BLASTX 7.6.2
Query= UN17005 /QuerySize=1198
(1197 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q94JW0|DOHH_ARATH Deoxyhypusine hydroxylase OS=Arabidopsis th... 531 6e-150
sp|Q2QXB3|DOHH1_ORYSJ Deoxyhypusine hydroxylase-A OS=Oryza sativ... 416 2e-115
sp|Q2QLW3|DOHH2_ORYSJ Deoxyhypusine hydroxylase-B OS=Oryza sativ... 409 3e-113
sp|Q5ZIP3|DOHH_CHICK Deoxyhypusine hydroxylase OS=Gallus gallus ... 259 4e-068
sp|Q9BU89|DOHH_HUMAN Deoxyhypusine hydroxylase OS=Homo sapiens G... 258 5e-068
sp|Q99LN9|DOHH_MOUSE Deoxyhypusine hydroxylase OS=Mus musculus G... 257 2e-067
sp|Q7ZUX6|DOHH_DANRE Deoxyhypusine hydroxylase OS=Danio rerio GN... 256 3e-067
sp|Q66KT3|DOHH_XENLA Deoxyhypusine hydroxylase OS=Xenopus laevis... 243 3e-063
sp|Q9V9U4|DOHH_DROME Deoxyhypusine hydroxylase OS=Drosophila mel... 225 5e-058
sp|Q297S2|DOHH_DROPS Deoxyhypusine hydroxylase OS=Drosophila pse... 222 4e-057
sp|Q59Z14|DOHH_CANAL Deoxyhypusine hydroxylase OS=Candida albica... 212 4e-054
sp|Q6CHJ7|DOHH_YARLI Deoxyhypusine hydroxylase OS=Yarrowia lipol... 212 4e-054
sp|Q9P6K9|DOHH_SCHPO Deoxyhypusine hydroxylase OS=Schizosaccharo... 210 2e-053
sp|Q6FUV3|DOHH_CANGA Deoxyhypusine hydroxylase OS=Candida glabra... 199 5e-050
sp|Q6CV81|DOHH_KLULA Deoxyhypusine hydroxylase OS=Kluyveromyces ... 198 1e-049
sp|P47120|DOHH_YEAST Deoxyhypusine hydroxylase OS=Saccharomyces ... 196 3e-049
sp|Q752Z8|DOHH_ASHGO Deoxyhypusine hydroxylase OS=Ashbya gossypi... 184 1e-045
sp|Q5PPJ4|DOHH_RAT Deoxyhypusine hydroxylase OS=Rattus norvegicu... 159 4e-038
sp|Q0VC53|DOHH_BOVIN Deoxyhypusine hydroxylase OS=Bos taurus GN=... 149 6e-035
>sp|Q94JW0|DOHH_ARATH Deoxyhypusine hydroxylase OS=Arabidopsis thaliana
GN=At3g58180 PE=2 SV=1
Length = 314
Score = 531 bits (1366), Expect = 6e-150
Identities = 276/314 (87%), Positives = 296/314 (94%), Gaps = 6/314 (1%)
Frame = +3
Query: 111 NGVVN---DVEKFLCERLVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAH 281
NG V+ ++EKFLCERLVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAH
Sbjct: 4 NGSVSSMVNLEKFLCERLVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAH 63
Query: 282 EAAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPA 461
EAAFALGQMQDAEA+PALESVLNDMSLHPIVRHEAAEALGAIGLAGN ILKKSL DPA
Sbjct: 64 EAAFALGQMQDAEAIPALESVLNDMSLHPIVRHEAAEALGAIGLAGNVNILKKSLSSDPA 123
Query: 462 QEVRETCELALKRIEELSNVDAEKELGVTTETERSPFMSVDPAAPAAAFSSVQQLREILL 641
QEVRETCELALKRIE++SNVDAE + ++ TE+SPFMSVDPA PAA+FSSV QLR++LL
Sbjct: 124 QEVRETCELALKRIEDMSNVDAENQ---SSTTEKSPFMSVDPAGPAASFSSVHQLRQVLL 180
Query: 642 DETKGMYERYAALFALRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLS 821
DETKGMYERYAALFALRNHGGE+AVSAIVDSLSA+SALLRHEVAYVLGQLQ+K ALATLS
Sbjct: 181 DETKGMYERYAALFALRNHGGEEAVSAIVDSLSASSALLRHEVAYVLGQLQSKTALATLS 240
Query: 822 KILRDVNEHPMVRHEAAEALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFENFG 1001
K+LRDVNEHPMVRHEAAEALGSIADEQSIALL+EF +DPEPIV+QSCEVALSMLEFEN G
Sbjct: 241 KVLRDVNEHPMVRHEAAEALGSIADEQSIALLEEFSKDPEPIVAQSCEVALSMLEFENSG 300
Query: 1002 KSFEFFFTQDPLVH 1043
KSFEFFFTQDPLVH
Sbjct: 301 KSFEFFFTQDPLVH 314
>sp|Q2QXB3|DOHH1_ORYSJ Deoxyhypusine hydroxylase-A OS=Oryza sativa subsp.
japonica GN=Os12g0163300 PE=2 SV=1
Length = 319
Score = 416 bits (1069), Expect = 2e-115
Identities = 224/324 (69%), Positives = 261/324 (80%), Gaps = 6/324 (1%)
Frame = +3
Query: 78 MEPNGSASSTENGVVNDVEKFLCERLVDQSQPISERFRALFSLRNLKGPGPRNALILASR 257
ME A+S+ G ++EKFLC+ L+D +QPI+ERFRALFSLRNL G GPR AL+ A+R
Sbjct: 1 MESAEVAASSTFGPTPEMEKFLCDLLLDTAQPIAERFRALFSLRNLHGDGPRCALLQAAR 60
Query: 258 DSSNLLAHEAAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILK 437
DSSNLLAHEAAFALGQMQDAEA+PALE+VL D+SLHPIVRHEAAEALGAIGL + +L+
Sbjct: 61 DSSNLLAHEAAFALGQMQDAEAIPALEAVLKDLSLHPIVRHEAAEALGAIGLEKSIPLLE 120
Query: 438 KSLVLDPAQEVRETCELALKRIEELSNVDAEKELGVTTETERSPFMSVDPAAPAAAFSSV 617
+SL DPA EV+ETCELAL+RIE+ +K GV+ T SPF+SVDPA PA SV
Sbjct: 121 ESLAADPAVEVQETCELALRRIEQ------QKNAGVSESTTISPFLSVDPALPAKQGLSV 174
Query: 618 QQLREILLDETKGMYERYAALFALRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQN 797
QLREILL+E + MYERYAALFALRN + AVSAIV +L A SALL+HEVAYVLGQLQN
Sbjct: 175 HQLREILLNEQESMYERYAALFALRNDSRDAAVSAIVAALGAKSALLKHEVAYVLGQLQN 234
Query: 798 KAALATLSKILRDVNEHPMVRHEAAEALGSIADEQSIALLQEFLRDPEPIVSQSCEVALS 977
KAA LS +L++V+EHPMVRHEAAEALGSIAD++SIALL+EF +DPEPIVSQSCEVALS
Sbjct: 235 KAASDALSTVLKNVDEHPMVRHEAAEALGSIADQESIALLEEFAKDPEPIVSQSCEVALS 294
Query: 978 MLEFENFGKSFEFFFTQDPLVH*E 1049
MLE+E GKSFEF F Q P V E
Sbjct: 295 MLEYERSGKSFEFLFLQTPGVQQE 318
>sp|Q2QLW3|DOHH2_ORYSJ Deoxyhypusine hydroxylase-B OS=Oryza sativa subsp.
japonica GN=Os12g0626100 PE=2 SV=1
Length = 302
Score = 409 bits (1049), Expect = 3e-113
Identities = 216/307 (70%), Positives = 253/307 (82%), Gaps = 6/307 (1%)
Frame = +3
Query: 129 VEKFLCERLVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAHEAAFALGQM 308
+E FLC+RL+D +QPI+ERFRALFSLRNL+G PR AL+ A+RDSSNLLAHEAAFALGQM
Sbjct: 1 MEGFLCDRLLDAAQPIAERFRALFSLRNLRGDAPRRALLQAARDSSNLLAHEAAFALGQM 60
Query: 309 QDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCEL 488
QDAEA+PALE+VL D+SLHPIVRHEAAEALGAIGL + +L++SL +DPA EV+ETCEL
Sbjct: 61 QDAEAIPALEAVLKDLSLHPIVRHEAAEALGAIGLEKSISLLEESLAVDPAVEVQETCEL 120
Query: 489 ALKRIEELSNVDAEKELGVTTETERSPFMSVDPAAPAAAFSSVQQLREILLDETKGMYER 668
A++RIEE N GV + T SPF+SVDPA PA V+QLRE+LL+E + MYER
Sbjct: 121 AIRRIEEQKNTS-----GVESATV-SPFLSVDPALPAKQGLPVEQLRELLLNEQESMYER 174
Query: 669 YAALFALRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEH 848
YAALFALRN G+ AVSAIV +L SALLRHEVAYVLGQLQNKAA LS +L++V+EH
Sbjct: 175 YAALFALRNDSGDAAVSAIVAALGVKSALLRHEVAYVLGQLQNKAASDALSTVLKNVDEH 234
Query: 849 PMVRHEAAEALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFENFGKSFEFFFTQ 1028
PMVRHEAAEALGSIAD++SIALL+EF +DPEPIVSQSCEVALSMLE+E GK+FEF F Q
Sbjct: 235 PMVRHEAAEALGSIADQESIALLEEFAKDPEPIVSQSCEVALSMLEYERSGKAFEFLFPQ 294
Query: 1029 DPLVH*E 1049
P V E
Sbjct: 295 TPQVQQE 301
>sp|Q5ZIP3|DOHH_CHICK Deoxyhypusine hydroxylase OS=Gallus gallus GN=DOHH PE=2
SV=1
Length = 299
Score = 259 bits (660), Expect = 4e-068
Identities = 147/288 (51%), Positives = 191/288 (66%), Gaps = 11/288 (3%)
Frame = +3
Query: 153 LVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAHEAAFALGQMQDAEAVPA 332
L+D +QP+ RFRALF+LRNL GP + ++ DSS LL HE AF LGQM+D A+PA
Sbjct: 14 LLDAAQPLPARFRALFTLRNLGGPAAIDCIVRGFADSSALLKHELAFCLGQMRDRAAIPA 73
Query: 333 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCELALKRIEEL 512
L VL D P+VRHEA EALGAIG ++L++ DP EV ETC+LA++R+E L
Sbjct: 74 LLGVLQDSQQEPMVRHEAGEALGAIGDPEVLDVLRR-YSEDPVVEVAETCQLAVRRLEWL 132
Query: 513 SNVDAEKELGVTTETERSPFMSVDPAAPAAAFSSVQQLREILLDETKGMYERYAALFALR 692
+E G E SP+ SVDPA PA + V LR +LLDE++ +++RY A+FALR
Sbjct: 133 ------QEHG--EEPGSSPYRSVDPAPPAEE-TDVATLRAVLLDESRPLFDRYRAMFALR 183
Query: 693 NHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMVRHEAA 872
N GG DAV A+ D L A SAL RHE+ YVLGQ+Q++A + L+ LR E+PMVRHE A
Sbjct: 184 NLGGRDAVLALADGLRAGSALFRHEIGYVLGQMQDEACVPQLTAALRSRAENPMVRHECA 243
Query: 873 EALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFENFGKSFEF 1016
EALGSIA + L+ F +D E +V +SCEVAL M E+EN G F++
Sbjct: 244 EALGSIARPSCLETLRAFAQDEERVVRESCEVALDMYEYEN-GPQFQY 290
>sp|Q9BU89|DOHH_HUMAN Deoxyhypusine hydroxylase OS=Homo sapiens GN=DOHH PE=1
SV=1
Length = 302
Score = 258 bits (659), Expect = 5e-068
Identities = 150/290 (51%), Positives = 186/290 (64%), Gaps = 11/290 (3%)
Frame = +3
Query: 147 ERLVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAHEAAFALGQMQDAEAV 326
+ LVD QP+ RFRALF+LR L GPG + A D S LL HE A+ LGQMQDA A+
Sbjct: 12 QTLVDPKQPLQARFRALFTLRGLGGPGAIAWISQAFDDDSALLKHELAYCLGQMQDARAI 71
Query: 327 PALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCELALKRIE 506
P L VL D P+VRHEA EALGAIG EILK+ DP EV ETC+LA++R+E
Sbjct: 72 PMLVDVLQDTRQEPMVRHEAGEALGAIGDPEVLEILKQ-YSSDPVIEVAETCQLAVRRLE 130
Query: 507 ELSNVDAEKELGVTTETERSPFMSVDPAAPAAAFSSVQQLREILLDETKGMYERYAALFA 686
L E G P++SVDPA PA V +LRE LLDE++ ++ERY A+FA
Sbjct: 131 WLQQHGGEPAAG--------PYLSVDPAPPAEE-RDVGRLREALLDESRPLFERYRAMFA 181
Query: 687 LRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMVRHE 866
LRN GGE+A A+ + L SAL RHEV YVLGQLQ++AA+ L+ L E+PMVRHE
Sbjct: 182 LRNAGGEEAALALAEGLHCGSALFRHEVGYVLGQLQHEAAVPQLAAALARCTENPMVRHE 241
Query: 867 AAEALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFENFGKSFEF 1016
AEALG+IA +A LQ DPE +V +SCEVAL M E E G++F++
Sbjct: 242 CAEALGAIARPACLAALQAHADDPERVVRESCEVALDMYEHET-GRAFQY 290
>sp|Q99LN9|DOHH_MOUSE Deoxyhypusine hydroxylase OS=Mus musculus GN=Dohh PE=2
SV=2
Length = 302
Score = 257 bits (655), Expect = 2e-067
Identities = 147/283 (51%), Positives = 182/283 (64%), Gaps = 13/283 (4%)
Frame = +3
Query: 153 LVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAHEAAFALGQMQDAEAVPA 332
LVD QP+ RFRALF+LR L GP + + DSS LL HE A+ LGQM+DA A+P
Sbjct: 14 LVDPKQPLQARFRALFTLRGLGGPDAISWISRGFEDSSALLKHELAYCLGQMRDARAIPV 73
Query: 333 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEI--LKKSLVLDPAQEVRETCELALKRIE 506
L VL D S P+VRHEA EALGAI GN E+ L K DP EV ETC+LA+ R+E
Sbjct: 74 LADVLQDTSQEPMVRHEAGEALGAI---GNPEVLGLLKQYSTDPVVEVAETCQLAVGRLE 130
Query: 507 ELSNVDAEKELGVTTETERSPFMSVDPAAPAAAFSSVQQLREILLDETKGMYERYAALFA 686
L E T P++SVDPA PAA V +LRE LLDE + ++ERY A+FA
Sbjct: 131 WLQQHPGE-------ATCAGPYLSVDPAPPAAE-QDVGRLREALLDEARPLFERYRAMFA 182
Query: 687 LRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMVRHE 866
LRN GG++A A+ + L SAL RHEV YVLGQLQ++AA+ L+ L E PMVRHE
Sbjct: 183 LRNVGGKEAALALAEGLQCGSALFRHEVGYVLGQLQHEAAVPGLAATLARTTESPMVRHE 242
Query: 867 AAEALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFEN 995
AEALG+IA +A L+E + DPE +V +SCEVAL M E+E+
Sbjct: 243 CAEALGAIARPACLAALREHIEDPEQVVRESCEVALDMYEYES 285
>sp|Q7ZUX6|DOHH_DANRE Deoxyhypusine hydroxylase OS=Danio rerio GN=dohh PE=2
SV=1
Length = 305
Score = 256 bits (653), Expect = 3e-067
Identities = 144/281 (51%), Positives = 188/281 (66%), Gaps = 6/281 (2%)
Frame = +3
Query: 153 LVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAHEAAFALGQMQDAEAVPA 332
LV+ Q ++ RFRALF+LRNL G + A D S LL HE A+ LGQMQD A+P
Sbjct: 14 LVNTKQDLTTRFRALFTLRNLGGAEAVKWISEAFVDESALLKHELAYCLGQMQDESAIPT 73
Query: 333 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCELALKRIEEL 512
LE+VL D + P+VRHEA EALGAIG E+LKK DP EV ETC+LA+KR+E L
Sbjct: 74 LEAVLKDTNQEPMVRHEAGEALGAIGNPKVLELLKK-YAEDPVIEVAETCQLAVKRLEWL 132
Query: 513 SNVDAEKELGVTTETERSPFMSVDPAAPAAAFSSVQQLREILLDETKGMYERYAALFALR 692
N + + G T+ +P+ SVDPA PA SV +LR LLDET +++RY A+FALR
Sbjct: 133 MNGGEQTKDG----TDENPYCSVDPAPPAQR-KSVPELRTQLLDETLPLFDRYRAMFALR 187
Query: 693 NHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMVRHEAA 872
N G E+AV A+ D L +SAL RHE+ YVLGQ+Q++A++ L L ++E+ MVRHE A
Sbjct: 188 NLGTEEAVLALGDGLQCSSALFRHEIGYVLGQIQHEASIPQLQAALEKMDENAMVRHECA 247
Query: 873 EALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFEN 995
EALGSI E + +L+ + +D E +V +SCEVAL MLE+EN
Sbjct: 248 EALGSIGKEPCVQILERYRKDQERVVKESCEVALDMLEYEN 288
>sp|Q66KT3|DOHH_XENLA Deoxyhypusine hydroxylase OS=Xenopus laevis GN=dohh PE=2
SV=1
Length = 303
Score = 243 bits (618), Expect = 3e-063
Identities = 141/288 (48%), Positives = 182/288 (63%), Gaps = 12/288 (4%)
Frame = +3
Query: 141 LCERLVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAHEAAFALGQMQDAE 320
L + L+D +P+ RFRALF+LRNL G + + +D S LL HE A+ LGQM+D
Sbjct: 12 LGQLLIDPGKPLPLRFRALFTLRNLGGAEAIDCIGRGFQDESALLKHELAYCLGQMKDRR 71
Query: 321 AVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCELALKR 500
A+P L+ VL D P+VRHEA EALGAIG E+L++ DP EV ETC+LA+ R
Sbjct: 72 ALPVLKQVLQDRQQEPMVRHEAGEALGAIGDPEVLELLRE-YAQDPVIEVAETCQLAVSR 130
Query: 501 IEEL-SNVDAEKELGVTTETERSPFMSVDPAAPAAAFSSVQQLREILLDETKGMYERYAA 677
IE L N D+ + +P++SVDPA PA V LR LLDET ++ RY A
Sbjct: 131 IEWLQKNPDS---------PDTNPYLSVDPAPPAEE-KDVPTLRATLLDETCPLFHRYRA 180
Query: 678 LFALRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMV 857
+FALRN GGE+AV A+ D L +L RHE+ YVLGQ+Q+KAA+ LS L E+PMV
Sbjct: 181 MFALRNIGGEEAVLALADGLQIGGSLFRHEIGYVLGQMQHKAAVPGLSAALERFEENPMV 240
Query: 858 RHEAAEALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFENFG 1001
RHE AEALGSIA E + L+ + D E +V +SCEVAL M ++EN G
Sbjct: 241 RHECAEALGSIAHEDCLKALRAHVGDGERVVRESCEVALDMHDYENSG 288
Score = 115 bits (287), Expect = 7e-025
Identities = 57/131 (43%), Positives = 89/131 (67%)
Frame = +3
Query: 597 AAAFSSVQQLREILLDETKGMYERYAALFALRNHGGEDAVSAIVDSLSANSALLRHEVAY 776
A+ S V L ++L+D K + R+ ALF LRN GG +A+ I SALL+HE+AY
Sbjct: 3 ASLSSEVHSLGQLLIDPGKPLPLRFRALFTLRNLGGAEAIDCIGRGFQDESALLKHELAY 62
Query: 777 VLGQLQNKAALATLSKILRDVNEHPMVRHEAAEALGSIADEQSIALLQEFLRDPEPIVSQ 956
LGQ++++ AL L ++L+D + PMVRHEA EALG+I D + + LL+E+ +DP V++
Sbjct: 63 CLGQMKDRRALPVLKQVLQDRQQEPMVRHEAGEALGAIGDPEVLELLREYAQDPVIEVAE 122
Query: 957 SCEVALSMLEF 989
+C++A+S +E+
Sbjct: 123 TCQLAVSRIEW 133
>sp|Q9V9U4|DOHH_DROME Deoxyhypusine hydroxylase OS=Drosophila melanogaster
GN=nero PE=2 SV=1
Length = 302
Score = 225 bits (573), Expect = 5e-058
Identities = 128/281 (45%), Positives = 177/281 (62%), Gaps = 9/281 (3%)
Frame = +3
Query: 153 LVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAHEAAFALGQMQDAEAVPA 332
L ++ +P+ ERFRALF+L+N+ G A+ A D S LL HE A+ LGQMQDA+A+
Sbjct: 14 LNNKERPLKERFRALFTLKNIGGGAAIEAISKAFDDDSALLKHELAYCLGQMQDAQALDI 73
Query: 333 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCELALKRIEEL 512
L VL D + P+VRHEAAEA+GAIG IL++ DP EV ETC +AL R+ L
Sbjct: 74 LTKVLKDTTQEPMVRHEAAEAMGAIGHPDVLPILEE-YKQDPVVEVAETCAIALDRVRWL 132
Query: 513 SNVDAEKELGVTTETERSPFMSVDPAAPAAAFSSVQQLREILLDETKGMYERYAALFALR 692
+ G + + +P+ SVDP+ P A SV +L+ I LD + +++RY A+F+LR
Sbjct: 133 QS-------GQKVD-DSNPYASVDPSPPTAGDKSVTELKAIYLDAQQSLFDRYRAMFSLR 184
Query: 693 NHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMVRHEAA 872
N E++V AI + L +SAL RHEVA+VLGQLQ ++ L + L D E+ MVRHE A
Sbjct: 185 NLRTEESVLAIAEGLKDSSALFRHEVAFVLGQLQEPCSIPFLQENLEDRLENEMVRHECA 244
Query: 873 EALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFEN 995
EALG+IA E I +L + D + +V +SC +AL M E+EN
Sbjct: 245 EALGAIATEDCIQILNRYAEDDKRVVKESCVIALDMCEYEN 285
>sp|Q297S2|DOHH_DROPS Deoxyhypusine hydroxylase OS=Drosophila pseudoobscura
pseudoobscura GN=nero PE=3 SV=1
Length = 302
Score = 222 bits (565), Expect = 4e-057
Identities = 126/281 (44%), Positives = 175/281 (62%), Gaps = 9/281 (3%)
Frame = +3
Query: 153 LVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAHEAAFALGQMQDAEAVPA 332
L ++ +P+ ERFRALF+L+N+ G +A+ A D S LL HE A+ LGQMQD A+
Sbjct: 14 LNNKDRPLKERFRALFTLKNIGGKTAIDAISKAFDDDSALLKHELAYCLGQMQDPTALEI 73
Query: 333 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCELALKRIEEL 512
L VL D + P+VRHEAAEA+GAIG A IL++ DP EV ETC +AL R+ L
Sbjct: 74 LTKVLKDTTQEPMVRHEAAEAMGAIGHADVLAILEE-YKKDPVVEVAETCAIALDRVRWL 132
Query: 513 SNVDAEKELGVTTETERSPFMSVDPAAPAAAFSSVQQLREILLDETKGMYERYAALFALR 692
+ + +P+ SVDP+ P A SV +L+ I LD + +++RY A+F+LR
Sbjct: 133 QSGQ--------QVADNNPYASVDPSPPTAGDKSVAELKAIYLDAKQTLFDRYRAMFSLR 184
Query: 693 NHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMVRHEAA 872
N E++V AI + L +SAL RHEVA+VLGQLQ ++ L + L D E+ MVRHE A
Sbjct: 185 NLCTEESVLAIAEGLKDSSALFRHEVAFVLGQLQEPCSIPYLQENLEDHKENEMVRHECA 244
Query: 873 EALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFEN 995
EALG+IA + I +L + D + +V +SC +AL M E+EN
Sbjct: 245 EALGAIATDDCIQILTRYADDEKRVVKESCVIALDMCEYEN 285
>sp|Q59Z14|DOHH_CANAL Deoxyhypusine hydroxylase OS=Candida albicans GN=LIA1 PE=3
SV=1
Length = 318
Score = 212 bits (539), Expect = 4e-054
Identities = 124/285 (43%), Positives = 178/285 (62%), Gaps = 16/285 (5%)
Frame = +3
Query: 174 ISERFRALFSLRNL------KGPGPRNALILAS--RDSSNLLAHEAAFALGQMQDAEAVP 329
++ RFRALF+L+++ K + +A D S LL HE A+ LGQ +D A P
Sbjct: 29 LANRFRALFNLKSVGSEDSDKERAHKAIKYIAECFNDDSELLKHEVAYVLGQTKDLYAAP 88
Query: 330 ALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCELALKRIEE 509
L VL + + +VRHEAAEALGA+G + +L+K DP E+R+TCELA++RI
Sbjct: 89 YLREVLENDNQQCMVRHEAAEALGALGDKESLPLLEKYFKEDPLLEIRQTCELAIERIHW 148
Query: 510 LSNVDAEKELGVTTETERSPFMSVDPAAPAA---AFSSVQQLREILLDETKGMYERYAAL 680
++ A+ E+ E+S + S+DPA P A + S V++L+EIL D+ K ++ERY A+
Sbjct: 149 ENSEKAKNEV-----LEKSLYTSIDPAPPLATNDSTSKVEKLKEILNDQDKPLFERYRAM 203
Query: 681 FALRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMVR 860
F LR+ G ++A A+ SAL +HE+AYV GQ+ N + +L K+L+D +E MVR
Sbjct: 204 FRLRDIGTDEACLALASGFDDPSALFKHEIAYVFGQMCNPVTVPSLIKVLKDESEAGMVR 263
Query: 861 HEAAEALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFEN 995
HEAAEALGSIA ++ + +LQ FL D EP+V S VAL M E+EN
Sbjct: 264 HEAAEALGSIATDECLPVLQSFLNDSEPVVRDSAIVALDMYEYEN 308
>sp|Q6CHJ7|DOHH_YARLI Deoxyhypusine hydroxylase OS=Yarrowia lipolytica GN=LIA1
PE=3 SV=1
Length = 308
Score = 212 bits (539), Expect = 4e-054
Identities = 121/289 (41%), Positives = 182/289 (62%), Gaps = 15/289 (5%)
Frame = +3
Query: 159 DQSQPISERFRALFSLRNLKGPGPRNALILAS---RDSSNLLAHEAAFALGQMQDAEAVP 329
D ++ RFRALFSL+++ G A+ + + +D S LL HE A+ LGQ ++ AV
Sbjct: 17 DGQTALALRFRALFSLKDMGEKGDNGAIDVIAEGFKDDSELLKHELAYVLGQTKNFHAVK 76
Query: 330 ALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCELALKRIEE 509
L+ VL D + +VRHEAAEALGA+G G+ +L++ DP + +RETCELAL+RI +
Sbjct: 77 PLQGVLADTNQQAMVRHEAAEALGALGDKGSVAMLQEYFENDPLEVIRETCELALERI-K 135
Query: 510 LSNVDAEKELGVTTETERSPFMSVDPAAP-------AAAFSSVQQLREILLDETKGMYER 668
N +A K T ++S + S+DPA P + ++V++L++ L+D+++ ++ R
Sbjct: 136 WENSEAAK----TETLQKSAYTSIDPAPPLPTDQAEGSDKATVEKLQKTLMDKSQSLFHR 191
Query: 669 YAALFALRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEH 848
Y A+F LR+ G EDAV A+ +SAL RHE+AYV GQ+ + A++ L K+L E
Sbjct: 192 YRAMFRLRDIGTEDAVLALATGFDDSSALFRHEIAYVFGQMSDPASVPALIKVLGKTEEE 251
Query: 849 PMVRHEAAEALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFEN 995
MVRHEAAEALGSIA + + +L++F D + +V +S VAL M E+EN
Sbjct: 252 GMVRHEAAEALGSIATDDVLPILKKFAEDKDQVVRESAIVALDMYEYEN 300
>sp|Q9P6K9|DOHH_SCHPO Deoxyhypusine hydroxylase OS=Schizosaccharomyces pombe
GN=lia1 PE=2 SV=1
Length = 318
Score = 210 bits (534), Expect = 2e-053
Identities = 125/311 (40%), Positives = 184/311 (59%), Gaps = 14/311 (4%)
Frame = +3
Query: 93 SASSTENGVVNDVEKFLCERLVDQSQPISERFRALFSLRNLKGPGPR---NALILASRDS 263
S+ V++++E+ L +D+S P+S R+RALFSL L G + +A+ A D
Sbjct: 2 SSEPVPQAVIDELERVLVN--LDKSNPLSFRYRALFSLNALAKKGDKRAVDAIYKAFIDD 59
Query: 264 SNLLAHEAAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKS 443
S LL HE A+ +GQ AV L +++ND+ +VRHEAAEALGA+G + +L+K
Sbjct: 60 SELLKHEMAYVMGQSGQQYAVQPLINIVNDLDQQVMVRHEAAEALGALGFTESLPVLEKY 119
Query: 444 LVLDPAQEVRETCELALKRIEELSNVDAEKELGVTTETERSPFMSVDPAAPAA-----AF 608
DP +RETCELA+ RI+ + +D E +T S VDPA P
Sbjct: 120 YKEDPLAPIRETCELAIARIQWKNGLDKNNE-KITPSMYDS---VVDPAPPMPDHEQDVK 175
Query: 609 SSVQQLREILLDETKGMYERYAALFALRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQ 788
S V +LR ++D+ ++ RY +F LRN G E+AV A+ D S L RHE+A+V GQ
Sbjct: 176 SEVAKLRSEIVDQNLPLFYRYRVMFRLRNIGNEEAVLALTDGFKDPSPLFRHEIAFVFGQ 235
Query: 789 LQNKAALATLSKILRDVNEHPMVRHEAAEALGSIADEQSIALLQEFLRDPEPIVSQSCEV 968
+ A++ L K+L + E PMVRHEAAEALG IA+++ + +L++F +D +V++SC V
Sbjct: 236 MIAPASVPALIKVLENTEEVPMVRHEAAEALGGIANDECLPVLKKFSKDDVRVVAESCIV 295
Query: 969 ALSMLEFENFG 1001
AL M+E+E G
Sbjct: 296 ALDMIEYEKSG 306
>sp|Q6FUV3|DOHH_CANGA Deoxyhypusine hydroxylase OS=Candida glabrata GN=LIA1 PE=3
SV=1
Length = 322
Score = 199 bits (504), Expect = 5e-050
Identities = 116/285 (40%), Positives = 172/285 (60%), Gaps = 16/285 (5%)
Frame = +3
Query: 174 ISERFRALFSLRNLKGPGPRNALILASR---------DSSNLLAHEAAFALGQMQDAEAV 326
++ RFRALF+L+ N D+S LL HE A+ LGQ ++ +A
Sbjct: 34 LANRFRALFNLKTAASEFEANPSDAEKAVQYMGETFGDNSELLKHEVAYVLGQTKNLKAA 93
Query: 327 PALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCELALKRIE 506
P L + D++ P+VRHEAAEALGA+G + E L+K L DP VRETCELA+ RI
Sbjct: 94 PLLRKTMLDLAQQPMVRHEAAEALGALGDKDSLEDLEKCLKNDPHVAVRETCELAIARIN 153
Query: 507 ELSNVDAEKELGVTTETERSPFMSVDPAAPAAAFS--SVQQLREILLDETKGMYERYAAL 680
+ KE ++S + S+DPA P A +++L+++L D+ K ++ RY A+
Sbjct: 154 WQHSDAPTKE-----SLQQSLYSSIDPAPPLALEKEYDLEELKKLLNDQEKPLFLRYRAM 208
Query: 681 FALRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMVR 860
F LR+ G ++AV A+ + SAL +HE+AYV GQ+ + AA+ +L+++L E PMVR
Sbjct: 209 FRLRDIGTDEAVLALASGFNDPSALFKHEIAYVFGQMGSTAAVPSLTEVLGRKEEAPMVR 268
Query: 861 HEAAEALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFEN 995
HEAAEALG+IA E ++ +L+++L D +V +S VAL M E+EN
Sbjct: 269 HEAAEALGAIASEDALPILKQYLNDEVDVVRESAIVALDMWEYEN 313
>sp|Q6CV81|DOHH_KLULA Deoxyhypusine hydroxylase OS=Kluyveromyces lactis GN=LIA1
PE=3 SV=1
Length = 322
Score = 198 bits (501), Expect = 1e-049
Identities = 116/286 (40%), Positives = 169/286 (59%), Gaps = 16/286 (5%)
Frame = +3
Query: 171 PISERFRALFSLRNLK---GPGPRNA------LILASRDSSNLLAHEAAFALGQMQDAEA 323
P++ RFRALF+L+ P +A L A D S LL HE A+ LGQ ++
Sbjct: 33 PLANRFRALFNLKGHAEEFASKPEDALKATQYLAEAFGDESELLKHEVAYVLGQTKNMAG 92
Query: 324 VPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCELALKRI 503
P L VL D +VRHEAAEALGA+ + +IL+K DP E+R+TCELA+ RI
Sbjct: 93 APLLRDVLADDKQQCMVRHEAAEALGALNDVDSLDILEKYFKEDPLLEIRQTCELAIDRI 152
Query: 504 EELSNVDAEKELGVTTETERSPFMSVDPAAPAAAFS--SVQQLREILLDETKGMYERYAA 677
+ ++ + +E + S + S+DPA P + +Q+L++IL D+ + ++ERY A
Sbjct: 153 KWETSEEGRRE-----ALQESLYSSIDPAPPFSLEKDYKIQELKDILNDQNRPLFERYRA 207
Query: 678 LFALRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMV 857
+F LR+ G ++A A+ SAL +HE+AYV GQ+ N + L ++L E PMV
Sbjct: 208 MFRLRDIGNDEACLALASGFDDPSALFKHEIAYVFGQICNPVVVPHLKEVLARPEEAPMV 267
Query: 858 RHEAAEALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFEN 995
RHEAAEALGSIA + + +L+E L+D + +V +S VAL M E+EN
Sbjct: 268 RHEAAEALGSIATDDVLPVLKEHLKDSDSVVRESAIVALDMYEYEN 313
>sp|P47120|DOHH_YEAST Deoxyhypusine hydroxylase OS=Saccharomyces cerevisiae
GN=LIA1 PE=1 SV=1
Length = 325
Score = 196 bits (497), Expect = 3e-049
Identities = 113/286 (39%), Positives = 173/286 (60%), Gaps = 17/286 (5%)
Frame = +3
Query: 174 ISERFRALFSLRNL------KGPGPRNALILAS----RDSSNLLAHEAAFALGQMQDAEA 323
++ RFRALF+L+ + K + A+ + D S LL HE A+ LGQ ++ +A
Sbjct: 34 LANRFRALFNLKTVAEEFATKPEEAKKAIEYIAESFVNDKSELLKHEVAYVLGQTKNLDA 93
Query: 324 VPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCELALKRI 503
P L V+ D + P+VRHEAAEALGA+G + + L K+ DP VRETCELA+ RI
Sbjct: 94 APTLRHVMLDQNQEPMVRHEAAEALGALGDKDSLDDLNKAAKEDPHVAVRETCELAINRI 153
Query: 504 EELSNVDAEKELGVTTETERSPFMSVDPA--APAAAFSSVQQLREILLDETKGMYERYAA 677
+KE ++S + S+DPA P +++ +L+ +L D + +++RY A
Sbjct: 154 NWTHGGAKDKE-----NLQQSLYSSIDPAPPLPLEKDATIPELQALLNDPKQPLFQRYRA 208
Query: 678 LFALRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMV 857
+F LR+ G ++A+ A+ SA S+L +HE+AYV GQ+ + AA+ +L ++L E PMV
Sbjct: 209 MFRLRDIGTDEAILALATGFSAESSLFKHEIAYVFGQIGSPAAVPSLIEVLGRKEEAPMV 268
Query: 858 RHEAAEALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFEN 995
RHEAAEALG+IA + + +L+ +L D +V +SC VAL M ++EN
Sbjct: 269 RHEAAEALGAIASPEVVDVLKSYLNDEVDVVRESCIVALDMYDYEN 314
>sp|Q752Z8|DOHH_ASHGO Deoxyhypusine hydroxylase OS=Ashbya gossypii GN=LIA1 PE=3
SV=2
Length = 322
Score = 184 bits (467), Expect = 1e-045
Identities = 113/286 (39%), Positives = 170/286 (59%), Gaps = 18/286 (6%)
Frame = +3
Query: 174 ISERFRALFSLRNLK---GPGPRNA------LILASRDSSNLLAHEAAFALGQMQDAEAV 326
++ RFRALF+L+ + P A + A DSS LL HE A+ LGQ +
Sbjct: 34 LTNRFRALFNLKCVAEEFAQRPEEAQRAVEYICEAFADSSELLKHEVAYVLGQTGNLACA 93
Query: 327 PALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLVLDPAQEVRETCELALKRIE 506
L V+ D + +VRHEA+EALGA+G A + L++S DP++EVR+T ELA++RI
Sbjct: 94 ATLREVMLDHAQQCMVRHEASEALGALGDAASLGALERSRREDPSEEVRQTSELAIERIR 153
Query: 507 ELSNVDAEKELGVTTETERSPFMSVDPAAPAAAFS---SVQQLREILLDETKGMYERYAA 677
++ A T + ++S + SVDP APA + V QL+ +L D+ ++ERY A
Sbjct: 154 WQASGAA-----ATEQLQQSLYSSVDP-APALSLEKDYDVPQLQALLNDQRAPLFERYRA 207
Query: 678 LFALRNHGGEDAVSAIVDSLSANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMV 857
+F LR+ G ++A A+ SAL +HE+AYV GQ+ N + L ++L+ +E PMV
Sbjct: 208 MFRLRDIGSDEACYALASGFDDPSALFKHEIAYVFGQIGNPCVVPHLQEVLKREHEAPMV 267
Query: 858 RHEAAEALGSIADEQSIALLQEFLRDPEPIVSQSCEVALSMLEFEN 995
RHEAAEALGSIA + + +L+ L+D + +V +S +AL M ++EN
Sbjct: 268 RHEAAEALGSIATDDVLPVLKRHLQDKDEVVRESAAIALDMYDYEN 313
>sp|Q5PPJ4|DOHH_RAT Deoxyhypusine hydroxylase OS=Rattus norvegicus GN=Dohh PE=2
SV=1
Length = 302
Score = 159 bits (401), Expect = 4e-038
Identities = 82/150 (54%), Positives = 109/150 (72%), Gaps = 2/150 (1%)
Frame = +3
Query: 567 PFMSVDPAAPAAAFSSVQQLREILLDETKGMYERYAALFALRNHGGEDAVSAIVDSLSAN 746
P++SVDPA PAA V +LRE LLDE + ++ERY A+FALRN GG++A A+ + L
Sbjct: 144 PYLSVDPAPPAAE-GDVGRLRETLLDEAQPLFERYRAMFALRNVGGKEAALALAEGLKCG 202
Query: 747 SALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMVRHEAAEALGSIADEQSIALLQEF 926
SAL RHEV YVLGQLQ++AA++ L+ L E PMVRHE AEALG+IA +A L+E+
Sbjct: 203 SALFRHEVGYVLGQLQHEAAVSELAATLARTTESPMVRHECAEALGAIARPACLAALREY 262
Query: 927 LRDPEPIVSQSCEVALSMLEFENFGKSFEF 1016
+ DPE +V +SCEVAL M E+EN G+ F++
Sbjct: 263 ITDPERVVRESCEVALDMYEYEN-GQDFQY 291
>sp|Q0VC53|DOHH_BOVIN Deoxyhypusine hydroxylase OS=Bos taurus GN=DOHH PE=1 SV=1
Length = 303
Score = 149 bits (374), Expect = 6e-035
Identities = 76/152 (50%), Positives = 106/152 (69%), Gaps = 2/152 (1%)
Frame = +3
Query: 561 RSPFMSVDPAAPAAAFSSVQQLREILLDETKGMYERYAALFALRNHGGEDAVSAIVDSLS 740
R P++SVDPA PA + QLRE LLDE + +++RY A+FALR+ GG++A A+ + L
Sbjct: 142 RGPYLSVDPAPPAEE-RDLGQLREALLDEARPLFDRYRAMFALRDAGGKEAALALAEGLR 200
Query: 741 ANSALLRHEVAYVLGQLQNKAALATLSKILRDVNEHPMVRHEAAEALGSIADEQSIALLQ 920
SAL RHE+ YVLGQ+Q++AA+ L+ L E+PMVRHE AEALG+IA +A L+
Sbjct: 201 CGSALFRHEIGYVLGQMQHEAAVPQLAAALAQPTENPMVRHECAEALGAIARPACLAALR 260
Query: 921 EFLRDPEPIVSQSCEVALSMLEFENFGKSFEF 1016
+ DPE +V +SCEVAL M E+E G +F++
Sbjct: 261 AHVADPERVVRESCEVALDMYEYET-GSTFQY 291
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0
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