+++ +RYYLN F+D RQ +DL+ G
Sbjct: 514 RQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFRDAYRQAVIDLMMG 567
>sp|Q8CDA1|SAC2_MOUSE Phosphatidylinositide phosphatase SAC2 OS=Mus musculus
GN=Inpp5f PE=1 SV=1
Length = 1132
Score = 209 bits (530), Expect = 9e-053
Identities = 112/295 (37%), Positives = 180/295 (61%), Gaps = 7/295 (2%)
Frame = -3
Query: 1284 VISLISRRCTRRLGTRMWRRGANLEGDTANFVESEQIMEINGFKFSLLQVRGSIPLLWEQ 1105
+++LISRR R G R RRG + G+ AN+VE+EQ++ ++ S +Q RGS+P+ W Q
Sbjct: 277 LVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHHHTLSFIQTRGSVPVFWSQ 336
Query: 1104 IVDLSYKPQLKINKHE-DTPKVVQRHFHDLSQRYGEIMVVNLTDQDGAEGELGKAYATEM 928
V Y P+ +++K E +T HF + + Y + ++VNL DQ G E +G AY ++
Sbjct: 337 -VGYRYNPRPRLDKSEKETVDCFCAHFEEQLKIYKKQVIVNLVDQAGREKIIGDAYLKQV 395
Query: 927 ARL--PNVRFVAFDFHHICGTTNFDNLGVLYEEIGDEFEKQGYFLVDADGNILEEQKGVV 754
P + +V+FDFH C F+N+ L + I D + VD G ++ +Q+G+
Sbjct: 396 LLFNNPKLTYVSFDFHEHCRGMKFENVQTLTDAIHDIIIDMKWCWVDQAG-VICKQEGIF 454
Query: 753 RSNCIDCLDRTNVTQNYMAQKSLNLQLQRIGVLDSKECVSMFGDDYTKFRTIWAEQGDEI 574
R NC+DCLDRTNV Q +A+ + QL+++GV+ ++ + + + ++ +WA GD I
Sbjct: 455 RVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCN--RTYQIMWANNGDSI 512
Query: 573 SLQYAGTYALKGDLVRYGKQTVSGAIKDGISAMSRYYLNNFQDGVRQDALDLISG 409
S QYAGT ALKGD R G++ ++G +KDG+++ +RYYL+ F+D RQ +DL+ G
Sbjct: 513 SRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLSRFKDAYRQAVIDLMQG 567
>sp|Q9Y2H2|SAC2_HUMAN Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens
GN=INPP5F PE=1 SV=3
Length = 1132
Score = 207 bits (526), Expect = 3e-052
Identities = 111/295 (37%), Positives = 179/295 (60%), Gaps = 7/295 (2%)
Frame = -3
Query: 1284 VISLISRRCTRRLGTRMWRRGANLEGDTANFVESEQIMEINGFKFSLLQVRGSIPLLWEQ 1105
+++LISRR R G R RRG + G+ AN+VE+EQ++ ++ S +Q RGS+P+ W Q
Sbjct: 277 LVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPVFWSQ 336
Query: 1104 IVDLSYKPQLKINKHE-DTPKVVQRHFHDLSQRYGEIMVVNLTDQDGAEGELGKAYATEM 928
V Y P+ ++++ E +T HF + Y + +++NL DQ G E +G AY ++
Sbjct: 337 -VGYRYNPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQAGREKIIGDAYLKQV 395
Query: 927 ARLPN--VRFVAFDFHHICGTTNFDNLGVLYEEIGDEFEKQGYFLVDADGNILEEQKGVV 754
N + +V+FDFH C F+N+ L + I D + VD G ++ +Q+G+
Sbjct: 396 LLFNNSHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVDEAG-VICKQEGIF 454
Query: 753 RSNCIDCLDRTNVTQNYMAQKSLNLQLQRIGVLDSKECVSMFGDDYTKFRTIWAEQGDEI 574
R NC+DCLDRTNV Q +A+ + QL+++GV+ ++ + + + ++ +WA GD I
Sbjct: 455 RVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRI--YQIMWANNGDSI 512
Query: 573 SLQYAGTYALKGDLVRYGKQTVSGAIKDGISAMSRYYLNNFQDGVRQDALDLISG 409
S QYAGT ALKGD R G++ ++G +KDG+++ +RYYLN F+D RQ +DL+ G
Sbjct: 513 SRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQG 567
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0
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