BLASTX 7.6.2
Query= UN17113 /QuerySize=1067
(1066 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O49048|VPS45_ARATH Vacuolar protein sorting-associated protei... 565 3e-160
sp|Q54GE3|VPS45_DICDI Vacuolar protein sorting-associated protei... 252 3e-066
sp|P97390|VPS45_MOUSE Vacuolar protein sorting-associated protei... 250 1e-065
sp|Q9NRW7|VPS45_HUMAN Vacuolar protein sorting-associated protei... 250 2e-065
sp|O08700|VPS45_RAT Vacuolar protein sorting-associated protein ... 249 3e-065
sp|Q09805|YAB3_SCHPO Putative vacuolar protein sorting-associate... 202 4e-051
sp|P38932|VPS45_YEAST Vacuolar protein sorting-associated protei... 111 2e-023
>sp|O49048|VPS45_ARATH Vacuolar protein sorting-associated protein 45 homolog
OS=Arabidopsis thaliana GN=VPS45 PE=1 SV=2
Length = 569
Score = 565 bits (1454), Expect = 3e-160
Identities = 286/292 (97%), Positives = 288/292 (98%)
Frame = +1
Query: 4 QDAFFKSNMYENFGDIGMNIKRMVDDFQQVAKSNQNIQTVEDMARFVDNYPEYKKMQGNV 183
QDAFFKSNMYENFGDIGMNIKRMVDDFQQVAKSNQNIQTVEDMARFVDNYPEYKKMQGNV
Sbjct: 278 QDAFFKSNMYENFGDIGMNIKRMVDDFQQVAKSNQNIQTVEDMARFVDNYPEYKKMQGNV 337
Query: 184 SKHVTLVTEMSKLVEARKLMLVSQTEQDLACNGGQGAAYEAVTDLLNNESVSDIDRLRLV 363
SKHVTLVTEMSKLVEARKLM VSQTEQDLACNGGQGAAYEAVTDLLNNESVSDIDRLRLV
Sbjct: 338 SKHVTLVTEMSKLVEARKLMTVSQTEQDLACNGGQGAAYEAVTDLLNNESVSDIDRLRLV 397
Query: 364 MLYALRYEKENPVQLMQLFNKLASRSPKYKQGLVQFLLKQAGVEKRTGDLFGNRDLLNIA 543
MLYALRYEKENPVQLMQLFNKLASRSPKYK GLVQFLLKQAGVEKRTGDLFGNRDLLNIA
Sbjct: 398 MLYALRYEKENPVQLMQLFNKLASRSPKYKPGLVQFLLKQAGVEKRTGDLFGNRDLLNIA 457
Query: 544 RNMARGLKGVENVYTQHQPLLFQTMESITRGRLRDVDYPFVGDHFQQGRPQEVVIFMVGG 723
RNMARGLKGVENVYTQHQPLLFQTMESITRGRLRDVDYPFVGDHFQQGRPQEVVIFMVGG
Sbjct: 458 RNMARGLKGVENVYTQHQPLLFQTMESITRGRLRDVDYPFVGDHFQQGRPQEVVIFMVGG 517
Query: 724 TTYEESRCVALQNSTNSGIRFILGGTAVLNSKRFLMDLEEAQRISRSGSHMV 879
TTYEESR VALQN+TNSG+RFILGGTAVLNSKRFL DLEEAQRISRSGSHMV
Sbjct: 518 TTYEESRSVALQNATNSGVRFILGGTAVLNSKRFLKDLEEAQRISRSGSHMV 569
>sp|Q54GE3|VPS45_DICDI Vacuolar protein sorting-associated protein 45
OS=Dictyostelium discoideum GN=vps45 PE=1 SV=1
Length = 563
Score = 252 bits (643), Expect = 3e-066
Identities = 127/291 (43%), Positives = 195/291 (67%), Gaps = 6/291 (2%)
Frame = +1
Query: 7 DAFFKSNMYENFGDIGMNIKRMVDDFQQVAKSNQNIQTVEDMARFVDNYPEYKKMQGNVS 186
D F+K N+Y+NFGD+G +IK +VD FQ +NQNIQT++DM +F++NYP ++K VS
Sbjct: 272 DIFYKENLYKNFGDLGASIKDLVDQFQDKMNTNQNIQTIDDMKKFIENYPNFQKFSTTVS 331
Query: 187 KHVTLVTEMSKLVEARKLMLVSQTEQDLACNGGQGAAYEAVTDLLNNESVSDIDRLRLVM 366
KHV+L+ E+++L+ LM VS+ +Q+LACN + Y V +++N+ +D D+L LV+
Sbjct: 332 KHVSLMDELNRLISLDNLMEVSEVQQELACNHDHNSIYNHVLEIVNDSKYTDRDKLVLVL 391
Query: 367 LYALRYEKENPVQLMQLFNKLASRS-PKYKQGLVQFLLKQAGVEKRTGDLFGNRDLLNIA 543
LY++RYE ++ +L KL+S P + GL+ L AG R GDL G +++ + A
Sbjct: 392 LYSIRYEDG---RVWELKEKLSSIGIPPKEIGLIDTLRGYAGASLREGDLLGTKNIFSFA 448
Query: 544 RNMA-RGLKGVENVYTQHQPLLFQTMESITRGRLRDVDYPFVGDHFQQGRPQEVVIFMVG 720
R++ RGL+GV N+YTQH+PLL ++SI + +L++ YP++ + RPQ+V+IFMVG
Sbjct: 449 RSVVKRGLQGVSNIYTQHKPLLHDILDSILKNKLKETSYPYLSTTQSRERPQDVIIFMVG 508
Query: 721 GTTYEESRCVALQNSTNSGI-RFILGGTAVLNSKRFLMDLEEAQRISRSGS 870
G TYEE+ V NS N+G+ R +LGGT++LN ++FL DL Q + S S
Sbjct: 509 GITYEEALTVYTFNSLNTGVCRVVLGGTSILNREQFLEDLSSTQISNPSSS 559
>sp|P97390|VPS45_MOUSE Vacuolar protein sorting-associated protein 45 OS=Mus
musculus GN=Vps45 PE=1 SV=1
Length = 570
Score = 250 bits (638), Expect = 1e-065
Identities = 128/289 (44%), Positives = 190/289 (65%), Gaps = 4/289 (1%)
Frame = +1
Query: 7 DAFFKSNMYENFGDIGMNIKRMVDDFQQV-AKSNQNIQTVEDMARFVDNYPEYKKMQGNV 183
D F+ +NMY NF +IG NIK +++DFQ+ K Q ++++ DM FV+NYP++KKM G V
Sbjct: 269 DEFYANNMYLNFAEIGSNIKNLMEDFQKKRPKEQQKLESIADMKAFVENYPQFKKMSGTV 328
Query: 184 SKHVTLVTEMSKLVEARKLMLVSQTEQDLACNGGQGAAYEAVTDLLNNESVSDIDRLRLV 363
SKHVT+V E+S+LV R L+ VS+ EQ+LAC +A + V LL N V++ D +RLV
Sbjct: 329 SKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNVKRLLQNPKVTEFDAVRLV 388
Query: 364 MLYALRYEKENPVQLMQLFNKLASR--SPKYKQGLVQFLLKQAGVEKRTGDLFGNRDLLN 537
MLYAL YE+ + L L L S+ + KY++ LV +++ G R DLF +D +
Sbjct: 389 MLYALHYERHSSNSLPGLIVDLRSKGVAEKYRK-LVSAVVEYGGKRVRGSDLFSPKDAVA 447
Query: 538 IARNMARGLKGVENVYTQHQPLLFQTMESITRGRLRDVDYPFVGDHFQQGRPQEVVIFMV 717
I + +GLKGVENVYTQHQP L +T++ + +GRL++ YP++G + RPQ++++F++
Sbjct: 448 ITKQFLKGLKGVENVYTQHQPFLHETLDHLIKGRLKENLYPYLGPSTLRDRPQDIIVFII 507
Query: 718 GGTTYEESRCVALQNSTNSGIRFILGGTAVLNSKRFLMDLEEAQRISRS 864
GG TYEE+ V N T G+R +LGGT + N+K FL ++ + SRS
Sbjct: 508 GGATYEEALTVYNLNRTTPGVRIVLGGTTIHNTKSFLEEVLASGLHSRS 556
>sp|Q9NRW7|VPS45_HUMAN Vacuolar protein sorting-associated protein 45 OS=Homo
sapiens GN=VPS45 PE=1 SV=1
Length = 570
Score = 250 bits (637), Expect = 2e-065
Identities = 130/291 (44%), Positives = 190/291 (65%), Gaps = 8/291 (2%)
Frame = +1
Query: 7 DAFFKSNMYENFGDIGMNIKRMVDDFQ-QVAKSNQNIQTVEDMARFVDNYPEYKKMQGNV 183
D F+ +NMY NF +IG NIK +++DFQ + K Q ++++ DM FV+NYP++KKM G V
Sbjct: 269 DEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAFVENYPQFKKMSGTV 328
Query: 184 SKHVTLVTEMSKLVEARKLMLVSQTEQDLACNGGQGAAYEAVTDLLNNESVSDIDRLRLV 363
SKHVT+V E+S+LV R L+ VS+ EQ+LAC +A + + LL N V++ D RLV
Sbjct: 329 SKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLV 388
Query: 364 MLYALRYEKEN----PVQLMQLFNKLASRSPKYKQGLVQFLLKQAGVEKRTGDLFGNRDL 531
MLYAL YE+ + P +M L NK S KY++ LV +++ G R DLF +D
Sbjct: 389 MLYALHYERHSSNSLPGLMMDLRNK--GVSEKYRK-LVSAVVEYGGKRVRGSDLFSPKDA 445
Query: 532 LNIARNMARGLKGVENVYTQHQPLLFQTMESITRGRLRDVDYPFVGDHFQQGRPQEVVIF 711
+ I + +GLKGVENVYTQHQP L +T++ + +GRL++ YP++G + RPQ++++F
Sbjct: 446 VAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKGRLKENLYPYLGPSTLRDRPQDIIVF 505
Query: 712 MVGGTTYEESRCVALQNSTNSGIRFILGGTAVLNSKRFLMDLEEAQRISRS 864
++GG TYEE+ V N T G+R +LGGT V N+K FL ++ + SRS
Sbjct: 506 VIGGATYEEALTVYNLNRTTPGVRIVLGGTTVHNTKSFLEEVLASGLHSRS 556
>sp|O08700|VPS45_RAT Vacuolar protein sorting-associated protein 45 OS=Rattus
norvegicus GN=Vps45 PE=2 SV=1
Length = 570
Score = 249 bits (635), Expect = 3e-065
Identities = 127/289 (43%), Positives = 190/289 (65%), Gaps = 4/289 (1%)
Frame = +1
Query: 7 DAFFKSNMYENFGDIGMNIKRMVDDFQQV-AKSNQNIQTVEDMARFVDNYPEYKKMQGNV 183
D F+ +NMY NF +IG NIK +++DFQ+ K Q ++++ DM FV+NYP++KKM G V
Sbjct: 269 DEFYANNMYLNFAEIGSNIKNLMEDFQKKRPKEQQKLESIADMKAFVENYPQFKKMSGTV 328
Query: 184 SKHVTLVTEMSKLVEARKLMLVSQTEQDLACNGGQGAAYEAVTDLLNNESVSDIDRLRLV 363
SKHVT+V E+S+LV R L+ VS+ EQ+LAC +A + V LL N V++ D +RLV
Sbjct: 329 SKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNVKRLLQNPKVTEFDAVRLV 388
Query: 364 MLYALRYEKENPVQLMQLFNKLASR--SPKYKQGLVQFLLKQAGVEKRTGDLFGNRDLLN 537
MLYAL YE+ + L L L S+ + KY++ LV +++ G R DLF +D +
Sbjct: 389 MLYALHYERHSSNSLPGLIVDLRSKGVAEKYRK-LVSAVVEYGGKRVRGSDLFSPKDAVA 447
Query: 538 IARNMARGLKGVENVYTQHQPLLFQTMESITRGRLRDVDYPFVGDHFQQGRPQEVVIFMV 717
I + +GLKGVENVYTQHQP L +T++ + +G+L++ YP++G + RPQ++++F++
Sbjct: 448 ITKQFLKGLKGVENVYTQHQPFLHETLDHLIKGKLKENLYPYLGPSTLRDRPQDIIVFVI 507
Query: 718 GGTTYEESRCVALQNSTNSGIRFILGGTAVLNSKRFLMDLEEAQRISRS 864
GG TYEE+ V N T G+R +LGGT + N+K FL ++ + SRS
Sbjct: 508 GGATYEEALTVYNLNRTTPGVRIVLGGTTIHNTKSFLEEVLASGLHSRS 556
>sp|Q09805|YAB3_SCHPO Putative vacuolar protein sorting-associated protein
C2G11.03c OS=Schizosaccharomyces pombe GN=SPAC2G11.03c PE=2 SV=1
Length = 558
Score = 202 bits (513), Expect = 4e-051
Identities = 107/283 (37%), Positives = 173/283 (61%), Gaps = 7/283 (2%)
Frame = +1
Query: 7 DAFFKSNMYENFGDIGMNIKRMVDDFQ-QVAKSNQNIQTVEDMARFVDNYPEYKKMQGNV 183
D F+K ++NFGD+G+ IK V Q + K I+++ DM +F++ YPEY+++ GNV
Sbjct: 269 DPFYKETRFDNFGDLGVKIKDYVSHLQTKSTKKASEIESIADMKQFLEAYPEYRRLSGNV 328
Query: 184 SKHVTLVTEMSKLVEARKLMLVSQTEQDLACNGGQGAAYEAVTDLLNNESVSDIDRLRLV 363
SKHV+LV+E+S++V+ L+ V + EQ L CN Q + + LL + ++S+ +LRL
Sbjct: 329 SKHVSLVSEISQVVQRENLLEVGEVEQSLVCNEPQSTDFNDIQRLLFS-NISENTKLRLA 387
Query: 364 MLYALRYEKENPVQLMQLFNKL-ASRSPKYKQGLVQFLLKQAGVEKRTGDLFGNRDLLNI 540
LY+LR+E+ +P ++ L L A K ++ LL AG R GD+F +L +
Sbjct: 388 ALYSLRFERIDPAKVSALQQMLIAGGVNPLKVSVIPTLLHVAGYSFRQGDVFPPSNLFSR 447
Query: 541 ARNMARGLKGVENVYTQHQPLLFQTMESITRGRLRDVDYPFVGDHFQ----QGRPQEVVI 708
AR+ +GL+GVENVY QH P L + + +GRL++ +PF+ + +PQ++++
Sbjct: 448 ARSGLKGLRGVENVYIQHNPFLKSILLDLIQGRLKETTHPFLNSETRAQTSNEKPQDIIV 507
Query: 709 FMVGGTTYEESRCVALQNSTNSGIRFILGGTAVLNSKRFLMDL 837
+VGG TYEE+ V+ N+T G+R IL GT +LNS ++ D+
Sbjct: 508 VIVGGATYEEAHFVSEFNATQPGVRIILAGTTILNSTAYIDDI 550
>sp|P38932|VPS45_YEAST Vacuolar protein sorting-associated protein 45
OS=Saccharomyces cerevisiae GN=VPS45 PE=1 SV=2
Length = 577
Score = 111 bits (275), Expect = 2e-023
Identities = 63/222 (28%), Positives = 116/222 (52%), Gaps = 13/222 (5%)
Frame = +1
Query: 4 QDAFFKSNMYENFGDIGMNIKRMVDDFQQVAKSNQNIQTVEDMARFVDNYPEYKKMQGNV 183
QDAFF+ MY NFG++G +K+ V ++ ++N I ++ED+ F++ YPE++K+ GNV
Sbjct: 282 QDAFFRDTMYLNFGELGDKVKQYVTTYKDKTQTNSQINSIEDIKNFIEKYPEFRKLSGNV 341
Query: 184 SKHVTLVTEMSKLVEARKLMLVSQTEQDLACNGGQGAAYEAVTDLLNNESVSDIDRLRLV 363
+KH+ +V E+ + ++ + + +S+ EQ+L+ + + + LL NE+V +L+L
Sbjct: 342 AKHMAIVGELDRQLKIKNIWEISEIEQNLSAHDANEEDFSDLIKLLQNEAVDKYYKLKLA 401
Query: 364 MLYALRYEKENPVQLMQLFNKLASRSPKYKQGLVQFLLKQAGVEKRTGDLF-GNRDLLNI 540
+Y+L + + ++ QL L+ + P V F K + R + N D +I
Sbjct: 402 CIYSLNNQTSSD-KIRQLVEILSQQLPPED---VNFFHKFKSLFSRQDKMTQSNHDKDDI 457
Query: 541 ARNMARGLKG--------VENVYTQHQPLLFQTMESITRGRL 642
+AR ENVY QH P + + +++ L
Sbjct: 458 LTELARRFNSRMNSKSNTAENVYMQHIPEISSLLTDLSKNAL 499
Score = 57 bits (136), Expect = 2e-007
Identities = 27/80 (33%), Positives = 53/80 (66%), Gaps = 4/80 (5%)
Frame = +1
Query: 622 SITRGRLRDVD---YPFVGDHFQQGRPQEVVIFMVGGTTYEESRCVALQNST-NSGIRFI 789
++ R R +++D + +G+ + PQ+V++F++GG TYEE+R V N T N+ +R +
Sbjct: 498 ALFRDRFKEIDTQGHRVIGNQQSKDIPQDVILFVIGGVTYEEARLVHDFNGTMNNRMRVV 557
Query: 790 LGGTAVLNSKRFLMDLEEAQ 849
LGGT++L++K ++ + A+
Sbjct: 558 LGGTSILSTKEYMDSIRSAK 577
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0
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