BLASTX 7.6.2
Query= UN17052 /QuerySize=992
(991 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9LD45|BI1_ARATH Bax inhibitor 1 OS=Arabidopsis thaliana GN=B... 469 2e-131
sp|Q9MBD8|BI1_ORYSJ Bax inhibitor 1 OS=Oryza sativa subsp. japon... 344 6e-094
sp|Q9IA79|BI1_PAROL Probable Bax inhibitor 1 OS=Paralichthys oli... 191 1e-047
sp|Q0V882|BI1_BOVIN Bax inhibitor 1 OS=Bos taurus GN=TMBIM6 PE=2... 189 3e-047
sp|P55061|BI1_HUMAN Bax inhibitor 1 OS=Homo sapiens GN=TMBIM6 PE... 189 3e-047
sp|Q9D2C7|BI1_MOUSE Bax inhibitor 1 OS=Mus musculus GN=Tmbim6 PE... 189 3e-047
sp|Q66RM2|BI1_PIG Bax inhibitor 1 OS=Sus scrofa GN=TMBIM6 PE=2 SV=1 189 4e-047
sp|Q5R7R1|BI1_PONAB Bax inhibitor 1 OS=Pongo abelii GN=TMBIM6 PE... 187 2e-046
sp|P55062|BI1_RAT Bax inhibitor 1 OS=Rattus norvegicus GN=Tmbim6... 185 6e-046
sp|Q9VSH3|BI1_DROME Probable Bax inhibitor 1 OS=Drosophila melan... 120 2e-026
>sp|Q9LD45|BI1_ARATH Bax inhibitor 1 OS=Arabidopsis thaliana GN=BI-1 PE=1 SV=1
Length = 247
Score = 469 bits (1205), Expect = 2e-131
Identities = 233/247 (94%), Positives = 241/247 (97%)
Frame = +3
Query: 54 MESFSSFFDSQPGSRSWSYDSLKNLRQISPAVQNHLKRVYLTLCCALVASAFGAYLHMLW 233
M++FSSFFDSQPGSRSWSYDSLKN RQISPAVQNHLKRVYLTLCCALVASAFGAYLH+LW
Sbjct: 1 MDAFSSFFDSQPGSRSWSYDSLKNFRQISPAVQNHLKRVYLTLCCALVASAFGAYLHVLW 60
Query: 234 NIGGILTTIGCFGSMIWLLSCPPYEQQKRLLLLFLSAVLEGASVGPLIKVAVDFDPSILI 413
NIGGILTTIGC G+MIWLLSCPPYE QKRL LLF+SAVLEGASVGPLIKVA+D DPSILI
Sbjct: 61 NIGGILTTIGCIGTMIWLLSCPPYEHQKRLSLLFVSAVLEGASVGPLIKVAIDVDPSILI 120
Query: 414 TAFVGTAIAFICFSGAAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFEL 593
TAFVGTAIAF+CFS AAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFEL
Sbjct: 121 TAFVGTAIAFVCFSAAAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFEL 180
Query: 594 YFGLLIFVGYMVVDTQDIIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEE 773
YFGLLIFVGYMVVDTQ+IIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEE
Sbjct: 181 YFGLLIFVGYMVVDTQEIIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEE 240
Query: 774 KKKKRRN 794
KKKKRRN
Sbjct: 241 KKKKRRN 247
>sp|Q9MBD8|BI1_ORYSJ Bax inhibitor 1 OS=Oryza sativa subsp. japonica GN=BI1 PE=2
SV=1
Length = 249
Score = 344 bits (882), Expect = 6e-094
Identities = 174/249 (69%), Positives = 210/249 (84%), Gaps = 2/249 (0%)
Frame = +3
Query: 54 MESFSSFFDSQPGSRS-WSYDSLKNLRQISPAVQNHLKRVYLTLCCALVASAFGAYLHML 230
M++F S + + S W YDSLKN RQISPAVQ+HLK VYLTLC AL ASA GAYLH+
Sbjct: 1 MDAFYSTSSAYGAAASGWGYDSLKNFRQISPAVQSHLKLVYLTLCVALAASAVGAYLHVA 60
Query: 231 WNIGGILTTIGCFGSMIWLLSCPPYEQQKRLLLLFLSAVLEGASVGPLIKVAVDFDPSIL 410
NIGG+LT +GC GS+ WL S P +E++KR +L +A+LEGASVGPLIK+AVDFD SIL
Sbjct: 61 LNIGGMLTMLGCVGSIAWLFSVPVFEERKRFGILLAAALLEGASVGPLIKLAVDFDSSIL 120
Query: 411 ITAFVGTAIAFICFSGAAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFE 590
+TAFVGTAIAF CF+ AA++A+RREYLYLGGLLSSGLS+L+WLQFA+SIFG S F FE
Sbjct: 121 VTAFVGTAIAFGCFTCAAIVAKRREYLYLGGLLSSGLSILLWLQFAASIFGHSTGSFMFE 180
Query: 591 LYFGLLIFVGYMVVDTQDIIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADK- 767
+YFGLLIF+GYMV DTQ+IIE+AH GDMDY+KH+LTLFTDFVAV VRIL+IMLKN++DK
Sbjct: 181 VYFGLLIFLGYMVYDTQEIIERAHHGDMDYIKHALTLFTDFVAVLVRILVIMLKNASDKS 240
Query: 768 EEKKKKRRN 794
EEKK+K+R+
Sbjct: 241 EEKKRKKRS 249
>sp|Q9IA79|BI1_PAROL Probable Bax inhibitor 1 OS=Paralichthys olivaceus
GN=tmbim6 PE=2 SV=1
Length = 237
Score = 191 bits (483), Expect = 1e-047
Identities = 99/233 (42%), Positives = 152/233 (65%), Gaps = 5/233 (2%)
Frame = +3
Query: 96 RSWSYDSLKNLRQISPAVQNHLKRVYLTLCCALVASAFGAYLHMLWNI--GGILTTIGCF 269
R+ ++DSL QIS + Q HLK VY +L + +A G+Y+H++ + GG+L+ +G
Sbjct: 6 RNINFDSLFKFSQISHSTQVHLKNVYSSLAVCMFVAAAGSYVHVVTRLFQGGMLSVLGSL 65
Query: 270 GSMIWLLSCP--PYEQQKRLLLLFLSAVLEGASVGPLIKVAVDFDPSILITAFVGTAIAF 443
G M WL P ++KRL +L A L G + P + + +PSI++TAF+GT++ F
Sbjct: 66 GMMFWLAMTPHNSETEKKRLAILAGFAFLTGVGLCPTLDFVIAINPSIIVTAFLGTSVIF 125
Query: 444 ICFSGAAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFELYFGLLIFVGY 623
+CF+ +A+ A+RR YL+LGG L SGLS+L +L ++F GS +FK +Y GLLI G+
Sbjct: 126 VCFTLSALYAKRRSYLFLGGTLMSGLSIL-FLMSMMNMFFGSVMLFKAHMYLGLLIMCGF 184
Query: 624 MVVDTQDIIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEEKKK 782
++ DTQ IIEKA GD DYV HS+ LF DF+ +F ++++I+ N DK+++KK
Sbjct: 185 VLXDTQLIIEKAENGDKDYVWHSVDLFLDFITIFRKLMVILALNDKDKKKEKK 237
>sp|Q0V882|BI1_BOVIN Bax inhibitor 1 OS=Bos taurus GN=TMBIM6 PE=2 SV=1
Length = 236
Score = 189 bits (479), Expect = 3e-047
Identities = 99/232 (42%), Positives = 150/232 (64%), Gaps = 5/232 (2%)
Frame = +3
Query: 96 RSWSYDSLKNLRQISPAVQNHLKRVYLTLCCALVASAFGAYLHMLWNI--GGILTTIGCF 269
R ++D+L I+P+ Q HLK+VY + + +A GAY+H++ + G+L+ +G
Sbjct: 6 RKINFDALFKFSHITPSTQQHLKKVYASFALCMFVAAAGAYIHVVTHFIQAGLLSALGSL 65
Query: 270 GSMIWLLSCPPYE--QQKRLLLLFLSAVLEGASVGPLIKVAVDFDPSILITAFVGTAIAF 443
G MIWL++ P +QKRL LL A L G +GP + + + +PSIL TAF+GTA+ F
Sbjct: 66 GLMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALDLCIAINPSILPTAFMGTAMIF 125
Query: 444 ICFSGAAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFELYFGLLIFVGY 623
CF+ +A+ ARRR YL+LGG+L S +S LM L ++F GS +F+ LY GL++ G+
Sbjct: 126 TCFTLSALYARRRSYLFLGGILMSAMS-LMLLSSLGNLFFGSVWLFQANLYMGLVVMCGF 184
Query: 624 MVVDTQDIIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEEKK 779
++ DTQ IIEKA GD DY+ H + LF DFV +F ++++I+ N DK++KK
Sbjct: 185 VLFDTQLIIEKAENGDKDYIWHCVDLFLDFVTLFRKLMMILAMNEKDKKKKK 236
>sp|P55061|BI1_HUMAN Bax inhibitor 1 OS=Homo sapiens GN=TMBIM6 PE=1 SV=2
Length = 237
Score = 189 bits (479), Expect = 3e-047
Identities = 99/233 (42%), Positives = 151/233 (64%), Gaps = 5/233 (2%)
Frame = +3
Query: 96 RSWSYDSLKNLRQISPAVQNHLKRVYLTLCCALVASAFGAYLHMLWNI--GGILTTIGCF 269
R ++D+L I+P+ Q HLK+VY + + +A GAY+HM+ + G+L+ +G
Sbjct: 6 RKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHMVTHFIQAGLLSALGSL 65
Query: 270 GSMIWLLSCPPYE--QQKRLLLLFLSAVLEGASVGPLIKVAVDFDPSILITAFVGTAIAF 443
MIWL++ P +QKRL LL A L G +GP ++ + +PSIL TAF+GTA+ F
Sbjct: 66 ILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIAVNPSILPTAFMGTAMIF 125
Query: 444 ICFSGAAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFELYFGLLIFVGY 623
CF+ +A+ ARRR YL+LGG+L S LS+L+ L ++F GS +F+ LY GL++ G+
Sbjct: 126 TCFTLSALYARRRSYLFLGGILMSALSLLL-LSSLGNVFFGSIWLFQANLYVGLVVMCGF 184
Query: 624 MVVDTQDIIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEEKKK 782
++ DTQ IIEKA GD DY+ H + LF DF+ VF ++++I+ N DK+++KK
Sbjct: 185 VLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMILAMNEKDKKKEKK 237
>sp|Q9D2C7|BI1_MOUSE Bax inhibitor 1 OS=Mus musculus GN=Tmbim6 PE=2 SV=1
Length = 237
Score = 189 bits (479), Expect = 3e-047
Identities = 100/233 (42%), Positives = 151/233 (64%), Gaps = 5/233 (2%)
Frame = +3
Query: 96 RSWSYDSLKNLRQISPAVQNHLKRVYLTLCCALVASAFGAYLHMLWNI--GGILTTIGCF 269
R ++D+L I+P+ Q HLK+VY + + +A GAY+H++ + G+L+ +G
Sbjct: 6 RKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHVVTHFIQAGLLSALGSL 65
Query: 270 GSMIWLLSCPPYE--QQKRLLLLFLSAVLEGASVGPLIKVAVDFDPSILITAFVGTAIAF 443
MIWL++ P +QKRL LL A L G +GP +++ + +PSIL TAF+GTA+ F
Sbjct: 66 ALMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALELCIAVNPSILPTAFMGTAMIF 125
Query: 444 ICFSGAAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFELYFGLLIFVGY 623
CFS +A+ ARRR YL+LGG+L S +S LM L ++F GS +F+ LY GLL+ G+
Sbjct: 126 TCFSLSALYARRRSYLFLGGILMSAMS-LMLLSSLGNLFFGSIWLFQANLYLGLLVMCGF 184
Query: 624 MVVDTQDIIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEEKKK 782
++ DTQ IIEKA GD DY+ H + LF DFV +F ++++I+ N DK+++KK
Sbjct: 185 VLFDTQLIIEKAEHGDKDYIWHCVDLFLDFVTLFRKLMLILAFNEKDKKKEKK 237
>sp|Q66RM2|BI1_PIG Bax inhibitor 1 OS=Sus scrofa GN=TMBIM6 PE=2 SV=1
Length = 237
Score = 189 bits (478), Expect = 4e-047
Identities = 99/233 (42%), Positives = 151/233 (64%), Gaps = 5/233 (2%)
Frame = +3
Query: 96 RSWSYDSLKNLRQISPAVQNHLKRVYLTLCCALVASAFGAYLHMLWNI--GGILTTIGCF 269
R ++D+L I+P+ Q HLK+VY + + +A GAY+H++ G+L+ +G
Sbjct: 6 RKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHVVTRFIQAGLLSALGSL 65
Query: 270 GSMIWLLSCPPYE--QQKRLLLLFLSAVLEGASVGPLIKVAVDFDPSILITAFVGTAIAF 443
G MIWL++ P +QKRL LL A L G +GP + + + +PSIL TAF+GTA+ F
Sbjct: 66 GLMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALDLCIAINPSILPTAFMGTAMIF 125
Query: 444 ICFSGAAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFELYFGLLIFVGY 623
CF+ +A+ ARRR YL+LGG+L S +S LM L ++F GS +F+ LY GL++ G+
Sbjct: 126 TCFTLSALYARRRSYLFLGGILMSAMS-LMVLSSLGNLFFGSIWLFQANLYVGLVVMCGF 184
Query: 624 MVVDTQDIIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEEKKK 782
++ DTQ IIEKA GD DY+ H + LF+DFV +F ++++I+ N DK+++KK
Sbjct: 185 VLFDTQLIIEKAENGDKDYIWHCVDLFSDFVTLFRKLMMILAMNEKDKKKEKK 237
>sp|Q5R7R1|BI1_PONAB Bax inhibitor 1 OS=Pongo abelii GN=TMBIM6 PE=2 SV=2
Length = 237
Score = 187 bits (473), Expect = 2e-046
Identities = 97/233 (41%), Positives = 151/233 (64%), Gaps = 5/233 (2%)
Frame = +3
Query: 96 RSWSYDSLKNLRQISPAVQNHLKRVYLTLCCALVASAFGAYLHMLWNI--GGILTTIGCF 269
R ++D+L I+P+ Q HLK+VY + + +A GAY+H++ + G+L+ +G
Sbjct: 6 RKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHVVTHFIQAGLLSALGSL 65
Query: 270 GSMIWLLSCPPYE--QQKRLLLLFLSAVLEGASVGPLIKVAVDFDPSILITAFVGTAIAF 443
MIWL++ P +QKRL LL A L G +GP ++ + +PSIL TAF+GTA+ F
Sbjct: 66 ILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCITVNPSILPTAFMGTAMIF 125
Query: 444 ICFSGAAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFELYFGLLIFVGY 623
CF+ +A+ ARRR YL+LGG+L S LS+L+ L ++F GS +F+ LY GL++ G+
Sbjct: 126 TCFTLSALYARRRSYLFLGGILMSALSLLL-LSSLGNVFFGSIWLFQANLYVGLVVMCGF 184
Query: 624 MVVDTQDIIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEEKKK 782
++ DTQ IIEKA GD DY+ H + LF DF+ +F ++++I+ N DK+++KK
Sbjct: 185 VLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITLFRKLMMILAMNEKDKKKEKK 237
>sp|P55062|BI1_RAT Bax inhibitor 1 OS=Rattus norvegicus GN=Tmbim6 PE=2 SV=2
Length = 237
Score = 185 bits (468), Expect = 6e-046
Identities = 98/233 (42%), Positives = 150/233 (64%), Gaps = 5/233 (2%)
Frame = +3
Query: 96 RSWSYDSLKNLRQISPAVQNHLKRVYLTLCCALVASAFGAYLHMLWNI--GGILTTIGCF 269
R ++D+L I+P+ Q HLK+VY + + +A GAY+H++ G+L+ +G
Sbjct: 6 RKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHVVTRFIQAGLLSALGAL 65
Query: 270 GSMIWLLSCPPYE--QQKRLLLLFLSAVLEGASVGPLIKVAVDFDPSILITAFVGTAIAF 443
MI L++ P +QKRL LL A L G +GP +++ + +PSIL TAF+GTA+ F
Sbjct: 66 ALMICLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALELCIAINPSILPTAFMGTAMIF 125
Query: 444 ICFSGAAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFELYFGLLIFVGY 623
CFS +A+ ARRR YL+LGG+L S +S LM++ ++F GS +F+ LY GLL+ G+
Sbjct: 126 TCFSLSALYARRRSYLFLGGILMSAMS-LMFVSSLGNLFFGSIWLFQANLYMGLLVMCGF 184
Query: 624 MVVDTQDIIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEEKKK 782
++ DTQ IIEKA GD DY+ H + LF DFV +F ++++I+ N DK+++KK
Sbjct: 185 VLFDTQLIIEKAEHGDKDYIWHCIDLFLDFVTLFRKLMLILAFNEKDKKKEKK 237
>sp|Q9VSH3|BI1_DROME Probable Bax inhibitor 1 OS=Drosophila melanogaster
GN=CG7188 PE=1 SV=1
Length = 245
Score = 120 bits (300), Expect = 2e-026
Identities = 73/222 (32%), Positives = 123/222 (55%), Gaps = 12/222 (5%)
Frame = +3
Query: 141 PAVQNHLKRVYLTLCCALVASAFGAYLHMLWNIGGILTTIGCFGSMIWLLSCPPYEQQ-- 314
P V+ HL +VY+ L A+A GA L M + L + +++ +L Y+
Sbjct: 25 PYVREHLSKVYMVLGSTAAATAMGAMLQMRDFLD--LGVLAAVATLVLVLGLHFYKDDGK 82
Query: 315 ---KRLLLLFLSAVLEGASVGPLIKVAVDFDPSILITAFVGTAIAFICFSGAAMLARRRE 485
RL +L+ G ++GPL+ +P+I+++A GT + FI S +A+LA + +
Sbjct: 83 NYYTRLGMLYAFGFCSGQTLGPLLGYICSINPAIILSALTGTFVTFISLSLSALLAEQGK 142
Query: 486 YLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFELYFGLLIFVGYMVVDTQDIIEKAHL 665
YLYLGG+L S ++ + L + +F S + +LY G+ + ++V DTQ+I+EK
Sbjct: 143 YLYLGGMLVSVINTMALLSLFNMVF-KSYFVQVTQLYVGVFVMAAFIVYDTQNIVEKCRN 201
Query: 666 GDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEEKKKKRR 791
G+ D V+H+L LF D +++F R+LII+ KEE+K+ R
Sbjct: 202 GNRDVVQHALDLFFDVLSMFRRLLIIL----TQKEERKQNER 239
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0
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