BLASTX 7.6.2
Query= UN17048 /QuerySize=1126
(1125 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 ... 414 5e-115
sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 ... 387 9e-107
sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 ... 368 4e-101
sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 ... 240 2e-062
sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 ... 240 2e-062
sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 ... 240 2e-062
sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 ... 238 7e-062
sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 ... 236 2e-061
sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 ... 234 1e-060
sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation ... 233 2e-060
sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2... 219 4e-056
sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 ... 215 6e-055
sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 ... 191 7e-048
sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 ... 178 8e-044
sp|C5A2A8|IF2B_THEGJ Translation initiation factor 2 subunit bet... 102 8e-021
sp|O58312|IF2B_PYRHO Translation initiation factor 2 subunit bet... 100 2e-020
sp|Q9UYR6|IF2B_PYRAB Translation initiation factor 2 subunit bet... 99 4e-020
sp|A2SSW2|IF2B_METLZ Translation initiation factor 2 subunit bet... 99 6e-020
sp|Q8U3I5|IF2B_PYRFU Translation initiation factor 2 subunit bet... 98 1e-019
sp|Q5V323|IF2B_HALMA Translation initiation factor 2 subunit bet... 92 8e-018
>sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 subunit beta
OS=Arabidopsis thaliana GN=EMB1401 PE=2 SV=3
Length = 268
Score = 414 bits (1064), Expect = 5e-115
Identities = 215/271 (79%), Positives = 235/271 (86%), Gaps = 10/271 (3%)
Frame = +1
Query: 115 LKEVKDEQE-LAPFDPTKKKKKKKVVLQDPIEEPTE-SPAEPSDSLPANDGGLDGPSFGT 288
+ E+++EQE LAPFDP+KKKKKKKVV+Q+P+E+ E S E SDSLP ND GL+ SF
Sbjct: 5 INEIREEQEQLAPFDPSKKKKKKKVVIQEPVEDLAESSQTEKSDSLPVND-GLES-SFTG 62
Query: 289 KKKKKKKPVESSSLDEETADAPEDLEEHPNEEEDA-EGIDLQQQQQQQRYPWEGSDRDYI 465
KKKKKKP ESS L+ E+ DA EDL+E N+E++ EGI L QQRYPWEGS+RDYI
Sbjct: 63 MKKKKKKPTESSLLNNESVDAGEDLDEIANDEQEGEEGIVL-----QQRYPWEGSERDYI 117
Query: 466 YDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHV 645
YDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHV
Sbjct: 118 YDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHV 177
Query: 646 MNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENR 825
M +LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRY+T+YVICLGCKSPDTILSKENR
Sbjct: 178 MQYLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYITDYVICLGCKSPDTILSKENR 237
Query: 826 LFFFRCEKCGSGRSVAQIKAGFVARVGRRKT 918
LFF RCEKCGS RSVA IK GFVARV RRKT
Sbjct: 238 LFFLRCEKCGSQRSVAPIKTGFVARVSRRKT 268
>sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 subunit beta
OS=Malus domestica PE=2 SV=2
Length = 271
Score = 387 bits (993), Expect = 9e-107
Identities = 197/266 (74%), Positives = 220/266 (82%), Gaps = 8/266 (3%)
Frame = +1
Query: 121 EVKDE--QELAPFDPTKKKKKKKVVLQDPIEEPTESPAEPSDSLPANDGGLDGPSFGTKK 294
EVKDE ++APFDPTKKKKKK+VV+QD ++ AE +++ A++G +F K
Sbjct: 8 EVKDEVVADIAPFDPTKKKKKKEVVIQDTTDDSVGKLAEKAEACTASEG--QESTFAGLK 65
Query: 295 KKKKKPVESSSLDEETADAPEDLEEHPNEEEDAEGIDLQQQQQQQRYPWEGSDRDYIYDE 474
KKKKKP+E+S L+EE+ DA EDL E E+E+ EGI L+ YPWEGSDRDY Y+E
Sbjct: 66 KKKKKPIETSILNEESGDAVEDLNERTGEDEEGEGIVLETPS----YPWEGSDRDYTYEE 121
Query: 475 LLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNF 654
LL RVF ILRENNP+LAGDRRRTVMRPPQVLREGTKK VFVNFMDLCKTMHRQPDHVM F
Sbjct: 122 LLDRVFTILRENNPDLAGDRRRTVMRPPQVLREGTKKAVFVNFMDLCKTMHRQPDHVMAF 181
Query: 655 LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFF 834
LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYV EYVICLGC+SPDTILSKENRLFF
Sbjct: 182 LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVNEYVICLGCQSPDTILSKENRLFF 241
Query: 835 FRCEKCGSGRSVAQIKAGFVARVGRR 912
RCEKCGSGRSVA KAGF+ARVGRR
Sbjct: 242 LRCEKCGSGRSVAPNKAGFMARVGRR 267
>sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 subunit beta
OS=Triticum aestivum PE=1 SV=1
Length = 270
Score = 368 bits (944), Expect = 4e-101
Identities = 189/267 (70%), Positives = 212/267 (79%), Gaps = 6/267 (2%)
Frame = +1
Query: 115 LKEVKDEQELAPFDPTKKKKKKKVVLQDPIEEPTESPAEPSDSLPANDGGLDGPSFGTKK 294
++ ++ E+APFDPTKKKKKKKVV+QDP +E + AE ++ L + G SF K
Sbjct: 7 MERKEEATEIAPFDPTKKKKKKKVVIQDPADE-VDKLAEKTEGLSVTESG--EASFVGLK 63
Query: 295 KKKKKPVESSSLDEETADAPEDLEEHPNEEEDAEGIDLQQQQQQQRYPWEGSDRDYIYDE 474
KKKKK VE E D + L++ E+E EGI L Q YPWEG+DRDY YDE
Sbjct: 64 KKKKKLVELDPSLVEAGDGEDTLDDQVGEDEQGEGIVLGGATQ---YPWEGTDRDYKYDE 120
Query: 475 LLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNF 654
LLGRVFNILRENNP+LAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQP+HVM F
Sbjct: 121 LLGRVFNILRENNPDLAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPEHVMMF 180
Query: 655 LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFF 834
LLAE+GTSGSLDGQQRLV+KGRFAPKNFE ILRRY+ EYVIC GCKSPDTILSKENRLFF
Sbjct: 181 LLAEMGTSGSLDGQQRLVIKGRFAPKNFEAILRRYINEYVICHGCKSPDTILSKENRLFF 240
Query: 835 FRCEKCGSGRSVAQIKAGFVARVGRRK 915
RCE+CGS RSVA IKAGFVA+VGRRK
Sbjct: 241 LRCEQCGSSRSVAPIKAGFVAQVGRRK 267
>sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 subunit 2
OS=Bos taurus GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 240 bits (610), Expect = 2e-062
Identities = 134/289 (46%), Positives = 178/289 (61%), Gaps = 8/289 (2%)
Frame = +1
Query: 52 KINPSPPKLISVAIMADENNELKEVKDEQELAPFDPTKKKKKKKVVLQ-DPIEEPTESPA 228
++ P P + V +++ + D +L F+ KKKKK K + D EE +
Sbjct: 43 EVEPEPTEDKDVEADEEDSRKKDASDDLDDLNFFNQKKKKKKSKKIFDIDEAEEGIKDLK 102
Query: 229 EPSDSLPANDGGLDGPSFGTKKKKKKKPVESSSLDEETADAPEDLEEHPNEEEDAEGIDL 408
SD + D KKKKKK V+ ++E + E LE+ ++++D GI
Sbjct: 103 IESDVQEPAEPEEDLDIMLGNKKKKKKVVKFPD-EDEVLEKDEALEDEDSKKDD--GISF 159
Query: 409 QQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKK 585
Q W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKK
Sbjct: 160 SNQTGP---AWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKK 216
Query: 586 TVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVT 765
T FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+
Sbjct: 217 TSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIK 276
Query: 766 EYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 912
EYV C C+SPDTIL K+ RL+F +CE C S SVA IK GF A GRR
Sbjct: 277 EYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGRR 325
>sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 subunit 2
OS=Homo sapiens GN=EIF2S2 PE=1 SV=2
Length = 333
Score = 240 bits (610), Expect = 2e-062
Identities = 134/274 (48%), Positives = 175/274 (63%), Gaps = 9/274 (3%)
Frame = +1
Query: 100 DENNELKEVKDE-QELAPFDPTKKKKK-KKVVLQDPIEEPTESPAEPSDSLPANDGGLDG 273
+E+ K+ D+ +L F+ KKKKK KK+ D EE + SD + D
Sbjct: 58 EEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIESDVQEPTEPEDDL 117
Query: 274 PSFGTKKKKKKKPVESSSLDEETADAPEDLEEHPNEEEDAEGIDLQQQQQQQRYPWEGSD 453
KKKKKK V+ ++E + E LE+ N+++D GI Q W GS+
Sbjct: 118 DIMLGNKKKKKKNVKFPD-EDEILEKDEALEDEDNKKDD--GISFSNQTGP---AWAGSE 171
Query: 454 RDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHR 630
RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +HR
Sbjct: 172 RDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHR 231
Query: 631 QPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTIL 810
QP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTIL
Sbjct: 232 QPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTIL 291
Query: 811 SKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 912
K+ RL+F +CE C S SVA IK GF A G+R
Sbjct: 292 QKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 325
>sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 subunit 2
OS=Mus musculus GN=Eif2s2 PE=1 SV=1
Length = 331
Score = 240 bits (610), Expect = 2e-062
Identities = 134/289 (46%), Positives = 180/289 (62%), Gaps = 10/289 (3%)
Frame = +1
Query: 52 KINPSPPKLISVAIMADENNELKEVKDEQELAPFDPTKKKKK-KKVVLQDPIEEPTESPA 228
++ P P + V +++ + D +L F+ KKKKK KK+ D EE +
Sbjct: 43 EVEPEPTEEKDVDADEEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEAIKDVK 102
Query: 229 EPSDSLPANDGGLDGPSFGTKKKKKKKPVESSSLDEETADAPEDLEEHPNEEEDAEGIDL 408
SD+ + D KKKKKK V+ ++E + E LE+ ++++D GI
Sbjct: 103 IESDAQEPAEPEDDLDIMLGNKKKKKKNVKFPE-EDEILEKDEALEDEDSKKDD--GISF 159
Query: 409 QQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKK 585
Q W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKK
Sbjct: 160 SSQT-----AWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKK 214
Query: 586 TVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVT 765
T FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+
Sbjct: 215 TSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIK 274
Query: 766 EYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 912
EYV C C+SPDTIL K+ RL+F +CE C S SVA IK GF A G+R
Sbjct: 275 EYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 323
>sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 subunit 2
OS=Pongo abelii GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 238 bits (606), Expect = 7e-062
Identities = 133/274 (48%), Positives = 174/274 (63%), Gaps = 9/274 (3%)
Frame = +1
Query: 100 DENNELKEVKDE-QELAPFDPTKKKKK-KKVVLQDPIEEPTESPAEPSDSLPANDGGLDG 273
+E+ K+ D+ +L F+ KKKKK KK+ D EE + SD + D
Sbjct: 58 EEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIESDVQEPTEPEDDL 117
Query: 274 PSFGTKKKKKKKPVESSSLDEETADAPEDLEEHPNEEEDAEGIDLQQQQQQQRYPWEGSD 453
KKKKKK V+ ++E + E LE+ N+++D GI Q W GS+
Sbjct: 118 DIMLGNKKKKKKNVKFPD-EDEILEKDEALEDEDNKKDD--GISFSNQTGP---AWAGSE 171
Query: 454 RDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHR 630
RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +HR
Sbjct: 172 RDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHR 231
Query: 631 QPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTIL 810
QP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTIL
Sbjct: 232 QPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTIL 291
Query: 811 SKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 912
K+ RL+F +CE C S S A IK GF A G+R
Sbjct: 292 QKDTRLYFLQCETCHSRCSAASIKTGFQAVTGKR 325
>sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 subunit 2
OS=Oryctolagus cuniculus GN=EIF2S2 PE=1 SV=1
Length = 333
Score = 236 bits (602), Expect = 2e-061
Identities = 133/289 (46%), Positives = 179/289 (61%), Gaps = 8/289 (2%)
Frame = +1
Query: 52 KINPSPPKLISVAIMADENNELKEVKDEQELAPFDPTKKKKK-KKVVLQDPIEEPTESPA 228
++ P P + V +++ + D +L F+ KKKKK KK+ D EE +
Sbjct: 43 EVEPEPTEDKDVEADEEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLK 102
Query: 229 EPSDSLPANDGGLDGPSFGTKKKKKKKPVESSSLDEETADAPEDLEEHPNEEEDAEGIDL 408
+D + D KKKKKK V+ ++E + E LE+ ++++D GI
Sbjct: 103 IENDVQEPAEPEDDLDIMLGNKKKKKKNVKFPD-EDEILEKDEALEDEDSKKDD--GISF 159
Query: 409 QQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKK 585
Q W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKK
Sbjct: 160 SNQTGP---AWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKK 216
Query: 586 TVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVT 765
T FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+
Sbjct: 217 TSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIK 276
Query: 766 EYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 912
EYV C C+SPDTIL K+ RL+F +CE C S SVA IK GF A G+R
Sbjct: 277 EYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 325
>sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 subunit 2
OS=Drosophila melanogaster GN=eIF-2beta PE=1 SV=1
Length = 312
Score = 234 bits (596), Expect = 1e-060
Identities = 134/267 (50%), Positives = 165/267 (61%), Gaps = 20/267 (7%)
Frame = +1
Query: 127 KDEQELAPFDPTKKKKKKKVVLQDPIEEPTES----PAEPSDSLPANDGGLDGPSFGTKK 294
+D +L F KKKKKKK D IE S S+ + LD KK
Sbjct: 53 EDNLDLESFG-KKKKKKKKPFNMDEIEAAIPSFGGDDVAASEEPEEEEINLDMDFSMAKK 111
Query: 295 KKKKKPVESSSLDEETADAPEDLEEHPNEEEDAEGIDLQQQQQQQRYPWEGSDRDYIYDE 474
KKK K E LDE AD +D ++ ED E + W GSDRDY YDE
Sbjct: 112 KKKSKKKE---LDELFADQADD-----DKSEDKE------NDEDNSSTWFGSDRDYTYDE 157
Query: 475 LLGRVFNILRENNPELAGDRR-RTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMN 651
LL RVF I+ + NP++A R+ + VMRPPQVLR GTKKT F NFMD+ KT+HR P H+++
Sbjct: 158 LLKRVFEIILDKNPDMAAGRKPKFVMRPPQVLRVGTKKTSFANFMDIAKTLHRLPKHLLD 217
Query: 652 FLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLF 831
FLLAELGTSGS+DG Q+L++KGRF PK E +LRRY+ EYV C C+SP+TIL K+ RLF
Sbjct: 218 FLLAELGTSGSMDGNQQLIIKGRFQPKQIENVLRRYIKEYVTCHTCRSPETILQKDTRLF 277
Query: 832 FFRCEKCGSGRSVAQIKAGFVARVGRR 912
F +CE CGS SVA IK+GF A G+R
Sbjct: 278 FLQCESCGSRCSVASIKSGFQAVTGKR 304
>sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation factor 2
subunit beta OS=Schizosaccharomyces pombe GN=tif212 PE=1 SV=2
Length = 321
Score = 233 bits (593), Expect = 2e-060
Identities = 132/289 (45%), Positives = 170/289 (58%), Gaps = 34/289 (11%)
Frame = +1
Query: 64 SPPKLISVAIMADENNELKEVKDEQELAPFDPTKKKKKKKVVLQDPIEEPTESPAEPSDS 243
S K ++ + E +ELK++ F KKKKK K + + S E ++
Sbjct: 59 SSAKDLTTPVTEGEVDELKDM--------FSSMKKKKKSK--------KSSASAEEQTED 102
Query: 244 LPANDGGLDGPSFGTKKKKKKKPVESSSLDEE-----TADAPEDLEEHPNEEEDAEGIDL 408
+ G LD S KKKKKKK + S+ ++E T DA DL + + E+
Sbjct: 103 ITTESGELDFSSM-KKKKKKKKSADLSAFEKELEASSTGDATSDLSKQTFDSEN------ 155
Query: 409 QQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKT 588
+ W SDRDY Y ELL R F +LR NNPELAG++R+ + PP V REG KKT
Sbjct: 156 -----MGEHAWLKSDRDYYYPELLNRFFTLLRTNNPELAGEKRKYTIVPPSVHREG-KKT 209
Query: 589 VFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTE 768
+F N D+ K MHR DHV+ FL AELGTSGS+DG RL++KGRF K E +LRRY+ E
Sbjct: 210 IFANISDISKRMHRSLDHVIQFLFAELGTSGSVDGSSRLIIKGRFQQKQIENVLRRYIVE 269
Query: 769 YVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRRK 915
YV C CKSPDTIL+KENR+FF CE CGS RSV IK G+ A++G+RK
Sbjct: 270 YVTCKTCKSPDTILTKENRIFFMTCEACGSVRSVQAIKTGYQAQIGKRK 318
>sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2 subunit 2-like
protein OS=Homo sapiens PE=1 SV=1
Length = 327
Score = 219 bits (556), Expect = 4e-056
Identities = 109/190 (57%), Positives = 138/190 (72%), Gaps = 6/190 (3%)
Frame = +1
Query: 346 DAPEDLEEHPNEEEDAEGIDLQQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL- 522
D E LE+ N+++D GI Q W GS+RDY Y+ELL RVFNI+RE NP++
Sbjct: 135 DEDEALEDEDNKKDD--GISFSNQTGP---AWAGSERDYTYEELLNRVFNIMREKNPDMV 189
Query: 523 AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQR 702
AG++R+ VM+PPQV+R GTKKT FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +
Sbjct: 190 AGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQ 249
Query: 703 LVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIK 882
LV+KGRF K E +LRRY+ EYV C C+SPDTIL K+ RL+F +CE C S SVA IK
Sbjct: 250 LVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDMRLYFLQCETCHSRCSVAIIK 309
Query: 883 AGFVARVGRR 912
GF A +G+R
Sbjct: 310 IGFQAVMGKR 319
>sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 subunit 2
OS=Dictyostelium discoideum GN=eif2s2 PE=3 SV=1
Length = 317
Score = 215 bits (546), Expect = 6e-055
Identities = 112/274 (40%), Positives = 169/274 (61%), Gaps = 14/274 (5%)
Frame = +1
Query: 82 SVAIMADENNELKEVKDEQELAPFDPTKKKKKKKVVLQDPIEEPTESPAEPSDSLPANDG 261
++A+M+ + +E +E +DE++ +K+KKKK L E E ++ A+D
Sbjct: 40 TLAMMSQQEDE-QEQEDEKK-------EKRKKKKAALLASTEGENSEAIEKLENEGAHDE 91
Query: 262 GLDGPSFGTKKKKKKKPVES-SSLDEETADAPEDLEEHPNEEEDAEGIDLQQQQ----QQ 426
++ G KKKKKK S ++ T E E P E+ +++ + Q
Sbjct: 92 DIEAEFMGEKKKKKKSSKSSTTTTTSTTTTTTEPTETEPTEDGESKEKTITTSDGDTFVQ 151
Query: 427 QRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFM 606
PW G+DRDY Y EL R++++L+ NNP+L D++RT M+PPQV+REGTKKT++ NF
Sbjct: 152 GTIPWAGTDRDYKYSELTYRIYHLLQANNPDLISDQKRT-MKPPQVMREGTKKTIWANFA 210
Query: 607 DLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLG 786
++C T++R+ +HV N++ AELGT+GS+DG QRLV++GRF E ++R Y++EYV C
Sbjct: 211 EICGTLNRKVEHVYNYVFAELGTNGSIDGNQRLVIRGRFKTSQIEIVIRHYISEYVACRN 270
Query: 787 CKSPDTILSKENRLFFFRCEKCGSGRSVAQIKAG 888
CKSP+T+L + NRL+F C C S RSVA IK G
Sbjct: 271 CKSPNTVLERNNRLYFLCCNACNSKRSVAVIKKG 304
>sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 subunit beta
OS=Saccharomyces cerevisiae GN=SUI3 PE=1 SV=2
Length = 285
Score = 191 bits (485), Expect = 7e-048
Identities = 118/255 (46%), Positives = 148/255 (58%), Gaps = 25/255 (9%)
Frame = +1
Query: 163 KKKKKKKVVLQDPIEEPTESPAEPSDSLPANDGGLDGPSFGTKKKKKKKPVESSSLDEET 342
KKKKK K V D E+ EP+D + G L + KKKKKK +SS E
Sbjct: 50 KKKKKSKSVSAD-----AEAEKEPTDDIAEALGEL------SLKKKKKKTKDSSVDAFEK 98
Query: 343 ADAPEDLEEHPNEEEDAEGIDLQQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL 522
A L+ E ++ QQ+ P Y ELL R FNILR NNPEL
Sbjct: 99 ELAKAGLDNVDAESKEGTPSANSSIQQEVGLP---------YSELLSRFFNILRTNNPEL 149
Query: 523 AGDRRRTVMR--PPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQ 696
AGDR R PP LR+G KKT+F N D+ + +HR P+H++ +L AELGTSGS+DGQ
Sbjct: 150 AGDRSGPKFRIPPPVCLRDG-KKTIFSNIQDIAEKLHRSPEHLIQYLFAELGTSGSVDGQ 208
Query: 697 QRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE--NRLFFFRCEKCGSGRSV 870
+RLV+KG+F K E +LRRY+ EYV C CKS +T L +E NRLFF C+ CGS RSV
Sbjct: 209 KRLVIKGKFQSKQMENVLRRYILEYVTCKTCKSINTELKREQSNRLFFMVCKSCGSTRSV 268
Query: 871 AQIKAGFVARVGRRK 915
+ IK GF A VG+R+
Sbjct: 269 SSIKTGFQATVGKRR 283
>sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 subunit 2
OS=Caenorhabditis elegans GN=K04G2.1 PE=3 SV=4
Length = 250
Score = 178 bits (450), Expect = 8e-044
Identities = 80/157 (50%), Positives = 115/157 (73%)
Frame = +1
Query: 442 EGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKT 621
+G+ DY Y+E L V+ ++++ NP+ AGD+++ ++ P+V R G+KKT F NF+++C+
Sbjct: 81 KGAWPDYTYEEALTLVYQVMKDKNPDFAGDKKKFAIKLPEVARAGSKKTAFSNFLEICRL 140
Query: 622 MHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPD 801
M RQ HV+ FLLAELGT+GS+DG L+VKGR+ K FE +LR+Y+ EYV+C CKSP+
Sbjct: 141 MKRQDKHVLQFLLAELGTTGSIDGSNCLIVKGRWQQKQFESVLRKYIKEYVMCHTCKSPE 200
Query: 802 TILSKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 912
T L+K+ RLFF +C CGS SV IK+GF A VG+R
Sbjct: 201 TQLTKDTRLFFLQCTNCGSRCSVTAIKSGFKAVVGKR 237
>sp|C5A2A8|IF2B_THEGJ Translation initiation factor 2 subunit beta
OS=Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
GN=eIF2B PE=3 SV=1
Length = 142
Score = 102 bits (252), Expect = 8e-021
Identities = 48/133 (36%), Positives = 80/133 (60%), Gaps = 5/133 (3%)
Frame = +1
Query: 460 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 639
Y ++ LL + + E PE + PP V+ +T+ NF+D+ + M+R P
Sbjct: 8 YDFERLLDKAY----EELPENVKSHKSRFEVPPAVVTIAGNRTIIENFVDIAEAMNRDPS 63
Query: 640 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 819
H++ F+L E+ T+G+L+G +R++++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 64 HLLKFILREVATAGTLEG-RRVILQGRFTPYLIANKLKKYLKEYVICPVCGSPDTKIIKR 122
Query: 820 NRLFFFRCEKCGS 858
+R +F +CE CG+
Sbjct: 123 DRFYFLKCEACGA 135
>sp|O58312|IF2B_PYRHO Translation initiation factor 2 subunit beta OS=Pyrococcus
horikoshii GN=eif2b PE=3 SV=1
Length = 140
Score = 100 bits (248), Expect = 2e-020
Identities = 52/133 (39%), Positives = 82/133 (61%), Gaps = 5/133 (3%)
Frame = +1
Query: 460 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 639
Y Y++LL + + L EN + + R + V EG KT+ NF D+ + ++R P
Sbjct: 6 YDYEKLLEKAYEELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIAEALNRDPQ 61
Query: 640 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 819
H++ FLL E+ T+G+L+G +R+V++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-KRVVLQGRFTPYLIANKLKKYIKEYVICPVCGSPDTKIIKR 120
Query: 820 NRLFFFRCEKCGS 858
+R +F +CE CG+
Sbjct: 121 DRFYFLKCEACGA 133
>sp|Q9UYR6|IF2B_PYRAB Translation initiation factor 2 subunit beta OS=Pyrococcus
abyssi GN=eif2b PE=3 SV=1
Length = 140
Score = 99 bits (246), Expect = 4e-020
Identities = 51/133 (38%), Positives = 82/133 (61%), Gaps = 5/133 (3%)
Frame = +1
Query: 460 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 639
Y Y++LL + + L EN + + R + V EG KT+ NF D+ + ++R P
Sbjct: 6 YDYEKLLEKAYEELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIAEALNRDPQ 61
Query: 640 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 819
H++ FLL E+ T+G+L+G +R+V++GRF P +++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-KRVVLQGRFTPYLIANKIKKYIKEYVICPVCGSPDTKIIKR 120
Query: 820 NRLFFFRCEKCGS 858
+R +F +CE CG+
Sbjct: 121 DRFYFLKCEACGA 133
>sp|A2SSW2|IF2B_METLZ Translation initiation factor 2 subunit beta
OS=Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)
GN=eIF2B PE=3 SV=1
Length = 204
Score = 99 bits (244), Expect = 6e-020
Identities = 52/116 (44%), Positives = 69/116 (59%), Gaps = 2/116 (1%)
Frame = +1
Query: 538 RTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKG 717
R VM ++ EG K TV NF D+ +++R DH M F+L ELGT+G +DG R V G
Sbjct: 25 RFVMPKAKIYIEG-KTTVLENFSDIVDSLNRDKDHFMKFILGELGTAGKIDG-NRAVFNG 82
Query: 718 RFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKA 885
+F F+ IL YV +YVIC C PDT L K++R+ CE CGS R + + KA
Sbjct: 83 KFEQAQFDAILETYVGDYVICSECGRPDTKLVKDDRVLMLLCEACGSKRPIRKRKA 138
>sp|Q8U3I5|IF2B_PYRFU Translation initiation factor 2 subunit beta OS=Pyrococcus
furiosus GN=eif2b PE=1 SV=1
Length = 140
Score = 98 bits (242), Expect = 1e-019
Identities = 52/133 (39%), Positives = 80/133 (60%), Gaps = 5/133 (3%)
Frame = +1
Query: 460 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 639
Y Y++LL + + L EN + + R + V EG KT+ NF D+ ++R P
Sbjct: 6 YDYEKLLEKAYQELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIADALNRDPQ 61
Query: 640 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 819
H++ FLL E+ T+G+L+G +R+V++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-RRVVLQGRFTPYLIANKLKKYIKEYVICPVCGSPDTKIIKR 120
Query: 820 NRLFFFRCEKCGS 858
+R F +CE CG+
Sbjct: 121 DRFHFLKCEACGA 133
>sp|Q5V323|IF2B_HALMA Translation initiation factor 2 subunit beta OS=Haloarcula
marismortui GN=eif2B PE=3 SV=1
Length = 134
Score = 92 bits (226), Expect = 8e-018
Identities = 46/124 (37%), Positives = 65/124 (52%), Gaps = 1/124 (0%)
Frame = +1
Query: 505 ENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGS 684
E PE+ G R + P + +EG TV+ NF C + R+ DHVM FL +LGTSG
Sbjct: 12 EETPEIDGTSERFEVPDPDIRQEG-NVTVYENFQSTCSRLGREDDHVMKFLQNDLGTSGH 70
Query: 685 LDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFFRCEKCGSGR 864
+D R+ + G F E + YV E+V+C C PDT L +E RCE CG+
Sbjct: 71 IDESGRVRLTGEFDATRIEASIDEYVDEFVLCSECGLPDTQLEREQGALLLRCEACGARS 130
Query: 865 SVAQ 876
+ ++
Sbjct: 131 ATSE 134
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0
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