BLASTX 7.6.2
Query= UN17046 /QuerySize=2096
(2095 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8GWC3|PR1A2_ARATH PRA1 family protein A2 OS=Arabidopsis thal... 406 5e-112
sp|Q8W115|PR1A3_ARATH PRA1 family protein A3 OS=Arabidopsis thal... 372 9e-102
sp|Q9ASX2|TRNH1_ARATH Tropinone reductase homolog At1g07440 OS=A... 343 3e-093
sp|P50165|TRNH_DATST Tropinone reductase homolog OS=Datura stram... 309 5e-083
sp|P50162|TRN1_DATST Tropinone reductase 1 OS=Datura stramonium ... 298 1e-079
sp|Q9LZM7|PR1A1_ARATH PRA1 family protein A1 OS=Arabidopsis thal... 287 2e-076
sp|P50164|TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamus niger G... 287 4e-076
sp|P50163|TRN2_DATST Tropinone reductase 2 OS=Datura stramonium ... 281 2e-074
sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member ... 163 8e-039
sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 ... 155 2e-036
sp|P50199|GNO_GLUOX Gluconate 5-dehydrogenase OS=Gluconobacter o... 153 6e-036
sp|Q99LB2|DHRS4_MOUSE Dehydrogenase/reductase SDR family member ... 153 8e-036
sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member ... 151 2e-035
sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member ... 151 2e-035
sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member ... 150 4e-035
sp|Q8WNV7|DHRS4_PIG Dehydrogenase/reductase SDR family member 4 ... 145 2e-033
sp|P0A9Q0|IDNO_ECOL6 Gluconate 5-dehydrogenase OS=Escherichia co... 131 3e-029
sp|P0A9P9|IDNO_ECOLI Gluconate 5-dehydrogenase OS=Escherichia co... 131 3e-029
sp|P39640|BACC_BACSU Bacilysin biosynthesis oxidoreductase BacC ... 127 5e-028
sp|Q8KWT4|BACC2_BACSU Bacilysin biosynthesis oxidoreductase BacC... 126 8e-028
>sp|Q8GWC3|PR1A2_ARATH PRA1 family protein A2 OS=Arabidopsis thaliana GN=PRA1A2
PE=2 SV=1
Length = 209
Score = 406 bits (1041), Expect = 5e-112
Identities = 196/209 (93%), Positives = 203/209 (97%)
Frame = +1
Query: 187 MDWDNVAAEDVIEALREVEWSTPPRSFGEFFSRFAFPRSFSKWKSRLKCNLYYYRTNYFI 366
MDWDNVAAEDVIEALREVEWSTPPRSFGEFFSRFAFPRSFSKWKSRLKCNLYYYRTNYFI
Sbjct: 1 MDWDNVAAEDVIEALREVEWSTPPRSFGEFFSRFAFPRSFSKWKSRLKCNLYYYRTNYFI 60
Query: 367 LVIFVLGLALITRPLAIVGAAFTALSIAFLNDSFAATFNEKCIRTIRLFSPHLAAKMRPP 546
LVIFVLGLAL+TRPLA+VGAA TALSIAFLNDSFAA+FNEK IRTIR FSPH+AAKMRPP
Sbjct: 61 LVIFVLGLALVTRPLALVGAALTALSIAFLNDSFAASFNEKFIRTIRHFSPHMAAKMRPP 120
Query: 547 HMPVIRGRSAARKTVYVCGKPRWVFVVIFLTASLVMWFSSCGLLWVLYALLTSLIVVIVH 726
HMPVIRGRS ARKTVYVCGKPRWVFV+ FLTASLVMWFSSCGLLWVLYALLTSL V+IVH
Sbjct: 121 HMPVIRGRSTARKTVYVCGKPRWVFVITFLTASLVMWFSSCGLLWVLYALLTSLAVIIVH 180
Query: 727 ASVRTPNLKARLNTFREEFRAVWRNYSEL 813
AS+RTPNLKARLNTFREEFRAVWRNYSEL
Sbjct: 181 ASIRTPNLKARLNTFREEFRAVWRNYSEL 209
>sp|Q8W115|PR1A3_ARATH PRA1 family protein A3 OS=Arabidopsis thaliana GN=PRA1A3
PE=2 SV=1
Length = 209
Score = 372 bits (953), Expect = 9e-102
Identities = 178/209 (85%), Positives = 195/209 (93%)
Frame = +1
Query: 187 MDWDNVAAEDVIEALREVEWSTPPRSFGEFFSRFAFPRSFSKWKSRLKCNLYYYRTNYFI 366
MDWD+VAAEDVIEALREVEWS PRS EFFSRFAFPRSFSKW SRLKCNLYYYRTNYFI
Sbjct: 1 MDWDSVAAEDVIEALREVEWSASPRSLAEFFSRFAFPRSFSKWMSRLKCNLYYYRTNYFI 60
Query: 367 LVIFVLGLALITRPLAIVGAAFTALSIAFLNDSFAATFNEKCIRTIRLFSPHLAAKMRPP 546
L +FVLGLALITRPLAI+GAA TALS+AFLNDSFAATFNEK IRTIR FSPHLAAKMRPP
Sbjct: 61 LFVFVLGLALITRPLAILGAALTALSLAFLNDSFAATFNEKMIRTIRHFSPHLAAKMRPP 120
Query: 547 HMPVIRGRSAARKTVYVCGKPRWVFVVIFLTASLVMWFSSCGLLWVLYALLTSLIVVIVH 726
HMPVIRGRSA RKTVY+CG+PR VFV++ LTAS V+WF+SCGLLWVLYAL T+L+++++H
Sbjct: 121 HMPVIRGRSATRKTVYICGQPRLVFVLLGLTASFVLWFTSCGLLWVLYALTTALLMILLH 180
Query: 727 ASVRTPNLKARLNTFREEFRAVWRNYSEL 813
AS+RTPNLKARLNTFREEFRAVWRNYSEL
Sbjct: 181 ASLRTPNLKARLNTFREEFRAVWRNYSEL 209
>sp|Q9ASX2|TRNH1_ARATH Tropinone reductase homolog At1g07440 OS=Arabidopsis
thaliana GN=At1g07440 PE=1 SV=1
Length = 266
Score = 343 bits (879), Expect = 3e-093
Identities = 169/259 (65%), Positives = 204/259 (78%), Gaps = 1/259 (0%)
Frame = -2
Query: 2052 ENNKRWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLV 1873
E ++RWSL KT LVTGGT+GIG A+VEE A FGA +HTC+RN+ EL CL W+ G
Sbjct: 5 EQSQRWSLKAKTVLVTGGTKGIGHAIVEEFAGFGAVIHTCARNEYELNECLSKWQKKGFQ 64
Query: 1872 VTGSVCDASDRDQREKLIEEVSSAFSGKLNILINNVGTNIRKPTVEYTSEDYAKIMSINL 1693
VTGSVCDAS R +REKL++ VSS F GKL+ILINN+G KPT++YT+ED++ +S NL
Sbjct: 65 VTGSVCDASLRPEREKLMQTVSSMFGGKLDILINNLGAIRSKPTLDYTAEDFSFHISTNL 124
Query: 1692 ESAFHFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAG 1513
ESA+H SQ+AHPLLKASG G+I+F+SS+AG+V S GS+Y ATKGALNQL RNLACEWA
Sbjct: 125 ESAYHLSQLAHPLLKASGCGNIIFMSSIAGVVSASVGSIYSATKGALNQLARNLACEWAS 184
Query: 1512 DNIRTNCVAPWYIKTSLVKPLLEKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASY 1333
D IR N VAP I T L + + + + F++ V+SR PLGR GEPEEVSSLVAFLC+PAASY
Sbjct: 185 DGIRANAVAPAVIATPLAEAVYDDE-FKKVVISRKPLGRFGEPEEVSSLVAFLCMPAASY 243
Query: 1332 ITGQVISVDGGFTVNGFSY 1276
ITGQ I VDGG TVNGFSY
Sbjct: 244 ITGQTICVDGGLTVNGFSY 262
>sp|P50165|TRNH_DATST Tropinone reductase homolog OS=Datura stramonium PE=2
SV=1
Length = 268
Score = 309 bits (791), Expect = 5e-083
Identities = 149/258 (57%), Positives = 194/258 (75%), Gaps = 3/258 (1%)
Frame = -2
Query: 2046 NKRWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVT 1867
++RWSL G TALVTGGTRGIG A+VEELA FGA V+TCSR+Q++L CL+ W+ G V+
Sbjct: 10 DRRWSLRGMTALVTGGTRGIGYAIVEELANFGAEVYTCSRSQNDLDECLEKWRRKGFKVS 69
Query: 1866 GSVCDASDRDQREKLIEEVSSAFSGKLNILINNVGTNIRKPTVEYTSEDYAKIMSINLES 1687
G VCD S QR+ L+E V+S+F+GKLNILINN GT I K +T+EDY+ IM N E+
Sbjct: 70 GPVCDVSSISQRQTLMESVTSSFNGKLNILINNAGTTIPKEATNFTAEDYSIIMGTNFEA 129
Query: 1686 AFHFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDN 1507
+++ Q+AHPLLKASG SIVF SS AG++ + S+Y A+KGA+NQ+T++LACEWA D+
Sbjct: 130 SYNLCQLAHPLLKASGNASIVFNSSAAGVIAVPLSSIYAASKGAINQVTKSLACEWAKDS 189
Query: 1506 IRTNCVAPWYIKTSLVKPLLE---KKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAAS 1336
IR N VAPW I T +++ + +K E+++ R P+ R GEP EVSSLV +LCLP AS
Sbjct: 190 IRVNAVAPWIINTPIIEAACQVPSQKKNIESLIGRAPMKRAGEPSEVSSLVTYLCLPTAS 249
Query: 1335 YITGQVISVDGGFTVNGF 1282
YITGQ+I VDGG+TVNGF
Sbjct: 250 YITGQIICVDGGYTVNGF 267
>sp|P50162|TRN1_DATST Tropinone reductase 1 OS=Datura stramonium GN=TR1 PE=1
SV=1
Length = 273
Score = 298 bits (762), Expect = 1e-079
Identities = 146/263 (55%), Positives = 190/263 (72%), Gaps = 4/263 (1%)
Frame = -2
Query: 2061 LTMENNKRWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSN 1882
+ N RWSL G TALVTGG++GIG A+VEELA GA V+TCSRN+ EL CL+ W+
Sbjct: 9 MNCNNEGRWSLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREK 68
Query: 1881 GLVVTGSVCDASDRDQREKLIEEVSSAFSGKLNILINNVGTNIRKPTVEYTSEDYAKIMS 1702
GL V GSVCD R +R+KL++ V+ F GKLNIL+NN G I K ++T +DY IM
Sbjct: 69 GLNVEGSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMG 128
Query: 1701 INLESAFHFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACE 1522
N E+A+H SQIA+PLLKAS G+++F+SS+AG L S S+Y A+KGA+NQ+T++LACE
Sbjct: 129 TNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACE 188
Query: 1521 WAGDNIRTNCVAPWYIKTSLVKPLLEKKGFEEAVVS----RTPLGRVGEPEEVSSLVAFL 1354
WA DNIR N VAP I T LV+ ++K ++ + +TP+GR G+P+EVS+L+AFL
Sbjct: 189 WAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFL 248
Query: 1353 CLPAASYITGQVISVDGGFTVNG 1285
C PAASYITGQ+I DGGFT NG
Sbjct: 249 CFPAASYITGQIIWADGGFTANG 271
>sp|Q9LZM7|PR1A1_ARATH PRA1 family protein A1 OS=Arabidopsis thaliana GN=PRA1A1
PE=2 SV=1
Length = 209
Score = 287 bits (734), Expect = 2e-076
Identities = 133/209 (63%), Positives = 164/209 (78%)
Frame = +1
Query: 187 MDWDNVAAEDVIEALREVEWSTPPRSFGEFFSRFAFPRSFSKWKSRLKCNLYYYRTNYFI 366
MDW NV +D+ +ALREV+WS+PPR EFFSRF P+S KW SRLKCNLYYYRTNYFI
Sbjct: 1 MDWGNVTVDDLFDALREVDWSSPPRPPSEFFSRFTVPKSVPKWDSRLKCNLYYYRTNYFI 60
Query: 367 LVIFVLGLALITRPLAIVGAAFTALSIAFLNDSFAATFNEKCIRTIRLFSPHLAAKMRPP 546
+++ +LGL ++TRPLAI A TALS+AFLNDSFA +F+EK RT+R FSP LAAKMRPP
Sbjct: 61 MIVVILGLGVLTRPLAIFAALLTALSLAFLNDSFAGSFSEKATRTVRRFSPQLAAKMRPP 120
Query: 547 HMPVIRGRSAARKTVYVCGKPRWVFVVIFLTASLVMWFSSCGLLWVLYALLTSLIVVIVH 726
PV RGR ++++ ++VCG+PRWVFV+ S +W+ S GLL V ALL + + I+H
Sbjct: 121 LTPVTRGRPSSKRAIHVCGQPRWVFVLTCSLVSFALWYISSGLLRVSVALLIAHLATILH 180
Query: 727 ASVRTPNLKARLNTFREEFRAVWRNYSEL 813
AS+RTPNLKAR NTFREEFRAVWRNYSE+
Sbjct: 181 ASLRTPNLKARFNTFREEFRAVWRNYSEI 209
>sp|P50164|TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamus niger GN=TR2 PE=2
SV=1
Length = 260
Score = 287 bits (732), Expect = 4e-076
Identities = 146/255 (57%), Positives = 185/255 (72%), Gaps = 3/255 (1%)
Frame = -2
Query: 2040 RWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVTGS 1861
RW+L G TALVTGG+RGIG +VEELA GA+V+TCSRNQ EL CL W+S G V S
Sbjct: 4 RWNLEGCTALVTGGSRGIGYGIVEELANLGASVYTCSRNQKELDECLTQWRSKGFNVEAS 63
Query: 1860 VCDASDRDQREKLIEEVSSAFSGKLNILINNVGTNIRKPTVEYTSEDYAKIMSINLESAF 1681
VCD S R +RE+ ++ VS+ F GKLNIL+NN G I K +YT EDY+ IMSIN E+A+
Sbjct: 64 VCDLSSRSEREEFMKTVSNHFHGKLNILVNNAGIVIYKEAKDYTMEDYSHIMSINFEAAY 123
Query: 1680 HFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDNIR 1501
H S +AHP LKAS G++VFISS++G L +VYGATKGA++QLTR LA EWA DNIR
Sbjct: 124 HLSVLAHPFLKASERGNVVFISSISGASALPYEAVYGATKGAMDQLTRCLAFEWAKDNIR 183
Query: 1500 TNCVAPWYIKTSLVKPLL---EKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASYI 1330
N V P I TS+V+ + E+K + ++ R L R+GEP+E++++VAFLC PAASY+
Sbjct: 184 VNGVGPGVIATSMVEMTIQDPEQKENLDKLIDRCALRRMGEPKELAAVVAFLCFPAASYV 243
Query: 1329 TGQVISVDGGFTVNG 1285
TGQ+I VDGGF NG
Sbjct: 244 TGQIIYVDGGFMANG 258
>sp|P50163|TRN2_DATST Tropinone reductase 2 OS=Datura stramonium GN=TR2 PE=1
SV=1
Length = 260
Score = 281 bits (718), Expect = 2e-074
Identities = 144/254 (56%), Positives = 183/254 (72%), Gaps = 3/254 (1%)
Frame = -2
Query: 2040 RWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVTGS 1861
RW+L G TALVTGG+RGIG +VEELA GA+V+TCSRNQ EL CL W+S G V S
Sbjct: 4 RWNLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEAS 63
Query: 1860 VCDASDRDQREKLIEEVSSAFSGKLNILINNVGTNIRKPTVEYTSEDYAKIMSINLESAF 1681
VCD S R +R++L+ V++ F GKLNIL+NN G I K +YT EDY+ IMSIN E+A+
Sbjct: 64 VCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAY 123
Query: 1680 HFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDNIR 1501
H S +AHP LKAS G++VFISSV+G + + +VYGATKGA++QLTR LA EWA DNIR
Sbjct: 124 HLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIR 183
Query: 1500 TNCVAPWYIKTSLVKPLL---EKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASYI 1330
N V P I TSLV+ + E+K ++ R L R+GEP+E++++VAFLC PAASY+
Sbjct: 184 VNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPAASYV 243
Query: 1329 TGQVISVDGGFTVN 1288
TGQ+I VDGG N
Sbjct: 244 TGQIIYVDGGLMAN 257
>sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member 4
OS=Oryctolagus cuniculus GN=DHRS4 PE=1 SV=1
Length = 260
Score = 163 bits (410), Expect = 8e-039
Identities = 95/249 (38%), Positives = 141/249 (56%), Gaps = 2/249 (0%)
Frame = -2
Query: 2043 KRWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVTG 1864
+R LA K A+VT T GIG A+ LA+ GA V SR Q + + ++ GL VTG
Sbjct: 8 RRDPLANKVAIVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQAEGLSVTG 67
Query: 1863 SVCDASDRDQREKLIEEVSSAFSGKLNILINNVGTN-IRKPTVEYTSEDYAKIMSINLES 1687
+VC + RE+L+ + G ++IL++N N ++ T E + KI+ IN+++
Sbjct: 68 TVCHVGKAEDRERLVATALNLHGG-IDILVSNAAVNPFFGKLMDVTEEVWDKILDINVKA 126
Query: 1686 AFHFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDN 1507
++ P ++ G GS+V ++S+A S Y +K AL LT+NLA E A N
Sbjct: 127 MALMTKAVVPEMEKRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLTKNLALELAAQN 186
Query: 1506 IRTNCVAPWYIKTSLVKPLLEKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASYIT 1327
IR NC+AP IKTS K L E K EE ++ + + R+G+PEE + +V+FLC ASYIT
Sbjct: 187 IRVNCLAPGLIKTSFSKALWEDKAQEENIIQKLRIRRLGKPEECAGIVSFLCSEDASYIT 246
Query: 1326 GQVISVDGG 1300
G+ + V GG
Sbjct: 247 GETVVVAGG 255
>sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 OS=Rattus
norvegicus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 155 bits (390), Expect = 2e-036
Identities = 94/245 (38%), Positives = 131/245 (53%), Gaps = 2/245 (0%)
Frame = -2
Query: 2031 LAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVTGSVCD 1852
LA K ALVT T GIG A+ LA GA V SR Q + + + GL VTG VC
Sbjct: 12 LANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQGEGLSVTGVVCH 71
Query: 1851 ASDRDQREKLIEEVSSAFSGKLNILINNVGTN-IRKPTVEYTSEDYAKIMSINLESAFHF 1675
+ REKL+ G ++IL++N N ++ T E + K++SIN+ ++
Sbjct: 72 VGKAEDREKLVNMALKLHQG-IDILVSNAAVNPFFGNLMDVTEEVWNKVLSINVTASAMM 130
Query: 1674 SQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDNIRTN 1495
+ P ++ G GS+V +SSVAG V S Y +K AL LT+N A E A NIR N
Sbjct: 131 IKAVVPAMEKRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVN 190
Query: 1494 CVAPWYIKTSLVKPLLEKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASYITGQVI 1315
C+AP IKT L ++K EE + + R+G+PE+ +V+FLC ASYI G+ +
Sbjct: 191 CLAPGLIKTHFSSVLWKEKAREEMIKETMQIRRLGKPEDCVGIVSFLCSEDASYINGETV 250
Query: 1314 SVDGG 1300
V GG
Sbjct: 251 VVGGG 255
>sp|P50199|GNO_GLUOX Gluconate 5-dehydrogenase OS=Gluconobacter oxydans GN=gno
PE=1 SV=1
Length = 256
Score = 153 bits (385), Expect = 6e-036
Identities = 91/252 (36%), Positives = 141/252 (55%), Gaps = 5/252 (1%)
Frame = -2
Query: 2037 WSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVTGSV 1858
+SL+G ALVTG +RGIG + + LAR+GA V RN + L S +++ GL + +V
Sbjct: 7 FSLSGARALVTGASRGIGLTLAKGLARYGAEVVLNGRNAESLDSAQSGFEAEGLKASTAV 66
Query: 1857 CDASDRDQREKLIEEVSS--AFSGKLNILINNVGTNIRKPTVEYTSEDYAKIMSINLESA 1684
D +D+D +I+ V++ G ++ILINN G R P E++ +D+ +MS N+ +
Sbjct: 67 FDVTDQD---AVIDGVAAIERDMGPIDILINNAGIQRRAPLEEFSRKDWDDLMSTNVNAV 123
Query: 1683 FHFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDNI 1504
F Q + G G IV I SV + + Y ATKGA+ LT+ +A +W +
Sbjct: 124 FFVGQAVARHMIPRGRGKIVNICSVQSELARPGIAPYTATKGAVKNLTKGMATDWGRHGL 183
Query: 1503 RTNCVAPWYIKTSLVKPLLEKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASYITG 1324
+ N +AP Y T + + L+ + F + + RTP GR G+ EE+ FL A+S++ G
Sbjct: 184 QINGLAPGYFATEMTERLVADEEFTDWLCKRTPAGRWGQVEELVGAAVFLSSRASSFVNG 243
Query: 1323 QVISVDGGFTVN 1288
QV+ VDGG TV+
Sbjct: 244 QVLMVDGGITVS 255
>sp|Q99LB2|DHRS4_MOUSE Dehydrogenase/reductase SDR family member 4 OS=Mus
musculus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 153 bits (384), Expect = 8e-036
Identities = 93/249 (37%), Positives = 131/249 (52%), Gaps = 2/249 (0%)
Frame = -2
Query: 2043 KRWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVTG 1864
+R L+ K ALVT T GIG A+ LA GA V SR Q + + + GL VTG
Sbjct: 8 RRNPLSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSVTG 67
Query: 1863 SVCDASDRDQREKLIEEVSSAFSGKLNILINNVGTN-IRKPTVEYTSEDYAKIMSINLES 1687
VC + REKLI G ++IL++N N ++ T E + K++SIN+ +
Sbjct: 68 IVCHVGKAEDREKLITTALKRHRG-IDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTA 126
Query: 1686 AFHFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDN 1507
+ P ++ G GS+V + SVAG S Y +K AL LT+N A E A N
Sbjct: 127 TAMMIKAVVPEMEKRGGGSVVIVGSVAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKN 186
Query: 1506 IRTNCVAPWYIKTSLVKPLLEKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASYIT 1327
IR NC+AP IKT L E+K E+ + + R+G+PE+ + +V+FLC ASYI
Sbjct: 187 IRVNCLAPGLIKTRFSSVLWEEKAREDFIKEAMQIRRLGKPEDCAGIVSFLCSEDASYIN 246
Query: 1326 GQVISVDGG 1300
G+ + V GG
Sbjct: 247 GETVVVGGG 255
>sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member 4 OS=Homo
sapiens GN=DHRS4 PE=1 SV=2
Length = 260
Score = 151 bits (381), Expect = 2e-035
Identities = 93/249 (37%), Positives = 136/249 (54%), Gaps = 2/249 (0%)
Frame = -2
Query: 2043 KRWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVTG 1864
+R LA K ALVT T GIG A+ LA+ GA V SR Q + + + GL VTG
Sbjct: 8 RRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTG 67
Query: 1863 SVCDASDRDQREKLIEEVSSAFSGKLNILINNVGTN-IRKPTVEYTSEDYAKIMSINLES 1687
+VC + RE+L+ + G ++IL++N N ++ T E + K + IN+++
Sbjct: 68 TVCHVGKAEDRERLV-ATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKA 126
Query: 1686 AFHFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDN 1507
++ P ++ G GS+V +SS+A S Y +K AL LT+ LA E A N
Sbjct: 127 PALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRN 186
Query: 1506 IRTNCVAPWYIKTSLVKPLLEKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASYIT 1327
IR NC+AP IKTS + L K EE++ + R+GEPE+ + +V+FLC ASYIT
Sbjct: 187 IRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYIT 246
Query: 1326 GQVISVDGG 1300
G+ + V GG
Sbjct: 247 GETVVVGGG 255
>sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member 4 OS=Pongo
abelii GN=DHRS4 PE=2 SV=2
Length = 260
Score = 151 bits (381), Expect = 2e-035
Identities = 93/249 (37%), Positives = 136/249 (54%), Gaps = 2/249 (0%)
Frame = -2
Query: 2043 KRWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVTG 1864
+R LA K ALVT T GIG A+ LA+ GA V SR Q + + + GL VTG
Sbjct: 8 RRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTG 67
Query: 1863 SVCDASDRDQREKLIEEVSSAFSGKLNILINNVGTN-IRKPTVEYTSEDYAKIMSINLES 1687
+VC + RE+L+ + G ++IL++N N ++ T E + K + IN+++
Sbjct: 68 TVCHVGKAEDRERLV-ATAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKA 126
Query: 1686 AFHFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDN 1507
++ P ++ G GS+V +SS+A S Y +K AL LT+ LA E A N
Sbjct: 127 PALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRN 186
Query: 1506 IRTNCVAPWYIKTSLVKPLLEKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASYIT 1327
IR NC+AP IKTS + L K EE++ + R+GEPE+ + +V+FLC ASYIT
Sbjct: 187 IRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYIT 246
Query: 1326 GQVISVDGG 1300
G+ + V GG
Sbjct: 247 GETVVVGGG 255
>sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member 4 OS=Bos taurus
GN=DHRS4 PE=2 SV=1
Length = 260
Score = 150 bits (378), Expect = 4e-035
Identities = 91/249 (36%), Positives = 136/249 (54%), Gaps = 2/249 (0%)
Frame = -2
Query: 2043 KRWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVTG 1864
+R L K ALVT T GIG A+ LA+ GA V SR Q + + K GL VTG
Sbjct: 8 RRNPLDNKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKGEGLSVTG 67
Query: 1863 SVCDASDRDQREKLIEEVSSAFSGKLNILINNVGTN-IRKPTVEYTSEDYAKIMSINLES 1687
+VC + RE+L+ + G ++ILI+N + ++ E + KI+ +N+++
Sbjct: 68 TVCHVGKAEDRERLV-ATAVKLHGGVDILISNAAVSPFFGSLMDVPEEVWDKILDVNVKA 126
Query: 1686 AFHFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDN 1507
++ P + G GSIV +SS+A S Y +K AL LT+NLA E A N
Sbjct: 127 TALLTKAVVPEMAKRGGGSIVIVSSIAAYSPFPSLGPYNVSKTALLGLTKNLALELAESN 186
Query: 1506 IRTNCVAPWYIKTSLVKPLLEKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASYIT 1327
+R NC+AP I+TS + L E +E++ + + R+G+PEE + +V+FLC ASYIT
Sbjct: 187 VRVNCLAPGLIRTSFSRVLWEDPARQESIKATFQIKRIGKPEECAGIVSFLCSEDASYIT 246
Query: 1326 GQVISVDGG 1300
G+ + V GG
Sbjct: 247 GETVVVAGG 255
>sp|Q8WNV7|DHRS4_PIG Dehydrogenase/reductase SDR family member 4 OS=Sus scrofa
GN=DHRS4 PE=1 SV=1
Length = 260
Score = 145 bits (364), Expect = 2e-033
Identities = 88/249 (35%), Positives = 136/249 (54%), Gaps = 2/249 (0%)
Frame = -2
Query: 2043 KRWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVTG 1864
+R L K ALVT T GIG A+ LA+ GA V SR Q+ + + + GL VTG
Sbjct: 8 RRKPLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTG 67
Query: 1863 SVCDASDRDQREKLIEEVSSAFSGKLNILINNVGTN-IRKPTVEYTSEDYAKIMSINLES 1687
+VC + RE+L+ ++ G ++IL++N N ++ T E + KI+ +N+++
Sbjct: 68 TVCHVGKAEDRERLV-AMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKA 126
Query: 1686 AFHFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDN 1507
++ P ++ G GS++ +SSV + Y +K AL LT+NLA E A N
Sbjct: 127 TVLMTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRN 186
Query: 1506 IRTNCVAPWYIKTSLVKPLLEKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASYIT 1327
IR NC+AP IKT+ + L K +E + + R+G PE+ + +V+FLC ASYIT
Sbjct: 187 IRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYIT 246
Query: 1326 GQVISVDGG 1300
G+ + V GG
Sbjct: 247 GETVVVGGG 255
>sp|P0A9Q0|IDNO_ECOL6 Gluconate 5-dehydrogenase OS=Escherichia coli O6 GN=idnO
PE=3 SV=1
Length = 254
Score = 131 bits (327), Expect = 3e-029
Identities = 70/252 (27%), Positives = 127/252 (50%), Gaps = 1/252 (0%)
Frame = -2
Query: 2046 NKRWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVT 1867
N +SLAGK L+TG +GIG + L ++GA + + + ++ G+
Sbjct: 2 NDLFSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAV 61
Query: 1866 GSVCDASDRDQREKLIEEVSSAFSGKLNILINNVGTNIRKPTVEYTSEDYAKIMSINLES 1687
+ + + + + + +E + G +++L+NN G R P E+ +++ ++++N +
Sbjct: 62 AAPFNVTHKHEIDAAVEHIEKDI-GPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTA 120
Query: 1686 AFHFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDN 1507
F SQ + G ++ I S+ + + + Y A+KGA+ LTR + E A N
Sbjct: 121 VFLVSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHN 180
Query: 1506 IRTNCVAPWYIKTSLVKPLLEKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASYIT 1327
I+ N +AP Y KT + K L+E + F + RTP R G+P+E+ FL A+ ++
Sbjct: 181 IQVNGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDFVN 240
Query: 1326 GQVISVDGGFTV 1291
G ++ VDGG V
Sbjct: 241 GHLLFVDGGMLV 252
>sp|P0A9P9|IDNO_ECOLI Gluconate 5-dehydrogenase OS=Escherichia coli (strain K12)
GN=idnO PE=3 SV=1
Length = 254
Score = 131 bits (327), Expect = 3e-029
Identities = 70/252 (27%), Positives = 127/252 (50%), Gaps = 1/252 (0%)
Frame = -2
Query: 2046 NKRWSLAGKTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVT 1867
N +SLAGK L+TG +GIG + L ++GA + + + ++ G+
Sbjct: 2 NDLFSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAV 61
Query: 1866 GSVCDASDRDQREKLIEEVSSAFSGKLNILINNVGTNIRKPTVEYTSEDYAKIMSINLES 1687
+ + + + + + +E + G +++L+NN G R P E+ +++ ++++N +
Sbjct: 62 AAPFNVTHKHEIDAAVEHIEKDI-GPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTA 120
Query: 1686 AFHFSQIAHPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDN 1507
F SQ + G ++ I S+ + + + Y A+KGA+ LTR + E A N
Sbjct: 121 VFLVSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHN 180
Query: 1506 IRTNCVAPWYIKTSLVKPLLEKKGFEEAVVSRTPLGRVGEPEEVSSLVAFLCLPAASYIT 1327
I+ N +AP Y KT + K L+E + F + RTP R G+P+E+ FL A+ ++
Sbjct: 181 IQVNGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDFVN 240
Query: 1326 GQVISVDGGFTV 1291
G ++ VDGG V
Sbjct: 241 GHLLFVDGGMLV 252
>sp|P39640|BACC_BACSU Bacilysin biosynthesis oxidoreductase BacC OS=Bacillus
subtilis GN=bacC PE=3 SV=2
Length = 253
Score = 127 bits (317), Expect = 5e-028
Identities = 88/249 (35%), Positives = 128/249 (51%), Gaps = 9/249 (3%)
Frame = -2
Query: 2022 KTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVTGSVCDASD 1843
KT L+TGG GIG A V+ A G + + DE + K N + D +D
Sbjct: 6 KTVLITGGASGIGYAAVQ--AFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDITD 63
Query: 1842 RDQREKLIEEVSSAFSGKLNILINNVGTNIRKPTVEYTSEDYAKIMSINLESAFHFSQIA 1663
+ +E F G L++LINN G I P E D+ K++ +NL F S+ A
Sbjct: 64 EAACQHAVESAVHTFGG-LDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSKHA 122
Query: 1662 HPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDNIRTNCVAP 1483
+ A+G G+I+ SV GLV Y A+KG + QLT+++A ++A IR NCV P
Sbjct: 123 LKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCP 182
Query: 1482 WYIKTSL-VKPLLE-KKGFEEAVVSR----TPLGRVGEPEEVSSLVAFLCLPAASYITGQ 1321
I T L K LE +G E + PL R+G+PEE+++++ FL +SY+TG
Sbjct: 183 GIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYMTGS 242
Query: 1320 VISVDGGFT 1294
I+ DGG+T
Sbjct: 243 AITADGGYT 251
>sp|Q8KWT4|BACC2_BACSU Bacilysin biosynthesis oxidoreductase BacC OS=Bacillus
subtilis GN=bacC PE=3 SV=1
Length = 253
Score = 126 bits (315), Expect = 8e-028
Identities = 85/249 (34%), Positives = 130/249 (52%), Gaps = 9/249 (3%)
Frame = -2
Query: 2022 KTALVTGGTRGIGRAVVEELARFGATVHTCSRNQDELKSCLDDWKSNGLVVTGSVCDASD 1843
KT L+TGG GIG A V+ A V ++ + ++ + ++ L + D +D
Sbjct: 6 KTVLITGGASGIGYAAVQAFLNQQANVVVADIDEAQGEAMIRKENNDRLHFVHT--DITD 63
Query: 1842 RDQREKLIEEVSSAFSGKLNILINNVGTNIRKPTVEYTSEDYAKIMSINLESAFHFSQIA 1663
+ I F G L++LINN G I P E ++ K++++NL F S+ A
Sbjct: 64 EPACQNAIRSAVDKFGG-LDVLINNAGIEIVAPIHEMELSNWNKVLNVNLTGMFLMSKHA 122
Query: 1662 HPLLKASGVGSIVFISSVAGLVHLSSGSVYGATKGALNQLTRNLACEWAGDNIRTNCVAP 1483
+ SG G+I+ SV G+V Y A+KG + QLTR++A ++A NIR NCV P
Sbjct: 123 LKYMLKSGKGNIINTCSVGGVVAWPDIPAYNASKGGVLQLTRSMAVDYAKHNIRVNCVCP 182
Query: 1482 WYIKTSL-VKPLLE-KKGFEEAVVSR----TPLGRVGEPEEVSSLVAFLCLPAASYITGQ 1321
I T L K LE +G E + PL R+G+PEE+++++ FL +SY+TG
Sbjct: 183 GIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYMTGS 242
Query: 1320 VISVDGGFT 1294
I+ DGG+T
Sbjct: 243 AITADGGYT 251
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0
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