BLASTX 7.6.2
Query= UN17055 /QuerySize=872
(871 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain-containing prot... 105 5e-022
sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain-containing prot... 102 3e-021
sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain-containing prot... 101 1e-020
sp|Q63584|TMEDA_RAT Transmembrane emp24 domain-containing protei... 100 2e-020
sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain-containing prot... 99 3e-020
sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 OS=Mesocricetu... 99 3e-020
sp|Q5RE32|TMEDA_PONAB Transmembrane emp24 domain-containing prot... 99 4e-020
sp|Q90515|TMEDA_TAKRU Transmembrane emp24 domain-containing prot... 99 4e-020
sp|B4NIY1|TMEDA_DROWI Transmembrane emp24 domain-containing prot... 94 8e-019
sp|B3LVB0|TMEDA_DROAN Transmembrane emp24 domain-containing prot... 94 1e-018
sp|B4JYU5|TMEDA_DROGR Transmembrane emp24 domain-containing prot... 91 9e-018
sp|A0AQ71|TMEDA_DROSI Transmembrane emp24 domain-containing prot... 91 1e-017
sp|B3P6T8|TMEDA_DROER Transmembrane emp24 domain-containing prot... 90 2e-017
sp|B4PUZ3|TMEDA_DROYA Transmembrane emp24 domain-containing prot... 90 2e-017
sp|Q8SXY6|TMEDA_DROME Transmembrane emp24 domain-containing prot... 89 4e-017
sp|B4K4G5|TMEDA_DROMO Transmembrane emp24 domain-containing prot... 89 4e-017
sp|B4GE47|TMEDA_DROPE Transmembrane emp24 domain-containing prot... 89 4e-017
sp|B4MGF8|TMEDA_DROVI Transmembrane emp24 domain-containing prot... 89 4e-017
sp|Q9D2R4|TMD11_MOUSE Transmembrane emp24 domain-containing prot... 67 2e-010
sp|Q4WQL0|TMEDA_ASPFU Endoplasmic reticulum vesicle protein 25 O... 64 2e-009
>sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain-containing protein 10 OS=Mus
musculus GN=Tmed10 PE=2 SV=1
Length = 219
Score = 105 bits (261), Expect = 5e-022
Identities = 57/208 (27%), Positives = 109/208 (52%), Gaps = 5/208 (2%)
Frame = -2
Query: 777 NTWTFLLTLAILSGVSQSLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSH 598
+ W FLL L S + S H + S KC+ E+I + + G Y + +H
Sbjct: 16 SAWLFLLLLGPSSVLGISFHLPVNS--RKCLREEIHKDLLVTGAYEITDQSGGAGGLRTH 73
Query: 597 KISIRVTSSYGNTFHHAEDVDSGQFAFTAVEAGDYMACFTANGHKPEVTLSIDFDWRTGI 418
+++T S G+ + ED G+FAFT + + CF + G + D + G+
Sbjct: 74 ---LKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGV 130
Query: 417 HSKSWSSVAKKSQVEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLS 238
+K++ +AK +++ +E E+++L + +I ++ Y++ REEEM++ N +T +++ + S
Sbjct: 131 EAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFS 190
Query: 237 FLSLFVCLGVAGMQFMHLKTFLEKKKVI 154
S+F +G+A Q +L+ F + KK+I
Sbjct: 191 IFSMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain-containing protein 10 OS=Bos
taurus GN=TMED10 PE=2 SV=1
Length = 219
Score = 102 bits (254), Expect = 3e-021
Identities = 56/206 (27%), Positives = 108/206 (52%), Gaps = 5/206 (2%)
Frame = -2
Query: 765 FLLTLAILSGVSQ--SLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKI 592
F L L +L G S ++ F L KC+ E+I + + G Y + +H
Sbjct: 16 FALLLLLLLGPSSVLAISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTH-- 73
Query: 591 SIRVTSSYGNTFHHAEDVDSGQFAFTAVEAGDYMACFTANGHKPEVTLSIDFDWRTGIHS 412
+++T S G+ + ED G+FAFT + + CF + G + D + G+ +
Sbjct: 74 -LKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEA 132
Query: 411 KSWSSVAKKSQVEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFL 232
K++ +AK +++ +E E+++L + +I ++ Y++ REEEM++ N +T +++ + S
Sbjct: 133 KNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIF 192
Query: 231 SLFVCLGVAGMQFMHLKTFLEKKKVI 154
S+F +G+A Q +L+ F + KK+I
Sbjct: 193 SMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain-containing protein 10
OS=Oryctolagus cuniculus GN=TMED10 PE=1 SV=1
Length = 219
Score = 101 bits (249), Expect = 1e-020
Identities = 55/204 (26%), Positives = 107/204 (52%), Gaps = 5/204 (2%)
Frame = -2
Query: 765 FLLTLAILSGVSQSLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISI 586
FL L S ++ S H + S KC+ E+I + + G Y + +H +
Sbjct: 20 FLFLLGPSSVLAISFHLPVNS--RKCLREEIHKDLLVTGAYEITDQSGGAGGLRTH---L 74
Query: 585 RVTSSYGNTFHHAEDVDSGQFAFTAVEAGDYMACFTANGHKPEVTLSIDFDWRTGIHSKS 406
++T S G+ + ED G+FAFT + + CF + G + D + G+ +K+
Sbjct: 75 KITDSAGHILYSKEDASKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKN 134
Query: 405 WSSVAKKSQVEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLSL 226
+ +AK +++ +E E+++L + +I ++ Y++ REEEM++ N +T +++ + S S+
Sbjct: 135 YEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSM 194
Query: 225 FVCLGVAGMQFMHLKTFLEKKKVI 154
F +G+A Q +L+ F + KK+I
Sbjct: 195 FCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q63584|TMEDA_RAT Transmembrane emp24 domain-containing protein 10 OS=Rattus
norvegicus GN=Tmed10 PE=1 SV=2
Length = 219
Score = 100 bits (247), Expect = 2e-020
Identities = 57/212 (26%), Positives = 110/212 (51%), Gaps = 7/212 (3%)
Frame = -2
Query: 789 LRSENTWTFLLTLAILSGVSQSLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPS 610
L S + FLL + + G+S F L KC+ E+I + + G Y +
Sbjct: 14 LLSALLFLFLLGPSSVLGIS----FHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGG 69
Query: 609 PPSHKISIRVTSSYGNTFHHAEDVDSGQFAFTAVEAGDYMACFTANGHKPEVTLSIDFDW 430
+H +++T S G+ + ED G+FAFT + + CF + G + D
Sbjct: 70 LRTH---LKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDM 126
Query: 429 RTGIHSKSWSSVAKKSQVEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKM 250
+ G+ +K++ +AK +++ +E E+++L + +I ++ Y++ REEEM++ N +T +++
Sbjct: 127 KHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRV 186
Query: 249 AWLSFLSLFVCLGVAGMQFMHLKTFLEKKKVI 154
+ S S+F +G+A Q +L+ F + KK+I
Sbjct: 187 LYFSIFSMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain-containing protein 10 OS=Homo
sapiens GN=TMED10 PE=1 SV=2
Length = 219
Score = 99 bits (245), Expect = 3e-020
Identities = 51/191 (26%), Positives = 101/191 (52%), Gaps = 3/191 (1%)
Frame = -2
Query: 726 SLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISIRVTSSYGNTFHHA 547
++ F L KC+ E+I + + G Y + SH +++T S G+ +
Sbjct: 31 AISFHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSH---LKITDSAGHILYSK 87
Query: 546 EDVDSGQFAFTAVEAGDYMACFTANGHKPEVTLSIDFDWRTGIHSKSWSSVAKKSQVEVM 367
ED G+FAFT + + CF + G + D + G+ +K++ +AK +++ +
Sbjct: 88 EDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPL 147
Query: 366 EFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLSLFVCLGVAGMQFMH 187
E E+++L + +I ++ Y++ REEEM++ N +T +++ + S S+F +G+A Q +
Sbjct: 148 EVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFY 207
Query: 186 LKTFLEKKKVI 154
L+ F + KK+I
Sbjct: 208 LRRFFKAKKLI 218
>sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 OS=Mesocricetus auratus
GN=TMED10 PE=2 SV=1
Length = 219
Score = 99 bits (245), Expect = 3e-020
Identities = 55/204 (26%), Positives = 107/204 (52%), Gaps = 5/204 (2%)
Frame = -2
Query: 765 FLLTLAILSGVSQSLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISI 586
FLL L S ++ S H + S KC+ E+I + + G Y + +H +
Sbjct: 20 FLLLLGPSSVLAISFHLPVNS--RKCLREEIHKDLLVTGAYEITDQSGGAGGLRTH---L 74
Query: 585 RVTSSYGNTFHHAEDVDSGQFAFTAVEAGDYMACFTANGHKPEVTLSIDFDWRTGIHSKS 406
++T S G+ + ED G+FAFT + + CF + G + D + G+ +K+
Sbjct: 75 KITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKN 134
Query: 405 WSSVAKKSQVEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLSL 226
+ +AK +++ +E E+++L + +I ++ Y++ REEEM++ N +T +++ + S S+
Sbjct: 135 YEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSM 194
Query: 225 FVCLGVAGMQFMHLKTFLEKKKVI 154
+G+A Q +L+ F + KK+I
Sbjct: 195 LCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q5RE32|TMEDA_PONAB Transmembrane emp24 domain-containing protein 10 OS=Pongo
abelii GN=TMED10 PE=2 SV=1
Length = 219
Score = 99 bits (244), Expect = 4e-020
Identities = 56/204 (27%), Positives = 105/204 (51%), Gaps = 5/204 (2%)
Frame = -2
Query: 759 LTLAILSGVS--QSLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISI 586
L L L G S ++ F L KC+ E+I + + G Y + SH +
Sbjct: 18 LLLLFLLGPSLVLAISFHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSH---L 74
Query: 585 RVTSSYGNTFHHAEDVDSGQFAFTAVEAGDYMACFTANGHKPEVTLSIDFDWRTGIHSKS 406
++T S G+ + ED G+FAFT + + CF + G + D + G+ +K+
Sbjct: 75 KITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKN 134
Query: 405 WSSVAKKSQVEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLSL 226
+ +AK +++ +E E+++L + +I ++ Y+ REEEM++ N +T +++ + S S+
Sbjct: 135 YEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMEKREEEMRDTNESTNTRVLYFSIFSM 194
Query: 225 FVCLGVAGMQFMHLKTFLEKKKVI 154
F +G+A Q +L+ F + KK+I
Sbjct: 195 FCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q90515|TMEDA_TAKRU Transmembrane emp24 domain-containing protein 10
OS=Takifugu rubripes GN=tmed10 PE=3 SV=1
Length = 213
Score = 99 bits (244), Expect = 4e-020
Identities = 57/210 (27%), Positives = 112/210 (53%), Gaps = 7/210 (3%)
Frame = -2
Query: 768 TFLLTLAILSGVSQSLHFELRSGRTKCISEDIKSNSMTVGKYTV---VKPDEAHPSPPSH 598
T LL L +L + S+ F L KC+ E+I + + G+Y + V +
Sbjct: 5 TALLFLPVLIESAFSISFFLPVNTRKCLREEIHKDVLVTGEYEISEQVVTVHTSSTVVGD 64
Query: 597 KISIRVTSSYGNTFHHAEDVDSGQFAFTAVEAGDYMACFTA--NGHKPEVTLSIDFDWRT 424
++T S +T + ED G+FAFT + + CF + G P+ +++D +
Sbjct: 65 GSIFKITDSSSHTLYSKEDATKGKFAFTTEDYDMFEVCFESKCTGRVPDQLVNLDM--KH 122
Query: 423 GIHSKSWSSVAKKSQVEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAW 244
G+ +K++ +AK +++ +E E+++L + +I ++ Y++ REEEM++ N +T +++ +
Sbjct: 123 GVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLY 182
Query: 243 LSFLSLFVCLGVAGMQFMHLKTFLEKKKVI 154
S S+F +G+A Q +L+ F + KK+I
Sbjct: 183 FSIFSMFCLIGLATWQVFYLRRFFKAKKLI 212
>sp|B4NIY1|TMEDA_DROWI Transmembrane emp24 domain-containing protein bai
OS=Drosophila willistoni GN=bai PE=3 SV=1
Length = 206
Score = 94 bits (233), Expect = 8e-019
Identities = 56/207 (27%), Positives = 105/207 (50%), Gaps = 11/207 (5%)
Frame = -2
Query: 762 LLTLAILSGV--SQSLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKIS 589
L TLAI + QS+ F L KC+ EDI++N M +G+Y V P I
Sbjct: 6 LATLAIFGCIWPGQSVMFHLTPNTQKCLKEDIQANQMVMGEYEV-------SDVPGQVID 58
Query: 588 IRVTSSYGNTFHHAEDVDSGQFAFTAVEAGDYMACFTAN--GHKPEVTLSIDFDWRTGIH 415
V + G+ E + +F+F + Y CF + H+ + + + G+
Sbjct: 59 FIVRDTKGHILSQKEHITKAKFSFMSEVYDSYEICFISKVPPHQRGIAQQVALTTKKGVE 118
Query: 414 SKSWSSVAKKSQVEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSF 235
+K++ + + S+++ +E ++K+L + ++I + +R REEEM++ N T S++ + S
Sbjct: 119 TKNYEGIGEASKLKPLEVDLKRLEDLSDSIVRDFVMMRKREEEMRDTNEKTNSRVLFFSI 178
Query: 234 LSLFVCLGVAGMQFMHLKTFLEKKKVI 154
S+ LG+A Q ++L+ + + KK+I
Sbjct: 179 FSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|B3LVB0|TMEDA_DROAN Transmembrane emp24 domain-containing protein bai
OS=Drosophila ananassae GN=bai PE=3 SV=1
Length = 206
Score = 94 bits (231), Expect = 1e-018
Identities = 52/205 (25%), Positives = 104/205 (50%), Gaps = 9/205 (4%)
Frame = -2
Query: 762 LLTLAILSGVSQSLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISIR 583
L TL + +++ F+L KC+ EDI++N + +G+Y V P I
Sbjct: 8 LCTLMAWAWTGEAVMFKLTPNTQKCLKEDIQANQLVIGEYEV-------SDVPGQVIDYI 60
Query: 582 VTSSYGNTFHHAEDVDSGQFAFTAVEAGDYMACFTAN--GHKPEVTLSIDFDWRTGIHSK 409
+ G+ E + G+F+F + Y CF + H+ + + + G+ +K
Sbjct: 61 ARDTKGHILSQQEHITKGKFSFMSEVYDAYEICFISKVPPHQRGIPQEVSLSTKKGVETK 120
Query: 408 SWSSVAKKSQVEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLS 229
S+ + + S+++ +E ++K+L + ++I + +R REEEM++ N T S++ + S S
Sbjct: 121 SYEGIGEASKLKPLEVDLKRLEDLSDSIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFS 180
Query: 228 LFVCLGVAGMQFMHLKTFLEKKKVI 154
+ LG+A Q ++L+ + + KK+I
Sbjct: 181 MCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|B4JYU5|TMEDA_DROGR Transmembrane emp24 domain-containing protein bai
OS=Drosophila grimshawi GN=bai PE=3 SV=2
Length = 206
Score = 91 bits (224), Expect = 9e-018
Identities = 53/208 (25%), Positives = 106/208 (50%), Gaps = 12/208 (5%)
Frame = -2
Query: 762 LLTLAILSGVSQSLH---FELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKI 592
LL + ++ G +H F L KC+ EDI++N + +G+Y V P I
Sbjct: 5 LLCILLIFGCLCRIHGVMFHLTPNTQKCLKEDIQANQLVMGEYEV-------SDVPGQII 57
Query: 591 SIRVTSSYGNTFHHAEDVDSGQFAFTAVEAGDYMACFTAN--GHKPEVTLSIDFDWRTGI 418
+ G+ E + G+F+FT+ Y CF + H+ ++ + + G+
Sbjct: 58 DYIARDTKGHILSQKEHITKGKFSFTSEVFDAYEICFISKVPPHQRGISQEVSLVTKKGV 117
Query: 417 HSKSWSSVAKKSQVEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLS 238
+K++ + + S+++ +E ++K+L + ++I + +R REEEM++ N T S++ + S
Sbjct: 118 ETKNYEGIGEASKLKPLEVDLKRLEDLSDSIVRDFAVMRKREEEMRDTNEKTNSRVLFFS 177
Query: 237 FLSLFVCLGVAGMQFMHLKTFLEKKKVI 154
S+ LG+A Q ++L+ + + KK+I
Sbjct: 178 IFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|A0AQ71|TMEDA_DROSI Transmembrane emp24 domain-containing protein bai
OS=Drosophila simulans GN=bai PE=3 SV=1
Length = 206
Score = 91 bits (223), Expect = 1e-017
Identities = 51/195 (26%), Positives = 100/195 (51%), Gaps = 9/195 (4%)
Frame = -2
Query: 732 SQSLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISIRVTSSYGNTFH 553
S ++ F+L KC+ EDI++N + +G+Y V P I + G+
Sbjct: 18 SHAVMFKLSPNTQKCLKEDIQANQLVMGEYEV-------SDVPGQIIDYIARDTKGHILS 70
Query: 552 HAEDVDSGQFAFTAVEAGDYMACFTAN--GHKPEVTLSIDFDWRTGIHSKSWSSVAKKSQ 379
E + G+F+F + Y CF + H+ V + + G+ +KS+ + + S+
Sbjct: 71 QKEHITKGKFSFMSEVYETYEICFISKVPAHQRGVVQEVSLLTKKGVETKSYEGIGEASK 130
Query: 378 VEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLSLFVCLGVAGM 199
++ +E ++K+L + ++I + +R REEEM++ N T S++ + S S+ LG+A
Sbjct: 131 LKPLEVDLKRLEDLSDSIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATW 190
Query: 198 QFMHLKTFLEKKKVI 154
Q ++L+ + + KK+I
Sbjct: 191 QVLYLRRYFKAKKLI 205
>sp|B3P6T8|TMEDA_DROER Transmembrane emp24 domain-containing protein bai
OS=Drosophila erecta GN=bai PE=3 SV=1
Length = 206
Score = 90 bits (222), Expect = 2e-017
Identities = 50/195 (25%), Positives = 100/195 (51%), Gaps = 9/195 (4%)
Frame = -2
Query: 732 SQSLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISIRVTSSYGNTFH 553
S ++ F+L KC+ EDI++N + +G+Y V P I + G+
Sbjct: 18 SHAVMFKLSPNTQKCLKEDIQANQLVMGEYEV-------SDVPGQIIDYIARDTKGHILS 70
Query: 552 HAEDVDSGQFAFTAVEAGDYMACFTAN--GHKPEVTLSIDFDWRTGIHSKSWSSVAKKSQ 379
E + G+F+F + Y CF + H+ + + + G+ +KS+ + + S+
Sbjct: 71 QKEHITKGKFSFMSEVYDAYEICFISKVPAHQRGIVQEVSLLTKKGVETKSYEGIGEASK 130
Query: 378 VEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLSLFVCLGVAGM 199
++ +E ++K+L + ++I + +R REEEM++ N T S++ + S S+ LG+A
Sbjct: 131 LKPLEVDLKRLEDLSDSIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATW 190
Query: 198 QFMHLKTFLEKKKVI 154
Q ++L+ + + KK+I
Sbjct: 191 QVLYLRRYFKAKKLI 205
>sp|B4PUZ3|TMEDA_DROYA Transmembrane emp24 domain-containing protein bai
OS=Drosophila yakuba GN=bai PE=3 SV=1
Length = 206
Score = 90 bits (222), Expect = 2e-017
Identities = 50/195 (25%), Positives = 100/195 (51%), Gaps = 9/195 (4%)
Frame = -2
Query: 732 SQSLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISIRVTSSYGNTFH 553
S ++ F+L KC+ EDI++N + +G+Y V P I + G+
Sbjct: 18 SHAVMFKLSPNTQKCLKEDIQANQLVMGEYEV-------SDVPGQIIDYIARDTKGHILS 70
Query: 552 HAEDVDSGQFAFTAVEAGDYMACFTAN--GHKPEVTLSIDFDWRTGIHSKSWSSVAKKSQ 379
E + G+F+F + Y CF + H+ + + + G+ +KS+ + + S+
Sbjct: 71 QKEHITKGKFSFMSEVYDAYEICFISKVPAHQRGIVQEVSLLTKKGVETKSYEGIGEASK 130
Query: 378 VEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLSLFVCLGVAGM 199
++ +E ++K+L + ++I + +R REEEM++ N T S++ + S S+ LG+A
Sbjct: 131 LKPLEVDLKRLEDLSDSIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATW 190
Query: 198 QFMHLKTFLEKKKVI 154
Q ++L+ + + KK+I
Sbjct: 191 QVLYLRRYFKAKKLI 205
>sp|Q8SXY6|TMEDA_DROME Transmembrane emp24 domain-containing protein bai
OS=Drosophila melanogaster GN=bai PE=2 SV=1
Length = 206
Score = 89 bits (219), Expect = 4e-017
Identities = 50/195 (25%), Positives = 100/195 (51%), Gaps = 9/195 (4%)
Frame = -2
Query: 732 SQSLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISIRVTSSYGNTFH 553
S ++ F+L KC+ EDI++N + +G++ V P I + G+
Sbjct: 18 SHAVMFKLSPNTQKCLKEDIQANQLVMGEFEV-------SDVPGQIIDYIARDTKGHILS 70
Query: 552 HAEDVDSGQFAFTAVEAGDYMACFTAN--GHKPEVTLSIDFDWRTGIHSKSWSSVAKKSQ 379
E + G+F+F + Y CF + H+ V + + G+ +KS+ + + S+
Sbjct: 71 QKEHITKGKFSFMSEVYDTYEICFISKVPAHQRGVIQEVSLLTKKGVETKSYEGIGEASK 130
Query: 378 VEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLSLFVCLGVAGM 199
++ +E ++K+L + ++I + +R REEEM++ N T S++ + S S+ LG+A
Sbjct: 131 LKPLEVDLKRLEDLSDSIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATW 190
Query: 198 QFMHLKTFLEKKKVI 154
Q ++L+ + + KK+I
Sbjct: 191 QVLYLRRYFKAKKLI 205
>sp|B4K4G5|TMEDA_DROMO Transmembrane emp24 domain-containing protein bai
OS=Drosophila mojavensis GN=bai PE=3 SV=1
Length = 206
Score = 89 bits (219), Expect = 4e-017
Identities = 50/193 (25%), Positives = 99/193 (51%), Gaps = 9/193 (4%)
Frame = -2
Query: 726 SLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISIRVTSSYGNTFHHA 547
S+ F L KC+ EDI++N + +G+Y V P I + G+
Sbjct: 20 SVMFHLPPNTQKCLKEDIQANQLVMGEYEV-------SDVPGQVIDYIARDTKGHILSQK 72
Query: 546 EDVDSGQFAFTAVEAGDYMACFTAN--GHKPEVTLSIDFDWRTGIHSKSWSSVAKKSQVE 373
E + G+F+F + Y CF + H+ ++ + + G+ +KS+ + + S+++
Sbjct: 73 EHITKGKFSFMSEVYDAYEICFISKVPPHQRGISQEVSLVTKKGVETKSYEGIGEASKLK 132
Query: 372 VMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLSLFVCLGVAGMQF 193
+E ++K+L + ++I + +R REEEM++ N T S++ + S S+ LG+A Q
Sbjct: 133 PLEVDLKRLEDLSDSIVRDFALMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQV 192
Query: 192 MHLKTFLEKKKVI 154
++L+ + + KK+I
Sbjct: 193 LYLRRYFKAKKLI 205
>sp|B4GE47|TMEDA_DROPE Transmembrane emp24 domain-containing protein bai
OS=Drosophila persimilis GN=bai PE=3 SV=1
Length = 206
Score = 89 bits (219), Expect = 4e-017
Identities = 50/193 (25%), Positives = 98/193 (50%), Gaps = 9/193 (4%)
Frame = -2
Query: 726 SLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISIRVTSSYGNTFHHA 547
S+ F L KC+ EDI++N + +G+Y V P I + G+
Sbjct: 20 SVMFNLAPNTQKCLKEDIQANQLVMGEYEV-------SDVPGQIIDYVARDTKGHILSQK 72
Query: 546 EDVDSGQFAFTAVEAGDYMACFTAN--GHKPEVTLSIDFDWRTGIHSKSWSSVAKKSQVE 373
E + G+F+F + Y CF + H+ + + + G+ +KS+ + + S+++
Sbjct: 73 EHITKGKFSFMSEVYDAYEICFISKVPPHQRGIPQEVSLVTKKGVETKSYEGIGEASKLK 132
Query: 372 VMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLSLFVCLGVAGMQF 193
+E ++K+L + ++I + +R REEEM++ N T S++ + S S+ LG+A Q
Sbjct: 133 PLEVDLKRLEDLSDSIVRDFILMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQV 192
Query: 192 MHLKTFLEKKKVI 154
++L+ + + KK+I
Sbjct: 193 LYLRRYFKAKKLI 205
>sp|B4MGF8|TMEDA_DROVI Transmembrane emp24 domain-containing protein bai
OS=Drosophila virilis GN=bai PE=3 SV=1
Length = 206
Score = 89 bits (219), Expect = 4e-017
Identities = 50/193 (25%), Positives = 99/193 (51%), Gaps = 9/193 (4%)
Frame = -2
Query: 726 SLHFELRSGRTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISIRVTSSYGNTFHHA 547
S+ F L KC+ EDI++N + +G+Y V P I + G+
Sbjct: 20 SVMFHLTPNTQKCLKEDIQANQLVMGEYEV-------SDVPGQIIDYIARDTKGHILSQK 72
Query: 546 EDVDSGQFAFTAVEAGDYMACFTAN--GHKPEVTLSIDFDWRTGIHSKSWSSVAKKSQVE 373
E + G+F+F + Y CF + H+ ++ + + G+ +KS+ + + S+++
Sbjct: 73 EHITKGKFSFMSEVYDAYEICFISKVPPHQRGISQEVSLVTKKGVETKSYEGIGEASKLK 132
Query: 372 VMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLSLFVCLGVAGMQF 193
+E ++K+L + ++I + +R REEEM++ N T S++ + S S+ LG+A Q
Sbjct: 133 PLEVDLKRLEDLSDSIVRDFALMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQV 192
Query: 192 MHLKTFLEKKKVI 154
++L+ + + KK+I
Sbjct: 193 LYLRRYFKAKKLI 205
>sp|Q9D2R4|TMD11_MOUSE Transmembrane emp24 domain-containing protein 11 OS=Mus
musculus GN=Tmed11 PE=2 SV=1
Length = 215
Score = 67 bits (161), Expect = 2e-010
Identities = 48/181 (26%), Positives = 81/181 (44%), Gaps = 5/181 (2%)
Frame = -2
Query: 684 SEDIKSNSMTVGKYTVVKPDEAHPSPPSHKISIRVTSSYGNTFHHAEDVDSGQFAFTAVE 505
S+ + + + V ++ +V+ D S P + + VT+ G F FT+
Sbjct: 36 SDTLITGTFKVQQWDIVRHDFLE-SAPGLGMFVTVTTYNDEVLLSKLYGAQGTFYFTSHS 94
Query: 504 AGDYMACFTANGHK----PEVTLSIDFDWRTGIHSKSWSSVAKKSQVEVMEFEVKQLIET 337
+G+++ C +N + L I D R G H + V K +V + F+++ LIE
Sbjct: 95 SGEHIICLESNSTQFVSFGGSKLRIHLDIRVGEHDLDAAIVQAKDKVNEVTFKLQHLIEQ 154
Query: 336 VNTIHDEMFYLRDREEEMQNLNRATISKMAWLSFLSLFVCLGVAGMQFMHLKTFLEKKKV 157
V I E Y RDREE + + T + W +F + + + V Q HLK F KK+
Sbjct: 155 VEQILKEQDYQRDREENFRITSEDTNRNVLWWAFAQILIFISVGIFQMKHLKDFFIAKKL 214
Query: 156 I 154
+
Sbjct: 215 V 215
>sp|Q4WQL0|TMEDA_ASPFU Endoplasmic reticulum vesicle protein 25 OS=Aspergillus
fumigatus GN=erv25 PE=3 SV=1
Length = 266
Score = 64 bits (153), Expect = 2e-009
Identities = 48/208 (23%), Positives = 100/208 (48%), Gaps = 23/208 (11%)
Frame = -2
Query: 759 LTLAILSGVSQSLHFELRSG---RTKCISEDIKSNSMTVGKYTVVKPDEAHPSPPSHKIS 589
L +L +S +L F+L + +CI N + + VV + ++
Sbjct: 15 LLFLLLVQLSSALKFDLHASSGHNERCI-----RNFVFKDQLVVVTAIVSGQRGDGQVVN 69
Query: 588 IRVTSSYGNTFHHAEDV-DSGQFAFTAVEAGDYMACF---------TANGHKPEVTLSID 439
+ + + GN +D+ + AFT+V + CF AN +K S++
Sbjct: 70 MHIKDALGNDHGRPKDIAGETRQAFTSVADTAFDVCFENKLVSHHGVANPYK-----SVE 124
Query: 438 FDWRTGIHSKSWSSVAKKSQVEVMEFEVKQLIETVNTIHDEMFYLRDREEEMQNLNRATI 259
D G ++ WSSV +++ +E +++++ E V I +EM YLR RE+++++ N +T
Sbjct: 125 LDVEIGADARDWSSVQAAEKLKPVETDLRRIEEMVAEIVNEMEYLRAREQKLRDTNESTN 184
Query: 258 SKMAWLSFLSLFVCLGVAGMQFMHLKTF 175
++ W +F ++ + +G+ Q ++L+ +
Sbjct: 185 ERVKWFAFGTMGMLVGLGVWQVVYLRAY 212
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0
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